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Volumn 8, Issue 7, 2012, Pages 1208-1215

Preclinical evaluation of a pulmonary delivered paclitaxel-loaded lipid nanocarrier antitumor effect

Author keywords

Lung metastases; Paclitaxel; Pulmonary administration; SLN PTX; Solid lipid nanoparticles

Indexed keywords

ANTICANCER DRUG; ANTITUMOR EFFECT; CANCER THERAPY; COLLOIDAL CARRIERS; COLLOIDAL SYSTEM; HIGH CONCENTRATION; LIPID NANOCARRIER; LUNG CANCER; LUNG METASTASIS; PACLITAXEL; POORLY SOLUBLE DRUGS; RESEARCH EFFORTS; SLN-PTX; SOLID LIPID NANOPARTICLE (SLN); SOLID LIPID NANOPARTICLES; SOLID TUMORS; THERAPEUTIC INDEX;

EID: 84866515787     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.12.007     Document Type: Article
Times cited : (117)

References (51)
  • 1
    • 42649137232 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles for the treatment of lung diseases
    • Azarmi S., Roa W., Lobenberg R. Targeted delivery of nanoparticles for the treatment of lung diseases. Adv Drug Deliv Rev 2008, 60:863-875.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 863-875
    • Azarmi, S.1    Roa, W.2    Lobenberg, R.3
  • 2
    • 33746319850 scopus 로고    scopus 로고
    • Emerging implications of nanotechnology on cancer diagnostics and therapeutics
    • Cuenca A.G., Jiang H., Hochwald S.N., Delano M., Cance W.G., Grobmyer S.R. Emerging implications of nanotechnology on cancer diagnostics and therapeutics. Cancer 2006, 107:459-466.
    • (2006) Cancer , vol.107 , pp. 459-466
    • Cuenca, A.G.1    Jiang, H.2    Hochwald, S.N.3    Delano, M.4    Cance, W.G.5    Grobmyer, S.R.6
  • 3
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: opportunities and challenges
    • Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005, 5:161-171.
    • (2005) Nat Rev Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 5
    • 78650641554 scopus 로고    scopus 로고
    • Nanocarriers for pulmonary administration of peptides an therapeutic proteins
    • Andrade F., Videira M., Ferreira D., Sarmento B. Nanocarriers for pulmonary administration of peptides an therapeutic proteins. Nanomedicine 2011, 6:123-141.
    • (2011) Nanomedicine , vol.6 , pp. 123-141
    • Andrade, F.1    Videira, M.2    Ferreira, D.3    Sarmento, B.4
  • 9
    • 0042129873 scopus 로고    scopus 로고
    • Paclitaxel (Taxol) and taxoid derivates for lung cancer treatment: potential for aerosol delivery
    • Gautam A., Koshkina N. Paclitaxel (Taxol) and taxoid derivates for lung cancer treatment: potential for aerosol delivery. Curr Cancer Drug Targets 2003, 3:287-296.
    • (2003) Curr Cancer Drug Targets , vol.3 , pp. 287-296
    • Gautam, A.1    Koshkina, N.2
  • 10
    • 0034787791 scopus 로고    scopus 로고
    • Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model
    • Koshkina N., Waldrep J.C., Roberts L.E., Golunski E., Melton S., Knight V. Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model. Clin Cancer Res 2001, 7:3258-3262.
    • (2001) Clin Cancer Res , vol.7 , pp. 3258-3262
    • Koshkina, N.1    Waldrep, J.C.2    Roberts, L.E.3    Golunski, E.4    Melton, S.5    Knight, V.6
  • 11
    • 2942562025 scopus 로고    scopus 로고
    • Docetaxel and paclitaxel in the treatment of breast cancer: a review of clinical experience
    • Crown J., O'Leary M., Ooi W.S. Docetaxel and paclitaxel in the treatment of breast cancer: a review of clinical experience. Oncologist 2004, 9:24-32.
    • (2004) Oncologist , vol.9 , pp. 24-32
    • Crown, J.1    O'Leary, M.2    Ooi, W.S.3
  • 12
    • 84866489436 scopus 로고    scopus 로고
    • Concurrent paclitaxel-containing regimens and thoracic radiation therapy for limited-disease small cell lung cancer
    • Ettinger D.S. Concurrent paclitaxel-containing regimens and thoracic radiation therapy for limited-disease small cell lung cancer. Semin Radiat Oncol 1999, 2:48-50.
    • (1999) Semin Radiat Oncol , vol.2 , pp. 48-50
    • Ettinger, D.S.1
  • 14
    • 0035963277 scopus 로고    scopus 로고
    • Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
    • Giannakakou P., Robey R., Fojo T., Blagosklonny M.V. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity. Oncogene 2001, 20:3806-3813.
    • (2001) Oncogene , vol.20 , pp. 3806-3813
    • Giannakakou, P.1    Robey, R.2    Fojo, T.3    Blagosklonny, M.V.4
  • 15
    • 0036184739 scopus 로고    scopus 로고
    • Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460
    • Huisman C., Ferreira C.G., Broker L.E., Rodriguez J.A., Smit E.F., Postmus P.E., et al. Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. Clin Cancer Res 2002, 8:596-606.
    • (2002) Clin Cancer Res , vol.8 , pp. 596-606
    • Huisman, C.1    Ferreira, C.G.2    Broker, L.E.3    Rodriguez, J.A.4    Smit, E.F.5    Postmus, P.E.6
  • 16
    • 14944349359 scopus 로고    scopus 로고
    • Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim
    • Li R., Moudgil T., Ross H.J., Hu H.M. Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. Cell Death Differ 2005, 12:292-303.
    • (2005) Cell Death Differ , vol.12 , pp. 292-303
    • Li, R.1    Moudgil, T.2    Ross, H.J.3    Hu, H.M.4
  • 17
    • 0242468010 scopus 로고    scopus 로고
    • Taxol inhibits melanoma metastases through apoptosis induction, angiogenesis inhibition, and restoration of e-cadherin and nm23 expression
    • Wang F., Cai Y., Zhao W., Liu H., Fu Z., Han R. Taxol inhibits melanoma metastases through apoptosis induction, angiogenesis inhibition, and restoration of e-cadherin and nm23 expression. J Pharmacol Sci 2003, 93:197-203.
    • (2003) J Pharmacol Sci , vol.93 , pp. 197-203
    • Wang, F.1    Cai, Y.2    Zhao, W.3    Liu, H.4    Fu, Z.5    Han, R.6
  • 18
    • 0031920710 scopus 로고    scopus 로고
    • Induction of apoptosis by Taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cancer cells
    • Zaffaroni N., Silvestrini R., Orlandi L., Bearzatto A., Gornati D., Villa R. Induction of apoptosis by Taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cancer cells. Br J Cancer 1998, 77:1378-1385.
    • (1998) Br J Cancer , vol.77 , pp. 1378-1385
    • Zaffaroni, N.1    Silvestrini, R.2    Orlandi, L.3    Bearzatto, A.4    Gornati, D.5    Villa, R.6
  • 19
    • 84967647320 scopus 로고    scopus 로고
    • Solid Lipid nanoparticles as drug carriers
    • Imperial College Press, Northeastern University, MA, V. Torchilin (Ed.)
    • Mader K. Solid Lipid nanoparticles as drug carriers. Nanoparticulates as drug carriers 2006, 187-212. Imperial College Press, Northeastern University, MA. V. Torchilin (Ed.).
    • (2006) Nanoparticulates as drug carriers , pp. 187-212
    • Mader, K.1
  • 20
    • 33846677328 scopus 로고    scopus 로고
    • Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles
    • Lee M.K., Lim S.J., Kim C.K. Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles. Biomaterials 2007, 28:2137-2146.
    • (2007) Biomaterials , vol.28 , pp. 2137-2146
    • Lee, M.K.1    Lim, S.J.2    Kim, C.K.3
  • 21
    • 77957595695 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: a novel carrier for chemotherapy
    • Shaji J., Jain V. Solid lipid nanoparticles: a novel carrier for chemotherapy. Int J Pharm Pharm Sci 2010, 2:8-17.
    • (2010) Int J Pharm Pharm Sci , vol.2 , pp. 8-17
    • Shaji, J.1    Jain, V.2
  • 24
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immun Methods 1983, 65:55-63.
    • (1983) J Immun Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 25
    • 0030612803 scopus 로고    scopus 로고
    • Metastatic ability of MXT mouse mammary subpopulations correlates with clonal expression and/or membrane-association of gelatinase A
    • Llorens A., Vinyals A., Alía P., López-Barcons L., Gonzalez-Garrigues M., Fabra A. Metastatic ability of MXT mouse mammary subpopulations correlates with clonal expression and/or membrane-association of gelatinase A. Molecular Carcinogenesis 1997, 19:54-66.
    • (1997) Molecular Carcinogenesis , vol.19 , pp. 54-66
    • Llorens, A.1    Vinyals, A.2    Alía, P.3    López-Barcons, L.4    Gonzalez-Garrigues, M.5    Fabra, A.6
  • 26
    • 0344420217 scopus 로고    scopus 로고
    • Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems
    • Jones A.T., Gumbleton M., Duncan R. Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems. Adv Drug Del Rev 2003, 55:1353-1357.
    • (2003) Adv Drug Del Rev , vol.55 , pp. 1353-1357
    • Jones, A.T.1    Gumbleton, M.2    Duncan, R.3
  • 28
    • 34548209237 scopus 로고    scopus 로고
    • Biodegradable Nanoparticles for cytosolic delivery of therapeutics
    • Vasir J.K., Labhasetwar V. Biodegradable Nanoparticles for cytosolic delivery of therapeutics. Adv Drug Del Rev 2007, 59:718-728.
    • (2007) Adv Drug Del Rev , vol.59 , pp. 718-728
    • Vasir, J.K.1    Labhasetwar, V.2
  • 29
    • 0034212385 scopus 로고    scopus 로고
    • Paclitaxel-induced cell death: where the cell cycle and apoptosis come together
    • Wang T.H., Wang H.S., Soong Y.K. Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 2000, 88.
    • (2000) Cancer , vol.88
    • Wang, T.H.1    Wang, H.S.2    Soong, Y.K.3
  • 30
    • 33746449598 scopus 로고    scopus 로고
    • Susceptibility of nanoparticle-encapsulated paclitaxel to P-glycoprotein-mediated drug efflux
    • Chavanpatil M.D., Patil Y., Panyam J. Susceptibility of nanoparticle-encapsulated paclitaxel to P-glycoprotein-mediated drug efflux. Int J of Pharm 2006, 320:150-156.
    • (2006) Int J of Pharm , vol.320 , pp. 150-156
    • Chavanpatil, M.D.1    Patil, Y.2    Panyam, J.3
  • 31
    • 0034605981 scopus 로고    scopus 로고
    • Cellular uptake and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or paclitaxel
    • Miglietta A., Cavalli R., Bocca C., Gabriel L., Gasco M.R. Cellular uptake and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or paclitaxel. Int J Pharm 2000, 210:61-67.
    • (2000) Int J Pharm , vol.210 , pp. 61-67
    • Miglietta, A.1    Cavalli, R.2    Bocca, C.3    Gabriel, L.4    Gasco, M.R.5
  • 32
    • 4644268591 scopus 로고    scopus 로고
    • Cytotoxicity of anticancer drugs incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line
    • Serpe L., Catalano M.G., Cavalli R., Ugazio E., Bosco O., Canaparo R., et al. Cytotoxicity of anticancer drugs incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line. Eur J Pharm Biopharm 2004, 58:673-680.
    • (2004) Eur J Pharm Biopharm , vol.58 , pp. 673-680
    • Serpe, L.1    Catalano, M.G.2    Cavalli, R.3    Ugazio, E.4    Bosco, O.5    Canaparo, R.6
  • 33
    • 0029913172 scopus 로고    scopus 로고
    • Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway
    • Blagosklonny M.V., Schulte T., Nguyen P., Trepel J., Neckers L.M. Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res 1996, 56:1851-1854.
    • (1996) Cancer Res , vol.56 , pp. 1851-1854
    • Blagosklonny, M.V.1    Schulte, T.2    Nguyen, P.3    Trepel, J.4    Neckers, L.M.5
  • 34
    • 0028061972 scopus 로고
    • Relationship between the structure of Taxol and other taxanes on induction of tumor necrosis factor-a gene expression and cytotoxicity
    • Burkhart C.A., Berman J.W., Swindell C., Horwitz S.B. Relationship between the structure of Taxol and other taxanes on induction of tumor necrosis factor-a gene expression and cytotoxicity. Cancer Res 1994, 54:5779-5782.
    • (1994) Cancer Res , vol.54 , pp. 5779-5782
    • Burkhart, C.A.1    Berman, J.W.2    Swindell, C.3    Horwitz, S.B.4
  • 35
    • 75549087162 scopus 로고    scopus 로고
    • Nanosystem drug targeting: Facing up to complex realities
    • Ruenraroengsak P., Cook J.M., Florence A.T. Nanosystem drug targeting: Facing up to complex realities. J Control Release 2010, 141:265-276.
    • (2010) J Control Release , vol.141 , pp. 265-276
    • Ruenraroengsak, P.1    Cook, J.M.2    Florence, A.T.3
  • 36
    • 33745605771 scopus 로고    scopus 로고
    • Nanotechnology: intelligent design to treat complex disease
    • Couvreur P., Vauthier C. Nanotechnology: intelligent design to treat complex disease. Pharm Res 2006, 23:1417-1450.
    • (2006) Pharm Res , vol.23 , pp. 1417-1450
    • Couvreur, P.1    Vauthier, C.2
  • 37
    • 34250165021 scopus 로고    scopus 로고
    • Nanotechnology platforms and physiological challenges for cancer therapeutics
    • Kim K.Y. Nanotechnology platforms and physiological challenges for cancer therapeutics. Nanomedicine 2007, 3:103-110.
    • (2007) Nanomedicine , vol.3 , pp. 103-110
    • Kim, K.Y.1
  • 38
    • 4444379133 scopus 로고    scopus 로고
    • Nanoparticle and targeted systems for cancer therapy
    • Brannon-Peppas L., Blanchette J.O. Nanoparticle and targeted systems for cancer therapy. Adv Drug Del Rev 2004, 56:1649-1659.
    • (2004) Adv Drug Del Rev , vol.56 , pp. 1649-1659
    • Brannon-Peppas, L.1    Blanchette, J.O.2
  • 39
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
    • Maeda H., Wua J., Sawaa T., Matsumurab Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000, 65:271-284.
    • (2000) J Control Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wua, J.2    Sawaa, T.3    Matsumurab, Y.4    Hori, K.5
  • 40
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability and retention effect for tumor targeting
    • Iyer A.K., Khaled G., Fang J., Maeda H. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discov Today 2006, 11:812-818.
    • (2006) Drug Discov Today , vol.11 , pp. 812-818
    • Iyer, A.K.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 41
    • 33745070553 scopus 로고    scopus 로고
    • Structure function relationships in the lymphatic system and implications for cancer biology
    • Witte M.H., Jones K., Wilting J., Dictor M., Selg M., McHale N., et al. Structure function relationships in the lymphatic system and implications for cancer biology. Cancer Metastasis Rev 2006, 25:159-184.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 159-184
    • Witte, M.H.1    Jones, K.2    Wilting, J.3    Dictor, M.4    Selg, M.5    McHale, N.6
  • 42
    • 0037508920 scopus 로고    scopus 로고
    • Factors and mechanism of "EPR" effect and the enhanced antitumor effects of macromolecular drugs including SMANCS
    • Fang F., Sawa T., Maeda H. Factors and mechanism of "EPR" effect and the enhanced antitumor effects of macromolecular drugs including SMANCS. Adv Exp Med Biol 2003, 519:29-49.
    • (2003) Adv Exp Med Biol , vol.519 , pp. 29-49
    • Fang, F.1    Sawa, T.2    Maeda, H.3
  • 44
    • 3042858653 scopus 로고    scopus 로고
    • Tumor efficacy and biodistribution of linear polyethylenimine-cholesterol/DNA complexes
    • Furgeson D.Y., Yockman J.W., Janat M.M., Kim S.W. Tumor efficacy and biodistribution of linear polyethylenimine-cholesterol/DNA complexes. Mol Ther 2004, 9:837-845.
    • (2004) Mol Ther , vol.9 , pp. 837-845
    • Furgeson, D.Y.1    Yockman, J.W.2    Janat, M.M.3    Kim, S.W.4
  • 45
    • 21744460519 scopus 로고    scopus 로고
    • Influence of administration route on tumor uptake and biodistribution of etoposide loaded solid lipid nanoparticles in Dalton's lymphoma tumor bearing mice
    • Harivardhan R.L., Sharma R.K., Chuttani K., Mishra A.K., Murthy R.S.R. Influence of administration route on tumor uptake and biodistribution of etoposide loaded solid lipid nanoparticles in Dalton's lymphoma tumor bearing mice. J Control Release 2005, 105:185-198.
    • (2005) J Control Release , vol.105 , pp. 185-198
    • Harivardhan, R.L.1    Sharma, R.K.2    Chuttani, K.3    Mishra, A.K.4    Murthy, R.S.R.5
  • 46
    • 11144293514 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery
    • Xu Z., Gu W., Huang J., Sui H., Zhou Z., Yang Y., et al. In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery. Int J Pharm 2005, 288:361-368.
    • (2005) Int J Pharm , vol.288 , pp. 361-368
    • Xu, Z.1    Gu, W.2    Huang, J.3    Sui, H.4    Zhou, Z.5    Yang, Y.6
  • 47
    • 41449089560 scopus 로고    scopus 로고
    • Cyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in mice
    • Koshkina N.V., Golunski E., Roberts E., Gilbert B., Knight V. Cyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in mice. J Aerosol Med 2004, 115:395-404.
    • (2004) J Aerosol Med , vol.115 , pp. 395-404
    • Koshkina, N.V.1    Golunski, E.2    Roberts, E.3    Gilbert, B.4    Knight, V.5
  • 48
    • 0347418154 scopus 로고    scopus 로고
    • Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages
    • Vyas S.P., Kannan M.E., Jain S., Mishra V., Singh P. Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages. Int J Pharm 2004, 269:37-49.
    • (2004) Int J Pharm , vol.269 , pp. 37-49
    • Vyas, S.P.1    Kannan, M.E.2    Jain, S.3    Mishra, V.4    Singh, P.5
  • 49
    • 33748126226 scopus 로고    scopus 로고
    • Recent approaches to intracellular delivery of drugs and dna and organelle targeting
    • Torchilin V.P. Recent approaches to intracellular delivery of drugs and dna and organelle targeting. Annu Rev Biomed Eng 2006, 8:343-375.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 343-375
    • Torchilin, V.P.1
  • 51
    • 33646384586 scopus 로고    scopus 로고
    • Parameters influencing the stealthiness of colloidal drug delivery systems
    • Vonarbourg A., Passirani C., Saulnier P., Benoit J.P. Parameters influencing the stealthiness of colloidal drug delivery systems. Biomaterials 2006, 27:4356-4373.
    • (2006) Biomaterials , vol.27 , pp. 4356-4373
    • Vonarbourg, A.1    Passirani, C.2    Saulnier, P.3    Benoit, J.P.4


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