Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation

Journal of Controlled Release

Volumn 144, Issue 2, 2010, Pages 221-226

  Mohri, Kohta ^a   Okuda, Tomoyuki ^a   Mori, Asami ^a   Danjo, Kazumi ^a   Okamoto, Hirokazu ^a  

^a MEIJO UNIVERSITY   (Japan)

Author keywords

Chitosan; Dry powder inhalers (DPI); In vivo imaging; Pulmonary gene delivery; Spray freeze drying (SFD)

Indexed keywords

DRY POWDER INHALER; FREEZE DRYING; IN-VIVO IMAGING; PULMONARY GENE DELIVERY; SPRAY-FREEZE DRYING (SFD);

ATOMIZERS; BIOLOGICAL ORGANS; CHITIN; CHITOSAN; CURING; ELECTRIC IMPEDANCE; ELECTROPHORESIS; GENE THERAPY; GENE TRANSFER; IMAGING TECHNIQUES; NUCLEIC ACIDS; PACKET NETWORKS; ROTATING MACHINERY;

GENE EXPRESSION;

CHITOSAN; PLASMID DNA;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG FORMULATION; DRY POWDER; ELECTROPHORESIS; FEMALE; FLUORESCENCE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; IN VIVO STUDY; LUMINESCENCE; LUNG; MORPHOLOGY; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ZETA POTENTIAL;

ADMINISTRATION, INHALATION; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DNA; DOSAGE FORMS; FEMALE; FREEZE DRYING; GENE THERAPY; GENES; LUNG; MICE; MICE, INBRED ICR; PLASMIDS; POWDERS; TRANSFECTION;

EID: 77952670572     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.02.018     Document Type: Article

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