Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 16, 2010, Pages 7455-7460

  Hu, Wenwei ^a   Zhang, Cen ^a   Wu, Rui ^a   Sun, Yvonne ^a   Levine, Arnold ^a,b   Feng, Zhaohui ^a  

^a RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^b INSTITUTE FOR ADVANCED STUDY   (United States)

Author keywords

Oxidative phosphorylation; Reactive oxygen species

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINASE 2; GLUTATHIONE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADENOSINE TRIPHOSPHATE; ANTIOXIDANTS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; KETOGLUTARIC ACIDS; MITOCHONDRIA; OXYGEN; REACTIVE OXYGEN SPECIES; TRANSAMINASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77952212178     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001006107     Document Type: Article

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