-
1
-
-
78651314500
-
Potential clinical applications of siRNA technique: Benefts and limitations
-
Chen, SH and Zhaori, G (2011). Potential clinical applications of siRNA technique: benefts and limitations. Eur J Clin Invest 41: 221-232.
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 221-232
-
-
Chen, S.H.1
Zhaori, G.2
-
2
-
-
80052627990
-
Current progress of siRNA/shRNA therapeutics in clinical trials
-
Burnett, JC, Rossi, JJ and Tiemann, K (2011). Current progress of siRNA/shRNA therapeutics in clinical trials. Biotechnol J 6: 1130-1146.
-
(2011)
Biotechnol J
, vol.6
, pp. 1130-1146
-
-
Burnett, J.C.1
Rossi, J.J.2
Tiemann, K.3
-
3
-
-
67649295505
-
SiRNA delivery systems for cancer treatment
-
Oh, YK and Park, TG (2009). siRNA delivery systems for cancer treatment. Adv Drug Deliv Rev 61: 850-862.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 850-862
-
-
Oh, Y.K.1
Park, T.G.2
-
4
-
-
78649659237
-
Delivery of siRNA therapeutics: Barriers and carriers
-
Wang, J, Lu, Z, Wientjes, MG and Au, JL (2010). Delivery of siRNA therapeutics: barriers and carriers. AAPS J 12: 492-503.
-
(2010)
AAPS J
, vol.12
, pp. 492-503
-
-
Wang, J.1
Lu, Z.2
Wientjes, M.G.3
Au, J.L.4
-
5
-
-
78449309070
-
Effcient and targeted delivery of siRNA in vivo
-
Shim, MS and Kwon, YJ (2010). Effcient and targeted delivery of siRNA in vivo. FEBS J 277: 4814-4827.
-
(2010)
FEBS J
, vol.277
, pp. 4814-4827
-
-
Shim, M.S.1
Kwon, Y.J.2
-
6
-
-
51049084639
-
Inhalable siRNA: Potential as a therapeutic agent in the lungs
-
Durcan, N, Murphy, C and Cryan, SA (2008). Inhalable siRNA: potential as a therapeutic agent in the lungs. Mol Pharm 5: 559-566.
-
(2008)
Mol Pharm
, vol.5
, pp. 559-566
-
-
Durcan, N.1
Murphy, C.2
Cryan, S.A.3
-
7
-
-
84856956282
-
Delivery of siRNA to the mouse lung via a functionalized lipopolyamine
-
Polach, KJ, Matar, M, Rice, J, Slobodkin, G, Sparks, J, Congo, R et al. (2012). Delivery of siRNA to the mouse lung via a functionalized lipopolyamine. Mol Ther 20: 91-100.
-
(2012)
Mol Ther
, vol.20
, pp. 91-100
-
-
Polach, K.J.1
Matar, M.2
Rice, J.3
Slobodkin, G.4
Sparks, J.5
Congo, R.6
-
8
-
-
84863928267
-
Nonviral pulmonary delivery of siRNA
-
Merkel, OM and Kissel, T (2012). Nonviral pulmonary delivery of siRNA. Acc Chem Res 45: 961-970.
-
(2012)
Acc Chem Res
, vol.45
, pp. 961-970
-
-
Merkel, O.M.1
Kissel, T.2
-
10
-
-
82955233645
-
Uptake, effcacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense
-
Moschos, SA, Frick, M, Taylor, B, Turnpenny, P, Graves, H, Spink, KG et al. (2011). Uptake, effcacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense. Mol Ther 19: 2163-2168.
-
(2011)
Mol Ther
, vol.19
, pp. 2163-2168
-
-
Moschos, S.A.1
Frick, M.2
Taylor, B.3
Turnpenny, P.4
Graves, H.5
Spink, K.G.6
-
11
-
-
46349111796
-
Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis
-
Xu, CX, Jere, D, Jin, H, Chang, SH, Chung, YS, Shin, JY et al. (2008). Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis. Am J Respir Crit Care Med 178: 60-73.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 60-73
-
-
Xu, C.X.1
Jere, D.2
Jin, H.3
Chang, S.H.4
Chung, Y.S.5
Shin, J.Y.6
-
12
-
-
79955468361
-
Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice
-
Beyerle, A, Braun, A, Merkel, O, Koch, F, Kissel, T and Stoeger, T (2011). Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice. J Control Release 151: 51-56.
-
(2011)
J Control Release
, vol.151
, pp. 51-56
-
-
Beyerle, A.1
Braun, A.2
Merkel, O.3
Koch, F.4
Kissel, T.5
Stoeger, T.6
-
13
-
-
84855837134
-
Design of an inhalable dry powder formulation of DOTAP-modifed PLGA nanoparticles loaded with siRNA
-
Jensen, DK, Jensen, LB, Koocheki, S, Bengtson, L, Cun, D, Nielsen, HM et al. (2012). Design of an inhalable dry powder formulation of DOTAP-modifed PLGA nanoparticles loaded with siRNA. J Control Release 157: 141-148.
-
(2012)
J Control Release
, vol.157
, pp. 141-148
-
-
Jensen, D.K.1
Jensen, L.B.2
Koocheki, S.3
Bengtson, L.4
Cun, D.5
Nielsen, H.M.6
-
14
-
-
66249123291
-
Hyaluronic acid-modifed DOTAP/DOPE liposomes for the targeted delivery of anti-telomerase siRNA to CD44-expressing lung cancer cells
-
Taetz, S, Bochot, A, Surace, C, Arpicco, S, Renoir, JM, Schaefer, UF et al. (2009). Hyaluronic acid-modifed DOTAP/DOPE liposomes for the targeted delivery of anti-telomerase siRNA to CD44-expressing lung cancer cells. Oligonucleotides 19: 103-116.
-
(2009)
Oligonucleotides
, vol.19
, pp. 103-116
-
-
Taetz, S.1
Bochot, A.2
Surace, C.3
Arpicco, S.4
Renoir, J.M.5
Schaefer, U.F.6
-
15
-
-
79959915264
-
Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery
-
Tagalakis, AD, He, L, Saraiva, L, Gustafsson, KT and Hart, SL (2011). Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery. Biomaterials 32: 6302-6315.
-
(2011)
Biomaterials
, vol.32
, pp. 6302-6315
-
-
Tagalakis, A.D.1
He, L.2
Saraiva, L.3
Gustafsson, K.T.4
Hart, S.L.5
-
16
-
-
0032799734
-
Characterization of vascular gene transfer using a novel cationic lipid
-
Matsumura, JS, Kim, R, Shively, VP, MacDonald, RC and Pearce, WH (1999). Characterization of vascular gene transfer using a novel cationic lipid. J Surg Res 85: 339-345.
-
(1999)
J Surg Res
, vol.85
, pp. 339-345
-
-
Matsumura, J.S.1
Kim, R.2
Shively, V.P.3
MacDonald, R.C.4
Pearce, W.H.5
-
17
-
-
0032552426
-
Biodistribution and gene expression of lipid/plasmid complexes after systemic administration
-
Mahato, RI, Anwer, K, Tagliaferri, F, Meaney, C, Leonard, P, Wadhwa, MS et al. (1998). Biodistribution and gene expression of lipid/plasmid complexes after systemic administration. Hum Gene Ther 9: 2083-2099.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2083-2099
-
-
Mahato, R.I.1
Anwer, K.2
Tagliaferri, F.3
Meaney, C.4
Leonard, P.5
Wadhwa, M.S.6
-
18
-
-
80155150303
-
Personalized medicine in lung cancer: What we need to know
-
Mok, TS (2011). Personalized medicine in lung cancer: what we need to know. Nat Rev Clin Oncol 8: 661-668.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 661-668
-
-
Mok, T.S.1
-
19
-
-
33845612190
-
Analysis and optimization of the cationic lipid component of a lipid/peptide vector formulation for enhanced transfection in vitro and in vivo
-
Writer, M, Hurley, CA, Sarkar, S, Copeman, DM, Wong, JB, Odlyha, M et al. (2006). Analysis and optimization of the cationic lipid component of a lipid/peptide vector formulation for enhanced transfection in vitro and in vivo. J Liposome Res 16: 373-389.
-
(2006)
J Liposome Res
, vol.16
, pp. 373-389
-
-
Writer, M.1
Hurley, C.A.2
Sarkar, S.3
Copeman, D.M.4
Wong, J.B.5
Odlyha, M.6
-
20
-
-
77951498926
-
DC-Chol/DOPE cationic liposomes: A comparative study of the infuence factors on plasmid pDNA and siRNA gene delivery
-
Zhang, Y, Li, H, Sun, J, Gao, J, Liu, W, Li, B et al. (2010). DC-Chol/DOPE cationic liposomes: a comparative study of the infuence factors on plasmid pDNA and siRNA gene delivery. Int J Pharm 390: 198-207.
-
(2010)
Int J Pharm
, vol.390
, pp. 198-207
-
-
Zhang, Y.1
Li, H.2
Sun, J.3
Gao, J.4
Liu, W.5
Li, B.6
-
21
-
-
0032820002
-
O-ethylphosphatidylcholine: A metabolizable cationic phospholipid which is a serum-compatible DNA transfection agent
-
MacDonald, RC, Rakhmanova, VA, Choi, KL, Rosenzweig, HS and Lahiri, MK (1999). O-ethylphosphatidylcholine: A metabolizable cationic phospholipid which is a serum-compatible DNA transfection agent. J Pharm Sci 88: 896-904.
-
(1999)
J Pharm Sci
, vol.88
, pp. 896-904
-
-
MacDonald, R.C.1
Rakhmanova, V.A.2
Choi, K.L.3
Rosenzweig, H.S.4
Lahiri, M.K.5
-
22
-
-
34548185242
-
Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells
-
Wang, L and MacDonald, RC (2007). Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm 4: 615-623.
-
(2007)
Mol Pharm
, vol.4
, pp. 615-623
-
-
Wang, L.1
MacDonald, R.C.2
-
23
-
-
78549278716
-
Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery
-
Noh, SM, Han, SE, Shim, G, Lee, KE, Kim, CW, Han, SS et al. (2011). Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery. Biomaterials 32: 849-857.
-
(2011)
Biomaterials
, vol.32
, pp. 849-857
-
-
Noh, S.M.1
Han, S.E.2
Shim, G.3
Lee, K.E.4
Kim, C.W.5
Han, S.S.6
-
24
-
-
34547161854
-
In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments
-
Bae, Y, Nishiyama, N and Kataoka, K (2007). In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments. Bioconjug Chem 18: 1131-1139.
-
(2007)
Bioconjug Chem
, vol.18
, pp. 1131-1139
-
-
Bae, Y.1
Nishiyama, N.2
Kataoka, K.3
-
25
-
-
19444372923
-
A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
-
Moghimi, SM, Symonds, P, Murray, JC, Hunter, AC, Debska, G and Szewczyk, A (2005). A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 11: 990-995.
-
(2005)
Mol Ther
, vol.11
, pp. 990-995
-
-
Moghimi, S.M.1
Symonds, P.2
Murray, J.C.3
Hunter, A.C.4
Debska, G.5
Szewczyk, A.6
-
26
-
-
77953809654
-
Cationic carriers of genetic material and cell death: A mitochondrial tale
-
Hunter, AC and Moghimi, SM (2010). Cationic carriers of genetic material and cell death: a mitochondrial tale. Biochim Biophys Acta 1797: 1203-1209.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 1203-1209
-
-
Hunter, A.C.1
Moghimi, S.M.2
-
27
-
-
81355138363
-
Cationic phospholiposomes: Effcient delivery vehicles of anticancer derivatives of ATP to multiple myeloma cells
-
Wang, L and MacDonald, RC (2011). Cationic phospholiposomes: effcient delivery vehicles of anticancer derivatives of ATP to multiple myeloma cells. J Liposome Res 21: 306-314.
-
(2011)
J Liposome Res
, vol.21
, pp. 306-314
-
-
Wang, L.1
MacDonald, R.C.2
-
28
-
-
25144453314
-
Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells
-
Song, L, Coppola, D, Livingston, S, Cress, D and Haura, EB (2005). Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells. Cancer Biol Ther 4: 267-276.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 267-276
-
-
Song, L.1
Coppola, D.2
Livingston, S.3
Cress, D.4
Haura, E.B.5
-
29
-
-
70949089720
-
Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells
-
Simonin, K, Brotin, E, Dufort, S, Dutoit, S, Goux, D, N'diaye, M et al. (2009). Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells. Mol Cancer Ther 8: 3162-3170.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3162-3170
-
-
Simonin, K.1
Brotin, E.2
Dufort, S.3
Dutoit, S.4
Goux N'Diaye D, M.5
-
30
-
-
84872675104
-
MiR-101 and Mcl-1 in non-small-cell lung cancer: Expression profle and clinical signifcance
-
Luo, L, Zhang, T, Liu, H, Lv, T, Yuan, D, Yao, Y et al. (2012). MiR-101 and Mcl-1 in non-small-cell lung cancer: expression profle and clinical signifcance. Med Oncol 29: 1681-1686.
-
(2012)
Med Oncol
, vol.29
, pp. 1681-1686
-
-
Luo, L.1
Zhang, T.2
Liu, H.3
Lv, T.4
Yuan, D.5
Yao, Y.6
-
31
-
-
81055149759
-
Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors
-
Zhou, W, Hu, J, Tang, H, Wang, D, Huang, X, He, C et al. (2011). Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. BMC Cancer 11: 485.
-
(2011)
BMC Cancer
, vol.11
, pp. 485
-
-
Zhou, W.1
Hu, J.2
Tang, H.3
Wang, D.4
Huang, X.5
He, C.6
-
32
-
-
80052145802
-
Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug
-
Shim, G, Han, SE, Yu, YH, Lee, S, Lee, HY, Kim, K et al. (2011). Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. J Control Release 155: 60-66.
-
(2011)
J Control Release
, vol.155
, pp. 60-66
-
-
Shim, G.1
Han, S.E.2
Yu, Y.H.3
Lee, S.4
Lee, H.Y.5
Kim, K.6
-
33
-
-
84861681753
-
RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment
-
Yonenaga, N, Kenjo, E, Asai, T, Tsuruta, A, Shimizu, K, Dewa, T et al. (2012). RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment. J Control Release 160: 177-181.
-
(2012)
J Control Release
, vol.160
, pp. 177-181
-
-
Yonenaga, N.1
Kenjo, E.2
Asai, T.3
Tsuruta, A.4
Shimizu, K.5
Dewa, T.6
-
34
-
-
79959266354
-
M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis
-
Zhou, H, Roy, S, Cochran, E, Zouaoui, R, Chu, CL, Duffner, J et al. (2011). M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis. PLoS ONE 6: e21106.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhou, H.1
Roy, S.2
Cochran, E.3
Zouaoui, R.4
Chu, C.L.5
Duffner, J.6
-
35
-
-
63849114023
-
The utility of a nebulised intra-tracheal rat model of invasive pulmonary aspergillosis
-
Chandenier, J, Bernard, S, Montharu, J, Bailly, E, Fetissof, F, de Monte, M et al. (2009). The utility of a nebulised intra-tracheal rat model of invasive pulmonary aspergillosis. Mycoses 52: 239-245.
-
(2009)
Mycoses
, vol.52
, pp. 239-245
-
-
Chandenier, J.1
Bernard, S.2
Montharu, J.3
Bailly, E.4
Fetissof, F.5
De Monte, M.6
-
36
-
-
24744466699
-
Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque
-
Li, BJ, Tang, Q, Cheng, D, Qin, C, Xie, FY, Wei, Q et al. (2005). Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med 11: 944-951.
-
(2005)
Nat Med
, vol.11
, pp. 944-951
-
-
Li, B.J.1
Tang, Q.2
Cheng, D.3
Qin, C.4
Xie, F.Y.5
Wei, Q.6
-
37
-
-
0032729619
-
Physical and biological properties of cationic triesters of phosphatidylcholine
-
MacDonald, RC, Ashley, GW, Shida, MM, Rakhmanova, VA, Tarahovsky, YS, Pantazatos, DP et al. (1999). Physical and biological properties of cationic triesters of phosphatidylcholine. Biophys J 77: 2612-2629.
-
(1999)
Biophys J
, vol.77
, pp. 2612-2629
-
-
MacDonald, R.C.1
Ashley, G.W.2
Shida, M.M.3
Rakhmanova, V.A.4
Tarahovsky, Y.S.5
Pantazatos, D.P.6
-
38
-
-
76349111051
-
Rational design of cationic lipids for siRNA delivery
-
Semple, SC, Akinc, A, Chen, J, Sandhu, AP, Mui, BL, Cho, CK et al. (2010). Rational design of cationic lipids for siRNA delivery. Nat Biotechnol 28: 172-176.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 172-176
-
-
Semple, S.C.1
Akinc, A.2
Chen, J.3
Sandhu, A.P.4
Mui, B.L.5
Cho, C.K.6
-
39
-
-
43049176170
-
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
-
Akinc, A, Zumbuehl, A, Goldberg, M, Leshchiner, ES, Busini, V, Hossain, N et al. (2008). A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol 26: 561-569.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 561-569
-
-
Akinc, A.1
Zumbuehl, A.2
Goldberg, M.3
Leshchiner, E.S.4
Busini, V.5
Hossain, N.6
-
40
-
-
24944577514
-
Cationic lipid saturation infuences intracellular delivery of encapsulated nucleic acids
-
Heyes, J, Palmer, L, Bremner, K and MacLachlan, I (2005). Cationic lipid saturation infuences intracellular delivery of encapsulated nucleic acids. J Control Release 107: 276-287.
-
(2005)
J Control Release
, vol.107
, pp. 276-287
-
-
Heyes, J.1
Palmer, L.2
Bremner, K.3
MacLachlan, I.4
-
41
-
-
80052552280
-
Effcient topical delivery of plasmid DNA to lung in vivo mediated by putative triggered, PEGylated pDNA nanoparticles
-
Aissaoui, A, Chami, M, Hussein, M and Miller, AD (2011). Effcient topical delivery of plasmid DNA to lung in vivo mediated by putative triggered, PEGylated pDNA nanoparticles. J Control Release 154: 275-284.
-
(2011)
J Control Release
, vol.154
, pp. 275-284
-
-
Aissaoui, A.1
Chami, M.2
Hussein, M.3
Miller, A.D.4
-
42
-
-
84870232413
-
The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine
-
Mochizuki, S, Kanegae, N, Nishina, K, Kamikawa, Y, Koiwai, K, Masunaga, H et al. (2013). The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine. Biochim Biophys Acta 1828: 412-418.
-
(2013)
Biochim Biophys Acta
, vol.1828
, pp. 412-418
-
-
Mochizuki, S.1
Kanegae, N.2
Nishina, K.3
Kamikawa, Y.4
Koiwai, K.5
Masunaga, H.6
-
43
-
-
17644419268
-
Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection effciency
-
Zuhorn, IS, Bakowsky, U, Polushkin, E, Visser, WH, Stuart, MC, Engberts, JB et al. (2005). Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection effciency. Mol Ther 11: 801-810.
-
(2005)
Mol Ther
, vol.11
, pp. 801-810
-
-
Zuhorn, I.S.1
Bakowsky, U.2
Polushkin, E.3
Visser, W.H.4
Stuart, M.C.5
Engberts, J.B.6
-
44
-
-
84862163934
-
Lipid nanoparticles for hepatic delivery of small interfering RNA
-
Yu, B, Hsu, SH, Zhou, C, Wang, X, Terp, MC, Wu, Y et al. (2012). Lipid nanoparticles for hepatic delivery of small interfering RNA. Biomaterials 33: 5924-5934.
-
(2012)
Biomaterials
, vol.33
, pp. 5924-5934
-
-
Yu, B.1
Hsu, S.H.2
Zhou, C.3
Wang, X.4
Terp, M.C.5
Wu, Y.6
-
45
-
-
80054060205
-
Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA
-
Chang, RS, Suh, MS, Kim, S, Shim, G, Lee, S, Han, SS et al. (2011). Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA. Biomaterials 32: 9785-9795.
-
(2011)
Biomaterials
, vol.32
, pp. 9785-9795
-
-
Chang, R.S.1
Suh, M.S.2
Kim, S.3
Shim, G.4
Lee, S.5
Han, S.S.6
|