Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients

Journal of Experimental Medicine

Volumn 184, Issue 4, 1996, Pages 1519-1524

  McInnes, Iain B ^a,b   Leung, Bernard P ^a   Field, Max ^b   Wei, Xiao Q ^a   Huang, Fang Ping ^a   Sturrock, Roger D ^b   Kinninmonth, Andrew ^c   Weidner, Jeffrey ^d   Mumford, Richard ^d   Liew, Foo Y ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b University Department of Medicine   (United Kingdom)

^c GLASGOW ROYAL INFIRMARY   (United Kingdom)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; MONOCLONAL ANTIBODY CD68; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NONSPECIFIC ESTERASE; STAPHYLOCOCCUS ENTEROTOXIN B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; OSTEOARTHRITIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; ARTHROPLASTY; CELLS, CULTURED; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MIDDLE AGED; NITRIC OXIDE; OSTEOARTHRITIS; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 10244253892     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.4.1519     Document Type: Article

References (28)

1. Feldmann, M., F.M. Brennan, and R.N. Maini. 1996. Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14: 397-440.
2. Moncada, S., and A. Higgs. 1993. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 329:2002-2012.
3. Nathan, C., Q.-W. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725-13728.
4. McCartney-Francis, N., J.B. Allen, D.E. Mizel, J.E. Albina, Q. Xie, C.F. Nathan, and S. Wahl. 1993. Suppression of arthritis by an inhibitor of nitric oxide synthase. J. Exp. Med. 178:749-754.
5. Stefanovic-Racic, M., K. Meyers, C. Meschter, J.W. Coffey, R.A. Hoffman, and C.H. Evans. 1994. N-Monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats. Arthr. Rheum. 37: 1062-1069.
6. Weinberg, J.B., D.L. Granger, D.S. Pisetsky, M.F. Seldin, M. Misukonis, S.N. Mason, A.M. Pippen, P. Ruiz, E.R. Wood, and G.S. Gilken. 1994. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and NO synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered L-NMMA. J. Exp. Med. 179:651-660.
7. Huang, F.-P., G.-J. Feng, G. Lindop, D. Stott, and F.Y. Liew. 1996. The role of IL-12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. J. Exp. Med. 183:1447-1459.
8. Charles, I.G., R.J. Palmer, M.S. Hickery, M.T. Bayliss, A.P. Chubb, V.S. Hall, D.W. Moss, and S. Moncada. 1993. Cloning, characterization and expression of a cDNA encoding an inducible nitric oxide synthase from human chondrocytes. Proc. Natl. Acad. Sci. USA. 90:11419-1142.
9. Barnes, P.J., and F.Y. Liew. 1994. Nitric oxide and asthmatic inflammation. Immunol. Today. 16:128-130.
10. Stefanovic-Racic, M., J. Stadler, G.I. Georgescu, C. Evans. 1994. Nitric oxide synthesis and its regulation by rabbit synoviocytes. J. Rheumatol. 21:1892-1898.
11. Farrell, A.J., D.R. Blake, R.M.J. Palmer, and S. Moncada. 1992. Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. Ann. Rheum. Dis. 51:1219-1222.
12. Grabowski, P.S., A. England, R. Dykhuizen, M. Copland, N. Benjamin, D. Reid, and S. Ralston. 1996. Elevated nitric oxide production in rheumatoid arthritis. Arthr. Rheum. 39: 642-647.
13. Sakurai, H., H. Kohsaka, M-F. Liu, H. Higashiyama, Y. Hirata, K. Kanno, I. Saito, and N. Miyasaki. 1995. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J. Clin. Invest. 96:2357-2363.
14. Arnett, F.C., S.M. Edworthy, D.A. Bloch, D.J. McShane, J.F. Fries, N.S. Cooper, L.A. Healey, S.R. Kaplan, M.H. Liang, H.S. Luthra et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthr. Rheum. 31:315-324.
15. Brennan, F.M., D. Chantry, A. Jackson, R. Maini, and M. Feldmann. 1989. Inhibitory effect of TNFα antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet. ii:244-247.
16. Nicholson, S., M.G. Bonecini-Almeida, J.R. Lapa e Silva, C. Nathan, Q-W. Xie, R. Mumford, J.R. Weidner, J. Calaycay, J. Geng, N. Boechat, et al. 1996. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J. Exp. Med. 183:2293-2302.
17. Mueller, J., G. Brundelre, H. Buerki, H.V. Keller, M.W. Hess, and H. Cottier. 1975. Nonspecific acid esterase activity: a criterion for differentiation of T and B lymphocytes in mouse lymph nodes. Eur. J. Immol. 5:270-274.
18. Marrack, P., and J. Kappler. 1990. The staphylococcal enterotoxins and their relatives. Science (Wash. DC). 248:705-711.
19. Trede, N., R.S. Geha, and T. Chatila. 1991. Transcriptional activation of monokine genes by MHC class II ligands. J. Immunol. 146:2310-2315.
20. Murrell, G.A.C., M.M. Dolan, D. Jang, C. Szabo, R.F. Warren, and J.A. Hannafin. 1996. Nitric oxide: an important articular free radical. J. Bone. Joint Surg. 78A:265-274.
21. Schneemann, M., G. Schoedon, S. Hoefer, N. Blau, L. Guerrero, and A. Schaffner. 1993. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J. Infect. Dis. 167:1358-1363.
22. Dugas, B., M. Djavad Mossalayi, C. Damais, and J.P. Kolb. 1995. Nitric oxide production by human monocytes: evidence for a role of CD23. Immunol. Today. 16:574-580.
23. McInnes, I.B., J. Al-Mughales, M. Field, B. Leung, F-P. Huang, R. Dixon, R.D. Sturrock, P.C. Wilkinson, and F.Y. Liew. 1996. A role for interleukin-15 in T cell migration and activation in rheumatoid arthritis. Nature Medicine. 2:175-182.
24. Elliot, M.J., R.N. Maini, M. Feldmann, J.R. Kalden, C. Antoni, J.S. Smolen, B. Leeb, F.C. Breedveld, J.D. Macfarlane, H. Bijl, and J.N. Woody. 1994. Randomised double blind comparison of a chimaeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis. Lancet. 344:1105-1110.
25. Murrell, G.A.C., D. Jang, and R.J. Williams. 1995. Nitric oxide activates metalloprotease enzymes in articular cartilage. Biochem. Biophys. Res. Commun. 206:15-21.
26. Hauselmann, H.J., L. Oppliger, B.A. Michel, M. Stefanovic-Racic, and C.H. Evans. 1994. Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture. FEBS Lett. 352:361-364.
27. Merryman, P.F., R.M. Clancy, X.Y. He, and S.B. Abramson. 1993. Modulation of human T cell responses by nitric oxide and its derivative S-nitrosoglutathione. Arthr. Rheum. 36:1414-1422.
28. Stefanovic-Racic, M., T.I. Morales, D. Taskiran, L.A. McIntyre, and C.H. Evans. 1996. The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures. J. Immunol. 156:1213-1220.