Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer's Disease

Neuron

Volumn 79, Issue 5, 2013, Pages 873-886

  Lucin, KurtM ^a,b   O'Brien, CaitlinE ^a,b   Bieri, Gregor ^a,b   Czirr, Eva ^a,b   Mosher, KiraI ^a,b   Abbey, RachelleJ ^a,b   Mastroeni, DiegoF ^c   Rogers, Joseph ^d   Spencer, Brian ^e   Masliah, Eliezer ^e,f   Wyss Coray, Tony ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c SUN HEALTH RESEARCH INSTITUTE   (United States)

^d SRI INTERNATIONAL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; CD36 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; RECEPTOR; RETROMER PROTEIN; TREM2 PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIGENS, CD36; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BRAIN; CELL LINE; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICROGLIA; PHAGOCYTOSIS; RECEPTORS, IMMUNOLOGIC; VESICULAR TRANSPORT PROTEINS;

EID: 84884185631     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2013.06.046     Document Type: Article

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