Treatment with Anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: A randomized, double-blind, placebo-controlled study

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 7, 2011, Pages 2119-2126

  Van Asseldonk, Edwin J P ^a   Stienstra, Rinke ^a   Koenen, Tim B ^a   Joosten, Leo A B ^a   Netea, Mihai G ^a   Tack, Cees J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INSULIN; INTERLEUKIN 1; PLACEBO; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ADIPOSE TISSUE; ADULT; AMBULATORY CARE; ARTICLE; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG WITHDRAWAL; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMAN; HUMAN TISSUE; INFLAMMATION; INFLUENZA A (H1N1); INJECTION SITE REACTION; INSULIN SENSITIVITY; LEUKOCYTE; MACROPHAGE; MALE; METABOLIC SYNDROME X; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADIPOSE TISSUE; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MALE; METABOLIC SYNDROME X; MIDDLE AGED; TREATMENT OUTCOME;

EID: 79960086288     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2010-2992     Document Type: Article

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