-
1
-
-
0033738779
-
Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases
-
Illei GG, Lipsky PE. Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases. Curr Opin Immunol 2000;12:712-8.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 712-718
-
-
Illei, G.G.1
Lipsky, P.E.2
-
2
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 2006;295:2275-85.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
3
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis [review]
-
McInnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis [review]. Nat Rev Immunol 2007;7:429-42.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
4
-
-
0031004174
-
Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production
-
Ghayur T, Banerjee S, Hugunin M, Butler D, Herzog L, Carter A, et al. Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production. Nature 1997;386:619-23.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
-
5
-
-
0031568526
-
IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
-
Kohno K, Kataoka J, Ohtsuki T, Suemoto Y, Okamoto I, Usui M, et al. IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol 1997;158:1541-50.
-
(1997)
J Immunol
, vol.158
, pp. 1541-1550
-
-
Kohno, K.1
Kataoka, J.2
Ohtsuki, T.3
Suemoto, Y.4
Okamoto, I.5
Usui, M.6
-
6
-
-
0030293444
-
IFN-γ-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones
-
Tsutsui H, Nakanishi K, Matsui K, Higashino K, Okamura H, Miyazawa Y, et al. IFN-γ-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J Immunol 1996;157:3967-73.
-
(1996)
J Immunol
, vol.157
, pp. 3967-3973
-
-
Tsutsui, H.1
Nakanishi, K.2
Matsui, K.3
Higashino, K.4
Okamura, H.5
Miyazawa, Y.6
-
7
-
-
0032743708
-
A proinflammatory role for IL-18 in rheumatoid arthritis
-
Gracie JA, Forsey RJ, Chan WL, Gilmour A, Leung BP, Greer MR, et al. A proinflammatory role for IL-18 in rheumatoid arthritis. J Clin Invest 1999;104:1393-401.
-
(1999)
J Clin Invest
, vol.104
, pp. 1393-1401
-
-
Gracie, J.A.1
Forsey, R.J.2
Chan, W.L.3
Gilmour, A.4
Leung, B.P.5
Greer, M.R.6
-
8
-
-
0037080186
-
IL-1β enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): A mechanism for T cell-independent DC activation
-
Luft T, Jefford M, Luetjens P, Hochrein H, Masterman KA, Maliszewski C, et al. IL-1β enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation. J Immunol 2002;168:713-22.
-
(2002)
J Immunol
, vol.168
, pp. 713-722
-
-
Luft, T.1
Jefford, M.2
Luetjens, P.3
Hochrein, H.4
Masterman, K.A.5
Maliszewski, C.6
-
9
-
-
0034872151
-
IL-1β induces dendritic cells to produce IL-12
-
Wesa AK, Galy A. IL-1β induces dendritic cells to produce IL-12. Int Immunol 2001;13:1053-61.
-
(2001)
Int Immunol
, vol.13
, pp. 1053-1061
-
-
Wesa, A.K.1
Galy, A.2
-
10
-
-
0017325645
-
Collagenase production by rheumatoid synovial cells: Stimulation by a human lymphocyte factor
-
Dayer JM, Graham R, Russell G, Krane SM. Collagenase production by rheumatoid synovial cells: stimulation by a human lymphocyte factor. Science 1977;195:181-3.
-
(1977)
Science
, vol.195
, pp. 181-183
-
-
Dayer, J.M.1
Graham, R.2
Russell, G.3
Krane, S.M.4
-
11
-
-
0022472749
-
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
-
Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B, Cerami A, et al. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med 1986;163:1433-50.
-
(1986)
J Exp Med
, vol.163
, pp. 1433-1450
-
-
Dinarello, C.A.1
Cannon, J.G.2
Wolff, S.M.3
Bernheim, H.A.4
Beutler, B.5
Cerami, A.6
-
12
-
-
34547436716
-
TNF-induced structural joint damage is mediated by IL-1
-
Zwerina J, Redlich K, Polzer K, Joosten L, Kronke G, Distler J, et al. TNF-induced structural joint damage is mediated by IL-1. Proc Natl Acad Sci U S A 2007;104:11742-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11742-11747
-
-
Zwerina, J.1
Redlich, K.2
Polzer, K.3
Joosten, L.4
Kronke, G.5
Distler, J.6
-
14
-
-
13444251815
-
Targeting cytokines beyond tumor necrosis factor-α and interleukin-1 in rheumatoid arthritis
-
McInnes IB, Gracie JA. Targeting cytokines beyond tumor necrosis factor-α and interleukin-1 in rheumatoid arthritis. Curr Rheumatol Rep 2004;6:336-42.
-
(2004)
Curr Rheumatol Rep
, vol.6
, pp. 336-342
-
-
McInnes, I.B.1
Gracie, J.A.2
-
15
-
-
0038516689
-
Antibody therapy for rheumatoid arthritis
-
Taylor PC. Antibody therapy for rheumatoid arthritis. Curr Opin Pharmacol 2003;3:323-8.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 323-328
-
-
Taylor, P.C.1
-
16
-
-
4444378185
-
Gene therapy progress and prospects: Downregulating gene expression: the impact of RNA interference [review]
-
Caplen NJ. Gene therapy progress and prospects: downregulating gene expression: the impact of RNA interference [review]. Gene Ther 2004;11:1241-8.
-
(2004)
Gene Ther
, vol.11
, pp. 1241-1248
-
-
Caplen, N.J.1
-
17
-
-
4644336023
-
Revealing the world of RNA interference
-
Mello CC, Conte D Jr. Revealing the world of RNA interference. Nature 2004;431:338-42.
-
(2004)
Nature
, vol.431
, pp. 338-342
-
-
Mello, C.C.1
Conte Jr., D.2
-
18
-
-
24944516000
-
RNA interference and potential therapeutic applications of short interfering RNAs [review]
-
Karagiannis TC, El-Osta A. RNA interference and potential therapeutic applications of short interfering RNAs [review]. Cancer Gene Ther 2005;12:787-95.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 787-795
-
-
Karagiannis, T.C.1
El-Osta, A.2
-
19
-
-
25144444898
-
Electro-transfer of small interfering RNA ameliorated arthritis in rats
-
Inoue A, Takahashi KA, Mazda O, Terauchi R, Arai Y, Kishida T, et al. Electro-transfer of small interfering RNA ameliorated arthritis in rats. Biochem Biophys Res Commun 2005;336:903-8.
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 903-908
-
-
Inoue, A.1
Takahashi, K.A.2
Mazda, O.3
Terauchi, R.4
Arai, Y.5
Kishida, T.6
-
20
-
-
17244378648
-
Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis
-
Schiffelers RM, Xu J, Storm G, Woodle MC, Scaria PV. Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis. Arthritis Rheum 2005;52: 1314-8.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1314-1318
-
-
Schiffelers, R.M.1
Xu, J.2
Storm, G.3
Woodle, M.C.4
Scaria, P.V.5
-
21
-
-
33745014998
-
Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis
-
Khoury M, Louis-Plence P, Escriou V, Noel D, Largeau C, Cantos C, et al. Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis. Arthritis Rheum 2006;54:1867-77.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1867-1877
-
-
Khoury, M.1
Louis-Plence, P.2
Escriou, V.3
Noel, D.4
Largeau, C.5
Cantos, C.6
-
22
-
-
0032518063
-
Synthesis, activity, and structure - activity relationship studies of novel cationic lipids for DNA transfer
-
Byk G, Dubertret C, Escriou V, Frederic M, Jaslin G, Rangara R, et al. Synthesis, activity, and structure - activity relationship studies of novel cationic lipids for DNA transfer. J Med Chem 1998;41:229-35.
-
(1998)
J Med Chem
, vol.41
, pp. 229-235
-
-
Byk, G.1
Dubertret, C.2
Escriou, V.3
Frederic, M.4
Jaslin, G.5
Rangara, R.6
-
23
-
-
0347264779
-
Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: Application to interleukin 10 therapy in experimental arthritis
-
Perez N, Plence P, Millet V, Greuet D, Minot C, Noel D, et al. Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis. Hum Gene Ther 2002;13:2161-72.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 2161-2172
-
-
Perez, N.1
Plence, P.2
Millet, V.3
Greuet, D.4
Minot, C.5
Noel, D.6
-
24
-
-
18644370435
-
Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor α in collagen-induced arthritis
-
Djouad F, Fritz V, Apparailly F, Louis-Plence P, Bony C, Sany J, et al. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor α in collagen-induced arthritis. Arthritis Rheum 2005;52:1595-603.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1595-1603
-
-
Djouad, F.1
Fritz, V.2
Apparailly, F.3
Louis-Plence, P.4
Bony, C.5
Sany, J.6
-
25
-
-
0041622790
-
RNA interference shows critical requirement for NF-κB p50 in the production of IL-12 by human dendritic cells
-
Laderach D, Compagno D, Danos O, Vainchenker W, Galy A. RNA interference shows critical requirement for NF-κB p50 in the production of IL-12 by human dendritic cells. J Immunol 2003; 171:1750-7.
-
(2003)
J Immunol
, vol.171
, pp. 1750-1757
-
-
Laderach, D.1
Compagno, D.2
Danos, O.3
Vainchenker, W.4
Galy, A.5
-
26
-
-
0032102995
-
Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis
-
Apparailly F, Verwaerde C, Jacquet C, Auriault C, Sany J, Jorgensen C. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. J Immunol 1998;160: 5213-20.
-
(1998)
J Immunol
, vol.160
, pp. 5213-5220
-
-
Apparailly, F.1
Verwaerde, C.2
Jacquet, C.3
Auriault, C.4
Sany, J.5
Jorgensen, C.6
-
27
-
-
0033041866
-
Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis
-
Butler DM, Malfait AM, Maini RN, Brennan FM, Feldmann M. Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis. Eur J Immunol 1999;29:2205-12.
-
(1999)
Eur J Immunol
, vol.29
, pp. 2205-2212
-
-
Butler, D.M.1
Malfait, A.M.2
Maini, R.N.3
Brennan, F.M.4
Feldmann, M.5
-
28
-
-
0032169765
-
Different roles of tumour necrosis factor α and interleukin 1 in murine streptococcal cell wall arthritis
-
Kuiper S, Joosten LA, Bendele AM, Edwards CK III, Arntz OJ, Helsen MM, et al. Different roles of tumour necrosis factor α and interleukin 1 in murine streptococcal cell wall arthritis. Cytokine 1998;10:690-702.
-
(1998)
Cytokine
, vol.10
, pp. 690-702
-
-
Kuiper, S.1
Joosten, L.A.2
Bendele, A.M.3
Edwards III, C.K.4
Arntz, O.J.5
Helsen, M.M.6
-
30
-
-
0033764203
-
Arguments for interleukin 1 as a target in chronic arthritis
-
Van den Berg WB. Arguments for interleukin 1 as a target in chronic arthritis. Ann Rheum Dis 2000;59 Suppl 1:i81-4.
-
(2000)
Ann Rheum Dis
, Issue.SUPPL. 1
, pp. 59
-
-
Van den Berg, W.B.1
-
32
-
-
33644964894
-
Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells
-
Hoeve MA, Savage ND, de Boer T, Langenberg DM, de Waal Malefyt R, Ottenhoff TH, et al. Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells. Eur J Immunol 2006;36:661-70.
-
(2006)
Eur J Immunol
, vol.36
, pp. 661-670
-
-
Hoeve, M.A.1
Savage, N.D.2
de Boer, T.3
Langenberg, D.M.4
de Waal Malefyt, R.5
Ottenhoff, T.H.6
-
33
-
-
11844262129
-
Delivery of siRNA and siRNA expression constructs to adult mammals by hydrodynamic intravascular injection
-
Lewis DL, Wolff JA. Delivery of siRNA and siRNA expression constructs to adult mammals by hydrodynamic intravascular injection. Methods Enzymol 2005;392:336-50.
-
(2005)
Methods Enzymol
, vol.392
, pp. 336-350
-
-
Lewis, D.L.1
Wolff, J.A.2
-
34
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 2005;23:1002-7.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
-
35
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003;9:347-51.
-
(2003)
Nat Med
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
Ince, N.4
Ouyang, N.5
Min, J.6
-
36
-
-
33747865175
-
Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice
-
Khazanov E, Simberg D, Barenholz Y. Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice. J Gene Med 2006;8:998-1007.
-
(2006)
J Gene Med
, vol.8
, pp. 998-1007
-
-
Khazanov, E.1
Simberg, D.2
Barenholz, Y.3
-
37
-
-
33746883220
-
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium
-
Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, et al. A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther 2006;13:1222-34.
-
(2006)
Gene Ther
, vol.13
, pp. 1222-1234
-
-
Santel, A.1
Aleku, M.2
Keil, O.3
Endruschat, J.4
Esche, V.5
Fisch, G.6
-
38
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen DR, Leirdal M, Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 2003;327: 761-6.
-
(2003)
J Mol Biol
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
39
-
-
9344224580
-
Antitumor activity of small interfering RNA/ cationic liposome complex in mouse models of cancer
-
Yano J, Hirabayashi K, Nakagawa S, Yamaguchi T, Nogawa M, Kashimori I, et al. Antitumor activity of small interfering RNA/ cationic liposome complex in mouse models of cancer. Clin Cancer Res 2004;10:7721-6.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7721-7726
-
-
Yano, J.1
Hirabayashi, K.2
Nakagawa, S.3
Yamaguchi, T.4
Nogawa, M.5
Kashimori, I.6
-
40
-
-
0032545793
-
Cationic lipid-mediated gene transfer: Effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes
-
Escriou V, Ciolina C, Lacroix F, Byk G, Scherman D, Wils P. Cationic lipid-mediated gene transfer: effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes. Biochim Biophys Acta 1998;1368:276-88.
-
(1998)
Biochim Biophys Acta
, vol.1368
, pp. 276-288
-
-
Escriou, V.1
Ciolina, C.2
Lacroix, F.3
Byk, G.4
Scherman, D.5
Wils, P.6
|