Impact of hexavalent chromium on mammalian cell bioenergetics: Phenotypic changes, molecular basis and potential relevance to chromate-induced lung cancer

BioMetals

Volumn 27, Issue 3, 2014, Pages 409-443

  Abreu, P L ^a   Ferreira, L M R ^b   Alpoim, M C ^a,c,d   Urbano, A M ^a,c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Chromate induced lung cancer; Energy metabolism; Hexavalent chromium; Oxidative stress; Warburg effect

Indexed keywords

ANTIOXIDANT; CELL PROTEIN; CHROMIC ACID; CHROMIUM; GLUCOSE; LACTIC ACID;

BIOENERGY; CARCINOGENICITY; CELL ENERGY; ENERGY METABOLISM; ENERGY TRANSFER; ENZYME ACTIVITY; EPIGENETICS; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; LUNG CANCER; MAMMAL CELL; NONHUMAN; OCCUPATIONAL EXPOSURE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PHENOTYPE; PROTEIN CARBONYLATION; PROTEIN FUNCTION; REVIEW; TRANSACTIVATION; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; LUNG TUMOR; METABOLISM; PATHOLOGY; TOXICITY;

MAMMALIA;

ANIMALS; CHROMATES; CHROMIUM; ENERGY METABOLISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; LUNG NEOPLASMS; METABOLIC NETWORKS AND PATHWAYS; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PHENOTYPE;

EID: 84902545114     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-014-9726-7     Document Type: Review

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