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Volumn 12, Issue 8, 2013, Pages 1629-1637

NF-kB2/p52 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variants

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BICALUTAMIDE; ENZALUTAMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SHORT HAIRPIN RNA; ANTIANDROGEN; DRUG DERIVATIVE; PHENYLTHIOHYDANTOIN;

EID: 84882274167     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0027     Document Type: Article
Times cited : (155)

References (22)
  • 3
    • 65649090203 scopus 로고    scopus 로고
    • Development of a second-generation antiandrogen for treatment of advanced prostate cancer
    • Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009;324:787-90.
    • (2009) Science , vol.324 , pp. 787-790
    • Tran, C.1    Ouk, S.2    Clegg, N.J.3    Chen, Y.4    Watson, P.A.5    Arora, V.6
  • 4
    • 84872534568 scopus 로고    scopus 로고
    • Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines
    • Li Y, Chan SC, Brand LJ, Hwang TH, Silverstein KA, Dehm SM. Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines. Cancer Res 2013;73: 483-9.
    • (2013) Cancer Res , vol.73 , pp. 483-489
    • Li, Y.1    Chan, S.C.2    Brand, L.J.3    Hwang, T.H.4    Silverstein, K.A.5    Dehm, S.M.6
  • 5
    • 77953859606 scopus 로고    scopus 로고
    • NF-kB as a critical link between inflammation and cancer
    • Karin M. NF-kB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol 2009;1:a000141.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Karin, M.1
  • 6
    • 0034745420 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
    • Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 2001;7:401-9.
    • (2001) Mol Cell , vol.7 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.C.3
  • 7
    • 3142663912 scopus 로고    scopus 로고
    • Induction of p100 processing by NF-kappaBinducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation
    • Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaBinducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. J Biol Chem 2004; 279:30099-105.
    • (2004) J Biol Chem , vol.279 , pp. 30099-30105
    • Xiao, G.1    Fong, A.2    Sun, S.C.3
  • 8
    • 15444372287 scopus 로고    scopus 로고
    • Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100
    • Qing G, Xiao G. Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100. J Biol Chem 2005;280: 9765-8.
    • (2005) J Biol Chem , vol.280 , pp. 9765-9768
    • Qing, G.1    Xiao, G.2
  • 9
    • 12844275943 scopus 로고    scopus 로고
    • Regulation of NF-kappa B2 p100 processing by its cis-acting domain
    • Qing G, Qu Z, Xiao G. Regulation of NF-kappa B2 p100 processing by its cis-acting domain. J Biol Chem 2005;280:18-27.
    • (2005) J Biol Chem , vol.280 , pp. 18-27
    • Qing, G.1    Qu, Z.2    Xiao, G.3
  • 10
    • 33745852665 scopus 로고    scopus 로고
    • Alternative pathways of NF-kappaB activation: A double-edged sword in health and disease
    • Xiao G, Rabson AB, Young W, Qing G, Qu Z. Alternative pathways of NF-kappaB activation: A double-edged sword in health and disease. Cytokine Growth Factor Rev 2006;17:281-93.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 281-293
    • Xiao, G.1    Rabson, A.B.2    Young, W.3    Qing, G.4    Qu, Z.5
  • 11
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3
    • Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS Jr. Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene 2000;19:1123-31.
    • (2000) Oncogene , vol.19 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3    Baldwin Jr., A.S.4
  • 12
    • 33749504485 scopus 로고    scopus 로고
    • Nuclear localization of nuclear factorkappaB p65 in primary prostate tumors is highly predictive of pelvic lymph node metastases
    • Lessard L, Karakiewicz PI, Bellon-Gagnon P, Alam-Fahmy M, Ismail HA, Mes-Masson AM, et al. Nuclear localization of nuclear factorkappaB p65 in primary prostate tumors is highly predictive of pelvic lymph node metastases. Clin Cancer Res 2006;12:5741-5.
    • (2006) Clin Cancer Res , vol.12 , pp. 5741-5745
    • Lessard, L.1    Karakiewicz, P.I.2    Bellon-Gagnon, P.3    Alam-Fahmy, M.4    Ismail, H.A.5    Mes-Masson, A.M.6
  • 13
    • 56049083009 scopus 로고    scopus 로고
    • NF-kB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgendeprivation
    • Nadiminty N, Chun JY, Lou W, Lin X, Gao AC. NF-kB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgendeprivation. Prostate 2008;68:1725-33.
    • (2008) Prostate , vol.68 , pp. 1725-1733
    • Nadiminty, N.1    Chun, J.Y.2    Lou, W.3    Lin, X.4    Gao, A.C.5
  • 14
    • 75649120392 scopus 로고    scopus 로고
    • Microarray analysis reveals potential target genes of NF-k2/p52 in LNCaP prostate cancer cells
    • Nadiminty N, Dutt S, Tepper C, Gao AC. Microarray analysis reveals potential target genes of NF-k2/p52 in LNCaP prostate cancer cells. Prostate 2010;70:276-87.
    • (2010) Prostate , vol.70 , pp. 276-287
    • Nadiminty, N.1    Dutt, S.2    Tepper, C.3    Gao, A.C.4
  • 15
    • 77951036849 scopus 로고    scopus 로고
    • Aberrant activation of the androgen receptor by NF-kB2/p52 in prostate cancer cells
    • Nadiminty N, Lou W, Sun M, Chen J, Yue J, Kung HJ, et al. Aberrant activation of the androgen receptor by NF-kB2/p52 in prostate cancer cells. Cancer Res 2010;70:3309-19.
    • (2010) Cancer Res , vol.70 , pp. 3309-3319
    • Nadiminty, N.1    Lou, W.2    Sun, M.3    Chen, J.4    Yue, J.5    Kung, H.J.6
  • 16
    • 33646591224 scopus 로고    scopus 로고
    • Stat3 activation of NF-kappaB p100 processing involves CBP/p300-mediated acetylation
    • Nadiminty N, Lou W, Lee SO, Lin X, Trump DL, Gao AC. Stat3 activation of NF-kappaB p100 processing involves CBP/p300-mediated acetylation. Proc Natl Acad Sci USA 2006;103:7264-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7264-7269
    • Nadiminty, N.1    Lou, W.2    Lee, S.O.3    Lin, X.4    Trump, D.L.5    Gao, A.C.6
  • 17
    • 48549089747 scopus 로고    scopus 로고
    • Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
    • Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008;68:5469-77.
    • (2008) Cancer Res , vol.68 , pp. 5469-5477
    • Dehm, S.M.1    Schmidt, L.J.2    Heemers, H.V.3    Vessella, R.L.4    Tindall, D.J.5
  • 18
    • 80052827038 scopus 로고    scopus 로고
    • Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
    • Mostaghel EA, Marck BT, Plymate SR, Vessella RL, Balk S, Matsumoto AM, et al. Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res 2011;17:5913-25.
    • (2011) Clin Cancer Res , vol.17 , pp. 5913-5925
    • Mostaghel, E.A.1    Marck, B.T.2    Plymate, S.R.3    Vessella, R.L.4    Balk, S.5    Matsumoto, A.M.6
  • 19
    • 79955719838 scopus 로고    scopus 로고
    • Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival
    • Hornberg E, Ylitalo EB, Crnalic S, Antti H, Stattin P, Widmark A, et al. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival. PLoS One 2011;6:e19059.
    • (2011) PLoS One , vol.6
    • Hornberg, E.1    Ylitalo, E.B.2    Crnalic, S.3    Antti, H.4    Stattin, P.5    Widmark, A.6
  • 20
    • 58249110391 scopus 로고    scopus 로고
    • Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
    • Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 2009;69:16-22.
    • (2009) Cancer Res , vol.69 , pp. 16-22
    • Hu, R.1    Dunn, T.A.2    Wei, S.3    Isharwal, S.4    Veltri, R.W.5    Humphreys, E.6
  • 21
    • 78049280194 scopus 로고    scopus 로고
    • Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require fulllength androgen receptor
    • Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, et al. Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require fulllength androgen receptor. Proc Natl Acad Sci U S A 2010;107: 16759-65.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 16759-1665
    • Watson, P.A.1    Chen, Y.F.2    Balbas, M.D.3    Wongvipat, J.4    Socci, N.D.5    Viale, A.6
  • 22
    • 84863979005 scopus 로고    scopus 로고
    • Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
    • Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, et al. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res 2012;72: 3457-62.
    • (2012) Cancer Res , vol.72 , pp. 3457-3462
    • Hu, R.1    Lu, C.2    Mostaghel, E.A.3    Yegnasubramanian, S.4    Gurel, M.5    Tannahill, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.