Novel insights into the neurobiology underlying LRRK2-linked Parkinson's disease

Neuropharmacology

Volumn 85, Issue , 2014, Pages 45-56

  Gomez Suaga P ^a   Fdez, E ^a   Fernandez B ^a   Martinez Salvador M ^a   Blanca Ramirez M ^a   Madero Perez J ^a   Rivero Rios P ^a   Fuentes, J M ^b   Hilfiker, S ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Autophagy; Endocytosis; GTPase; Inhibitor; Kinase; LRRK2; Neuronal dysfunction; Parkinson's disease; Rab protein; Vesicle trafficking

Indexed keywords

CALCIUM; LEUCINE RICH REPEAT KINASE 2; LEUCINE RICH REPEAT KINASE 2 INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; RAB PROTEIN; UNCLASSIFIED DRUG; LRRK2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

CALCIUM HOMEOSTASIS; DRUG TARGETING; ENZYME ACTIVITY; GENE MUTATION; HUMAN; MEMBRANE TRANSPORT; MISSENSE MUTATION; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SYNAPSE; ANIMAL; BIOLOGICAL MODEL; ENZYMOLOGY; GENETICS; METABOLISM;

ANIMALS; HUMANS; MODELS, NEUROLOGICAL; PARKINSON DISEASE; PROTEIN-SERINE-THREONINE KINASES; SYNAPSES;

EID: 84902152511     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.05.020     Document Type: Review

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