Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Krabbe, Grietje ^a,d   Halle, Annett ^b,c   Matyash, Vitali ^a   Rinnenthal, Jan L ^b   Eom, Gina D ^b   Bernhardt, Ulrike ^b   Miller, Kelly R ^b   Prokop, Stefan ^b   Kettenmann, Helmut ^a   Heppner, Frank L ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

^d GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SLICE; CELL MOTILITY; CONFOCAL MICROSCOPY; DISEASE COURSE; FUNCTIONAL DISEASE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MICROGLIA; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL MOVEMENT; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROGLIA; MUTATION; PHAGOCYTOSIS; PLAQUE, AMYLOID; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; SPATIO-TEMPORAL ANALYSIS;

ANIMALIA; MUS;

EID: 84876006819     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060921     Document Type: Article

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