Acquisition of mitochondrial dysregulation and resistance to mitochondrial-mediated apoptosis after genotoxic insult in normal human fibroblasts: A possible model for early stage carcinogenesis

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1823, Issue 2, 2012, Pages 264-272

  Nickens, Kristen P ^a   Han, Ying ^b   Shandilya, Harini ^b   Larrimore, Ashley ^a   Gerard, Gary F ^b   Kaldjian, Eric ^c   Patierno, Steven R ^a   Ceryak, Susan ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^b TRANSGENOMIC INC   (United States)

^c Hearing Health Science   (United States)

Author keywords

Chromium; Death resistance; Early stage carcinogenesis; Genotoxin; Mitochondria

Indexed keywords

CASPASE 3; CHROMIUM; CISPLATIN; CYTOCHROME C; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CLONE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; FIBROBLAST; GENOTOXICITY; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CASPASE 3; CELLS, CULTURED; CHROMIUM; DNA DAMAGE; FIBROBLASTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTAGENS;

EID: 84863403440     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.10.005     Document Type: Article

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