Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Salvatori, Luisa ^a,b   Caporuscio, Francesca ^b,c   Verdina, Alessandra ^b   Starace, Giuseppe ^b   Crispi, Stefania ^d   Nicotra, Maria Rita ^a   Russo, Andrea ^b   Calogero, Raffaele Adolfo ^e   Morgante, Emanuela ^c   Natali, Pier Giorgio ^f   Russo, Matteo Antonio ^c,g   Petrangeli, Elisa ^a,b,c  

^a CNR   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^e Molecular Biotechnology Center   (Italy)

^f UNIVERSITY OF CHIETI   (Italy)

^g IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BULKING AGENT; UVOMORULIN; VIMENTIN; CADHERIN; CD24 ANTIGEN; HERMES ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INFILTRATION; CANCER PROGNOSIS; CANCER STEM CELL; CELL COMMUNICATION; CELL DENSITY; CELL DIFFERENTIATION; CELL FATE; CELL LINE; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN DU145; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NEUROSECRETORY CELL; NONHUMAN; PHENOTYPE; PROSTATE CANCER; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT; ANIMAL; DNA MICROARRAY; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; TUMOR CELL LINE; XENOGRAFT;

MUS MUSCULUS;

ANIMALS; ANTIGENS, CD24; ANTIGENS, CD44; BETA CATENIN; CADHERINS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; MALE; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84856645746     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031467     Document Type: Article

References (47)

1. Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics. CA Cancer J Clin 60: 277-300.
2. Feldman BJ, Feldman D, (2001) The development of androgen-independent prostate cancer. Nat Rev Cancer 1: 34-45.
3. Bonkhoff H, Stein U, Remberger K, (1993) Androgen receptor status in endocrine-paracrine cell types of the normal, hyperplastic and neoplastic human prostate. Virchows Arch A Pathol Anat Histopathol 423: 291-294.
4. Debes JD, Tindall DJ, (2004) Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351: 1488-1490.
5. Abrahamsson PA, Di Sant'Agnese PA, (1993) Neuroendocrine cells in the human prostate gland. J Androl 14: 307-309.
6. Abrahamsson PA, (1999) Neuroendocrine cells in tumor growth of the prostate. Endocr Relat Cancer 6: 503-519.
7. Hoosein NM, Logothetis CJ, Chung LW, (1993) Differential effects of peptide hormones bombesin, vasoactive intestinal polypeptide and somatostatin analog RC-160 on the invasive capacity of human prostatic carcinoma cells. J Urol 149: 1209-1213.
8. Grobholz R, Griebe M, Sauer CG, Michel MS, Trojan L, et al. (2005) Influence of neuroendocrine tumor cells on proliferation in prostatic carcinoma. Hum Pathol 36: 562-570.
9. Kamiya N, Suzuki H, Kawamura K, Imamoto T, Naya Y, et al. (2008) Neuroendocrine differentiation in stage D2 prostate cancers. Int J Urol 15: 423-428.
10. Huss WJ, Gray DR, Werdin ES, Funkhouser WK Jr, Smith GJ, (2004) Evidence of pluripotent human prostate stem cells in a human prostate primary xenograft model. Prostate 60: 77-90.
11. Damsky CH, Richa J, Solter D, Knudsen K, Buck CA, (1983) Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. Cell 34: 455-466.
12. Takeichi M, (1991) Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251: 1451-1455.
13. Hinck L, Nelson WJ, Papkoff J, (1994) Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin. J Cell Biol 124: 729-741.
14. Vleminckx K, Vakaet L Jr, Mareel M, Fiers W, van Roy F, (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66: 107-119.
15. Umbas R, Isaacs WB, Bringuier PP, Schaafsma HE, Karthaus HFM, et al. (1994) Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer. Cancer Res 54: 3929-3933.
16. De Marzo AM, Knudsen B, Chan-Tack K, Epstein JI, (1999) E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens. Urology 53: 707-713.
17. Lang SH, Hyde C, Reid IN, Hitchcock IS, Hart CA, et al. (2002) Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma. Prostate 52: 253-263.
18. Reya T, Morrison SJ, Clarke MF, Weissman IL, (2001) Stem cells, cancer, and cancer stem cells. Nature 414: 105-111.
19. Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ, (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65: 10946-10951.
20. Hurt EM, Kawasaki BT, Klarmann GJ, Thomas SB, Farrar WL, (2008) CD44+CD24- prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Brit J Cancer 98: 756-765.
21. Rius C, Aller P, (1992) Vimentin expression as a late event in the in vitro differentiation of human promonocytic cells. J Cell Sci 101: 395-401.
22. Kessel RG, (1992) Annulate lamellae: a last frontier in cellular organelles. Int Rev Cytol 133: 43-120.
23. Bae KM, Su Z, Frye C, McClellan S, Allan RW, et al. (2010) Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells. J Urol 183: 2045-2053.
24. Redmer T, Diecke S, Grigoryan T, Quiroga-Negreira A, Birchmeier W, et al. (2011) E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming. EMBO reports 12: 720-726.
25. Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, et al. (2006) Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25: 1696-1708.
26. Nicholson B, Theodorescu D, (2004) Angiogenesis and prostate cancer tumor growth. J Cell Biochem 91: 125-150.
27. Morita N, Uemura H, Tsumatani K, Cho M, Hirao Y, et al. (1999) E-cadherin and alpha-, beta- and gamma-catenin expression in prostate cancers: correlation with tumour invasion. Brit J Cancer 79: 1879-1883.
28. Nagakawa O, Murakami K, Ogasawara M, Murata J, Fuse H, et al. (1999) Effect of chromogranin A (pancreastatin) fragment on invasion of prostate cancer cells. Cancer Lett 147: 207-213.
29. Lind AJ, Wikstrom P, Granfors T, Egevad L, Stattin P, et al. (2005) Angiopoietin 2 expression is related to histological grade, vascular density, metastases and outcome in prostate cancer. Prostate 62: 394-399.
30. Sun ZJ, Wang Y, Cai Z, Chen PP, Tong XJ, et al. (2008) Involvement of Cyr61 in growth, migration, and metastasis of prostate cancer cells. Brit J Cancer 99: 1656-1667.
31. Jennbacken K, Vallbo C, Wang W, Damber JE, (2005) Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis. Prostate 65: 110-116.
32. Shiina H, Breault JE, Basset WW, Enokida H, Urakami S, et al. (2005) Functional loss of the gamma-catenin gene through epigenetic and genetic pathways in human prostate cancer. Cancer Res 65: 2130-2138.
33. Pontes-Junior J, Reis ST, Dall'Oglio M, Neves de Oliveira LC, Cury J, et al. (2009) Evaluation of the expression of integrins and cell adhesion molecules through tissue microarray in lymph node metastases of prostate cancer. J Carcinog 8: 1-7.
34. Orlichenko L, Weller SG, Cao H, Krueger EW, Awoniyi M, et al. (2009) Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation. Mol Biol Cell 20: 4140-4152.
35. Liu B, Lee KW, Anzo M, Zhang B, Zi X, et al. (2007) Insulin-like growth factor-binding protein-3 inhibition of prostate cancer growth involves suppression of angiogenesis. Oncogene 26: 1811-1819.
36. Hanai J, Mammoto T, Seth P, Mori K, Karumanchi SA, et al. (2005) Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells. J Biol Chem 280: 13641-13647.
37. Wesley UV, McGroarty M, Homoyouni A, (2005) Dipeptidyl peptidase inhibits malignant phenotype of prostate cancer cells by blocking basic fibroblast growth factor signaling pathway. Cancer Res 65: 1325-1334.
38. Wang J, Place RF, Huang V, Wang X, Noonan EJ, et al. (2010) Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res 70: 10182-10191.
39. Han SH, Jeon JH, Ju HR, Jung U, Kim KY, et al. (2003) VDUP1 upregulated by TGF-beta1 and 1,25-dihydroxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression. Oncogene 22: 4035-4046.
40. Walker MR, Patel KK, Stappenbeck TS, (2009) The stem cell niche. J Pathol 217: 169-180.
41. Ravenna L, Di Silverio F, Russo MA, Salvatori L, Morgante E, et al. (1996) Effects of the lipidosterolic extract of serenoa repens (Permixon®) on human prostatic cell lines. Prostate 29: 219-230.
42. Sanges R, Cordero F, Calogero RA, (2007) OneChannelGUI: a graphical interface to Bioconductor tools, designed for life scientists who are not familiar with R language. Bioinformatics 23: 3406-3408.
43. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264.
44. Bolstad BM, Irizarry RA, Astrand M, Speed TP, (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19: 185-193.
45. Smyth GK, (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3 3: Article3.
46. Westfall PH, Young SS, (1993) Resampling-based multiple testing: examples and materials and methods for P-value adjustment New York John Wiley & Sons.
47. Barrett T, Suzek TO, Troup DB, Wilhite SE, Ngau WC, et al. (2005) NCBI GEO: mining millions of expression profiles-database and tools. Nucleic Acids Res 33 (Database issue): D562-566.