Cytochrome b5 plays a key role in human microsomal chromium(VI) reduction

Toxicology

Volumn 159, Issue 3, 2001, Pages 119-133

  Jannetto, Paul J ^a   Antholine, William E ^a   Myers, Charles R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Chromium; Cytochrome b5; P450 reductase; Proteoliposomes

Indexed keywords

ADENOSINE DIPHOSPHATE; CHROMIUM; CYTOCHROME B5; CYTOCHROME P450 REDUCTASE; DEFEROXAMINE; FERRIC CHLORIDE; IRON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; CYTOTOXICITY; DATA ANALYSIS; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; GENOTOXICITY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL; PROTEOLIPOSOME; REDUCTION;

ADENOSINE DIPHOSPHATE; CHROMIUM; CYTOCHROMES B5; DEFEROXAMINE; FERRIC COMPOUNDS; HUMANS; LIPOSOMES; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PROTEOLIPIDS; RECOMBINANT PROTEINS;

EID: 0035961395     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00378-4     Document Type: Article

References (57)

1. Effects of chromium supplementation on urinary Cr excretion of human subjects and correlation of Cr excretion with selected clinical parameters
2. Oxidative damages by iron-chelate complexes depend on the interaction with the target molecules
3. Risk of cancer for arc welders in the Federal Republic of Germany: Results of a second follow up (1983-8)
4. Modification of the erythrocyte anion carrier by chromate
5. Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks
6. Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA
7. Mechanisms of chromium metabolism and genotoxicity
8. Genotoxicity of chromium compounds: A review
9. Mortality study among workers producing chromate pigments in France
10. Intestinal absorption of trace quantities of chromium
11. A simple technique for eliminating interference by detergents in the Lowry method of protein determination
12. 5 reduction by NADPH-cytochrome P450 reductase
13. Electron-transport cytochrome P450 system is involved in the microsomal metabolism of the carcinogen chromate
14. A comparative study of electron transport in microsomes
15. The tagging of red cells and plasma proteins with radioactive chromium
16. Immunohistochemical localization of NADPH-cytochrome P450 reductase in human tissues
17. Incorporation of purified components of the rabbit liver microsomal hydroxylase system into phospholipid vesicles
18. Microsomal reduction of the carcinogen chromate produces chromium(V)
19. 5 from rabbit liver
20. Nephrotoxicity of sodium dichromate depending on the route of administration
21. Chromium
22. Production of activated species of oxygen during the chromate(VI)-ascorbate reaction: Implication in carcinogenesis
23. 2+-ATPase: Mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents
24. Carcinogenicity and mutagenicity of chromium compounds: The association between bronchial metaplasia and neoplasia
25. 5 gene
26. Protein measurement with the Folin phenol reagent
27. Chromium(IV)-mediated Fentonlike reaction causes DNA damage: Implication to genotoxicity of chromate
28. Microsomal metabolism of hexavalent chromium. Inhibitory effect of oxygen and involvement of cytochrome P450
29. Direct evidence for hydroxyl radical-induced damage to nucleic acids by chromium(VI)-derived species
30. Superoxide generation by NADPH-cytochrome P450 reductase: The effect of iron chelators and the role of superoxide in microsomal lipid peroxidation
31. Cell-cycle-specific oscillation in the composition of chromatophore membrane in Rhodospirillum rubrum
32. Iron stimulates the rate of reduction of hexavalent chromium by human microsomes
33. Antibodies to a synthetic peptide that react with flavin-containing monooxygenase (HLFM03) in human hepatic microsomes
34. Naphthoquinones stimulate the rate of reduction of hexavalent chromium by human microsomes
35. Reduction of chromium(VI) to chromium(V) by human microsomal enzymes: Effects of iron and quinones
36. Isolation and sequence of omcA, a gene encoding a decaheme outer membrane cytochrome c of Shewanella putrefaciens MR-1, and detection of omcA homologs in other strains of S. putrefaciens
37. The carbon monoxide binding pigment of liver microsomes
38. 5 in the reductive metabolism of 3′-azido-3′-deoxythymidine (AZT) to 3′-amino-3′-deoxythymidine
39. Enzymatic reduction of chromium(VI) by human hepatic microsomes
40. Incorporation of bacteriorhodopsin into large unilamellar liposomes by reverse phase evaporation
41. Mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. 2. Incorporation of the light-driven proton pump bacteriorhodopsin
42. NADPH-dependent flavoenzymes catalyze one electron reduction of metal ions and molecular oxygen and generate hydroxyl radicals
43. On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species
44. The role of superoxide radical in chromium(VI)-generated hydroxyl radical: The Cr(VI) Haber-Weiss cycle
45. One electron reduction of carcinogen chromate by microsomes, mitochondria and E. coli: Identification of Cr(V) and OH radical
46. Is there a role for reactive oxygen species in the mechanism of chromium(VI) carcinogenesis?
47. Reaction of chromium(VI) with ascorbate produces chromium(V), chromium(IV), and carbon-based radicals
48. Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation
49. 2 in Chinese hamster V79 cells
50. Organ toxicity of chromium
51. The interaction of chromium with nucleic acids
52. Chromium(VI)-induced DNA lesions and chromium distribution on rat kidney, liver and lung
53. Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states
54. 3+ chelates and ferritin: Enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen
55. Two monoclonal antibodies recognizing different epitopes on rat cytochrome IIB1 react with human IIE1
56. 5 in NADH-dependent microsomal reduction of ferric complexes, lipid peroxidation, and hydrogen peroxide generation
57. 2 generation, and ferric reduction