-
1
-
-
84886496878
-
Role of STAT3 in cancer metastasis and translational advances
-
doi:10.1155/2013/421821
-
Kamran, M.Z.; Patil, P.; Gude, R.P. Role of STAT3 in cancer metastasis and translational advances. Biomed. Res. Int. 2013, 2013, doi:10.1155/2013/421821.
-
(2013)
Biomed. Res. Int
, vol.2013
-
-
Kamran, M.Z.1
Patil, P.2
Gude, R.P.3
-
2
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P.C.; Behrmann, I.; Muller-Newen, G.; Schaper, F.; Graeve, L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 1998, 334, 297-314.
-
(1998)
Biochem. J
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Muller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
3
-
-
0037443661
-
Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
-
Niemand, C.; Nimmesgern, A.; Haan, S.; Fischer, P.; Schaper, F.; Rossaint, R.; Heinrich, P.C.; Muller-Newen, G. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J. Immunol. 2003, 170, 3263-3272.
-
(2003)
J. Immunol
, vol.170
, pp. 3263-3272
-
-
Niemand, C.1
Nimmesgern, A.2
Haan, S.3
Fischer, P.4
Schaper, F.5
Rossaint, R.6
Heinrich, P.C.7
Muller-Newen, G.8
-
4
-
-
0033968596
-
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR
-
Yokogami, K.; Wakisaka, S.; Avruch, J.; Reeves, S.A. Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR. Curr. Biol. 2000, 10, 47-50.
-
(2000)
Curr. Biol
, vol.10
, pp. 47-50
-
-
Yokogami, K.1
Wakisaka, S.2
Avruch, J.3
Reeves, S.A.4
-
5
-
-
79953208248
-
STAT3 signaling: Anticancer strategies and challenges
-
Johnston, P.A.; Grandis, J.R. STAT3 signaling: Anticancer strategies and challenges. Mol. Interv. 2011, 11, 18-26.
-
(2011)
Mol. Interv
, vol.11
, pp. 18-26
-
-
Johnston, P.A.1
Grandis, J.R.2
-
6
-
-
7944233465
-
Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis
-
Silva, C.M. Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis. Oncogene 2004, 23, 8017-8023.
-
(2004)
Oncogene
, vol.23
, pp. 8017-8023
-
-
Silva, C.M.1
-
7
-
-
0035952638
-
G protein coupled receptor signaling through the Src and STAT3 pathway: Role in proliferation and transformation
-
Ram, P.T.; Iyengar, R. G protein coupled receptor signaling through the Src and STAT3 pathway: Role in proliferation and transformation. Oncogene 2001, 20, 1601-1606.
-
(2001)
Oncogene
, vol.20
, pp. 1601-1606
-
-
Ram, P.T.1
Iyengar, R.2
-
8
-
-
0032746702
-
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein
-
Turkson, J.; Turkson, J.; Bowman, T.; Adnane, J.; Zhang, Y.; Djeu, J.Y.; Sekharam, M.; Frank, D.A.; Holzman, L.B.; Wu, J. et al. Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein. Mol. Cell. Biol. 1999, 19, 7519-7528.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 7519-7528
-
-
Turkson, J.1
Turkson, J.2
Bowman, T.3
Adnane, J.4
Zhang, Y.5
Djeu, J.Y.6
Sekharam, M.7
Frank, D.A.8
Holzman, L.B.9
Wu, J.10
-
9
-
-
0030772458
-
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
-
Chung, J.; Uchida, E.; Grammer, T.C.; Blenis, J. STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol. Cell. Biol. 1997, 17, 6508-6516.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 6508-6516
-
-
Chung, J.1
Uchida, E.2
Grammer, T.C.3
Blenis, J.4
-
10
-
-
0006603039
-
Serine phosphorylation and negative regulation of STAT3 by JNK
-
Lim, C.P.; Cao, X. Serine phosphorylation and negative regulation of STAT3 by JNK. J. Biol. Chem. 1999, 274, 31055-31061.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 31055-31061
-
-
Lim, C.P.1
Cao, X.2
-
11
-
-
0033588229
-
Protein kinase C delta associates with and phosphorylates STAT3 in an interleukin-6-dependent manner
-
Jain, N.; Zhang, T.; Kee, W.H.; Li, W.; Cao, X. Protein kinase C delta associates with and phosphorylates STAT3 in an interleukin-6-dependent manner. J. Biol. Chem. 1999, 274, 24392-24400.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 24392-24400
-
-
Jain, N.1
Zhang, T.2
Kee, W.H.3
Li, W.4
Cao, X.5
-
12
-
-
33646365075
-
Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements
-
Ma, J.; Cao, X. Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. Cell. Signal. 2006, 18, 1117-1126.
-
(2006)
Cell. Signal
, vol.18
, pp. 1117-1126
-
-
Ma, J.1
Cao, X.2
-
13
-
-
84868693885
-
Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
-
Subramaniam, A.; Shanmugam, M.K.; Perumal, E.; Li, F.; Nachiyappan, A.; Dai, X.; Swamy, S.N.; Ahn, K.S.; Kumar, A.P.; Tan, B.K. et al. Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma. Biochim. Biophys. Acta 2013, 1835, 46-60.
-
(2013)
Biochim. Biophys. Acta
, vol.1835
, pp. 46-60
-
-
Subramaniam, A.1
Shanmugam, M.K.2
Perumal, E.3
Li, F.4
Nachiyappan, A.5
Dai, X.6
Swamy, S.N.7
Ahn, K.S.8
Kumar, A.P.9
Tan, B.K.10
-
14
-
-
18844444774
-
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
-
Gray, M.J.; Zhang, J.; Ellis, L.M.; Semenza, G.L.; Evans, D.B.; Watowich, S.S.; Gallick, G.E. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 2005, 24, 3110-3120.
-
(2005)
Oncogene
, vol.24
, pp. 3110-3120
-
-
Gray, M.J.1
Zhang, J.2
Ellis, L.M.3
Semenza, G.L.4
Evans, D.B.5
Watowich, S.S.6
Gallick, G.E.7
-
15
-
-
0037040924
-
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a
-
Giraud, S.; Bienvenu, F.; Avril, S.; Gascan, H.; Heery, D.M.; Coqueret, O. Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. J. Biol. Chem. 2002, 277, 8004-8011.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 8004-8011
-
-
Giraud, S.1
Bienvenu, F.2
Avril, S.3
Gascan, H.4
Heery, D.M.5
Coqueret, O.6
-
16
-
-
79955623599
-
Signal transducer and activator of transcription 3 (STAT3): A promising target for anticancer therapy
-
Masciocchi, D.; Gelain, A.; Villa, S.; Meneghetti, F.; Barlocco, D. Signal transducer and activator of transcription 3 (STAT3): A promising target for anticancer therapy. Future Med. Chem. 2011, 3, 567-597.
-
(2011)
Future Med. Chem
, vol.3
, pp. 567-597
-
-
Masciocchi, D.1
Gelain, A.2
Villa, S.3
Meneghetti, F.4
Barlocco, D.5
-
17
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa, H.; Ohishi, M.; Mori, H.; Murakami, M.; Chinen, T.; Aki, D.; Hanada, T.; Takeda, K.; Akira, S.; Hoshijima, M. et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat. Immunol. 2003, 4, 551-556.
-
(2003)
Nat. Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
Hanada, T.7
Takeda, K.8
Akira, S.9
Hoshijima, M.10
-
18
-
-
41849116690
-
Roles of unphosphorylated STATs in signaling
-
Yang, J.; Stark, G.R. Roles of unphosphorylated STATs in signaling. Cell. Res. 2008, 18, 443-451.
-
(2008)
Cell. Res
, vol.18
, pp. 443-451
-
-
Yang, J.1
Stark, G.R.2
-
19
-
-
0036797750
-
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB
-
Yu, Z.; Zhang, W.; Kone, B.C. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem. J. 2002, 367, 97-105.
-
(2002)
Biochem. J
, vol.367
, pp. 97-105
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
20
-
-
84879459053
-
Molecular pathogenesis and progression of prostate cancer
-
Schrecengost, R.; Knudsen, K.E. Molecular pathogenesis and progression of prostate cancer. Semin. Oncol. 2013, 40, 244-258.
-
(2013)
Semin. Oncol
, vol.40
, pp. 244-258
-
-
Schrecengost, R.1
Knudsen, K.E.2
-
21
-
-
0030741380
-
Hyperactive androgen receptor in prostate cancer: What does it mean for new therapy concepts?
-
Culig, Z.; Hobisch, A.; Hittmair, A.; Peterziel, H.; Radmayr, C.; Bartsch, G.; Cato, A.C.; Klocker, H. Hyperactive androgen receptor in prostate cancer: What does it mean for new therapy concepts? Histol. Histopathol. 1997, 12, 781-786.
-
(1997)
Histol. Histopathol
, vol.12
, pp. 781-786
-
-
Culig, Z.1
Hobisch, A.2
Hittmair, A.3
Peterziel, H.4
Radmayr, C.5
Bartsch, G.6
Cato, A.C.7
Klocker, H.8
-
22
-
-
0032883932
-
Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system
-
Culig, Z.; Hoffmann, J.; Erdel, M.; Eder, I.E.; Hobisch, A.; Hittmair, A.; Bartsch, G.; Utermann, G.; Schneider, M.R.; Parczyk, K. et al. Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system. Br. J. Cancer 1999, 81, 242-251.
-
(1999)
Br. J. Cancer
, vol.81
, pp. 242-251
-
-
Culig, Z.1
Hoffmann, J.2
Erdel, M.3
Eder, I.E.4
Hobisch, A.5
Hittmair, A.6
Bartsch, G.7
Utermann, G.8
Schneider, M.R.9
Parczyk, K.10
-
23
-
-
84891052481
-
Genomic rearrangements of in prostate cancer
-
Phin, S.; Moore, M.W.; Cotter, P.D. Genomic rearrangements of in prostate cancer. Front. Oncol. 2013, 3, e240.
-
(2013)
Front. Oncol
, vol.3
-
-
Phin, S.1
Moore, M.W.2
Cotter, P.D.3
-
24
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver, B.S.; Chapinski, C.; Wongvipat, J.; Hieronymus, H.; Chen, Y.; Chandarlapaty, S.; Arora, V.K.; Le, C.; Koutcher, J.; Scher, H. et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 2011, 19, 575-586.
-
(2011)
Cancer Cell
, vol.19
, pp. 575-586
-
-
Carver, B.S.1
Chapinski, C.2
Wongvipat, J.3
Hieronymus, H.4
Chen, Y.5
Chandarlapaty, S.6
Arora, V.K.7
Le, C.8
Koutcher, J.9
Scher, H.10
-
25
-
-
79952393630
-
Cooperation between STAT3 and AKT signaling leads to prostate tumor development in transgenic mice
-
Blando, J.M.; Carbajal, S.; Abel, E.; Beltran, L.; Conti, C.; Fischer, S.; DiGiovanni, J. Cooperation between STAT3 and AKT signaling leads to prostate tumor development in transgenic mice. Neoplasia 2011, 13, 254-265.
-
(2011)
Neoplasia
, vol.13
, pp. 254-265
-
-
Blando, J.M.1
Carbajal, S.2
Abel, E.3
Beltran, L.4
Conti, C.5
Fischer, S.6
Digiovanni, J.7
-
26
-
-
84886389273
-
Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues
-
Smith, D.A.; Kiba, A.; Zong, Y.; Witte, O.N. Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues. Mol. Cancer Res. 2013, 11, 1159-1165.
-
(2013)
Mol. Cancer Res
, vol.11
, pp. 1159-1165
-
-
Smith, D.A.1
Kiba, A.2
Zong, Y.3
Witte, O.N.4
-
27
-
-
80052461278
-
Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition
-
Martin, P.; Liu, Y.N.; Pierce, R.; Abou-Kheir, W.; Casey, O.; Seng, V.; Camacho, D.; Simpson, R.M.; Kelly, K. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. Am. J. Pathol. 2011, 179, 422-435.
-
(2011)
Am. J. Pathol
, vol.179
, pp. 422-435
-
-
Martin, P.1
Liu, Y.N.2
Pierce, R.3
Abou-Kheir, W.4
Casey, O.5
Seng, V.6
Camacho, D.7
Simpson, R.M.8
Kelly, K.9
-
28
-
-
84873530895
-
Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage
-
Li, L.; Xie, H.; Liang, L.; Gao, Y.; Zhang, D.; Fang, L.; Lee, S.O.; Luo, J.; Chen, X.; Wang, X. et al. Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage. Carcinogenesis 2013, 34, 257-267.
-
(2013)
Carcinogenesis
, vol.34
, pp. 257-267
-
-
Li, L.1
Xie, H.2
Liang, L.3
Gao, Y.4
Zhang, D.5
Fang, L.6
Lee, S.O.7
Luo, J.8
Chen, X.9
Wang, X.10
-
29
-
-
79952763967
-
PrLZ protects prostate cancer cells from apoptosis induced by androgen deprivation via the activation of Stat3/Bcl-2 pathway
-
Zhang, D.; He, D.; Xue, Y.; Wang, R.; Wu, K.; Xie, H.; Zeng, J.; Wang, X.; Zhau, H.E.; Chung, L.W. et al. PrLZ protects prostate cancer cells from apoptosis induced by androgen deprivation via the activation of Stat3/Bcl-2 pathway. Cancer Res. 2011, 71, 2193-2202.
-
(2011)
Cancer Res
, vol.71
, pp. 2193-2202
-
-
Zhang, D.1
He, D.2
Xue, Y.3
Wang, R.4
Wu, K.5
Xie, H.6
Zeng, J.7
Wang, X.8
Zhau, H.E.9
Chung, L.W.10
-
30
-
-
84884212418
-
Expression of Id proteins is regulated by the Bcl-3 proto-oncogene in prostate cancer
-
Ahlqvist, K.; Saamarthy, K.; Syed Khaja, A.S.; Bjartell, A.; Massoumi, R. Expression of Id proteins is regulated by the Bcl-3 proto-oncogene in prostate cancer. Oncogene 2013, 32, 1601-1608.
-
(2013)
Oncogene
, vol.32
, pp. 1601-1608
-
-
Ahlqvist, K.1
Saamarthy, K.2
Syed Khaja, A.S.3
Bjartell, A.4
Massoumi, R.5
-
31
-
-
55349110263
-
Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice
-
Lee, C.; Dhillon, J.; Wang, M.Y.; Gao, Y.; Hu, K.; Park, E.; Astanehe, A.; Hung, M.C.; Eirew, P.; Eaves, C.J. et al. Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice. Cancer Res. 2008, 68, 8661-8666.
-
(2008)
Cancer Res
, vol.68
, pp. 8661-8666
-
-
Lee, C.1
Dhillon, J.2
Wang, M.Y.3
Gao, Y.4
Hu, K.5
Park, E.6
Astanehe, A.7
Hung, M.C.8
Eirew, P.9
Eaves, C.J.10
-
32
-
-
84877134575
-
YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α
-
Takeuchi, A.; Shiota, M.; Tatsugami, K.; Yokomizo, A.; Kuroiwa, K.; Dejima, T.; Tanaka, S.; Itsumi, M.; Eto, M.; Naito, S. YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α. Cancer Immunol. Immunother. 2013, 62, 517-527.
-
(2013)
Cancer Immunol. Immunother
, vol.62
, pp. 517-527
-
-
Takeuchi, A.1
Shiota, M.2
Tatsugami, K.3
Yokomizo, A.4
Kuroiwa, K.5
Dejima, T.6
Tanaka, S.7
Itsumi, M.8
Eto, M.9
Naito, S.10
-
33
-
-
80052161751
-
Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression
-
Shiota, M.; Takeuchi, A.; Song, Y.; Yokomizo, A.; Kashiwagi, E.; Uchiumi, T.; Kuroiwa, K.; Tatsugami, K.; Fujimoto, N.; Oda, Y. et al. Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression. Endocr. Relat. Cancer 2011, 18, 505-517.
-
(2011)
Endocr. Relat. Cancer
, vol.18
, pp. 505-517
-
-
Shiota, M.1
Takeuchi, A.2
Song, Y.3
Yokomizo, A.4
Kashiwagi, E.5
Uchiumi, T.6
Kuroiwa, K.7
Tatsugami, K.8
Fujimoto, N.9
Oda, Y.10
-
34
-
-
0033911711
-
Serum interleukin 6 as a prognostic factor in patients with prostate cancer
-
Nakashima, J.; Tachibana, M.; Horiguchi, Y.; Oya, M.; Ohigashi, T.; Asakura, H.; Murai, M. Serum interleukin 6 as a prognostic factor in patients with prostate cancer. Clin. Cancer Res. 2000, 6, 2702-2706.
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 2702-2706
-
-
Nakashima, J.1
Tachibana, M.2
Horiguchi, Y.3
Oya, M.4
Ohigashi, T.5
Asakura, H.6
Murai, M.7
-
35
-
-
0032830265
-
Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma
-
Adler, H.L.; McCurdy, M.A.; Kattan, M.W.; Timme, T.L.; Scardino, P.T.; Thompson, T.C. Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma. J. Urol. 1999, 161, 182-187.
-
(1999)
J. Urol
, vol.161
, pp. 182-187
-
-
Adler, H.L.1
McCurdy, M.A.2
Kattan, M.W.3
Timme, T.L.4
Scardino, P.T.5
Thompson, T.C.6
-
36
-
-
0028820721
-
Interleukin-6: A candidate mediator of human prostate cancer morbidity
-
Twillie, D.A.; Eisenberger, M.A.; Carducci, M.A.; Hseih, W.S.; Kim, W.Y.; Simons, J.W Interleukin-6: A candidate mediator of human prostate cancer morbidity. Urology 1995, 45, 542-549
-
(1995)
Urology
, vol.45
, pp. 542-549
-
-
Twillie, D.A.1
Eisenberger, M.A.2
Carducci, M.A.3
Hseih, W.S.4
Kim, W.Y.5
Simons, J.W.6
-
37
-
-
0036510548
-
Activation of the androgen receptor N-terminal domai by interleukin-6 via MAPK and STAT3 signal transduction pathways
-
Ueda, T.; Bruchovsky, N.; Sadar, M.D. Activation of the androgen receptor N-terminal domai by interleukin-6 via MAPK and STAT3 signal transduction pathways. J. Biol. Chem. 2002, 27 7076-7085.
-
(2002)
J. Biol. Chem
, vol.27
, pp. 7076-7085
-
-
Ueda, T.1
Bruchovsky, N.2
Sadar, M.D.3
-
38
-
-
79952830388
-
Involvement of interleukin-6 and androgen receptor signaling in pancreatic cancer
-
Okitsu, K.; Kanda, T.; Imazeki, F.; Yonemitsu, Y.; Ray, R.B.; Chang, C.; Yokosuka, O Involvement of interleukin-6 and androgen receptor signaling in pancreatic cancer. Genes Cance 2010, 1, 859-867.
-
(2010)
Genes Cance
, vol.1
, pp. 859-867
-
-
Okitsu, K.1
Kanda, T.2
Imazeki, F.3
Yonemitsu, Y.4
Ray, R.B.5
Chang, C.6
Yokosuka, O.7
-
39
-
-
0034651796
-
STAT3 mediates IL-6-induced neuroendocrine differentiation i prostate cancer cells
-
Spiotto, M.T.; Chung, T.D. STAT3 mediates IL-6-induced neuroendocrine differentiation i prostate cancer cells. Prostate 2000, 42, 186-195.
-
(2000)
Prostate
, vol.42
, pp. 186-195
-
-
Spiotto, M.T.1
Chung, T.D.2
-
40
-
-
21344441226
-
P300 Regulate androgen receptor-independent expression of prostate-specific antigen in prostate cancer cel treated chronically with interleukin-6
-
Debes, J.D.; Comuzzi, B.; Schmidt, L.J.; Dehm, S.M.; Culig, Z.; Tindall, D.J. P300 Regulate androgen receptor-independent expression of prostate-specific antigen in prostate cancer cel treated chronically with interleukin-6. Cancer Res. 2005, 65, 5965-5973.
-
(2005)
Cancer Res
, vol.65
, pp. 5965-5973
-
-
Debes, J.D.1
Comuzzi, B.2
Schmidt, L.J.3
Dehm, S.M.4
Culig, Z.5
Tindall, D.J.6
-
41
-
-
0034817053
-
Culig, Prostate cancer cells (LNCaP) generated after long-term interleukin 6 (IL-6) treatment expre IL-6 and acquire an IL-6 partially resistant phenotype
-
Hobisch, A.; Ramoner, R.; Fuchs, D.; Godoy-Tundidor, S.; Bartsch, G.; Klocker, H.; Culig, Prostate cancer cells (LNCaP) generated after long-term interleukin 6 (IL-6) treatment expre IL-6 and acquire an IL-6 partially resistant phenotype. Clin. Cancer Res. 2001, 7, 2941-2948.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 2941-2948
-
-
Hobisch, A.1
Ramoner, R.2
Fuchs, D.3
Godoy-Tundidor, S.4
Bartsch, G.5
Klocker, H.6
-
42
-
-
0034901655
-
Interleukin-6 induces androgen responsivene in prostate cancer cells through up-regulation of androgen receptor expression
-
Lin, D.L.; Whitney, M.C.; Yao, Z.; Keller, E.T. Interleukin-6 induces androgen responsivene in prostate cancer cells through up-regulation of androgen receptor expression. Clin. Cancer Re 2001, 7, 1773-1781.
-
(2001)
Clin. Cancer Re
, vol.7
, pp. 1773-1781
-
-
Lin, D.L.1
Whitney, M.C.2
Yao, Z.3
Keller, E.T.4
-
43
-
-
84864283846
-
LNCaP prostate cancer cells wit autocrine interleukin-6 expression are resistant to IL-6-induced neuroendocrine differentiatio due to increased expression of suppressors of cytokine signaling
-
Ge, D.; Gao, A.C.; Zhang, Q.; Liu, S.; Xue, Y.; You, Z. LNCaP prostate cancer cells wit autocrine interleukin-6 expression are resistant to IL-6-induced neuroendocrine differentiatio due to increased expression of suppressors of cytokine signaling. Prostate 2012, 72, 1306-1316
-
(2012)
Prostate
, vol.72
, pp. 1306-1316
-
-
Ge, D.1
Gao, A.C.2
Zhang, Q.3
Liu, S.4
Xue, Y.5
You, Z.6
-
44
-
-
77549083560
-
Dangerous liaisons: STAT3 and NF-κB collaboration and crosstal in cancer
-
Grivennikov, S.I.; Karin, M. Dangerous liaisons: STAT3 and NF-κB collaboration and crosstal in cancer. Cytokine Growth Factor Rev. 2010, 21, 11-19.
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, pp. 11-19
-
-
Grivennikov, S.I.1
Karin, M.2
-
45
-
-
63249092765
-
Persistently activated STAT3 maintains constitutive NF-kappaB activity i tumors
-
Lee, H.; Herrmann, A.; Deng, J.H.; Kujawski, M.; Niu, G.; Li, Z.; Forman, S.; Jove, R Pardoll, D.M.; Yu, H. Persistently activated STAT3 maintains constitutive NF-kappaB activity i tumors. Cancer Cell. 2009, 15, 283-293.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
Forman, S.7
Jove, R.8
Pardoll, D.M.9
Yu, H.10
-
46
-
-
84891160894
-
Inhibition of constitutively activ Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells
-
Liu, C.; Zhu, Y.; Lou, W.; Cui, Y.; Evans, C.P.; Gao, A.C. Inhibition of constitutively activ Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells. Prostate 201 74, 201-209.
-
Prostate 201
, vol.74
, pp. 201-209
-
-
Liu, C.1
Zhu, Y.2
Lou, W.3
Cui, Y.4
Evans, C.P.5
Gao, A.C.6
-
47
-
-
84882274167
-
NF-kappaB2/p5 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variant
-
Nadiminty, N.; Tummala, R.; Liu, C.; Yang, J.; Lou, W.; Evans, C.P.; Gao, A.C. NF-kappaB2/p5 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variant Mol. Cancer Ther. 2013, 12, 1629-1637.
-
(2013)
Mol. Cancer Ther
, vol.12
, pp. 1629-1637
-
-
Nadiminty, N.1
Tummala, R.2
Liu, C.3
Yang, J.4
Lou, W.5
Evans, C.P.6
Gao, A.C.7
-
48
-
-
84861611628
-
NF-κB signaling in prosta cancer: A promising therapeutic target? World
-
Jain, G.; Cronauer, M.V.; Schrader, M.; Moller, P.; Marienfeld, R.B. NF-κB signaling in prosta cancer: A promising therapeutic target? World J. Urol. 2012, 30, 303-310.
-
(2012)
J. Urol
, vol.30
, pp. 303-310
-
-
Jain, G.1
Cronauer, M.V.2
Schrader, M.3
Moller, P.4
Marienfeld, R.B.5
-
49
-
-
84866324123
-
Cancer stem cells and epithelial-mesenchymal transition: Concep and molecular links
-
doi:10.1016/j.semcancer
-
Scheel, C.; Weinberg, R.A. Cancer stem cells and epithelial-mesenchymal transition: Concep and molecular links. Semin. Cancer Biol. 2012, doi:10.1016/j.semcancer.
-
(2012)
Semin. Cancer Biol
-
-
Scheel, C.1
Weinberg, R.A.2
-
50
-
-
84890275857
-
Prostate cancer originating in basal cells progresses t adenocarcinoma propagated by luminal-like cells
-
Stoyanova, T.; Cooper, A.R.; Drake, J.M.; Liu, X.; Armstrong, A.J.; Pienta, K.J.; Zhang, H Kohn, D.B.; Huang, J.; Witte, O.N. et al. Prostate cancer originating in basal cells progresses t adenocarcinoma propagated by luminal-like cells. Proc. Natl. Acad. Sci. USA 2013, 11 20111-20116.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.11
, pp. 20111-20116
-
-
Stoyanova, T.1
Cooper, A.R.2
Drake, J.M.3
Liu, X.4
Armstrong, A.J.5
Pienta, K.J.6
Zhang, H.7
Kohn, D.B.8
Huang, J.9
Witte, O.N.10
-
51
-
-
84855484465
-
Molecular classification of prostate cancer using curated expression signatures
-
Markert, E.K.; Mizuno, H.; Vazquez, A.; Levine, A.J. Molecular classification of prostate cancer using curated expression signatures. Proc. Natl. Acad. Sci. USA 2011, 108, 21276-21281.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 21276-21281
-
-
Markert, E.K.1
Mizuno, H.2
Vazquez, A.3
Levine, A.J.4
-
52
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh, A.; Settleman, J. EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer. Oncogene 2010, 29, 4741-4751.
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
53
-
-
84874299107
-
New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells
-
Lee, S.O.; Ma, Z.; Yeh, C.R.; Luo, J.; Lin, T.H.; Lai, K.P.; Yamashita, S.; Liang, L.; Tian, J.; Li, L. et al. New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells. J. Mol. Cell. Biol. 2013, 5, 14-26.
-
(2013)
J. Mol. Cell. Biol
, vol.5
, pp. 14-26
-
-
Lee, S.O.1
Ma, Z.2
Yeh, C.R.3
Luo, J.4
Lin, T.H.5
Lai, K.P.6
Yamashita, S.7
Liang, L.8
Tian, J.9
Li, L.10
-
54
-
-
84865839326
-
Epithelial-mesenchymal transitions: Insights from development
-
Lim, J.; Thiery, J.P. Epithelial-mesenchymal transitions: Insights from development. Development 2012, 139, 3471-3486.
-
(2012)
Development
, vol.139
, pp. 3471-3486
-
-
Lim, J.1
Thiery, J.P.2
-
55
-
-
80051703400
-
Epithelial-to-mesenchymal transition in prostate cancer: Paradigm or puzzle
-
Nauseef, J.T.; Henry, M.D. Epithelial-to-mesenchymal transition in prostate cancer: Paradigm or puzzle? Nat. Rev. Urol. 2011, 8, 428-439.
-
(2011)
Nat. Rev. Urol
, vol.8
, pp. 428-439
-
-
Nauseef, J.T.1
Henry, M.D.2
-
56
-
-
77953576511
-
N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
-
Jennbacken, K.; Tesan, T.; Wang, W.; Gustavsson, H.; Damber, J.E.; Welen, K. N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer. Endocr. Relat. Cancer 2010, 17, 469-479.
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 469-479
-
-
Jennbacken, K.1
Tesan, T.2
Wang, W.3
Gustavsson, H.4
Damber, J.E.5
Welen, K.6
-
57
-
-
84898923581
-
JAK-STAT3 and somatic cell reprogramming
-
Tang, Y.; Tian, X.C. JAK-STAT3 and somatic cell reprogramming. JAKSTAT 2013, 2, e24935.
-
(2013)
JAKSTAT
, vol.2
-
-
Tang, Y.1
Tian, X.C.2
-
58
-
-
84869204649
-
Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis
-
Tian, J.; Lee, S.O.; Liang, L.; Luo, J.; Huang, C.K.; Li, L.; Niu, Y.; Chang, C. Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis. J. Biol. Chem. 2012, 287, 39954-39966.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 39954-39966
-
-
Tian, J.1
Lee, S.O.2
Liang, L.3
Luo, J.4
Huang, C.K.5
Li, L.6
Niu, Y.7
Chang, C.8
-
59
-
-
84860642507
-
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration
-
Qin, J.; Liu, X.; Laffin, B.; Chen, X.; Choy, G.; Jeter, C.R.; Calhoun-Davis, T.; Li, H.; Palapattu, G.S.; Pang, S. et al. The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell 2012, 10, 556-569.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 556-569
-
-
Qin, J.1
Liu, X.2
Laffin, B.3
Chen, X.4
Choy, G.5
Jeter, C.R.6
Calhoun-Davis, T.7
Li, H.8
Palapattu, G.S.9
Pang, S.10
-
60
-
-
84894284619
-
Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling
-
doi:10.1158/0008-5472.CAN-13-0594
-
Schroeder, A.; Herrmann, A.; Cherryholmes, G.; Kowolik, C.; Buettner, R.; Pal, S.; Yu, H.; Mueller-Newen, G.; Jove, R. Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling. Cancer Res. 2013, doi:10.1158/0008-5472.CAN-13-0594.
-
(2013)
Cancer Res
-
-
Schroeder, A.1
Herrmann, A.2
Cherryholmes, G.3
Kowolik, C.4
Buettner, R.5
Pal, S.6
Yu, H.7
Mueller-Newen, G.8
Jove, R.9
-
61
-
-
39449098191
-
Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated STAT3
-
Hellsten, R.; Johansson, M.; Dahlman, A.; Dizeyi, N.; Sterner, O.; Bjartell, A. Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated STAT3. Prostate 2008, 68, 269-280.
-
(2008)
Prostate
, vol.68
, pp. 269-280
-
-
Hellsten, R.1
Johansson, M.2
Dahlman, A.3
Dizeyi, N.4
Sterner, O.5
Bjartell, A.6
-
62
-
-
84893511414
-
- subpopulations of breast cancer cells
-
- subpopulations of breast cancer cells. PLoS One 2013, 8, e82821.
-
(2013)
PLoS One
, vol.8
-
-
Lin, L.1
Hutzen, B.2
Lee, H.F.3
Peng, Z.4
Wang, W.5
Zhao, C.6
Lin, H.J.7
Sun, D.8
Li, P.K.9
Li, C.10
-
63
-
-
65549140597
-
Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach
-
Kawasaki, B.T.; Hurt, E.M.; Kalathur, M.; Duhagon, M.A.; Milner, J.A.; Kim, Y.S.; Farrar, W.L. Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach. Prostate 2009, 69, 827-837.
-
(2009)
Prostate
, vol.69
, pp. 827-837
-
-
Kawasaki, B.T.1
Hurt, E.M.2
Kalathur, M.3
Duhagon, M.A.4
Milner, J.A.5
Kim, Y.S.6
Farrar, W.L.7
-
64
-
-
84864465226
-
Clinical implications of cancer stem cell biology in hepatocellular carcinoma
-
Ji, J.; Wang, X.W. Clinical implications of cancer stem cell biology in hepatocellular carcinoma. Semin. Oncol. 2012, 39, 461-472.
-
(2012)
Semin. Oncol
, vol.39
, pp. 461-472
-
-
Ji, J.1
Wang, X.W.2
-
65
-
-
84873537569
-
Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
-
Kim, S.Y.; Kang, J.W.; Song, X.; Kim, B.K.; Yoo, Y.D.; Kwon, Y.T.; Lee, Y.J. Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells. Cell Signal. 2013, 25, 961-969.
-
(2013)
Cell Signal
, vol.25
, pp. 961-969
-
-
Kim, S.Y.1
Kang, J.W.2
Song, X.3
Kim, B.K.4
Yoo, Y.D.5
Kwon, Y.T.6
Lee, Y.J.7
-
66
-
-
84895756231
-
RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3
-
Islam, M.; Sharma, S.; Teknos, T.N. RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3. PLoS One 2014, 9, e88527.
-
(2014)
PLoS One
, vol.9
-
-
Islam, M.1
Sharma, S.2
Teknos, T.N.3
-
67
-
-
73649140983
-
Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: An initial study in GSC11 glioblastoma stem cells
-
Nilsson, C.L.; Dillon, R.; Devakumar, A.; Shi, S.D.; Greig, M.; Rogers, J.C.; Krastins, B.; Rosenblatt, M.; Kilmer, G.; Major, M. et al. Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: An initial study in GSC11 glioblastoma stem cells. J. Proteome Res. 2010, 9, 430-443.
-
(2010)
J. Proteome Res
, vol.9
, pp. 430-443
-
-
Nilsson, C.L.1
Dillon, R.2
Devakumar, A.3
Shi, S.D.4
Greig, M.5
Rogers, J.C.6
Krastins, B.7
Rosenblatt, M.8
Kilmer, G.9
Major, M.10
-
68
-
-
84882714320
-
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells
-
Kroon, P.; Berry, P.A.; Stower, M.J.; Rodrigues, G.; Mann, V.M.; Simms, M.; Bhasin, D.; Chettiar, S.; Li, C.; Li, P.K. et al. JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells. Cancer Res. 2013, 73, 5288-5298.
-
(2013)
Cancer Res
, vol.73
, pp. 5288-5298
-
-
Kroon, P.1
Berry, P.A.2
Stower, M.J.3
Rodrigues, G.4
Mann, V.M.5
Simms, M.6
Bhasin, D.7
Chettiar, S.8
Li, C.9
Li, P.K.10
-
69
-
-
84890295938
-
Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling
-
Qu, Y.; Oyan, A.M.; Liu, R.; Hua, Y.; Zhang, J.; Hovland, R.; Popa, M.; Liu, X.; Brokstad, K.A.; Simon, R. et al. Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling. Cancer Res. 2013, 73, 7090-7100.
-
(2013)
Cancer Res
, vol.73
, pp. 7090-7100
-
-
Qu, Y.1
Oyan, A.M.2
Liu, R.3
Hua, Y.4
Zhang, J.5
Hovland, R.6
Popa, M.7
Liu, X.8
Brokstad, K.A.9
Simon, R.10
-
70
-
-
84856645746
-
Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors
-
Salvatori, L.; Caporuscio, F.; Verdina, A.; Starace, G.; Crispi, S.; Nicotra, M.R.; Russo, A.; Calogero, R.A.; Morgante, E.; Natali, P.G. et al. Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors. PLoS One 2012, 7, e31467.
-
(2012)
PLoS One
, vol.7
-
-
Salvatori, L.1
Caporuscio, F.2
Verdina, A.3
Starace, G.4
Crispi, S.5
Nicotra, M.R.6
Russo, A.7
Calogero, R.A.8
Morgante, E.9
Natali, P.G.10
-
71
-
-
77957902732
-
Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells
-
Kong, D.; Banerjee, S.; Ahmad, A.; Li, Y.; Wang, Z.; Sethi, S.; Sarkar, F.H. Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One 2010, 5, e12445.
-
(2010)
PLoS One
, vol.5
-
-
Kong, D.1
Banerjee, S.2
Ahmad, A.3
Li, Y.4
Wang, Z.5
Sethi, S.6
Sarkar, F.H.7
-
72
-
-
84877855030
-
Hsp27 regulates epithelial mesenchymal transition, metastasis, and circulating tumor cells in prostate cancer
-
Shiota, M.; Bishop, J.L.; Nip, K.M.; Zardan, A.; Takeuchi, A.; Cordonnier, T.; Beraldi, E.; Bazov, J.; Fazli, L.; Chi, K. et al. Hsp27 regulates epithelial mesenchymal transition, metastasis, and circulating tumor cells in prostate cancer. Cancer Res. 2013, 73, 3109-3119.
-
(2013)
Cancer Res
, vol.73
, pp. 3109-3119
-
-
Shiota, M.1
Bishop, J.L.2
Nip, K.M.3
Zardan, A.4
Takeuchi, A.5
Cordonnier, T.6
Beraldi, E.7
Bazov, J.8
Fazli, L.9
Chi, K.10
-
73
-
-
84883366629
-
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
-
Izumi, K.; Fang, L.Y.; Mizokami, A.; Namiki, M.; Li, L.; Lin, W.J.; Chang, C. Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation. EMBO Mol. Med. 2013, 5, 1383-1401.
-
(2013)
EMBO Mol. Med
, vol.5
, pp. 1383-1401
-
-
Izumi, K.1
Fang, L.Y.2
Mizokami, A.3
Namiki, M.4
Li, L.5
Lin, W.J.6
Chang, C.7
-
74
-
-
84894231936
-
A ROS/STAT3/HIF-1alpha signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion
-
doi:10.1002/pros.22776
-
Cho, K.H.; Choi, M.J.; Jeong, K.J.; Kim, J.J.; Hwang, M.H.; Shin, S.C.; Park, C.G.; Lee, H.Y. A ROS/STAT3/HIF-1alpha signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion. Prostate 2014, doi:10.1002/pros.22776.
-
(2014)
Prostate
-
-
Cho, K.H.1
Choi, M.J.2
Jeong, K.J.3
Kim, J.J.4
Hwang, M.H.5
Shin, S.C.6
Park, C.G.7
Lee, H.Y.8
-
75
-
-
84878960353
-
STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion
-
Cho, K.H.; Jeong, K.J.; Shin, S.C.; Kang, J.; Park, C.G.; Lee, H.Y. STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion. Cancer Lett. 2013, 336, 167-173.
-
(2013)
Cancer Lett
, vol.336
, pp. 167-173
-
-
Cho, K.H.1
Jeong, K.J.2
Shin, S.C.3
Kang, J.4
Park, C.G.5
Lee, H.Y.6
-
76
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
77
-
-
0033119833
-
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
-
Grunstein, J.; Roberts, W.G.; Mathieu-Costello, O.; Hanahan, D.; Johnson, R.S. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res. 1999, 59, 1592-1598.
-
(1999)
Cancer Res
, vol.59
, pp. 1592-1598
-
-
Grunstein, J.1
Roberts, W.G.2
Mathieu-Costello, O.3
Hanahan, D.4
Johnson, R.S.5
-
78
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate, K.H.; Breier, G.; Weich, H.A.; Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992, 359, 845-848.
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
79
-
-
39549102220
-
STAT3: A critical transcription activator in angiogenesis
-
Chen, Z.; Han, Z.C. STAT3: A critical transcription activator in angiogenesis. Med. Res. Rev. 2008, 28, 185-200.
-
(2008)
Med. Res. Rev
, vol.28
, pp. 185-200
-
-
Chen, Z.1
Han, Z.C.2
-
80
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
Xu, Q.; Briggs, J.; Park, S.; Niu, G.; Kortylewski, M.; Zhang, S.; Gritsko, T.; Turkson, J.; Kay, H.; Semenza, G.L. et al. Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 2005, 24, 5552-5560.
-
(2005)
Oncogene
, vol.24
, pp. 5552-5560
-
-
Xu, Q.1
Briggs, J.2
Park, S.3
Niu, G.4
Kortylewski, M.5
Zhang, S.6
Gritsko, T.7
Turkson, J.8
Kay, H.9
Semenza, G.L.10
-
81
-
-
0037461934
-
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
-
Wei, D.; Le, X.; Zheng, L.; Wang, L.; Frey, J.A.; Gao, A.C.; Peng, Z.; Huang, S.; Xiong, H.Q.; Abbruzzese, J.L. et al. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene 2003, 22, 319-329.
-
(2003)
Oncogene
, vol.22
, pp. 319-329
-
-
Wei, D.1
Le, X.2
Zheng, L.3
Wang, L.4
Frey, J.A.5
Gao, A.C.6
Peng, Z.7
Huang, S.8
Xiong, H.Q.9
Abbruzzese, J.L.10
-
82
-
-
85047695527
-
Constitutive STAT3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu, G.; Wright, K.L.; Huang, M.; Song, L.; Haura, E.; Turkson, J.; Zhang, S.; Wang, T.; Sinibaldi, D.; Coppola, D. et al. Constitutive STAT3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002, 21, 2000-2008.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
Song, L.4
Haura, E.5
Turkson, J.6
Zhang, S.7
Wang, T.8
Sinibaldi, D.9
Coppola, D.10
-
83
-
-
84873041658
-
Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site
-
Eisermann, K.; Broderick, C.J.; Bazarov, A.; Moazam, M.M.; Fraizer, G.C. Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site. Mol. Cancer 2013, 12, e7.
-
(2013)
Mol. Cancer
, vol.12
-
-
Eisermann, K.1
Broderick, C.J.2
Bazarov, A.3
Moazam, M.M.4
Fraizer, G.C.5
-
84
-
-
79960890780
-
JAK2/STAT3 signaling pathway activation mediates tumor angiogenesis by upregulation of VEGF and bFGF in non-small-cell lung cancer
-
Zhao, M.; Gao, F.H.; Wang, J.Y.; Liu, F.; Yuan, H.H.; Zhang, W.Y.; Jiang, B. JAK2/STAT3 signaling pathway activation mediates tumor angiogenesis by upregulation of VEGF and bFGF in non-small-cell lung cancer. Lung Cancer 2011, 73, 366-374.
-
(2011)
Lung Cancer
, vol.73
, pp. 366-374
-
-
Zhao, M.1
Gao, F.H.2
Wang, J.Y.3
Liu, F.4
Yuan, H.H.5
Zhang, W.Y.6
Jiang, B.7
-
85
-
-
55849107422
-
Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice
-
Kujawski, M.; Kortylewski, M.; Lee, H.; Herrmann, A.; Kay, H.; Yu, H. Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. J. Clin. Invest. 2008, 118, 3367-3377.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3367-3377
-
-
Kujawski, M.1
Kortylewski, M.2
Lee, H.3
Herrmann, A.4
Kay, H.5
Yu, H.6
-
86
-
-
84878339255
-
Delivery of the co-expression plasmid pEndo-Si-STAT3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment
-
Li, X.; Li, Y.; Wang, B.; Ji, K.; Liang, Z.; Guo, B.; Hu, J.; Yin, D.; Du, Y.; Kopecko, D.J. et al. Delivery of the co-expression plasmid pEndo-Si-STAT3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment. J. Cancer Res. Clin. Oncol. 2013, 139, 971-980.
-
(2013)
J. Cancer Res. Clin. Oncol
, vol.139
, pp. 971-980
-
-
Li, X.1
Li, Y.2
Wang, B.3
Ji, K.4
Liang, Z.5
Guo, B.6
Hu, J.7
Yin, D.8
Du, Y.9
Kopecko, D.J.10
-
87
-
-
55549090712
-
Hepatitis C virus core protein augments androgen receptor-mediated signaling
-
Kanda, T.; Steele, R.; Ray, R.; Ray, R.B. Hepatitis C virus core protein augments androgen receptor-mediated signaling. J. Virol. 2008, 82, 11066-11072.
-
(2008)
J. Virol
, vol.82
, pp. 11066-11072
-
-
Kanda, T.1
Steele, R.2
Ray, R.3
Ray, R.B.4
-
88
-
-
84878142242
-
Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model
-
Hafeez, B.B.; Zhong, W.; Fischer, J.W.; Mustafa, A.; Shi, X.; Meske, L.; Hong, H.; Cai, W.; Havighurst, T.; Kim, K. et al. Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model. Mol. Oncol. 2013, 7, 428-439.
-
(2013)
Mol. Oncol
, vol.7
, pp. 428-439
-
-
Hafeez, B.B.1
Zhong, W.2
Fischer, J.W.3
Mustafa, A.4
Shi, X.5
Meske, L.6
Hong, H.7
Cai, W.8
Havighurst, T.9
Kim, K.10
-
89
-
-
84870326497
-
Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCepsilon, Stat3 and neuroendocrine markers
-
Hafeez, B.B.; Zhong, W.; Mustafa, A.; Fischer, J.W.; Witkowsky, O.; Verma, A.K. Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCepsilon, Stat3 and neuroendocrine markers. Carcinogenesis 2012, 33, 2586-2592.
-
(2012)
Carcinogenesis
, vol.33
, pp. 2586-2592
-
-
Hafeez, B.B.1
Zhong, W.2
Mustafa, A.3
Fischer, J.W.4
Witkowsky, O.5
Verma, A.K.6
-
90
-
-
55349147671
-
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer
-
Aziz, M.H.; Dreckschmidt, N.E.; Verma, A.K. Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer. Cancer Res. 2008, 68, 9024-9032.
-
(2008)
Cancer Res
, vol.68
, pp. 9024-9032
-
-
Aziz, M.H.1
Dreckschmidt, N.E.2
Verma, A.K.3
-
91
-
-
79959606207
-
Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells
-
Shin, J.; Lee, H.J.; Jung, D.B.; Jung, J.H.; Lee, E.O.; Lee, S.G.; Shim, B.S.; Choi, S.H.; Ko, S.G.; Ahn, K.S. et al. Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells. PLoS One 2011, 6, e21492.
-
(2011)
PLoS One
, vol.6
-
-
Shin, J.1
Lee, H.J.2
Jung, D.B.3
Jung, J.H.4
Lee, E.O.5
Lee, S.G.6
Shim, B.S.7
Choi, S.H.8
Ko, S.G.9
Ahn, K.S.10
-
92
-
-
80052962987
-
Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell
-
Zhang, X.; Song, Y.; Wu, Y.; Dong, Y.; Lai, L.; Zhang, J.; Lu, B.; Dai, F.; He, L.; Liu, M. et al. Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell. Int. J. Cancer 2011, 129, 2502-2511.
-
(2011)
Int. J. Cancer
, vol.129
, pp. 2502-2511
-
-
Zhang, X.1
Song, Y.2
Wu, Y.3
Dong, Y.4
Lai, L.5
Zhang, J.6
Lu, B.7
Dai, F.8
He, L.9
Liu, M.10
-
93
-
-
80054057846
-
Combined treatment targeting HIF-1α and STAT3 is a potent strategy for prostate cancer therapy
-
Reddy, K.R.; Guan, Y.; Qin, G.; Zhou, Z.; Jing, N. Combined treatment targeting HIF-1α and STAT3 is a potent strategy for prostate cancer therapy. Prostate 2011, 71, 1796-1809.
-
(2011)
Prostate
, vol.71
, pp. 1796-1809
-
-
Reddy, K.R.1
Guan, Y.2
Qin, G.3
Zhou, Z.4
Jing, N.5
-
94
-
-
84864389212
-
A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells
-
Rathinavelu, A.; Narasimhan, M.; Muthumani, P. A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells. J. Cell. Mol. Med. 2012, 16, 1750-1757.
-
(2012)
J. Cell. Mol. Med
, vol.16
, pp. 1750-1757
-
-
Rathinavelu, A.1
Narasimhan, M.2
Muthumani, P.3
-
95
-
-
84869223265
-
The reactive stroma microenvironment and prostate cancer progression
-
Barron, D.A.; Rowley, D.R. The reactive stroma microenvironment and prostate cancer progression. Endocr. Relat. Cancer 2012, 19, R187-R204.
-
(2012)
Endocr. Relat. Cancer
, vol.19
-
-
Barron, D.A.1
Rowley, D.R.2
-
96
-
-
84886383331
-
Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment
-
Brennen, W.N.; Denmeade, S.R.; Isaacs, J.T. Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment. Endocr. Relat. Cancer 2013, 20, R269-R290.
-
(2013)
Endocr. Relat. Cancer
, vol.20
-
-
Brennen, W.N.1
Denmeade, S.R.2
Isaacs, J.T.3
-
97
-
-
84892908353
-
FGFR1-WNT-TGF-beta Signaling in prostate cancer mouse models recapitulates human reactive stroma
-
Carstens, J.L.; Shahi, P.; van Tsang, S.; Smith, B.; Creighton, C.J.; Zhang, Y.; Seamans, A.; Seethammagari, M.; Vedula, I.; Levitt, J.M. et al. FGFR1-WNT-TGF-beta Signaling in prostate cancer mouse models recapitulates human reactive stroma. Cancer Res. 2014, 74, 609-620.
-
(2014)
Cancer Res
, vol.74
, pp. 609-620
-
-
Carstens, J.L.1
Shahi, P.2
van Tsang, S.3
Smith, B.4
Creighton, C.J.5
Zhang, Y.6
Seamans, A.7
Seethammagari, M.8
Vedula, I.9
Levitt, J.M.10
-
98
-
-
58149215849
-
Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis
-
Li, X.; Placencio, V.; Iturregui, J.M.; Uwamariya, C.; Sharif-Afshar, A.R.; Koyama, T.; Hayward, S.W.; Bhowmick, N.A. Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis. Oncogene 2008, 27, 7118-7130.
-
(2008)
Oncogene
, vol.27
, pp. 7118-7130
-
-
Li, X.1
Placencio, V.2
Iturregui, J.M.3
Uwamariya, C.4
Sharif-Afshar, A.R.5
Koyama, T.6
Hayward, S.W.7
Bhowmick, N.A.8
-
99
-
-
84895926497
-
Extracellular Hsp90 mediates an NF-κB dependent inflammatory stromal program: Implications for the prostate tumor microenvironment
-
Bohonowych, J.; Hance, M.; Nolan, K.; Defee, M.; Parsons, C.; Isaacs, J. Extracellular Hsp90 mediates an NF-κB dependent inflammatory stromal program: Implications for the prostate tumor microenvironment. Prostate 2014, 74, 395-407.
-
(2014)
Prostate
, vol.74
, pp. 395-407
-
-
Bohonowych, J.1
Hance, M.2
Nolan, K.3
Defee, M.4
Parsons, C.5
Isaacs, J.6
-
100
-
-
84861882582
-
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells
-
Tsuyada, A.; Chow, A.; Wu, J.; Somlo, G.; Chu, P.; Loera, S.; Luu, T.; Li, A.X.; Wu, X.; Ye, W. et al. CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res. 2012, 72, 2768-2779.
-
(2012)
Cancer Res
, vol.72
, pp. 2768-2779
-
-
Tsuyada, A.1
Chow, A.2
Wu, J.3
Somlo, G.4
Chu, P.5
Loera, S.6
Luu, T.7
Li, A.X.8
Wu, X.9
Ye, W.10
-
101
-
-
84898912407
-
A CCL2/ROS autoregulation loop is critical for cancer associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma
-
doi: 10.1093/carcin/bgu046
-
Li, X.; Xu, Q.; Wu, Y.; Li, J.; Tang, D.; Han, L.; Fan, Q. A CCL2/ROS autoregulation loop is critical for cancer associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma. Carcinogenesis 2014, doi: 10.1093/carcin/bgu046.
-
(2014)
Carcinogenesis
-
-
Li, X.1
Xu, Q.2
Wu, Y.3
Li, J.4
Tang, D.5
Han, L.6
Fan, Q.7
-
102
-
-
84885648162
-
Hypoxia preconditioning of mesenchymal stromal cells enhances PC3 cell lymphatic metastasis accompanied by VEGFR-3/CCR7 activation
-
Huang, X.; Su, K.; Zhou, L.; Shen, G.; Dong, Q.; Lou, Y.; Zheng, S. Hypoxia preconditioning of mesenchymal stromal cells enhances PC3 cell lymphatic metastasis accompanied by VEGFR-3/CCR7 activation. J. Cell. Biochem. 2013, 114, 2834-2841.
-
(2013)
J. Cell. Biochem
, vol.114
, pp. 2834-2841
-
-
Huang, X.1
Su, K.2
Zhou, L.3
Shen, G.4
Dong, Q.5
Lou, Y.6
Zheng, S.7
-
103
-
-
84897556892
-
TGF-beta in CAF-mediated tumor growth and metastasis
-
doi:10.1016/j.semcancer.2013.12.008
-
Calon, A.; Tauriello, D.V.; Batlle, E. TGF-beta in CAF-mediated tumor growth and metastasis. Semin. Cancer Biol. 2014, doi:10.1016/j.semcancer.2013.12.008.
-
(2014)
Semin. Cancer Biol
-
-
Calon, A.1
Tauriello, D.V.2
Batlle, E.3
-
104
-
-
77949347731
-
Pathogenesis of osteoblastic bone metastases from prostate cancer
-
Ibrahim, T.; Flamini, E.; Mercatali, L.; Sacanna, E.; Serra, P.; Amadori, D. Pathogenesis of osteoblastic bone metastases from prostate cancer. Cancer 2010, 116, 1406-1418.
-
(2010)
Cancer
, vol.116
, pp. 1406-1418
-
-
Ibrahim, T.1
Flamini, E.2
Mercatali, L.3
Sacanna, E.4
Serra, P.5
Amadori, D.6
-
105
-
-
30944436527
-
Mechanisms of disease: Roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis
-
Blair, J.M.; Zhou, H.; Seibel, M.J.; Dunstan, C.R. Mechanisms of disease: Roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis. Nat. Clin. Pract. Oncol. 2006, 3, 41-49.
-
(2006)
Nat. Clin. Pract. Oncol
, vol.3
, pp. 41-49
-
-
Blair, J.M.1
Zhou, H.2
Seibel, M.J.3
Dunstan, C.R.4
-
106
-
-
51049121618
-
RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis
-
Miller, R.E.; Roudier, M.; Jones, J.; Armstrong, A.; Canon, J.; Dougall, W.C. RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. Mol. Cancer Ther. 2008, 7, 2160-2169.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 2160-2169
-
-
Miller, R.E.1
Roudier, M.2
Jones, J.3
Armstrong, A.4
Canon, J.5
Dougall, W.C.6
-
107
-
-
37449004858
-
RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes
-
Armstrong, A.P.; Miller, R.E.; Jones, J.C.; Zhang, J.; Keller, E.T.; Dougall, W.C. RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes. Prostate 2008, 68, 92-104.
-
(2008)
Prostate
, vol.68
, pp. 92-104
-
-
Armstrong, A.P.1
Miller, R.E.2
Jones, J.C.3
Zhang, J.4
Keller, E.T.5
Dougall, W.C.6
-
108
-
-
59149087622
-
Receptor activator of nuclear factor-kappa B ligand (RANKL) stimulates bone-associated tumors through functional RANK expressed on bone-associated cancer cells?
-
Mori, K.; Ando, K.; Heymann, D.; Redini, F. Receptor activator of nuclear factor-kappa B ligand (RANKL) stimulates bone-associated tumors through functional RANK expressed on bone-associated cancer cells? Histol. Histopathol. 2009, 24, 235-242.
-
(2009)
Histol. Histopathol
, vol.24
, pp. 235-242
-
-
Mori, K.1
Ando, K.2
Heymann, D.3
Redini, F.4
-
109
-
-
33847729474
-
DU145 human prostate cancer cells express functional receptor activator of NFkappaB: New insights in the prostate cancer bone metastasis process
-
Mori, K.; Le Goff, B.; Charrier, C.; Battaglia, S.; Heymann, D.; Redini, F. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: New insights in the prostate cancer bone metastasis process. Bone 2007, 40, 981-990.
-
(2007)
Bone
, vol.40
, pp. 981-990
-
-
Mori, K.1
Le Goff, B.2
Charrier, C.3
Battaglia, S.4
Heymann, D.5
Redini, F.6
-
110
-
-
74249112769
-
Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism
-
Schulze, J.; Albers, J.; Baranowsky, A.; Keller, J.; Spiro, A.; Streichert, T.; Zustin, J.; Amling, M.; Schinke, T. Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism. Bone 2010, 46, 524-533.
-
(2010)
Bone
, vol.46
, pp. 524-533
-
-
Schulze, J.1
Albers, J.2
Baranowsky, A.3
Keller, J.4
Spiro, A.5
Streichert, T.6
Zustin, J.7
Amling, M.8
Schinke, T.9
-
111
-
-
48649094682
-
Histopathological assessment of prostate cancer bone osteoblastic metastases
-
Roudier, M.P.; Morrissey, C.; True, L.D.; Higano, C.S.; Vessella, R.L.; Ott, S.M. Histopathological assessment of prostate cancer bone osteoblastic metastases. J. Urol. 2008, 180, 1154-1160.
-
(2008)
J. Urol
, vol.180
, pp. 1154-1160
-
-
Roudier, M.P.1
Morrissey, C.2
True, L.D.3
Higano, C.S.4
Vessella, R.L.5
Ott, S.M.6
-
112
-
-
84863338444
-
Disseminated prostate cancer cells can instruct hematopoietic stem and progenitor cells to regulate bone phenotype
-
Joseph, J.; Shiozawa, Y.; Jung, Y.; Kim, J.K.; Pedersen, E.; Mishra, A.; Zalucha, J.L.; Wang, J.; Keller, E.T.; Pienta, K.J. et al. Disseminated prostate cancer cells can instruct hematopoietic stem and progenitor cells to regulate bone phenotype. Mol. Cancer Res. 2012, 10, 282-292.
-
(2012)
Mol. Cancer Res
, vol.10
, pp. 282-292
-
-
Joseph, J.1
Shiozawa, Y.2
Jung, Y.3
Kim, J.K.4
Pedersen, E.5
Mishra, A.6
Zalucha, J.L.7
Wang, J.8
Keller, E.T.9
Pienta, K.J.10
-
113
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
114
-
-
84891824280
-
STAT3 activation: A key factor in tumor immunoescape
-
Rebe, C.; Vegran, F.; Berger, H.; Ghiringhelli, F. STAT3 activation: A key factor in tumor immunoescape. JAKSTAT 2013, 2, e23010.
-
(2013)
JAKSTAT
, vol.2
-
-
Rebe, C.1
Vegran, F.2
Berger, H.3
Ghiringhelli, F.4
-
115
-
-
84874669956
-
HVEM: An unusual TNF receptor family member important for mucosal innate immune responses to microbes
-
Shui, J.W.; Kronenberg, M. HVEM: An unusual TNF receptor family member important for mucosal innate immune responses to microbes. Gut Microbes 2013, 4, 146-151.
-
(2013)
Gut Microbes
, vol.4
, pp. 146-151
-
-
Shui, J.W.1
Kronenberg, M.2
-
116
-
-
84862111685
-
IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells
-
Matta, B.M.; Raimondi, G.; Rosborough, B.R.; Sumpter, T.L.; Thomson, A.W. IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells. J. Immunol. 2012, 188, 5227-5237.
-
(2012)
J. Immunol
, vol.188
, pp. 5227-5237
-
-
Matta, B.M.1
Raimondi, G.2
Rosborough, B.R.3
Sumpter, T.L.4
Thomson, A.W.5
-
117
-
-
78851471039
-
PD-L1 expression on tolerogenic APCs is controlled by STAT-3
-
Wolfle, S.J.; Strebovsky, J.; Bartz, H.; Sahr, A.; Arnold, C.; Kaiser, C.; Dalpke, A.H.; Heeg, K. PD-L1 expression on tolerogenic APCs is controlled by STAT-3. Eur. J. Immunol. 2011, 41, 413-424.
-
(2011)
Eur. J. Immunol
, vol.41
, pp. 413-424
-
-
Wolfle, S.J.1
Strebovsky, J.2
Bartz, H.3
Sahr, A.4
Arnold, C.5
Kaiser, C.6
Dalpke, A.H.7
Heeg, K.8
-
118
-
-
84873336707
-
The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition
-
Jiang, X.; Zhou, J.; Giobbie-Hurder, A.; Wargo, J.; Hodi, F.S. The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition. Clin. Cancer Res. 2013, 19, 598-609.
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 598-609
-
-
Jiang, X.1
Zhou, J.2
Giobbie-Hurder, A.3
Wargo, J.4
Hodi, F.S.5
-
119
-
-
84856403025
-
Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models
-
Shen, L.; Ciesielski, M.; Ramakrishnan, S.; Miles, K.M.; Ellis, L.; Sotomayor, P.; Shrikant, P.; Fenstermaker, R.; Pili, R. Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models. PLoS One 2012, 7, e30815.
-
(2012)
PLoS One
, vol.7
-
-
Shen, L.1
Ciesielski, M.2
Ramakrishnan, S.3
Miles, K.M.4
Ellis, L.5
Sotomayor, P.6
Shrikant, P.7
Fenstermaker, R.8
Pili, R.9
-
120
-
-
84880697448
-
The role of IL-6 in the radiation response of prostate cancer
-
Wu, C.T.; Chen, M.F.; Chen, W.C.; Hsieh, C.C. The role of IL-6 in the radiation response of prostate cancer. Radiat. Oncol. 2013, 8, e159.
-
(2013)
Radiat. Oncol
, vol.8
-
-
Wu, C.T.1
Chen, M.F.2
Chen, W.C.3
Hsieh, C.C.4
-
121
-
-
84884752495
-
Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling
-
Fang, L.Y.; Izumi, K.; Lai, K.P.; Liang, L.; Li, L.; Miyamoto, H.; Lin, W.J.; Chang, C. Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling. Cancer Res. 2013, 73, 5633-5646.
-
(2013)
Cancer Res
, vol.73
, pp. 5633-5646
-
-
Fang, L.Y.1
Izumi, K.2
Lai, K.P.3
Liang, L.4
Li, L.5
Miyamoto, H.6
Lin, W.J.7
Chang, C.8
-
122
-
-
84882653809
-
Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
-
Lin, T.H.; Izumi, K.; Lee, S.O.; Lin, W.J.; Yeh, S.; Chang, C. Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling. Cell. Death Dis. 2013, 4, e764.
-
(2013)
Cell. Death Dis
, vol.4
-
-
Lin, T.H.1
Izumi, K.2
Lee, S.O.3
Lin, W.J.4
Yeh, S.5
Chang, C.6
-
123
-
-
77949379050
-
B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
-
Ammirante, M.; Luo, J.L.; Grivennikov, S.; Nedospasov, S.; Karin, M. B-cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 2010, 464, 302-305.
-
(2010)
Nature
, vol.464
, pp. 302-305
-
-
Ammirante, M.1
Luo, J.L.2
Grivennikov, S.3
Nedospasov, S.4
Karin, M.5
-
124
-
-
0035875931
-
Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice
-
Smith, P.C.; Keller, E.T. Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice. Prostate 2001, 48, 47-53.
-
(2001)
Prostate
, vol.48
, pp. 47-53
-
-
Smith, P.C.1
Keller, E.T.2
-
125
-
-
33645514605
-
Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice
-
Wallner, L.; Dai, J.; Escara-Wilke, J.; Zhang, J.; Yao, Z.; Lu, Y.; Trikha, M.; Nemeth, J.A.; Zaki, M.H.; Keller, E.T. Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res. 2006, 66, 3087-3095.
-
(2006)
Cancer Res
, vol.66
, pp. 3087-3095
-
-
Wallner, L.1
Dai, J.2
Escara-Wilke, J.3
Zhang, J.4
Yao, Z.5
Lu, Y.6
Trikha, M.7
Nemeth, J.A.8
Zaki, M.H.9
Keller, E.T.10
-
126
-
-
84879099298
-
A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer
-
Hudes, G.; Tagawa, S.T.; Whang, Y.E.; Qi, M.; Qin, X.; Puchalski, T.A.; Reddy, M.; Cornfeld, M.; Eisenberger, M. A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer. Invest. New Drugs 2013, 31, 669-676.
-
(2013)
Invest. New Drugs
, vol.31
, pp. 669-676
-
-
Hudes, G.1
Tagawa, S.T.2
Whang, Y.E.3
Qi, M.4
Qin, X.5
Puchalski, T.A.6
Reddy, M.7
Cornfeld, M.8
Eisenberger, M.9
-
127
-
-
83255176682
-
Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer
-
Fizazi, K.; de Bono, J.S.; Flechon, A.; Heidenreich, A.; Voog, E.; Davis, N.B.; Qi, M.; Bandekar, R.; Vermeulen, J.T.; Cornfeld, M. et al. Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer. Eur. J. Cancer 2012, 48, 85-93.
-
(2012)
Eur. J. Cancer
, vol.48
, pp. 85-93
-
-
Fizazi, K.1
de Bono, J.S.2
Flechon, A.3
Heidenreich, A.4
Voog, E.5
Davis, N.B.6
Qi, M.7
Bandekar, R.8
Vermeulen, J.T.9
Cornfeld, M.10
-
128
-
-
41949104346
-
Design and End Points of Clinical Trials For Patients With Progressive Prostate Cancer and Castrate Levels of Testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
-
Scher, H.I.; Halabi, S.; Tannock, I.; Morris, M.; Sternberg, C.N.; Carducci, M.A.; Eisenberger, M.A.; Higano, C.G.; Bubley, J.; Dreicer, R. et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group. J. Clin. Oncol. 2008, 26, 1148-1159.
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
Morris, M.4
Sternberg, C.N.5
Carducci, M.A.6
Eisenberger, M.A.7
Higano, C.G.8
Bubley, J.9
Dreicer, R.10
-
129
-
-
84876420606
-
The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer
-
Ischia, J.; Saad, F.; Gleave, M. The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer. Curr. Opin. Urol. 2013, 23, 194-200.
-
(2013)
Curr. Opin. Urol
, vol.23
, pp. 194-200
-
-
Ischia, J.1
Saad, F.2
Gleave, M.3
-
130
-
-
28244456529
-
Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis
-
Rocchi, P.; Beraldi, E.; Ettinger, S.; Fazli, L.; Vessella, R.L.; Nelson, C.; Gleave, M. Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis. Cancer Res. 2005, 65, 11083-11093.
-
(2005)
Cancer Res
, vol.65
, pp. 11083-11093
-
-
Rocchi, P.1
Beraldi, E.2
Ettinger, S.3
Fazli, L.4
Vessella, R.L.5
Nelson, C.6
Gleave, M.7
-
131
-
-
0036781479
-
Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines
-
Nakamura, K.; Yasunaga, Y.; Segawa, T.; Ko, D.; Moul, J.W.; Srivastava, S.; Rhim, J.S. Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines. Int. J. Oncol. 2002, 21, 825-830.
-
(2002)
Int. J. Oncol
, vol.21
, pp. 825-830
-
-
Nakamura, K.1
Yasunaga, Y.2
Segawa, T.3
Ko, D.4
Moul, J.W.5
Srivastava, S.6
Rhim, J.S.7
-
132
-
-
84880487998
-
Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor
-
Guo, H.; Xu, Y.M.; Ye, Z.Q.; Yu, J.H.; Hu, X.Y. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie 2013, 68, 431-434.
-
(2013)
Pharmazie
, vol.68
, pp. 431-434
-
-
Guo, H.1
Xu, Y.M.2
Ye, Z.Q.3
Yu, J.H.4
Hu, X.Y.5
-
133
-
-
84861476075
-
Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway
-
Yang, C.L.; Liu, Y.Y.; Ma, Y.G.; Xue, Y.X.; Liu, D.G.; Ren, Y.; Liu, X.B.; Li, Y.; Li, Z. Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway. PLoS One 2012, 7, e37960.
-
(2012)
PLoS One
, vol.7
-
-
Yang, C.L.1
Liu, Y.Y.2
Ma, Y.G.3
Xue, Y.X.4
Liu, D.G.5
Ren, Y.6
Liu, X.B.7
Li, Y.8
Li, Z.9
-
134
-
-
28044460494
-
Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak
-
Singh, S.V.; Zeng, Y.; Xiao, D.; Vogel, V.G.; Nelson, J.B.; Dhir, R.; Tripathi, Y.B. Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak. Mol. Cancer Ther. 2005, 4, 1747-1754.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 1747-1754
-
-
Singh, S.V.1
Zeng, Y.2
Xiao, D.3
Vogel, V.G.4
Nelson, J.B.5
Dhir, R.6
Tripathi, Y.B.7
-
135
-
-
0033529704
-
STAT3 as an oncogene
-
Bromberg, J.F.; Wrzeszczynska, M.H.; Devgan, G.; Zhao, Y.; Pestell, R.G.; Albanese, C.; Darnell, J.E., Jr. STAT3 as an oncogene. Cell 1999, 98, 295-303.
-
(1999)
Cell
, vol.98
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell Jr., J.E.7
-
136
-
-
33750632572
-
+ anaplastic large-cell lymphoma
-
+ anaplastic large-cell lymphoma. Blood 2006, 108, 2796-2803.
-
(2006)
Blood
, vol.108
, pp. 2796-2803
-
-
Han, Y.1
Amin, H.M.2
Franko, B.3
Frantz, C.4
Shi, X.5
Lai, R.6
-
137
-
-
78149460936
-
Effect of capsaicin on prostate cancer cells
-
Diaz-Laviada, I. Effect of capsaicin on prostate cancer cells. Future Oncol. 2010, 6, 1545-1550.
-
(2010)
Future Oncol
, vol.6
, pp. 1545-1550
-
-
Diaz-Laviada, I.1
-
138
-
-
63349085786
-
Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress
-
Lee, H.K.; Seo, I.A.; Shin, Y.K.; Park, J.W.; Suh, D.J.; Park, H.T. Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress. Biochem. Biophys. Res. Commun. 2009, 382, 445-450.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.382
, pp. 445-450
-
-
Lee, H.K.1
Seo, I.A.2
Shin, Y.K.3
Park, J.W.4
Suh, D.J.5
Park, H.T.6
-
139
-
-
84874610297
-
Celastrol suppresses tumor cell growth through targeting an AR-ERG-NF-κB pathway in TMPRSS2/ERG fusion gene expressing prostate cancer
-
Shao, L.; Zhou, Z.; Cai, Y.; Castro, P.; Dakhov, O.; Shi, P.; Bai, Y.; Ji, H.; Shen, W.; Wang, J. Celastrol suppresses tumor cell growth through targeting an AR-ERG-NF-κB pathway in TMPRSS2/ERG fusion gene expressing prostate cancer. PLoS One 2013, 8, e58391.
-
(2013)
PLoS One
, vol.8
-
-
Shao, L.1
Zhou, Z.2
Cai, Y.3
Castro, P.4
Dakhov, O.5
Shi, P.6
Bai, Y.7
Ji, H.8
Shen, W.9
Wang, J.10
-
140
-
-
84864835881
-
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo
-
Rajendran, P.; Li, F.; Shanmugam, M.K.; Kannaiyan, R.; Goh, J.N.; Wong, K.F.; Wang, W.; Khin, E.; Tergaonkar, V.; Kumar, A.P. et al. Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo. Cancer Prev. Res. 2012, 5, 631-643.
-
(2012)
Cancer Prev. Res
, vol.5
, pp. 631-643
-
-
Rajendran, P.1
Li, F.2
Shanmugam, M.K.3
Kannaiyan, R.4
Goh, J.N.5
Wong, K.F.6
Wang, W.7
Khin, E.8
Tergaonkar, V.9
Kumar, A.P.10
-
141
-
-
84885856206
-
Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells
-
Sanderson, J.T.; Clabault, H.; Patton, C.; Lassalle-Claux, G.; Jean-Francois, J.; Pare, A.F.; Hebert, M.J.; Surette, M.E.; Touaibia, M. Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells. Bioorg. Med. Chem. 2013, 21, 7182-7193.
-
(2013)
Bioorg. Med. Chem
, vol.21
, pp. 7182-7193
-
-
Sanderson, J.T.1
Clabault, H.2
Patton, C.3
Lassalle-Claux, G.4
Jean-Francois, J.5
Pare, A.F.6
Hebert, M.J.7
Surette, M.E.8
Touaibia, M.9
-
142
-
-
84878530487
-
The anticancer mechanism of caffeic acid phenethyl ester (CAPE): Review of melanomas, lung and prostate cancers
-
Ozturk, G.; Ginis, Z.; Akyol, S.; Erden, G.; Gurel, A.; Akyol, O. The anticancer mechanism of caffeic acid phenethyl ester (CAPE): Review of melanomas, lung and prostate cancers. Eur. Rev. Med. Pharmacol. Sci. 2012, 16, 2064-2068.
-
(2012)
Eur. Rev. Med. Pharmacol. Sci
, vol.16
, pp. 2064-2068
-
-
Ozturk, G.1
Ginis, Z.2
Akyol, S.3
Erden, G.4
Gurel, A.5
Akyol, O.6
-
143
-
-
84861553261
-
Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway
-
Lin, C.L.; Chen, R.F.; Chen, J.Y.; Chu, Y.C.; Wang, H.M.; Chou, H.L.; Chang, W.C.; Fong, Y.; Chang, W.T.; Wu, C.Y. et al. Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway. Int. J. Mol. Sci. 2012, 13, 6236-6245.
-
(2012)
Int. J. Mol. Sci
, vol.13
, pp. 6236-6245
-
-
Lin, C.L.1
Chen, R.F.2
Chen, J.Y.3
Chu, Y.C.4
Wang, H.M.5
Chou, H.L.6
Chang, W.C.7
Fong, Y.8
Chang, W.T.9
Wu, C.Y.10
-
144
-
-
0030598398
-
Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells
-
Duncan, K.L.; Duncan, M.D.; Alley, M.C.; Sausville, E.A. Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells. Biochem. Pharmacol. 1996, 52, 1553-1560.
-
(1996)
Biochem. Pharmacol
, vol.52
, pp. 1553-1560
-
-
Duncan, K.L.1
Duncan, M.D.2
Alley, M.C.3
Sausville, E.A.4
-
145
-
-
77953807862
-
Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin
-
Liu, T.; Peng, H.; Zhang, M.; Deng, Y.; Wu, Z. Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin. Eur. J. Pharmacol. 2010, 641, 15-22.
-
(2010)
Eur. J. Pharmacol
, vol.641
, pp. 15-22
-
-
Liu, T.1
Peng, H.2
Zhang, M.3
Deng, Y.4
Wu, Z.5
-
146
-
-
84855350566
-
Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells
-
Xu, D.; Lin, T.H.; Li, S.; Da, J.; Wen, X.Q.; Ding, J.; Chang, C.; Yeh, S. Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells. Cancer Lett. 2012, 316, 11-22.
-
(2012)
Cancer Lett
, vol.316
, pp. 11-22
-
-
Xu, D.1
Lin, T.H.2
Li, S.3
Da, J.4
Wen, X.Q.5
Ding, J.6
Chang, C.7
Yeh, S.8
-
147
-
-
58249119435
-
Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells
-
Shin, D.S.; Kim, H.N.; Shin, K.D.; Yoon, Y.J.; Kim, S.J.; Han, D.C.; Kwon, B.M. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells. Cancer Res. 2009, 69, 193-202.
-
(2009)
Cancer Res
, vol.69
, pp. 193-202
-
-
Shin, D.S.1
Kim, H.N.2
Shin, K.D.3
Yoon, Y.J.4
Kim, S.J.5
Han, D.C.6
Kwon, B.M.7
-
148
-
-
77957372039
-
A phase I dose-escalation study of oral BR-DIM (BioResponse 3,3'- Diindolylmethane) in castrate-resistant, non-metastatic prostate cancer
-
Heath, E.I.; Heilbrun, L.K.; Li, J.; Vaishampayan, U.; Harper, F.; Pemberton, P.; Sarkar, F.H. A phase I dose-escalation study of oral BR-DIM (BioResponse 3,3'- Diindolylmethane) in castrate-resistant, non-metastatic prostate cancer. Am. J. Transl. Res. 2010, 2, 402-411.
-
(2010)
Am. J. Transl. Res
, vol.2
, pp. 402-411
-
-
Heath, E.I.1
Heilbrun, L.K.2
Li, J.3
Vaishampayan, U.4
Harper, F.5
Pemberton, P.6
Sarkar, F.H.7
-
149
-
-
80051663254
-
Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells
-
Abdelbaqi, K.; Lack, N.; Guns, E.T.; Kotha, L.; Safe, S.; Sanderson, J.T. Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells. Prostate 2011, 71, 1401-1412.
-
(2011)
Prostate
, vol.71
, pp. 1401-1412
-
-
Abdelbaqi, K.1
Lack, N.2
Guns, E.T.3
Kotha, L.4
Safe, S.5
Sanderson, J.T.6
-
150
-
-
80052576657
-
Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells
-
Li, Y.; Kong, D.; Wang, Z.; Ahmad, A.; Bao, B.; Padhye, S.; Sarkar, F.H. Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells. Cancer Prev. Res. 2011, 4, 1495-1506.
-
(2011)
Cancer Prev. Res
, vol.4
, pp. 1495-1506
-
-
Li, Y.1
Kong, D.2
Wang, Z.3
Ahmad, A.4
Bao, B.5
Padhye, S.6
Sarkar, F.H.7
-
151
-
-
84898848365
-
Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells
-
Goldberg, A.A.; Titorenko, V.I.; Beach, A.; Abdelbaqi, K.; Safe, S.; Sanderson, J.T. Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells. Invest. New Drugs 2014, 32, 25-36.
-
(2014)
Invest. New Drugs
, vol.32
, pp. 25-36
-
-
Goldberg, A.A.1
Titorenko, V.I.2
Beach, A.3
Abdelbaqi, K.4
Safe, S.5
Sanderson, J.T.6
-
152
-
-
84898889926
-
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells
-
Wong, C.P.; Hsu, A.; Buchanan, A.; Palomera-Sanchez, Z.; Beaver, L.M.; Houseman, E.A.; Williams, D.E.; Dashwood, R.H.; Ho, E. Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells. PLoS One 2014, 9, e86787.
-
(2014)
PLoS One
, vol.9
-
-
Wong, C.P.1
Hsu, A.2
Buchanan, A.3
Palomera-Sanchez, Z.4
Beaver, L.M.5
Houseman, E.A.6
Williams, D.E.7
Dashwood, R.H.8
Ho, E.9
-
153
-
-
85008726865
-
Regulation of Janus-activated kinase-2 (JAK2) by diindolylmethane in ovarian cancer in vitro and in vivo
-
Kandala, P.K.; Srivastava, S.K. Regulation of Janus-activated kinase-2 (JAK2) by diindolylmethane in ovarian cancer in vitro and in vivo. Drug Discov. Ther. 2012, 6, 94-101.
-
(2012)
Drug Discov. Ther
, vol.6
, pp. 94-101
-
-
Kandala, P.K.1
Srivastava, S.K.2
-
154
-
-
84865161024
-
Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2
-
Liu, K.; Park, C.; Li, S.; Lee, K.W.; Liu, H.; He, L.; Soung, N.K.; Ahn, J.S.; Bode, A.M.; Dong, Z. et al. Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2. Carcinogenesis 2012, 33, 1406-1411.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1406-1411
-
-
Liu, K.1
Park, C.2
Li, S.3
Lee, K.W.4
Liu, H.5
He, L.6
Soung, N.K.7
Ahn, J.S.8
Bode, A.M.9
Dong, Z.10
-
155
-
-
16844386205
-
Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth
-
Cha, T.L.; Qiu, L.; Chen, C.T.; Wen, Y.; Hung, M.C. Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth. Cancer Res. 2005, 65, 2287-2295.
-
(2005)
Cancer Res
, vol.65
, pp. 2287-2295
-
-
Cha, T.L.1
Qiu, L.2
Chen, C.T.3
Wen, Y.4
Hung, M.C.5
-
156
-
-
34147152865
-
Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor
-
Muto, A.; Hori, M.; Sasaki, Y.; Saitoh, A.; Yasuda, I.; Maekawa, T.; Uchida, T.; Asakura, K.; Nakazato, T.; Kaneda, T. et al. Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor. Mol. Cancer Ther. 2007, 6, 987-994.
-
(2007)
Mol. Cancer Ther
, vol.6
, pp. 987-994
-
-
Muto, A.1
Hori, M.2
Sasaki, Y.3
Saitoh, A.4
Yasuda, I.5
Maekawa, T.6
Uchida, T.7
Asakura, K.8
Nakazato, T.9
Kaneda, T.10
-
157
-
-
84860187078
-
Castration-resistant prostate cancer: Systemic therapy in 2012
-
Maluf, F.C.; Smaletz, O.; Herchenhorn, D. Castration-resistant prostate cancer: Systemic therapy in 2012. Clinics 2012, 67, 389-394.
-
(2012)
Clinics
, vol.67
, pp. 389-394
-
-
Maluf, F.C.1
Smaletz, O.2
Herchenhorn, D.3
-
158
-
-
77958126831
-
Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling
-
Walker, S.R.; Chaudhury, M.; Nelson, E.A.; Frank, D.A. Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling. Mol. Pharmacol. 2010, 78, 903-908.
-
(2010)
Mol. Pharmacol
, vol.78
, pp. 903-908
-
-
Walker, S.R.1
Chaudhury, M.2
Nelson, E.A.3
Frank, D.A.4
-
159
-
-
2942554803
-
Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP
-
Kan, S.F.; Huang, W.J.; Lin, L.C.; Wang, P.S. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP. Int. J. Cancer 2004, 110, 641-651.
-
(2004)
Int. J. Cancer
, vol.110
, pp. 641-651
-
-
Kan, S.F.1
Huang, W.J.2
Lin, L.C.3
Wang, P.S.4
-
160
-
-
10344234253
-
Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine
-
Huang, D.M.; Cai, X.; Lu, W.; Hu, C.; Xu, X.; Yu, Q.; Cao, P. Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine. J. Urol. 2005, 173, 256-261.
-
(2005)
J. Urol
, vol.173
, pp. 256-261
-
-
Huang, D.M.1
Cai, X.2
Lu, W.3
Hu, C.4
Xu, X.5
Yu, Q.6
Cao, P.7
-
161
-
-
84870364791
-
Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells
-
Yang, J.; Renaud, M.; Sanderson, J.T. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. Cancer Lett. 2013, 328, 243-251.
-
(2013)
Cancer Lett
, vol.328
, pp. 243-251
-
-
Yang, J.1
Renaud, M.2
Sanderson, J.T.3
-
162
-
-
20944435625
-
Indirubin derivatives inhibit STAT3 signaling and induce apoptosis in human cancer cells
-
Nam, S.; Buettner, R.; Turkson, J.; Kim, D.; Cheng, J.Q.; Muehlbeyer, S.; Hippe, F.; Vatter, S.; Merz, K.H.; Eisenbrand, G. et al. Indirubin derivatives inhibit STAT3 signaling and induce apoptosis in human cancer cells. Proc. Natl. Acad. Sci. USA 2005, 102, 5998-6003.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5998-6003
-
-
Nam, S.1
Buettner, R.2
Turkson, J.3
Kim, D.4
Cheng, J.Q.5
Muehlbeyer, S.6
Hippe, F.7
Vatter, S.8
Merz, K.H.9
Eisenbrand, G.10
-
163
-
-
79551516170
-
Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations
-
Rivest, P.; Renaud, M.; Sanderson, J.T. Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations. Chem. Biol. Interact. 2011, 189, 177-185.
-
(2011)
Chem. Biol. Interact
, vol.189
, pp. 177-185
-
-
Rivest, P.1
Renaud, M.2
Sanderson, J.T.3
-
164
-
-
84875458307
-
A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation
-
Zhang, X.; Sun, Y.; Pireddu, R.; Yang, H.; Urlam, M.K.; Lawrence, H.R.; Guida, W.C.; Lawrence, N.J.; Sebti, S.M. A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation. Cancer Res. 2013, 73, 1922-1933.
-
(2013)
Cancer Res
, vol.73
, pp. 1922-1933
-
-
Zhang, X.1
Sun, Y.2
Pireddu, R.3
Yang, H.4
Urlam, M.K.5
Lawrence, H.R.6
Guida, W.C.7
Lawrence, N.J.8
Sebti, S.M.9
-
165
-
-
33750982120
-
Stattic: A small-molecule inhibitor of STAT3 activation and dimerization
-
Schust, J.; Sperl, B.; Hollis, A.; Mayer, T.U.; Berg, T. Stattic: A small-molecule inhibitor of STAT3 activation and dimerization. Chem. Biol. 2006, 13, 1235-1242.
-
(2006)
Chem. Biol
, vol.13
, pp. 1235-1242
-
-
Schust, J.1
Sperl, B.2
Hollis, A.3
Mayer, T.U.4
Berg, T.5
-
166
-
-
37549062631
-
Design, synthesis, and studies of small molecule STAT3 inhibitors
-
Bhasin, D.; Cisek, K.; Pandharkar, T.; Regan, N.; Li, C.; Pandit, B.; Lin, J.; Li, P.K. Design, synthesis, and studies of small molecule STAT3 inhibitors. Bioorg. Med. Chem. Lett. 2008, 18, 391-395.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, pp. 391-395
-
-
Bhasin, D.1
Cisek, K.2
Pandharkar, T.3
Regan, N.4
Li, C.5
Pandit, B.6
Lin, J.7
Li, P.K.8
-
167
-
-
16344380754
-
A low-molecular-weight compound discovered through virtual database screening inhibits STAT3 function in breast cancer cells
-
Song, H.; Wang, R.; Wang, S.; Lin, J. A low-molecular-weight compound discovered through virtual database screening inhibits STAT3 function in breast cancer cells. Proc. Natl. Acad. Sci. USA 2005, 102, 4700-4705.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4700-4705
-
-
Song, H.1
Wang, R.2
Wang, S.3
Lin, J.4
-
168
-
-
34250658084
-
Selective chemical probe inhibitor of STAT3, identified through structure-based virtual screening, induces antitumor activity
-
Siddiquee, K.; Zhang, S.; Guida, W.C.; Blaskovich, M.A.; Greedy, B.; Lawrence, H.R.; Yip, M.L.; Jove, R.; McLaughlin, M.M.; Lawrence, N.J. et al. Selective chemical probe inhibitor of STAT3, identified through structure-based virtual screening, induces antitumor activity. Proc. Natl. Acad. Sci. USA 2007, 104, 7391-7396.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 7391-7396
-
-
Siddiquee, K.1
Zhang, S.2
Guida, W.C.3
Blaskovich, M.A.4
Greedy, B.5
Lawrence, H.R.6
Yip, M.L.7
Jove, R.8
McLaughlin, M.M.9
Lawrence, N.J.10
-
169
-
-
84862193781
-
Orally bioavailable small-molecule inhibitor of transcription factor STAT3 regresses human breast and lung cancer xenografts
-
Zhang, X.; Yue, P.; Page, B.D.; Li, T.; Zhao, W.; Namanja, A.T.; Paladino, D.; Zhao, J.; Chen, Y.; Gunning, P.T. et al. Orally bioavailable small-molecule inhibitor of transcription factor STAT3 regresses human breast and lung cancer xenografts. Proc. Natl. Acad. Sci. USA 2012, 109, 9623-9628.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9623-9628
-
-
Zhang, X.1
Yue, P.2
Page, B.D.3
Li, T.4
Zhao, W.5
Namanja, A.T.6
Paladino, D.7
Zhao, J.8
Chen, Y.9
Gunning, P.T.10
-
170
-
-
73949111590
-
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells
-
Lin, L.; Hutzen, B.; Li, P.K.; Ball, S.; Zuo, M.; DeAngelis, S.; Foust, E.; Sobo, M.; Friedman, L.; Bhasin, D. et al. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Neoplasia 2010, 12, 39-50.
-
(2010)
Neoplasia
, vol.12
, pp. 39-50
-
-
Lin, L.1
Hutzen, B.2
Li, P.K.3
Ball, S.4
Zuo, M.5
Deangelis, S.6
Foust, E.7
Sobo, M.8
Friedman, L.9
Bhasin, D.10
-
171
-
-
84898892592
-
The effect of selective JAK2 inhibitor SAR302503 on tumorigenic STAT3 signaling in human prostate cancer in vivo
-
San Fransisco, CA, USA, 30 January-1 February
-
Moreira, D. The effect of selective JAK2 inhibitor SAR302503 on tumorigenic STAT3 signaling in human prostate cancer in vivo. In Proceedings of the 2014 Genitourinary Cancers Symposium, San Fransisco, CA, USA, 30 January-1 February 2014.
-
(2014)
Proceedings of the 2014 Genitourinary Cancers Symposium
-
-
Moreira, D.1
-
172
-
-
84895472517
-
Overcoming AC220 resistance of FLT3-ITD by SAR302503
-
Kesarwani, M.; Huber, E.; Azam, M. Overcoming AC220 resistance of FLT3-ITD by SAR302503. Blood Cancer J. 2013, 3, e138.
-
(2013)
Blood Cancer J
, vol.3
-
-
Kesarwani, M.1
Huber, E.2
Azam, M.3
-
173
-
-
47249129126
-
LS104, a non-ATP-competitive small-molecule inhibitor of JAK2, is potently inducing apoptosis in JAK2V617F-positive cells
-
Lipka, D.B.; Hoffmann, L.S.; Heidel, F.; Markova, B.; Blum, M.C.; Breitenbuecher, F.; Kasper, S.; Kindler, T.; Levine, R.L.; Huber, C. et al. LS104, a non-ATP-competitive small-molecule inhibitor of JAK2, is potently inducing apoptosis in JAK2V617F-positive cells. Mol. Cancer Ther. 2008, 7, 1176-1184.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 1176-1184
-
-
Lipka, D.B.1
Hoffmann, L.S.2
Heidel, F.3
Markova, B.4
Blum, M.C.5
Breitenbuecher, F.6
Kasper, S.7
Kindler, T.8
Levine, R.L.9
Huber, C.10
-
175
-
-
23044478114
-
Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells
-
Amit-Vazina, M.; Shishodia, S.; Harris, D.; Van, Q.; Wang, M.; Weber, D.; Alexanian, R.; Talpaz, M.; Aggarwal, B.B.; Estrov, Z. Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells. Br. J. Cancer 2005, 93, 70-80.
-
(2005)
Br. J. Cancer
, vol.93
, pp. 70-80
-
-
Amit-Vazina, M.1
Shishodia, S.2
Harris, D.3
Van, Q.4
Wang, M.5
Weber, D.6
Alexanian, R.7
Talpaz, M.8
Aggarwal, B.B.9
Estrov, Z.10
-
176
-
-
33750739781
-
Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells
-
Faderl, S.; Shishodia, S.; Harris, D.; Van, Q.; Wang, M.; Weber, D.; Alexanian, R.; Talpaz, M.; Aggarwal, B.B.; Estrov, Z. Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells. Leuk Res. 2007, 31, 91-95.
-
(2007)
Leuk Res
, vol.31
, pp. 91-95
-
-
Faderl, S.1
Shishodia, S.2
Harris, D.3
Van, Q.4
Wang, M.5
Weber, D.6
Alexanian, R.7
Talpaz, M.8
Aggarwal, B.B.9
Estrov, Z.10
-
177
-
-
84856076374
-
Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor
-
Quintas-Cardama, A.; Manshouri, T.; Estrov, Z.; Harris, D.; Zhang, Y.; Gaikwad, A.; Kantarjian, H.M.; Verstovsek, S. Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor. Invest. New Drugs 2011, 29, 818-826.
-
(2011)
Invest. New Drugs
, vol.29
, pp. 818-826
-
-
Quintas-Cardama, A.1
Manshouri, T.2
Estrov, Z.3
Harris, D.4
Zhang, Y.5
Gaikwad, A.6
Kantarjian, H.M.7
Verstovsek, S.8
-
179
-
-
84859979617
-
Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells
-
Kohler, J.; Erlenkamp, G.; Eberlin, A.; Rumpf, T.; Slynko, I.; Metzger, E.; Schule, R.; Sippl, W.; Jung, M. Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells. PLoS One 2012, 7, e34973.
-
(2012)
PLoS One
, vol.7
-
-
Kohler, J.1
Erlenkamp, G.2
Eberlin, A.3
Rumpf, T.4
Slynko, I.5
Metzger, E.6
Schule, R.7
Sippl, W.8
Jung, M.9
-
180
-
-
79955394571
-
Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis
-
Diaz, T.; Navarro, A.; Ferrer, G.; Gel, B.; Gaya, A.; Artells, R.; Bellosillo, B.; Garcia-Garcia, M.; Serrano, S.; Martinez, A. et al. Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis. PLoS One 2011, 6, e18856.
-
(2011)
PLoS One
, vol.6
-
-
Diaz, T.1
Navarro, A.2
Ferrer, G.3
Gel, B.4
Gaya, A.5
Artells, R.6
Bellosillo, B.7
Garcia-Garcia, M.8
Serrano, S.9
Martinez, A.10
-
181
-
-
80052163169
-
+ T lymphocyte cytokine production
-
doi:10.1186/1471-2172-12-51
-
+ T lymphocyte cytokine production. BMC Immunol. 2011, 12, doi:10.1186/1471-2172-12-51.
-
(2011)
BMC Immunol
, pp. 12
-
-
Migita, K.1
Miyashita, T.2
Izumi, Y.3
Koga, T.4
Komori, A.5
Maeda, Y.6
Jiuchi, Y.7
Aiba, Y.8
Yamasaki, S.9
Kawakami, A.10
-
182
-
-
83555174315
-
The novel JAK inhibitor CYT387 suppresses multiple signalling pathways, prevents proliferation and induces apoptosis in phenotypically diverse myeloma cells
-
Monaghan, K.A.; Khong, T.; Burns, C.J.; Spencer, A. The novel JAK inhibitor CYT387 suppresses multiple signalling pathways, prevents proliferation and induces apoptosis in phenotypically diverse myeloma cells. Leukemia 2011, 25, 1891-1899.
-
(2011)
Leukemia
, vol.25
, pp. 1891-1899
-
-
Monaghan, K.A.1
Khong, T.2
Burns, C.J.3
Spencer, A.4
-
183
-
-
84856886046
-
Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia
-
Hart, S.; Goh, K.C.; Novotny-Diermayr, V.; Tan, Y.C.; Madan, B.; Amalini, C.; Ong, L.C.; Kheng, B.; Cheong, A.; Zhou, J. et al. Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia. Blood Cancer J. 2011, 1, e44.
-
(2011)
Blood Cancer J
, vol.1
-
-
Hart, S.1
Goh, K.C.2
Novotny-Diermayr, V.3
Tan, Y.C.4
Madan, B.5
Amalini, C.6
Ong, L.C.7
Kheng, B.8
Cheong, A.9
Zhou, J.10
-
184
-
-
84862165045
-
New developments in castrate-resistant prostate cancer
-
Shore, N.; Mason, M.; de Reijke, T.M. New developments in castrate-resistant prostate cancer. BJU Int. 2012, 109, 22-32.
-
(2012)
BJU Int
, vol.109
, pp. 22-32
-
-
Shore, N.1
Mason, M.2
de Reijke, T.M.3
-
185
-
-
77950833182
-
Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3
-
Yang, F.; Brown, C.; Buettner, R.; Hedvat, M.; Starr, R.; Scuto, A.; Schroeder, A.; Jensen, M.; Jove, R. Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3. Mol. Cancer Ther. 2010, 9, 953-962.
-
(2010)
Mol. Cancer Ther
, vol.9
, pp. 953-962
-
-
Yang, F.1
Brown, C.2
Buettner, R.3
Hedvat, M.4
Starr, R.5
Scuto, A.6
Schroeder, A.7
Jensen, M.8
Jove, R.9
-
186
-
-
70949094349
-
The JAK2 inhibitor AZD1480 potently blocks STAT3 signaling and oncogenesis in solid tumors
-
Hedvat, M.; Huszar, D.; Herrmann, A.; Gozgit, J.M.; Schroeder, A.; Sheehy, A.; Buettner, R.; Proia, D.; Kowolik, C.M.; Xin, H. et al. The JAK2 inhibitor AZD1480 potently blocks STAT3 signaling and oncogenesis in solid tumors. Cancer Cell 2009, 16, 487-497.
-
(2009)
Cancer Cell
, vol.16
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
Sheehy, A.6
Buettner, R.7
Proia, D.8
Kowolik, C.M.9
Xin, H.10
-
187
-
-
84886392415
-
Pharmacologic inhibition of JAK2-STAT5 signaling By JAK2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer
-
Gu, L.; Liao, Z.; Hoang, D.T.; Dagvadorj, A.; Gupta, S.; Blackmon, S.; Ellsworth, E.; Talati, P.; Leiby, B.; Zinda, M. et al. Pharmacologic inhibition of JAK2-STAT5 signaling By JAK2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer. Clin. Cancer Res. 2013, 19, 5658-5674.
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 5658-5674
-
-
Gu, L.1
Liao, Z.2
Hoang, D.T.3
Dagvadorj, A.4
Gupta, S.5
Blackmon, S.6
Ellsworth, E.7
Talati, P.8
Leiby, B.9
Zinda, M.10
-
188
-
-
84874742657
-
Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells
-
Kim, N.H.; Park, H.J.; Oh, M.K.; Kim, I.S. Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells. BMB Rep. 2013, 46, 59-64.
-
(2013)
BMB Rep
, vol.46
, pp. 59-64
-
-
Kim, N.H.1
Park, H.J.2
Oh, M.K.3
Kim, I.S.4
-
189
-
-
35948995412
-
Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3
-
Kim, N.H.; Lee, M.Y.; Park, S.J.; Choi, J.S.; Oh, M.K.; Kim, I.S. Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3. Immunology 2007, 122, 607-614.
-
(2007)
Immunology
, vol.122
, pp. 607-614
-
-
Kim, N.H.1
Lee, M.Y.2
Park, S.J.3
Choi, J.S.4
Oh, M.K.5
Kim, I.S.6
-
190
-
-
4243156987
-
Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines
-
Barton, B.E.; Karras, J.G.; Murphy, T.F.; Barton, A.; Huang, H.F. Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines. Mol. Cancer Ther. 2004, 3, 11-20.
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 11-20
-
-
Barton, B.E.1
Karras, J.G.2
Murphy, T.F.3
Barton, A.4
Huang, H.F.5
-
191
-
-
0030978808
-
Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits STAT3 activation and growth of mycosis fungoides tumor cell lines
-
Nielsen, M.; Kaltoft, K.; Nordahl, M.; Ropke, C.; Geisler, C.; Mustelin, T.; Dobson, P.; Svejgaard, A.; Odum, N. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits STAT3 activation and growth of mycosis fungoides tumor cell lines. Proc. Natl. Acad. Sci. USA 1997, 94, 6764-6769.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6764-6769
-
-
Nielsen, M.1
Kaltoft, K.2
Nordahl, M.3
Ropke, C.4
Geisler, C.5
Mustelin, T.6
Dobson, P.7
Svejgaard, A.8
Odum, N.9
-
192
-
-
84880692649
-
Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting
-
Kurosaka, M.; Machida, S. Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting. Cell Prolif. 2013, 46, 365-373.
-
(2013)
Cell Prolif
, vol.46
, pp. 365-373
-
-
Kurosaka, M.1
Machida, S.2
-
193
-
-
79959269602
-
Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells
-
Liu, A.; Liu, Y.; Xu, Z.; Yu, W.; Wang, H.; Li, C.; Lin, J. Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells. Cancer Sci. 2011, 102, 1381-1387.
-
(2011)
Cancer Sci
, vol.102
, pp. 1381-1387
-
-
Liu, A.1
Liu, Y.2
Xu, Z.3
Yu, W.4
Wang, H.5
Li, C.6
Lin, J.7
-
194
-
-
84867046550
-
XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells
-
Liu, A.; Liu, Y.; Jin, Z.; Hu, Q.; Lin, L.; Jou, D.; Yang, J.; Xu, Z.; Wang, H.; Li, C. et al. XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells. PLoS One 2012, 7, e46624.
-
(2012)
PLoS One
, vol.7
-
-
Liu, A.1
Liu, Y.2
Jin, Z.3
Hu, Q.4
Lin, L.5
Jou, D.6
Yang, J.7
Xu, Z.8
Wang, H.9
Li, C.10
-
195
-
-
77950190311
-
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells
-
Lin, L.; Hutzen, B.; Zuo, M.; Ball, S.; Deangelis, S.; Foust, E.; Pandit, B.; Ihnat, M.A.; Shenoy, S.S.; Kulp, S. et al. Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells. Cancer Res. 2010, 70, 2445-2454.
-
(2010)
Cancer Res
, vol.70
, pp. 2445-2454
-
-
Lin, L.1
Hutzen, B.2
Zuo, M.3
Ball, S.4
Deangelis, S.5
Foust, E.6
Pandit, B.7
Ihnat, M.A.8
Shenoy, S.S.9
Kulp, S.10
-
196
-
-
84856696839
-
Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2
-
Purandare, A.V.; McDevitt, T.M.; Wan, H.; You, D.; Penhallow, B.; Han, X.; Vuppugalla, R.; Zhang, Y.; Ruepp, S.U.; Trainor, G.L. et al. Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2. Leukemia 2012, 26, 280-288.
-
(2012)
Leukemia
, vol.26
, pp. 280-288
-
-
Purandare, A.V.1
McDevitt, T.M.2
Wan, H.3
You, D.4
Penhallow, B.5
Han, X.6
Vuppugalla, R.7
Zhang, Y.8
Ruepp, S.U.9
Trainor, G.L.10
-
197
-
-
85064289101
-
Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
-
Furqan, M.; Mukhi, N.; Lee, B.; Liu, D. Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application. Biomark Res. 2013, 1, e5.
-
(2013)
Biomark Res
, vol.1
-
-
Furqan, M.1
Mukhi, N.2
Lee, B.3
Liu, D.4
-
198
-
-
79954620949
-
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis
-
Stump, K.L.; Lu, L.D.; Dobrzanski, P.; Serdikoff, C.; Gingrich, D.E.; Dugan, B.J.; Angeles, T.S.; Albom, M.S.; Ator, M.A.; Dorsey, B.D. et al. A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis. Arthritis Res. Ther. 2011, 13, R68.
-
(2011)
Arthritis Res. Ther
, vol.13
-
-
Stump, K.L.1
Lu, L.D.2
Dobrzanski, P.3
Serdikoff, C.4
Gingrich, D.E.5
Dugan, B.J.6
Angeles, T.S.7
Albom, M.S.8
Ator, M.A.9
Dorsey, B.D.10
-
199
-
-
84862271596
-
Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer
-
Seavey, M.M.; Lu, L.D.; Stump, K.L.; Wallace, N.H.; Hockeimer, W.; O'Kane, T.M.; Ruggeri, B.A.; Dobrzanski, P. Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer. Mol. Cancer Ther. 2012, 11, 984-993.
-
(2012)
Mol. Cancer Ther
, vol.11
, pp. 984-993
-
-
Seavey, M.M.1
Lu, L.D.2
Stump, K.L.3
Wallace, N.H.4
Hockeimer, W.5
O'Kane, T.M.6
Ruggeri, B.A.7
Dobrzanski, P.8
-
200
-
-
84862287729
-
A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: Discovery of CEP-33779
-
Dugan, B.J.; Gingrich, D.E.; Mesaros, E.F.; Milkiewicz, K.L.; Curry, M.A.; Zulli, A.L.; Dobrzanski, P.; Serdikoff, C.; Jan, M.; Angeles, T.S. et al. A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: Discovery of CEP-33779. J. Med. Chem. 2012, 55, 5243-5254.
-
(2012)
J. Med. Chem
, vol.55
, pp. 5243-5254
-
-
Dugan, B.J.1
Gingrich, D.E.2
Mesaros, E.F.3
Milkiewicz, K.L.4
Curry, M.A.5
Zulli, A.L.6
Dobrzanski, P.7
Serdikoff, C.8
Jan, M.9
Angeles, T.S.10
-
201
-
-
84868250804
-
Dynamic changes in the secondary structure of ECE-1 and XCE account for their different substrate specificities
-
doi:10.1186/1471-2105-13-285
-
Ul-Haq, Z.; Iqbal, S.; Moin, S.T. Dynamic changes in the secondary structure of ECE-1 and XCE account for their different substrate specificities. BMC Bioinforma. 2012, 13, doi:10.1186/1471-2105-13-285.
-
(2012)
BMC Bioinforma
, pp. 13
-
-
Ul-Haq, Z.1
Iqbal, S.2
Moin, S.T.3
-
202
-
-
79959528659
-
R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm
-
Shide, K.; Kameda, T.; Markovtsov, V.; Shimoda, H.K.; Tonkin, E.; Fang, S.; Liu, C.; Gelman, M.; Lang, W.; Romero, J. et al. R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm. Blood 2011, 117, 6866-6875.
-
(2011)
Blood
, vol.117
, pp. 6866-6875
-
-
Shide, K.1
Kameda, T.2
Markovtsov, V.3
Shimoda, H.K.4
Tonkin, E.5
Fang, S.6
Liu, C.7
Gelman, M.8
Lang, W.9
Romero, J.10
-
203
-
-
0032922590
-
Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity
-
Borsellino, N.; Bonavida, B.; Ciliberto, G.; Toniatti, C.; Travali, S.; D'Alessandro, N. Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity. Cancer 1999, 85, 134-144.
-
(1999)
Cancer
, vol.85
, pp. 134-144
-
-
Borsellino, N.1
Bonavida, B.2
Ciliberto, G.3
Toniatti, C.4
Travali, S.5
D'Alessandro, N.6
-
204
-
-
0036839144
-
In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway
-
Chatterjee, M.; Honemann, D.; Lentzsch, S.; Bommert, K.; Sers, C.; Herrmann, P.; Mathas, S.; Dorken, B.; Bargou, R.C. In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway. Blood 2002, 100, 3311-3318.
-
(2002)
Blood
, vol.100
, pp. 3311-3318
-
-
Chatterjee, M.1
Honemann, D.2
Lentzsch, S.3
Bommert, K.4
Sers, C.5
Herrmann, P.6
Mathas, S.7
Dorken, B.8
Bargou, R.C.9
-
205
-
-
84876117522
-
Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression
-
Oguro, T.; Ishibashi, K.; Sugino, T.; Hashimoto, K.; Tomita, S.; Takahashi, N.; Yanagida, T.; Haga, N.; Aikawa, K.; Suzutani, T. et al. Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression. Eur. J. Cancer 2013, 49, 1715-1724.
-
(2013)
Eur. J. Cancer
, vol.49
, pp. 1715-1724
-
-
Oguro, T.1
Ishibashi, K.2
Sugino, T.3
Hashimoto, K.4
Tomita, S.5
Takahashi, N.6
Yanagida, T.7
Haga, N.8
Aikawa, K.9
Suzutani, T.10
-
206
-
-
79955780881
-
JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling
-
Song, L.; Rawal, B.; Nemeth, J.A.; Haura, E.B. JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling. Mol. Cancer Ther. 2011, 10, 481-494.
-
(2011)
Mol. Cancer Ther
, vol.10
, pp. 481-494
-
-
Song, L.1
Rawal, B.2
Nemeth, J.A.3
Haura, E.B.4
-
207
-
-
84875266301
-
New strategies against prostate cancer-Pt(II)-based chemotherapy
-
Matos, C.S.; de Carvalho, A.L.; Lopes, R.P.; Marques, M.P. New strategies against prostate cancer-Pt(II)-based chemotherapy. Curr. Med. Chem. 2012, 19, 4678-4687.
-
(2012)
Curr. Med. Chem
, vol.19
, pp. 4678-4687
-
-
Matos, C.S.1
de Carvalho, A.L.2
Lopes, R.P.3
Marques, M.P.4
-
208
-
-
80052197203
-
Small molecule inhibitors of STAT3 for cancer therapy
-
Zhao, M.; Jiang, B.; Gao, F.H. Small molecule inhibitors of STAT3 for cancer therapy. Curr. Med. Chem. 2011, 18, 4012-4018.
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 4012-4018
-
-
Zhao, M.1
Jiang, B.2
Gao, F.H.3
-
209
-
-
12344328541
-
Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
-
Turkson, J.; Zhang, S.; Palmer, J.; Kay, H.; Stanko, J.; Mora, L.B.; Sebti, S.; Yu, H.; Jove, R. Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity. Mol. Cancer Ther. 2004, 3, 1533-1542.
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 1533-1542
-
-
Turkson, J.1
Zhang, S.2
Palmer, J.3
Kay, H.4
Stanko, J.5
Mora, L.B.6
Sebti, S.7
Yu, H.8
Jove, R.9
-
210
-
-
84858230349
-
A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line
-
Souissi, I.; Ladam, P.; Cognet, J.A.; Le Coquil, S.; Varin-Blank, N.; Baran-Marszak, F.; Metelev, V.; Fagard, R. A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line. Mol. Cancer 2012, 11, e12.
-
(2012)
Mol. Cancer
, vol.11
-
-
Souissi, I.1
Ladam, P.2
Cognet, J.A.3
Le Coquil, S.4
Varin-Blank, N.5
Baran-Marszak, F.6
Metelev, V.7
Fagard, R.8
-
211
-
-
84866254673
-
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: Implications for cancer therapy
-
Sen, M.; Thomas, S.M.; Kim, S.; Yeh, J.I.; Ferris, R.L.; Johnson, J.T.; Duvvuri, U.; Lee, J.; Sahu, N.; Joyce, S.; et al. First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: Implications for cancer therapy. Cancer Discov. 2012, 2, 694-705.
-
(2012)
Cancer Discov
, vol.2
, pp. 694-705
-
-
Sen, M.1
Thomas, S.M.2
Kim, S.3
Yeh, J.I.4
Ferris, R.L.5
Johnson, J.T.6
Duvvuri, U.7
Lee, J.8
Sahu, N.9
Joyce, S.10
-
212
-
-
4644325545
-
G-quartet oligonucleotides: A new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis
-
Jing, N.; Thomas, S.M.; Kim, S.; Yeh, J.I.; Ferris, R.L.; Johnson, J.T.; Duvvuri, U.; Lee, J.; Sahu, N.; Joyce, S. G-quartet oligonucleotides: A new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis. Cancer Res. 2004, 64, 6603-6609.
-
(2004)
Cancer Res
, vol.64
, pp. 6603-6609
-
-
Jing, N.1
Thomas, S.M.2
Kim, S.3
Yeh, J.I.4
Ferris, R.L.5
Johnson, J.T.6
Duvvuri, U.7
Lee, J.8
Sahu, N.9
Joyce, S.10
-
213
-
-
0344984245
-
Targeting Stat3 With G-quartet Oligodeoxynucleotides In Human Cancer Cells
-
Jing, N.; Li, Y.; Xu, X.; Sha, W.; Li, P.; Feng, L.; Tweardy, D.J. Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells. DNA Cell. Biol. 2003, 22, 685-696.
-
(2003)
DNA Cell. Biol
, vol.22
, pp. 685-696
-
-
Jing, N.1
Li, Y.2
Xu, X.3
Sha, W.4
Li, P.5
Feng, L.6
Tweardy, D.J.7
-
214
-
-
79955673922
-
Plasmid-based Stat3 siRNA delivered by hydroxyapatite nanoparticles suppresses mouse prostate tumour growth in vivo
-
Liang, Z.W.; Guo, B.F.; Li, Y.; Li, X.J.; Li, X.; Zhao, L.J.; Gao, L.F.; Yu, H.; Zhao, X.J.; Zhang, L. et al. Plasmid-based Stat3 siRNA delivered by hydroxyapatite nanoparticles suppresses mouse prostate tumour growth in vivo. Asian J. Androl. 2011, 13, 481-486.
-
(2011)
Asian J. Androl
, vol.13
, pp. 481-486
-
-
Liang, Z.W.1
Guo, B.F.2
Li, Y.3
Li, X.J.4
Li, X.5
Zhao, L.J.6
Gao, L.F.7
Yu, H.8
Zhao, X.J.9
Zhang, L.10
-
215
-
-
3943103442
-
RNA interference targeting STAT3 inhibits growth and induces apoptosis of human prostate cancer cells
-
Lee, S.O.; Lou, W.; Qureshi, K.M.; Mehraein-Ghomi, F.; Trump, D.L.; Gao, A.C. RNA interference targeting STAT3 inhibits growth and induces apoptosis of human prostate cancer cells. Prostate 2004, 60, 303-309.
-
(2004)
Prostate
, vol.60
, pp. 303-309
-
-
Lee, S.O.1
Lou, W.2
Qureshi, K.M.3
Mehraein-Ghomi, F.4
Trump, D.L.5
Gao, A.C.6
-
216
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
Konnikova, L.; Kotecki, M.; Kruger, M.M.; Cochran, B.H. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 2003, 3, e23.
-
(2003)
BMC Cancer
, vol.3
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
217
-
-
84891769689
-
Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity
-
Hossain, D.M.; dos Santos, C.; Zhang, Q.; Kozlowska, A.; Liu, H.; Gao, C.; Moreira, D.; Swiderski, P.; Jozwiak, A.; Kline, J. et al. Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity. Blood 2014, 123, 15-25.
-
(2014)
Blood
, vol.123
, pp. 15-25
-
-
Hossain, D.M.1
Dos Santos, C.2
Zhang, Q.3
Kozlowska, A.4
Liu, H.5
Gao, C.6
Moreira, D.7
Swiderski, P.8
Jozwiak, A.9
Kline, J.10
-
218
-
-
84874449237
-
TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo
-
Zhang, Q.; Hossain, D.M.; Nechaev, S.; Kozlowska, A.; Zhang, W.; Liu, Y.; Kowolik, C.M.; Swiderski, P.; Rossi, J.J.; Forman, S. et al. TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo. Blood 2013, 121, 1304-1315.
-
(2013)
Blood
, vol.121
, pp. 1304-1315
-
-
Zhang, Q.1
Hossain, D.M.2
Nechaev, S.3
Kozlowska, A.4
Zhang, W.5
Liu, Y.6
Kowolik, C.M.7
Swiderski, P.8
Rossi, J.J.9
Forman, S.10
-
219
-
-
84859877124
-
Combining immunological and androgen-directed approaches: An emerging concept in prostate cancer immunotherapy
-
Antonarakis, E.S.; Drake, C.G. Combining immunological and androgen-directed approaches: An emerging concept in prostate cancer immunotherapy. Curr. Opin. Oncol. 2012, 24, 258-265.
-
(2012)
Curr. Opin. Oncol
, vol.24
, pp. 258-265
-
-
Antonarakis, E.S.1
Drake, C.G.2
|