Efficient down-regulation of PKC-α gene expression in A549 lung cancer cells mediated by antisense oligodeoxynucleotides in dendrosomes

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 82-91

  Movassaghian, Sara ^a,b   Moghimi, Hamid R ^a   Shirazi, Farshad H ^a   Koshkaryev, Alexander ^b   Trivedi, Malav S ^b   Torchilin, Vladimir P ^b  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Antisense oligodeoxynucleotides; Cancer gene delivery; Cytotoxicity; Dendrimer; Dendrosome; Liposome

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; LIPOSOME; MESSENGER RNA; NUCLEIC ACID; PROTEIN KINASE C ALPHA;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL ASSAY; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DENDROSOME; DOWN REGULATION; ENCAPSULATION; FLOW CYTOMETRY; FLUORESCENCE; GENE EXPRESSION; GENE VECTOR; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING; ZETA POTENTIAL;

BLOTTING, WESTERN; CELL LINE, TUMOR; DENDRIMERS; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; LIPOSOMES; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PROTEIN KINASE C-ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84872120013     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.015     Document Type: Article

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