Sequential targeted delivery of paclitaxel and camptothecin using a cross-linked "nanosponge" network for lung cancer chemotherapy

Molecular Pharmaceutics

Volumn 11, Issue 1, 2014, Pages 265-275

  Hariri, Ghazal ^a,b   Edwards, Aaron D ^a,b   Merrill, Tyler B ^a,b   Greenbaum, Joshua M ^a,b   Van Der Ende, Alice E ^a,b   Harth, Eva ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

camptothecin; combination therapy; metronomic chemotherapy; nanoparticle drug delivery; paclitaxel; sequential treatment

Indexed keywords

CAMPTOTHECIN; NANOCARRIER; NANOSPONGE; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG TUMOR LEVEL; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MALE; MASS SPECTROMETRY; MICROTUBULE; MICROVASCULAR ENDOTHELIAL CELL; MOLECULAR IMAGING; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CAMPTOTHECIN; CARCINOMA, LEWIS LUNG; CELL CYCLE; CELL PROLIFERATION; CROSS-LINKING REAGENTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PACLITAXEL; PEPTIDE FRAGMENTS; RADIATION, IONIZING; TUMOR CELLS, CULTURED;

EID: 84891786517     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400432b     Document Type: Article

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