Intranasal immunization with poly(γ-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity

Journal of Controlled Release

Volumn 152, Issue 2, 2011, Pages 310-316

  Matsuo, Keisuke ^a,b   Koizumi, Hayato ^c   Akashi, Mitsuru ^a,b   Nakagawa, Shinsaku ^a,b   Fujita, Takuya ^c,d   Yamamoto, Akira ^c   Okada, Naoki ^a,b,c  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^d RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

PGA nanoparticle; Antigen delivery carrier; Intranasal vaccination; Tumor immunity

Indexed keywords

AMPHIPHILICS; ANTI-TUMOR ACTIVITIES; ANTI-TUMOR EFFICACY; ANTIGEN DELIVERY; ANTIGEN-DELIVERY CARRIER; CANCER VACCINE; CERVICAL LYMPH NODES; CYTOTOXIC T LYMPHOCYTES; GLUTAMIC ACID; IMMUNE RESPONSE; INTRANASAL; LUNG METASTASIS; LYMPH NODE; LYMPHOID TISSUE; NASAL CAVITY; NASAL VACCINATION; NON-INVASIVE; OVALBUMINS; TUMOR CELLS;

AMINO ACIDS; BODY FLUIDS; IMMUNIZATION; MAMMALS; NANOPARTICLES; RESPIRATORY MECHANICS; TUMORS; VACCINES;

ANTIGENS;

NANOPARTICLE; OVALBUMIN; POLY(GAMMA GLUTAMIC ACID); POLYGLUTAMIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNIZATION; CERVICAL LYMPH NODE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; MOUSE; NONHUMAN; NOSE CAVITY; PRIORITY JOURNAL; TUMOR IMMUNITY;

ADMINISTRATION, INTRANASAL; ANIMALS; CANCER VACCINES; CELL LINE, TUMOR; DRUG CARRIERS; FEMALE; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; NANOPARTICLES; NEOPLASMS; OVALBUMIN; POLYGLUTAMIC ACID;

EID: 79958245618     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.009     Document Type: Article

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