메뉴 건너뛰기




Volumn 5 MAR, Issue , 2014, Pages

Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease

Author keywords

Cancer; Constraint based modeling; Human metabolism; Inborn errors of metabolism; Metabolic networks and pathways; Transport mechanisms

Indexed keywords

AMINO ACID TRANSPORTER; AQUAPORIN; ASCORBIC ACID; BETAINE; BIOTIN; CARNITINE; CARRIER PROTEIN; CHOLESTEROL; CYANOCOBALAMIN; FOLIC ACID; GLUCOSE TRANSPORTER; HEME; LIPOPROTEIN; NICOTINAMIDE; NUCLEOSIDE TRANSPORTER; PANTOTHENIC ACID; PYRIDOXINE; RIBOFLAVIN; SODIUM GLUCOSE COTRANSPORTER; TAURINE; THIAMINE; VITAMIN;

EID: 84897931922     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00091     Document Type: Review
Times cited : (77)

References (227)
  • 1
    • 0142244159 scopus 로고    scopus 로고
    • Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease
    • doi: 10.1152/ajpgi.00056.2003
    • Adibi, S. A. (2003). Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. Am. J. Physiol. Gastrointest. Liver Physiol. 285, G779-G788. doi: 10.1152/ajpgi.00056.2003.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.285
    • Adibi, S.A.1
  • 2
    • 84863662483 scopus 로고    scopus 로고
    • Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT
    • doi: 10.1371/journal.pcbi.1002518
    • Agren, R., Bordel, S., Mardinoglu, A., Pornputtapong, N., Nookaew, I., and Nielsen, J. (2012). Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PLoS Comput. Biol. 8:e1002518. doi: 10.1371/journal.pcbi.1002518.
    • (2012) PLoS Comput. Biol. , vol.8
    • Agren, R.1    Bordel, S.2    Mardinoglu, A.3    Pornputtapong, N.4    Nookaew, I.5    Nielsen, J.6
  • 3
    • 79958251737 scopus 로고    scopus 로고
    • Proton-coupled oligopeptide transporter (POT) family expression in human nasal epithelium and their drug transport potential
    • doi: 10.1021/mp100234z
    • Agu, R., Cowley, E., Shao, D., Macdonald, C., Kirkpatrick, D., Renton, K., et al. (2011). Proton-coupled oligopeptide transporter (POT) family expression in human nasal epithelium and their drug transport potential. Mol. Pharm. 8, 664-672. doi: 10.1021/mp100234z.
    • (2011) Mol. Pharm. , vol.8 , pp. 664-672
    • Agu, R.1    Cowley, E.2    Shao, D.3    Macdonald, C.4    Kirkpatrick, D.5    Renton, K.6
  • 5
    • 34347333381 scopus 로고    scopus 로고
    • Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis
    • doi: 10.1016/j.tips.2007.05.004
    • Amaral, M. D., and Kunzelmann, K. (2007). Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis. Trends Pharmacol. Sci. 28, 334-341. doi: 10.1016/j.tips.2007.05.004.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 334-341
    • Amaral, M.D.1    Kunzelmann, K.2
  • 6
    • 77949895746 scopus 로고    scopus 로고
    • Effect of carnitine and herbal mixture extract on obesity induced by high fat diet in rats
    • doi: 10.1186/1758-5996-1-17
    • Amin, K. A., and Nagy, M. A. (2009). Effect of carnitine and herbal mixture extract on obesity induced by high fat diet in rats. Diabetol. Metab. Syndr. 1, 17. doi: 10.1186/1758-5996-1-17.
    • (2009) Diabetol. Metab. Syndr. , vol.1 , pp. 17
    • Amin, K.A.1    Nagy, M.A.2
  • 9
    • 77953598589 scopus 로고    scopus 로고
    • The protein family of glucose transport facilitators: It's not only about glucose after all
    • doi: 10.1002/iub.315
    • Augustin, R. (2010). The protein family of glucose transport facilitators: It's not only about glucose after all. IUBMB Life 62, 315-333. doi: 10.1002/iub.315.
    • (2010) IUBMB Life , vol.62 , pp. 315-333
    • Augustin, R.1
  • 10
    • 33745953360 scopus 로고    scopus 로고
    • Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants
    • doi: 10.1124/jpet.106.104364
    • Badagnani, I., Castro, R. A., Taylor, T. R., Brett, C. M., Huang, C. C., Stryke, D., et al. (2006). Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J. Pharmacol. Exp. Ther. 318, 521-529. doi: 10.1124/jpet.106.104364.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 521-529
    • Badagnani, I.1    Castro, R.A.2    Taylor, T.R.3    Brett, C.M.4    Huang, C.C.5    Stryke, D.6
  • 11
    • 69049097269 scopus 로고    scopus 로고
    • Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes
    • doi: 10.1152/ajpendo.00330.2009
    • Baird, F. E., Bett, K. J., Maclean, C., Tee, A. R., Hundal, H. S., and Taylor, P. M. (2009). Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes. Am. J. Physiol. Endocrinol. Metab. 297, E822-E829. doi: 10.1152/ajpendo.00330.2009.
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Baird, F.E.1    Bett, K.J.2    Maclean, C.3    Tee, A.R.4    Hundal, H.S.5    Taylor, P.M.6
  • 12
    • 65549107435 scopus 로고    scopus 로고
    • Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues
    • doi: 10.1523/JNEUROSCI.0858-09.2009
    • Bakirtzi, K., Belfort, G., Lopez-Coviella, I., Kuruppu, D., Cao, L., Abel, E. D., et al. (2009). Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues. J. Neurosci. 29, 5193-5201. doi: 10.1523/JNEUROSCI.0858-09.2009.
    • (2009) J. Neurosci. , vol.29 , pp. 5193-5201
    • Bakirtzi, K.1    Belfort, G.2    Lopez-Coviella, I.3    Kuruppu, D.4    Cao, L.5    Abel, E.D.6
  • 13
    • 1242272722 scopus 로고    scopus 로고
    • The equilibrative nucleoside transporter family, SLC29
    • doi: 10.1007/s00424-003-1103-2
    • Baldwin, S. A., Beal, P. R., Yao, S. Y., King, A. E., Cass, C. E., and Young, J. D. (2004). The equilibrative nucleoside transporter family, SLC29. Pflugers Arch. 447, 735-743. doi: 10.1007/s00424-003-1103-2.
    • (2004) Pflugers Arch. , vol.447 , pp. 735-743
    • Baldwin, S.A.1    Beal, P.R.2    Yao, S.Y.3    King, A.E.4    Cass, C.E.5    Young, J.D.6
  • 15
    • 33748337923 scopus 로고    scopus 로고
    • Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH
    • doi: 10.1161/01.RES.0000238359.18495.42
    • Barnes, K., Dobrzynski, H., Foppolo, S., Beal, P. R., Ismat, F., Scullion, E. R., et al. (2006). Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH. Circ. Res. 99, 510-519. doi: 10.1161/01.RES.0000238359.18495.42.
    • (2006) Circ. Res. , vol.99 , pp. 510-519
    • Barnes, K.1    Dobrzynski, H.2    Foppolo, S.3    Beal, P.R.4    Ismat, F.5    Scullion, E.R.6
  • 16
    • 0031028236 scopus 로고    scopus 로고
    • Bioavailability of riboflavin
    • Bates, C. J. (1997). Bioavailability of riboflavin. Eur. J. Clin. Nutr. 51(Suppl. 1), S38-S42.
    • (1997) Eur. J. Clin. Nutr. , vol.51 , Issue.SUPPL. 1
    • Bates, C.J.1
  • 17
    • 79952734461 scopus 로고    scopus 로고
    • Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses
    • doi: 10.1073/pnas.1011115108
    • Berry, D. C., Jin, H., Majumdar, A., and Noy, N. (2011). Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses. Proc. Natl. Acad. Sci. U.S.A. 108, 4340-4345. doi: 10.1073/pnas.1011115108.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4340-4345
    • Berry, D.C.1    Jin, H.2    Majumdar, A.3    Noy, N.4
  • 18
    • 77956316182 scopus 로고    scopus 로고
    • A single amino acid change converts the sugar sensor SGLT3 into a sugar transporter
    • doi: 10.1371/journal.pone.0010241
    • Bianchi, L., and Diez-Sampedro, A. (2010). A single amino acid change converts the sugar sensor SGLT3 into a sugar transporter. PLoS ONE 5:e10241. doi: 10.1371/journal.pone.0010241.
    • (2010) PLoS ONE , vol.5
    • Bianchi, L.1    Diez-Sampedro, A.2
  • 20
    • 80054969621 scopus 로고    scopus 로고
    • A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology
    • doi: 10.1186/1752-0509-5-180
    • Bordbar, A., Feist, A. M., Usaite-Black, R., Woodcock, J., Palsson, B. O., and Famili, I. (2011a). A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology. BMC Syst. Biol. 5:180. doi: 10.1186/1752-0509-5-180.
    • (2011) BMC Syst. Biol. , vol.5 , pp. 180
    • Bordbar, A.1    Feist, A.M.2    Usaite-Black, R.3    Woodcock, J.4    Palsson, B.O.5    Famili, I.6
  • 21
    • 79960169210 scopus 로고    scopus 로고
    • iAB-RBC-283: a proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states
    • doi: 10.1186/1752-0509-5-110
    • Bordbar, A., Jamshidi, N., and Palsson, B. O. (2011b). iAB-RBC-283: a proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states. BMC Syst. Biol. 5:110. doi: 10.1186/1752-0509-5-110.
    • (2011) BMC Syst. Biol. , vol.5 , pp. 110
    • Bordbar, A.1    Jamshidi, N.2    Palsson, B.O.3
  • 22
    • 77958537509 scopus 로고    scopus 로고
    • Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions
    • doi: 10.1038/msb.2010.68
    • Bordbar, A., Lewis, N. E., Schellenberger, J., Palsson, B. O., and Jamshidi, N. (2010). Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions. Mol. Syst. Biol. 6, 422. doi: 10.1038/msb.2010.68.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 422
    • Bordbar, A.1    Lewis, N.E.2    Schellenberger, J.3    Palsson, B.O.4    Jamshidi, N.5
  • 23
    • 22144441741 scopus 로고    scopus 로고
    • Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells
    • doi: 10.1016/j.bbrc.2005.06.069
    • Boyer, J. C., Campbell, C. E., Sigurdson, W. J., and Kuo, S. M. (2005). Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells. Biochem. Biophys. Res. Commun. 334, 150-156. doi: 10.1016/j.bbrc.2005.06.069.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 150-156
    • Boyer, J.C.1    Campbell, C.E.2    Sigurdson, W.J.3    Kuo, S.M.4
  • 24
    • 38349170961 scopus 로고    scopus 로고
    • Amino acid transport across mammalian intestinal and renal epithelia
    • doi: 10.1152/physrev.00018.2006
    • Broer, S. (2008). Amino acid transport across mammalian intestinal and renal epithelia. Physiol. Rev. 88, 249-286. doi: 10.1152/physrev.00018.2006.
    • (2008) Physiol. Rev. , vol.88 , pp. 249-286
    • Broer, S.1
  • 25
    • 79956041076 scopus 로고    scopus 로고
    • The role of amino acid transporters in inherited and acquired diseases
    • doi: 10.1042/BJ20101912
    • Broer, S., and Palacin, M. (2011). The role of amino acid transporters in inherited and acquired diseases. Biochem. J. 436, 193-211. doi: 10.1042/BJ20101912.
    • (2011) Biochem. J. , vol.436 , pp. 193-211
    • Broer, S.1    Palacin, M.2
  • 27
    • 80051709984 scopus 로고    scopus 로고
    • Allelic and phenotypic heterogeneity in ABCA4 mutations
    • doi: 10.3109/13816810.2011.565397
    • Burke, T. R., and Tsang, S. H. (2011). Allelic and phenotypic heterogeneity in ABCA4 mutations. Ophthalmic Genet. 32, 165-174. doi: 10.3109/13816810.2011.565397.
    • (2011) Ophthalmic Genet. , vol.32 , pp. 165-174
    • Burke, T.R.1    Tsang, S.H.2
  • 28
    • 79251517382 scopus 로고    scopus 로고
    • Regulation of cancer cell metabolism
    • doi: 10.1038/nrc2981
    • Cairns, R. A., Harris, I. S., and Mak, T. W. (2011). Regulation of cancer cell metabolism. Nat. Rev. Cancer 11, 85-95. doi: 10.1038/nrc2981.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 85-95
    • Cairns, R.A.1    Harris, I.S.2    Mak, T.W.3
  • 29
    • 79952216550 scopus 로고    scopus 로고
    • Potential role of sugar transporters in cancer and their relationship with anticancer therapy
    • doi: 10.1155/2010/205357
    • Calvo, M. B., Figueroa, A., Pulido, E. G., Campelo, R. G., and Aparicio, L. A. (2010). Potential role of sugar transporters in cancer and their relationship with anticancer therapy. Int. J. Endocrinol. 2010:205357. doi: 10.1155/2010/205357.
    • (2010) Int. J. Endocrinol. , vol.2010 , pp. 205357
    • Calvo, M.B.1    Figueroa, A.2    Pulido, E.G.3    Campelo, R.G.4    Aparicio, L.A.5
  • 31
    • 36749103888 scopus 로고    scopus 로고
    • Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane
    • doi: 10.1016/j.plefa.2007.10.017
    • Chabowski, A., Gorski, J., Luiken, J. J., Glatz, J. F., and Bonen, A. (2007). Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane. Prostaglandins Leukot. Essent. Fatty Acids 77, 345-353. doi: 10.1016/j.plefa.2007.10.017.
    • (2007) Prostaglandins Leukot. Essent. Fatty Acids , vol.77 , pp. 345-353
    • Chabowski, A.1    Gorski, J.2    Luiken, J.J.3    Glatz, J.F.4    Bonen, A.5
  • 32
    • 78049445175 scopus 로고    scopus 로고
    • Drug off-target effects predicted using structural analysis in the context of a metabolic network model
    • doi: 10.1371/journal.pcbi.1000938
    • Chang, R. L., Xie, L., Bourne, P. E., and Palsson, B. O. (2010). Drug off-target effects predicted using structural analysis in the context of a metabolic network model. PLoS Comput. Biol. 6:e1000938. doi: 10.1371/journal.pcbi.1000938.
    • (2010) PLoS Comput. Biol. , vol.6
    • Chang, R.L.1    Xie, L.2    Bourne, P.E.3    Palsson, B.O.4
  • 33
    • 33646858115 scopus 로고    scopus 로고
    • The oligopeptide transporter hPepT1: gateway to the innate immune response
    • doi: 10.1038/labinvest.3700423
    • Charrier, L., and Merlin, D. (2006). The oligopeptide transporter hPepT1: gateway to the innate immune response. Lab. Invest. 86, 538-546. doi: 10.1038/labinvest.3700423.
    • (2006) Lab. Invest. , vol.86 , pp. 538-546
    • Charrier, L.1    Merlin, D.2
  • 34
    • 79952721660 scopus 로고    scopus 로고
    • Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members
    • doi: 10.1007/s13300-010-0006-4
    • Chen, J., Williams, S., Ho, S., Loraine, H., Hagan, D., Whaley, J. M., et al. (2010). Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members. Diabetes Ther. 1, 57-92. doi: 10.1007/s13300-010-0006-4.
    • (2010) Diabetes Ther. , vol.1 , pp. 57-92
    • Chen, J.1    Williams, S.2    Ho, S.3    Loraine, H.4    Hagan, D.5    Whaley, J.M.6
  • 35
    • 34247245816 scopus 로고    scopus 로고
    • Structure and function of cationic amino acid transporters (CATs)
    • doi: 10.1007/s00232-006-0875-7
    • Closs, E. I., Boissel, J. P., Habermeier, A., and Rotmann, A. (2006). Structure and function of cationic amino acid transporters (CATs). J. Membr. Biol. 213, 67-77. doi: 10.1007/s00232-006-0875-7.
    • (2006) J. Membr. Biol. , vol.213 , pp. 67-77
    • Closs, E.I.1    Boissel, J.P.2    Habermeier, A.3    Rotmann, A.4
  • 36
    • 0141618460 scopus 로고    scopus 로고
    • Glucose transporter-1 (GLUT-1): a potential marker of prognosis in rectal carcinoma?
    • doi: 10.1038/sj.bjc.6601202
    • Cooper, R., Sarioglu, S., Sokmen, S., Fuzun, M., Kupelioglu, A., Valentine, H., et al. (2003). Glucose transporter-1 (GLUT-1): a potential marker of prognosis in rectal carcinoma? Br. J. Cancer 89, 870-876. doi: 10.1038/sj.bjc.6601202.
    • (2003) Br. J. Cancer , vol.89 , pp. 870-876
    • Cooper, R.1    Sarioglu, S.2    Sokmen, S.3    Fuzun, M.4    Kupelioglu, A.5    Valentine, H.6
  • 37
    • 84873048782 scopus 로고    scopus 로고
    • The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function
    • doi: 10.1042/BJ20121248
    • Coothankandaswamy, V., Elangovan, S., Singh, N., Prasad, P. D., Thangaraju, M., and Ganapathy, V. (2013). The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function. Biochem. J. 450, 169-178. doi: 10.1042/BJ20121248.
    • (2013) Biochem. J. , vol.450 , pp. 169-178
    • Coothankandaswamy, V.1    Elangovan, S.2    Singh, N.3    Prasad, P.D.4    Thangaraju, M.5    Ganapathy, V.6
  • 38
    • 84876010793 scopus 로고    scopus 로고
    • Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8
    • doi: 10.1074/jbc.M112.436790
    • Corpe, C. P., Eck, P., Wang, J., Al-Hasani, H., and Levine, M. (2013). Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8. J. Biol. Chem. 288, 9092-9101. doi: 10.1074/jbc.M112.436790.
    • (2013) J. Biol. Chem. , vol.288 , pp. 9092-9101
    • Corpe, C.P.1    Eck, P.2    Wang, J.3    Al-Hasani, H.4    Levine, M.5
  • 39
    • 4544358286 scopus 로고    scopus 로고
    • Betaine in human nutrition
    • Craig, S. A. (2004). Betaine in human nutrition. Am. J. Clin. Nutr. 80, 539-549.
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 539-549
    • Craig, S.A.1
  • 40
    • 84862163151 scopus 로고    scopus 로고
    • The role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism and homeostasis
    • doi: 10.1002/cphy.c110024
    • Cura, A. J., and Carruthers, A. (2012). The role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism and homeostasis. Compr. Physiol. 2, 863-914. doi: 10.1002/cphy.c110024.
    • (2012) Compr. Physiol. , vol.2 , pp. 863-914
    • Cura, A.J.1    Carruthers, A.2
  • 41
    • 0029965863 scopus 로고    scopus 로고
    • Reduction of urinary tract and cardiovascular defects by periconceptional multivitamin supplementation
    • doi: 10.1002/(SICI)1096-8628(19960315)62:2<179::AID-AJMG12>3.0.CO;2-L
    • Czeizel, A. E. (1996). Reduction of urinary tract and cardiovascular defects by periconceptional multivitamin supplementation. Am. J. Med. Genet. 62, 179-183. doi: 10.1002/(SICI)1096-8628(19960315)62:2<179::AID-AJMG12>3.0.CO;2-L.
    • (1996) Am. J. Med. Genet. , vol.62 , pp. 179-183
    • Czeizel, A.E.1
  • 42
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
    • doi: 10.1056/NEJM199212243272602
    • Czeizel, A. E., and Dudas, I. (1992). Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N. Engl. J. Med. 327, 1832-1835. doi: 10.1056/NEJM199212243272602.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudas, I.2
  • 43
    • 45449105159 scopus 로고    scopus 로고
    • How lipid flippases can modulate membrane structure
    • doi: 10.1016/j.bbamem.2008.03.007
    • Devaux, P. F., Herrmann, A., Ohlwein, N., and Kozlov, M. M. (2008). How lipid flippases can modulate membrane structure. Biochim. Biophys. Acta 1778, 1591-1600. doi: 10.1016/j.bbamem.2008.03.007.
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 1591-1600
    • Devaux, P.F.1    Herrmann, A.2    Ohlwein, N.3    Kozlov, M.M.4
  • 46
    • 70349622183 scopus 로고    scopus 로고
    • Facilitative glucose transporter 9, a unique hexose and urate transporter
    • doi: 10.1152/ajpendo.00296.2009
    • Doblado, M., and Moley, K. H. (2009). Facilitative glucose transporter 9, a unique hexose and urate transporter. Am. J. Physiol. Endocrinol. Metab. 297, E831-E835. doi: 10.1152/ajpendo.00296.2009.
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Doblado, M.1    Moley, K.H.2
  • 47
    • 33846910173 scopus 로고    scopus 로고
    • Global reconstruction of the human metabolic network based on genomic and bibliomic data
    • doi: 10.1073/pnas.0610772104
    • Duarte, N. C., Becker, S. A., Jamshidi, N., Thiele, I., Mo, M. L., Vo, T. D., et al. (2007). Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc. Natl. Acad. Sci. U.S.A. 104, 1777-1782. doi: 10.1073/pnas.0610772104.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 1777-1782
    • Duarte, N.C.1    Becker, S.A.2    Jamshidi, N.3    Thiele, I.4    Mo, M.L.5    Vo, T.D.6
  • 50
    • 0033769759 scopus 로고    scopus 로고
    • Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins
    • doi: 10.1007/PL00000621
    • Dutta-Roy, A. K. (2000). Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins. Cell. Mol. Life Sci. 57, 1360-1372. doi: 10.1007/PL00000621.
    • (2000) Cell. Mol. Life Sci. , vol.57 , pp. 1360-1372
    • Dutta-Roy, A.K.1
  • 51
    • 0037184037 scopus 로고    scopus 로고
    • Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition
    • doi: 10.1074/jbc.M203883200
    • Enomoto, A., Wempe, M. F., Tsuchida, H., Shin, H. J., Cha, S. H., Anzai, N., et al. (2002). Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. J. Biol. Chem. 277, 36262-36271. doi: 10.1074/jbc.M203883200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36262-36271
    • Enomoto, A.1    Wempe, M.F.2    Tsuchida, H.3    Shin, H.J.4    Cha, S.H.5    Anzai, N.6
  • 52
    • 84859708410 scopus 로고    scopus 로고
    • Investigational ABC transporter inhibitors
    • doi: 10.1517/13543784.2012.679339
    • Falasca, M., and Linton, K. J. (2012). Investigational ABC transporter inhibitors. Expert Opin. Investig. Drugs 21, 657-666. doi: 10.1517/13543784.2012.679339.
    • (2012) Expert Opin. Investig. Drugs , vol.21 , pp. 657-666
    • Falasca, M.1    Linton, K.J.2
  • 53
    • 34548482011 scopus 로고    scopus 로고
    • CD36: implications in cardiovascular disease
    • doi: 10.1016/j.biocel.2007.03.012
    • Febbraio, M., and Silverstein, R. L. (2007). CD36: implications in cardiovascular disease. Int. J. Biochem. Cell Biol. 39, 2012-2030. doi: 10.1016/j.biocel.2007.03.012.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 2012-2030
    • Febbraio, M.1    Silverstein, R.L.2
  • 54
    • 69949124867 scopus 로고    scopus 로고
    • Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells
    • doi: 10.1016/j.radonc.2009.06.025
    • Feron, O. (2009). Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiother. Oncol. 92, 329-333. doi: 10.1016/j.radonc.2009.06.025.
    • (2009) Radiother. Oncol. , vol.92 , pp. 329-333
    • Feron, O.1
  • 56
    • 75149143363 scopus 로고    scopus 로고
    • ABC transporters in cancer: more than just drug efflux pumps
    • doi: 10.1038/nrc2789
    • Fletcher, J. I., Haber, M., Henderson, M. J., and Norris, M. D. (2010). ABC transporters in cancer: more than just drug efflux pumps. Nat. Rev. Cancer 10, 147-156. doi: 10.1038/nrc2789.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 147-156
    • Fletcher, J.I.1    Haber, M.2    Henderson, M.J.3    Norris, M.D.4
  • 57
    • 79959621970 scopus 로고    scopus 로고
    • Predicting selective drug targets in cancer through metabolic networks
    • doi: 10.1038/msb.2011.35
    • Folger, O., Jerby, L., Frezza, C., Gottlieb, E., Ruppin, E., and Shlomi, T. (2011). Predicting selective drug targets in cancer through metabolic networks. Mol. Syst. Biol. 7, 501. doi: 10.1038/msb.2011.35.
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 501
    • Folger, O.1    Jerby, L.2    Frezza, C.3    Gottlieb, E.4    Ruppin, E.5    Shlomi, T.6
  • 58
    • 78650297251 scopus 로고    scopus 로고
    • The structural basis of secondary active transport mechanisms
    • doi: 10.1016/j.bbabio.2010.10.014
    • Forrest, L. R., Krämer, R., and Ziegler, C. (2011). The structural basis of secondary active transport mechanisms. Biochim. Biophys. Acta 1807, 167-188. doi: 10.1016/j.bbabio.2010.10.014.
    • (2011) Biochim. Biophys. Acta , vol.1807 , pp. 167-188
    • Forrest, L.R.1    Krämer, R.2    Ziegler, C.3
  • 59
    • 80052580351 scopus 로고    scopus 로고
    • Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
    • doi: 10.1038/nature10363
    • Frezza, C., Zheng, L., Folger, O., Rajagopalan, K. N., Mackenzie, E. D., Jerby, L., et al. (2011). Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. Nature 477, 225-228. doi: 10.1038/nature10363.
    • (2011) Nature , vol.477 , pp. 225-228
    • Frezza, C.1    Zheng, L.2    Folger, O.3    Rajagopalan, K.N.4    Mackenzie, E.D.5    Jerby, L.6
  • 60
    • 23044474905 scopus 로고    scopus 로고
    • Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?
    • doi: 10.1016/j.semcancer.2005.04.005
    • Fuchs, B. C., and Bode, B. P. (2005). Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime? Semin. Cancer Biol. 15, 254-266. doi: 10.1016/j.semcancer.2005.04.005.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 254-266
    • Fuchs, B.C.1    Bode, B.P.2
  • 61
    • 0034737775 scopus 로고    scopus 로고
    • Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D-and L-amino acids
    • doi: 10.1074/jbc.275.13.9690
    • Fukasawa, Y., Segawa, H., Kim, J. Y., Chairoungdua, A., Kim, D. K., Matsuo, H., et al. (2000). Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D-and L-amino acids. J. Biol. Chem. 275, 9690-9698. doi: 10.1074/jbc.275.13.9690.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9690-9698
    • Fukasawa, Y.1    Segawa, H.2    Kim, J.Y.3    Chairoungdua, A.4    Kim, D.K.5    Matsuo, H.6
  • 62
    • 84858003666 scopus 로고    scopus 로고
    • ABC transporters and their role in nucleoside and nucleotide drug resistance
    • doi: 10.1016/j.bcp.2011.12.042
    • Fukuda, Y., and Schuetz, J. D. (2012). ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochem. Pharmacol. 83, 1073-1083. doi: 10.1016/j.bcp.2011.12.042.
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 1073-1083
    • Fukuda, Y.1    Schuetz, J.D.2
  • 63
    • 44449118921 scopus 로고    scopus 로고
    • Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
    • doi: 10.1038/nrd2589
    • Furuhashi, M., and Hotamisligil, G. S. (2008). Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat. Rev. Drug Discov. 7, 489-503. doi: 10.1038/nrd2589.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 489-503
    • Furuhashi, M.1    Hotamisligil, G.S.2
  • 64
    • 84861150401 scopus 로고    scopus 로고
    • Rhythmic nucleotide synthesis in the liver: temporal segregation of metabolites
    • doi: 10.1016/j.celrep.2012.03.001
    • Fustin, J. M., Doi, M., Yamada, H., Komatsu, R., Shimba, S., and Okamura, H. (2012). Rhythmic nucleotide synthesis in the liver: temporal segregation of metabolites. Cell Rep. 1, 341-349. doi: 10.1016/j.celrep.2012.03.001.
    • (2012) Cell Rep. , vol.1 , pp. 341-349
    • Fustin, J.M.1    Doi, M.2    Yamada, H.3    Komatsu, R.4    Shimba, S.5    Okamura, H.6
  • 65
    • 57749111596 scopus 로고    scopus 로고
    • Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond
    • doi: 10.1016/j.pharmthera.2008.09.005
    • Ganapathy, V., Thangaraju, M., and Prasad, P. D. (2009). Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol. Ther. 121, 29-40. doi: 10.1016/j.pharmthera.2008.09.005.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 29-40
    • Ganapathy, V.1    Thangaraju, M.2    Prasad, P.D.3
  • 66
    • 77956407882 scopus 로고    scopus 로고
    • HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
    • doi: 10.1038/msb.2010.62
    • Gille, C., Bolling, C., Hoppe, A., Bulik, S., Hoffmann, S., Hubner, K., et al. (2010). HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol. Syst. Biol. 6, 411. doi: 10.1038/msb.2010.62.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 411
    • Gille, C.1    Bolling, C.2    Hoppe, A.3    Bulik, S.4    Hoffmann, S.5    Hubner, K.6
  • 67
  • 68
    • 74949084316 scopus 로고    scopus 로고
    • Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
    • doi: 10.1152/physrev.00003.2009
    • Glatz, J. F., Luiken, J. J., and Bonen, A. (2010). Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol. Rev. 90, 367-417. doi: 10.1152/physrev.00003.2009.
    • (2010) Physiol. Rev. , vol.90 , pp. 367-417
    • Glatz, J.F.1    Luiken, J.J.2    Bonen, A.3
  • 69
    • 2542491777 scopus 로고    scopus 로고
    • The role of ABC transporters in drug resistance, metabolism and toxicity
    • doi: 10.2174/1567201043480036
    • Glavinas, H., Krajcsi, P., Cserepes, J., and Sarkadi, B. (2004). The role of ABC transporters in drug resistance, metabolism and toxicity. Curr. Drug Deliv. 1, 27-42. doi: 10.2174/1567201043480036.
    • (2004) Curr. Drug Deliv. , vol.1 , pp. 27-42
    • Glavinas, H.1    Krajcsi, P.2    Cserepes, J.3    Sarkadi, B.4
  • 70
    • 7244236578 scopus 로고    scopus 로고
    • Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate
    • doi: 10.1074/jbc.M405365200
    • Gopal, E., Fei, Y. J., Sugawara, M., Miyauchi, S., Zhuang, L., Martin, P., et al. (2004). Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. J. Biol. Chem. 279, 44522-44532. doi: 10.1074/jbc.M405365200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44522-44532
    • Gopal, E.1    Fei, Y.J.2    Sugawara, M.3    Miyauchi, S.4    Zhuang, L.5    Martin, P.6
  • 71
    • 33847164080 scopus 로고    scopus 로고
    • Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract
    • doi: 10.1007/s11095-006-9176-1
    • Gopal, E., Miyauchi, S., Martin, P. M., Ananth, S., Roon, P., Smith, S. B., et al. (2007). Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract. Pharm. Res. 24, 575-584. doi: 10.1007/s11095-006-9176-1.
    • (2007) Pharm. Res. , vol.24 , pp. 575-584
    • Gopal, E.1    Miyauchi, S.2    Martin, P.M.3    Ananth, S.4    Roon, P.5    Smith, S.B.6
  • 72
    • 0029789444 scopus 로고    scopus 로고
    • Acyl-CoA binding proteins: multiplicity and function
    • doi: 10.1007/BF02522684
    • Gossett, R. E., Frolov, A. A., Roths, J. B., Behnke, W. D., Kier, A. B., and Schroeder, F. (1996). Acyl-CoA binding proteins: multiplicity and function. Lipids 31, 895-918. doi: 10.1007/BF02522684.
    • (1996) Lipids , vol.31 , pp. 895-918
    • Gossett, R.E.1    Frolov, A.A.2    Roths, J.B.3    Behnke, W.D.4    Kier, A.B.5    Schroeder, F.6
  • 73
    • 77950398194 scopus 로고    scopus 로고
    • Ins and outs of cellular cobalamin transport
    • doi: 10.1182/blood-2009-12-254037
    • Green, R. (2010). Ins and outs of cellular cobalamin transport. Blood 115, 1476-1477. doi: 10.1182/blood-2009-12-254037.
    • (2010) Blood , vol.115 , pp. 1476-1477
    • Green, R.1
  • 74
    • 84856212857 scopus 로고    scopus 로고
    • Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter
    • doi: 10.1016/j.febslet.2011.12.027
    • Grempler, R., Augustin, R., Froehner, S., Hildebrandt, T., Simon, E., Mark, M., et al. (2012). Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter. FEBS Lett. 586, 248-253. doi: 10.1016/j.febslet.2011.12.027.
    • (2012) FEBS Lett. , vol.586 , pp. 248-253
    • Grempler, R.1    Augustin, R.2    Froehner, S.3    Hildebrandt, T.4    Simon, E.5    Mark, M.6
  • 76
    • 0025990550 scopus 로고
    • Effect of taurine on total parenteral nutrition-associated cholestasis
    • doi: 10.1177/0148607191015003247
    • Guertin, F., Roy, C. C., Lepage, G., Perea, A., Giguere, R., Yousef, I., et al. (1991). Effect of taurine on total parenteral nutrition-associated cholestasis. JPEN J. Parenter. Enteral Nutr. 15, 247-251. doi: 10.1177/0148607191015003247.
    • (1991) JPEN J. Parenter. Enteral Nutr. , vol.15 , pp. 247-251
    • Guertin, F.1    Roy, C.C.2    Lepage, G.3    Perea, A.4    Giguere, R.5    Yousef, I.6
  • 78
    • 74749087005 scopus 로고    scopus 로고
    • Low folate transport across intestinal basolateral surface is associated with down-regulation of reduced folate carrier in in vivo model of folate malabsorption
    • doi: 10.1002/iub.153
    • Hamid, A., Kiran, M., Rana, S., and Kaur, J. (2009). Low folate transport across intestinal basolateral surface is associated with down-regulation of reduced folate carrier in in vivo model of folate malabsorption. IUBMB Life 61, 236-243. doi: 10.1002/iub.153.
    • (2009) IUBMB Life , vol.61 , pp. 236-243
    • Hamid, A.1    Kiran, M.2    Rana, S.3    Kaur, J.4
  • 79
    • 33847157867 scopus 로고    scopus 로고
    • Aquaporin expression and cell volume regulation in the SV40 immortalized rat submandibular acinar cell line
    • doi: 10.1007/s00424-006-0158-2
    • Hansen, A. K., and Galtung, H. K. (2007). Aquaporin expression and cell volume regulation in the SV40 immortalized rat submandibular acinar cell line. Pflugers Arch. 453, 787-796. doi: 10.1007/s00424-006-0158-2.
    • (2007) Pflugers Arch. , vol.453 , pp. 787-796
    • Hansen, A.K.1    Galtung, H.K.2
  • 80
    • 37549040241 scopus 로고    scopus 로고
    • Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption
    • doi: 10.1128/MCB.01482-07
    • Hara-Chikuma, M., and Verkman, A. S. (2008). Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption. Mol. Cell. Biol. 28, 326-332. doi: 10.1128/MCB.01482-07.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 326-332
    • Hara-Chikuma, M.1    Verkman, A.S.2
  • 81
    • 23944481843 scopus 로고    scopus 로고
    • Mechanisms of digestion and absorption of dietary vitamin A
    • doi: 10.1146/annurev.nutr.25.050304.092614
    • Harrison, E. H. (2005). Mechanisms of digestion and absorption of dietary vitamin A. Annu. Rev. Nutr. 25, 87-103. doi: 10.1146/annurev.nutr.25.050304.092614.
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 87-103
    • Harrison, E.H.1
  • 82
    • 1342329731 scopus 로고    scopus 로고
    • +-and Cl(-)-coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery
    • doi: 10.1124/jpet.103.057109
    • +-and Cl(-)-coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. J. Pharmacol. Exp. Ther. 308, 1138-1147. doi: 10.1124/jpet.103.057109.
    • (2004) J. Pharmacol. Exp. Ther. , vol.308 , pp. 1138-1147
    • Hatanaka, T.1    Haramura, M.2    Fei, Y.J.3    Miyauchi, S.4    Bridges, C.C.5    Ganapathy, P.S.6
  • 83
    • 0036105474 scopus 로고    scopus 로고
    • New view at C
    • doi: 10.1038/nm0502-445
    • Hediger, M. A. (2002). New view at C. Nat. Med. 8, 445-446. doi: 10.1038/nm0502-445.
    • (2002) Nat. Med. , vol.8 , pp. 445-446
    • Hediger, M.A.1
  • 85
    • 0036484398 scopus 로고    scopus 로고
    • Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice
    • doi: 10.1096/fj.01-0691fje
    • Heller-Stilb, B., Van Roeyen, C., Rascher, K., Hartwig, H. G., Huth, A., Seeliger, M. W., et al. (2002). Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice. FASEB J. 16, 231-233. doi: 10.1096/fj.01-0691fje.
    • (2002) FASEB J. , vol.16 , pp. 231-233
    • Heller-Stilb, B.1    Van Roeyen, C.2    Rascher, K.3    Hartwig, H.G.4    Huth, A.5    Seeliger, M.W.6
  • 86
    • 84874562089 scopus 로고    scopus 로고
    • Systems Biology of cancer: moving toward the integrative study of the metabolic alterations in cancer cells
    • doi: 10.3389/fphys.2012.00481
    • Hernández Patiño, C. E., Jaime-Muñoz, G., and Resendis-Antonio, O. (2013). Systems Biology of cancer: moving toward the integrative study of the metabolic alterations in cancer cells. Front. Physiol. 3:481. doi: 10.3389/fphys.2012.00481.
    • (2013) Front. Physiol. , vol.3 , pp. 481
    • Hernández Patiño, C.E.1    Jaime-Muñoz, G.2    Resendis-Antonio, O.3
  • 88
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • doi: 10.1158/0008-5472.CAN-06-3557
    • Ho, M. M., Ng, A. V., Lam, S., and Hung, J. Y. (2007). Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 67, 4827-4833. doi: 10.1158/0008-5472.CAN-06-3557.
    • (2007) Cancer Res. , vol.67 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 89
    • 0017369222 scopus 로고
    • Vitamin K1 intestinal absorption in vivo: influence of luminal contents on transport
    • Hollander, D., Rim, E., and Muralidhara, K. S. (1977). Vitamin K1 intestinal absorption in vivo: influence of luminal contents on transport. Am. J. Physiol. 232, E69-E74.
    • (1977) Am. J. Physiol. , vol.232
    • Hollander, D.1    Rim, E.2    Muralidhara, K.S.3
  • 90
    • 18144402837 scopus 로고    scopus 로고
    • Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8
    • doi: 10.1158/0008-5472.CAN-05-0048
    • Hong, C., Maunakea, A., Jun, P., Bollen, A. W., Hodgson, J. G., Goldenberg, D. D., et al. (2005). Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8. Cancer Res. 65, 3617-3623. doi: 10.1158/0008-5472.CAN-05-0048.
    • (2005) Cancer Res. , vol.65 , pp. 3617-3623
    • Hong, C.1    Maunakea, A.2    Jun, P.3    Bollen, A.W.4    Hodgson, J.G.5    Goldenberg, D.D.6
  • 91
    • 0030479435 scopus 로고    scopus 로고
    • Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2)
    • doi: 10.1006/geno.1996.0613
    • Hoshide, R., Ikeda, Y., Karashima, S., Matsuura, T., Komaki, S., Kishino, T., et al. (1996). Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2). Genomics 38, 174-178. doi: 10.1006/geno.1996.0613.
    • (1996) Genomics , vol.38 , pp. 174-178
    • Hoshide, R.1    Ikeda, Y.2    Karashima, S.3    Matsuura, T.4    Komaki, S.5    Kishino, T.6
  • 93
    • 27144551314 scopus 로고    scopus 로고
    • Identification of the receptor scavenging hemopexin-heme complexes
    • doi: 10.1182/blood-2005-03-1185
    • Hvidberg, V., Maniecki, M. B., Jacobsen, C., Hojrup, P., Moller, H. J., and Moestrup, S. K. (2005). Identification of the receptor scavenging hemopexin-heme complexes. Blood 106, 2572-2579. doi: 10.1182/blood-2005-03-1185.
    • (2005) Blood , vol.106 , pp. 2572-2579
    • Hvidberg, V.1    Maniecki, M.B.2    Jacobsen, C.3    Hojrup, P.4    Moller, H.J.5    Moestrup, S.K.6
  • 94
    • 33845488122 scopus 로고    scopus 로고
    • Iron supplementation in early childhood: health benefits and risks
    • Iannotti, L. L., Tielsch, J. M., Black, M. M., and Black, R. E. (2006). Iron supplementation in early childhood: health benefits and risks. Am. J. Clin. Nutr. 84, 1261-1276.
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 1261-1276
    • Iannotti, L.L.1    Tielsch, J.M.2    Black, M.M.3    Black, R.E.4
  • 95
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • doi: 10.1038/nrm2336
    • Ikonen, E. (2008). Cellular cholesterol trafficking and compartmentalization. Nat. Rev. Mol. Cell Biol. 9, 125-138. doi: 10.1038/nrm2336.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 125-138
    • Ikonen, E.1
  • 96
    • 84867554554 scopus 로고    scopus 로고
    • Predicting drug targets and biomarkers of cancer via genome-scale metabolic modeling
    • doi: 10.1158/1078-0432.CCR-12-1856
    • Jerby, L., and Ruppin, E. (2012). Predicting drug targets and biomarkers of cancer via genome-scale metabolic modeling. Clin. Cancer Res. 18, 5572-5584. doi: 10.1158/1078-0432.CCR-12-1856.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 5572-5584
    • Jerby, L.1    Ruppin, E.2
  • 97
    • 77956417789 scopus 로고    scopus 로고
    • Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
    • doi: 10.1038/msb.2010.56
    • Jerby, L., Shlomi, T., and Ruppin, E. (2010). Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. Mol. Syst. Biol. 6, 401. doi: 10.1038/msb.2010.56.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 401
    • Jerby, L.1    Shlomi, T.2    Ruppin, E.3
  • 98
    • 84867527044 scopus 로고    scopus 로고
    • Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
    • doi: 10.1158/0008-5472.CAN-12-2215
    • Jerby, L., Wolf, L., Denkert, C., Stein, G. Y., Hilvo, M., Oresic, M., et al. (2012). Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer. Cancer Res. 72, 5712-5720. doi: 10.1158/0008-5472.CAN-12-2215.
    • (2012) Cancer Res. , vol.72 , pp. 5712-5720
    • Jerby, L.1    Wolf, L.2    Denkert, C.3    Stein, G.Y.4    Hilvo, M.5    Oresic, M.6
  • 99
    • 35348860747 scopus 로고    scopus 로고
    • The fatty acid transport protein (FATP) family: very long chain acyl-CoA synthetases or solute carriers?
    • doi: 10.1007/s12031-007-0038-z
    • Jia, Z., Pei, Z., Maiguel, D., Toomer, C. J., and Watkins, P. A. (2007). The fatty acid transport protein (FATP) family: very long chain acyl-CoA synthetases or solute carriers? J. Mol. Neurosci. 33, 25-31. doi: 10.1007/s12031-007-0038-z.
    • (2007) J. Mol. Neurosci. , vol.33 , pp. 25-31
    • Jia, Z.1    Pei, Z.2    Maiguel, D.3    Toomer, C.J.4    Watkins, P.A.5
  • 100
    • 0035685698 scopus 로고    scopus 로고
    • The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)
    • doi: 10.1080/09687680110090456
    • Joost, H. G., and Thorens, B. (2001). The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). Mol. Membr. Biol. 18, 247-256. doi: 10.1080/09687680110090456.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 247-256
    • Joost, H.G.1    Thorens, B.2
  • 101
    • 71449126495 scopus 로고    scopus 로고
    • Novel large-scale deletion (whole exon 7) in the ABCC2 gene in a patient with the Dubin-Johnson syndrome
    • doi: 10.2133/dmpk.24.464
    • Kanda, D., Takagi, H., Kawahara, Y., Yata, Y., Takakusagi, T., Hatanaka, T., et al. (2009). Novel large-scale deletion (whole exon 7) in the ABCC2 gene in a patient with the Dubin-Johnson syndrome. Drug Metab. Pharmacokinet. 24, 464-468. doi: 10.2133/dmpk.24.464.
    • (2009) Drug Metab. Pharmacokinet. , vol.24 , pp. 464-468
    • Kanda, D.1    Takagi, H.2    Kawahara, Y.3    Yata, Y.4    Takakusagi, T.5    Hatanaka, T.6
  • 104
    • 33645280937 scopus 로고    scopus 로고
    • Supplemental conditionally essential nutrients in cardiovascular disease therapy
    • doi: 10.1097/00005082-200601000-00004
    • Kendler, B. S. (2006). Supplemental conditionally essential nutrients in cardiovascular disease therapy. J. Cardiovasc. Nurs. 21, 9-16. doi: 10.1097/00005082-200601000-00004.
    • (2006) J. Cardiovasc. Nurs. , vol.21 , pp. 9-16
    • Kendler, B.S.1
  • 105
    • 20344374445 scopus 로고    scopus 로고
    • Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy
    • doi: 10.1002/glia.20174
    • Kimelberg, H. K. (2005). Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia 50, 389-397. doi: 10.1002/glia.20174.
    • (2005) Glia , vol.50 , pp. 389-397
    • Kimelberg, H.K.1
  • 106
    • 84861372888 scopus 로고    scopus 로고
    • Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes
    • doi: 10.1371/journal.pone.0037378
    • Kiss, K., Brozik, A., Kucsma, N., Toth, A., Gera, M., Berry, L., et al. (2012). Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. PLoS ONE 7:e37378. doi: 10.1371/journal.pone.0037378.
    • (2012) PLoS ONE , vol.7
    • Kiss, K.1    Brozik, A.2    Kucsma, N.3    Toth, A.4    Gera, M.5    Berry, L.6
  • 107
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile acid, and cholesterol transporters: function and regulation
    • doi: 10.1124/pr.109.002014
    • Klaassen, C. D., and Aleksunes, L. M. (2010). Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacol. Rev. 62, 1-96. doi: 10.1124/pr.109.002014.
    • (2010) Pharmacol. Rev. , vol.62 , pp. 1-96
    • Klaassen, C.D.1    Aleksunes, L.M.2
  • 109
    • 0026597481 scopus 로고
    • L-carnitine treatment for congestive heart failure-experimental and clinical study
    • doi: 10.1253/jcj.56.86
    • Kobayashi, A., Masumura, Y., and Yamazaki, N. (1992). L-carnitine treatment for congestive heart failure-experimental and clinical study. Jpn. Circ. J. 56, 86-94. doi: 10.1253/jcj.56.86.
    • (1992) Jpn. Circ. J. , vol.56 , pp. 86-94
    • Kobayashi, A.1    Masumura, Y.2    Yamazaki, N.3
  • 111
  • 112
    • 2642526992 scopus 로고    scopus 로고
    • The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
    • doi: 10.1074/jbc.M313599200
    • Krishnamurthy, P., Ross, D. D., Nakanishi, T., Bailey-Dell, K., Zhou, S., Mercer, K. E., et al. (2004). The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J. Biol. Chem. 279, 24218-24225. doi: 10.1074/jbc.M313599200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24218-24225
    • Krishnamurthy, P.1    Ross, D.D.2    Nakanishi, T.3    Bailey-Dell, K.4    Zhou, S.5    Mercer, K.E.6
  • 113
    • 0034661941 scopus 로고    scopus 로고
    • Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin
    • Kristiansen, M., Aminoff, M., Jacobsen, C., De La Chapelle, A., Krahe, R., Verroust, P. J., et al. (2000). Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin. Blood 96, 405-409.
    • (2000) Blood , vol.96 , pp. 405-409
    • Kristiansen, M.1    Aminoff, M.2    Jacobsen, C.3    De La Chapelle, A.4    Krahe, R.5    Verroust, P.J.6
  • 114
    • 0029820968 scopus 로고    scopus 로고
    • Peptide transporters in the intestine and the kidney
    • doi: 10.1146/annurev.nu.16.070196.000531
    • Leibach, F. H., and Ganapathy, V. (1996). Peptide transporters in the intestine and the kidney. Annu. Rev. Nutr. 16, 99-119. doi: 10.1146/annurev.nu.16.070196.000531.
    • (1996) Annu. Rev. Nutr. , vol.16 , pp. 99-119
    • Leibach, F.H.1    Ganapathy, V.2
  • 115
    • 78650002545 scopus 로고    scopus 로고
    • Large-scale in silico modeling of metabolic interactions between cell types in the human brain
    • doi: 10.1038/nbt.1711
    • Lewis, N. E., Schramm, G., Bordbar, A., Schellenberger, J., Andersen, M. P., Cheng, J. K., et al. (2010). Large-scale in silico modeling of metabolic interactions between cell types in the human brain. Nat. Biotechnol. 28, 1279-1285. doi: 10.1038/nbt.1711.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 1279-1285
    • Lewis, N.E.1    Schramm, G.2    Bordbar, A.3    Schellenberger, J.4    Andersen, M.P.5    Cheng, J.K.6
  • 116
    • 0038153876 scopus 로고    scopus 로고
    • SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers
    • doi: 10.1073/pnas.1430846100
    • Li, H., Myeroff, L., Smiraglia, D., Romero, M. F., Pretlow, T. P., Kasturi, L., et al. (2003). SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proc. Natl. Acad. Sci. U.S.A. 100, 8412-8417. doi: 10.1073/pnas.1430846100.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 8412-8417
    • Li, H.1    Myeroff, L.2    Smiraglia, D.3    Romero, M.F.4    Pretlow, T.P.5    Kasturi, L.6
  • 117
    • 0035010528 scopus 로고    scopus 로고
    • Vitamin C transport systems of mammalian cells
    • doi: 10.1080/09687680110033774
    • Liang, W. J., Johnson, D., and Jarvis, S. M. (2001). Vitamin C transport systems of mammalian cells. Mol. Membr. Biol. 18, 87-95. doi: 10.1080/09687680110033774.
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 87-95
    • Liang, W.J.1    Johnson, D.2    Jarvis, S.M.3
  • 118
    • 42949126711 scopus 로고    scopus 로고
    • The x(c)-cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases
    • doi: 10.1002/jcp.21366
    • Lo, M., Wang, Y. Z., and Gout, P. W. (2008). The x(c)-cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases. J. Cell. Physiol. 215, 593-602. doi: 10.1002/jcp.21366.
    • (2008) J. Cell. Physiol. , vol.215 , pp. 593-602
    • Lo, M.1    Wang, Y.Z.2    Gout, P.W.3
  • 120
    • 9344224557 scopus 로고    scopus 로고
    • Water transport in the brain: role of cotransporters
    • doi: 10.1016/j.neuroscience.2004.06.045
    • Macaulay, N., Hamann, S., and Zeuthen, T. (2004). Water transport in the brain: role of cotransporters. Neuroscience 129, 1031-1044. doi: 10.1016/j.neuroscience.2004.06.045.
    • (2004) Neuroscience , vol.129 , pp. 1031-1044
    • Macaulay, N.1    Hamann, S.2    Zeuthen, T.3
  • 121
    • 12944262229 scopus 로고    scopus 로고
    • Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
    • doi: 10.1002/jcp.20166
    • Macheda, M. L., Rogers, S., and Best, J. D. (2005). Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J. Cell. Physiol. 202, 654-662. doi: 10.1002/jcp.20166.
    • (2005) J. Cell. Physiol. , vol.202 , pp. 654-662
    • Macheda, M.L.1    Rogers, S.2    Best, J.D.3
  • 122
    • 33745792969 scopus 로고    scopus 로고
    • Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma
    • Marce, S., Molina-Arcas, M., Villamor, N., Casado, F. J., Campo, E., Pastor-Anglada, M., et al. (2006). Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. Haematologica 91, 895-902.
    • (2006) Haematologica , vol.91 , pp. 895-902
    • Marce, S.1    Molina-Arcas, M.2    Villamor, N.3    Casado, F.J.4    Campo, E.5    Pastor-Anglada, M.6
  • 123
    • 0041305877 scopus 로고    scopus 로고
    • Membrane transport of folates
    • doi: 10.1016/S0083-6729(03)01012-4
    • Matherly, L. H., and Goldman, D. I. (2003). Membrane transport of folates. Vitam. Horm. 66, 403-456. doi: 10.1016/S0083-6729(03)01012-4.
    • (2003) Vitam. Horm. , vol.66 , pp. 403-456
    • Matherly, L.H.1    Goldman, D.I.2
  • 124
    • 0037121596 scopus 로고    scopus 로고
    • Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment
    • doi: 10.1016/S0304-3940(02)00982-5
    • McKay Hart, A., Wiberg, M., and Terenghi, G. (2002). Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment. Neurosci. Lett. 334, 181-185. doi: 10.1016/S0304-3940(02)00982-5.
    • (2002) Neurosci. Lett. , vol.334 , pp. 181-185
    • McKay Hart, A.1    Wiberg, M.2    Terenghi, G.3
  • 125
    • 84865137460 scopus 로고    scopus 로고
    • Nerveless and gutsy: intestinal nutrient sensing from invertebrates to humans
    • doi: 10.1016/j.semcdb.2012.01.002
    • Miguel-Aliaga, I. (2012). Nerveless and gutsy: intestinal nutrient sensing from invertebrates to humans. Semin. Cell Dev. Biol. 23, 614-620. doi: 10.1016/j.semcdb.2012.01.002.
    • (2012) Semin. Cell Dev. Biol. , vol.23 , pp. 614-620
    • Miguel-Aliaga, I.1
  • 126
    • 77958505117 scopus 로고    scopus 로고
    • ABCA12 dysfunction causes a disorder in glucosylceramide accumulation during keratinocyte differentiation
    • doi: 10.1016/j.jdermsci.2010.08.012
    • Mitsutake, S., Suzuki, C., Akiyama, M., Tsuji, K., Yanagi, T., Shimizu, H., et al. (2010). ABCA12 dysfunction causes a disorder in glucosylceramide accumulation during keratinocyte differentiation. J. Dermatol. Sci. 60, 128-129. doi: 10.1016/j.jdermsci.2010.08.012.
    • (2010) J. Dermatol. Sci. , vol.60 , pp. 128-129
    • Mitsutake, S.1    Suzuki, C.2    Akiyama, M.3    Tsuji, K.4    Yanagi, T.5    Shimizu, H.6
  • 127
    • 1842778906 scopus 로고    scopus 로고
    • Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids
    • doi: 10.1074/jbc.C400059200
    • Miyauchi, S., Gopal, E., Fei, Y. J., and Ganapathy, V. (2004). Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids. J. Biol. Chem. 279, 13293-13296. doi: 10.1074/jbc.C400059200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 13293-13296
    • Miyauchi, S.1    Gopal, E.2    Fei, Y.J.3    Ganapathy, V.4
  • 129
    • 77649196563 scopus 로고    scopus 로고
    • Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease
    • doi: 10.1371/journal.pgen.1000833
    • Morgan, N. V., Morris, M. R., Cangul, H., Gleeson, D., Straatman-Iwanowska, A., Davies, N., et al. (2010). Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease. PLoS Genet. 6:e1000833. doi: 10.1371/journal.pgen.1000833.
    • (2010) PLoS Genet. , vol.6
    • Morgan, N.V.1    Morris, M.R.2    Cangul, H.3    Gleeson, D.4    Straatman-Iwanowska, A.5    Davies, N.6
  • 131
    • 21144443296 scopus 로고    scopus 로고
    • Mechanism and regulation of human intestinal niacin uptake
    • doi: 10.1152/ajpcell.00009.2005
    • Nabokina, S. M., Kashyap, M. L., and Said, H. M. (2005). Mechanism and regulation of human intestinal niacin uptake. Am. J. Physiol. Cell Physiol. 289, C97-C103. doi: 10.1152/ajpcell.00009.2005.
    • (2005) Am. J. Physiol. Cell Physiol. , vol.289
    • Nabokina, S.M.1    Kashyap, M.L.2    Said, H.M.3
  • 132
    • 0034733978 scopus 로고    scopus 로고
    • Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity
    • doi: 10.1016/S0304-3940(00)01169-1
    • Nakauchi, J., Matsuo, H., Kim, D. K., Goto, A., Chairoungdua, A., Cha, S. H., et al. (2000). Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity. Neurosci. Lett. 287, 231-235. doi: 10.1016/S0304-3940(00)01169-1.
    • (2000) Neurosci. Lett. , vol.287 , pp. 231-235
    • Nakauchi, J.1    Matsuo, H.2    Kim, D.K.3    Goto, A.4    Chairoungdua, A.5    Cha, S.H.6
  • 133
    • 45749155204 scopus 로고    scopus 로고
    • Niemann-pick C1-like 1 mediates alpha-tocopherol transport
    • doi: 10.1124/mol.107.043034
    • Narushima, K., Takada, T., Yamanashi, Y., and Suzuki, H. (2008). Niemann-pick C1-like 1 mediates alpha-tocopherol transport. Mol. Pharmacol. 74, 42-49. doi: 10.1124/mol.107.043034.
    • (2008) Mol. Pharmacol. , vol.74 , pp. 42-49
    • Narushima, K.1    Takada, T.2    Yamanashi, Y.3    Suzuki, H.4
  • 135
    • 67650239835 scopus 로고    scopus 로고
    • Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle
    • doi: 10.1074/jbc.M109.004788
    • Nickerson, J. G., Alkhateeb, H., Benton, C. R., Lally, J., Nickerson, J., Han, X. X., et al. (2009). Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle. J. Biol. Chem. 284, 16522-16530. doi: 10.1074/jbc.M109.004788.
    • (2009) J. Biol. Chem. , vol.284 , pp. 16522-16530
    • Nickerson, J.G.1    Alkhateeb, H.2    Benton, C.R.3    Lally, J.4    Nickerson, J.5    Han, X.X.6
  • 136
    • 0035132434 scopus 로고    scopus 로고
    • Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2
    • Ohashi, R., Tamai, I., Nezu Ji, J., Nikaido, H., Hashimoto, N., Oku, A., et al. (2001). Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. Mol. Pharmacol. 59, 358-366.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 358-366
    • Ohashi, R.1    Tamai, I.2    Nezu Ji, J.3    Nikaido, H.4    Hashimoto, N.5    Oku, A.6
  • 137
    • 0033962086 scopus 로고    scopus 로고
    • Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice
    • doi: 10.1038/72869
    • Orso, E., Broccardo, C., Kaminski, W. E., Bottcher, A., Liebisch, G., Drobnik, W., et al. (2000). Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice. Nat. Genet. 24, 192-196. doi: 10.1038/72869.
    • (2000) Nat. Genet. , vol.24 , pp. 192-196
    • Orso, E.1    Broccardo, C.2    Kaminski, W.E.3    Bottcher, A.4    Liebisch, G.5    Drobnik, W.6
  • 138
    • 77749320898 scopus 로고    scopus 로고
    • What is flux balance analysis?
    • doi: 10.1038/nbt.1614
    • Orth, J. D., Thiele, I., and Palsson, B. O. (2010). What is flux balance analysis? Nat. Biotechnol. 28, 245-248. doi: 10.1038/nbt.1614.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 245-248
    • Orth, J.D.1    Thiele, I.2    Palsson, B.O.3
  • 141
    • 34547543603 scopus 로고    scopus 로고
    • Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling
    • doi: 10.1007/BF03174089
    • Pastor-Anglada, M., Errasti-Murugarren, E., Aymerich, I., and Casado, F. J. (2007). Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling. J. Physiol. Biochem. 63, 97-110. doi: 10.1007/BF03174089.
    • (2007) J. Physiol. Biochem. , vol.63 , pp. 97-110
    • Pastor-Anglada, M.1    Errasti-Murugarren, E.2    Aymerich, I.3    Casado, F.J.4
  • 142
    • 77954371389 scopus 로고    scopus 로고
    • The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase
    • doi: 10.1152/ajpgi.00014.2010
    • Pieri, M., Christian, H. C., Wilkins, R. J., Boyd, C. A., and Meredith, D. (2010). The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G136-G143. doi: 10.1152/ajpgi.00014.2010.
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.299
    • Pieri, M.1    Christian, H.C.2    Wilkins, R.J.3    Boyd, C.A.4    Meredith, D.5
  • 143
    • 59849127532 scopus 로고    scopus 로고
    • A review of Donnai-Barrow and facio-oculo-acoustico-renal (DB/FOAR) syndrome: clinical features and differential diagnosis
    • doi: 10.1002/bdra.20534
    • Pober, B. R., Longoni, M., and Noonan, K. M. (2009). A review of Donnai-Barrow and facio-oculo-acoustico-renal (DB/FOAR) syndrome: clinical features and differential diagnosis. Birth Defects Res. Part A Clin. Mol. Teratol. 85, 76-81. doi: 10.1002/bdra.20534.
    • (2009) Birth Defects Res. Part A Clin. Mol. Teratol. , vol.85 , pp. 76-81
    • Pober, B.R.1    Longoni, M.2    Noonan, K.M.3
  • 144
    • 77951069483 scopus 로고    scopus 로고
    • Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly
    • doi: 10.1194/jlr.P001172
    • Polisecki, E., Peter, I., Simon, J. S., Hegele, R. A., Robertson, M., Ford, I., et al. (2010). Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. J. Lipid Res. 51, 1201-1207. doi: 10.1194/jlr.P001172.
    • (2010) J. Lipid Res. , vol.51 , pp. 1201-1207
    • Polisecki, E.1    Peter, I.2    Simon, J.S.3    Hegele, R.A.4    Robertson, M.5    Ford, I.6
  • 145
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • doi: 10.1038/nature04871
    • Pouyssegur, J., Dayan, F., and Mazure, N. M. (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441, 437-443. doi: 10.1038/nature04871.
    • (2006) Nature , vol.441 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 146
    • 34248136952 scopus 로고    scopus 로고
    • A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities
    • doi: 10.2337/db06-1389
    • Prudente, S., Flex, E., Morini, E., Turchi, F., Capponi, D., De Cosmo, S., et al. (2007). A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities. Diabetes 56, 1468-1474. doi: 10.2337/db06-1389.
    • (2007) Diabetes , vol.56 , pp. 1468-1474
    • Prudente, S.1    Flex, E.2    Morini, E.3    Turchi, F.4    Capponi, D.5    De Cosmo, S.6
  • 147
    • 72649089540 scopus 로고    scopus 로고
    • Advances in the understanding of cobalamin assimilation and metabolism
    • doi: 10.1111/j.1365-2141.2009.07937.x
    • Quadros, E. V. (2010). Advances in the understanding of cobalamin assimilation and metabolism. Br. J. Haematol. 148, 195-204. doi: 10.1111/j.1365-2141.2009.07937.x.
    • (2010) Br. J. Haematol. , vol.148 , pp. 195-204
    • Quadros, E.V.1
  • 148
    • 79960676392 scopus 로고    scopus 로고
    • Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes
    • doi: 10.1016/j.plipres.2011.07.001
    • Reboul, E., and Borel, P. (2011). Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes. Prog. Lipid Res. 50, 388-402. doi: 10.1016/j.plipres.2011.07.001.
    • (2011) Prog. Lipid Res. , vol.50 , pp. 388-402
    • Reboul, E.1    Borel, P.2
  • 149
    • 79955595071 scopus 로고    scopus 로고
    • Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters
    • doi: 10.1002/mnfr.201000553
    • Reboul, E., Goncalves, A., Comera, C., Bott, R., Nowicki, M., Landrier, J. F., et al. (2011). Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters. Mol. Nutr. Food Res. 55, 691-702. doi: 10.1002/mnfr.201000553.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 691-702
    • Reboul, E.1    Goncalves, A.2    Comera, C.3    Bott, R.4    Nowicki, M.5    Landrier, J.F.6
  • 150
    • 33646198832 scopus 로고    scopus 로고
    • Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte
    • doi: 10.1074/jbc.M509042200
    • Reboul, E., Klein, A., Bietrix, F., Gleize, B., Malezet-Desmoulins, C., Schneider, M., et al. (2006). Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte. J. Biol. Chem. 281, 4739-4745. doi: 10.1074/jbc.M509042200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 4739-4745
    • Reboul, E.1    Klein, A.2    Bietrix, F.3    Gleize, B.4    Malezet-Desmoulins, C.5    Schneider, M.6
  • 151
    • 34548404574 scopus 로고    scopus 로고
    • Absorption, transport, and tissue delivery of vitamin E
    • doi: 10.1016/j.mam.2007.01.002
    • Rigotti, A. (2007). Absorption, transport, and tissue delivery of vitamin E. Mol. Aspects Med. 28, 423-436. doi: 10.1016/j.mam.2007.01.002.
    • (2007) Mol. Aspects Med. , vol.28 , pp. 423-436
    • Rigotti, A.1
  • 152
    • 84865768271 scopus 로고    scopus 로고
    • A compendium of inborn errors of metabolism mapped onto the human metabolic network
    • doi: 10.1039/C2MB25075F
    • Sahoo, S., Franzson, L., Jonsson, J. J., and Thiele, I. (2012). A compendium of inborn errors of metabolism mapped onto the human metabolic network. Mol. Biosyst. 8, 2545-2558. doi: 10.1039/C2MB25075F.
    • (2012) Mol. Biosyst. , vol.8 , pp. 2545-2558
    • Sahoo, S.1    Franzson, L.2    Jonsson, J.J.3    Thiele, I.4
  • 153
    • 84878949529 scopus 로고    scopus 로고
    • Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells
    • doi: 10.1093/hmg/ddt119
    • Sahoo, S., and Thiele, I. (2013). Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells. Hum. Mol. Genet. 22, 2705-2722. doi: 10.1093/hmg/ddt119.
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 2705-2722
    • Sahoo, S.1    Thiele, I.2
  • 154
    • 0032939163 scopus 로고    scopus 로고
    • Cellular uptake of biotin: mechanisms and regulation
    • Said, H. M. (1999). Cellular uptake of biotin: mechanisms and regulation. J. Nutr. 129, 490S-493S.
    • (1999) J. Nutr. , vol.129
    • Said, H.M.1
  • 155
    • 2342505952 scopus 로고    scopus 로고
    • Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins
    • doi: 10.1146/annurev.physiol.66.032102.144611
    • Said, H. M. (2004). Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins. Annu. Rev. Physiol. 66, 419-446. doi: 10.1146/annurev.physiol.66.032102.144611.
    • (2004) Annu. Rev. Physiol. , vol.66 , pp. 419-446
    • Said, H.M.1
  • 156
    • 79960222400 scopus 로고    scopus 로고
    • Intestinal absorption of water-soluble vitamins in health and disease
    • doi: 10.1042/BJ20110326
    • Said, H. M. (2011). Intestinal absorption of water-soluble vitamins in health and disease. Biochem. J. 437, 357-372. doi: 10.1042/BJ20110326.
    • (2011) Biochem. J. , vol.437 , pp. 357-372
    • Said, H.M.1
  • 157
    • 0027189621 scopus 로고
    • Uptake of riboflavin by intestinal basolateral membrane vesicles: a specialized carrier-mediated process
    • doi: 10.1016/0005-2736(93)90138-p
    • Said, H. M., Hollander, D., and Mohammadkhani, R. (1993). Uptake of riboflavin by intestinal basolateral membrane vesicles: a specialized carrier-mediated process. Biochim. Biophys. Acta Biomembr. 1148, 263-268. doi: 10.1016/0005-2736(93)90138-p.
    • (1993) Biochim. Biophys. Acta Biomembr. , vol.1148 , pp. 263-268
    • Said, H.M.1    Hollander, D.2    Mohammadkhani, R.3
  • 158
    • 0142116209 scopus 로고    scopus 로고
    • A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells: regulation by a PKA-mediated pathway
    • doi: 10.1152/ajpcell.00204.2003
    • Said, H. M., Ortiz, A., and Ma, T. Y. (2003). A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells: regulation by a PKA-mediated pathway. Am. J. Physiol. Cell Physiol. 285, C1219-C1225. doi: 10.1152/ajpcell.00204.2003.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Said, H.M.1    Ortiz, A.2    Ma, T.Y.3
  • 159
    • 73449119238 scopus 로고    scopus 로고
    • Flipping lipids: why an' what's the reason for?
    • doi: 10.1021/cb900163d
    • Sanyal, S., and Menon, A. K. (2009). Flipping lipids: why an' what's the reason for? ACS Chem. Biol. 4, 895-909. doi: 10.1021/cb900163d.
    • (2009) ACS Chem. Biol. , vol.4 , pp. 895-909
    • Sanyal, S.1    Menon, A.K.2
  • 160
    • 84863333022 scopus 로고    scopus 로고
    • Human OCTN2 (SLC22A5) is down-regulated in virus-and nonvirus-mediated cancer
    • doi: 10.1002/cbf.2816
    • Scalise, M., Galluccio, M., Accardi, R., Cornet, I., Tommasino, M., and Indiveri, C. (2012). Human OCTN2 (SLC22A5) is down-regulated in virus-and nonvirus-mediated cancer. Cell Biochem. Funct. 30, 419-425. doi: 10.1002/cbf.2816.
    • (2012) Cell Biochem. Funct. , vol.30 , pp. 419-425
    • Scalise, M.1    Galluccio, M.2    Accardi, R.3    Cornet, I.4    Tommasino, M.5    Indiveri, C.6
  • 161
    • 77956022823 scopus 로고    scopus 로고
    • Physiological roles of taurine in heart and muscle
    • doi: 10.1186/1423-0127-17-S1-S2
    • Schaffer, S. W., Jong, C. J., Ramila, K. C., and Azuma, J. (2010). Physiological roles of taurine in heart and muscle. J. Biomed. Sci. 17(Suppl. 1), S2. doi: 10.1186/1423-0127-17-S1-S2.
    • (2010) J. Biomed. Sci. , vol.17 , Issue.SUPPL. 1
    • Schaffer, S.W.1    Jong, C.J.2    Ramila, K.C.3    Azuma, J.4
  • 162
    • 4344559467 scopus 로고    scopus 로고
    • The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function
    • doi: 10.1177/0148607104028005364
    • Scheepers, A., Joost, H. G., and Schurmann, A. (2004). The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. JPEN J. Parenter. Enteral Nutr. 28, 364-371. doi: 10.1177/0148607104028005364.
    • (2004) JPEN J. Parenter. Enteral Nutr. , vol.28 , pp. 364-371
    • Scheepers, A.1    Joost, H.G.2    Schurmann, A.3
  • 163
    • 79551662521 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
    • doi: 10.1038/nprot.2011.308
    • Schellenberger, J., Que, R., Fleming, R. M., Thiele, I., Orth, J. D., Feist, A. M., et al. (2011). Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat. Protoc. 6, 1290-1307. doi: 10.1038/nprot.2011.308.
    • (2011) Nat. Protoc. , vol.6 , pp. 1290-1307
    • Schellenberger, J.1    Que, R.2    Fleming, R.M.3    Thiele, I.4    Orth, J.D.5    Feist, A.M.6
  • 164
    • 0034889089 scopus 로고    scopus 로고
    • Plasma and liver carnitine status of children with chronic liver disease and cirrhosis
    • doi: 10.1046/j.1442-200X.2001.01423.x
    • Selimoglu, M. A., Aydogdu, S., Yagci, R. V., and Huseyinov, A. (2001). Plasma and liver carnitine status of children with chronic liver disease and cirrhosis. Pediatr. Int. 43, 391-395. doi: 10.1046/j.1442-200X.2001.01423.x.
    • (2001) Pediatr. Int. , vol.43 , pp. 391-395
    • Selimoglu, M.A.1    Aydogdu, S.2    Yagci, R.V.3    Huseyinov, A.4
  • 165
    • 4444377675 scopus 로고    scopus 로고
    • Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19
    • doi: 10.1038/ng1406
    • Seow, H. F., Broer, S., Broer, A., Bailey, C. G., Potter, S. J., Cavanaugh, J. A., et al. (2004). Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19. Nat. Genet. 36, 1003-1007. doi: 10.1038/ng1406.
    • (2004) Nat. Genet. , vol.36 , pp. 1003-1007
    • Seow, H.F.1    Broer, S.2    Broer, A.3    Bailey, C.G.4    Potter, S.J.5    Cavanaugh, J.A.6
  • 166
    • 0034825921 scopus 로고    scopus 로고
    • Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures
    • Shu, C., Shen, H., Hopfer, U., and Smith, D. E. (2001). Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures. Drug Metab. Dispos. 29, 1307-1315.
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 1307-1315
    • Shu, C.1    Shen, H.2    Hopfer, U.3    Smith, D.E.4
  • 167
    • 37649030067 scopus 로고    scopus 로고
    • Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates
    • CD004869. doi: 10.1002/14651858.CD004869.pub2.
    • Soghier, L. M., and Brion, L. P. (2006). Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. Cochrane Database Syst. Rev. CD004869. doi: 10.1002/14651858.CD004869.pub2.
    • (2006) Cochrane Database Syst. Rev
    • Soghier, L.M.1    Brion, L.P.2
  • 168
    • 36148956147 scopus 로고    scopus 로고
    • Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+)
    • doi: 10.1152/ajpgi.00233.2007
    • Srinivas, S. R., Prasad, P. D., Umapathy, N. S., Ganapathy, V., and Shekhawat, P. S. (2007). Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). Am. J. Physiol. Gastrointest. Liver Physiol. 293, G1046-G1053. doi: 10.1152/ajpgi.00233.2007.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293
    • Srinivas, S.R.1    Prasad, P.D.2    Umapathy, N.S.3    Ganapathy, V.4    Shekhawat, P.S.5
  • 169
    • 1242317654 scopus 로고    scopus 로고
    • A current review of fatty acid transport proteins (SLC27)
    • doi: 10.1007/s00424-003-1106-z
    • Stahl, A. (2004). A current review of fatty acid transport proteins (SLC27). Pflugers Arch. 447, 722-727. doi: 10.1007/s00424-003-1106-z.
    • (2004) Pflugers Arch. , vol.447 , pp. 722-727
    • Stahl, A.1
  • 170
    • 0035430443 scopus 로고    scopus 로고
    • Fatty acid transport proteins: a current view of a growing family
    • doi: 10.1016/S1043-2760(01)00427-1
    • Stahl, A., Gimeno, R. E., Tartaglia, L. A., and Lodish, H. F. (2001). Fatty acid transport proteins: a current view of a growing family. Trends Endocrinol. Metab. 12, 266-273. doi: 10.1016/S1043-2760(01)00427-1.
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 266-273
    • Stahl, A.1    Gimeno, R.E.2    Tartaglia, L.A.3    Lodish, H.F.4
  • 172
    • 0033778232 scopus 로고    scopus 로고
    • The cytoplasmic fatty-acid-binding proteins: thirty years and counting
    • doi: 10.1007/PL00000620
    • Stewart, J. M. (2000). The cytoplasmic fatty-acid-binding proteins: thirty years and counting. Cell. Mol. Life Sci. 57, 1345-1359. doi: 10.1007/PL00000620.
    • (2000) Cell. Mol. Life Sci. , vol.57 , pp. 1345-1359
    • Stewart, J.M.1
  • 173
    • 80054773593 scopus 로고    scopus 로고
    • Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake
    • doi: 10.1016/j.bbamem.2011.08.004
    • Subramanian, V. S., Subramanya, S. B., Rapp, L., Marchant, J. S., Ma, T. Y., and Said, H. M. (2011). Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. Biochim. Biophys. Acta 1808, 3016-3021. doi: 10.1016/j.bbamem.2011.08.004.
    • (2011) Biochim. Biophys. Acta , vol.1808 , pp. 3016-3021
    • Subramanian, V.S.1    Subramanya, S.B.2    Rapp, L.3    Marchant, J.S.4    Ma, T.Y.5    Said, H.M.6
  • 174
    • 78649859188 scopus 로고    scopus 로고
    • Hypoxia induced upregulation and function of the thiamine transporter, SLC19A3 in a breast cancer cell line
    • doi: 10.4161/cbt.10.11.13444
    • Sweet, R., Paul, A., and Zastre, J. (2010). Hypoxia induced upregulation and function of the thiamine transporter, SLC19A3 in a breast cancer cell line. Cancer Biol. Ther. 10, 1101-1111. doi: 10.4161/cbt.10.11.13444.
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 1101-1111
    • Sweet, R.1    Paul, A.2    Zastre, J.3
  • 175
    • 0036076780 scopus 로고    scopus 로고
    • Characterization of methotrexate transport and its drug interactions with human organic anion transporters
    • doi: 10.1124/jpet.102.034330
    • Takeda, M., Khamdang, S., Narikawa, S., Kimura, H., Hosoyamada, M., Cha, S. H., et al. (2002). Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J. Pharmacol. Exp. Ther. 302, 666-671. doi: 10.1124/jpet.102.034330.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 666-671
    • Takeda, M.1    Khamdang, S.2    Narikawa, S.3    Kimura, H.4    Hosoyamada, M.5    Cha, S.H.6
  • 176
    • 0029416927 scopus 로고
    • Na(+)-and Cl(-)-dependent transport of taurine at the blood-brain barrier
    • doi: 10.1016/0006-2952(95)02046-2
    • Tamai, I., Senmaru, M., Terasaki, T., and Tsuji, A. (1995). Na(+)-and Cl(-)-dependent transport of taurine at the blood-brain barrier. Biochem. Pharmacol. 50, 1783-1793. doi: 10.1016/0006-2952(95)02046-2.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1783-1793
    • Tamai, I.1    Senmaru, M.2    Terasaki, T.3    Tsuji, A.4
  • 177
    • 10444246526 scopus 로고    scopus 로고
    • +-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose
    • doi: 10.1016/j.lfs.2004.10.016
    • +-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose. Life Sci. 76, 1039-1050. doi: 10.1016/j.lfs.2004.10.016.
    • (2005) Life Sci. , vol.76 , pp. 1039-1050
    • Tazawa, S.1    Yamato, T.2    Fujikura, H.3    Hiratochi, M.4    Itoh, F.5    Tomae, M.6
  • 178
    • 0015963101 scopus 로고
    • Dicarboxylic aminoaciduria: an inborn error of glutamate and aspartate transport with metabolic implications, in combination with a hyperprolinemia
    • doi: 10.1016/0026-0495(74)90108-5
    • Teijema, H. L., Van Gelderen, H. H., Giesberts, M. A., and Laurent De Angulo, M. S. (1974). Dicarboxylic aminoaciduria: an inborn error of glutamate and aspartate transport with metabolic implications, in combination with a hyperprolinemia. Metab. Clin. Exp. 23, 115-123. doi: 10.1016/0026-0495(74)90108-5.
    • (1974) Metab. Clin. Exp. , vol.23 , pp. 115-123
    • Teijema, H.L.1    Van Gelderen, H.H.2    Giesberts, M.A.3    Laurent De Angulo, M.S.4
  • 179
    • 0033042420 scopus 로고    scopus 로고
    • Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2
    • Terada, T., Sawada, K., Saito, H., Hashimoto, Y., and Inui, K. (1999). Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2. Am. J. Physiol. 276, G1435-G1441.
    • (1999) Am. J. Physiol. , vol.276
    • Terada, T.1    Sawada, K.2    Saito, H.3    Hashimoto, Y.4    Inui, K.5
  • 180
    • 52549103966 scopus 로고    scopus 로고
    • Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer
    • discussion: 1781-1772. doi: 10.1007/s11605-008-0573-0
    • Thangaraju, M., Cresci, G., Itagaki, S., Mellinger, J., Browning, D. D., Berger, F. G., et al. (2008). Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer. J. Gastrointest. Surg. 12, 1773-1781. discussion: 1781-1772. doi: 10.1007/s11605-008-0573-0.
    • (2008) J. Gastrointest. Surg. , vol.12 , pp. 1773-1781
    • Thangaraju, M.1    Cresci, G.2    Itagaki, S.3    Mellinger, J.4    Browning, D.D.5    Berger, F.G.6
  • 181
    • 33846232686 scopus 로고    scopus 로고
    • SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases
    • doi: 10.1158/0008-5472.CAN-06-1950
    • Thangaraju, M., Gopal, E., Martin, P. M., Ananth, S., Smith, S. B., Prasad, P. D., et al. (2006). SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases. Cancer Res. 66, 11560-11564. doi: 10.1158/0008-5472.CAN-06-1950.
    • (2006) Cancer Res. , vol.66 , pp. 11560-11564
    • Thangaraju, M.1    Gopal, E.2    Martin, P.M.3    Ananth, S.4    Smith, S.B.5    Prasad, P.D.6
  • 182
    • 75149129569 scopus 로고    scopus 로고
    • A protocol for generating a high-quality genome-scale metabolic reconstruction
    • doi: 10.1038/nprot.2009.203
    • Thiele, I., and Palsson, B. O. (2010a). A protocol for generating a high-quality genome-scale metabolic reconstruction. Nat. Protoc. 5, 93-121. doi: 10.1038/nprot.2009.203.
    • (2010) Nat. Protoc. , vol.5 , pp. 93-121
    • Thiele, I.1    Palsson, B.O.2
  • 183
    • 77951122415 scopus 로고    scopus 로고
    • Reconstruction annotation jamborees: a community approach to systems biology
    • doi: 10.1038/msb.2010.15
    • Thiele, I., and Palsson, B. O. (2010b). Reconstruction annotation jamborees: a community approach to systems biology. Mol. Syst. Biol. 6, 361. doi: 10.1038/msb.2010.15.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 361
    • Thiele, I.1    Palsson, B.O.2
  • 184
    • 84877315835 scopus 로고    scopus 로고
    • A community-driven global reconstruction of human metabolism
    • doi: 10.1038/nbt.2488
    • Thiele, I., Swainston, N., and Fleming, R. M. T., Hoppe, A., Sahoo, S., Aurich, M. K., et al. (2013). A community-driven global reconstruction of human metabolism. Nat. Biotechnol. 31, 419-425. doi: 10.1038/nbt.2488.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 419-425
    • Thiele, I.1    Swainston, N.2    Fleming, R.M.T.3    Hoppe, A.4    Sahoo, S.5    Aurich, M.K.6
  • 185
    • 74949118966 scopus 로고    scopus 로고
    • Glucose transporters in the 21st Century
    • doi: 10.1152/ajpendo.00712.2009
    • Thorens, B., and Mueckler, M. (2010). Glucose transporters in the 21st Century. Am. J. Physiol. Endocrinol. Metab. 298, E141-E145. doi: 10.1152/ajpendo.00712.2009.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.298
    • Thorens, B.1    Mueckler, M.2
  • 186
    • 79960126760 scopus 로고    scopus 로고
    • rBioNet: A COBRA toolbox extension for reconstructing high-quality biochemical networks
    • doi: 10.1093/bioinformatics/btr308
    • Thorleifsson, S. G., and Thiele, I. (2011). rBioNet: A COBRA toolbox extension for reconstructing high-quality biochemical networks. Bioinformatics 27, 2009-2010. doi: 10.1093/bioinformatics/btr308.
    • (2011) Bioinformatics , vol.27 , pp. 2009-2010
    • Thorleifsson, S.G.1    Thiele, I.2
  • 187
    • 34347379290 scopus 로고    scopus 로고
    • +-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine
    • doi: 10.1113/expphysiol.2005.029959
    • +-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine. Exp. Physiol. 92, 603-619. doi: 10.1113/expphysiol.2005.029959.
    • (2007) Exp. Physiol. , vol.92 , pp. 603-619
    • Thwaites, D.T.1    Anderson, C.M.2
  • 188
    • 0027529451 scopus 로고
    • Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes
    • Thwaites, D. T., Brown, C. D., Hirst, B. H., and Simmons, N. L. (1993). Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes. J. Biol. Chem. 268, 7640-7642.
    • (1993) J. Biol. Chem. , vol.268 , pp. 7640-7642
    • Thwaites, D.T.1    Brown, C.D.2    Hirst, B.H.3    Simmons, N.L.4
  • 189
    • 41949113418 scopus 로고    scopus 로고
    • How does folic acid cure heart attacks?
    • doi: 10.1161/CIRCULATIONAHA.108.766105
    • Tian, R., and Ingwall, J. S. (2008). How does folic acid cure heart attacks? Circulation 117, 1772-1774. doi: 10.1161/CIRCULATIONAHA.108.766105.
    • (2008) Circulation , vol.117 , pp. 1772-1774
    • Tian, R.1    Ingwall, J.S.2
  • 190
  • 191
    • 0019985118 scopus 로고
    • Periconceptional supplementation with vitamins and folic acid to prevent recurrence of cleft lip
    • doi: 10.1016/S0140-6736(82)91063-7
    • Tolarova, M. (1982). Periconceptional supplementation with vitamins and folic acid to prevent recurrence of cleft lip. Lancet 2, 217. doi: 10.1016/S0140-6736(82)91063-7.
    • (1982) Lancet , vol.2 , pp. 217
    • Tolarova, M.1
  • 192
    • 79551646271 scopus 로고    scopus 로고
    • Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failure
    • doi: 10.2174/187152010794473975
    • Toyoda, Y., and Ishikawa, T. (2010). Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failure. Anticancer Agents Med. Chem. 10, 617-624. doi: 10.2174/187152010794473975.
    • (2010) Anticancer Agents Med. Chem. , vol.10 , pp. 617-624
    • Toyoda, Y.1    Ishikawa, T.2
  • 193
    • 77749262144 scopus 로고    scopus 로고
    • Aquaporin water channels in transepithelial fluid transport
    • doi: 10.2152/jmi.56.179
    • Tradtrantip, L., Tajima, M., Li, L., and Verkman, A. S. (2009). Aquaporin water channels in transepithelial fluid transport. J. Med. Invest. 56(Suppl.), 179-184. doi: 10.2152/jmi.56.179.
    • (2009) J. Med. Invest. , vol.56 , Issue.SUPPL. , pp. 179-184
    • Tradtrantip, L.1    Tajima, M.2    Li, L.3    Verkman, A.S.4
  • 194
    • 9244234407 scopus 로고    scopus 로고
    • Heme transport exhibits polarity in Caco-2 cells: evidence for an active and membrane protein-mediated process
    • doi: 10.1152/ajpgi.00157.2004
    • Uc, A., Stokes, J. B., and Britigan, B. E. (2004). Heme transport exhibits polarity in Caco-2 cells: evidence for an active and membrane protein-mediated process. Am. J. Physiol. Gastrointest. Liver Physiol. 287, G1150-G1157. doi: 10.1152/ajpgi.00157.2004.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.287
    • Uc, A.1    Stokes, J.B.2    Britigan, B.E.3
  • 195
    • 84872763089 scopus 로고    scopus 로고
    • Biotin uptake by T47D breast cancer cells: functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT)
    • doi: 10.1016/j.ijpharm.2012.10.047
    • Vadlapudi, A. D., Vadlapatla, R. K., Pal, D., and Mitra, A. K. (2012). Biotin uptake by T47D breast cancer cells: functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT). Int. J. Pharm. 441, 535-543. doi: 10.1016/j.ijpharm.2012.10.047.
    • (2012) Int. J. Pharm. , vol.441 , pp. 535-543
    • Vadlapudi, A.D.1    Vadlapatla, R.K.2    Pal, D.3    Mitra, A.K.4
  • 196
    • 80053280649 scopus 로고    scopus 로고
    • Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1
    • doi: 10.1042/BJ20110905
    • Vandenberg, R. J., Handford, C. A., Campbell, E. M., Ryan, R. M., and Yool, A. J. (2011). Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1. Biochem. J. 439, 333-340. doi: 10.1042/BJ20110905.
    • (2011) Biochem. J. , vol.439 , pp. 333-340
    • Vandenberg, R.J.1    Handford, C.A.2    Campbell, E.M.3    Ryan, R.M.4    Yool, A.J.5
  • 197
    • 0031731915 scopus 로고    scopus 로고
    • Glucose transporter expression in brain: relationship to cerebral glucose utilization
    • doi: 10.1159/000017333
    • Vannucci, S. J., Clark, R. R., Koehler-Stec, E., Li, K., Smith, C. B., Davies, P., et al. (1998). Glucose transporter expression in brain: relationship to cerebral glucose utilization. Dev. Neurosci. 20, 369-379. doi: 10.1159/000017333.
    • (1998) Dev. Neurosci. , vol.20 , pp. 369-379
    • Vannucci, S.J.1    Clark, R.R.2    Koehler-Stec, E.3    Li, K.4    Smith, C.B.5    Davies, P.6
  • 198
    • 0035899990 scopus 로고    scopus 로고
    • Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues
    • doi: 10.1021/bi011345c
    • Vekony, N., Wolf, S., Boissel, J. P., Gnauert, K., and Closs, E. I. (2001). Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry 40, 12387-12394. doi: 10.1021/bi011345c.
    • (2001) Biochemistry , vol.40 , pp. 12387-12394
    • Vekony, N.1    Wolf, S.2    Boissel, J.P.3    Gnauert, K.4    Closs, E.I.5
  • 199
    • 24344497831 scopus 로고    scopus 로고
    • More than just water channels: unexpected cellular roles of aquaporins
    • doi: 10.1242/jcs.02519
    • Verkman, A. S. (2005). More than just water channels: unexpected cellular roles of aquaporins. J. Cell Sci. 118, 3225-3232. doi: 10.1242/jcs.02519.
    • (2005) J. Cell Sci. , vol.118 , pp. 3225-3232
    • Verkman, A.S.1
  • 200
    • 84855932788 scopus 로고    scopus 로고
    • Aquaporins in clinical medicine
    • doi: 10.1146/annurev-med-043010-193843
    • Verkman, A. S. (2012). Aquaporins in clinical medicine. Annu. Rev. Med. 63, 303-316. doi: 10.1146/annurev-med-043010-193843.
    • (2012) Annu. Rev. Med. , vol.63 , pp. 303-316
    • Verkman, A.S.1
  • 201
    • 43049138319 scopus 로고    scopus 로고
    • Aquaporins-new players in cancer biology
    • doi: 10.1007/s00109-008-0303-9
    • Verkman, A. S., Hara-Chikuma, M., and Papadopoulos, M. C. (2008). Aquaporins-new players in cancer biology. J. Mol. Med. 86, 523-529. doi: 10.1007/s00109-008-0303-9.
    • (2008) J. Mol. Med. , vol.86 , pp. 523-529
    • Verkman, A.S.1    Hara-Chikuma, M.2    Papadopoulos, M.C.3
  • 202
    • 25444530047 scopus 로고    scopus 로고
    • Transcriptional regulation of hepatobiliary transport systems in health and disease: implications for a rationale approach to the treatment of intrahepatic cholestasis
    • Wagner, M., and Trauner, M. (2005). Transcriptional regulation of hepatobiliary transport systems in health and disease: implications for a rationale approach to the treatment of intrahepatic cholestasis. Ann. Hepatol. 4, 77-99.
    • (2005) Ann. Hepatol. , vol.4 , pp. 77-99
    • Wagner, M.1    Trauner, M.2
  • 203
    • 84863984526 scopus 로고    scopus 로고
    • SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE)
    • doi: 10.1007/s10549-011-1925-0
    • Wang, C., Uray, I. P., Mazumdar, A., Mayer, J. A., and Brown, P. H. (2012a). SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE). Breast Cancer Res. Treat. 134, 101-115. doi: 10.1007/s10549-011-1925-0.
    • (2012) Breast Cancer Res. Treat. , vol.134 , pp. 101-115
    • Wang, C.1    Uray, I.P.2    Mazumdar, A.3    Mayer, J.A.4    Brown, P.H.5
  • 204
    • 84870933131 scopus 로고    scopus 로고
    • Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
    • doi: 10.1186/1752-0509-6-153
    • Wang, Y., Eddy, J. A., and Price, N. D. (2012b). Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE. BMC Syst. Biol. 6:153. doi: 10.1186/1752-0509-6-153.
    • (2012) BMC Syst. Biol. , vol.6 , pp. 153
    • Wang, Y.1    Eddy, J.A.2    Price, N.D.3
  • 205
    • 79951711772 scopus 로고    scopus 로고
    • Inborn errors of cobalamin absorption and metabolism
    • doi: 10.1002/ajmg.c.30288
    • Watkins, D., and Rosenblatt, D. S. (2011). Inborn errors of cobalamin absorption and metabolism. Am. J. Med. Genet. C Semin. Med. Genet. 157, 33-44. doi: 10.1002/ajmg.c.30288.
    • (2011) Am. J. Med. Genet. C Semin. Med. Genet. , vol.157 , pp. 33-44
    • Watkins, D.1    Rosenblatt, D.S.2
  • 206
    • 70049104336 scopus 로고    scopus 로고
    • Genetic disorders of surfactant dysfunction
    • doi: 10.2350/09-01-0586.1
    • Wert, S. E., Whitsett, J. A., and Nogee, L. M. (2009). Genetic disorders of surfactant dysfunction. Pediatr. Dev. Pathol. 12, 253-274. doi: 10.2350/09-01-0586.1.
    • (2009) Pediatr. Dev. Pathol. , vol.12 , pp. 253-274
    • Wert, S.E.1    Whitsett, J.A.2    Nogee, L.M.3
  • 207
    • 54049093319 scopus 로고    scopus 로고
    • Mechanisms of heme iron absorption: current questions and controversies
    • doi: 10.3748/wjg.14.4101
    • West, A. R., and Oates, P. S. (2008). Mechanisms of heme iron absorption: current questions and controversies. World J. Gastroenterol. 14, 4101-4110. doi: 10.3748/wjg.14.4101.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 4101-4110
    • West, A.R.1    Oates, P.S.2
  • 208
    • 23944482400 scopus 로고    scopus 로고
    • Regulation of vitamin C transport
    • doi: 10.1146/annurev.nutr.25.050304.092647
    • Wilson, J. X. (2005). Regulation of vitamin C transport. Annu. Rev. Nutr. 25, 105-125. doi: 10.1146/annurev.nutr.25.050304.092647.
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 105-125
    • Wilson, J.X.1
  • 209
    • 77952432489 scopus 로고    scopus 로고
    • Evolutionary ancestry and novel functions of the mammalian glucose transporter (GLUT) family
    • doi: 10.1186/1471-2148-10-152
    • Wilson-O'Brien, A. L., Patron, N., and Rogers, S. (2010). Evolutionary ancestry and novel functions of the mammalian glucose transporter (GLUT) family. BMC Evol. Biol. 10:152. doi: 10.1186/1471-2148-10-152.
    • (2010) BMC Evol. Biol. , vol.10 , pp. 152
    • Wilson-O'Brien, A.L.1    Patron, N.2    Rogers, S.3
  • 210
    • 0037097030 scopus 로고    scopus 로고
    • Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity
    • doi: 10.1042/BJ20020084
    • Wolf, S., Janzen, A., Vekony, N., Martine, U., Strand, D., and Closs, E. I. (2002). Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. Biochem. J. 364, 767-775. doi: 10.1042/BJ20020084.
    • (2002) Biochem. J. , vol.364 , pp. 767-775
    • Wolf, S.1    Janzen, A.2    Vekony, N.3    Martine, U.4    Strand, D.5    Closs, E.I.6
  • 211
    • 0037267005 scopus 로고    scopus 로고
    • Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins
    • doi: 10.1079/BJN2002763
    • Wood, I. S., and Trayhurn, P. (2003). Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Br. J. Nutr. 89, 3-9. doi: 10.1079/BJN2002763.
    • (2003) Br. J. Nutr. , vol.89 , pp. 3-9
    • Wood, I.S.1    Trayhurn, P.2
  • 212
    • 33846023326 scopus 로고    scopus 로고
    • Active sugar transport in health and disease
    • doi: 10.1111/j.1365-2796.2006.01746.x
    • Wright, E. M., Hirayama, B. A., and Loo, D. F. (2007). Active sugar transport in health and disease. J. Intern. Med. 261, 32-43. doi: 10.1111/j.1365-2796.2006.01746.x.
    • (2007) J. Intern. Med. , vol.261 , pp. 32-43
    • Wright, E.M.1    Hirayama, B.A.2    Loo, D.F.3
  • 213
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • doi: 10.1152/physrev.00055.2009
    • Wright, E. M., Loo, D. D., and Hirayama, B. A. (2011). Biology of human sodium glucose transporters. Physiol. Rev. 91, 733-794. doi: 10.1152/physrev.00055.2009.
    • (2011) Physiol. Rev. , vol.91 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.2    Hirayama, B.A.3
  • 214
    • 0036939298 scopus 로고    scopus 로고
    • GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms
    • doi: 10.1006/geno.2002.7010
    • Wu, X., and Freeze, H. H. (2002). GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms. Genomics 80, 553-557. doi: 10.1006/geno.2002.7010.
    • (2002) Genomics , vol.80 , pp. 553-557
    • Wu, X.1    Freeze, H.H.2
  • 215
    • 77956958965 scopus 로고    scopus 로고
    • Transport of L-carnitine in human corneal and conjunctival epithelial cells
    • Xu, S., Flanagan, J. L., Simmons, P. A., Vehige, J., Willcox, M. D., and Garrett, Q. (2010). Transport of L-carnitine in human corneal and conjunctival epithelial cells. Mol. Vis. 16, 1823-1831.
    • (2010) Mol. Vis. , vol.16 , pp. 1823-1831
    • Xu, S.1    Flanagan, J.L.2    Simmons, P.A.3    Vehige, J.4    Willcox, M.D.5    Garrett, Q.6
  • 216
    • 0032935034 scopus 로고    scopus 로고
    • Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations
    • Yabuuchi, H., Tamai, I., Nezu, J., Sakamoto, K., Oku, A., Shimane, M., et al. (1999). Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. J. Pharmacol. Exp. Ther. 289, 768-773.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 768-773
    • Yabuuchi, H.1    Tamai, I.2    Nezu, J.3    Sakamoto, K.4    Oku, A.5    Shimane, M.6
  • 217
    • 0026580107 scopus 로고
    • Cloning of a Na(+)-and Cl(-)-dependent betaine transporter that is regulated by hypertonicity
    • Yamauchi, A., Uchida, S., Kwon, H. M., Preston, A. S., Robey, R. B., Garcia-Perez, A., et al. (1992). Cloning of a Na(+)-and Cl(-)-dependent betaine transporter that is regulated by hypertonicity. J. Biol. Chem. 267, 649-652.
    • (1992) J. Biol. Chem. , vol.267 , pp. 649-652
    • Yamauchi, A.1    Uchida, S.2    Kwon, H.M.3    Preston, A.S.4    Robey, R.B.5    Garcia-Perez, A.6
  • 218
    • 84869400098 scopus 로고    scopus 로고
    • Hyperosmotic induction of aquaporin expression in rat astrocytes through a different MAPK pathway
    • doi: 10.1002/jcb.24308
    • Yang, M., Gao, F., Liu, H., Yu, W. H., Zhuo, F., Qiu, G. P., et al. (2013). Hyperosmotic induction of aquaporin expression in rat astrocytes through a different MAPK pathway. J. Cell. Biochem. 114, 111-119. doi: 10.1002/jcb.24308.
    • (2013) J. Cell. Biochem. , vol.114 , pp. 111-119
    • Yang, M.1    Gao, F.2    Liu, H.3    Yu, W.H.4    Zhuo, F.5    Qiu, G.P.6
  • 219
    • 77956547392 scopus 로고    scopus 로고
    • Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin
    • doi: 10.1074/jbc.M110.119131
    • Yang, Z., Philips, J. D., Doty, R. T., Giraudi, P., Ostrow, J. D., Tiribelli, C., et al. (2010). Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin. J. Biol. Chem. 285, 28874-28882. doi: 10.1074/jbc.M110.119131.
    • (2010) J. Biol. Chem. , vol.285 , pp. 28874-28882
    • Yang, Z.1    Philips, J.D.2    Doty, R.T.3    Giraudi, P.4    Ostrow, J.D.5    Tiribelli, C.6
  • 220
    • 77953790155 scopus 로고    scopus 로고
    • Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain
    • doi: 10.3945/jn.110.122911
    • Yao, Y., Yonezawa, A., Yoshimatsu, H., Masuda, S., Katsura, T., and Inui, K. (2010). Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain. J. Nutr. 140, 1220-1226. doi: 10.3945/jn.110.122911.
    • (2010) J. Nutr. , vol.140 , pp. 1220-1226
    • Yao, Y.1    Yonezawa, A.2    Yoshimatsu, H.3    Masuda, S.4    Katsura, T.5    Inui, K.6
  • 221
    • 0033545980 scopus 로고    scopus 로고
    • Aquaporin-6: an intracellular vesicle water channel protein in renal epithelia
    • doi: 10.1073/pnas.96.10.5808
    • Yasui, M., Kwon, T. H., Knepper, M. A., Nielsen, S., and Agre, P. (1999). Aquaporin-6: an intracellular vesicle water channel protein in renal epithelia. Proc. Natl. Acad. Sci. U.S.A. 96, 5808-5813. doi: 10.1073/pnas.96.10.5808.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 5808-5813
    • Yasui, M.1    Kwon, T.H.2    Knepper, M.A.3    Nielsen, S.4    Agre, P.5
  • 222
    • 0035346485 scopus 로고    scopus 로고
    • A phylogenetic framework for the aquaporin family in eukaryotes
    • doi: 10.1007/s002390010169
    • Zardoya, R., and Villalba, S. (2001). A phylogenetic framework for the aquaporin family in eukaryotes. J. Mol. Evol. 52, 391-404. doi: 10.1007/s002390010169.
    • (2001) J. Mol. Evol. , vol.52 , pp. 391-404
    • Zardoya, R.1    Villalba, S.2
  • 225
    • 79960481261 scopus 로고    scopus 로고
    • Mechanisms of membrane transport of folates into cells and across epithelia
    • doi: 10.1146/annurev-nutr-072610-145133
    • Zhao, R., Diop-Bove, N., Visentin, M., and Goldman, I. D. (2011). Mechanisms of membrane transport of folates into cells and across epithelia. Annu. Rev. Nutr. 31, 177-201. doi: 10.1146/annurev-nutr-072610-145133.
    • (2011) Annu. Rev. Nutr. , vol.31 , pp. 177-201
    • Zhao, R.1    Diop-Bove, N.2    Visentin, M.3    Goldman, I.D.4
  • 226
    • 0344393780 scopus 로고    scopus 로고
    • Resistance to antifolates
    • doi: 10.1038/sj.onc.1206946
    • Zhao, R., and Goldman, I. D. (2003). Resistance to antifolates. Oncogene 22, 7431-7457. doi: 10.1038/sj.onc.1206946.
    • (2003) Oncogene , vol.22 , pp. 7431-7457
    • Zhao, R.1    Goldman, I.D.2
  • 227
    • 82355175105 scopus 로고    scopus 로고
    • Reconstruction and analysis of human heart-specific metabolic network based on transcriptome and proteome data
    • doi: 10.1016/j.bbrc.2011.10.090
    • Zhao, Y., and Huang, J. (2011). Reconstruction and analysis of human heart-specific metabolic network based on transcriptome and proteome data. Biochem. Biophys. Res. Commun. 415, 450-454. doi: 10.1016/j.bbrc.2011.10.090.
    • (2011) Biochem. Biophys. Res. Commun. , vol.415 , pp. 450-454
    • Zhao, Y.1    Huang, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.