Dynamic changes in the secondary structure of ECE-1 and XCE account for their different substrate specificities

BMC Bioinformatics

Volumn 13, Issue 1, 2012, Pages

  Ul Haq, Zaheer ^a   Iqbal, Sadaf ^a   Moin, Syed T ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE RESIDUES; CARBOXYLATE GROUPS; COMPLEX STRUCTURE; DIFFERENT SUBSTRATES; DYNAMIC CHANGES; DYNAMIC NATURE; EXPERIMENTAL DATUM; HOMOLOGY MODELS; MOLECULAR DYNAMICS SIMULATIONS; NATURAL SUBSTRATES; NON-CONSERVED RESIDUES; PHOSPHATE OXYGEN; SECONDARY STRUCTURES; SHEET STRUCTURE; SIMULATION TIME; STRONG BINDING; STRUCTURAL DIFFERENCES; SUBSTRATE SPECIFICITY; WATER MOLECULE;

CARBOXYLATION; ENZYMES; MOLECULAR DYNAMICS; ZINC;

SUBSTRATES;

ASPARTIC PROTEINASE; ECEL1 PROTEIN, HUMAN; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN-CONVERTING ENZYME; GLYCOPEPTIDE; METALLOPROTEINASE; PHOSPHORAMIDON;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; HUMAN; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ASPARTIC ACID ENDOPEPTIDASES; BINDING SITES; CATALYTIC DOMAIN; GLYCOPEPTIDES; HUMANS; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY;

MLCS; MLOWN;

EID: 84868250804     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-285     Document Type: Article

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