Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 7, 2014, Pages 2626-2631

  Beilina, Alexandria ^a   Rudenko, Iakov N ^a   Kaganovich, Alice ^a   Civiero, Laura ^b   Chau, Hien ^c   Kalia, Suneil K ^d   Kalia, Lorraine V ^e   Lobbestael, Evy ^f   Chia, Ruth ^a   Ndukwe, Kelechi ^a   Ding, Jinhui ^g   Nalls, Mike A ^h   Olszewski, Maciej ⁱ   Hauser, David N ^j   Kumaran, Ravindran ^a   Lozano, Andres M ^d   Baekelandt, Veerle ^f   Greene, Lois E ⁱ   Taymans, Jean Marc ^f   Greggio, Elisa ^b   Cookson, Mark R ^a   more..

^a Cell Biology and Gene Expression Section   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c Division of Brain   (Canada)

^d Division of Neurosurgery   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g Laboratory of Neurogenetics ^*  (Canada)

^h NATIONAL INSTITUTE ON AGING   (United States)

ⁱ NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^j BROWN UNIVERSITY   (United States)

more..

Author keywords

Autophagy; BAG5; GAK; Trans Golgi

Indexed keywords

LEUCINE RICH REPEAT KINASE 2;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; COMPLEX FORMATION; CYCLIN G ASSOCIATED KINASE GENE; GENE; GENE FUNCTION; GENE MUTATION; LYSOSOME; MOUSE; NONHUMAN; ONCOGENE RAS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAB7L1 GENE;

AUTOPHAGY; BAG5; GAK; TRANS-GOLGI;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANALYSIS OF VARIANCE; BLOTTING, WESTERN; BRAIN; CELL FRACTIONATION; DNA PRIMERS; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GOLGI APPARATUS; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MASS SPECTROMETRY; MICROSCOPY, CONFOCAL; MULTIPROTEIN COMPLEXES; PARKINSON DISEASE; PLASMIDS; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES; RAB GTP-BINDING PROTEINS; TRANSPORT VESICLES;

EID: 84894322830     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1318306111     Document Type: Article

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