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Volumn 10, Issue 9, 2014, Pages 1863-1893

Pulmonary multifunctional nano-oncological modules for lung cancer treatment and prevention

Author keywords

Lung cancer; Metastasis; Nano Oncological modules; Nanoparticles; Pulmonary delivery

Indexed keywords

CELL MEMBRANES; CYTOLOGY; DISEASES; ENZYME ACTIVITY; NANOPARTICLES; PATHOLOGY;

EID: 84904858553     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1900     Document Type: Review
Times cited : (5)

References (276)
  • 1
    • 0035065024 scopus 로고    scopus 로고
    • Pulmonary preinvasive neoplasia
    • K. M. Kerr, Pulmonary preinvasive neoplasia. J. Clin. Pathol. 54, 257 (2001).
    • (2001) J. Clin. Pathol. , vol.54 , pp. 257
    • Kerr, K.M.1
  • 4
    • 33845906339 scopus 로고    scopus 로고
    • Inhaling medicines: Delivering drugs to the body through the lungs
    • J. S. Patton and P. R. Byron, Inhaling medicines: Delivering drugs to the body through the lungs. Nat. Rev. Drug Discov. 6, 67 (2007).
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 67
    • Patton, J.S.1    Byron, P.R.2
  • 5
    • 0036401287 scopus 로고    scopus 로고
    • Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung
    • J. Hukkanen, O. Pelkonen, J. Hakkola, and H. Raunio, Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung. Crit. Rev. Toxicol. 32, 391 (2002).
    • (2002) Crit. Rev. Toxicol. , vol.32 , pp. 391
    • Hukkanen, J.1    Pelkonen, O.2    Hakkola, J.3    Raunio, H.4
  • 6
    • 77955440267 scopus 로고    scopus 로고
    • Update on macrophage clearance of inhaled micro- and nanoparticles
    • M. Geiser, Update on macrophage clearance of inhaled micro- and nanoparticles. J. Aerosol Med. Pulm. Drug Deliv. 23, 207 (2010).
    • (2010) J. Aerosol Med. Pulm. Drug Deliv. , vol.23 , pp. 207
    • Geiser, M.1
  • 8
    • 84859735921 scopus 로고    scopus 로고
    • Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery - A review for multidisciplinary researchers
    • N. Islam and M. J. Cleary, Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery - a review for multidisciplinary researchers. Med. Eng. Phys. 34, 409 (2012).
    • (2012) Med. Eng. Phys. , vol.34 , pp. 409
    • Islam, N.1    Cleary, M.J.2
  • 9
    • 84893816004 scopus 로고    scopus 로고
    • Endosomal escape: A bottleneck in intracellular delivery
    • H. Shete, R. Prabhu, and V. Patravale, Endosomal escape: A bottleneck in intracellular delivery. J. Nanosci. Nanotechnol. 14, 460 (2013).
    • (2013) J. Nanosci. Nanotechnol. , vol.14 , pp. 460
    • Shete, H.1    Prabhu, R.2    Patravale, V.3
  • 11
    • 84880533771 scopus 로고    scopus 로고
    • Lipid colloidal carriers for improvement of anticancer activity of orally delivered quercetin: Formulation, characterization and establishing in vitro-in vivo advantage
    • A. S. Jain, S. M. Shah, M. S. Nagarsenker, Y. Nikam, R. P. Gude, F. Steiniger, J. Thamm, and A. Fahr, Lipid colloidal carriers for improvement of anticancer activity of orally delivered quercetin: Formulation, characterization and establishing in vitro-in vivo advantage. J. Biomed. Nanotechnol. 9, 1230 (2013).
    • (2013) J. Biomed. Nanotechnol. , vol.9 , pp. 1230
    • Jain, A.S.1    Shah, S.M.2    Nagarsenker, M.S.3    Nikam, Y.4    Gude, R.P.5    Steiniger, F.6    Thamm, J.7    Fahr, A.8
  • 13
    • 84877836975 scopus 로고    scopus 로고
    • Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles
    • D. Wehrung, L. Bi, W. J. Geldenhuys, and M. O. Oyewumi, Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles. J. Biomed. Nanotechnol. 9, 1029 (2013).
    • (2013) J. Biomed. Nanotechnol. , vol.9 , pp. 1029
    • Wehrung, D.1    Bi, L.2    Geldenhuys, W.J.3    Oyewumi, M.O.4
  • 14
    • 84859160978 scopus 로고    scopus 로고
    • Antitumor effect of novel gallium compounds and efficacy of nanoparticle-mediated gallium delivery in lung cancer
    • D. Wehrung and M. O. Oyewumi, Antitumor effect of novel gallium compounds and efficacy of nanoparticle-mediated gallium delivery in lung cancer. J. Biomed. Nanotechnol. 8, 161 (2012).
    • (2012) J. Biomed. Nanotechnol. , vol.8 , pp. 161
    • Wehrung, D.1    Oyewumi, M.O.2
  • 15
    • 84857096093 scopus 로고    scopus 로고
    • Enhancement of cancer chemosensitization potential of cisplatin by tea polyphenols poly(lactide-co-glycolide) nanoparticles
    • M. Singh, P. Bhatnagar, A. K. Srivastava, P. Kumar, Y. Shukla, and K. C. Gupta, Enhancement of cancer chemosensitization potential of cisplatin by tea polyphenols poly(lactide-co-glycolide) nanoparticles. J. Biomed. Nanotechnol. 7, 202 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 202
    • Singh, M.1    Bhatnagar, P.2    Srivastava, A.K.3    Kumar, P.4    Shukla, Y.5    Gupta, K.C.6
  • 16
    • 84895022848 scopus 로고    scopus 로고
    • Selective eradication of tumor vascular pericytes by peptide-conjugated nanoparticles for antiangiogenic therapy of melanoma lung metastasis
    • Y. Y. Guan, X. Luan, J. R. Xu, Y. R. Liu, Q. Lu, C. Wang, H. J. Liu, Y. G. Gao, H. Z. Chen, and C. Fang, Selective eradication of tumor vascular pericytes by peptide-conjugated nanoparticles for antiangiogenic therapy of melanoma lung metastasis. Biomaterials 35, 3060 (2014).
    • (2014) Biomaterials , vol.35 , pp. 3060
    • Guan, Y.Y.1    Luan, X.2    Xu, J.R.3    Liu, Y.R.4    Lu, Q.5    Wang, C.6    Liu, H.J.7    Gao, Y.G.8    Chen, H.Z.9    Fang, C.10
  • 17
    • 84884306434 scopus 로고    scopus 로고
    • Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models
    • C. Godugu, A. R. Patel, R. Doddapaneni, S. Marepally, T. Jackson, and M. Singh, Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models. J. Control. Release. 172, 86 (2013).
    • (2013) J. Control. Release. , vol.172 , pp. 86
    • Godugu, C.1    Patel, A.R.2    Doddapaneni, R.3    Marepally, S.4    Jackson, T.5    Singh, M.6
  • 18
    • 84866515787 scopus 로고    scopus 로고
    • Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect
    • M. Videira, A. J. Almeida, and A. Fabra, Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect. Nanomedicine 8, 1208 (2012).
    • (2012) Nanomedicine , vol.8 , pp. 1208
    • Videira, M.1    Almeida, A.J.2    Fabra, A.3
  • 19
    • 81255143432 scopus 로고    scopus 로고
    • Innovative strategy for treatment of lung cancer: Targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA
    • O. Taratula, O. B. Garbuzenko, A. M. Chen, and T. Minko, Innovative strategy for treatment of lung cancer: Targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA. J. Drug Target 19, 900 (2011).
    • (2011) J. Drug Target , vol.19 , pp. 900
    • Taratula, O.1    Garbuzenko, O.B.2    Chen, A.M.3    Minko, T.4
  • 20
  • 21
    • 23744472983 scopus 로고    scopus 로고
    • Gene expression perturbation in vitro - A growing case for three-dimensional (3D) culture systems
    • A. Birgersdotter, R. Sandberg, and I. Ernberg, Gene expression perturbation in vitro - a growing case for three-dimensional (3D) culture systems. Semin. Cancer Biol. 15, 405 (2005).
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 405
    • Birgersdotter, A.1    Sandberg, R.2    Ernberg, I.3
  • 23
    • 33748967069 scopus 로고    scopus 로고
    • Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer
    • C. M. Nelson and M. J. Bissell, Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 22, 287 (2006).
    • (2006) Annu. Rev. Cell Dev. Biol. , vol.22 , pp. 287
    • Nelson, C.M.1    Bissell, M.J.2
  • 24
    • 84866456094 scopus 로고    scopus 로고
    • Human lung cancer cells grown in an ex vivo 3D lung model produce matrix metalloproteinases not produced in 2D culture
    • D. K. Mishra, J. H. Sakamoto, M. J. Thrall, B. N. Baird, S. H. Blackmon, M. Ferrari, J. M. Kurie, and M. P. Kim, Human lung cancer cells grown in an ex vivo 3D lung model produce matrix metalloproteinases not produced in 2D culture. PLoS One 7, 17 (2012).
    • (2012) PLoS One , vol.7 , pp. 17
    • Mishra, D.K.1    Sakamoto, J.H.2    Thrall, M.J.3    Baird, B.N.4    Blackmon, S.H.5    Ferrari, M.6    Kurie, J.M.7    Kim, M.P.8
  • 25
    • 0035313918 scopus 로고    scopus 로고
    • Methods used to assess pulmonary deposition and absorption of drugs
    • C. Mobley and G. Hochhaus, Methods used to assess pulmonary deposition and absorption of drugs. Drug Discov. Today 6, 367 (2001).
    • (2001) Drug Discov. Today , vol.6 , pp. 367
    • Mobley, C.1    Hochhaus, G.2
  • 26
    • 33750845387 scopus 로고    scopus 로고
    • In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery
    • M. Sakagami, In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery. Adv. Drug Deliv. Rev. 58, 1030 (2006).
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1030
    • Sakagami, M.1
  • 27
    • 75349108981 scopus 로고    scopus 로고
    • Preclinical models for pulmonary drug delivery
    • C. A. Fernandes and R. Vanbever, Preclinical models for pulmonary drug delivery. Expert Opin. Drug Deliv. 6, 1231 (2009).
    • (2009) Expert Opin. Drug Deliv. , vol.6 , pp. 1231
    • Fernandes, C.A.1    Vanbever, R.2
  • 28
    • 78650545991 scopus 로고    scopus 로고
    • In vitro and in vivo testing methods for respiratory drug delivery
    • R. U. Agu and M. I. Ugwoke, In vitro and in vivo testing methods for respiratory drug delivery. Expert Opin. Drug Deliv. 8, 57 (2011).
    • (2011) Expert Opin. Drug Deliv. , vol.8 , pp. 57
    • Agu, R.U.1    Ugwoke, M.I.2
  • 29
    • 35448952967 scopus 로고    scopus 로고
    • In vivo animal models for drug delivery across the lung mucosal barrier
    • S. A. Cryan, N. Sivadas, and L. Garcia-Contreras, In vivo animal models for drug delivery across the lung mucosal barrier. Adv. Drug Deliv. Rev. 59, 1133 (2007).
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1133
    • Cryan, S.A.1    Sivadas, N.2    Garcia-Contreras, L.3
  • 30
    • 84880540526 scopus 로고    scopus 로고
    • Multifunctional phosphine stabilized gold nanoparticles: An active catalytic system for three-component coupling reaction
    • B. J. Borah, S. J. Borah, and D. K. Dutta, Multifunctional phosphine stabilized gold nanoparticles: An active catalytic system for three-component coupling reaction. J. Nanosci. Nanotechnol. 13, 5080 (2013).
    • (2013) J. Nanosci. Nanotechnol. , vol.13 , pp. 5080
    • Borah, B.J.1    Borah, S.J.2    Dutta, D.K.3
  • 31
    • 84865319006 scopus 로고    scopus 로고
    • Engineered multifunctional RGD-gold nanoparticles for the detection of tumour-specific alpha(v)beta(3) expression: Chemical characterisation and ecotoxicological risk assessment
    • E. Morales-Avila, G. Ferro-Flores, B. E. Ocampo-García, and L. M. Gómez-Oliván, Engineered multifunctional RGD-gold nanoparticles for the detection of tumour-specific alpha(v)beta(3) expression: Chemical characterisation and ecotoxicological risk assessment. J. Biomed. Nanotechnol. 8, 991 (2012).
    • (2012) J. Biomed. Nanotechnol. , vol.8 , pp. 991
    • Morales-Avila, E.1    Ferro-Flores, G.2    Ocampo-García, B.E.3    Gómez-Oliván, L.M.4
  • 32
    • 79952111870 scopus 로고    scopus 로고
    • Multifunctional nanoparticles for targeting cancer therapy
    • Z. G. Gao, Z. H. Jin, X. Z. Yin, and L. Tian, Multifunctional nanoparticles for targeting cancer therapy. J. Nanosci. Nanotechnol. 10, 7743 (2010).
    • (2010) J. Nanosci. Nanotechnol. , vol.10 , pp. 7743
    • Gao, Z.G.1    Jin, Z.H.2    Yin, X.Z.3    Tian, L.4
  • 33
    • 84880870227 scopus 로고    scopus 로고
    • Novel multifunctional biocompatible gelatin-oleic acid conjugate: Self-assembled nanoparticles for drug delivery
    • P. H. Tran, T. T. Tran, T. V. Vo, C. L. Vo, and B. J. Lee, Novel multifunctional biocompatible gelatin-oleic acid conjugate: Self-assembled nanoparticles for drug delivery. J. Biomed. Nanotechnol. 9, 1416 (2013).
    • (2013) J. Biomed. Nanotechnol. , vol.9 , pp. 1416
    • Tran, P.H.1    Tran, T.T.2    Vo, T.V.3    Vo, C.L.4    Lee, B.J.5
  • 34
    • 0027215460 scopus 로고
    • Nasal distribution of budesonide inhaled via a powder inhaler
    • L. Thorsson, S. P. Newman, A. Weisz, E. Trofast, and F. Moren, Nasal distribution of budesonide inhaled via a powder inhaler. Rhinology 31, 7 (1993).
    • (1993) Rhinology , vol.31 , pp. 7
    • Thorsson, L.1    Newman, S.P.2    Weisz, A.3    Trofast, E.4    Moren, F.5
  • 36
    • 70350352914 scopus 로고    scopus 로고
    • Epithelium, cilia, and mucus: Their importance in chronic rhinosinusitis
    • M. B. Antunes, D. A. Gudis, and N. A. Cohen, Epithelium, cilia, and mucus: Their importance in chronic rhinosinusitis. Immunol. Allergy Clin. North Am. 29, 631 (2009).
    • (2009) Immunol. Allergy Clin. North Am. , vol.29 , pp. 631
    • Antunes, M.B.1    Gudis, D.A.2    Cohen, N.A.3
  • 37
    • 70149122456 scopus 로고    scopus 로고
    • Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesium
    • J. Rosenecker, S. Naundorf, and C. Rudolph, Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesium. Eur. J. Med. Res. 14, 304 (2009).
    • (2009) Eur. J. Med. Res. , vol.14 , pp. 304
    • Rosenecker, J.1    Naundorf, S.2    Rudolph, C.3
  • 38
    • 50949083025 scopus 로고    scopus 로고
    • Structure of pulmonary surfactant membranes and films: The role of proteins and lipid-protein interactions
    • J. Perez-Gil, Structure of pulmonary surfactant membranes and films: The role of proteins and lipid-protein interactions. Biochim. Biophys. Acta 1778, 1676 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 1676
    • Perez-Gil, J.1
  • 41
    • 36348985545 scopus 로고    scopus 로고
    • Functional imaging of mucociliary phenomena: High-speed digital reflection contrast microscopy
    • M. Ryser, A. Burn, T. Wessel, M. Frenz, and J. Ricka, Functional imaging of mucociliary phenomena: High-speed digital reflection contrast microscopy. Eur. Biophys. J. 37, 35 (2007).
    • (2007) Eur. Biophys. J. , vol.37 , pp. 35
    • Ryser, M.1    Burn, A.2    Wessel, T.3    Frenz, M.4    Ricka, J.5
  • 43
    • 84876361438 scopus 로고    scopus 로고
    • Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections
    • M. Guilliams, B. N. Lambrecht, and H. Hammad, Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections. Mucosal Immunol. 6, 464 (2013).
    • (2013) Mucosal Immunol. , vol.6 , pp. 464
    • Guilliams, M.1    Lambrecht, B.N.2    Hammad, H.3
  • 44
    • 84881487990 scopus 로고    scopus 로고
    • Mechanisms of absorption and elimination of drugs administered by inhalation
    • M. Ibrahim and L. Garcia-Contreras, Mechanisms of absorption and elimination of drugs administered by inhalation. Therapeutic Deliv. 4, 1027 (2013).
    • (2013) Therapeutic Deliv. , vol.4 , pp. 1027
    • Ibrahim, M.1    Garcia-Contreras, L.2
  • 45
    • 0037216616 scopus 로고    scopus 로고
    • Classification, staging and prognosis of lung cancer
    • C. J. Beadsmoore and N. J. Screaton, Classification, staging and prognosis of lung cancer. Eur. J. Radiol. 45, 8 (2003).
    • (2003) Eur. J. Radiol. , vol.45 , pp. 8
    • Beadsmoore, C.J.1    Screaton, N.J.2
  • 46
    • 0023726197 scopus 로고
    • Prognosis and survival in resected lung carcinoma based on the new international staging system
    • T. Naruke, T. Goya, R. Tsuchiya, and K. Suemasu, Prognosis and survival in resected lung carcinoma based on the new international staging system. J. Thorac. Cardiovasc. Surg. 96, 440 (1988).
    • (1988) J. Thorac. Cardiovasc. Surg. , vol.96 , pp. 440
    • Naruke, T.1    Goya, T.2    Tsuchiya, R.3    Suemasu, K.4
  • 47
    • 85104568580 scopus 로고    scopus 로고
    • A new international staging system for lung cancer. 1986
    • C. F. Mountain, A new international staging system for lung cancer. 1986. Chest 136, e25 (2009).
    • (2009) Chest , vol.136
    • Mountain, C.F.1
  • 48
    • 84880562947 scopus 로고    scopus 로고
    • Aerosol delivery to intubated patients
    • J. Fink and A. Ari, Aerosol delivery to intubated patients. Expert Opin. Drug Deliv. 10, 1077 (2013).
    • (2013) Expert Opin. Drug Deliv. , vol.10 , pp. 1077
    • Fink, J.1    Ari, A.2
  • 51
    • 0031454495 scopus 로고    scopus 로고
    • Pulmonary drug delivery: Physiologic and mechanistic aspects
    • J. Yu and Y. W. Chien, Pulmonary drug delivery: Physiologic and mechanistic aspects. Crit. Rev. Ther. Drug Carrier Syst. 14, 395 (1997).
    • (1997) Crit. Rev. Ther. Drug Carrier Syst. , vol.14 , pp. 395
    • Yu, J.1    Chien, Y.W.2
  • 52
    • 33644840116 scopus 로고    scopus 로고
    • Inhaled insulin is approved in Europe and United States
    • J. Lenzer, Inhaled insulin is approved in Europe and United States. BMJ 332, 321 (2006).
    • (2006) BMJ , vol.332 , pp. 321
    • Lenzer, J.1
  • 53
    • 84855572796 scopus 로고    scopus 로고
    • New ways of insulin delivery
    • L. Heinemann, New ways of insulin delivery. Int J Clin Pract Suppl. 170, 31 (2011).
    • (2011) Int J Clin Pract Suppl. , vol.170 , pp. 31
    • Heinemann, L.1
  • 55
    • 84861116554 scopus 로고    scopus 로고
    • Nebulized anticoagulants for acute lung injury - A systematic review of preclinical and clinical investigations
    • P. R. Tuinman, B. Dixon, M. Levi, N. P. Juffermans, and M. J. Schultz, Nebulized anticoagulants for acute lung injury - A systematic review of preclinical and clinical investigations. Crit. Care 16, R70 (2012).
    • (2012) Crit. Care , vol.16
    • Tuinman, P.R.1    Dixon, B.2    Levi, M.3    Juffermans, N.P.4    Schultz, M.J.5
  • 56
    • 77955984808 scopus 로고    scopus 로고
    • Treatment of systemic diseases by inhalation of biomolecule aerosols
    • R. Siekmeier and G. Scheuch, Treatment of systemic diseases by inhalation of biomolecule aerosols. J. Physiol. Pharmacol. 5, 15 (2009).
    • (2009) J. Physiol. Pharmacol. , vol.5 , pp. 15
    • Siekmeier, R.1    Scheuch, G.2
  • 57
    • 79957692320 scopus 로고    scopus 로고
    • Formation, characterization, and fate of inhaled drug nanoparticles
    • J. Zhang, L. Wu, H. K. Chan, and W. Watanabe, Formation, characterization, and fate of inhaled drug nanoparticles. Adv. Drug Deliv. Rev. 63, 441 (2011).
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 441
    • Zhang, J.1    Wu, L.2    Chan, H.K.3    Watanabe, W.4
  • 58
    • 84857356334 scopus 로고    scopus 로고
    • Propellant-based inhalers for the non-invasive delivery of genes via oral inhalation
    • D. S. Conti, B. Bharatwaj, D. Brewer, and S. R. da Rocha, Propellant-based inhalers for the non-invasive delivery of genes via oral inhalation. J. Control. Release 157, 406 (2012).
    • (2012) J. Control. Release , vol.157 , pp. 406
    • Conti, D.S.1    Bharatwaj, B.2    Brewer, D.3    Da Rocha, S.R.4
  • 59
    • 33644748125 scopus 로고    scopus 로고
    • Anticancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549
    • S. V. Fulzele, M. S. Shaik, A. Chatterjee, and M. Singh, Anticancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549. J. Pharm. Pharmacol. 58, 327 (2006).
    • (2006) J. Pharm. Pharmacol. , vol.58 , pp. 327
    • Fulzele, S.V.1    Shaik, M.S.2    Chatterjee, A.3    Singh, M.4
  • 60
    • 33644617924 scopus 로고    scopus 로고
    • Dry powder inhaler formulation
    • M. J. Telko and A. J. Hickey, Dry powder inhaler formulation. Respir. Care 50, 1209 (2005).
    • (2005) Respir. Care , vol.50 , pp. 1209
    • Telko, M.J.1    Hickey, A.J.2
  • 62
    • 0034791636 scopus 로고    scopus 로고
    • Immunological and toxicological implications of short-term studies in animals of pharmaceutical aerosol delivery to the lungs: Relevance to humans
    • A. J. Hickey and L. Garcia-Contreras, Immunological and toxicological implications of short-term studies in animals of pharmaceutical aerosol delivery to the lungs: Relevance to humans. Crit. Rev. Ther. Drug Carrier Syst. 18, 387 (2001).
    • (2001) Crit. Rev. Ther. Drug Carrier Syst. , vol.18 , pp. 387
    • Hickey, A.J.1    Garcia-Contreras, L.2
  • 64
    • 84879470777 scopus 로고    scopus 로고
    • Characterization and aerosol dispersion performance of advanced spray-dried chemotherapeutic PEGylated phospholipid particles for dry powder inhalation delivery in lung cancer
    • S. A. Meenach, K. W. Anderson, J. Zach Hilt, R. C. McGarry, and H. M. Mansour, Characterization and aerosol dispersion performance of advanced spray-dried chemotherapeutic PEGylated phospholipid particles for dry powder inhalation delivery in lung cancer. Eur. J. Pharm. Sci. 49, 699 (2013).
    • (2013) Eur. J. Pharm. Sci. , vol.49 , pp. 699
    • Meenach, S.A.1    Anderson, K.W.2    Zach Hilt, J.3    McGarry, R.C.4    Mansour, H.M.5
  • 65
    • 77952670572 scopus 로고    scopus 로고
    • Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation
    • K. Mohri, T. Okuda, A. Mori, K. Danjo, and H. Okamoto, Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation. J. Control Release 144, 221 (2010).
    • (2010) J. Control Release , vol.144 , pp. 221
    • Mohri, K.1    Okuda, T.2    Mori, A.3    Danjo, K.4    Okamoto, H.5
  • 67
    • 84892675615 scopus 로고    scopus 로고
    • Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA
    • O. Taratula, A. Kuzmov, M. Shah, O. B. Garbuzenko, and T. Minko, Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA. J. Control Release 171, 349 (2013).
    • (2013) J. Control Release , vol.171 , pp. 349
    • Taratula, O.1    Kuzmov, A.2    Shah, M.3    Garbuzenko, O.B.4    Minko, T.5
  • 68
    • 84904259316 scopus 로고    scopus 로고
    • Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids
    • W. Liang, P. C. Kwok, M. Y. Chow, P. Tang, A. J. Mason, H. K. Chan, and J. K. Lam, Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids. Eur. J. Pharm. Biopharm. 20, 00174 (2013).
    • (2013) Eur. J. Pharm. Biopharm. , vol.20 , pp. 00174
    • Liang, W.1    Kwok, P.C.2    Chow, M.Y.3    Tang, P.4    Mason, A.J.5    Chan, H.K.6    Lam, J.K.7
  • 69
    • 84864711649 scopus 로고    scopus 로고
    • An inhalable beta(2)-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung
    • Y. Luo, X. Zhai, C. Ma, P. Sun, Z. Fu, W. Liu, and J. Xu, An inhalable beta(2)-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung. J. Control Release 162, 28 (2012).
    • (2012) J. Control Release , vol.162 , pp. 28
    • Luo, Y.1    Zhai, X.2    Ma, C.3    Sun, P.4    Fu, Z.5    Liu, W.6    Xu, J.7
  • 71
    • 81155154255 scopus 로고    scopus 로고
    • In vivo transfection study of chitosan-DNA-FAP-B nanoparticles as a new non viral vector for gene delivery to the lung
    • Z. Mohammadi, F. A. Dorkoosh, S. Hosseinkhani, K. Gilani, T. Amini, A. R. Najafabadi, and M. R. Tehrani, In vivo transfection study of chitosan-DNA-FAP-B nanoparticles as a new non viral vector for gene delivery to the lung. Int. J. Pharm. 421, 183 (2011).
    • (2011) Int. J. Pharm. , vol.421 , pp. 183
    • Mohammadi, Z.1    Dorkoosh, F.A.2    Hosseinkhani, S.3    Gilani, K.4    Amini, T.5    Najafabadi, A.R.6    Tehrani, M.R.7
  • 76
    • 0036835672 scopus 로고    scopus 로고
    • Design principles of liquid nebulization devices currently in use
    • J. L. Rau, Design principles of liquid nebulization devices currently in use. Respir. Care. 47, 1257 (2002).
    • (2002) Respir. Care. , vol.47 , pp. 1257
    • Rau, J.L.1
  • 77
    • 0029586446 scopus 로고
    • Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers
    • O. N. McCallion, K. M. Taylor, M. Thomas, and A. J. Taylor, Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers. Pharm. Res. 12, 1682 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 1682
    • McCallion, O.N.1    Taylor, K.M.2    Thomas, M.3    Taylor, A.J.4
  • 78
    • 0036885621 scopus 로고    scopus 로고
    • Nebulizers that use a vibrating mesh or plate with multiple apertures to generate aerosol
    • R. Dhand, Nebulizers that use a vibrating mesh or plate with multiple apertures to generate aerosol. Respir. Care. 47, 1406 (2002).
    • (2002) Respir. Care. , vol.47 , pp. 1406
    • Dhand, R.1
  • 79
    • 77954482813 scopus 로고    scopus 로고
    • Performance of PARI eFlow
    • author reply 114
    • A. L. Coates, Performance of PARI eFlow. J. Aerosol Med. Pulm. Drug Deliv. 23, 114; author reply 114 (2010).
    • (2010) J. Aerosol Med. Pulm. Drug Deliv. , vol.23 , pp. 114
    • Coates, A.L.1
  • 82
    • 0021337761 scopus 로고
    • Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone
    • W. L. Eschenbacher, H. A. Boushey, and D. Sheppard, Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone. Am. Rev. Respir. Dis. 129, 211 (1984).
    • (1984) Am. Rev. Respir. Dis. , vol.129 , pp. 211
    • Eschenbacher, W.L.1    Boushey, H.A.2    Sheppard, D.3
  • 83
    • 0033618483 scopus 로고    scopus 로고
    • A new approach to modelling the relationship between in vitro and in vivo drug dissolution/ absorption
    • A. Dunne, T. O'Hara, and J. Devane, A new approach to modelling the relationship between in vitro and in vivo drug dissolution/ absorption. Stat. Med. 18, 1865 (1999).
    • (1999) Stat. Med. , vol.18 , pp. 1865
    • Dunne, A.1    O'Hara, T.2    Devane, J.3
  • 84
    • 0032879891 scopus 로고    scopus 로고
    • Optimizing the in vitro performance of Respimat
    • B. Zierenberg, Optimizing the in vitro performance of Respimat. J. Aerosol Med. 12, S19 (1999).
    • (1999) J. Aerosol Med. , vol.12
    • Zierenberg, B.1
  • 85
    • 0029757981 scopus 로고    scopus 로고
    • Efficient delivery to the lungs of flunisolide aerosol from a new portable hand-held multidose nebulizer
    • S. P. Newman, K. P. Steed, S. J. Reader, G. Hooper, and B. Zierenberg, Efficient delivery to the lungs of flunisolide aerosol from a new portable hand-held multidose nebulizer. J. Pharm. Sci. 85, 960 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 960
    • Newman, S.P.1    Steed, K.P.2    Reader, S.J.3    Hooper, G.4    Zierenberg, B.5
  • 86
    • 0031977041 scopus 로고    scopus 로고
    • Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: Comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices
    • S. P. Newman, J. Brown, K. P. Steed, S. J. Reader, and H. Kladders, Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: Comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices. Chest. 113, 957 (1998).
    • (1998) Chest. , vol.113 , pp. 957
    • Newman, S.P.1    Brown, J.2    Steed, K.P.3    Reader, S.J.4    Kladders, H.5
  • 88
    • 0032969698 scopus 로고    scopus 로고
    • Intranasal insulin delivery and therapy
    • M. Hinchcliffe and L. Illum, Intranasal insulin delivery and therapy. Adv. Drug Deliv. Rev. 35, 199 (1999).
    • (1999) Adv. Drug Deliv. Rev. , vol.35 , pp. 199
    • Hinchcliffe, M.1    Illum, L.2
  • 92
    • 79955652343 scopus 로고    scopus 로고
    • Intranasal delivery of whole cell lysate of Mycobacterium tuberculosis induces protective immune responses to a modified live porcine reproductive and respiratory syndrome virus vaccine in pigs
    • V. Dwivedi, C. Manickam, R. Patterson, K. Dodson, M. Weeman, and G. J. Renukaradhya, Intranasal delivery of whole cell lysate of Mycobacterium tuberculosis induces protective immune responses to a modified live porcine reproductive and respiratory syndrome virus vaccine in pigs. Vaccine. 29, 4067 (2011).
    • (2011) Vaccine , vol.29 , pp. 4067
    • Dwivedi, V.1    Manickam, C.2    Patterson, R.3    Dodson, K.4    Weeman, M.5    Renukaradhya, G.J.6
  • 94
  • 95
    • 84875945751 scopus 로고    scopus 로고
    • Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice
    • X. Qian, J. M. Song, T. Melkamu, P. Upadhyaya, and F. Kassie, Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice. Carcinogenesis. 34, 841 (2013).
    • (2013) Carcinogenesis , vol.34 , pp. 841
    • Qian, X.1    Song, J.M.2    Melkamu, T.3    Upadhyaya, P.4    Kassie, F.5
  • 97
    • 79958245618 scopus 로고    scopus 로고
    • Intranasal immunization with poly(gamma-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity
    • K. Matsuo, H. Koizumi, M. Akashi, S. Nakagawa, T. Fujita, A. Yamamoto, and N. Okada, Intranasal immunization with poly(gamma-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity. J. Control Release 152, 310 (2011).
    • (2011) J. Control Release , vol.152 , pp. 310
    • Matsuo, K.1    Koizumi, H.2    Akashi, M.3    Nakagawa, S.4    Fujita, T.5    Yamamoto, A.6    Okada, N.7
  • 98
    • 79957991667 scopus 로고    scopus 로고
    • Effect of wheat germ agglutinin density on cellular uptake and toxicity of wheat germ agglutinin conjugated PEG-PLA nanoparticles in Calu-3 cells
    • Y. Shen, J. Chen, Q. Liu, C. Feng, X. Gao, L. Wang, Q. Zhang, and X. Jiang, Effect of wheat germ agglutinin density on cellular uptake and toxicity of wheat germ agglutinin conjugated PEG-PLA nanoparticles in Calu-3 cells. Int. J. Pharm. 413, 184 (2011).
    • (2011) Int. J. Pharm. , vol.413 , pp. 184
    • Shen, Y.1    Chen, J.2    Liu, Q.3    Feng, C.4    Gao, X.5    Wang, L.6    Zhang, Q.7    Jiang, X.8
  • 99
    • 77954120438 scopus 로고    scopus 로고
    • Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA
    • B. Ghosn, A. Singh, M. Li, A. V. Vlassov, C. Burnett, N. Puri, and K. Roy, Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA. Oligonucleotides 20, 163 (2010).
    • (2010) Oligonucleotides , vol.20 , pp. 163
    • Ghosn, B.1    Singh, A.2    Li, M.3    Vlassov, A.V.4    Burnett, C.5    Puri, N.6    Roy, K.7
  • 100
    • 72049111258 scopus 로고    scopus 로고
    • Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice
    • S. Zhou, S. Kawakami, F. Yamashita, and M. Hashida, Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Cancer Lett. 287, 75 (2010).
    • (2010) Cancer Lett. , vol.287 , pp. 75
    • Zhou, S.1    Kawakami, S.2    Yamashita, F.3    Hashida, M.4
  • 102
    • 67549093924 scopus 로고    scopus 로고
    • Liposomal encapsulation of deguelin: Evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis
    • J. K. Woo, D. S. Choi, H. T. Tran, B. E. Gilbert, W. K. Hong, and H. Y. Lee, Liposomal encapsulation of deguelin: Evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis. Cancer Prev. Res. 2, 361 (2009).
    • (2009) Cancer Prev. Res. , vol.2 , pp. 361
    • Woo, J.K.1    Choi, D.S.2    Tran, H.T.3    Gilbert, B.E.4    Hong, W.K.5    Lee, H.Y.6
  • 104
    • 84878559366 scopus 로고    scopus 로고
    • Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes
    • G. Shim, H. W. Choi, S. Lee, J. Choi, Y. H. Yu, D. E. Park, Y. Choi, C. W. Kim, and Y. K. Oh, Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes. Mol. Ther. 21, 816 (2013).
    • (2013) Mol. Ther. , vol.21 , pp. 816
    • Shim, G.1    Choi, H.W.2    Lee, S.3    Choi, J.4    Yu, Y.H.5    Park, D.E.6    Choi, Y.7    Kim, C.W.8    Oh, Y.K.9
  • 105
    • 84860163790 scopus 로고    scopus 로고
    • Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth
    • A. Kawabata, A. Baoum, N. Ohta, S. Jacquez, G. M. Seo, C. Berkland, and M. Tamura, Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth. Cancer Res. 72, 2057 (2012).
    • (2012) Cancer Res. , vol.72 , pp. 2057
    • Kawabata, A.1    Baoum, A.2    Ohta, N.3    Jacquez, S.4    Seo, G.M.5    Berkland, C.6    Tamura, M.7
  • 106
    • 84861692245 scopus 로고    scopus 로고
    • A new liposome-based gene delivery system targeting lung epithelial cells using endothelin antagonist
    • N. Allon, A. Saxena, C. Chambers, and B. P. Doctor, A new liposome-based gene delivery system targeting lung epithelial cells using endothelin antagonist. J. Control Release 160, 217 (2012).
    • (2012) J. Control Release , vol.160 , pp. 217
    • Allon, N.1    Saxena, A.2    Chambers, C.3    Doctor, B.P.4
  • 107
    • 79955468361 scopus 로고    scopus 로고
    • Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice
    • A. Beyerle, A. Braun, O. Merkel, F. Koch, T. Kissel, and T. Stoeger, Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice. J. Control Release 151, 51 (2011).
    • (2011) J. Control Release , vol.151 , pp. 51
    • Beyerle, A.1    Braun, A.2    Merkel, O.3    Koch, F.4    Kissel, T.5    Stoeger, T.6
  • 110
    • 0034107229 scopus 로고    scopus 로고
    • Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: Uses and limitations
    • K. E. Driscoll, D. L. Costa, G. Hatch, R. Henderson, G. Oberdorster, H. Salem, and R. B. Schlesinger, Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: Uses and limitations. Toxicol. Sci. 55, 24 (2000).
    • (2000) Toxicol. Sci. , vol.55 , pp. 24
    • Driscoll, K.E.1    Costa, D.L.2    Hatch, G.3    Henderson, R.4    Oberdorster, G.5    Salem, H.6    Schlesinger, R.B.7
  • 113
    • 84877929703 scopus 로고    scopus 로고
    • Continuous production of drug nanoparticle suspensions via wet stirred media milling: A fresh look at the Rehbinder effect
    • A. Monteiro, A. Afolabi, and E. Bilgili, Continuous production of drug nanoparticle suspensions via wet stirred media milling: A fresh look at the Rehbinder effect. Drug Dev. Ind. Pharm. 39, 266 (2013).
    • (2013) Drug Dev. Ind. Pharm. , vol.39 , pp. 266
    • Monteiro, A.1    Afolabi, A.2    Bilgili, E.3
  • 115
    • 33745904988 scopus 로고    scopus 로고
    • Formulation, and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles
    • S. Azarmi, X. Tao, H. Chen, Z. Wang, W. H. Finlay, R. Lobenberg, and W. H. Roa, Formulation, and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles. Int J Pharm. 319, 155 (2006).
    • (2006) Int J Pharm. , vol.319 , pp. 155
    • Azarmi, S.1    Tao, X.2    Chen, H.3    Wang, Z.4    Finlay, W.H.5    Lobenberg, R.6    Roa, W.H.7
  • 116
    • 77955874390 scopus 로고    scopus 로고
    • Preparation and characterization of solid lipid nanoparticles loaded with epirubicin for pulmonary delivery
    • L. Hu, Y. Jia, and WenDing, Preparation and characterization of solid lipid nanoparticles loaded with epirubicin for pulmonary delivery. Die. Pharmazie. 65, 585 (2010).
    • (2010) Die. Pharmazie. , vol.65 , pp. 585
    • Hu, L.1    Jia, Y.2    Ding, W.3
  • 118
    • 57349181474 scopus 로고    scopus 로고
    • Airborne particulate matter and human health: Toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms
    • A. Valavanidis, K. Fiotakis, and T. Vlachogianni, Airborne particulate matter and human health: Toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms. J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. 26, 339 (2008).
    • (2008) J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. , vol.26 , pp. 339
    • Valavanidis, A.1    Fiotakis, K.2    Vlachogianni, T.3
  • 119
    • 79956337963 scopus 로고    scopus 로고
    • Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials
    • F. Zhao, Y. Zhao, Y. Liu, X. Chang, C. Chen, and Y. Zhao, Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small 7, 1322 (2011).
    • (2011) Small , vol.7 , pp. 1322
    • Zhao, F.1    Zhao, Y.2    Liu, Y.3    Chang, X.4    Chen, C.5    Zhao, Y.6
  • 121
    • 84884173898 scopus 로고    scopus 로고
    • Effect of end group modification of DNA-functionalized gold nanoparticles on cellular uptake in HepG2 cells
    • S. Hong, S. Park, J. Park, and J. Yi, Effect of end group modification of DNA-functionalized gold nanoparticles on cellular uptake in HepG2 cells. Colloids Surf B Biointerfaces 112, 415 (2013).
    • (2013) Colloids Surf B Biointerfaces , vol.112 , pp. 415
    • Hong, S.1    Park, S.2    Park, J.3    Yi, J.4
  • 124
    • 84876705813 scopus 로고    scopus 로고
    • Gold nanoparticles induce transcriptional activity of NF-kappaB in a B-lymphocyte cell line
    • M. Sharma, R. L. Salisbury, E. I. Maurer, S. M. Hussain, and C. E. Sulentic, Gold nanoparticles induce transcriptional activity of NF-kappaB in a B-lymphocyte cell line. Nanoscale 5, 3747 (2013).
    • (2013) Nanoscale , vol.5 , pp. 3747
    • Sharma, M.1    Salisbury, R.L.2    Maurer, E.I.3    Hussain, S.M.4    Sulentic, C.E.5
  • 125
    • 84866676318 scopus 로고    scopus 로고
    • Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA
    • R. Huschka, A. Barhoumi, Q. Liu, J. A. Roth, L. Ji, and N. J. Halas, Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA. ACS nano. 6, 7681 (2012).
    • (2012) ACS Nano. , vol.6 , pp. 7681
    • Huschka, R.1    Barhoumi, A.2    Liu, Q.3    Roth, J.A.4    Ji, L.5    Halas, N.J.6
  • 128
    • 84877576274 scopus 로고    scopus 로고
    • Evaluation of EGFR-targeted radioimmuno-gold-nanoparticles as a theranostic agent in a tumor animal model
    • H. W. Kao, Y. Y. Lin, C. C. Chen, K. H. Chi, D. C. Tien, C. C. Hsia, M. H. Lin, and H. E. Wang, Evaluation of EGFR-targeted radioimmuno-gold- nanoparticles as a theranostic agent in a tumor animal model. Bioorg. Med. Chem. Lett. 23, 3180 (2013).
    • (2013) Bioorg. Med. Chem. Lett. , vol.23 , pp. 3180
    • Kao, H.W.1    Lin, Y.Y.2    Chen, C.C.3    Chi, K.H.4    Tien, D.C.5    Hsia, C.C.6    Lin, M.H.7    Wang, H.E.8
  • 129
    • 34547587931 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticle based controlled release, drug delivery, and biosensor systems
    • B. G. Trewyn, S. Giri, Slowing, II, and V. S. Lin, Mesoporous silica nanoparticle based controlled release, drug delivery, and biosensor systems. Chem. Commun. (Camb.) 31, 3236 (2007).
    • (2007) Chem. Commun. (Camb.) , vol.31 , pp. 3236
    • Trewyn, B.G.1    Giri, S.2    Slowing, I.I.3    Lin, V.S.4
  • 131
    • 77956945642 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles for Intracellular Controlled Drug Delivery
    • J. L. Vivero-Escoto, I. I. Slowing, B. G. Trewyn, and V. S. Y. Lin, Mesoporous Silica Nanoparticles for Intracellular Controlled Drug Delivery. Small 6, 1952 (2010).
    • (2010) Small , vol.6 , pp. 1952
    • Vivero-Escoto, J.L.1    Slowing, I.I.2    Trewyn, B.G.3    Lin, V.S.Y.4
  • 133
    • 84887023392 scopus 로고    scopus 로고
    • The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy
    • J. Shen, G. Song, M. An, X. Li, N. Wu, K. Ruan, J. Hu, and R. Hu, The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy. Biomaterials. 35, 316 (2014).
    • (2014) Biomaterials , vol.35 , pp. 316
    • Shen, J.1    Song, G.2    An, M.3    Li, X.4    Wu, N.5    Ruan, K.6    Hu, J.7    Hu, R.8
  • 134
    • 84872360422 scopus 로고    scopus 로고
    • Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells
    • M. Ahamed, Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells. Hum. Exp. Toxicol. 32, 186 (2013).
    • (2013) Hum. Exp. Toxicol. , vol.32 , pp. 186
    • Ahamed, M.1
  • 135
    • 33845218637 scopus 로고    scopus 로고
    • In vitro toxicity of silica nanoparticles in human lung cancer cells
    • W. Lin, Y. W. Huang, X. D. Zhou, and Y. Ma, In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol. Appl. Pharmacol. 217, 252 (2006).
    • (2006) Toxicol. Appl. Pharmacol. , vol.217 , pp. 252
    • Lin, W.1    Huang, Y.W.2    Zhou, X.D.3    Ma, Y.4
  • 136
    • 46249115401 scopus 로고    scopus 로고
    • Endocytosis of a single mesoporous silica nanoparticle into a human lung cancer cell observed by differential interference contrast microscopy
    • W. Sun, N. Fang, B. G. Trewyn, M. Tsunoda, Slowing, II, V. S. Lin and E. S. Yeung, Endocytosis of a single mesoporous silica nanoparticle into a human lung cancer cell observed by differential interference contrast microscopy. Anal. Bioanal. Chem. 391, 2119 (2008).
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 2119
    • Sun, W.1    Fang, N.2    Trewyn, B.G.3    Tsunoda, M.4    Slowing, I.I.5    Lin, V.S.6    Yeung, E.S.7
  • 137
    • 84885178933 scopus 로고    scopus 로고
    • Synthesis and characterization of PEG-iron oxide core-shell composite nanoparticles for thermal therapy
    • R. J. Wydra, A. M. Kruse, Y. Bae, K. W. Anderson, and J. Z. Hilt, Synthesis and characterization of PEG-iron oxide core-shell composite nanoparticles for thermal therapy. Mater. Sci. Eng. C Mater. Biol. Appl. 33, 4660 (2013).
    • (2013) Mater. Sci. Eng. C Mater. Biol. Appl. , vol.33 , pp. 4660
    • Wydra, R.J.1    Kruse, A.M.2    Bae, Y.3    Anderson, K.W.4    Hilt, J.Z.5
  • 140
    • 84877043472 scopus 로고    scopus 로고
    • Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy
    • T. Sadhukha, T. S. Wiedmann, and J. Panyam, Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy. Biomaterials 34, 5163 (2013).
    • (2013) Biomaterials , vol.34 , pp. 5163
    • Sadhukha, T.1    Wiedmann, T.S.2    Panyam, J.3
  • 141
    • 84867880074 scopus 로고    scopus 로고
    • Magnetic liposome mediated shRNA specifically suppresses the growth of non-small cell lung cancer in vitro and in vivo
    • C. M. Wang, M. J. Kong, and A. Q. Dong, [Magnetic liposome mediated shRNA specifically suppresses the growth of non-small cell lung cancer in vitro and in vivo]. Zhonghua yi xue za zhi. 92, 341 (2012).
    • (2012) Zhonghua Yi Xue Za Zhi , vol.92 , pp. 341
    • Wang, C.M.1    Kong, M.J.2    Dong, A.Q.3
  • 143
    • 84870423036 scopus 로고    scopus 로고
    • Role of surface charge in cytotoxicity of charged manganese ferrite nanoparticles towards macrophages
    • S. H. Yang, D. Heo, J. Park, S. Na, J. S. Suh, S. Haam, S. W. Park, Y. M. Huh, and J. Yang, Role of surface charge in cytotoxicity of charged manganese ferrite nanoparticles towards macrophages. Nanotechnology 23, 505702 (2012).
    • (2012) Nanotechnology , vol.23 , pp. 505702
    • Yang, S.H.1    Heo, D.2    Park, J.3    Na, S.4    Suh, J.S.5    Haam, S.6    Park, S.W.7    Huh, Y.M.8    Yang, J.9
  • 144
    • 84882800683 scopus 로고    scopus 로고
    • Surface charge-switchable polymeric magnetic nanoparticles for the controlled release of anticancer drug
    • J. M. Shen, T. Yin, X. Z. Tian, F. Y. Gao, and S. Xu, Surface charge-switchable polymeric magnetic nanoparticles for the controlled release of anticancer drug. ACS Appl. Mater. Interfaces. 5, 7014 (2013).
    • (2013) ACS Appl. Mater. Interfaces. , vol.5 , pp. 7014
    • Shen, J.M.1    Yin, T.2    Tian, X.Z.3    Gao, F.Y.4    Xu, S.5
  • 145
    • 84896732597 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticles (SPIONs)-loaded Trojan microparticles for targeted aerosol delivery to the lung
    • F. Tewes, C. Ehrhardt, and A. M. Healy, Superparamagnetic iron oxide nanoparticles (SPIONs)-loaded Trojan microparticles for targeted aerosol delivery to the lung. Eur. J. Pharm. Biopharm. 86, 98 (2013).
    • (2013) Eur. J. Pharm. Biopharm. , vol.86 , pp. 98
    • Tewes, F.1    Ehrhardt, C.2    Healy, A.M.3
  • 147
    • 84888378566 scopus 로고    scopus 로고
    • Preparation and characterization of novel magnetic nano-in-microparticles for site-specific pulmonary drug delivery
    • A. A. McBride, D. N. Price, L. R. Lamoureux, A. A. Elmaoued, J. M. Vargas, N. L. Adolphi, and P. Muttil, Preparation and characterization of novel magnetic nano-in-microparticles for site-specific pulmonary drug delivery. Mol. Pharm. 10, 3574 (2013).
    • (2013) Mol. Pharm. , vol.10 , pp. 3574
    • McBride, A.A.1    Price, D.N.2    Lamoureux, L.R.3    Elmaoued, A.A.4    Vargas, J.M.5    Adolphi, N.L.6    Muttil, P.7
  • 148
    • 83355166280 scopus 로고    scopus 로고
    • Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles
    • M. I. Khan, A. Mohammad, G. Patil, S. A. Naqvi, L. K. Chauhan, and I. Ahmad, Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles. Biomaterials. 33, 1477 (2012).
    • (2012) Biomaterials , vol.33 , pp. 1477
    • Khan, M.I.1    Mohammad, A.2    Patil, G.3    Naqvi, S.A.4    Chauhan, L.K.5    Ahmad, I.6
  • 150
    • 63449105617 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of silver nanoparticles in human cells
    • P. V. AshaRani, G. Low Kah Mun, M. P. Hande, and S. Valiyaveettil, Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS nano. 3, 279 (2009).
    • (2009) ACS Nano. , vol.3 , pp. 279
    • AshaRani, P.V.1    Low Kah Mun, G.2    Hande, M.P.3    Valiyaveettil, S.4
  • 151
    • 84865423058 scopus 로고    scopus 로고
    • The influence of the surface chemistry of silver nanoparticles on cell death
    • I. Sur, M. Altunbek, M. Kahraman, and M. Culha, The influence of the surface chemistry of silver nanoparticles on cell death. Nanotechnology 23, 375102 (2012).
    • (2012) Nanotechnology , vol.23 , pp. 375102
    • Sur, I.1    Altunbek, M.2    Kahraman, M.3    Culha, M.4
  • 152
    • 80053560228 scopus 로고    scopus 로고
    • Oxidative stress induced apoptosis of human lung carcinoma (A549) cells by a novel copper nanorod formulation
    • M. C. Thounaojam, R. N. Jadeja, M. Valodkar, P. S. Nagar, R. V. Devkar, and S. Thakore, Oxidative stress induced apoptosis of human lung carcinoma (A549) cells by a novel copper nanorod formulation. Food Chem. Toxicol. 49, 2990 (2011).
    • (2011) Food Chem. Toxicol. , vol.49 , pp. 2990
    • Thounaojam, M.C.1    Jadeja, R.N.2    Valodkar, M.3    Nagar, P.S.4    Devkar, R.V.5    Thakore, S.6
  • 153
  • 154
    • 84862330295 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species
    • M. J. Akhtar, M. Ahamed, S. Kumar, M. M. Khan, J. Ahmad, and S. A. Alrokayan, Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species. Int. J. Nanomedicine. 7, 845 (2012).
    • (2012) Int. J. Nanomedicine. , vol.7 , pp. 845
    • Akhtar, M.J.1    Ahamed, M.2    Kumar, S.3    Khan, M.M.4    Ahmad, J.5    Alrokayan, S.A.6
  • 155
    • 82255186406 scopus 로고    scopus 로고
    • ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: Role of oxidative stress
    • M. Ahamed, M. J. Akhtar, M. Raja, I. Ahmad, M. K. Siddiqui, M. S. AlSalhi, and S. A. Alrokayan, ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: Role of oxidative stress. Nanomedicine. 7, 904 (2011).
    • (2011) Nanomedicine , vol.7 , pp. 904
    • Ahamed, M.1    Akhtar, M.J.2    Raja, M.3    Ahmad, I.4    Siddiqui, M.K.5    AlSalhi, M.S.6    Alrokayan, S.A.7
  • 157
    • 84885650384 scopus 로고    scopus 로고
    • Single-walled carbon nanotubes mediated targeted tamoxifen delivery system using aspargine-glycine-arginine peptide
    • C. Chen, L. Hou, H. Zhang, L. Zhu, H. Zhang, C. Zhang, J. Shi, L. Wang, X. Jia, and Z. Zhang, Single-walled carbon nanotubes mediated targeted tamoxifen delivery system using aspargine-glycine-arginine peptide. J. Drug Target. 21, 809 (2013).
    • (2013) J. Drug Target. , vol.21 , pp. 809
    • Chen, C.1    Hou, L.2    Zhang, H.3    Zhu, L.4    Zhang, H.5    Zhang, C.6    Shi, J.7    Wang, L.8    Jia, X.9    Zhang, Z.10
  • 158
    • 84875316354 scopus 로고    scopus 로고
    • Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers
    • V. Castranova, P. A. Schulte, and R. D. Zumwalde, Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers. Acc. Chem. Res. 46, 642 (2013).
    • (2013) Acc. Chem. Res. , vol.46 , pp. 642
    • Castranova, V.1    Schulte, P.A.2    Zumwalde, R.D.3
  • 159
    • 75249100931 scopus 로고    scopus 로고
    • Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: Toxic effects are determined by density of agglomerate structures, not fibrillar structures
    • J. Pauluhn, Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: Toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol. Sci. 113, 226 (2010).
    • (2010) Toxicol. Sci. , vol.113 , pp. 226
    • Pauluhn, J.1
  • 160
    • 70449674076 scopus 로고    scopus 로고
    • Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes) relative to alpha-quartz following a single 6h inhalation exposure of rats and a 3 months post-exposure period
    • H. Ellinger-Ziegelbauer and J. Pauluhn, Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes) relative to alpha-quartz following a single 6h inhalation exposure of rats and a 3 months post-exposure period. Toxicology 266, 16 (2009).
    • (2009) Toxicology , vol.266 , pp. 16
    • Ellinger-Ziegelbauer, H.1    Pauluhn, J.2
  • 161
    • 67649890883 scopus 로고    scopus 로고
    • Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model
    • J. E. Podesta, K. T. Al-Jamal, M. A. Herrero, B. Tian, H. Ali-Boucetta, V. Hegde, A. Bianco, M. Prato, and K. Kostarelos, Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model. Small 5, 1176 (2009).
    • (2009) Small , vol.5 , pp. 1176
    • Podesta, J.E.1    Al-Jamal, K.T.2    Herrero, M.A.3    Tian, B.4    Ali-Boucetta, H.5    Hegde, V.6    Bianco, A.7    Prato, M.8    Kostarelos, K.9
  • 163
    • 56549127420 scopus 로고    scopus 로고
    • Water-dispersed single-wall carbon nanohorns as drug carriers for local cancer chemotherapy
    • T. Murakami, H. Sawada, G. Tamura, M. Yudasaka, S. Iijima, and K. Tsuchida, Water-dispersed single-wall carbon nanohorns as drug carriers for local cancer chemotherapy. Nanomedicine (Lon) 3, 453 (2008).
    • (2008) Nanomedicine (Lon) , vol.3 , pp. 453
    • Murakami, T.1    Sawada, H.2    Tamura, G.3    Yudasaka, M.4    Iijima, S.5    Tsuchida, K.6
  • 164
    • 56849132060 scopus 로고    scopus 로고
    • Enhancement of in vivo anticancer effects of cisplatin by incorporation inside single-wall carbon nanohorns
    • K. Ajima, T. Murakami, Y. Mizoguchi, K. Tsuchida, T. Ichihashi, S. Iijima, and M. Yudasaka, Enhancement of in vivo anticancer effects of cisplatin by incorporation inside single-wall carbon nanohorns. ACS nano. 2, 2057 (2008).
    • (2008) ACS Nano. , vol.2 , pp. 2057
    • Ajima, K.1    Murakami, T.2    Mizoguchi, Y.3    Tsuchida, K.4    Ichihashi, T.5    Iijima, S.6    Yudasaka, M.7
  • 165
    • 84891691816 scopus 로고    scopus 로고
    • Improvement of the antiproliferative effect of Rapamycin on tumor cell lines by poly (monomethylitaconate)-based pH-sensitive, plasma stable liposomes
    • S. Ghanbarzadeh, S. Arami, Z. Pourmoazzen, and A. Khorrami, Improvement of the antiproliferative effect of Rapamycin on tumor cell lines by poly (monomethylitaconate)-based pH-sensitive, plasma stable liposomes. Colloids Surf. B Biointerfaces 115C, 323 (2013).
    • (2013) Colloids Surf. B Biointerfaces , vol.115 C , pp. 323
    • Ghanbarzadeh, S.1    Arami, S.2    Pourmoazzen, Z.3    Khorrami, A.4
  • 166
    • 84890245521 scopus 로고    scopus 로고
    • Simultaneous delivery of doxorubicin and curcumin encapsulated in liposomes of pegylated RGDK-lipopeptide to tumor vasculature
    • S. Barui, S. Saha, G. Mondal, S. Haseena, and A. Chaudhuri, Simultaneous delivery of doxorubicin and curcumin encapsulated in liposomes of pegylated RGDK-lipopeptide to tumor vasculature. Biomaterials 35, 1643 (2014).
    • (2014) Biomaterials , vol.35 , pp. 1643
    • Barui, S.1    Saha, S.2    Mondal, G.3    Haseena, S.4    Chaudhuri, A.5
  • 167
    • 84863479128 scopus 로고    scopus 로고
    • Therapeutic liposomal dry powder inhalation aerosols for targeted lung delivery
    • L. Willis, D. Hayes, Jr., and H. M. Mansour, Therapeutic liposomal dry powder inhalation aerosols for targeted lung delivery. Lung 190, 251 (2012).
    • (2012) Lung , vol.190 , pp. 251
    • Willis, L.1    Hayes Jr., D.2    Mansour, H.M.3
  • 168
    • 84884553984 scopus 로고    scopus 로고
    • Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery
    • J. Duan, F. G. Vogt, X. Li, D. Hayes, Jr., and H. M. Mansour, Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery. Int. J Nanomedicine. 8, 3489 (2013).
    • (2013) Int. J Nanomedicine , vol.8 , pp. 3489
    • Duan, J.1    Vogt, F.G.2    Li, X.3    Hayes Jr., D.4    Mansour, H.M.5
  • 169
    • 44749085853 scopus 로고    scopus 로고
    • Molecular interactions of cord factor with dipalmitoylphosphatidylcholine monolayers: Implications for lung surfactant dysfunction in pulmonary tuberculosis
    • G. Chimote and R. Banerjee, Molecular interactions of cord factor with dipalmitoylphosphatidylcholine monolayers: Implications for lung surfactant dysfunction in pulmonary tuberculosis. Colloids Surf. B Biointerfaces 65, 120 (2008).
    • (2008) Colloids Surf. B Biointerfaces , vol.65 , pp. 120
    • Chimote, G.1    Banerjee, R.2
  • 171
    • 0036203989 scopus 로고    scopus 로고
    • Growth inhibition of established B16-F10 lung metastases by sequential aerosol delivery of p53 gene and 9-nitrocamptothecin
    • A. Gautam, J. C. Waldrep, C. L. Densmore, N. Koshkina, S. Melton, L. Roberts, B. Gilbert, and V. Knight, Growth inhibition of established B16-F10 lung metastases by sequential aerosol delivery of p53 gene and 9-nitrocamptothecin. Gene Therapy 9, 353 (2002).
    • (2002) Gene Therapy , vol.9 , pp. 353
    • Gautam, A.1    Waldrep, J.C.2    Densmore, C.L.3    Koshkina, N.4    Melton, S.5    Roberts, L.6    Gilbert, B.7    Knight, V.8
  • 172
    • 0037442041 scopus 로고    scopus 로고
    • Potent inhibition of angiogenesis and liver tumor growth by administration of an aerosol containing a transferrin-liposome-endostatin complex
    • X. Li, G. F. Fu, Y. R. Fan, C. F. Shi, X. J. Liu, G. X. Xu, and J. J. Wang, Potent inhibition of angiogenesis and liver tumor growth by administration of an aerosol containing a transferrin-liposome-endostatin complex. World J. Gastroenterol. 9, 262 (2003).
    • (2003) World J. Gastroenterol. , vol.9 , pp. 262
    • Li, X.1    Fu, G.F.2    Fan, Y.R.3    Shi, C.F.4    Liu, X.J.5    Xu, G.X.6    Wang, J.J.7
  • 173
    • 84875236608 scopus 로고    scopus 로고
    • The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer
    • J. Zhou, W. Y. Zhao, X. Ma, R. J. Ju, X. Y. Li, N. Li, M. G. Sun, J. F. Shi, C. X. Zhang, and W. L. Lu, The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. Biomaterials 34, 3626 (2013).
    • (2013) Biomaterials , vol.34 , pp. 3626
    • Zhou, J.1    Zhao, W.Y.2    Ma, X.3    Ju, R.J.4    Li, X.Y.5    Li, N.6    Sun, M.G.7    Shi, J.F.8    Zhang, C.X.9    Lu, W.L.10
  • 174
    • 70349679107 scopus 로고    scopus 로고
    • Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases
    • P. Latimer, M. Menchaca, R. M. Snyder, W. Yu, B. E. Gilbert, B. G. Sanders, and K. Kline, Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases. Exp. Biol. Med. (Maywood, N.J.) 234, 1244 (2009).
    • (2009) Exp. Biol. Med. (Maywood, N.J.) , vol.234 , pp. 1244
    • Latimer, P.1    Menchaca, M.2    Snyder, R.M.3    Yu, W.4    Gilbert, B.E.5    Sanders, B.G.6    Kline, K.7
  • 176
    • 1842479077 scopus 로고    scopus 로고
    • Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies
    • C. F. Verschraegen, B. E. Gilbert, E. Loyer, A. Huaringa, G. Walsh, R. A. Newman, and V. Knight, Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies. Clin. Cancer Res. 10, 2319 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2319
    • Verschraegen, C.F.1    Gilbert, B.E.2    Loyer, E.3    Huaringa, A.4    Walsh, G.5    Newman, R.A.6    Knight, V.7
  • 177
    • 84872120013 scopus 로고    scopus 로고
    • Efficient down-regulation of PKC-alpha gene expression in A549 lung cancer cells mediated by antisense oligodeoxynucleotides in dendrosomes
    • S. Movassaghian, H. R. Moghimi, F. H. Shirazi, A. Koshkaryev, M. S. Trivedi, and V. P. Torchilin, Efficient down-regulation of PKC-alpha gene expression in A549 lung cancer cells mediated by antisense oligodeoxynucleotides in dendrosomes. Int. J. Pharm. 441, 82 (2013).
    • (2013) Int. J. Pharm. , vol.441 , pp. 82
    • Movassaghian, S.1    Moghimi, H.R.2    Shirazi, F.H.3    Koshkaryev, A.4    Trivedi, M.S.5    Torchilin, V.P.6
  • 178
    • 35548968849 scopus 로고    scopus 로고
    • Lipoplex morphologies and their influences on transfection efficiency in gene delivery
    • B. Ma, S. Zhang, H. Jiang, B. Zhao, and H. Lv, Lipoplex morphologies and their influences on transfection efficiency in gene delivery. J. Control Release 123, 184 (2007).
    • (2007) J. Control Release , vol.123 , pp. 184
    • Ma, B.1    Zhang, S.2    Jiang, H.3    Zhao, B.4    Lv, H.5
  • 180
    • 84855826986 scopus 로고    scopus 로고
    • Liposomal formulations of Etoposide and Docetaxel for p53 mediated enhanced cytotoxicity in lung cancer cell lines
    • K. A. Jinturkar, C. Anish, M. K. Kumar, T. Bagchi, A. K. Panda and A. R. Misra, Liposomal formulations of Etoposide and Docetaxel for p53 mediated enhanced cytotoxicity in lung cancer cell lines. Biomaterials 33, 2492 (2012).
    • (2012) Biomaterials , vol.33 , pp. 2492
    • Jinturkar, K.A.1    Anish, C.2    Kumar, M.K.3    Bagchi, T.4    Panda, A.K.5    Misra, A.R.6
  • 181
    • 84878107502 scopus 로고    scopus 로고
    • Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances complement-dependent anti-tumor activity of trastuzumab and pertuzumab
    • S. Mamidi, M. Cinci, M. Hasmann, V. Fehring, and M. Kirschfink, Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances complement-dependent anti-tumor activity of trastuzumab and pertuzumab. Mol. Oncol. 7, 580 (2013).
    • (2013) Mol. Oncol. , vol.7 , pp. 580
    • Mamidi, S.1    Cinci, M.2    Hasmann, M.3    Fehring, V.4    Kirschfink, M.5
  • 182
    • 79960054148 scopus 로고    scopus 로고
    • Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo
    • C. Wang, C. Ding, M. Kong, A. Dong, J. Qian, D. Jiang, and Z. Shen, Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo. Biochem. Biophys. Res. Commun. 410, 537 (2011).
    • (2011) Biochem. Biophys. Res. Commun. , vol.410 , pp. 537
    • Wang, C.1    Ding, C.2    Kong, M.3    Dong, A.4    Qian, J.5    Jiang, D.6    Shen, Z.7
  • 184
    • 84874256639 scopus 로고    scopus 로고
    • Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy
    • Y. Zhang, W. Y. Kim, and L. Huang, Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy. Biomaterials 34, 3447 (2013).
    • (2013) Biomaterials , vol.34 , pp. 3447
    • Zhang, Y.1    Kim, W.Y.2    Huang, L.3
  • 185
    • 84857795022 scopus 로고    scopus 로고
    • Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis
    • Y. Yang, J. Li, F. Liu, and L. Huang, Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis. Mol. Ther. 20, 609 (2012).
    • (2012) Mol. Ther. , vol.20 , pp. 609
    • Yang, Y.1    Li, J.2    Liu, F.3    Huang, L.4
  • 186
    • 84884278759 scopus 로고    scopus 로고
    • Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis
    • Z. Xu, S. Ramishetti, Y. C. Tseng, S. Guo, Y. Wang, and L. Huang, Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis. J. Control Release 172, 259 (2013).
    • (2013) J. Control Release , vol.172 , pp. 259
    • Xu, Z.1    Ramishetti, S.2    Tseng, Y.C.3    Guo, S.4    Wang, Y.5    Huang, L.6
  • 187
    • 84870675676 scopus 로고    scopus 로고
    • New approach to improve encapsulation and antitumor activity of doxorubicin loaded in solid lipid nanoparticles
    • S. V. Mussi, R. C. Silva, M. C. Oliveira, C. M. Lucci, R. B. Azevedo, and L. A. Ferreira, New approach to improve encapsulation and antitumor activity of doxorubicin loaded in solid lipid nanoparticles. Eur. J. Pharm. Sci. 48, 282 (2013).
    • (2013) Eur. J. Pharm. Sci. , vol.48 , pp. 282
    • Mussi, S.V.1    Silva, R.C.2    Oliveira, M.C.3    Lucci, C.M.4    Azevedo, R.B.5    Ferreira, L.A.6
  • 189
    • 47949130908 scopus 로고    scopus 로고
    • PEGylated nanostructured lipid carriers loaded with 10- hydroxycamptothecin: An efficient carrier with enhanced anti-tumour effects against lung cancer
    • X. Zhang, Y. Gan, L. Gan, S. Nie, and W. Pan, PEGylated nanostructured lipid carriers loaded with 10-hydroxycamptothecin: An efficient carrier with enhanced anti-tumour effects against lung cancer. J. Pharm. Pharmacol. 60, 1077 (2008).
    • (2008) J. Pharm. Pharmacol. , vol.60 , pp. 1077
    • Zhang, X.1    Gan, Y.2    Gan, L.3    Nie, S.4    Pan, W.5
  • 190
    • 84876492723 scopus 로고    scopus 로고
    • Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel
    • A. R. Patel, M. B. Chougule, T. I. R. Patlolla, G. Wang, and M. Singh, Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel. Pharm. Res. 30, 1435 (2013).
    • (2013) Pharm. Res. , vol.30 , pp. 1435
    • Patel, A.R.1    Chougule, M.B.2    Patlolla, T.I.R.3    Wang, G.4    Singh, M.5
  • 191
    • 84863777799 scopus 로고    scopus 로고
    • Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung
    • M. Dong, T. E. Murdter, C. Philippi, B. Loretz, U. F. Schaefer, C. M. Lehr, M. Schwab, and S. Ammon-Treiber, Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung. Eur. J. Pharm. Biopharm. 81, 478 (2012).
    • (2012) Eur. J. Pharm. Biopharm. , vol.81 , pp. 478
    • Dong, M.1    Murdter, T.E.2    Philippi, C.3    Loretz, B.4    Schaefer, U.F.5    Lehr, C.M.6    Schwab, M.7    Ammon-Treiber, S.8
  • 193
    • 77955662556 scopus 로고    scopus 로고
    • Secondary cytotoxicity mediated by alveolar macrophages: A contribution to the total efficacy of nanoparticles in lung cancer therapy?
    • K. M. Al-Hallak, S. Azarmi, A. Anwar-Mohamed, W. H. Roa, and R. Lobenberg, Secondary cytotoxicity mediated by alveolar macrophages: A contribution to the total efficacy of nanoparticles in lung cancer therapy? Eur. J. Pharm. Biopharm. 76, 112 (2010).
    • (2010) Eur. J. Pharm. Biopharm. , vol.76 , pp. 112
    • Al-Hallak, K.M.1    Azarmi, S.2    Anwar-Mohamed, A.3    Roa, W.H.4    Lobenberg, R.5
  • 196
    • 84879707211 scopus 로고    scopus 로고
    • Synergistic Interaction of Paclitaxel and Curcumin with Cyclodextrin Polymer Complexation in Human Cancer Cells
    • A. O. Boztas, O. Karakuzu, G. Galante, Z. Ugur, F. Kocabas, C. Z. Altuntas, and A. O. Yazaydin, Synergistic Interaction of Paclitaxel and Curcumin with Cyclodextrin Polymer Complexation in Human Cancer Cells. Mol. Pharm. 10, 2676 (2013).
    • (2013) Mol. Pharm. , vol.10 , pp. 2676
    • Boztas, A.O.1    Karakuzu, O.2    Galante, G.3    Ugur, Z.4    Kocabas, F.5    Altuntas, C.Z.6    Yazaydin, A.O.7
  • 198
    • 84867494034 scopus 로고    scopus 로고
    • Native and beta-cyclodextrin-enclosed curcumin: Entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer
    • S. Rahman, S. Cao, K. J. Steadman, M. Wei, and H. S. Parekh, Native and beta-cyclodextrin-enclosed curcumin: Entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer. Drug Deliv. 19, 346 (2012).
    • (2012) Drug Deliv. , vol.19 , pp. 346
    • Rahman, S.1    Cao, S.2    Steadman, K.J.3    Wei, M.4    Parekh, H.S.5
  • 199
    • 79251549800 scopus 로고    scopus 로고
    • Hydroxypropyl-beta-cyclodextrin copolymers and their nanoparticles as doxorubicin delivery system
    • T. Wang, C. Zhang, X. J. Liang, W. Liang, and Y. Wu, Hydroxypropyl-beta- cyclodextrin copolymers and their nanoparticles as doxorubicin delivery system. J. Pharm. Sci. 100, 1067 (2011).
    • (2011) J. Pharm. Sci. , vol.100 , pp. 1067
    • Wang, T.1    Zhang, C.2    Liang, X.J.3    Liang, W.4    Wu, Y.5
  • 201
    • 84878104912 scopus 로고    scopus 로고
    • Paclitaxel nano-delivery systems: A comprehensive review
    • P. Ma and R. J. Mumper, Paclitaxel nano-delivery systems: A comprehensive review. J. Nanomed. Nanotechnol. 4, 1000164 (2013).
    • (2013) J. Nanomed. Nanotechnol. , vol.4 , pp. 1000164
    • Ma, P.1    Mumper, R.J.2
  • 202
    • 84872289754 scopus 로고    scopus 로고
    • Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: Optimization and in vitro, in vivo evaluation
    • L. Chen, X. Sha, X. Jiang, Y. Chen, Q. Ren, and X. Fang, Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: Optimization and in vitro, in vivo evaluation. Int. J. Nanomedicine 8, 73 (2013).
    • (2013) Int. J. Nanomedicine , vol.8 , pp. 73
    • Chen, L.1    Sha, X.2    Jiang, X.3    Chen, Y.4    Ren, Q.5    Fang, X.6
  • 203
    • 33847769463 scopus 로고    scopus 로고
    • Amphiphilic triblock copolymer poly(p-dioxanone-co-L-lactide)-block- poly(ethylene glycol), enhancement of gene expression and inhibition of lung metastasis by aerosol delivery
    • S. R. Bhattarai, S. Y. Kim, K. Y. Jang, H. K. Yi, Y. H. Lee, N. Bhattarai, S. Y. Nam, D. Y. Lee, H. Y. Kim, and P. H. Hwang, Amphiphilic triblock copolymer poly(p-dioxanone-co-L-lactide)-block-poly(ethylene glycol), enhancement of gene expression and inhibition of lung metastasis by aerosol delivery. Gene Ther. 14, 476 (2007).
    • (2007) Gene Ther. , vol.14 , pp. 476
    • Bhattarai, S.R.1    Kim, S.Y.2    Jang, K.Y.3    Yi, H.K.4    Lee, Y.H.5    Bhattarai, N.6    Nam, S.Y.7    Lee, D.Y.8    Kim, H.Y.9    Hwang, P.H.10
  • 204
    • 84868316414 scopus 로고    scopus 로고
    • Methoxypoly(ethylene glycol)-block-poly(L-glutamic acid)-loaded cisplatin and a combination with iRGD for the treatment of non-small-cell lung cancers
    • W. Song, M. Li, Z. Tang, Q. Li, Y. Yang, H. Liu, T. Duan, H. Hong and X. Chen, Methoxypoly(ethylene glycol)-block-poly(L-glutamic acid)-loaded cisplatin and a combination with iRGD for the treatment of non-small-cell lung cancers. Macromol. Biosci. 12, 1514 (2012).
    • (2012) Macromol. Biosci. , vol.12 , pp. 1514
    • Song, W.1    Li, M.2    Tang, Z.3    Li, Q.4    Yang, Y.5    Liu, H.6    Duan, T.7    Hong, H.8    Chen, X.9
  • 205
    • 84871463627 scopus 로고    scopus 로고
    • Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma
    • C. Gong, Y. Xie, Q. Wu, Y. Wang, S. Deng, D. Xiong, L. Liu, M. Xiang, Z. Qian, and Y. Wei, Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma. Nanoscale 4, 6004 (2012).
    • (2012) Nanoscale , vol.4 , pp. 6004
    • Gong, C.1    Xie, Y.2    Wu, Q.3    Wang, Y.4    Deng, S.5    Xiong, D.6    Liu, L.7    Xiang, M.8    Qian, Z.9    Wei, Y.10
  • 206
    • 84891786517 scopus 로고    scopus 로고
    • Sequential targeted delivery of Paclitaxel and camptothecin using a cross-linked "nanosponge" network for lung cancer chemotherapy
    • G. Hariri, A. D. Edwards, T. B. Merrill, J. M. Greenbaum, A. E. van der Ende, and E. Harth, Sequential targeted delivery of Paclitaxel and camptothecin using a cross-linked "nanosponge" network for lung cancer chemotherapy. Mol. Pharm. 11, 265 (2014).
    • (2014) Mol. Pharm. , vol.11 , pp. 265
    • Hariri, G.1    Edwards, A.D.2    Merrill, T.B.3    Greenbaum, J.M.4    Van Der Ende, A.E.5    Harth, E.6
  • 207
    • 84876512877 scopus 로고    scopus 로고
    • Pegylated dendrimer and its effect in fluorouracil loading and release for enhancing antitumor activity
    • T. U. Ly, N. Q. Tran, T. K. Hoang, K. N. Phan, H. N. Truong, and C. K. Nguyen, Pegylated dendrimer and its effect in fluorouracil loading and release for enhancing antitumor activity. J. Biomed. Nanotechnol. 9, 213 (2013).
    • (2013) J. Biomed. Nanotechnol. , vol.9 , pp. 213
    • Ly, T.U.1    Tran, N.Q.2    Hoang, T.K.3    Phan, K.N.4    Truong, H.N.5    Nguyen, C.K.6
  • 208
    • 80054081012 scopus 로고    scopus 로고
    • Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery
    • J. Hu, Y. Su, H. Zhang, T. Xu, and Y. Cheng, Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery. Biomaterials 32, 9950 (2011).
    • (2011) Biomaterials , vol.32 , pp. 9950
    • Hu, J.1    Su, Y.2    Zhang, H.3    Xu, T.4    Cheng, Y.5
  • 209
    • 84863230506 scopus 로고    scopus 로고
    • Preparation of cystamine core dendrimer and antibody-dendrimer conjugates for MRI angiography
    • K. Nwe, D. E. Milenic, G. L. Ray, Y. S. Kim, and M. W. Brechbiel, Preparation of cystamine core dendrimer and antibody-dendrimer conjugates for MRI angiography. Mol. Pharm. 9, 374 (2012).
    • (2012) Mol. Pharm. , vol.9 , pp. 374
    • Nwe, K.1    Milenic, D.E.2    Ray, G.L.3    Kim, Y.S.4    Brechbiel, M.W.5
  • 210
    • 84874612902 scopus 로고    scopus 로고
    • Facile formation of folic acid-modified dendrimer-stabilized gold-silver alloy nanoparticles for potential cellular computed tomography imaging applications
    • H. Liu, M. Shen, J. Zhao, J. Zhu, T. Xiao, X. Cao, G. Zhang, and X. Shi, Facile formation of folic acid-modified dendrimer-stabilized gold-silver alloy nanoparticles for potential cellular computed tomography imaging applications. Analyst 138, 1979 (2013).
    • (2013) Analyst , vol.138 , pp. 1979
    • Liu, H.1    Shen, M.2    Zhao, J.3    Zhu, J.4    Xiao, T.5    Cao, X.6    Zhang, G.7    Shi, X.8
  • 212
    • 68549130604 scopus 로고    scopus 로고
    • Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro
    • V. K. Yellepeddi, A. Kumar, and S. Palakurthi, Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro. Anticancer Res. 29, 2933 (2009).
    • (2009) Anticancer Res. , vol.29 , pp. 2933
    • Yellepeddi, V.K.1    Kumar, A.2    Palakurthi, S.3
  • 215
    • 77949275122 scopus 로고    scopus 로고
    • Dendrimer-based drug and imaging conjugates: Design considerations for nanomedical applications
    • A. R. Menjoge, R. M. Kannan, and D. A. Tomalia, Dendrimer-based drug and imaging conjugates: Design considerations for nanomedical applications. Drug Discov. Today 15, 171 (2010).
    • (2010) Drug Discov. Today , vol.15 , pp. 171
    • Menjoge, A.R.1    Kannan, R.M.2    Tomalia, D.A.3
  • 219
    • 84868194129 scopus 로고    scopus 로고
    • Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma
    • H. Wang, L. Zheng, C. Peng, M. Shen, X. Shi, and G. Zhang, Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma. Biomaterials 34, 470 (2013).
    • (2013) Biomaterials , vol.34 , pp. 470
    • Wang, H.1    Zheng, L.2    Peng, C.3    Shen, M.4    Shi, X.5    Zhang, G.6
  • 220
  • 221
    • 33846676987 scopus 로고    scopus 로고
    • Chemical genetics: Where genetics and pharmacology meet
    • Z. A. Knight and K. M. Shokat, Chemical genetics: Where genetics and pharmacology meet. Cell 128, 425 (2007).
    • (2007) Cell , vol.128 , pp. 425
    • Knight, Z.A.1    Shokat, K.M.2
  • 223
    • 0038141338 scopus 로고    scopus 로고
    • Fibronectin requirement in branching morphogenesis
    • T. Sakai, M. Larsen, and K. M. Yamada, Fibronectin requirement in branching morphogenesis. Nature 423, 876 (2003).
    • (2003) Nature , vol.423 , pp. 876
    • Sakai, T.1    Larsen, M.2    Yamada, K.M.3
  • 224
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • K. M. Yamada and E. Cukierman, Modeling tissue morphogenesis and cancer in 3D. Cell 130, 601 (2007).
    • (2007) Cell , vol.130 , pp. 601
    • Yamada, K.M.1    Cukierman, E.2
  • 225
    • 0019749891 scopus 로고
    • Preparation and composition of alveolar extracellular matrix and incorporated basement membrane
    • R. Kuttan, R. D. Spall, R. C. Duhamel, I. G. Sipes, E. Meezan, and K. Brendel, Preparation and composition of alveolar extracellular matrix and incorporated basement membrane. Lung 159, 333 (1981).
    • (1981) Lung , vol.159 , pp. 333
    • Kuttan, R.1    Spall, R.D.2    Duhamel, R.C.3    Sipes, I.G.4    Meezan, E.5    Brendel, K.6
  • 227
    • 84858003654 scopus 로고    scopus 로고
    • Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts
    • S. A. Mousa, M. Yalcin, D. J. Bharali, R. Meng, H. Y. Tang, H. Y. Lin, F. B. Davis, and P. J. Davis, Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts. Lung Cancer 76, 39 (2012).
    • (2012) Lung Cancer , vol.76 , pp. 39
    • Mousa, S.A.1    Yalcin, M.2    Bharali, D.J.3    Meng, R.4    Tang, H.Y.5    Lin, H.Y.6    Davis, F.B.7    Davis, P.J.8
  • 228
    • 84872549177 scopus 로고    scopus 로고
    • AlgiMatrix based 3D cell culture system as an in-vitro tumor model for anticancer studies
    • C. Godugu, A. R. Patel, U. Desai, T. Andey, A. Sams, and M. Singh, AlgiMatrix based 3D cell culture system as an in-vitro tumor model for anticancer studies. PLoS One 8, 18 (2013).
    • (2013) PLoS One , vol.8 , pp. 18
    • Godugu, C.1    Patel, A.R.2    Desai, U.3    Andey, T.4    Sams, A.5    Singh, M.6
  • 229
    • 0017873165 scopus 로고
    • Drug absorption from the lung
    • L. S. Schanker, Drug absorption from the lung. Biochem. Pharmacol. 27, 381 (1978).
    • (1978) Biochem. Pharmacol. , vol.27 , pp. 381
    • Schanker, L.S.1
  • 230
    • 0015425028 scopus 로고
    • Absorption of drugs from the rat lung
    • S. J. Enna and L. S. Schanker, Absorption of drugs from the rat lung. Am J Physiol. 223, 1227 (1972).
    • (1972) Am J Physiol. , vol.223 , pp. 1227
    • Enna, S.J.1    Schanker, L.S.2
  • 231
    • 0015713220 scopus 로고
    • Absorption of cardiac glycosides from the rat respiratory tract
    • R. C. Lanman, R. M. Gillilan, and L. S. Schanker, Absorption of cardiac glycosides from the rat respiratory tract. J. Pharmacol. Exp. Ther. 187, 105 (1973).
    • (1973) J. Pharmacol. Exp. Ther. , vol.187 , pp. 105
    • Lanman, R.C.1    Gillilan, R.M.2    Schanker, L.S.3
  • 233
    • 0016169824 scopus 로고
    • Absorption of sulphonamides and antitubercular drugs from the rat lung
    • J. A. Burton and L. S. Schanker, Absorption of sulphonamides and antitubercular drugs from the rat lung. Xenobiotica. 4, 291 (1974).
    • (1974) Xenobiotica. , vol.4 , pp. 291
    • Burton, J.A.1    Schanker, L.S.2
  • 234
    • 0016228157 scopus 로고
    • Absorption of corticosteroids from the rat lung
    • J. A. Burton and L. S. Schanker, Absorption of corticosteroids from the rat lung. Steroids 23, 617 (1974).
    • (1974) Steroids , vol.23 , pp. 617
    • Burton, J.A.1    Schanker, L.S.2
  • 235
    • 0034109921 scopus 로고    scopus 로고
    • Carcinogenesis in mouse and human cells: Parallels and paradoxes
    • A. Balmain and C. C. Harris, Carcinogenesis in mouse and human cells: Parallels and paradoxes. Carcinogenesis 21, 371 (2000).
    • (2000) Carcinogenesis , vol.21 , pp. 371
    • Balmain, A.1    Harris, C.C.2
  • 236
    • 0034997385 scopus 로고    scopus 로고
    • Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung
    • A. M. Malkinson, Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer 32, 265 (2001).
    • (2001) Lung Cancer , vol.32 , pp. 265
    • Malkinson, A.M.1
  • 237
    • 0032789883 scopus 로고    scopus 로고
    • Characterization of a highly metastatic, orthotopic lung cancer model in the nude rat
    • R. B. Howard, J. B. Mullen, M. E. Pagura, and M. R. Johnston, Characterization of a highly metastatic, orthotopic lung cancer model in the nude rat. Clin. Exp. Metastasis 17, 157 (1999).
    • (1999) Clin. Exp. Metastasis , vol.17 , pp. 157
    • Howard, R.B.1    Mullen, J.B.2    Pagura, M.E.3    Johnston, M.R.4
  • 238
    • 0033500248 scopus 로고    scopus 로고
    • Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: A bridge to the clinic
    • R. M. Hoffman, Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: A bridge to the clinic. Invest. New Drugs 17, 343 (1999).
    • (1999) Invest. New Drugs , vol.17 , pp. 343
    • Hoffman, R.M.1
  • 239
    • 0016634319 scopus 로고
    • Lung tumors in mice: Application to carcinogenesis bioassay
    • M. B. Shimkin and G. D. Stoner, Lung tumors in mice: Application to carcinogenesis bioassay. Adv. Cancer Res. 21, 1 (1975).
    • (1975) Adv. Cancer Res. , vol.21 , pp. 1
    • Shimkin, M.B.1    Stoner, G.D.2
  • 240
    • 0029963988 scopus 로고    scopus 로고
    • Induction of benign and malignant pulmonary tumours in mice with benzo(a)pyrene
    • S. H. Kim and C. S. Lee, Induction of benign and malignant pulmonary tumours in mice with benzo(a)pyrene. Anticancer Res. 16, 465 (1996).
    • (1996) Anticancer Res. , vol.16 , pp. 465
    • Kim, S.H.1    Lee, C.S.2
  • 241
    • 0025968509 scopus 로고
    • Lung tumors in strain A mice as a bioassay for carcinogenicity of environmental chemicals
    • G. D. Stoner, Lung tumors in strain A mice as a bioassay for carcinogenicity of environmental chemicals. Exp. Lung Res. 17, 405 (1991).
    • (1991) Exp. Lung Res. , vol.17 , pp. 405
    • Stoner, G.D.1
  • 242
    • 0018903446 scopus 로고
    • Generation of oncogenic mouse type C viruses: In vitro selection of carcinoma-inducing variants
    • U. R. Rapp and G. J. Todaro, Generation of oncogenic mouse type C viruses: In vitro selection of carcinoma-inducing variants. Proc. Natl. Acad. Sci. USA 77, 624 (1980).
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 624
    • Rapp, U.R.1    Todaro, G.J.2
  • 243
    • 0023893457 scopus 로고
    • Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice
    • T. L. McLemore, J. C. Eggleston, R. H. Shoemaker, B. J. Abbott, M. E. Bohlman, M. C. Liu, D. L. Fine, J. G. Mayo, and M. R. Boyd, Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice. Cancer Res. 48, 2880 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 2880
    • McLemore, T.L.1    Eggleston, J.C.2    Shoemaker, R.H.3    Abbott, B.J.4    Bohlman, M.E.5    Liu, M.C.6    Fine, D.L.7    Mayo, J.G.8    Boyd, M.R.9
  • 245
    • 0035883426 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein regulates the growth of orthotopic human lung tumors in athymic mice
    • R. H. Hastings, D. W. Burton, R. A. Quintana, E. Biederman, A. Gujral, and L. J. Deftos, Parathyroid hormone-related protein regulates the growth of orthotopic human lung tumors in athymic mice. Cancer 92, 1402 (2001).
    • (2001) Cancer , vol.92 , pp. 1402
    • Hastings, R.H.1    Burton, D.W.2    Quintana, R.A.3    Biederman, E.4    Gujral, A.5    Deftos, L.J.6
  • 246
    • 0033971812 scopus 로고    scopus 로고
    • Histology and sensitivity to anticancer drugs of two human non-small cell lung carcinomas implanted in the pleural cavity of nude mice
    • L. Kraus-Berthier, M. Jan, N. Guilbaud, M. Naze, A. Pierre, and G. Atassi, Histology and sensitivity to anticancer drugs of two human non-small cell lung carcinomas implanted in the pleural cavity of nude mice. Clin. Cancer Res. 6, 297 (2000).
    • (2000) Clin. Cancer Res. , vol.6 , pp. 297
    • Kraus-Berthier, L.1    Jan, M.2    Guilbaud, N.3    Naze, M.4    Pierre, A.5    Atassi, G.6
  • 247
    • 0033025433 scopus 로고    scopus 로고
    • Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice
    • Y. Doki, K. Murakami, T. Yamaura, S. Sugiyama, T. Misaki, and I. Saiki, Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice. Br. J. Cancer 79, 1121 (1999).
    • (1999) Br. J. Cancer , vol.79 , pp. 1121
    • Doki, Y.1    Murakami, K.2    Yamaura, T.3    Sugiyama, S.4    Misaki, T.5    Saiki, I.6
  • 248
    • 0030795750 scopus 로고    scopus 로고
    • Establishment of an experimental intrapulmonary tumor nodule model
    • H. Y. Wang, H. M. Ross, B. Ng, and M. E. Burt, Establishment of an experimental intrapulmonary tumor nodule model. Ann. Thorac. Surg. 64, 216 (1997).
    • (1997) Ann. Thorac. Surg. , vol.64 , pp. 216
    • Wang, H.Y.1    Ross, H.M.2    Ng, B.3    Burt, M.E.4
  • 249
    • 0034070118 scopus 로고    scopus 로고
    • SCID mouse lymphogenous metastatic model of human lung cancer constructed using orthotopic inoculation of cancer cells
    • T. Miyoshi, K. Kondo, H. Ishikura, H. Kinoshita, Y. Matsumori, and Y. Monden, SCID mouse lymphogenous metastatic model of human lung cancer constructed using orthotopic inoculation of cancer cells. Anticancer Res. 20, 161 (2000).
    • (2000) Anticancer Res. , vol.20 , pp. 161
    • Miyoshi, T.1    Kondo, K.2    Ishikura, H.3    Kinoshita, H.4    Matsumori, Y.5    Monden, Y.6
  • 250
  • 251
    • 0022437977 scopus 로고
    • Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis
    • I. J. Fidler, Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis. Cancer Metastasis Rev. 5, 29 (1986).
    • (1986) Cancer Metastasis Rev. , vol.5 , pp. 29
    • Fidler, I.J.1
  • 252
    • 0026339998 scopus 로고
    • Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis
    • I. J. Fidler, Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis. Cancer Metastasis Rev. 10, 229 (1991).
    • (1991) Cancer Metastasis Rev. , vol.10 , pp. 229
    • Fidler, I.J.1
  • 253
    • 0025033870 scopus 로고
    • Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice
    • corrected
    • I. J. Fidler, S. Naito, and S. Pathak, Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice [corrected]. Cancer Metastasis Rev. 9, 149 (1990).
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 149
    • Fidler, I.J.1    Naito, S.2    Pathak, S.3
  • 254
    • 0345060457 scopus 로고    scopus 로고
    • Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice
    • A. Onn, T. Isobe, S. Itasaka, W. Wu, M. S. O'Reilly, W. Ki Hong, I. J. Fidler, and R. S. Herbst, Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clin. Cancer Res. 9, 5532 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , pp. 5532
    • Onn, A.1    Isobe, T.2    Itasaka, S.3    Wu, W.4    O'Reilly, M.S.5    Ki Hong, W.6    Fidler, I.J.7    Herbst, R.S.8
  • 255
    • 84893608874 scopus 로고    scopus 로고
    • Peptide-mediated liposomal Doxorubicin enhances drug delivery efficiency and therapeutic efficacy in animal models
    • D. K. Chang, P. C. Li, R. M. Lu, W. N. Jane, and H. C. Wu, Peptide-mediated liposomal Doxorubicin enhances drug delivery efficiency and therapeutic efficacy in animal models. PLoS One 8, 0083239 (2013).
    • (2013) PLoS One , vol.8 , pp. 0083239
    • Chang, D.K.1    Li, P.C.2    Lu, R.M.3    Jane, W.N.4    Wu, H.C.5
  • 259
    • 84881670536 scopus 로고    scopus 로고
    • Combinational delivery of c -myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy
    • Y. Zhang, L. Peng, R. J. Mumper, and L. Huang, Combinational delivery of c -myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy. Biomaterials 34, 8459 (2013).
    • (2013) Biomaterials , vol.34 , pp. 8459
    • Zhang, Y.1    Peng, L.2    Mumper, R.J.3    Huang, L.4
  • 260
    • 84881427940 scopus 로고    scopus 로고
    • Docetaxel conjugate nanoparticles that target alphasmooth muscle actin-expressing stromal cells suppress breast cancer metastasis
    • M. Murakami, M. J. Ernsting, E. Undzys, N. Holwell, W. D. Foltz and S. D. Li, Docetaxel conjugate nanoparticles that target alphasmooth muscle actin-expressing stromal cells suppress breast cancer metastasis. Cancer Res. 73, 4862 (2013).
    • (2013) Cancer Res. , vol.73 , pp. 4862
    • Murakami, M.1    Ernsting, M.J.2    Undzys, E.3    Holwell, N.4    Foltz, W.D.5    Li, S.D.6
  • 263
    • 0020680270 scopus 로고
    • The response to chemotherapy of a variety of human tumour xenografts
    • G. G. Steel, V. D. Courtenay, and M. J. Peckham, The response to chemotherapy of a variety of human tumour xenografts. Br. J. Cancer 47, 1 (1983).
    • (1983) Br. J. Cancer , vol.47 , pp. 1
    • Steel, G.G.1    Courtenay, V.D.2    Peckham, M.J.3
  • 266
    • 0020645067 scopus 로고
    • Gene transfer into mouse embryos: Production of transgenic mice by pronuclear injection
    • J. W. Gordon and F. H. Ruddle, Gene transfer into mouse embryos: Production of transgenic mice by pronuclear injection. Methods Enzymol. 101, 411 (1983).
    • (1983) Methods Enzymol. , vol.101 , pp. 411
    • Gordon, J.W.1    Ruddle, F.H.2
  • 267
    • 0018838586 scopus 로고
    • Retroviruses and embryogenesis: Microinjection of Moloney leukemia virus into midgestation mouse embryos
    • R. Jaenisch, Retroviruses and embryogenesis: Microinjection of Moloney leukemia virus into midgestation mouse embryos. Cell 19, 181 (1980).
    • (1980) Cell , vol.19 , pp. 181
    • Jaenisch, R.1
  • 268
    • 0019519189 scopus 로고
    • Chromosomal position and activation of retroviral genomes inserted into the germ line of mice
    • R. Jaenisch, D. Jahner, P. Nobis, I. Simon, J. Lohler, K. Harbers and D. Grotkopp, Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell 24, 519 (1981).
    • (1981) Cell , vol.24 , pp. 519
    • Jaenisch, R.1    Jahner, D.2    Nobis, P.3    Simon, I.4    Lohler, J.5    Harbers, K.6    Grotkopp, D.7
  • 269
    • 0019183519 scopus 로고
    • Integration of Moloney leukaemia virus into the germ line of mice: Correlation between site of integration and virus activation
    • D. Jahner and R. Jaenisch, Integration of Moloney leukaemia virus into the germ line of mice: Correlation between site of integration and virus activation. Nature 287, 456 (1980).
    • (1980) Nature , vol.287 , pp. 456
    • Jahner, D.1    Jaenisch, R.2
  • 270
    • 0022549490 scopus 로고
    • Retroviruses as probes for mammalian development: Allocation of cells to the somatic and germ cell lineages
    • P. Soriano and R. Jaenisch, Retroviruses as probes for mammalian development: Allocation of cells to the somatic and germ cell lineages. Cell 46, 19 (1986).
    • (1986) Cell , vol.46 , pp. 19
    • Soriano, P.1    Jaenisch, R.2
  • 271
    • 0035807255 scopus 로고    scopus 로고
    • Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene
    • R. Meuwissen, S. C. Linn, M. van der Valk, W. J. Mooi, and A. Berns, Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene. Oncogene 20, 6551 (2001).
    • (2001) Oncogene , vol.20 , pp. 6551
    • Meuwissen, R.1    Linn, S.C.2    Van Der Valk, M.3    Mooi, W.J.4    Berns, A.5
  • 273
    • 0024427595 scopus 로고
    • Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: Resistance to daunomycin-induced leukopenia
    • H. Galski, M. Sullivan, M. C. Willingham, K. V. Chin, M. M. Gottesman, I. Pastan, and G. T. Merlino, Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: Resistance to daunomycin-induced leukopenia. Mol. Cell Biol. 9, 4357 (1989).
    • (1989) Mol. Cell Biol. , vol.9 , pp. 4357
    • Galski, H.1    Sullivan, M.2    Willingham, M.C.3    Chin, K.V.4    Gottesman, M.M.5    Pastan, I.6    Merlino, G.T.7
  • 275
    • 0026673788 scopus 로고
    • Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice
    • K. A. Wikenheiser, J. C. Clark, R. I. Linnoila, M. T. Stahlman and J. A. Whitsett, Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice. Cancer Res. 52, 5342 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 5342
    • Wikenheiser, K.A.1    Clark, J.C.2    Linnoila, R.I.3    Stahlman, M.T.4    Whitsett, J.A.5


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