메뉴 건너뛰기




Volumn 71, Issue 13, 2011, Pages 1401-1412

Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3′-diindolylmethane (Ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells

Author keywords

androgen receptor; dihydrotestosterone; immunofluorescence; LNCaP cells; prostate specific antigen; ring DIMs

Indexed keywords

3,3' DIINDOLYLMETHANE; 4,4' DIBROMO 4,4' DICHLORO 7,7' DIBROMO 3,3' DIINDOLYLMETHANE; 7,7' DICHLORO 3,3' DIINDOLYLMETHANE; ANDROGEN RECEPTOR; ANTIANDROGEN; BICALUTAMIDE; CYTOPLASM PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; PROBASIN; PROSTATE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

EID: 80051663254     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21356     Document Type: Article
Times cited : (35)

References (59)
  • 1
    • 0030772022 scopus 로고    scopus 로고
    • Target to apoptosis: A hopeful weapon for prostate cancer
    • DOI 10.1002/(SICI)1097-0045(19970901)32:4<284::AID-PROS9>3.0.CO;2-J
    • Tang DG, Porter AT,. Target to apoptosis: A hopeful weapon for prostate cancer. Prostate 1997; 32 (4): 284-293. (Pubitemid 27374201)
    • (1997) Prostate , vol.32 , Issue.4 , pp. 284-293
    • Tang, D.G.1    Porter, A.T.2
  • 2
    • 0032918316 scopus 로고    scopus 로고
    • Molecular biology of progression of prostate cancer
    • DOI 10.1159/000019907
    • Nupponen N, Visakorpi T,. Molecular biology of progression of prostate cancer. Eur Urol 1999; 35 (5-6): 351-354. (Pubitemid 29229532)
    • (1999) European Urology , vol.35 , Issue.5-6 , pp. 351-354
    • Nupponen, N.1    Visakorpi, T.2
  • 4
    • 0036040438 scopus 로고    scopus 로고
    • Brassica vegetables and prostate cancer risk: A review of the epidemiological evidence
    • Kristal AR, Lampe JW,. Brassica vegetables and prostate cancer risk: A review of the epidemiological evidence. Nutr Cancer 2002; 42 (1): 1-9. (Pubitemid 35007000)
    • (2002) Nutrition and Cancer , vol.42 , Issue.1 , pp. 1-9
    • Kristal, A.R.1    Lampe, J.W.2
  • 5
    • 0028088840 scopus 로고
    • Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent
    • Tiwari RK, Guo L, Bradlow HL, Telang NT, Osborne MP,. Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent. J Natl Cancer Inst 1994; 86 (2): 126-131.
    • (1994) J Natl Cancer Inst , vol.86 , Issue.2 , pp. 126-131
    • Tiwari, R.K.1    Guo, L.2    Bradlow, H.L.3    Telang, N.T.4    Osborne, M.P.5
  • 6
    • 34047141137 scopus 로고    scopus 로고
    • Conditional Akt activation promotes androgen-independent progression of prostate cancer
    • DOI 10.1093/carcin/bgl193
    • Li B, Sun A, Youn H, Hong Y, Terranova PF, Thrasher JB, Xu P, Spencer D,. Conditional Akt activation promotes androgen-independent progression of prostate cancer. Carcinogenesis 2007; 28 (3): 572-583. (Pubitemid 46523353)
    • (2007) Carcinogenesis , vol.28 , Issue.3 , pp. 572-583
    • Li, B.1    Sun, A.2    Youn, H.3    Hong, Y.4    Terranova, P.F.5    Thrasher, J.B.6    Xu, P.7    Spencer, D.8
  • 7
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3'-diindolylmethane induce apoptosis in human prostate cancer cells
    • DOI 10.1016/S0278-6915(03)00004-8
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA,. Indole-3-carbinol and 3,3'-diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol 2003; 41 (6): 745-752. (Pubitemid 36555879)
    • (2003) Food and Chemical Toxicology , vol.41 , Issue.6 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 8
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • Bradlow HL, Michnovicz J, Telang NT, Osborne MP,. Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 1991; 12 (9): 1571-1574.
    • (1991) Carcinogenesis , vol.12 , Issue.9 , pp. 1571-1574
    • Bradlow, H.L.1    Michnovicz, J.2    Telang, N.T.3    Osborne, M.P.4
  • 9
    • 6944231023 scopus 로고    scopus 로고
    • Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway
    • DOI 10.1038/sj.bjc.6602145
    • Nachshon-Kedmi M, Yannai S, Fares FA,. Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway. Br J Cancer 2004; 91 (7): 1358-1363. (Pubitemid 39424798)
    • (2004) British Journal of Cancer , vol.91 , Issue.7 , pp. 1358-1363
    • Nachshon-Kedmi, M.1    Yannai, S.2    Fares, F.A.3
  • 10
    • 0037384508 scopus 로고    scopus 로고
    • Gene expression profiles of 13C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis
    • Li Y, Li X, Sarkar FH,. Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis. J Nutr 2003; 133 (4): 1011-1019. (Pubitemid 36407118)
    • (2003) Journal of Nutrition , vol.133 , Issue.4 , pp. 1011-1019
    • Li, Y.1    Li, X.2    Sarkar, F.H.3
  • 11
    • 0035942499 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    • DOI 10.1038/sj.onc.1204365
    • Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH,. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene 2001; 20 (23): 2927-2936. (Pubitemid 33027760)
    • (2001) Oncogene , vol.20 , Issue.23 , pp. 2927-2936
    • Chinni, S.R.1    Li, Y.2    Upadhyay, S.3    Koppolu, P.K.4    Sarkar, F.H.5
  • 12
    • 0018137952 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenberg LW, Loub WD,. Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res 1978; 38 (5): 1410-1413. (Pubitemid 8323347)
    • (1978) Cancer Research , vol.38 , Issue.5 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 13
    • 4544358789 scopus 로고    scopus 로고
    • Therapeutic activity of 3,3'-diindolylmethane on prostate cancer in an in vivo model
    • DOI 10.1002/pros.20092
    • Nachshon-Kedmi M, Fares FA, Yannai S,. Therapeutic activity of 3,3'-diindolylmethane on prostate cancer in an in vivo model. Prostate 2004; 61 (2): 153-160. (Pubitemid 39244702)
    • (2004) Prostate , vol.61 , Issue.2 , pp. 153-160
    • Nachshon-Kedmi, M.1    Fares, F.A.2    Yannai, S.3
  • 14
    • 17844381889 scopus 로고    scopus 로고
    • 3,3'-diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice
    • DOI 10.1093/carcin/bgi018
    • Chang X, Tou JC, Hong C, Kim HA, Riby JE, Firestone GL, Bjeldanes LF,. 3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice. Carcinogenesis 2005; 26 (4): 771-778. (Pubitemid 41214339)
    • (2005) Carcinogenesis , vol.26 , Issue.4 , pp. 771-778
    • Chang, X.1    Tou, J.C.2    Hong, C.3    Kim, H.-A.4    Riby, J.E.5    Firestone, G.L.6    Bjeldanes, L.F.7
  • 15
    • 2442672870 scopus 로고    scopus 로고
    • Physiological modeling of formulated and crystalline 3,3' -diindolylmethane pharmacokinetics following oral administration in mice
    • DOI 10.1124/dmd.32.6.632
    • Anderton MJ, Manson MM, Verschoyle R, Gescher A, Steward WP, Williams ML, Mager DE,. Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice. Drug Metab Dispos 2004; 32 (6): 632-638. (Pubitemid 38668156)
    • (2004) Drug Metabolism and Disposition , vol.32 , Issue.6 , pp. 632-638
    • Anderton, M.J.1    Manson, M.M.2    Verschoyle, R.3    Gescher, A.4    Steward, W.P.5    Williams, M.L.6    Mager, D.E.7
  • 16
    • 33750541268 scopus 로고    scopus 로고
    • Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-06-2011
    • Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S, Sarkar FH,. Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 2006; 66 (20): 10064-10072. (Pubitemid 44672060)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 10064-10072
    • Bhuiyan, M.M.R.1    Li, Y.2    Banerjee, S.3    Ahmed, F.4    Wang, Z.5    Ali, S.6    Sarkar, F.H.7
  • 17
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3'-diindolylmethane is mediated by the NF-κB downstream target genes MMP-9 and uPA that regulated bioavailability of VEGF in prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-4277
    • Kong D, Li Y, Wang Z, Banerjee S, Sarkar FH,. Inhibition of angiogenesis and invasion by 3,3'-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 2007; 67 (7): 3310-3319. (Pubitemid 46724870)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 18
    • 40749118374 scopus 로고    scopus 로고
    • Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants-Hakomori's concepts revisited
    • DOI 10.1016/j.bbagen.2007.10.007, PII S0304416507002395
    • Kannagi R, Yin J, Miyazaki K, Izawa M,. Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants-Hakomori's concepts revisited. Biochim Biophys Acta 2008; 1780 (3): 525-531. (Pubitemid 351381253)
    • (2008) Biochimica et Biophysica Acta - General Subjects , vol.1780 , Issue.3 , pp. 525-531
    • Kannagi, R.1    Yin, J.2    Miyazaki, K.3    Izawa, M.4
  • 19
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor γ (Troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
    • Kubota T, Koshizuka K, Williamson EA, Asou H, Said JW, Holden S, Miyoshi I, Koeffler HP,. Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res 1998; 58 (15): 3344-3352. (Pubitemid 28371075)
    • (1998) Cancer Research , vol.58 , Issue.15 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3    Asou, H.4    Said, J.W.5    Holden, S.6    Miyoshi, I.7    Koeffler, H.P.8
  • 21
    • 0035371931 scopus 로고    scopus 로고
    • Oncostatic activity of a thiazolidinedione derivative on human androgen-dependent prostate cancer cells
    • DOI 10.1002/1097-0215(20010601)92:5<733::AID-IJC1254>3.0.CO;2-L
    • Moretti RM, Montagnani Marelli M, Motta M, Limonta P,. Oncostatic activity of a thiazolidinedione derivative on human androgen-dependent prostate cancer cells. Int J Cancer 2001; 92 (5): 733-737. (Pubitemid 32385718)
    • (2001) International Journal of Cancer , vol.92 , Issue.5 , pp. 733-737
    • Moretti, R.M.1    Marelli, M.M.2    Motta, M.3    Limonta, P.4
  • 23
    • 3843122382 scopus 로고    scopus 로고
    • Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer
    • Jiang M, Shappell SB, Hayward SW,. Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer. J Cell Biochem 2004; 91 (3): 513-527.
    • (2004) J Cell Biochem , vol.91 , Issue.3 , pp. 513-527
    • Jiang, M.1    Shappell, S.B.2    Hayward, S.W.3
  • 24
    • 28744438331 scopus 로고    scopus 로고
    • WAF1/CIP1 upregulation in a human prostate epithelial cell line
    • DOI 10.1038/sj.onc.1208983
    • Jarvis MC, Gray TJ, Palmer CN,. Both PPARgamma and PPARdelta influence sulindac sulfide-mediated p21WAF1/CIP1 upregulation in a human prostate epithelial cell line. Oncogene 2005; 24 (55): 8211-8215. (Pubitemid 41759820)
    • (2005) Oncogene , vol.24 , Issue.55 , pp. 8211-8215
    • Jarvis, M.C.1    Gray, T.J.B.2    Palmer, C.N.A.3
  • 25
    • 33645803202 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells
    • Yang CC, Ku CY, Wei S, Shiau CW, Chen CS, Pinzone JJ, Ringel MD,. Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells. Mol Pharmacol 2006; 69 (5): 1564-1570.
    • (2006) Mol Pharmacol , vol.69 , Issue.5 , pp. 1564-1570
    • Yang, C.C.1    Ku, C.Y.2    Wei, S.3    Shiau, C.W.4    Chen, C.S.5    Pinzone, J.J.6    Ringel, M.D.7
  • 26
    • 0038418500 scopus 로고    scopus 로고
    • Plant-derived 3,3'-diindolylmethane is a strong androgen antagonist in human prostate cancer cells
    • DOI 10.1074/jbc.M300588200
    • Le HT, Schaldach CM, Firestone GL, Bjeldanes LF,. Plant-derived 3,3'-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 2003; 278 (23): 21136-21145. (Pubitemid 36806427)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.23 , pp. 21136-21145
    • Le, H.T.1    Schaldach, C.M.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 27
    • 0036196320 scopus 로고    scopus 로고
    • NF-κB activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer
    • DOI 10.1128/MCB.22.8.2862-2870.2002
    • Chen CD, Sawyers CL,. NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer. Mol Cell Biol 2002; 22 (8): 2862-2870. (Pubitemid 34263006)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.8 , pp. 2862-2870
    • Chen, C.D.1    Sawyers, C.L.2
  • 28
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • DOI 10.1210/er.2002-0032
    • Heinlein CA, Chang C,. Androgen receptor in prostate cancer. Endocr Rev 2004; 25 (2): 276-308. (Pubitemid 38501396)
    • (2004) Endocrine Reviews , vol.25 , Issue.2 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 29
    • 20344407552 scopus 로고    scopus 로고
    • Requirement for NF-κB interleukin-4-induced androgen receptor activation in prostate cancer cells
    • DOI 10.1002/pros.20218
    • Lee SO, Lou W, Nadiminty N, Lin X, Gao AC,. Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 2005; 64 (2): 160-167. (Pubitemid 40791765)
    • (2005) Prostate , vol.64 , Issue.2 , pp. 160-167
    • Lee, S.O.1    Lou, W.2    Nadiminty, N.3    Lin, X.4    Gao, A.C.5
  • 30
    • 0842313065 scopus 로고    scopus 로고
    • Nuclear Factor-κB Activates Transcription of the Androgen Receptor Gene in Sertoli Cells Isolated from Testes of Adult Rats
    • DOI 10.1210/en.2003-0987
    • Zhang L, Charron M, Wright WW, Chatterjee B, Song CS, Roy AK, Brown TR,. Nuclear factor-kappaB activates transcription of the androgen receptor gene in Sertoli cells isolated from testes of adult rats. Endocrinology 2004; 145 (2): 781-789. (Pubitemid 38183821)
    • (2004) Endocrinology , vol.145 , Issue.2 , pp. 781-789
    • Zhang, L.1    Charron, M.2    Wright, W.W.3    Chatterjee, B.4    Song, C.S.5    Roy, A.K.6    Brown, T.R.7
  • 31
    • 0036559864 scopus 로고    scopus 로고
    • A history of prostate cancer treatment
    • Denmeade SR, Isaacs JT,. A history of prostate cancer treatment. Nat Rev Cancer 2002; 2 (5): 389-396. (Pubitemid 37328952)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 389-396
    • Denmeade, S.R.1    Isaacs, J.T.2
  • 33
    • 9644279380 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer: Current status and future prospects
    • DOI 10.1002/pros.20115
    • Miyamoto H, Messing EM, Chang C,. Androgen deprivation therapy for prostate cancer: Current status and future prospects. Prostate 2004; 61 (4): 332-353. (Pubitemid 39571710)
    • (2004) Prostate , vol.61 , Issue.4 , pp. 332-353
    • Miyamoto, H.1    Messing, E.M.2    Chang, C.3
  • 35
    • 0034646769 scopus 로고    scopus 로고
    • Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane
    • DOI 10.1016/S0304-3835(99)00406-1, PII S0304383599004061
    • McDougal A, Sethi Gupta M, Ramamoorthy K, Sun G, Safe SH,. Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Lett 2000; 151 (2): 169-179. (Pubitemid 30156791)
    • (2000) Cancer Letters , vol.151 , Issue.2 , pp. 169-179
    • McDougal, A.1    Sethi Gupta, M.2    Ramamoorthy, K.3    Sun, G.4    Safe, S.H.5
  • 36
    • 0035016018 scopus 로고    scopus 로고
    • Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats
    • DOI 10.1023/A:1010608000074
    • McDougal A, Gupta MS, Morrow D, Ramamoorthy K, Lee JE, Safe SH,. Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats. Breast Cancer Res Treat 2001; 66 (2): 147-157. (Pubitemid 32521421)
    • (2001) Breast Cancer Research and Treatment , vol.66 , Issue.2 , pp. 147-157
    • McDougal, A.1    Gupta, M.S.2    Morrow, D.3    Ramamoorthy, K.4    Lee, J.-E.5    Safe, S.H.6
  • 37
    • 33847382319 scopus 로고    scopus 로고
    • Rapid, non-destructive, cell-based screening assays for agents that modulate growth, death, and androgen receptor activation in prostate cancer cells
    • DOI 10.1002/pros.20532
    • Tavassoli P, Snoek R, Ray M, Rao LG, Rennie PS,. Rapid, non-destructive, cell-based screening assays for agents that modulate growth, death, and androgen receptor activation in prostate cancer cells. Prostate 2007; 67 (4): 416-426. (Pubitemid 46341083)
    • (2007) Prostate , vol.67 , Issue.4 , pp. 416-426
    • Tavassoli, P.1    Snoek, R.2    Ray, M.3    Rao, L.G.4    Rennie, P.S.5
  • 38
    • 4944246790 scopus 로고    scopus 로고
    • Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer
    • DOI 10.1677/erc.1.00525
    • Scher HI, Buchanan G, Gerald W, Butler LM, Tilley WD,. Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer. Endocr Relat Cancer 2004; 11 (3): 459-476. (Pubitemid 39331277)
    • (2004) Endocrine-Related Cancer , vol.11 , Issue.3 , pp. 459-476
    • Scher, H.I.1    Buchanan, G.2    Gerald, W.3    Butler, L.M.4    Tilley, W.D.5
  • 39
    • 0029048617 scopus 로고
    • Prostate specific antigen after gonadal androgen withdrawal and deferred flutamide treatment
    • Fowler JE Jr, Pandey P, Seaver LE, Feliz TP,. Prostate specific antigen after gonadal androgen withdrawal and deferred flutamide treatment. J Urol 1995; 154 (2 Pt 1): 448-453.
    • (1995) J Urol , vol.154 , Issue.2 PART 1 , pp. 448-453
    • Fowler, Jr.J.E.1    Pandey, P.2    Seaver, L.E.3    Feliz, T.P.4
  • 40
    • 0035148171 scopus 로고    scopus 로고
    • Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: A phase III study of the European Organization for Research and Treatment of Cancer Genitourinary Group
    • Fossa SD, Slee PH, Brausi M, Horenblas S, Hall RR, Hetherington JW, Aaronson N, de Prijck L, Collette L,. Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: A Phase III Study of the European Organization for Research and Treatment of Cancer Genitourinary Group. J Clin Oncol 2001; 19 (1): 62-71. (Pubitemid 32063480)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.1 , pp. 62-71
    • Fossa, S.D.1    Brausi, S.M.2    Horenblas, S.3    Hall, R.R.4    Hetherington, J.W.5    Aaronson, N.6    De Prijck, L.7    Collette, L.8
  • 44
    • 0030948745 scopus 로고    scopus 로고
    • Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor
    • DOI 10.1016/S0303-7207(97)04034-3, PII S0303720797040343
    • Georget V, Lobaccaro JM, Terouanne B, Mangeat P, Nicolas JC, Sultan C,. Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor. Mol Cell Endocrinol 1997; 129 (1): 17-26. (Pubitemid 27229213)
    • (1997) Molecular and Cellular Endocrinology , vol.129 , Issue.1 , pp. 17-26
    • Georget, V.1    Lobaccaro, J.M.2    Terouanne, B.3    Mangeat, P.4    Nicolas, J.-C.5    Sultan, C.6
  • 45
    • 0037135630 scopus 로고    scopus 로고
    • Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor
    • DOI 10.1074/jbc.M203310200
    • Masiello D, Cheng S, Bubley GJ, Lu ML, Balk SP,. Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J Biol Chem 2002; 277 (29): 26321-26326. (Pubitemid 34967123)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26321-26326
    • Masiello, D.1    Cheng, S.2    Bubley, G.J.3    Lu, M.L.4    Balk, S.P.5
  • 46
    • 33846484297 scopus 로고    scopus 로고
    • 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor γ-independent pathways
    • DOI 10.1124/mol.106.028696
    • Chintharlapalli S, Papineni S, Safe S,. 1,1-Bis(3'-indolyl)-1-(p- substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways. Mol Pharmacol 2007; 71 (2): 558-569. (Pubitemid 46151072)
    • (2007) Molecular Pharmacology , vol.71 , Issue.2 , pp. 558-569
    • Chintharlapalli, S.1    Papineni, S.2    Safe, S.3
  • 49
    • 0020609015 scopus 로고
    • Pre-treatment and post-treatment evaluation of prostatic adenocarcinoma for prostatic specific acid phosphatase and prostatic specific antigen by immunohistochemistry
    • Vernon SE, Williams WD,. Pre-treatment and post-treatment evaluation of prostatic adenocarcinoma for prostatic specific acid phosphatase and prostatic specific antigen by immunohistochemistry. J Urol 1983; 130 (1): 95-98. (Pubitemid 13026591)
    • (1983) Journal of Urology , vol.130 , Issue.1 , pp. 95-98
    • Vernon, S.E.1    Williams, W.D.2
  • 50
    • 0029858399 scopus 로고    scopus 로고
    • PSA as a marker for prostate cancer: A critical review
    • Duffy MJ,. PSA as a marker for prostate cancer: A critical review. Ann Clin Biochem 1996; 33 (Pt 6): 511-519. (Pubitemid 26397713)
    • (1996) Annals of Clinical Biochemistry , vol.33 , Issue.6 , pp. 511-519
    • Duffy, M.J.1
  • 53
    • 0028865036 scopus 로고
    • Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion
    • Webber MM, Waghray A, Bello D,. Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion. Clin Cancer Res 1995; 1 (10): 1089-1094.
    • (1995) Clin Cancer Res , vol.1 , Issue.10 , pp. 1089-1094
    • Webber, M.M.1    Waghray, A.2    Bello, D.3
  • 54
    • 0028048974 scopus 로고
    • Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease
    • Cohen P, Peehl DM, Graves HC, Rosenfeld RG,. Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. J Endocrinol 1994; 142 (3): 407-415. (Pubitemid 24285445)
    • (1994) Journal of Endocrinology , vol.142 , Issue.3 , pp. 407-415
    • Cohen, P.1    Peehl, D.M.2    Craves, H.C.B.3    Rosenfeld, R.C.4
  • 55
    • 33646138016 scopus 로고    scopus 로고
    • Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity
    • Pereira de Jesus-Tran K, Cote PL, Cantin L, Blanchet J, Labrie F, Breton R,. Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity. Protein Sci 2006; 15 (5): 987-999.
    • (2006) Protein Sci , vol.15 , Issue.5 , pp. 987-999
    • Pereira De Jesus-Tran, K.1    Cote, P.L.2    Cantin, L.3    Blanchet, J.4    Labrie, F.5    Breton, R.6
  • 57
    • 0025080011 scopus 로고
    • Competitive binding of 7-substituted-2,3-dichlorodibenzo-p-dioxins with human placental Ah receptor - A QSAR analysis
    • DOI 10.1016/0006-2952(90)90309-9
    • Golas CL, Prokipcak RD, Okey AB, Manchester DK, Safe S, Fujita T,. Competitive binding of 7-substituted-2,3-dichlorodibenzo-p-dioxins with human placental ah receptor-A QSAR analysis. Biochem Pharmacol 1990; 40 (4): 737-741. (Pubitemid 20246578)
    • (1990) Biochemical Pharmacology , vol.40 , Issue.4 , pp. 737-741
    • Golas, C.L.1    Prokipcak, R.D.2    Okey, A.B.3    Manchester, D.K.4    Safe, S.5    Fujita, T.6
  • 58
    • 0023232569 scopus 로고
    • Quantitative structure-activity relationships: Analysis of interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2-substituted analogues with rat, mouse, guinea pig, and hamster cytosolic receptor
    • Romkes M, Piskorska-Pliszczynska J, Keys B, Safe S, Fujita T,. Quantitative structure-activity relationships: Analysis of interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2-substituted analogues with rat, mouse, guinea pig, and hamster cytosolic receptor. Cancer Res 1987; 47 (19): 5108-5111. (Pubitemid 17146481)
    • (1987) Cancer Research , vol.47 , Issue.19 , pp. 5108-5111
    • Romkes, M.1    Piskorska-Pliszczynska, J.2    Keys, B.3    Safe, S.4    Fujita, T.5
  • 59
    • 0022258326 scopus 로고
    • Effects of substituents on the cytosolic receptor-binding avidities and aryl hydrocarbon hydroxylase induction potencies of 7-substituted 2,3-dichlorodibenzo-p-dioxins. A quantitative structure-activity relationship analysis
    • Denomme MA, Homonoko K, Fujita T, Sawyer T, Safe S,. Effects of substituents on the cytosolic receptor-binding avidities and aryl hydrocarbon hydroxylase induction potencies of 7-substituted 2,3-dichlorodibenzo-p-dioxins. A quantitative structure-activity relationship analysis. Mol Pharmacol 1985; 27 (6): 656-661. (Pubitemid 15010698)
    • (1985) Molecular Pharmacology , vol.27 , Issue.6 , pp. 656-661
    • Denomme, M.A.1    Homonoko, K.2    Fujita, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.