메뉴 건너뛰기




Volumn 11, Issue 10, 2013, Pages 1159-1165

Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; ONCOSTATIN M; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; STAT3 PROTEIN;

EID: 84886389273     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-13-0238     Document Type: Article
Times cited : (46)

References (20)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 70449526643 scopus 로고    scopus 로고
    • Chronic bacterial inflammation induces prostatic intraepithelial neoplasia in mouse prostate
    • Elkahwaji JE, Hauke RJ, Brawner CM. Chronic bacterial inflammation induces prostatic intraepithelial neoplasia in mouse prostate. Br J Cancer 2009;101:1740-8.
    • (2009) Br J Cancer , vol.101 , pp. 1740-1748
    • Elkahwaji, J.E.1    Hauke, R.J.2    Brawner, C.M.3
  • 5
    • 0346656567 scopus 로고    scopus 로고
    • Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate
    • Royuela M, Ricote M, Parsons MS, García-Tuñon I, Paniagua R, De Miguel MP. Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate. J Pathol 2004;202:41-9.
    • (2004) J Pathol , vol.202 , pp. 41-49
    • Royuela, M.1    Ricote, M.2    Parsons, M.S.3    García-Tuñon, I.4    Paniagua, R.5    De Miguel, M.P.6
  • 7
    • 0032880248 scopus 로고    scopus 로고
    • Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer
    • Drachenberg DE, Elgamal AA, RowbothamR, Peterson M, Murphy GP. Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer. Prostate 1999;41:127-33.
    • (1999) Prostate , vol.41 , pp. 127-133
    • Drachenberg, D.E.1    Elgamal, A.A.2    Rowbotham, R.3    Peterson, M.4    Murphy, G.P.5
  • 8
    • 0032830265 scopus 로고    scopus 로고
    • Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma
    • Adler HL, McCurdy MA, Kattan MW, Timme TL, Scardino PT, Thompson TC. Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma. J Urol 1999;161:182-7.
    • (1999) J Urol , vol.161 , pp. 182-187
    • Adler, H.L.1    McCurdy, M.A.2    Kattan, M.W.3    Timme, T.L.4    Scardino, P.T.5    Thompson, T.C.6
  • 9
    • 23944441266 scopus 로고    scopus 로고
    • Interleukin-6 regulation of prostate cancer cell growth
    • Culig Z, Steiner H, Bartsch G, Hobisch A. Interleukin-6 regulation of prostate cancer cell growth. J Cell Biochem 2005;95:497- 505.
    • (2005) J Cell Biochem , vol.95 , pp. 497-505
    • Culig, Z.1    Steiner, H.2    Bartsch, G.3    Hobisch, A.4
  • 10
    • 0035992415 scopus 로고    scopus 로고
    • Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells
    • Godoy-Tundidor S, Hobisch A, Pfeil K, Bartsch G, Culig Z. Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells. Clin Cancer Res 2002;8: 2356-61.
    • (2002) Clin Cancer Res , vol.8 , pp. 2356-2361
    • Godoy-Tundidor, S.1    Hobisch, A.2    Pfeil, K.3    Bartsch, G.4    Culig, Z.5
  • 11
    • 33645514605 scopus 로고    scopus 로고
    • Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice
    • Wallner L, Dai J, Escara-Wilke J, Zhang J, Yao Z, Lu Y, et al. Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res 2006;66:3087-95.
    • (2006) Cancer Res , vol.66 , pp. 3087-3095
    • Wallner, L.1    Dai, J.2    Escara-Wilke, J.3    Zhang, J.4    Yao, Z.5    Lu, Y.6
  • 12
    • 83255176682 scopus 로고    scopus 로고
    • Randomised phase II study of siltuximab (CNTO 328), an anti- IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer
    • Fizazi K, De Bono JS, Flechon A, Heidenreich A, Voog E, Davis NB, et al. Randomised phase II study of siltuximab (CNTO 328), an anti- IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer. Eur J Cancer 2012;48:85-93.
    • (2012) Eur J Cancer , vol.48 , pp. 85-93
    • Fizazi, K.1    De Bono, J.S.2    Flechon, A.3    Heidenreich, A.4    Voog, E.5    Davis, N.B.6
  • 13
    • 77954069855 scopus 로고    scopus 로고
    • Isolation, cultivation and characterization of adult murine prostate stem cells
    • Lukacs RU, Goldstein AS, Lawson DA, Cheng D, Witte ON. Isolation, cultivation and characterization of adult murine prostate stem cells. Nat Protoc 2010;5:702-13.
    • (2010) Nat Protoc , vol.5 , pp. 702-713
    • Lukacs, R.U.1    Goldstein, A.S.2    Lawson, D.A.3    Cheng, D.4    Witte, O.N.5
  • 15
    • 79956126860 scopus 로고    scopus 로고
    • IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR
    • Rojas A, Liu G, Coleman I, Nelson PS, Zhang M, Dash R, et al. IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR. Oncogene 2011;30:2345-55.
    • (2011) Oncogene , vol.30 , pp. 2345-2355
    • Rojas, A.1    Liu, G.2    Coleman, I.3    Nelson, P.S.4    Zhang, M.5    Dash, R.6
  • 16
    • 81155132204 scopus 로고    scopus 로고
    • C-MYC functions as a molecular switch to alter the response of human mammary epithelial cells to oncostatin M
    • Kan CE, Cipriano R, Jackson MW. c-MYC functions as a molecular switch to alter the response of human mammary epithelial cells to oncostatin M. Cancer Res 2011;71:6930-9.
    • (2011) Cancer Res , vol.71 , pp. 6930-6939
    • Kan, C.E.1    Cipriano, R.2    Jackson, M.W.3
  • 17
    • 0034721080 scopus 로고    scopus 로고
    • Oncostatin M and interleukin 6 inhibit cell cycle progression by prevention of p27kip1 degradation in HepG2 cells
    • Klausen P, Pedersen L, Jurlander J, Baumann H. Oncostatin M and interleukin 6 inhibit cell cycle progression by prevention of p27kip1 degradation in HepG2 cells. Oncogene 2000;19:3675-83.
    • (2000) Oncogene , vol.19 , pp. 3675-3683
    • Klausen, P.1    Pedersen, L.2    Jurlander, J.3    Baumann, H.4
  • 18
    • 33645920300 scopus 로고    scopus 로고
    • PI3K/Akt signaling regulates p27kip1 expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27kip1 regulation in LNCaP and PC346 cells
    • Van Duijn PW, Trapman J. PI3K/Akt signaling regulates p27kip1 expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27kip1 regulation in LNCaP and PC346 cells. Prostate 2006;66:749-60.
    • (2006) Prostate , vol.66 , pp. 749-760
    • Van Duijn, P.W.1    Trapman, J.2
  • 19
    • 0036847690 scopus 로고    scopus 로고
    • Elevated Skp2 protein expression in human prostate cancer association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival
    • Yang G, Ayala G, Marzo AD, Tian W, Frolov A, Wheeler TM, et al. Elevated Skp2 protein expression in human prostate cancer association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. Clin Cancer Res 2002; 8:3419-26.
    • (2002) Clin Cancer Res , vol.8 , pp. 3419-3426
    • Yang, G.1    Ayala, G.2    Marzo, A.D.3    Tian, W.4    Frolov, A.5    Wheeler, T.M.6
  • 20
    • 84255199166 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer: Emerging appreciation of genetic complexity
    • Barbieri CE, Demichelis F, Rubin MA. Molecular genetics of prostate cancer: emerging appreciation of genetic complexity. Histopathology 2012;60:187-98.
    • (2012) Histopathology , vol.60 , pp. 187-198
    • Barbieri, C.E.1    Demichelis, F.2    Rubin, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.