Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Biochemical Journal

Volumn 453, Issue 1, 2013, Pages 101-113

  Davies, Paul ^a   Hinkle, Kelly M ^b   Sukar, Nour N ^c   Sepulveda, Bryan ^d   Mesias, Roxana ^d   Serrano, Geidy ^e   Alessi, Dario R ^a   Beach, Thomas G ^e   Benson, Deanna L ^d   White III, Charles L ^f   Cowell, Rita M ^g   Das, Sonal S ^h   West, Andrew B ^c   Melros, Heather L ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b MAYO GRADUATE SCHOOL   (United States)

^c The University of Alabama at Birmingham   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e SUN HEALTH RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^h THE MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH   (United States)

Author keywords

Immunohistochemistry; Kinase assay; Leucine rich repeat kinase 2 (LRRK2); Parkinson's disease

Indexed keywords

LEUCINE RICH REPEAT KINASE 2; MONOCLONAL ANTIBODY; PHOSPHOTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN; CELL LINE; EPITOPE MAPPING; HUMANS; IMMUNOBLOTTING; MALE; MICE; MICE, KNOCKOUT; PARKINSON DISEASE; PROTEIN-SERINE-THREONINE KINASES; RABBITS; RATS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RATTUS; RODENTIA;

EID: 84879024830     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121742     Document Type: Article

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