Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma

Biomaterials

Volumn 34, Issue 2, 2013, Pages 470-480

  Wang, Han ^a   Zheng, Linfeng ^a   Peng, Chen ^b   Shen, Mingwu ^b   Shi, Xiangyang ^b,c   Zhang, Guixiang ^a  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

^b DONGHUA UNIVERSITY   (China)

^c UNIVERSITY OF MADEIRA   (Portugal)

Author keywords

Computed tomography; Dendrimers; Folic acid; Gold nanoparticles; Lung adencarcinoma

Indexed keywords

CELL CYCLE; CELL MORPHOLOGY; CELL VIABILITY; COMPUTED TOMOGRAPHY; CONCENTRATION RANGES; CT IMAGING; FLOW-CYTOMETRIC ANALYSIS; FOLIC ACIDS; GOLD NANOPARTICLES; HUMAN LUNG; IMAGING PROBE; IMMUNOHISTOCHEMICAL STAINING; IN-VITRO; INTRAPERITONEAL ADMINISTRATION; LUNG ADENCARCINOMA; MICRO CT; MORPHOLOGICAL OBSERVATIONS; POLYAMIDOAMINE DENDRIMERS; TUMOR MODELS;

ACETYLATION; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; BROMINE COMPOUNDS; CELL DEATH; DENDRIMERS; GOLD; METAL NANOPARTICLES; NANOPROBES; ORGANIC ACIDS; RESPIRATORY SYSTEM; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

COMPUTERIZED TOMOGRAPHY;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMINE; DENDRIMER; EOSIN; FOLATE RECEPTOR; FOLIC ACID; GOLD NANOPARTICLE; HEMATOXYLIN;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; CELL ASSAY; CELL CYCLE; CELL STRUCTURE; CELL VIABILITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; COVALENT BOND; FLOW CYTOMETRY; HUMAN CELL CULTURE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG ADENOCARCINOMA; LYSOSOME; MALE; MOUSE; NANOPROBE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; DENDRIMERS; FOLIC ACID; GOLD; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84868194129     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.09.054     Document Type: Article

References (57)

1. Thakur M.L., Lentle B.C. Joint SNM/RSNA molecular imaging summit statement. J Nucl Med 2005, 46:11N-13N. 42N.
2. Weissleder R., Mahmood U. Molecular imaging. Radiology 2001, 219:316-333.
3. Mankoff D.A. A definition of molecular imaging. J Nucl Med 2007, 48:18N-21N.
4. Blankenberg F.G., Norfray J.F. Multimodality molecular imaging of apoptosis in oncology. Am J Roentgenol 2011, 197:308-317.
5. Haberkorn U., Markert A., Mier W., Askoxylakis V., Altmann A. Molecular imaging of tumor metabolism and apoptosis. Oncogene 2011, 30:4141-4151.
6. Heiss W.D., Raab P., Lanfermann H. Multimodality assessment of brain tumors and tumor recurrence. J Nucl Med 2011, 52:1585-1600.
7. Kashefi A., Kuo J., Shelton D.K. Molecular imaging in pulmonary diseases. Am J Roentgenol 2011, 197:295-307.
8. Kievit F.M., Zhang M. Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers. Adv Mater 2011, 23:H217-H247.
9. McCann T.E., Kosaka N., Turkbey B., Mitsunaga M., Choyke P.L., Kobayashi H. Molecular imaging of tumor invasion and metastases: the role of MRI. NMR Biomed 2011, 24:561-568.
10. Missbach-Guentner J., Hunia J., Alves F. Tumor blood vessel visualization. Int J Dev Biol 2011, 55:535-546.
11. New S.E., Aikawa E. Molecular imaging insights into early inflammatory stages of arterial and aortic valve calcification. Circ Res 2011, 108:1381-1391.
12. Ray P. Multimodality molecular imaging of disease progression in living subjects. J Biosci 2011, 36:499-504.
13. Raz D.J., Ray M.R., Kim J.Y., He B., Taron M., Skrzypski M., et al. A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma. Clin Cancer Res 2008, 14:5565-5570.
14. Sangodkar J., Katz S., Melville H., Narla G. Lung adenocarcinoma: lessons in translation from bench to bedside. Mt Sinai J Med 2010, 77:597-605.
15. Sun Y., Ren Y., Fang Z., Li C., Fang R., Gao B., et al. Lung adenocarcinoma from east asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol 2010, 28:4616-4620.
16. Yatabe Y., Borczuk A.C., Powell C.A. Do all lung adenocarcinomas follow a stepwise progression?. Lung Cancer 2011, 74:7-11.
17. Chen Y.C., Chen J.H., Richard K., Chen P.Y., Christiani D.C. Lung adenocarcinoma and human papillomavirus infection. Cancer 2004, 101:1428-1436.
18. Donington J.S., Koo C.W., Ballas M.S. Novel therapies for non-small cell lung cancer. J Thorac Imaging 2011, 26:175-185.
19. Ghosal R., Kloer P., Lewis K.E. A review of novel biological tools used in screening for the early detection of lung cancer. Postgrad Med J 2009, 85:358-363.
20. Indovina P., Marcelli E., Maranta P., Tarro G. Lung cancer proteomics: recent advances in biomarker discovery. Int J Proteomics 2011, 2011:726869.
21. Mellstedt H., Vansteenkiste J., Thatcher N. Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience. Lung Cancer 2011, 73:11-17.
22. Ahn S., Jung S.Y., Seo E., Lee S.J. Gold nanoparticle-incorporated human red blood cells (RBCs) for x-ray dynamic imaging. Biomaterials 2011, 32:7191-7199.
23. Kumar A., Ma H., Zhang X., Huang K., Jin S., Liu J., et al. Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment. Biomaterials 2012, 33:1180-1189.
24. Luo T., Huang P., Gao G., Shen G., Fu S., Cui D., et al. Mesoporous silica-coated gold nanorods with embedded indocyanine green for dual mode X-ray CT and NIR fluorescence imaging. Opt Express 2011, 19:17030-17039.
25. Peng C., Zheng L., Chen Q., Shen M., Guo R., Wang H., et al. PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography. Biomaterials 2012, 33:1107-1119.
26. Reuveni T., Motiei M., Romman Z., Popovtzer A., Popovtzer R. Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study. Int J Nanomedicine 2011, 6:2859-2864.
27. Wang H., Zheng L., Peng C., Guo R., Shen M., Shi X., et al. Computed tomography imaging of cancer cells using acetylated dendrimer-entrapped gold nanoparticles. Biomaterials 2011, 32:2979-2988.
28. Gao L., Cui Y., He Q., Yang Y., Fei J., Li J. Selective recognition of co-assembled thrombin aptamer and docetaxel on mesoporous silica nanoparticles against tumor cell proliferation. Chem Eur J 2011, 17:13170-13174.
29. Li D., He Q., Yang Y., Möhwald H., Li J. Two-stage pH response of poly(4-vinylpyridine) grafted gold nanoparticles. Macromolecules 2008, 41:7254-7256.
30. Li D., Li C., Wang A., He Q., Li J. Hierarchical gold/copolymer nanostructures as hydrophobic nanotanks for drug encapsulation. J Mater Chem 2010, 20:7782-7787.
31. Xia Y., Li W., Cobley C.M., Chen J., Xia X., Zhang Q., et al. Gold nanocages: from synthesis to theranostic applications. Acc Chem Res 2011, 44:914-924.
32. Connor E.E., Mwamuka J., Gole A., Murphy C.J., Wyatt M.D. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005, 1:325-327.
33. Shukla R., Bansal V., Chaudhary M., Basu A., Bhonde R.R., Sastry M. Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir 2005, 21:10644-10654.
34. Boisselier E., Astruc D. Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity. Chem Soc Rev 2009, 38:1759-1782.
35. Byrne J.D., Betancourt T., Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 2008, 60:1615-1626.
36. Marchal F., Pic E., Pons T., Dubertret B., Bolotine L., Guillemin F. Quantum dots in oncological surgery: the future for surgical margin status. Bull Cancer 2008, 95:1149-1153.
37. Patra C.R., Bhattacharya R., Mukhopadhyay D., Mukherjee P. Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer. Adv Drug Deliv Rev 2010, 62:346-361.
38. Popovtzer R., Agrawal A., Kotov N.A., Popovtzer A., Balter J., Carey T.E., et al. Targeted gold nanoparticles enable molecular CT imaging of cancer. Nano Lett 2008, 8:4593-4596.
39. Hainfeld J.F., Slatkin D.N., Focella T.M., Smilowitz H.M. Gold nanoparticles: a new X-ray contrast agent. Br J Radiol 2006, 79:248-253.
40. Hirsjarvi S., Passirani C., Benoit J.P. Passive and active tumour targeting with nanocarriers. Curr Drug Discov Technol 2011, 8:188-196.
41. Tomalia D.A., Frechet J.M.J. Dendrimers and other dendritic polymers 2001, John Wiley & Sons Ltd, New York.
42. Guo R., Wang H., Peng C., Shen M., Zheng L., Zhang G., et al. Enhanced x-ray attenuation property of dendrimer-entrapped gold nanoparticles complexed with diatrizoic acid. J Mater Chem 2011, 21:5120-5127.
43. Guo R., Wang H., Peng C., Shen M.W., Pan M.J., Cao X.Y., et al. X-ray attenuation property of dendrimer-entrapped gold nanoparticles. J Phys Chem C 2010, 114:50-56.
44. Kaminskas L.M., Porter C.J. Targeting the lymphatics using dendritic polymers (dendrimers). Adv Drug Deliv Rev 2011, 63:890-900.
45. Shi X., Wang S., Meshinchi S., Van Antwerp M.E., Bi X.D., Lee I.H., et al. Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging. Small 2007, 3:1245-1252.
46. Soliman G.M., Sharma A., Maysinger D., Kakkar A. Dendrimers and miktoarm polymers based multivalent nanocarriers for efficient and targeted drug delivery. Chem Commun (Camb) 2011, 47:9572-9587.
47. Majoros I.J., Myc A., Thomas T., Mehta C.B., Baker J.R. PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules 2006, 7:572-579.
48. Peng C., Wang H., Guo R., Shen M.W., Cao X.Y., Zhang G.X., et al. Acetylation of dendrimer-entrapped gold nanoparticles: synthesis, stability, and X-ray attenuation property. J Appl Polym Sci 2011, 119:1673-1682.
49. Franklin W.A., Waintrub M., Edwards D., Christensen K., Prendegrast P., Woods J., et al. New anti-lung-cancer antibody cluster 12 reacts with human folate receptors present on adenocarcinoma. Int J Cancer Suppl 1994, 8:89-95.
50. Qi W., Duan L., Li J. Fabrication of glucose-sensitive protein microcapsules and their applications. Soft Matter 2011, 7:1571-1576.
51. Qi W., Wang A., Yang Y., Du M., Bouchu M.N., Boullanger P., et al. The lectin binding and targetable cellular uptake of lipid-coated polysaccharide microcapsules. J Mater Chem 2010, 20:2121-2127.
52. Leamon C.P. Folate-targeted drug strategies for the treatment of cancer. Curr Opin Investig Drugs 2008, 9:1277-1286.
53. Sega E.I., Low P.S. Tumor detection using folate receptor-targeted imaging agents. Cancer Metastasis Rev 2008, 27:655-664.
54. Zhao X., Li H., Lee R.J. Targeted drug delivery via folate receptors. Expert Opin Drug Deliv 2008, 5:309-319.
55. Zhang Z.W., Jia J., Lai Y.Q., Ma Y.Y., Weng J.A., Sun L.P. Conjugating folic acid to gold nanoparticles through glutathione for targeting and detecting cancer cells. Bioorg Med Chem 2010, 18:5528-5534.
56. Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J Drug Target 2007, 15:457-464.
57. Yoo J.W., Chambers E., Mitragotri S. Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects. Curr Pharm Des 2010, 16:2298-2307.