Magnetized aerosols comprising superparamagnetic iron oxide nanoparticles improve targeted drug and gene delivery to the lung

Pharmaceutical Research

Volumn 29, Issue 5, 2012, Pages 1308-1318

  Hasenpusch, Guenther ^a   Geiger, Johannes ^a   Wagner, Kai ^a   Mykhaylyk, Olga ^b   Wiekhorst, Frank ^c   Trahms, Lutz ^c   Heidsieck, Alexandra ^d   Gleich, Bernhard ^d   Bergemann, Christian ^e   Aneja, Manish K ^a   Rudolph, Carsten ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e Chemicell GmbH   (Germany)

Author keywords

Aerosol; Cancer; Gene delivery; Lung; Magnetic drug targeting

Indexed keywords

FLUORESCEIN SODIUM; PLASMID DNA; POLYETHYLENEIMINE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; VIRUS VECTOR;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BIOLUMINESCENCE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG TARGETING; EX VIVO STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE TRANSFER; GENE VECTOR; HISTOLOGY; IMAGE ANALYSIS; IMAGE DISPLAY; IN VIVO STUDY; ISOLATED LUNG; MAGNETIC FIELD; MOLECULAR WEIGHT; MOUSE; NEBULIZATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TRANSGENE;

AEROSOLS; ANIMALS; DRUG DELIVERY SYSTEMS; FEMALE; FERRIC COMPOUNDS; FLUORESCEIN; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LUNG; MAGNETICS; METAL NANOPARTICLES; MICE; MICE, INBRED BALB C; PLASMIDS; TRANSGENES;

EID: 84862700846     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0682-z     Document Type: Article

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