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Volumn 32, Issue 3, 2001, Pages 265-279

Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ARTICLE; CANCER PREVENTION; CANCER RESEARCH; CANCER THERAPY; LUNG ADENOCARCINOMA; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0034997385     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(00)00232-4     Document Type: Article
Times cited : (106)

References (105)
  • 2
    • 0000243292 scopus 로고    scopus 로고
    • Epidemiology of the lung
    • H.I. Pass, J.B. Mitchell, D.H. Johnson, & A.T. Turrisi. Philadelphia, PA: Lippincott-Raven Press
    • Schottenfeld D. Epidemiology of the lung. Pass H.I., Mitchell J.B., Johnson D.H., Turrisi A.T. Lung Cancer: Principles and Practice. 1996;305-323 Lippincott-Raven Press, Philadelphia, PA.
    • (1996) Lung Cancer: Principles and Practice , pp. 305-323
    • Schottenfeld, D.1
  • 3
    • 0028176973 scopus 로고
    • Rising incidence of bronchioloalveolar lung carcinoma and its unique clinicopathologic features
    • Barsky S.H., Cameron R., Osann K.E., Tomita D., Holmes E.C. Rising incidence of bronchioloalveolar lung carcinoma and its unique clinicopathologic features. Cancer. 73:1994;1163-1179.
    • (1994) Cancer , vol.73 , pp. 1163-1179
    • Barsky, S.H.1    Cameron, R.2    Osann, K.E.3    Tomita, D.4    Holmes, E.C.5
  • 4
    • 0003557460 scopus 로고
    • Washington, DC: US Government Printing Office
    • Shimkin M.B. Contrary to Nature. 1979;US Government Printing Office, Washington, DC.
    • (1979) Contrary to Nature
    • Shimkin, M.B.1
  • 5
    • 0342359357 scopus 로고
    • Chemotherapy studies in human non-small cell lung cancer xenografts transplanted in immune-deprived mice
    • B. Winograd, M.J. Peckham, & H.M. Pinedo. New York: Springer
    • Carmichael J., Smyth J.F. Chemotherapy studies in human non-small cell lung cancer xenografts transplanted in immune-deprived mice. Winograd B., Peckham M.J., Pinedo H.M. Human Tumour Xenografts in Anticancer Drug Development. 1988;51-56 Springer, New York.
    • (1988) Human Tumour Xenografts in Anticancer Drug Development , pp. 51-56
    • Carmichael, J.1    Smyth, J.F.2
  • 6
    • 0342359359 scopus 로고
    • Fetal characteristics of cancer
    • Becker F.F. New York: Plenum
    • Uriel J.L. Fetal characteristics of cancer. Becker F.F. Cancer: a Comprehensive Treatise. 3:1975;21-56 Plenum, New York.
    • (1975) Cancer: A Comprehensive Treatise , vol.3 , pp. 21-56
    • Uriel, J.L.1
  • 8
    • 0005955559 scopus 로고    scopus 로고
    • Animal models in drug development
    • J.F. Holland, R.C. Jr. Bast, D.L. Morton, E. Frei, D.W. Kufe, Weichselbaum R.R. 4th edn Baltimore, MD: Williams & Wilkins
    • Khleif S.N., Curt G.A. Animal models in drug development. Holland J.F., Bast R.C. Jr, Morton D.L., Frei E., Kufe D.W., Weichselbaum R.R. 4th edn Cancer Medicine. 1:1997;855-868 Williams & Wilkins, Baltimore, MD.
    • (1997) Cancer Medicine , vol.1 , pp. 855-868
    • Khleif, S.N.1    Curt, G.A.2
  • 9
    • 0023893457 scopus 로고
    • Comparison of intrapulmonary, percutaneous intrathoracic and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice
    • McLemore T.L., Eggleston J.C., Shoemaker R.H., et al. Comparison of intrapulmonary, percutaneous intrathoracic and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice. Cancer Res. 48:1988;2880-2886.
    • (1988) Cancer Res. , vol.48 , pp. 2880-2886
    • McLemore, T.L.1    Eggleston, J.C.2    Shoemaker, R.H.3
  • 12
    • 0021242124 scopus 로고
    • Heterogeneity in a spontaneous mouse lung carcinoma: Selection and characterization of stable metastatic variants
    • Layton M.G., Franks L.M. Heterogeneity in a spontaneous mouse lung carcinoma: selection and characterization of stable metastatic variants. Brit. J. Cancer. 49:1984;415-421.
    • (1984) Brit. J. Cancer , vol.49 , pp. 415-421
    • Layton, M.G.1    Franks, L.M.2
  • 13
    • 0030101829 scopus 로고    scopus 로고
    • Inhibition of lung cancer proliferation by antisense cyclin D
    • Schrump D.S., Chen A., Consoli U. Inhibition of lung cancer proliferation by antisense cyclin D. Cancer Gene. Ther. 3:1996;131-135.
    • (1996) Cancer Gene. Ther. , vol.3 , pp. 131-135
    • Schrump, D.S.1    Chen, A.2    Consoli, U.3
  • 14
    • 0027317725 scopus 로고
    • Gap junctional intercellular communication in mouse lung epithelial cell lines: Effects of cell transformation and tumor promoters
    • Chaudhuri R.K., Sigler E., Dupont E., Trosko J.E., Malkinson A.M., Ruch R.J. Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters. Cancer Lett. 71:1993;11-18.
    • (1993) Cancer Lett. , vol.71 , pp. 11-18
    • Chaudhuri, R.K.1    Sigler, E.2    Dupont, E.3    Trosko, J.E.4    Malkinson, A.M.5    Ruch, R.J.6
  • 16
    • 0016634319 scopus 로고
    • Lung tumors in mice: Application in carcinogenesis bioassay
    • Shimkin M.B., Stoner G.D. Lung tumors in mice: application in carcinogenesis bioassay. Adv. Cancer Res. 21:1975;1-56.
    • (1975) Adv. Cancer Res. , vol.21 , pp. 1-56
    • Shimkin, M.B.1    Stoner, G.D.2
  • 17
    • 0024598143 scopus 로고
    • The genetic basis of susceptibility to lung tumors in mice
    • Malkinson A.M. The genetic basis of susceptibility to lung tumors in mice. Toxicology. 54:1989;241-271.
    • (1989) Toxicology , vol.54 , pp. 241-271
    • Malkinson, A.M.1
  • 18
    • 0017363609 scopus 로고
    • Enhancement of urethan tumorigenesis in mouse lung by butylated hydroxytoluene
    • Witschi H., Williamson D., Lock S. Enhancement of urethan tumorigenesis in mouse lung by butylated hydroxytoluene. J. Natl. Cancer Inst. 58:1977;301-305.
    • (1977) J. Natl. Cancer Inst. , vol.58 , pp. 301-305
    • Witschi, H.1    Williamson, D.2    Lock, S.3
  • 19
    • 0026764662 scopus 로고
    • Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids
    • You M., Wang Y., Stoner G., et al. Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. Proc. Natl. Acad. Sci. USA. 89:1992;5804-5808.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5804-5808
    • You, M.1    Wang, Y.2    Stoner, G.3
  • 20
    • 0030745488 scopus 로고    scopus 로고
    • Exposure to butylated hydroxytoluene is necessary for lung tumor development in BALB mice treated with low doses of 3-methylcholanthrene
    • Malkinson A.M., Koski K.M., Evans W.A., Festing M.F.W. Exposure to butylated hydroxytoluene is necessary for lung tumor development in BALB mice treated with low doses of 3-methylcholanthrene. Cancer Res. 57:1997;2832-2834.
    • (1997) Cancer Res. , vol.57 , pp. 2832-2834
    • Malkinson, A.M.1    Koski, K.M.2    Evans, W.A.3    Festing, M.F.W.4
  • 21
    • 0028805173 scopus 로고
    • Downregulation by butylated hydroxytoluene of the number and function of gap junctions in epithelial cell lines derived from mouse lung and rat liver
    • Guan X., Hardenbrook J., Fernstrom M.J., Chaudhuri R., Malkinson A.M., Ruch R.J. Downregulation by butylated hydroxytoluene of the number and function of gap junctions in epithelial cell lines derived from mouse lung and rat liver. Carcinogenesis. 16:1995;2575-2582.
    • (1995) Carcinogenesis , vol.16 , pp. 2575-2582
    • Guan, X.1    Hardenbrook, J.2    Fernstrom, M.J.3    Chaudhuri, R.4    Malkinson, A.M.5    Ruch, R.J.6
  • 22
    • 0032531133 scopus 로고    scopus 로고
    • Selective induction of apoptosis in mouse and human lung epithelial cell lines by the tert- butyl hydroxylated metabolite of butylated hydroxytoluene: A proposed role in tumor promotion
    • Dwyer-Nield L.D., Thompson J.A., Peljak G., et al. Selective induction of apoptosis in mouse and human lung epithelial cell lines by the tert- butyl hydroxylated metabolite of butylated hydroxytoluene: a proposed role in tumor promotion. Toxicology. 130:1998;115-127.
    • (1998) Toxicology , vol.130 , pp. 115-127
    • Dwyer-Nield, L.D.1    Thompson, J.A.2    Peljak, G.3
  • 23
    • 0028358722 scopus 로고
    • Strain-related differences in the pneumotoxic effects of chronically-administered butylated hydroxytoluene on protein kinase C and calpain
    • Miller A.C.K., Dwyer L.D., Auerbach C.E., Miley F.B., Dinsdale D., Malkinson A.M. Strain-related differences in the pneumotoxic effects of chronically-administered butylated hydroxytoluene on protein kinase C and calpain. Toxicology. 90:1994;141-159.
    • (1994) Toxicology , vol.90 , pp. 141-159
    • Miller, A.C.K.1    Dwyer, L.D.2    Auerbach, C.E.3    Miley, F.B.4    Dinsdale, D.5    Malkinson, A.M.6
  • 24
    • 0018903446 scopus 로고
    • Generation of oncogenic mouse type C viruses: In vitro selection of carcinoma-inducing variants
    • Rapp U.R., Todaro G.J. Generation of oncogenic mouse type C viruses: in vitro selection of carcinoma-inducing variants. Proc. Natl. Acad. Sci. USA. 77:1980;624-628.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 624-628
    • Rapp, U.R.1    Todaro, G.J.2
  • 25
    • 0032899916 scopus 로고    scopus 로고
    • Jaagsiekte retrovirus establishes a pantropic infection of lymphoid cells of sheep with naturally and experimentally acquired pulmonary adenomatosis
    • Holland M.J., Palmarini M., Garcia-Goti M., Gonzalez L., de las Heras M., Sharp J.M. Jaagsiekte retrovirus establishes a pantropic infection of lymphoid cells of sheep with naturally and experimentally acquired pulmonary adenomatosis. J. Virol. 73:1999;4004-4008.
    • (1999) J. Virol. , vol.73 , pp. 4004-4008
    • Holland, M.J.1    Palmarini, M.2    Garcia-Goti, M.3    Gonzalez, L.4    De Las Heras, M.5    Sharp, J.M.6
  • 26
    • 0002222672 scopus 로고    scopus 로고
    • Transgenic mice for study of pulmonary disease
    • R.G. Crystal, J.B. West, E.R. Weibel, Barnes P.J. Philadelphia, PA: Lippincott-Raven Press
    • Whitsett J.A., Gerard C. Transgenic mice for study of pulmonary disease. Crystal R.G., West J.B., Weibel E.R., Barnes P.J. The Lung. 1:1997;383-394 Lippincott-Raven Press, Philadelphia, PA.
    • (1997) The Lung , vol.1 , pp. 383-394
    • Whitsett, J.A.1    Gerard, C.2
  • 27
    • 0014506645 scopus 로고
    • Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens
    • Shimkin M.B., Sasaki T., McDonough M., Baserga R., Thatcher D., Weider R. Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens. Cancer Res. 29:1969;994-998.
    • (1969) Cancer Res. , vol.29 , pp. 994-998
    • Shimkin, M.B.1    Sasaki, T.2    McDonough, M.3    Baserga, R.4    Thatcher, D.5    Weider, R.6
  • 29
    • 0342359356 scopus 로고
    • Some quantitative observations on the induction and growth of primary pulmonary tumors in strain A mice receiving urethane
    • Shimkin M.B., Polissar M.J. Some quantitative observations on the induction and growth of primary pulmonary tumors in strain A mice receiving urethane. J. Natl. Cancer Inst. 16:1955;75-97.
    • (1955) J. Natl. Cancer Inst. , vol.16 , pp. 75-97
    • Shimkin, M.B.1    Polissar, M.J.2
  • 30
    • 0026652576 scopus 로고
    • Primary lung tumors in mice: An experimentally manipulable model of human adenocarcinoma
    • Malkinson A.M. Primary lung tumors in mice: an experimentally manipulable model of human adenocarcinoma. Cancer Res. 52:1992;2670s-2676s.
    • (1992) Cancer Res. , vol.52
    • Malkinson, A.M.1
  • 31
    • 84959820345 scopus 로고
    • Genetic analysis of susceptibility to induced pulmonary tumors in mice
    • Heston W.E. Genetic analysis of susceptibility to induced pulmonary tumors in mice. J. Natl. Cancer Inst. 3:1942;69-78.
    • (1942) J. Natl. Cancer Inst. , vol.3 , pp. 69-78
    • Heston, W.E.1
  • 32
    • 0009484021 scopus 로고
    • The biological behavior of transplacentally induced tumors in mice
    • L. Tomatis, & U. Mohr. Lyon: IARC Scientific
    • Rice J.M. The biological behavior of transplacentally induced tumors in mice. Tomatis L., Mohr U. Transplacental Carcinogenesis. 1973;14-22 IARC Scientific, Lyon.
    • (1973) Transplacental Carcinogenesis , pp. 14-22
    • Rice, J.M.1
  • 34
    • 0030818561 scopus 로고    scopus 로고
    • Genetic mapping of lung cancer modifier loci specifically affecting tumor initiation and progression
    • Manenti G., Gariboldi M., Fiorino A., Zanesi N.L., Pierottti M.A., Dragani T.A. Genetic mapping of lung cancer modifier loci specifically affecting tumor initiation and progression. Cancer Res. 57:1997;4164-4166.
    • (1997) Cancer Res. , vol.57 , pp. 4164-4166
    • Manenti, G.1    Gariboldi, M.2    Fiorino, A.3    Zanesi, N.L.4    Pierottti, M.A.5    Dragani, T.A.6
  • 35
    • 0026318874 scopus 로고
    • Lung tumor structure among inbred strains of mice: The pulmonary adenoma hisologic type (Pah) genes
    • Thaete L.G., Nesbitt M.N., Malkinson A.M. Lung tumor structure among inbred strains of mice: the pulmonary adenoma hisologic type (Pah) genes. Cancer Lett. 61:1991;15-20.
    • (1991) Cancer Lett. , vol.61 , pp. 15-20
    • Thaete, L.G.1    Nesbitt, M.N.2    Malkinson, A.M.3
  • 36
    • 0023185649 scopus 로고
    • Cellular derivation of lung tumors in sensitive and resistant strains of mice: Results at twenty-eight and fifty-six weeks after urethan treatment
    • Thaete L.G., Gunning W.T., Stoner G.D., Malkinson A.M. Cellular derivation of lung tumors in sensitive and resistant strains of mice: results at twenty-eight and fifty-six weeks after urethan treatment. J. Natl. Cancer Inst. 78:1987;7434-7439.
    • (1987) J. Natl. Cancer Inst. , vol.78 , pp. 7434-7439
    • Thaete, L.G.1    Gunning, W.T.2    Stoner, G.D.3    Malkinson, A.M.4
  • 37
    • 0023841284 scopus 로고
    • Effect of gestational development on lung tumor size and morphology in the mouse
    • Branstetter D.G., Stoner G.D., Budd C., Conran P.B., Goldblatt P.J. Effect of gestational development on lung tumor size and morphology in the mouse. Cancer Res. 48:1988;379-386.
    • (1988) Cancer Res. , vol.48 , pp. 379-386
    • Branstetter, D.G.1    Stoner, G.D.2    Budd, C.3    Conran, P.B.4    Goldblatt, P.J.5
  • 38
    • 0026042284 scopus 로고
    • Genetic studies on lung tumor susceptibility and histogenesis in mice
    • Malkinson A.M. Genetic studies on lung tumor susceptibility and histogenesis in mice. Environ. Hlth. Perspect. 93:1991;149-159.
    • (1991) Environ. Hlth. Perspect. , vol.93 , pp. 149-159
    • Malkinson, A.M.1
  • 39
  • 40
    • 0025298188 scopus 로고
    • Differential staining of normal and neoplastic mouse lung epithelia by succinate dehydrogenase histochemistry
    • Thaete L.G., Malkinson A.M. Differential staining of normal and neoplastic mouse lung epithelia by succinate dehydrogenase histochemistry. Cancer Lett. 52:1990;219-227.
    • (1990) Cancer Lett. , vol.52 , pp. 219-227
    • Thaete, L.G.1    Malkinson, A.M.2
  • 41
    • 0026071368 scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase and other enzymatic activity in normal mouse lung and in lung tumors
    • Gunning W.T., Stoner G.S., Goldblatt P.J. Glyceraldehyde-3-phosphate dehydrogenase and other enzymatic activity in normal mouse lung and in lung tumors. Exp. Lung Res. 17:1991;255-262.
    • (1991) Exp. Lung Res. , vol.17 , pp. 255-262
    • Gunning, W.T.1    Stoner, G.S.2    Goldblatt, P.J.3
  • 42
    • 0006550088 scopus 로고    scopus 로고
    • Topography of preneoplasia: Morphology and markers
    • M.A. Kane, & P.A. Bunn. New York: Marcel Dekker
    • Linnoila I. Topography of preneoplasia: morphology and markers. Kane M.A., Bunn P.A. Biology of Lung Cancer. 1998;503-528 Marcel Dekker, New York.
    • (1998) Biology of Lung Cancer , pp. 503-528
    • Linnoila, I.1
  • 43
    • 0026673788 scopus 로고
    • Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice
    • Wikenheiser K.A., Clark J.C., Linnoila L., Stahlman M.T., Whitsett J.A. Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice. Cancer Res. 52:1992;5342-5352.
    • (1992) Cancer Res. , vol.52 , pp. 5342-5352
    • Wikenheiser, K.A.1    Clark, J.C.2    Linnoila, L.3    Stahlman, M.T.4    Whitsett, J.A.5
  • 44
    • 0343664535 scopus 로고    scopus 로고
    • Evolutionary model of lung cancer
    • H.I. Pass, J.B. Mitchell, D.H. Johnson, & A.T. Turrisi. Philadelphia, PA: Lippincott-Raven Press
    • Mabry M., Nelkin B.S., Baylin S.B. Evolutionary model of lung cancer. Pass H.I., Mitchell J.B., Johnson D.H., Turrisi A.T. Lung Cancer: Principles and Practice. 1996;133-142 Lippincott-Raven Press, Philadelphia, PA.
    • (1996) Lung Cancer: Principles and Practice , pp. 133-142
    • Mabry, M.1    Nelkin, B.S.2    Baylin, S.B.3
  • 45
    • 0028346371 scopus 로고
    • Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum free conditions
    • Siegfried J., Hong Han Y., DeMichele M.A.A. Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum free conditions. J. Biol. Chem. 269:1994;8596-8603.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8596-8603
    • Siegfried, J.1    Hong Han, Y.2    Demichele, M.A.A.3
  • 46
    • 4243644282 scopus 로고    scopus 로고
    • Calcitionin driven v-Ha-ras induces pulmonary neuroendocrine (NE) and non-NE neoplasms
    • Sunday M.E., Sikorsky K., Zhang F., Hatzis D. Calcitionin driven v-Ha-ras induces pulmonary neuroendocrine (NE) and non-NE neoplasms. Lab. Invest. 78:1998;166A.
    • (1998) Lab. Invest. , vol.78
    • Sunday, M.E.1    Sikorsky, K.2    Zhang, F.3    Hatzis, D.4
  • 47
    • 0004845577 scopus 로고    scopus 로고
    • Ras and erbb2
    • In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, Minna JD, editors. Philadelphia, PA: Lippincott Willliams & Wilkins
    • Lechner JF, Fugaro JM,. Ras and erbb2. In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, Minna JD, editors. Lung Cancer: Principles and Practice. 2nd edn., Philadelphia, PA: Lippincott Willliams & Wilkins, 2000:89-97.
    • (2000) Lung Cancer: Principles and Practice. 2nd Edn. , pp. 89-97
    • Lechner, J.F.1    Fugaro, J.M.2
  • 48
    • 0028245344 scopus 로고
    • Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice
    • Li E.E., Heflich H., Bucci T.J., Manjanatha M.G., Blaydes B.S., Delclos K.B. Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice. Carcinogenesis. 15:1994;1377-1385.
    • (1994) Carcinogenesis , vol.15 , pp. 1377-1385
    • Li, E.E.1    Heflich, H.2    Bucci, T.J.3    Manjanatha, M.G.4    Blaydes, B.S.5    Delclos, K.B.6
  • 49
    • 0032697597 scopus 로고    scopus 로고
    • Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methlycholanthrene and postnatally exposed to butylated hydroxytoluene
    • Gressani K.M., Leone-Kabler S., O'Sullivan G., Case L.D., Malkinson A.M., Miller M.S. Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methlycholanthrene and postnatally exposed to butylated hydroxytoluene. Carcinogenesis. 20:1999;2159-2165.
    • (1999) Carcinogenesis , vol.20 , pp. 2159-2165
    • Gressani, K.M.1    Leone-Kabler, S.2    O'Sullivan, G.3    Case, L.D.4    Malkinson, A.M.5    Miller, M.S.6
  • 50
    • 0027292743 scopus 로고
    • Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors
    • Chen B., Liu L., Castonguay A., Maronpot R.R., Anderson M.W., You M. Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. Carcinogenesis. 14:1993;1603-1608.
    • (1993) Carcinogenesis , vol.14 , pp. 1603-1608
    • Chen, B.1    Liu, L.2    Castonguay, A.3    Maronpot, R.R.4    Anderson, M.W.5    You, M.6
  • 51
    • 14444278728 scopus 로고    scopus 로고
    • Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene
    • Lin L., Festing M.F.W., Devereux T.R., Crist K.A., Christiansen S.C., Wang Y., et al. Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene. Exp. Lung Res. 24:1998;481-498.
    • (1998) Exp. Lung Res. , vol.24 , pp. 481-498
    • Lin, L.1    Festing, M.F.W.2    Devereux, T.R.3    Crist, K.A.4    Christiansen, S.C.5    Wang, Y.6
  • 52
    • 0025670013 scopus 로고
    • Specific K-ras codon 61 mutations may determine the development of mouse lung adenomas or adenocarcinomas
    • Nuzum E.O., Malkinson A.M., Beer D.G. Specific K-ras codon 61 mutations may determine the development of mouse lung adenomas or adenocarcinomas. Molec. Carcinogen. 3:1990;287-295.
    • (1990) Molec. Carcinogen. , vol.3 , pp. 287-295
    • Nuzum, E.O.1    Malkinson, A.M.2    Beer, D.G.3
  • 54
    • 0030006213 scopus 로고    scopus 로고
    • Increased cytosine DNA-methyltransferase activity is target cell-specific and an early event in lung cancer
    • Belinsky S.A., Nikula K.J., Baylin S.B., Issa J.P.J. Increased cytosine DNA-methyltransferase activity is target cell-specific and an early event in lung cancer. Proc. Natl. Acad. Sci. USA. 93:1996;4045-4050.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4045-4050
    • Belinsky, S.A.1    Nikula, K.J.2    Baylin, S.B.3    Issa, J.P.J.4
  • 55
    • 0031804606 scopus 로고    scopus 로고
    • Molecular changes during the development of pulmonary adenocarcinomas in mouse and man: A comparison
    • Malkinson A.M. Molecular changes during the development of pulmonary adenocarcinomas in mouse and man: a comparison. Exp. Lung Res. 24:1998;541-546.
    • (1998) Exp. Lung Res. , vol.24 , pp. 541-546
    • Malkinson, A.M.1
  • 56
    • 0030453289 scopus 로고    scopus 로고
    • K-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice
    • Horio Y.L., Schrump D.S., Chen A., Rice P., Malkinson A.M., Roth J.A. K-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. Molec. Carcinogen. 16:1996;217-223.
    • (1996) Molec. Carcinogen. , vol.16 , pp. 217-223
    • Horio, Y.L.1    Schrump, D.S.2    Chen, A.3    Rice, P.4    Malkinson, A.M.5    Roth, J.A.6
  • 57
    • 0342359354 scopus 로고    scopus 로고
    • Specific chromosomal changes in mouse lung adenocarcinoma cell lines detected by spectral karyotyping
    • In press
    • Sargent LM, Senft JR, Lowry DT, et al. Specific chromosomal changes in mouse lung adenocarcinoma cell lines detected by spectral karyotyping. Proc Am Assoc Cancer Res In press.
    • Proc Am Assoc Cancer Res
    • Sargent, L.M.1    Senft, J.R.2    Lowry, D.T.3
  • 58
    • 0032781269 scopus 로고    scopus 로고
    • Reduced receptor expression for platelet-derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells
    • Rice P.L., Porter S.E., Koski K.M., et al. Reduced receptor expression for platelet-derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells. Molec. Carcinogen. 25:1999;285-294.
    • (1999) Molec. Carcinogen. , vol.25 , pp. 285-294
    • Rice, P.L.1    Porter, S.E.2    Koski, K.M.3
  • 59
    • 0026700546 scopus 로고
    • Elevated DT-diaphorase activity and mRNA content in human non-small cell lung carcinoma: Relationship to the response of lung tumor xenografts to mitomycin C
    • Malkinson A.M., Siegel D., Forrest G.L., et al. Elevated DT-diaphorase activity and mRNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin C. Cancer Res. 52:1992;4752-4757.
    • (1992) Cancer Res. , vol.52 , pp. 4752-4757
    • Malkinson, A.M.1    Siegel, D.2    Forrest, G.L.3
  • 60
    • 0025744892 scopus 로고
    • NAD(P)H: Quinone oxidoreductase (DT-diaphorase) activities in normal and neoplastic mouse lung epithelia
    • Thaete L.G., Siegel D., Malkinson A.M., Ross D. NAD(P)H: quinone oxidoreductase (DT-diaphorase) activities in normal and neoplastic mouse lung epithelia. Int. J. Cancer. 49:1991;145-149.
    • (1991) Int. J. Cancer , vol.49 , pp. 145-149
    • Thaete, L.G.1    Siegel, D.2    Malkinson, A.M.3    Ross, D.4
  • 61
    • 0004842293 scopus 로고
    • A single gene in BALB/cBy mice with a major effect on susceptibility to urethane-induced pulmonary adenoma
    • Malkinson A.M., Beer D.S. A single gene in BALB/cBy mice with a major effect on susceptibility to urethane-induced pulmonary adenoma. J. Natl. Cancer Inst. 70:1983;981-986.
    • (1983) J. Natl. Cancer Inst. , vol.70 , pp. 981-986
    • Malkinson, A.M.1    Beer, D.S.2
  • 62
    • 0032612604 scopus 로고    scopus 로고
    • Inheritance of pulmonary adenoma susceptibility in mice
    • Malkinson A.M. Inheritance of pulmonary adenoma susceptibility in mice. Prog. Exp. Tumor. Res. 35:1999;78-94.
    • (1999) Prog. Exp. Tumor. Res. , vol.35 , pp. 78-94
    • Malkinson, A.M.1
  • 63
    • 0026764662 scopus 로고
    • Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids
    • You M., Wang Y., Stoner G., et al. Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. Proc. Natl. Acad. Sci. USA. 89:1992;5804-5808.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5804-5808
    • You, M.1    Wang, Y.2    Stoner, G.3
  • 64
    • 0023605863 scopus 로고
    • KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice
    • Ryan J., Barker P.E., Nesbitt M.N., Ruddle F.H. KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice. J. Natl. Cancer Inst. 79:1985;1351-1357.
    • (1985) J. Natl. Cancer Inst. , vol.79 , pp. 1351-1357
    • Ryan, J.1    Barker, P.E.2    Nesbitt, M.N.3    Ruddle, F.H.4
  • 65
    • 0027450846 scopus 로고
    • A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6
    • Gariboldi M., Manenti G., Canzian F., et al. A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6. Nature Genet. 3:1993;132-136.
    • (1993) Nature Genet. , vol.3 , pp. 132-136
    • Gariboldi, M.1    Manenti, G.2    Canzian, F.3
  • 66
    • 0028067023 scopus 로고
    • The intronic structure of cancer-related genes regulates susceptibility to cancer
    • Malkinson A.M., You M. The intronic structure of cancer-related genes regulates susceptibility to cancer. Molec. Carcinogen. 10:1994;61-65.
    • (1994) Molec. Carcinogen. , vol.10 , pp. 61-65
    • Malkinson, A.M.1    You, M.2
  • 67
    • 0027979481 scopus 로고
    • Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens
    • Chen B., Johanson L., Wiest J.S., Anderson M.W., You M. Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens. Proc. Natl. Acad. Sci. USA. 91:1994;1589-1593.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1589-1593
    • Chen, B.1    Johanson, L.2    Wiest, J.S.3    Anderson, M.W.4    You, M.5
  • 68
    • 0032993060 scopus 로고    scopus 로고
    • Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis
    • Herzog C.R., Noh S., Lantry L.E., Guan K.-L., You M. Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis. Molec. Carcinogen. 25:1999;92-98.
    • (1999) Molec. Carcinogen. , vol.25 , pp. 92-98
    • Herzog, C.R.1    Noh, S.2    Lantry, L.E.3    Guan, K.-L.4    You, M.5
  • 70
    • 0029011728 scopus 로고
    • Previous lung disease and risk of lung cancer among lifetime nonsmoking women in the United States
    • Wu A.H., Fontham E.T., Reynold P., et al. Previous lung disease and risk of lung cancer among lifetime nonsmoking women in the United States. Am. J. Epidemiol. 141:1995;1023-1032.
    • (1995) Am. J. Epidemiol. , vol.141 , pp. 1023-1032
    • Wu, A.H.1    Fontham, E.T.2    Reynold, P.3
  • 71
    • 0031417629 scopus 로고    scopus 로고
    • Association of chromosome 12p genetic polymorphisms with lung adenocarcinoma risk and prognosis
    • Manenti G., De Gregorio L., Pilotti S., et al. Association of chromosome 12p genetic polymorphisms with lung adenocarcinoma risk and prognosis. Carcinogenesis. 18:1997;1917-1920.
    • (1997) Carcinogenesis , vol.18 , pp. 1917-1920
    • Manenti, G.1    De Gregorio, L.2    Pilotti, S.3
  • 72
    • 0034665132 scopus 로고    scopus 로고
    • Population-based mapping of pulmonary adenoma susceptibility 1 locus
    • Dragani T.A., Hirohashi S., Juji T., et al. Population-based mapping of pulmonary adenoma susceptibility 1 locus. Cancer Res. 60:2000;5017-5020.
    • (2000) Cancer Res. , vol.60 , pp. 5017-5020
    • Dragani, T.A.1    Hirohashi, S.2    Juji, T.3
  • 73
    • 0017136711 scopus 로고
    • Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)
    • Sporn M.B., Dunlop N.M., Newton D.L., Smith J.M. Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed. Proc. 35:1976;1332-1338.
    • (1976) Fed. Proc. , vol.35 , pp. 1332-1338
    • Sporn, M.B.1    Dunlop, N.M.2    Newton, D.L.3    Smith, J.M.4
  • 74
    • 0030331466 scopus 로고    scopus 로고
    • The role of chemoprevention in cancer control
    • B.W. Stewart, D. McGregor, & P. Kleihues. Lyon: IARC Scientific
    • Greenwald P., Kelloff G.J. The role of chemoprevention in cancer control. Stewart B.W., McGregor D., Kleihues P. Principles of Chemoprevention. 1996;13-22 IARC Scientific, Lyon.
    • (1996) Principles of Chemoprevention , pp. 13-22
    • Greenwald, P.1    Kelloff, G.J.2
  • 75
    • 0021934758 scopus 로고
    • Chemoprevention of cancer
    • Wattenberg L.W. Chemoprevention of cancer. Cancer Res. 45:1985;1-8.
    • (1985) Cancer Res. , vol.45 , pp. 1-8
    • Wattenberg, L.W.1
  • 76
    • 0030332480 scopus 로고    scopus 로고
    • Mechanistic considerations in the evaluation of chemopreventive data
    • B.W. Stewart, D. McGregor, & P. Kleihues. Lyon: IARC Scientific
    • Kelloff G.J., Boone C.W., Steele V.E., et al. Mechanistic considerations in the evaluation of chemopreventive data. Stewart B.W., McGregor D., Kleihues P. Principles of Chemoprevention. 1996;203-220 IARC Scientific, Lyon.
    • (1996) Principles of Chemoprevention , pp. 203-220
    • Kelloff, G.J.1    Boone, C.W.2    Steele, V.E.3
  • 77
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med, 1994;330:1029-1035.
    • (1994) N Engl J Med , vol.330 , pp. 1029-1035
  • 78
    • 0026762516 scopus 로고
    • Chemoprevention strategies for lung and upper aerodigestive tract cancer
    • Benner S.E., Lippman S.M., Hong W.K. Chemoprevention strategies for lung and upper aerodigestive tract cancer. Cancer Res. 52:1992;2757s-2763s.
    • (1992) Cancer Res. , vol.52
    • Benner, S.E.1    Lippman, S.M.2    Hong, W.K.3
  • 79
    • 0031328735 scopus 로고    scopus 로고
    • Tea antioxidants in cancer chemoprevention,
    • Katiyar S.K., Mukhtar H. Tea antioxidants in cancer chemoprevention, , J. Cell. Biochem. 27:((Suppl)):1997;59-67.
    • (1997) J. Cell. Biochem. , vol.27 , Issue.SUPPL , pp. 59-67
    • Katiyar, S.K.1    Mukhtar, H.2
  • 80
    • 0026635436 scopus 로고
    • Inhibition of N-nitrosodiethylamine- And 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in A/J mice by green tea and black tea
    • Wang Z.Y., Hong J.Y., Huang M.-T., Reuhl K.R., Conney A.H., Yang C.S. Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in A/J mice by green tea and black tea. Cancer Res. 52:1992;1943-1947.
    • (1992) Cancer Res. , vol.52 , pp. 1943-1947
    • Wang, Z.Y.1    Hong, J.Y.2    Huang, M.-T.3    Reuhl, K.R.4    Conney, A.H.5    Yang, C.S.6
  • 81
    • 0031324902 scopus 로고    scopus 로고
    • Chemopreventive effect of green tea (Camellia sinensis) against cigarette smoke-induced mutations (SCE) in humans
    • Lee I.P., Kim Y.H., Kang M.H., Roberts C., Shim J.S., Roh J.K. Chemopreventive effect of green tea (Camellia sinensis) against cigarette smoke-induced mutations (SCE) in humans. J. Cell. Biochem. 27:(Suppl):1997;68-75.
    • (1997) J. Cell. Biochem. , vol.27 , Issue.SUPPL , pp. 68-75
    • Lee, I.P.1    Kim, Y.H.2    Kang, M.H.3    Roberts, C.4    Shim, J.S.5    Roh, J.K.6
  • 82
    • 0030754664 scopus 로고    scopus 로고
    • Approaches to chemoprevention of lung cancer based on carcinogens in tobacco smoke
    • Hecht S.S. Approaches to chemoprevention of lung cancer based on carcinogens in tobacco smoke. Environ. Hlth. Perspect. 105:(Suppl 4):1997;955-964.
    • (1997) Environ. Hlth. Perspect. , vol.105 , Issue.SUPPL. 4 , pp. 955-964
    • Hecht, S.S.1
  • 83
    • 0031313611 scopus 로고    scopus 로고
    • Chemopreventive potential of thiol conjugates of isothiocyanates for lung cancer and a urinary biomarker of dietary isothiocyanates,
    • Chung F.-L., Jiao D., Conaway C.C., Smith T.J., Yang C.S., Yu M.C. Chemopreventive potential of thiol conjugates of isothiocyanates for lung cancer and a urinary biomarker of dietary isothiocyanates, , J. Cell. Biochem. 27:(Suppl):1997;76-85.
    • (1997) J. Cell. Biochem. , vol.27 , Issue.SUPPL , pp. 76-85
    • Chung, F.-L.1    Jiao, D.2    Conaway, C.C.3    Smith, T.J.4    Yang, C.S.5    Yu, M.C.6
  • 84
    • 0034718294 scopus 로고    scopus 로고
    • Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China
    • London S.J., Yuan J.-M., Chung F.-L., et al. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China. Lancet. 356:2000;724-729.
    • (2000) Lancet , vol.356 , pp. 724-729
    • London, S.J.1    Yuan, J.-M.2    Chung, F.-L.3
  • 85
    • 0022913249 scopus 로고
    • Regulation of pulmonary surfactant apoprotein SP 28-36 gene in fetal human lung
    • Ballard P.L., Hawgood S., Liley H., et al. Regulation of pulmonary surfactant apoprotein SP 28-36 gene in fetal human lung. Proc. Natl. Acad. Sci. USA. 83:1986;9527-9531.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9527-9531
    • Ballard, P.L.1    Hawgood, S.2    Liley, H.3
  • 86
    • 0024566951 scopus 로고
    • Glucocorticoid hormone effect on transplacental carcinogenesis and lung differentiation: Influence of histocompatibility-2 (H-2) complex
    • Oomen L.C.J.M., Valk M.A., Hart A.A., Demant P. Glucocorticoid hormone effect on transplacental carcinogenesis and lung differentiation: influence of histocompatibility-2 (H-2) complex. J. Natl. Cancer Inst. 81:1989;512-517.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 512-517
    • Oomen, L.C.J.M.1    Valk, M.A.2    Hart, A.A.3    Demant, P.4
  • 87
    • 0023908110 scopus 로고
    • Effects of adrenalectomy and corticosterone administration on mouse lung tumor susceptibility and histogenesis
    • Droms K.A., Fernandez C.A., Thaete L.G., Malkinson A.M. Effects of adrenalectomy and corticosterone administration on mouse lung tumor susceptibility and histogenesis. J. Natl. Cancer Inst. 80:1988;365-369.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 365-369
    • Droms, K.A.1    Fernandez, C.A.2    Thaete, L.G.3    Malkinson, A.M.4
  • 89
    • 0031416517 scopus 로고    scopus 로고
    • Chemopreventive efficacies of aspirin and sulindac against lung tumorigenesis in A/J mice
    • Duperron C., Castonguay A. Chemopreventive efficacies of aspirin and sulindac against lung tumorigenesis in A/J mice. Carcinogenesis. 18:1997;1001-1006.
    • (1997) Carcinogenesis , vol.18 , pp. 1001-1006
    • Duperron, C.1    Castonguay, A.2
  • 90
    • 0029035070 scopus 로고
    • Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis
    • Piazza G.A., Kulchak-Rahm A.L., Krutzch M. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Cancer Res. 55:1995;3110-3116.
    • (1995) Cancer Res. , vol.55 , pp. 3110-3116
    • Piazza, G.A.1    Kulchak-Rahm, A.L.2    Krutzch, M.3
  • 91
    • 0031661654 scopus 로고    scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumor formation by FGN-1 (sulindac sulfone)
    • Malkinson A.M., Koski K.M., Dwyer-Nield L.D., et al. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumor formation by FGN-1 (sulindac sulfone). Carcinogenesis. 19:1998;1353-1356.
    • (1998) Carcinogenesis , vol.19 , pp. 1353-1356
    • Malkinson, A.M.1    Koski, K.M.2    Dwyer-Nield, L.D.3
  • 92
    • 0033572578 scopus 로고    scopus 로고
    • Synergistic effects of new chemopreventive agents and conventional cytotoxic agents against human lung cancer cell lines
    • Soriano A.F., Helfrich B., Chan D.C., Heasley L.E., Bunn P.A., Chou T.-C. Synergistic effects of new chemopreventive agents and conventional cytotoxic agents against human lung cancer cell lines. Cancer Res. 59:1999;6178-6184.
    • (1999) Cancer Res. , vol.59 , pp. 6178-6184
    • Soriano, A.F.1    Helfrich, B.2    Chan, D.C.3    Heasley, L.E.4    Bunn, P.A.5    Chou, T.-C.6
  • 93
    • 0002500022 scopus 로고    scopus 로고
    • Non-small cell lung cancer chemotherapy
    • H.I. Pass, J.B. Mitchell, D.H. Johnson, & A. Turrisi. Philadelphia, PA: Lippincott-Raven Press
    • Bonomi P. Non-small cell lung cancer chemotherapy. Pass H.I., Mitchell J.B., Johnson D.H., Turrisi A. Lung Cancer: Principles and Practice. 1996;811-824 Lippincott-Raven Press, Philadelphia, PA.
    • (1996) Lung Cancer: Principles and Practice , pp. 811-824
    • Bonomi, P.1
  • 94
    • 0033067525 scopus 로고    scopus 로고
    • DT-diaphorase activity in NSCLC and SCLC cell lines: A role for fos/jun regulation
    • Kepa J.K., Ross D. DT-diaphorase activity in NSCLC and SCLC cell lines: a role for fos/jun regulation. Brit. J. Cancer. 79:1999;1679-1684.
    • (1999) Brit. J. Cancer , vol.79 , pp. 1679-1684
    • Kepa, J.K.1    Ross, D.2
  • 95
    • 0032435478 scopus 로고    scopus 로고
    • A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: Identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent
    • Winski S.L., Hargreaves R.H.J., Butler J., Ross D. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent. Clin. Cancer Res. 4:1998;3083-3088.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 3083-3088
    • Winski, S.L.1    Hargreaves, R.H.J.2    Butler, J.3    Ross, D.4
  • 96
    • 0027463709 scopus 로고
    • The A/J mouse lung as a model for developing new chemointervention strategies
    • Belinsky S.A., Stefanski S.A., Anderson M.W. The A/J mouse lung as a model for developing new chemointervention strategies. Cancer Res. 53:1993;410-416.
    • (1993) Cancer Res. , vol.53 , pp. 410-416
    • Belinsky, S.A.1    Stefanski, S.A.2    Anderson, M.W.3
  • 97
    • 0034652597 scopus 로고    scopus 로고
    • A germ-line p53 mutation accelerates pulmonary tumorigenesis: P53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin
    • Zhang Z., Liu Q., Lantry L.E., et al. A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin. Cancer Res. 60:2000;901-907.
    • (2000) Cancer Res. , vol.60 , pp. 901-907
    • Zhang, Z.1    Liu, Q.2    Lantry, L.E.3
  • 98
    • 0002845075 scopus 로고    scopus 로고
    • Selective pulmonary prostacylin synthase overexpression in transgenic mice is chemoprotective against lung tumorigenesis
    • Keith R.L., Miller Y.E., Malkinson A.M., Moore M.D., Geraci M.W. Selective pulmonary prostacylin synthase overexpression in transgenic mice is chemoprotective against lung tumorigenesis. Am. J. Resp. Crit. Care. Med. 159:1999;A206.
    • (1999) Am. J. Resp. Crit. Care. Med. , vol.159 , pp. 206
    • Keith, R.L.1    Miller, Y.E.2    Malkinson, A.M.3    Moore, M.D.4    Geraci, M.W.5
  • 99
    • 0025879273 scopus 로고
    • Modulation of cis-diamine-dichloroplatinum (II) accumulation and sensitivity by forskolin and 3-isobutyl-1-methlylxanthine in sensitive and resistant human ovarian carcinoma cells
    • Mann S.C., Andrews P.A., Howell S.B. Modulation of cis-diamine-dichloroplatinum (II) accumulation and sensitivity by forskolin and 3-isobutyl-1-methlylxanthine in sensitive and resistant human ovarian carcinoma cells. Int. J. Cancer. 48:1991;866.
    • (1991) Int. J. Cancer , vol.48 , pp. 866
    • Mann, S.C.1    Andrews, P.A.2    Howell, S.B.3
  • 100
    • 0025343819 scopus 로고
    • Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin
    • Lange-Carter C.A., Fossli T., Jahnsen T., Malkinson A.M. Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin. J. Biol. Chem. 265:1990;7814-7818.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7814-7818
    • Lange-Carter, C.A.1    Fossli, T.2    Jahnsen, T.3    Malkinson, A.M.4
  • 101
  • 102
    • 0031846031 scopus 로고    scopus 로고
    • Frequent reduction of gap junctional intercellular communication and connexin 43 expression in human and mouse lung carcinoma cells
    • Cesen-Cummings K., Fernstrom M.J., Malkinson A.M., Ruch R.J. Frequent reduction of gap junctional intercellular communication and connexin 43 expression in human and mouse lung carcinoma cells. Carcinogenesis. 19:1998;61-68.
    • (1998) Carcinogenesis , vol.19 , pp. 61-68
    • Cesen-Cummings, K.1    Fernstrom, M.J.2    Malkinson, A.M.3    Ruch, R.J.4
  • 103
    • 85088332288 scopus 로고    scopus 로고
    • Defective gap junctional intercellular communication in lung cancer: Loss of an important mediator of tissue homeostasis and phenotypic regulation
    • in press
    • Ruch RJ, Porter S, Koffler LD, Dwyer-nield LD, Malkinson AM. Defective gap junctional intercellular communication in lung cancer: loss of an important mediator of tissue homeostasis and phenotypic regulation. Exp Lung Res, in press.
    • Exp Lung Res
    • Ruch, R.J.1    Porter, S.2    Koffler, L.D.3    Dwyer-Nield, L.D.4    Malkinson, A.M.5
  • 104
    • 0034039086 scopus 로고    scopus 로고
    • Experimental evidence from an animal model of adenocarcinoma that chronic inflammation enhances lung cancer risk
    • Malkinson A.M., Bauer A., Meyer A., et al. Experimental evidence from an animal model of adenocarcinoma that chronic inflammation enhances lung cancer risk. Chest. 117:2000;S228.
    • (2000) Chest , vol.117 , pp. 228
    • Malkinson, A.M.1    Bauer, A.2    Meyer, A.3


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