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Volumn 8, Issue 12, 2013, Pages

Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD24 ANTIGEN; HERMES ANTIGEN; PROTEIN INHIBITOR; SHORT HAIRPIN RNA; STAT3 PROTEIN; ALDEHYDE DEHYDROGENASE ISOENZYME 1; ANTHRAQUINONE DERIVATIVE; ISOENZYME; LLL12 COMPOUND; MOLECULAR LIBRARY; RETINAL DEHYDROGENASE; SMALL INTERFERING RNA; STATTIC; SULFONAMIDE; SULFOXIDE;

EID: 84893511414     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082821     Document Type: Article
Times cited : (59)

References (37)
  • 1
    • 7944235577 scopus 로고    scopus 로고
    • Diverse mechanisms regulate stem cell self-renewal
    • Molofsky A, Pardal R, Morrison S (2004) Diverse mechanisms regulate stem cell self-renewal. Curr Opin Cell Biol 16: 700-707.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 700-707
    • Molofsky, A.1    Pardal, R.2    Morrison, S.3
  • 2
    • 0141483064 scopus 로고    scopus 로고
    • Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
    • Passegue E, Jamieson C, Ailles L, Weissman I (2003) Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?. Proc Natl Acad Sci USA 100: 11842-11849.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11842-11849
    • Passegue, E.1    Jamieson, C.2    Ailles, L.3    Weissman, I.4
  • 4
    • 60549111070 scopus 로고    scopus 로고
    • Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
    • Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, et al. (2009) Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature. Cancer Res 69: 1302-1313.
    • (2009) Cancer Res , vol.69 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3    Wicinski, J.4    Cervera, N.5
  • 5
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, et al. (2007) ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome. Cell Stem Cell 1: 555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3    Monville, F.4    Dutcher, J.5
  • 6
    • 60149101077 scopus 로고    scopus 로고
    • ALDH1 as a Functional Marker of Cancer Stem and Progenitor Cells
    • Douville J, Beaulieu R, Balicki D (2009) ALDH1 as a Functional Marker of Cancer Stem and Progenitor Cells. Stem Cells Dev 18: 17-25.
    • (2009) Stem Cells Dev , vol.18 , pp. 17-25
    • Douville, J.1    Beaulieu, R.2    Balicki, D.3
  • 7
    • 35348893870 scopus 로고    scopus 로고
    • Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy
    • Germain D, Frank DA (2007) Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy. Clin Cancer Res 13: 5665-5669.
    • (2007) Clin Cancer Res , vol.13 , pp. 5665-5669
    • Germain, D.1    Frank, D.A.2
  • 8
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • Turkson J, Jove R (2002) STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 19: 6613-6626.
    • (2002) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 10
    • 25444454543 scopus 로고    scopus 로고
    • New and old functions of STAT3: A pivotal target for individualized treatment of cancer
    • Inghirami G, Chiarle R, Simmons WJ, Piva R, Schlessinger K, et al. (2005) New and old functions of STAT3: a pivotal target for individualized treatment of cancer. Cell Cycle 4: 1131-1133.
    • (2005) Cell Cycle , vol.4 , pp. 1131-1133
    • Inghirami, G.1    Chiarle, R.2    Simmons, W.J.3    Piva, R.4    Schlessinger, K.5
  • 11
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R (2002) Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8: 945-954.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 12
    • 0042415425 scopus 로고    scopus 로고
    • Role of the stromal microenvironment in carcinogenesis of the prostate
    • Cunha GR, Hayward SW, Wang YZ, Ricke WA (2003) Role of the stromal microenvironment in carcinogenesis of the prostate. Int J Cancer 107: 1-10.
    • (2003) Int J Cancer , vol.107 , pp. 1-10
    • Cunha, G.R.1    Hayward, S.W.2    Wang, Y.Z.3    Ricke, W.A.4
  • 13
    • 67449113764 scopus 로고    scopus 로고
    • Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers
    • Tanei T, Morimoto K, Shimazu K, Kim SJ, Tanji Y, et al. (2009) Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin Cancer Res 15: 4234-4241.
    • (2009) Clin Cancer Res , vol.15 , pp. 4234-4241
    • Tanei, T.1    Morimoto, K.2    Shimazu, K.3    Kim, S.J.4    Tanji, Y.5
  • 14
    • 33750982120 scopus 로고    scopus 로고
    • Stattic: A small-molecule inhibitor of STAT3 activation and dimerization
    • Schust J, Sperl B, Hollis A, Mayer TU, Berg T (2006) Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol 13: 1235-1242.
    • (2006) Chem Biol , vol.13 , pp. 1235-1242
    • Schust, J.1    Sperl, B.2    Hollis, A.3    Mayer, T.U.4    Berg, T.5
  • 15
    • 75149195336 scopus 로고    scopus 로고
    • The transcriptional network for mesenchymal transformation of brain tumours
    • Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, et al. (2010) The transcriptional network for mesenchymal transformation of brain tumours. nature 463: 318-325.
    • (2010) Nature , vol.463 , pp. 318-325
    • Carro, M.S.1    Lim, W.K.2    Alvarez, M.J.3    Bollo, R.J.4    Zhao, X.5
  • 16
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • Kaptein A, Paillard V, Saunders M (1996) Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J Biol Chem 271: 5961-5964.
    • (1996) J Biol Chem , vol.271 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 17
    • 73949111590 scopus 로고    scopus 로고
    • A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppresive Activity in Human Cancer Cells
    • Lin L, Hutzen B, Li PK, Ball S, Zuo M, et al. (2010) A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppresive Activity in Human Cancer Cells. Neoplasia 12: 39-50.
    • (2010) Neoplasia , vol.12 , pp. 39-50
    • Lin, L.1    Hutzen, B.2    Li, P.K.3    Ball, S.4    Zuo, M.5
  • 18
    • 37549062631 scopus 로고    scopus 로고
    • Design, synthesis, and studies of small molecule STAT3 inhibitors
    • Bhasin D, Cisek K, Pandharkar T, Regan N, Li C, et al. (2008) Design, synthesis, and studies of small molecule STAT3 inhibitors. Bioorg Med Chem Lett 18: 391-395.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 391-395
    • Bhasin, D.1    Cisek, K.2    Pandharkar, T.3    Regan, N.4    Li, C.5
  • 19
    • 31544458469 scopus 로고    scopus 로고
    • Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells
    • Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, et al. (2006) Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells. Clin Cancer Res 12: 11-19.
    • (2006) Clin Cancer Res , vol.12 , pp. 11-19
    • Gritsko, T.1    Williams, A.2    Turkson, J.3    Kaneko, S.4    Bowman, T.5
  • 20
    • 47249161129 scopus 로고    scopus 로고
    • Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
    • Cheng GZ, Zhang WZ, Sun M, Wang Q, Coppola D, et al. (2008) Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. J Biol Chem 283: 14665-14673.
    • (2008) J Biol Chem , vol.283 , pp. 14665-14673
    • Cheng, G.Z.1    Zhang, W.Z.2    Sun, M.3    Wang, Q.4    Coppola, D.5
  • 21
    • 35948981785 scopus 로고    scopus 로고
    • Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer
    • Landen CN Jr, Lin YG, Armaiz Pena GN, Das PD, Arevalo JM, et al. (2007) Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer. Cancer Res 67: 10389-10396.
    • (2007) Cancer Res , vol.67 , pp. 10389-10396
    • Landen Jr., C.N.1    Lin, Y.G.2    Armaiz Pena, G.N.3    Das, P.D.4    Arevalo, J.M.5
  • 22
    • 33645532055 scopus 로고    scopus 로고
    • Activation of stat3 in human melanoma promotes brain metastasis
    • Xie TX, Huang FJ, Aldape KD, Kang SH, Liu M, et al. (2006) Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res 66: 3188-3196.
    • (2006) Cancer Res , vol.66 , pp. 3188-3196
    • Xie, T.X.1    Huang, F.J.2    Aldape, K.D.3    Kang, S.H.4    Liu, M.5
  • 23
    • 37349098725 scopus 로고    scopus 로고
    • Autocrine IL-6 signaling: A key event in tumorigenesis?
    • Grivennikov S, Karin M (2008) Autocrine IL-6 signaling: a key event in tumorigenesis? Cancer Cell 13: 7-9.
    • (2008) Cancer Cell , vol.13 , pp. 7-9
    • Grivennikov, S.1    Karin, M.2
  • 25
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore CM, Kuperwasser C (2008) Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res 10: R25.
    • (2008) Breast Cancer Res , vol.10
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 26
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24 (2/low)/CD44+ breast cancer-initiating cells to radiation
    • Phillips TM, McBride WH, Pajonk F (2006) The response of CD24 (2/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 98: 1777-1785.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 27
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, et al. (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65: 5506-5511.
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3    Pratesi, G.4    Petrangolini, G.5
  • 28
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • Turkson J, Jove R (2000) STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 19: 6613-6626.
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 29
    • 70350212976 scopus 로고    scopus 로고
    • STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
    • Sherry MM, Reeves A, Wu JK, Cochran BH (2009) STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells. Stem Cells 27: 2383-2392.
    • (2009) Stem Cells , vol.27 , pp. 2383-2392
    • Sherry, M.M.1    Reeves, A.2    Wu, J.K.3    Cochran, B.H.4
  • 30
    • 70350223977 scopus 로고    scopus 로고
    • Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth
    • Wang H, Lathia JD, Wu Q, Wang J, Li Z, et al. (2009) Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth. Stem Cells 27: 2393-2404.
    • (2009) Stem Cells , vol.27 , pp. 2393-2404
    • Wang, H.1    Lathia, J.D.2    Wu, Q.3    Wang, J.4    Li, Z.5
  • 33
    • 78751522709 scopus 로고    scopus 로고
    • Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks
    • Liu S, Ginestier C, Ou SJ, Clouthier SG, Patel SH, et al. (2011) Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks. Cancer Res 15: 614-624.
    • (2011) Cancer Res , vol.15 , pp. 614-624
    • Liu, S.1    Ginestier, C.2    Ou, S.J.3    Clouthier, S.G.4    Patel, S.H.5
  • 34
    • 79959956046 scopus 로고    scopus 로고
    • The JAK/STAT3 signaling pathway is required for growth of CD44+CD24-stem cell-like breast cancer cells in human tumors
    • doi:44710.41172/JC144745
    • Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, et al. (2011) The JAK/STAT3 signaling pathway is required for growth of CD44+CD24-stem cell-like breast cancer cells in human tumors. J Clin Invest 121: 44745 doi:44710.41172/JC144745.
    • (2011) J Clin Invest , vol.121 , pp. 44745
    • Marotta, L.L.1    Almendro, V.2    Marusyk, A.3    Shipitsin, M.4    Schemme, J.5
  • 35
    • 84864673390 scopus 로고    scopus 로고
    • Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model
    • Dave B, Landis M, Tweardy D, Chang J, Dobrolecki L, et al. (2012) Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One 7: e30207.
    • (2012) PLoS One , vol.7
    • Dave, B.1    Landis, M.2    Tweardy, D.3    Chang, J.4    Dobrolecki, L.5
  • 36
    • 78649876801 scopus 로고    scopus 로고
    • STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy?
    • Villalva C, Martin-Lannerée S, Cortes U, Dkhissi F, Wager M, et al. (2010) STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy? Int J Cancer. 128: 826-838.
    • (2010) Int J Cancer , vol.128 , pp. 826-838
    • Villalva, C.1    Martin-Lannerée, S.2    Cortes, U.3    Dkhissi, F.4    Wager, M.5


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