Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

Biomaterials

Volumn 33, Issue 5, 2012, Pages 1477-1488

  Khan, Mohd Imran ^a   Mohammad, Akbar ^b   Patil, Govil ^a   Naqvi, S A H ^b   Chauhan, L K S ^a   Ahmad, Iqbal ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

Autophagy; Iron oxide NPs; Mitochondrial damage; Necrosis; ROS

Indexed keywords

A549 CELLS; AUTOPHAGY; CANCER CELLS; CANCEROUS CELLS; CELLULAR VIABILITY; CYTOTOXIC; EPITHELIAL CANCER CELLS; HUMAN CANCER CELLS; HUMAN LUNG FIBROBLASTS; IRON OXIDE NANOPARTICLE; MITOCHONDRIAL DAMAGE; NECROSIS; PRE-TREATMENT; ROS; TUMOR THERAPY;

BIOLOGICAL ORGANS; CELL CULTURE; CELL DEATH; DISEASES; IRON; IRON RESEARCH; MITOCHONDRIA; NANOPARTICLES; TUMORS;

IRON OXIDES;

ACETYLCYSTEINE; ADENYLATE KINASE; IRON OXIDE; MAMMALIAN TARGET OF RAPAMYCIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; X RAY DIFFRACTION;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; EPITHELIAL CELLS; FERRIC COMPOUNDS; FLUORESCENCE; HUMANS; INTRACELLULAR SPACE; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ATOMIC FORCE; MITOCHONDRIA; NANOPARTICLES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TOR SERINE-THREONINE KINASES; X-RAY DIFFRACTION;

EID: 83355166280     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.10.080     Document Type: Article

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