메뉴 건너뛰기




Volumn 74, Issue 2, 2014, Pages 609-620

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; FIBROBLAST GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR; WNT PROTEIN;

EID: 84892908353     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1093     Document Type: Article
Times cited : (35)

References (47)
  • 1
    • 0037337599 scopus 로고    scopus 로고
    • Fibroblast growth factors and their receptors in urological cancers: Basic research and clinical implications
    • Cronauer M, Schulz W, Seifert H-H, Ackermann R, Burchardt M. Fibroblast growth factors and their receptors in urological cancers: basic research and clinical implications. Eur Urol 2003;43:309-19.
    • (2003) Eur Urol , vol.43 , pp. 309-319
    • Cronauer, M.1    Schulz, W.2    Seifert, H.-H.3    Ackermann, R.4    Burchardt, M.5
  • 3
    • 79953072084 scopus 로고    scopus 로고
    • FGF signaling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting e-cadherin expression
    • Hardy KM, Yatskievych TA, Konieczka JH, Bobbs AS, Antin PB. FGF signaling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting e-cadherin expression. Dev Biol 2011;11:20.
    • (2011) Dev Biol , vol.11 , pp. 20
    • Hardy, K.M.1    Yatskievych, T.A.2    Konieczka, J.H.3    Bobbs, A.S.4    Antin, P.B.5
  • 4
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse R. Wnt signaling in disease and in development. Cell Res 2005;15:28-32.
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 6
    • 74649083953 scopus 로고    scopus 로고
    • Association analysis of wnt pathway genes on prostate-specific antigen recurrence after radical prostatectomy
    • Huang S, Ting W, Chen L, Huang L, Liu C. Association analysis of wnt pathway genes on prostate-specific antigen recurrence after radical prostatectomy. Ann Surg Oncol 2010;17:312-22.
    • (2010) Ann Surg Oncol , vol.17 , pp. 312-322
    • Huang, S.1    Ting, W.2    Chen, L.3    Huang, L.4    Liu, C.5
  • 7
    • 2442514340 scopus 로고    scopus 로고
    • Interactions between sox9 and beta-catenin control chondrocyte differentiation
    • Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, et al. Interactions between sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 2004;18:1072-87.
    • (2004) Genes Dev , vol.18 , pp. 1072-1087
    • Akiyama, H.1    Lyons, J.P.2    Mori-Akiyama, Y.3    Yang, X.4    Zhang, R.5    Zhang, Z.6
  • 8
    • 84855389100 scopus 로고    scopus 로고
    • Mesenchymal stromal cell mutations and wound healing contribute to the etiology of desmoid tumors
    • Carothers AM, Rizvi H, Hasson RM, Heit YI, Davids JS, Bertagnolli MM, et al. Mesenchymal stromal cell mutations and wound healing contribute to the etiology of desmoid tumors. Cancer Res 2012;72:346-55.
    • (2012) Cancer Res , vol.72 , pp. 346-355
    • Carothers, A.M.1    Rizvi, H.2    Hasson, R.M.3    Heit, Y.I.4    Davids, J.S.5    Bertagnolli, M.M.6
  • 9
    • 0037129305 scopus 로고    scopus 로고
    • In vitro evidence for complex modes of nuclear β-catenin signaling during prostate growth and tumorigenesis
    • Chesire DR, Ewing CM, Gage WR, Isaacs WB. In vitro evidence for complex modes of nuclear β-catenin signaling during prostate growth and tumorigenesis. Oncogene 2002;21:2679-94.
    • (2002) Oncogene , vol.21 , pp. 2679-2694
    • Chesire, D.R.1    Ewing, C.M.2    Gage, W.R.3    Isaacs, W.B.4
  • 10
    • 58249105729 scopus 로고    scopus 로고
    • K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse
    • Pearson HB, Phesse TJ, Clarke AR. K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse. Cancer Res 2009;69:94-101.
    • (2009) Cancer Res , vol.69 , pp. 94-101
    • Pearson, H.B.1    Phesse, T.J.2    Clarke, A.R.3
  • 11
    • 13644269949 scopus 로고    scopus 로고
    • Wnt signalling and the mechanistic basis of tumour development
    • Ilyas M. Wnt signalling and the mechanistic basis of tumour development. J Pathol 2005;205:130-44.
    • (2005) J Pathol , vol.205 , pp. 130-144
    • Ilyas, M.1
  • 12
    • 0035408007 scopus 로고    scopus 로고
    • Mesoderm cell fate specification and morphogenetic movement at the primitive streak
    • Ciruna B, Rossant J. Mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell 2001;1:37-49.
    • (2001) Dev Cell , vol.1 , pp. 37-49
    • Ciruna, B.1    Rossant, J.2
  • 13
    • 17844392598 scopus 로고    scopus 로고
    • A novel isoform of vinexin, vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad
    • Matsuyama M, Mizusaki H, Shimono A, Mukai T, Okumura K, Abe K, et al. A novel isoform of vinexin, vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad. Genes Cells 2005;10:421-34.
    • (2005) Genes Cells , vol.10 , pp. 421-434
    • Matsuyama, M.1    Mizusaki, H.2    Shimono, A.3    Mukai, T.4    Okumura, K.5    Abe, K.6
  • 14
    • 0041923688 scopus 로고    scopus 로고
    • Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest
    • Mori-Akiyama Y, Akiyama H, Rowitch DH, De Crombrugghe B. Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Proc Natl Acad Sci U S A 2003;100:9360-5.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9360-9365
    • Mori-Akiyama, Y.1    Akiyama, H.2    Rowitch, D.H.3    De Crombrugghe, B.4
  • 15
    • 77953732983 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer
    • Pond AC, Herschkowitz JI, Schwertfeger KL, Welm B, Zhang Y, York B, et al. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res 2010;70:4868-79.
    • (2010) Cancer Res , vol.70 , pp. 4868-4879
    • Pond, A.C.1    Herschkowitz, J.I.2    Schwertfeger, K.L.3    Welm, B.4    Zhang, Y.5    York, B.6
  • 16
    • 84863230264 scopus 로고    scopus 로고
    • Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling
    • Horst D, Chen J, Morikawa T, Ogino S, Kirchner T, Shivdasani RA. Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res 2012;72:1547-56.
    • (2012) Cancer Res , vol.72 , pp. 1547-1556
    • Horst, D.1    Chen, J.2    Morikawa, T.3    Ogino, S.4    Kirchner, T.5    Shivdasani, R.A.6
  • 17
    • 36649025928 scopus 로고    scopus 로고
    • Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition
    • Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, et al. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell 2007;12:559-71.
    • (2007) Cancer Cell , vol.12 , pp. 559-571
    • Acevedo, V.D.1    Gangula, R.D.2    Freeman, K.W.3    Li, R.4    Zhang, Y.5    Wang, F.6
  • 18
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012;2:401-4.
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3    Gross, B.E.4    Sumer, S.O.5    Aksoy, B.A.6
  • 19
    • 43949145269 scopus 로고    scopus 로고
    • Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis
    • Dell'accio F, De Bari C, Eltawil NM, Vanhummelen P, Pitzalis C. Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis. Arthritis Rheum 2008;58:1410-21.
    • (2008) Arthritis Rheum , vol.58 , pp. 1410-1421
    • Dell'accio, F.1    De Bari, C.2    Eltawil, N.M.3    Vanhummelen, P.4    Pitzalis, C.5
  • 20
    • 0347722250 scopus 로고    scopus 로고
    • Growth factors regulate β-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing
    • Cheon SS, Nadesan P, Poon R, Alman BA. Growth factors regulate β-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing. Exp Cell Res 2004;293:267-74.
    • (2004) Exp Cell Res , vol.293 , pp. 267-274
    • Cheon, S.S.1    Nadesan, P.2    Poon, R.3    Alman, B.A.4
  • 21
    • 34249292278 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration
    • Yokoyama H, Ogino H, Stoick-Cooper CL, Grainger RM, Moon RT. Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration. Dev Biol 2007;306:170-8.
    • (2007) Dev Biol , vol.306 , pp. 170-178
    • Yokoyama, H.1    Ogino, H.2    Stoick-Cooper, C.L.3    Grainger, R.M.4    Moon, R.T.5
  • 22
    • 41149142238 scopus 로고    scopus 로고
    • Requirement for Wnt and FGF signaling in xenopus tadpole tail regeneration
    • Lin G, Slack J M W. Requirement for Wnt and FGF signaling in xenopus tadpole tail regeneration. Dev Biol 2008;316:323-35.
    • (2008) Dev Biol , vol.316 , pp. 323-335
    • Lin, G.1    Slack, J.M.W.2
  • 23
    • 55349084792 scopus 로고    scopus 로고
    • Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression
    • Aman A, Piotrowski T. Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression. Dev Cell 2008;15:749-61.
    • (2008) Dev Cell , vol.15 , pp. 749-761
    • Aman, A.1    Piotrowski, T.2
  • 24
    • 84868633053 scopus 로고    scopus 로고
    • Treatment-induced damage to the tumor micro-environment promotes prostate cancer therapy resistance through WNT16B
    • Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, et al. Treatment-induced damage to the tumor micro-environment promotes prostate cancer therapy resistance through WNT16B. Nat Med 2012;18:1359-68.
    • (2012) Nat Med , vol.18 , pp. 1359-1368
    • Sun, Y.1    Campisi, J.2    Higano, C.3    Beer, T.M.4    Porter, P.5    Coleman, I.6
  • 25
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • Zhang J, Thomas TZ, Kasper S, Matusik RJ. A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology 2000;141:4698-710.
    • (2000) Endocrinology , vol.141 , pp. 4698-4710
    • Zhang, J.1    Thomas, T.Z.2    Kasper, S.3    Matusik, R.J.4
  • 26
    • 0345734275 scopus 로고    scopus 로고
    • Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice
    • Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, et al. Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res 2003;63:8256-63.
    • (2003) Cancer Res , vol.63 , pp. 8256-8263
    • Freeman, K.W.1    Welm, B.E.2    Gangula, R.D.3    Rosen, J.M.4    Ittmann, M.5    Greenberg, N.M.6
  • 27
    • 0141885098 scopus 로고    scopus 로고
    • Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation
    • Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, et al. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. Cancer Res 2003;63:6237-43.
    • (2003) Cancer Res , vol.63 , pp. 6237-6243
    • Freeman, K.W.1    Gangula, R.D.2    Welm, B.E.3    Ozen, M.4    Foster, B.A.5    Rosen, J.M.6
  • 28
    • 84856401425 scopus 로고    scopus 로고
    • Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis
    • Shahi P, Park D, Pond AC, Seethammagari M, Chiou S-H, Cho K, et al. Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS ONE 2012;7:e30814.
    • (2012) PLoS ONE , vol.7
    • Shahi, P.1    Park, D.2    Pond, A.C.3    Seethammagari, M.4    Chiou, S.-H.5    Cho, K.6
  • 29
    • 78149461997 scopus 로고    scopus 로고
    • TGF-β1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse
    • Barron DA, Strand DW, Ressler SJ, Dang TD, Hayward SW, Yang F, et al. TGF-β1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse. PLoS ONE 2010;5:e13751.
    • (2010) PLoS ONE , vol.5
    • Barron, D.A.1    Strand, D.W.2    Ressler, S.J.3    Dang, T.D.4    Hayward, S.W.5    Yang, F.6
  • 30
    • 0036718369 scopus 로고    scopus 로고
    • Reactive stroma in human prostate cancer: Induction of myofibroblast phenotype and extracellular matrix remodeling
    • Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clinical Cancer Res 2002;9:2912-23.
    • (2002) Clinical Cancer Res , vol.9 , pp. 2912-2923
    • Tuxhorn, J.A.1    Ayala, G.E.2    Smith, M.J.3    Smith, V.C.4    Dang, T.D.5    Rowley, D.R.6
  • 31
    • 36249006969 scopus 로고    scopus 로고
    • Self-renewal and multilineage differentiation in vitro from murine prostate stem cells
    • Xin L, Lukacs RU, Lawson DA, Cheng D, Witte ON. Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells 2007;25:2760-9.
    • (2007) Stem Cells , vol.25 , pp. 2760-2769
    • Xin, L.1    Lukacs, R.U.2    Lawson, D.A.3    Cheng, D.4    Witte, O.N.5
  • 32
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview-extensible visualization of microarray data
    • Saldanha AJ. Java Treeview-extensible visualization of microarray data. Bioinformatics 2004;20:3246-8.
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 33
    • 84877785851 scopus 로고    scopus 로고
    • Animal models of human prostate cancer: The consensus report of the New York meeting of the mouse models of human cancers consortium prostate pathology committee
    • Ittmann M, Huang J, Radaelli E, Martin P, Signoretti S, Sullivan R, et al. Animal models of human prostate cancer: the consensus report of the New York meeting of the mouse models of human cancers consortium prostate pathology committee. Cancer Res 2013;73:2718-36.
    • (2013) Cancer Res , vol.73 , pp. 2718-2736
    • Ittmann, M.1    Huang, J.2    Radaelli, E.3    Martin, P.4    Signoretti, S.5    Sullivan, R.6
  • 34
    • 84859827014 scopus 로고    scopus 로고
    • Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/ osteolytic bone lesions
    • Li X, Sterling JA, Fan K-H, Vessella RL, Shyr Y, Hayward SW, et al. Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions. Mol Cancer Res 2012;10:494-503.
    • (2012) Mol Cancer Res , vol.10 , pp. 494-503
    • Li, X.1    Sterling, J.A.2    Fan, K.-H.3    Vessella, R.L.4    Shyr, Y.5    Hayward, S.W.6
  • 36
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang DW, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009;37:1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 37
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009;4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 38
    • 79960154778 scopus 로고    scopus 로고
    • Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development
    • Yin Y, Wang F, Ornitz DM. Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development. Development 2011;138:3169-77.
    • (2011) Development , vol.138 , pp. 3169-3177
    • Yin, Y.1    Wang, F.2    Ornitz, D.M.3
  • 39
    • 78449263437 scopus 로고    scopus 로고
    • Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice
    • Elo TD, Valve EM. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice. Neoplasia 2010;12:915-27.
    • (2010) Neoplasia , vol.12 , pp. 915-927
    • Elo, T.D.1    Valve, E.M.2
  • 40
    • 84863011082 scopus 로고    scopus 로고
    • Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells
    • Wan X, Liu J, Lu J-F, Tzelepi V, Yang J, Starbuck MW, et al. Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells. Clin Cancer Res 2012;18:726-36.
    • (2012) Clin Cancer Res , vol.18 , pp. 726-736
    • Wan, X.1    Liu, J.2    Lu, J.-F.3    Tzelepi, V.4    Yang, J.5    Starbuck, M.W.6
  • 42
    • 79951842547 scopus 로고    scopus 로고
    • Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis
    • Franco OE, Jiang M, Strand DW, Peacock J, Fernandez S, Jackson RS, et al. Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. Cancer Res 2011;71:1272-81.
    • (2011) Cancer Res , vol.71 , pp. 1272-1281
    • Franco, O.E.1    Jiang, M.2    Strand, D.W.3    Peacock, J.4    Fernandez, S.5    Jackson, R.S.6
  • 43
    • 0842288323 scopus 로고    scopus 로고
    • TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Neilson EG, Moses HL. TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004;303:848-851.
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Neilson, E.G.3    Moses, H.L.4
  • 44
    • 60549100868 scopus 로고    scopus 로고
    • Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-βeta signaling
    • Li X, Wang Y, Sharif-Afshar A-R, Uwamariya C, Yi A, Ishii K, et al. Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-βeta signaling. Differentiation 2009;77:95-102.
    • (2009) Differentiation , vol.77 , pp. 95-102
    • Li, X.1    Wang, Y.2    Sharif-Afshar, A.-R.3    Uwamariya, C.4    Yi, A.5    Ishii, K.6
  • 46
    • 84859416889 scopus 로고    scopus 로고
    • Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells
    • Mulholland DJ, Kobayashi N, Ruscetti M, Zhi A, Tran LM, Huang J, et al. Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res 2012;72:1878-89.
    • (2012) Cancer Res , vol.72 , pp. 1878-1889
    • Mulholland, D.J.1    Kobayashi, N.2    Ruscetti, M.3    Zhi, A.4    Tran, L.M.5    Huang, J.6
  • 47
    • 79251512318 scopus 로고    scopus 로고
    • Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens
    • Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, et al. Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens. Am J Pathol 2011;178:79-87.
    • (2011) Am J Pathol , vol.178 , pp. 79-87
    • Ayala, G.E.1    Muezzinoglu, B.2    Hammerich, K.H.3    Frolov, A.4    Liu, H.5    Scardino, P.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.