GTPase activity plays a key role in the pathobiology of LRRK2

PLoS Genetics

Volumn 6, Issue 4, 2010, Pages

  Xiong, Yulan ^a   Coombes, Candice E ^a   Kilaru, Austin ^b   Li, Xiaojie ^a   Gitler, Aaron D ^b   Bowers, William J ^c   Dawson, Valina L ^a   Dawson, Ted M ^a   Moore, Darren J ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; GUANOSINE TRIPHOSPHATASE; LEUCINE RICH REPEAT KINASE 2; LRRK2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME REGULATION; FETUS; GENOME ANALYSIS; MOUSE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN VARIANT; SACCHAROMYCES CEREVISIAE; FUNGAL GENOME; GENETICS; HUMAN; METABOLISM; MUTATION; NERVE CELL; PROTEIN TERTIARY STRUCTURE;

SACCHAROMYCES CEREVISIAE;

GENOME, FUNGAL; GTP PHOSPHOHYDROLASES; HUMANS; MUTATION; NEURONS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE;

EID: 77952391573     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000902     Document Type: Article

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