메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

The role of IL-6 in the radiation response of prostate cancer

Author keywords

IL 6; Irradiation; Prostate cancer

Indexed keywords

INTERLEUKIN 6; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN;

EID: 84880697448     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-8-159     Document Type: Article
Times cited : (111)

References (40)
  • 2
    • 51349111250 scopus 로고    scopus 로고
    • Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
    • 2518074, 18725989
    • Kinkade CW, Castillo-Martin M, Puzio-Kuter A, et al. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest 2008, 118:3051-3064. 2518074, 18725989.
    • (2008) J Clin Invest , vol.118 , pp. 3051-3064
    • Kinkade, C.W.1    Castillo-Martin, M.2    Puzio-Kuter, A.3
  • 3
    • 4544384318 scopus 로고    scopus 로고
    • Radiation oncology: a century of achievements
    • Bernier J, Hall EJ, Giaccia A. Radiation oncology: a century of achievements. Nat Rev Cancer 2004, 4(9):737-747.
    • (2004) Nat Rev Cancer , vol.4 , Issue.9 , pp. 737-747
    • Bernier, J.1    Hall, E.J.2    Giaccia, A.3
  • 4
    • 33947536682 scopus 로고    scopus 로고
    • Responses of normal cells to ionizing radiation
    • 10.1016/j.semradonc.2006.11.005, 17395038
    • Rodemann HP, Blaese MA. Responses of normal cells to ionizing radiation. Semin Radiat Oncol 2007, 17(2):81-88. 10.1016/j.semradonc.2006.11.005, 17395038.
    • (2007) Semin Radiat Oncol , vol.17 , Issue.2 , pp. 81-88
    • Rodemann, H.P.1    Blaese, M.A.2
  • 5
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • 10.1016/j.cell.2010.01.025, 2866629, 20303878
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899. 10.1016/j.cell.2010.01.025, 2866629, 20303878.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 6
    • 78049441629 scopus 로고    scopus 로고
    • Targeting inflammatory pathways for tumor radiosensitization
    • 10.1016/j.bcp.2010.06.039, 3090731, 20599771
    • Deorukhkar A, Krishnan S. Targeting inflammatory pathways for tumor radiosensitization. Biochem Pharmacol 2010, 80(12):1904-1914. 10.1016/j.bcp.2010.06.039, 3090731, 20599771.
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 1904-1914
    • Deorukhkar, A.1    Krishnan, S.2
  • 7
    • 17644368573 scopus 로고    scopus 로고
    • Interleukin-6: from basic science to medicine-40 years in immunology
    • 10.1146/annurev.immunol.23.021704.115806, 15771564
    • Kishimoto T. Interleukin-6: from basic science to medicine-40 years in immunology. Annu Rev Immunol 2005, 23:1-21. 10.1146/annurev.immunol.23.021704.115806, 15771564.
    • (2005) Annu Rev Immunol , vol.23 , pp. 1-21
    • Kishimoto, T.1
  • 8
    • 65549130575 scopus 로고    scopus 로고
    • Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor
    • Malinowska K, Neuwirt H, Cavarretta IT, et al. Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. Endocr Relat Cancer 2009, 16:155-169.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 155-169
    • Malinowska, K.1    Neuwirt, H.2    Cavarretta, I.T.3
  • 9
    • 69949140389 scopus 로고    scopus 로고
    • Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma
    • 10.1016/j.radonc.2009.06.022, 19616333
    • Bonner JA, Trummell HQ, Willey CD, Plants BA, Raisch KP. Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma. Radiother Oncol 2009, 92(3):339-344. 10.1016/j.radonc.2009.06.022, 19616333.
    • (2009) Radiother Oncol , vol.92 , Issue.3 , pp. 339-344
    • Bonner, J.A.1    Trummell, H.Q.2    Willey, C.D.3    Plants, B.A.4    Raisch, K.P.5
  • 10
    • 35648995976 scopus 로고    scopus 로고
    • Interleukin-6 and its receptor in cancer: implications for translational therapeutics
    • 10.1002/cncr.22999, 17849470
    • Hong DS, Angelo LS, Kurzrock R. Interleukin-6 and its receptor in cancer: implications for translational therapeutics. Cancer 2007, 110(9):1911-1928. 10.1002/cncr.22999, 17849470.
    • (2007) Cancer , vol.110 , Issue.9 , pp. 1911-1928
    • Hong, D.S.1    Angelo, L.S.2    Kurzrock, R.3
  • 11
    • 36849017497 scopus 로고    scopus 로고
    • IL-6 involvement in epithelial cancers
    • 10.1172/JCI34237, 2096452, 18060028
    • Schafer ZT, Brugge JS. IL-6 involvement in epithelial cancers. J Clin Invest 2007, 117(12):3660-3663. 10.1172/JCI34237, 2096452, 18060028.
    • (2007) J Clin Invest , vol.117 , Issue.12 , pp. 3660-3663
    • Schafer, Z.T.1    Brugge, J.S.2
  • 12
    • 84864017887 scopus 로고    scopus 로고
    • Interleukin-6: a multifunctional targetable cytokine in human prostate cancer
    • 3409376, 21664423
    • Culig Z, Puhr M. Interleukin-6: a multifunctional targetable cytokine in human prostate cancer. Mol Cell Endocrinol 2012, 360(1-2):52-58. 3409376, 21664423.
    • (2012) Mol Cell Endocrinol , vol.360 , Issue.1-2 , pp. 52-58
    • Culig, Z.1    Puhr, M.2
  • 13
    • 84865422083 scopus 로고    scopus 로고
    • Interleukin-6 signaling pathway in targeted therapy for cancer
    • 10.1016/j.ctrv.2012.04.007, 22651903
    • Guo Y, Xu F, Lu T, Duan Z, Zhang Z. Interleukin-6 signaling pathway in targeted therapy for cancer. Cancer Treat Rev 2012, 38(7):904-910. 10.1016/j.ctrv.2012.04.007, 22651903.
    • (2012) Cancer Treat Rev , vol.38 , Issue.7 , pp. 904-910
    • Guo, Y.1    Xu, F.2    Lu, T.3    Duan, Z.4    Zhang, Z.5
  • 14
    • 0028203595 scopus 로고
    • Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer
    • 10.1002/1097-0142(19940401)73:7<1882::AID-CNCR2820730718>3.0.CO;2-R, 8137215
    • Plante M, Rubin SC, Wong GY, Federici MG, Finstad CL, Gastl GA. Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. Cancer 1994, 73(7):1882-1888. 10.1002/1097-0142(19940401)73:7<1882::AID-CNCR2820730718>3.0.CO;2-R, 8137215.
    • (1994) Cancer , vol.73 , Issue.7 , pp. 1882-1888
    • Plante, M.1    Rubin, S.C.2    Wong, G.Y.3    Federici, M.G.4    Finstad, C.L.5    Gastl, G.A.6
  • 15
    • 0033036097 scopus 로고    scopus 로고
    • Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma
    • Zhang GJ, Adachi I. Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res 1999, 19(2B):1427-1432.
    • (1999) Anticancer Res , vol.19 , Issue.2 B , pp. 1427-1432
    • Zhang, G.J.1    Adachi, I.2
  • 16
    • 84875821295 scopus 로고    scopus 로고
    • IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus
    • 10.1186/1476-4598-12-26, 3667147, 23561329
    • Chen MF, Chen PT, Lu MS, Lin PY, Chen WC, Lee KD. IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus. Mol Cancer 2013, 12(1):26. 10.1186/1476-4598-12-26, 3667147, 23561329.
    • (2013) Mol Cancer , vol.12 , Issue.1 , pp. 26
    • Chen, M.F.1    Chen, P.T.2    Lu, M.S.3    Lin, P.Y.4    Chen, W.C.5    Lee, K.D.6
  • 17
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 10.1038/nri2506, 2828349, 19197294
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009, 9(3):162-174. 10.1038/nri2506, 2828349, 19197294.
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 18
    • 77955019652 scopus 로고    scopus 로고
    • Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation
    • 10.1158/0008-5472.CAN-09-4446, 2918387, 20631066
    • Kozin SV, Kamoun WS, Huang Y, Dawson MR, Jain RK, Duda DG. Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation. Cancer Res 2010, 70(14):5679-5685. 10.1158/0008-5472.CAN-09-4446, 2918387, 20631066.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5679-5685
    • Kozin, S.V.1    Kamoun, W.S.2    Huang, Y.3    Dawson, M.R.4    Jain, R.K.5    Duda, D.G.6
  • 19
    • 84868125342 scopus 로고    scopus 로고
    • Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells
    • Wu CT, Hsieh CC, Lin CC, Chen WC, Hong JH, Chen MF. Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells. J Mol Med (Berl) 2012, 90(11):1343-1355.
    • (2012) J Mol Med (Berl) , vol.90 , Issue.11 , pp. 1343-1355
    • Wu, C.T.1    Hsieh, C.C.2    Lin, C.C.3    Chen, W.C.4    Hong, J.H.5    Chen, M.F.6
  • 20
    • 77956410126 scopus 로고    scopus 로고
    • Role of DNA methyltransferase 1 in hormone-resistant prostate cancer
    • Chen MF, Chen WC, Chang YJ, Wu CF, Wu CT. Role of DNA methyltransferase 1 in hormone-resistant prostate cancer. J Mol Med (Berl) 2010, 88(9):953-962.
    • (2010) J Mol Med (Berl) , vol.88 , Issue.9 , pp. 953-962
    • Chen, M.F.1    Chen, W.C.2    Chang, Y.J.3    Wu, C.F.4    Wu, C.T.5
  • 21
    • 35948985191 scopus 로고    scopus 로고
    • The radiation response of hormone-resistant prostate cancer induced by long-term hormone therapy
    • 10.1677/ERC-07-0073, 17914094
    • Wu CT, Chen WC, Liao SK, Hsu CL, Lee KD, Chen MF. The radiation response of hormone-resistant prostate cancer induced by long-term hormone therapy. Endocr Relat Cancer 2007, 14(3):633-643. 10.1677/ERC-07-0073, 17914094.
    • (2007) Endocr Relat Cancer , vol.14 , Issue.3 , pp. 633-643
    • Wu, C.T.1    Chen, W.C.2    Liao, S.K.3    Hsu, C.L.4    Lee, K.D.5    Chen, M.F.6
  • 22
    • 84869104326 scopus 로고    scopus 로고
    • Role of interleukin-6 in the radiation response of liver tumors
    • 10.1016/j.ijrobp.2012.07.2360, 22975618
    • Chen MF, Hsieh CC, Chen WC, Lai CH. Role of interleukin-6 in the radiation response of liver tumors. Int J Radiat Oncol Biol Phys 2012, 84(5):e621-e630. 10.1016/j.ijrobp.2012.07.2360, 22975618.
    • (2012) Int J Radiat Oncol Biol Phys , vol.84 , Issue.5
    • Chen, M.F.1    Hsieh, C.C.2    Chen, W.C.3    Lai, C.H.4
  • 23
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • 2575748, 18832739
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008, 181(8):5791-5802. 2575748, 18832739.
    • (2008) J Immunol , vol.181 , Issue.8 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 24
    • 59849126377 scopus 로고    scopus 로고
    • Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
    • Li H, Han Y, Guo Q, Zhang M, Cao X. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol 2009, 182(1):240-249.
    • (2009) J Immunol , vol.182 , Issue.1 , pp. 240-249
    • Li, H.1    Han, Y.2    Guo, Q.3    Zhang, M.4    Cao, X.5
  • 25
    • 0037718255 scopus 로고    scopus 로고
    • Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
    • 10.1016/S0006-2952(03)00083-2, 12754093
    • Myhre O, Andersen JM, Aarnes H, Fonnum F. Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation. Biochem Pharmacol 2003, 65(10):1575-1582. 10.1016/S0006-2952(03)00083-2, 12754093.
    • (2003) Biochem Pharmacol , vol.65 , Issue.10 , pp. 1575-1582
    • Myhre, O.1    Andersen, J.M.2    Aarnes, H.3    Fonnum, F.4
  • 26
    • 18244396940 scopus 로고    scopus 로고
    • Morphology of angiogenesis in human cancer: a conceptual overview, histoprognostic perspective and significance of neoangiogenesis
    • 10.1111/j.1365-2559.2005.02142.x, 15842629
    • Sharma S, Sharma MC, Sarkar C. Morphology of angiogenesis in human cancer: a conceptual overview, histoprognostic perspective and significance of neoangiogenesis. Histopathology 2005, 46(5):481-489. 10.1111/j.1365-2559.2005.02142.x, 15842629.
    • (2005) Histopathology , vol.46 , Issue.5 , pp. 481-489
    • Sharma, S.1    Sharma, M.C.2    Sarkar, C.3
  • 27
    • 0038199578 scopus 로고    scopus 로고
    • Persistent oxidative stress after ionizing radiation is involved in inherited radiosensitivity
    • 10.1016/S0891-5849(03)00243-0, 12826257
    • Tulard A, Hoffschir F, de Boisferon FH, Luccioni C, Bravard A. Persistent oxidative stress after ionizing radiation is involved in inherited radiosensitivity. Free Radic Biol Med 2003, 35(1):68-77. 10.1016/S0891-5849(03)00243-0, 12826257.
    • (2003) Free Radic Biol Med , vol.35 , Issue.1 , pp. 68-77
    • Tulard, A.1    Hoffschir, F.2    de Boisferon, F.H.3    Luccioni, C.4    Bravard, A.5
  • 28
    • 33645514605 scopus 로고    scopus 로고
    • Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice
    • 10.1158/0008-5472.CAN-05-3447, 16540658
    • Wallner L, Dai J, Escara-Wilke J, et al. Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res 2006, 66:3087-3095. 10.1158/0008-5472.CAN-05-3447, 16540658.
    • (2006) Cancer Res , vol.66 , pp. 3087-3095
    • Wallner, L.1    Dai, J.2    Escara-Wilke, J.3
  • 29
    • 83255176682 scopus 로고    scopus 로고
    • Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer
    • Fizazi K, De Bono JS, Flechon A, et al. Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer. Eur J Cancer 2012, 48:85-93.
    • (2012) Eur J Cancer , vol.48 , pp. 85-93
    • Fizazi, K.1    De Bono, J.S.2    Flechon, A.3
  • 30
    • 0142250392 scopus 로고    scopus 로고
    • Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence
    • 2929399, 14581334
    • Trikha M, Corringham R, Klein B, Rossi JF. Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003, 9(13):4653-4665. 2929399, 14581334.
    • (2003) Clin Cancer Res , vol.9 , Issue.13 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 31
    • 0344441877 scopus 로고    scopus 로고
    • Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways
    • 10.1038/sj.onc.1207084, 14586407
    • Leu CM, Wong FH, Chang C, Huang SF, Hu CP. Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. Oncogene 2003, 22(49):7809-7818. 10.1038/sj.onc.1207084, 14586407.
    • (2003) Oncogene , vol.22 , Issue.49 , pp. 7809-7818
    • Leu, C.M.1    Wong, F.H.2    Chang, C.3    Huang, S.F.4    Hu, C.P.5
  • 32
    • 0034003395 scopus 로고    scopus 로고
    • Sensing and responding to DNA damage
    • 10.1016/S0959-437X(99)00050-7, 10679395
    • Lowndes NF, Murguia JR. Sensing and responding to DNA damage. Curr Opin Genet Dev 2000, 10(1):17-25. 10.1016/S0959-437X(99)00050-7, 10679395.
    • (2000) Curr Opin Genet Dev , vol.10 , Issue.1 , pp. 17-25
    • Lowndes, N.F.1    Murguia, J.R.2
  • 33
    • 4344577088 scopus 로고    scopus 로고
    • Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents
    • 10.1158/0008-5472.CAN-04-0494, 15342409
    • Achanta G, Huang P. Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents. Cancer Res 2004, 64(17):6233-6239. 10.1158/0008-5472.CAN-04-0494, 15342409.
    • (2004) Cancer Res , vol.64 , Issue.17 , pp. 6233-6239
    • Achanta, G.1    Huang, P.2
  • 34
    • 0028960967 scopus 로고    scopus 로고
    • Androgen suppressed apoptosis is modified in p53 deficient mice
    • Colombel M, Radvanyi F, Blanche M, et al. Androgen suppressed apoptosis is modified in p53 deficient mice. Oncogene 1999, 10:1269-1274.
    • (1999) Oncogene , vol.10 , pp. 1269-1274
    • Colombel, M.1    Radvanyi, F.2    Blanche, M.3
  • 35
    • 0035450742 scopus 로고    scopus 로고
    • Reduction of wild type p53 function confers a hormone resistant phenotype on LNCaP prostate cancer cells
    • 10.1002/pros.1101, 11536301
    • Burchardt M, Burchardt T, Shabsigh A, et al. Reduction of wild type p53 function confers a hormone resistant phenotype on LNCaP prostate cancer cells. Prostate 2001, 48:225-230. 10.1002/pros.1101, 11536301.
    • (2001) Prostate , vol.48 , pp. 225-230
    • Burchardt, M.1    Burchardt, T.2    Shabsigh, A.3
  • 36
    • 23844503025 scopus 로고    scopus 로고
    • Role of Stat3 in regulating p53 expression and function
    • 10.1128/MCB.25.17.7432-7440.2005, 1190305, 16107692
    • Niu G, Wright KL, Ma Y, et al. Role of Stat3 in regulating p53 expression and function. Mol Cell Biol 2005, 25(17):7432-7440. 10.1128/MCB.25.17.7432-7440.2005, 1190305, 16107692.
    • (2005) Mol Cell Biol , vol.25 , Issue.17 , pp. 7432-7440
    • Niu, G.1    Wright, K.L.2    Ma, Y.3
  • 37
    • 84864483190 scopus 로고    scopus 로고
    • Molecular pathways: involving microenvironment damage responses in cancer therapy resistance
    • 10.1158/1078-0432.CCR-11-0768, 22619305
    • Sun Y, Nelson PS. Molecular pathways: involving microenvironment damage responses in cancer therapy resistance. Clin Cancer Res 2012, 18(15):4019-4025. 10.1158/1078-0432.CCR-11-0768, 22619305.
    • (2012) Clin Cancer Res , vol.18 , Issue.15 , pp. 4019-4025
    • Sun, Y.1    Nelson, P.S.2
  • 38
    • 1842668004 scopus 로고    scopus 로고
    • Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells
    • Lee SO, Lou W, Hou M, de Miguel F, Gerber L, Gao AC. Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells. Clin Cancer Res 2003, 9(1):370-376.
    • (2003) Clin Cancer Res , vol.9 , Issue.1 , pp. 370-376
    • Lee, S.O.1    Lou, W.2    Hou, M.3    de Miguel, F.4    Gerber, L.5    Gao, A.C.6
  • 39
    • 1942517751 scopus 로고    scopus 로고
    • An autocrine loop for vascular endothelial growth factor is established in prostate cancer cells generated after prolonged treatment with interleukin 6
    • 10.1016/j.ejca.2003.11.033, 15093584
    • Steiner H, Berger AP, Godoy-Tundidor S, et al. An autocrine loop for vascular endothelial growth factor is established in prostate cancer cells generated after prolonged treatment with interleukin 6. Eur J Cancer 2004, 40(7):1066-1072. 10.1016/j.ejca.2003.11.033, 15093584.
    • (2004) Eur J Cancer , vol.40 , Issue.7 , pp. 1066-1072
    • Steiner, H.1    Berger, A.P.2    Godoy-Tundidor, S.3
  • 40
    • 5444225991 scopus 로고    scopus 로고
    • Expansion of myeloid immune suppressor Gr + CD11b + cells in tumor-bearing host directly promotes tumor angiogenesis
    • 10.1016/j.ccr.2004.08.031, 15488763
    • Yang L, DeBusk LM, Fukuda K, et al. Expansion of myeloid immune suppressor Gr + CD11b + cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004, 6(4):409-421. 10.1016/j.ccr.2004.08.031, 15488763.
    • (2004) Cancer Cell , vol.6 , Issue.4 , pp. 409-421
    • Yang, L.1    DeBusk, L.M.2    Fukuda, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.