메뉴 건너뛰기




Volumn 213, Issue 2, 2006, Pages 67-77

Structure and function of cationic amino acid transporters (CATs)

Author keywords

Amino acid responsive element; Amino acid starvation; Cationic amino acid transporter; IRES; Micro RNA; Nitric oxide; Paraspeckles; SLC7; System y+

Indexed keywords

AMINO ACID TRANSPORTER; MESSENGER RNA;

EID: 34247245816     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-006-0875-7     Document Type: Review
Times cited : (203)

References (95)
  • 2
    • 0027532369 scopus 로고
    • Envelope-binding domain inthe cationic amino acid transporter determines the host range of ecotropic murineretroviruses
    • Albritton, L.M., Kim, J.W., Tseng, L., Cunningham, J.M. 1993b. Envelope-binding domain inthe cationic amino acid transporter determines the host range of ecotropic murineretroviruses. J. Virol. 67:2091-2096
    • (1993) J. Virol , vol.67 , pp. 2091-2096
    • Albritton, L.M.1    Kim, J.W.2    Tseng, L.3    Cunningham, J.M.4
  • 3
    • 0024370460 scopus 로고
    • A putative murine ecotropicretrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
    • Albritton, L.M., Tseng, L., Scadden, D., Cunningham, J.M. 1989. A putative murine ecotropicretrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57:659-666
    • (1989) Cell , vol.57 , pp. 659-666
    • Albritton, L.M.1    Tseng, L.2    Scadden, D.3    Cunningham, J.M.4
  • 4
    • 0037428464 scopus 로고    scopus 로고
    • Functional cooperation of epithelial heteromeric amino acid transporters expressed in madindarby canine kidney cells
    • Bauch, C., Forster, N., Loffing-Cueni, D., Summa, V., Verrey, F. 2003. Functional cooperation of epithelial heteromeric amino acid transporters expressed in madindarby canine kidney cells. J. Biol. Chem. 278:1316-1322
    • (2003) J. Biol. Chem , vol.278 , pp. 1316-1322
    • Bauch, C.1    Forster, N.2    Loffing-Cueni, D.3    Summa, V.4    Verrey, F.5
  • 5
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated translational repression in human cells subjected to stress
    • Bhattacharyya, S.N., Habermacher, R., Martine, U., Closs, E.I., Filipowicz, W. 2006. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125:1111-1124
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 6
    • 0029671006 scopus 로고    scopus 로고
    • Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cells
    • Bogle, R.G., Baydoun, A.R., Pearson, J.D., Mann, G.E. 1996. Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cells. J. Physiol. 490:229-241
    • (1996) J. Physiol , vol.490 , pp. 229-241
    • Bogle, R.G.1    Baydoun, A.R.2    Pearson, J.D.3    Mann, G.E.4
  • 8
    • 0034254798 scopus 로고    scopus 로고
    • The heterodimeric amino acid transporter4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine
    • Broer, A., Wagner, C.A., Lang, F., Broer, S. 2000. The heterodimeric amino acid transporter4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. Biochem. J. 349:787-795
    • (2000) Biochem. J , vol.349 , pp. 787-795
    • Broer, A.1    Wagner, C.A.2    Lang, F.3    Broer, S.4
  • 13
    • 0036140958 scopus 로고    scopus 로고
    • Expression, regulation and function of carrier proteins for cationic amino acids
    • Closs, E.I. 2002. Expression, regulation and function of carrier proteins for cationic amino acids. Curr. Opin. Nephrol. Hypertens. 11:99-107
    • (2002) Curr. Opin. Nephrol. Hypertens , vol.11 , pp. 99-107
    • Closs, E.I.1
  • 14
    • 0027409441 scopus 로고
    • Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver
    • Closs, E.I., Albritton, L.M., Kim, J.W., Cunningham, J.M. 1993a. Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver. J. Biol. Chem. 268:7538-7544
    • (1993) J. Biol. Chem , vol.268 , pp. 7538-7544
    • Closs, E.I.1    Albritton, L.M.2    Kim, J.W.3    Cunningham, J.M.4
  • 15
    • 0027411067 scopus 로고
    • Retroviral infection and expression of cationic amino acid transporters in rodent hepatocytes
    • Closs, E.I., Borel Rinkes, I.H., Bader, A., Yarmush, M.L., Cunningham, J.M. 1993b. Retroviral infection and expression of cationic amino acid transporters in rodent hepatocytes. J. Virol. 67:2097-2102
    • (1993) J. Virol , vol.67 , pp. 2097-2102
    • Closs, E.I.1    Borel Rinkes, I.H.2    Bader, A.3    Yarmush, M.L.4    Cunningham, J.M.5
  • 16
    • 0342506444 scopus 로고    scopus 로고
    • Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: Three related carriers with distinct transport properties
    • Closs, E.I., Gräf, P., Habermeier, A., Cunningham, J.M., Förstermann, U. 1997. Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: Three related carriers with distinct transport properties. Biochemistry 36:6462-6468
    • (1997) Biochemistry , vol.36 , pp. 6462-6468
    • Closs, E.I.1    Gräf, P.2    Habermeier, A.3    Cunningham, J.M.4    Förstermann, U.5
  • 17
    • 0027522050 scopus 로고
    • Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of adomain that determines the transport properties of the MCAT proteins
    • Closs, E.I., Lyons, C.R., Kelly, C., Cunningham, J.M. 1993c. Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of adomain that determines the transport properties of the MCAT proteins. J. Biol. Chem. 268:20796-20800
    • (1993) J. Biol. Chem , vol.268 , pp. 20796-20800
    • Closs, E.I.1    Lyons, C.R.2    Kelly, C.3    Cunningham, J.M.4
  • 18
    • 34247186639 scopus 로고    scopus 로고
    • Closs, E.I., Rotmann, A. 2005. Cationic amino acid transporter CAT-1 AfCS-Nature Molecule Pages:doi:10.1038/mp.a002772.01
    • Closs, E.I., Rotmann, A. 2005. Cationic amino acid transporter CAT-1 AfCS-Nature Molecule Pages:doi:10.1038/mp.a002772.01
  • 19
    • 4744356881 scopus 로고    scopus 로고
    • Plasma membrane transporters forarginine
    • discussion 2765S-2767S
    • Closs, E.I., Simon, A., Vekony, N., Rotmann, A. 2004. Plasma membrane transporters forarginine. J. Nutr. 134:2752S-2759S; discussion 2765S-2767S
    • (2004) J. Nutr , vol.134
    • Closs, E.I.1    Simon, A.2    Vekony, N.3    Rotmann, A.4
  • 20
    • 0027226002 scopus 로고
    • N-ethylmaleimide discriminates between two lysine transport systems in human erythrocytes
    • Deves, R., Angelo, S., Chavez, P. 1993. N-ethylmaleimide discriminates between two lysine transport systems in human erythrocytes. J. Physiol. 468:753-766
    • (1993) J. Physiol , vol.468 , pp. 753-766
    • Deves, R.1    Angelo, S.2    Chavez, P.3
  • 21
    • 0031916983 scopus 로고    scopus 로고
    • Transporters for cationic amino acids in animal cells: Discovery, structure, and function
    • Deves, R., Boyd, C.A. 1998. Transporters for cationic amino acids in animal cells: discovery, structure, and function. Physiol. Rev. 78:487-545
    • (1998) Physiol. Rev , vol.78 , pp. 487-545
    • Deves, R.1    Boyd, C.A.2
  • 22
    • 0026699334 scopus 로고
    • Identification of a new transport system (y+L) inhuman erythrocytes that recognizes lysine and leucine with high affinity
    • Deves, R., Chavez, P., Boyd, C.A. 1992. Identification of a new transport system (y+L) inhuman erythrocytes that recognizes lysine and leucine with high affinity. J. Physiol. Lond. 454:491-501
    • (1992) J. Physiol. Lond , vol.454 , pp. 491-501
    • Deves, R.1    Chavez, P.2    Boyd, C.A.3
  • 23
    • 15844397843 scopus 로고    scopus 로고
    • Platelet-derived growth factor regulates vascular smooth muscle cell proliferation by inducing cationic amino acid transporter gene expression
    • Durante, W., Liao, L., Iftikhar, I., Cheng, K., Schafer, A.I. 1996. Platelet-derived growth factor regulates vascular smooth muscle cell proliferation by inducing cationic amino acid transporter gene expression. J. Biol. Chem. 271:11838-11843
    • (1996) J. Biol. Chem , vol.271 , pp. 11838-11843
    • Durante, W.1    Liao, L.2    Iftikhar, I.3    Cheng, K.4    Schafer, A.I.5
  • 24
    • 0030830714 scopus 로고    scopus 로고
    • Lysophosphatidylcholine regulates cationic amino acid transport and metabolism in vascular smooth muscle cells. Role in polyamine biosynthesis
    • Durante, W., Liao, L., Peyton, K.J., Schafer, A.I. 1997. Lysophosphatidylcholine regulates cationic amino acid transport and metabolism in vascular smooth muscle cells. Role in polyamine biosynthesis. J. Biol. Chem. 272:30154-30159
    • (1997) J. Biol. Chem , vol.272 , pp. 30154-30159
    • Durante, W.1    Liao, L.2    Peyton, K.J.3    Schafer, A.I.4
  • 25
    • 0032572623 scopus 로고    scopus 로고
    • Thrombin stimulates vascular smooth muscle cell polyamine synthesis by inducing cationic amino acid transporter and ornithine decarboxylase gene expression
    • Durante, W., Liao, L., Peyton, K.J., Schafer, A.I. 1998. Thrombin stimulates vascular smooth muscle cell polyamine synthesis by inducing cationic amino acid transporter and ornithine decarboxylase gene expression. Circ. Res. 83:217-223
    • (1998) Circ. Res , vol.83 , pp. 217-223
    • Durante, W.1    Liao, L.2    Peyton, K.J.3    Schafer, A.I.4
  • 26
    • 0035957042 scopus 로고    scopus 로고
    • Transforming growth factor-beta(1) stimulates L-arginine transport and metabolism in vascular smooth muscle cells: Role in polyamine and collagen synthesis
    • Durante, W., Liao, L., Reyna, S.V., Peyton, K.J., Schafer, A.I. 2001. Transforming growth factor-beta(1) stimulates L-arginine transport and metabolism in vascular smooth muscle cells: role in polyamine and collagen synthesis. Circulation 103:1121-1127
    • (2001) Circulation , vol.103 , pp. 1121-1127
    • Durante, W.1    Liao, L.2    Reyna, S.V.3    Peyton, K.J.4    Schafer, A.I.5
  • 27
    • 0032821201 scopus 로고    scopus 로고
    • Feliubadalo, L., Font, M., Purroy, J., Rousaud, F., Estivill, X., Nunes, V., Golomb, E., Centola, M., Aksentijevich, I., Kreiss, Y., Goldman, B., Pras, M., Kastner, D.L., Pras, E., Gasparini, P., Bisceglia, L., Beccia, E., Gallucci, M., de Sanctis, L., Ponzone, A., Rizzoni, G.F., Zelante, L., Bassi, M.T., George, A.L., Manzoni, M., De Grandi, A., Riboni, M., Endsley, J.K., Ballabio, A., Borsani, G., Reig, N., Fernandez, E., Estevez, R., Pineda, M., Torrents, D., Camps, M., Lloberas, J., Zorzano, A., Palacin, M. 1999. Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b(o,+)AT)of rBAT. Nature Genetics. Sep. 23:52-57
    • Feliubadalo, L., Font, M., Purroy, J., Rousaud, F., Estivill, X., Nunes, V., Golomb, E., Centola, M., Aksentijevich, I., Kreiss, Y., Goldman, B., Pras, M., Kastner, D.L., Pras, E., Gasparini, P., Bisceglia, L., Beccia, E., Gallucci, M., de Sanctis, L., Ponzone, A., Rizzoni, G.F., Zelante, L., Bassi, M.T., George, A.L., Manzoni, M., De Grandi, A., Riboni, M., Endsley, J.K., Ballabio, A., Borsani, G., Reig, N., Fernandez, E., Estevez, R., Pineda, M., Torrents, D., Camps, M., Lloberas, J., Zorzano, A., Palacin, M. 1999. Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b(o,+)AT)of rBAT. Nature Genetics. Sep. 23:52-57
  • 28
    • 0037023688 scopus 로고    scopus 로고
    • Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner
    • Fernandez, J., Bode, B., Koromilas, A., Diehl, J.A., Krukovets, I., Snider, M.D., Hatzoglou, M. 2002a. Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner. J. Biol. Chem. 277:11780-11787
    • (2002) J. Biol. Chem , vol.277 , pp. 11780-11787
    • Fernandez, J.1    Bode, B.2    Koromilas, A.3    Diehl, J.A.4    Krukovets, I.5    Snider, M.D.6    Hatzoglou, M.7
  • 31
    • 0037127267 scopus 로고    scopus 로고
    • Regulation of internal ribosome entry site-mediated translation by eukaryotic initiation factor-2alpha phosphorylation and translation of a small upstream open reading frame
    • Fernandez, J., Yaman, I., Merrick, W.C., Koromilas, A., Wek, R.C., Sood, R., Hensold, J., Hatzoglou, M. 2002b. Regulation of internal ribosome entry site-mediated translation by eukaryotic initiation factor-2alpha phosphorylation and translation of a small upstream open reading frame. J. Biol. Chem. 277:2050-2058
    • (2002) J. Biol. Chem , vol.277 , pp. 2050-2058
    • Fernandez, J.1    Yaman, I.2    Merrick, W.C.3    Koromilas, A.4    Wek, R.C.5    Sood, R.6    Hensold, J.7    Hatzoglou, M.8
  • 32
    • 0035853762 scopus 로고    scopus 로고
    • Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability
    • Fernandez, J., Yaman, I., Mishra, R., Merrick, W.C., Snider, M.D., Lamers, W.H., Hatzoglou, M. 2001. Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability. J. Biol. Chem. 276:12285-12291
    • (2001) J. Biol. Chem , vol.276 , pp. 12285-12291
    • Fernandez, J.1    Yaman, I.2    Mishra, R.3    Merrick, W.C.4    Snider, M.D.5    Lamers, W.H.6    Hatzoglou, M.7
  • 33
    • 0037166289 scopus 로고    scopus 로고
    • Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha
    • Fernandez, J., Yaman, I., Sarnow, P., Snider, M.D., Hatzoglou, M. 2002c. Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha. J. Biol. Chem. 277:19198-205
    • (2002) J. Biol. Chem , vol.277 , pp. 19198-19205
    • Fernandez, J.1    Yaman, I.2    Sarnow, P.3    Snider, M.D.4    Hatzoglou, M.5
  • 34
    • 0037428211 scopus 로고    scopus 로고
    • Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium
    • Flores, C., Rojas, S., Aguayo, C., Parodi, J., Mann, G., Pearson, J.D., Casanello, P., Sobrevia, L. 2003. Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium. Circ. Res. 92:64-72
    • (2003) Circ. Res , vol.92 , pp. 64-72
    • Flores, C.1    Rojas, S.2    Aguayo, C.3    Parodi, J.4    Mann, G.5    Pearson, J.D.6    Casanello, P.7    Sobrevia, L.8
  • 35
    • 0015498961 scopus 로고
    • Regulation of amino acid transport in chick embryo heart cells. I. Adaptive system of mediation for neutral amino acids
    • Gazzola, G.C., Franchi, R., Saibene, V., Ronchi, P., Guidotti, G.G. 1972. Regulation of amino acid transport in chick embryo heart cells. I. Adaptive system of mediation for neutral amino acids. Biochim. Biophys. Acta. 266:407-421
    • (1972) Biochim. Biophys. Acta , vol.266 , pp. 407-421
    • Gazzola, G.C.1    Franchi, R.2    Saibene, V.3    Ronchi, P.4    Guidotti, G.G.5
  • 36
    • 3442882851 scopus 로고    scopus 로고
    • Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells
    • Gonzalez, M., Flores, C., Pearson, J.D., Casanello, P., Sobrevia, L. 2004. Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. Pfluegers Arch. 448:383-394
    • (2004) Pfluegers Arch , vol.448 , pp. 383-394
    • Gonzalez, M.1    Flores, C.2    Pearson, J.D.3    Casanello, P.4    Sobrevia, L.5
  • 37
    • 0035079905 scopus 로고    scopus 로고
    • The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C
    • Gräf, P., Förstermann, U., Closs, E.I. 2001. The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C. Br. J. Pharmacol. 132:1193-1200
    • (2001) Br. J. Pharmacol , vol.132 , pp. 1193-1200
    • Gräf, P.1    Förstermann, U.2    Closs, E.I.3
  • 38
    • 0038482085 scopus 로고    scopus 로고
    • Two amino acid residues determine the low substrate affinity of human cationic amino acid transporter-2A
    • Habermeier, A., Wolf, S., Martine, U., Graf, P., Closs, E.I. 2003. Two amino acid residues determine the low substrate affinity of human cationic amino acid transporter-2A. J. Biol. Chem. 278:19492-19499
    • (2003) J. Biol. Chem , vol.278 , pp. 19492-19499
    • Habermeier, A.1    Wolf, S.2    Martine, U.3    Graf, P.4    Closs, E.I.5
  • 39
    • 3142665989 scopus 로고    scopus 로고
    • Regulation of cationic amino acid transport: The story of the CAT-1 transporter
    • Hatzoglou, M., Fernandez, J., Yaman, I., Closs, E. 2004. Regulation of cationic amino acid transport: the story of the CAT-1 transporter. Annu. Rev. Nutr. 24:377-399
    • (2004) Annu. Rev. Nutr , vol.24 , pp. 377-399
    • Hatzoglou, M.1    Fernandez, J.2    Yaman, I.3    Closs, E.4
  • 41
    • 0030934701 scopus 로고    scopus 로고
    • Hosokawa, H., Sawamura, T., Kobayashi, S., Ninomiya, H., Miwa, S., Masaki, T. 1997. and characterization of a brain-specific cationic amino acid transporter. J. Biol. Chem. 272:8717-8722
    • Hosokawa, H., Sawamura, T., Kobayashi, S., Ninomiya, H., Miwa, S., Masaki, T. 1997. and characterization of a brain-specific cationic amino acid transporter. J. Biol. Chem. 272:8717-8722
  • 42
    • 0017304669 scopus 로고
    • Heterogeneity of histidine transport in the Ehrlich cell
    • Im, W.B., Christensen, H.N. 1976. Heterogeneity of histidine transport in the Ehrlich cell. Biochim. Biophys. Acta. 455:144151
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 144151
    • Im, W.B.1    Christensen, H.N.2
  • 43
    • 0030685798 scopus 로고    scopus 로고
    • A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain
    • Ito, K., Groudine, M. 1997. A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain. J. Biol. Chem. 272:26780-26786
    • (1997) J. Biol. Chem , vol.272 , pp. 26780-26786
    • Ito, K.1    Groudine, M.2
  • 44
    • 0036178037 scopus 로고    scopus 로고
    • Cationic amino acid transport in the renal medulla and blood pressure regulation
    • Kakoki, M., Wang, W., Mattson, D.L. 2002. Cationic amino acid transport in the renal medulla and blood pressure regulation. Hypertension 39:287-292
    • (2002) Hypertension , vol.39 , pp. 287-292
    • Kakoki, M.1    Wang, W.2    Mattson, D.L.3
  • 45
    • 0002686736 scopus 로고
    • + type cationic amino acid transport in Xenopus oocytes and show different tissue expression patterns
    • + type cationic amino acid transport in Xenopus oocytes and show different tissue expression patterns. Transgene 1:91-101
    • (1993) Transgene , vol.1 , pp. 91-101
    • Kakuda, D.K.1    Finley, K.D.2    Dionne, V.E.3    MacLeod, C.L.4
  • 46
    • 0032508859 scopus 로고    scopus 로고
    • Stress differentially induces cationic amino acid transporter gene expression
    • Kakuda, D.K., Finley, K.D., Maruyama, M., MacLeod, C.L. 1998. Stress differentially induces cationic amino acid transporter gene expression. Biochim. Biophys. Acta. 1414:75-84
    • (1998) Biochim. Biophys. Acta , vol.1414 , pp. 75-84
    • Kakuda, D.K.1    Finley, K.D.2    Maruyama, M.3    MacLeod, C.L.4
  • 47
    • 0027255645 scopus 로고
    • Voltage dependence of facilitated arginine flux mediated by the system y+ basic amino acid transporter
    • Kavanaugh, M.P. 1993. Voltage dependence of facilitated arginine flux mediated by the system y+ basic amino acid transporter. Biochemistry 32:5781-5785
    • (1993) Biochemistry , vol.32 , pp. 5781-5785
    • Kavanaugh, M.P.1
  • 48
    • 0028223722 scopus 로고
    • Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family
    • Kavanaugh, M.P., Wang, H., Zhang, Z., Zhang, W., Wu, Y.N., Dechant, E., North, R.A., Kabat, D. 1994. Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family. J. Biol. Chem. 269:15445-15450
    • (1994) J. Biol. Chem , vol.269 , pp. 15445-15450
    • Kavanaugh, M.P.1    Wang, H.2    Zhang, Z.3    Zhang, W.4    Wu, Y.N.5    Dechant, E.6    North, R.A.7    Kabat, D.8
  • 49
    • 0032583180 scopus 로고    scopus 로고
    • High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine
    • Kikuta, K., Sawamura, T., Miwa, S., Hashimoto, N., Masaki, T. 1998. High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine. Circ. Res. 83:1088-1096
    • (1998) Circ. Res , vol.83 , pp. 1088-1096
    • Kikuta, K.1    Sawamura, T.2    Miwa, S.3    Hashimoto, N.4    Masaki, T.5
  • 50
    • 0025784145 scopus 로고
    • Transport of cationic amino acids by the mouse ecotropic retrovirus receptor
    • Kim, J.W., Closs, E.I., Albritton, L.M., Cunningham, J.M. 1991. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 352:725-728
    • (1991) Nature , vol.352 , pp. 725-728
    • Kim, J.W.1    Closs, E.I.2    Albritton, L.M.3    Cunningham, J.M.4
  • 51
    • 0027261196 scopus 로고
    • N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells
    • Kim, J.W., Cunningham, J.M. 1993. N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells. J. Biol. Chem. 268:16316-16320
    • (1993) J. Biol. Chem , vol.268 , pp. 16316-16320
    • Kim, J.W.1    Cunningham, J.M.2
  • 52
    • 0036889315 scopus 로고    scopus 로고
    • System y+ localizes to different membrane subdomains in the basolateral plasma membrane of epithelial cells
    • Kizhatil, K., Albritton, L.M. 2002. System y+ localizes to different membrane subdomains in the basolateral plasma membrane of epithelial cells. Am. J. Physiol. 283:C1784-C1794
    • (2002) Am. J. Physiol , vol.283
    • Kizhatil, K.1    Albritton, L.M.2
  • 53
    • 0037834879 scopus 로고    scopus 로고
    • Classical isoforms of PKC as regulators ofCAT-1 transporter activity in pulmonary artery endothelial cells
    • Krotova, K.Y., Zharikov, S.I., Block, E.R. 2003. Classical isoforms of PKC as regulators ofCAT-1 transporter activity in pulmonary artery endothelial cells. Am. J. Physiol. 284:L1037-L1044
    • (2003) Am. J. Physiol , vol.284
    • Krotova, K.Y.1    Zharikov, S.I.2    Block, E.R.3
  • 54
    • 0033052051 scopus 로고    scopus 로고
    • Receptor-mediated Moloney murine leukemia virus entry can occur independently of the clathrin-coated-pit-mediated endocytic pathway
    • Lee, S., Zhao, Y., Anderson, W.F. 1999. Receptor-mediated Moloney murine leukemia virus entry can occur independently of the clathrin-coated-pit-mediated endocytic pathway. J. Virol. 73:5994-6005
    • (1999) J. Virol , vol.73 , pp. 5994-6005
    • Lee, S.1    Zhao, Y.2    Anderson, W.F.3
  • 55
    • 0034715520 scopus 로고    scopus 로고
    • Ecotropic murine leukemia virus receptor is physically associated with caveolin and membrane rafts
    • Lu, X., Silver, J. 2000. Ecotropic murine leukemia virus receptor is physically associated with caveolin and membrane rafts. Virology 276:251-258
    • (2000) Virology , vol.276 , pp. 251-258
    • Lu, X.1    Silver, J.2
  • 56
    • 0029791984 scopus 로고    scopus 로고
    • Regulation of cationic amino acid transporter (CAT) gene expression
    • MacLeod, C.L. 1996. Regulation of cationic amino acid transporter (CAT) gene expression. Biochem. Soc. Trans. 24:846-852
    • (1996) Biochem. Soc. Trans , vol.24 , pp. 846-852
    • MacLeod, C.L.1
  • 57
    • 0037207473 scopus 로고    scopus 로고
    • Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
    • Mann, G.E., Yudilevich, D.L., Sobrevia, L. 2003. Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells. Physiol. Rev. 83:183-252
    • (2003) Physiol. Rev , vol.83 , pp. 183-252
    • Mann, G.E.1    Yudilevich, D.L.2    Sobrevia, L.3
  • 58
    • 0344406171 scopus 로고    scopus 로고
    • CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes
    • Manner, C.K., Nicholson, B., MacLeod, C.L. 2003. CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes. J. Neurochem. 85:476-482
    • (2003) J. Neurochem , vol.85 , pp. 476-482
    • Manner, C.K.1    Nicholson, B.2    MacLeod, C.L.3
  • 59
    • 0032875453 scopus 로고    scopus 로고
    • Masuda, M., Kakushima, N., Wilt, S.G., Ruscetti, S.K., Hoffman, P.M., Iwamoto, A. 1999. of receptor usage by ecotropic murine retroviruses, using green fluorescent protein-tagged cationic amino acid transporters. J. Virol. 73:8623-8629
    • Masuda, M., Kakushima, N., Wilt, S.G., Ruscetti, S.K., Hoffman, P.M., Iwamoto, A. 1999. of receptor usage by ecotropic murine retroviruses, using green fluorescent protein-tagged cationic amino acid transporters. J. Virol. 73:8623-8629
  • 60
    • 0031452440 scopus 로고    scopus 로고
    • A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox
    • McDonald, K.K., Zharikov, S., Block, E.R., Kilberg, M.S. 1997. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox". J. Biol. Chem. 272:31213-31216
    • (1997) J. Biol. Chem , vol.272 , pp. 31213-31216
    • McDonald, K.K.1    Zharikov, S.2    Block, E.R.3    Kilberg, M.S.4
  • 61
    • 33644852813 scopus 로고    scopus 로고
    • Arginine: Beyond protein
    • Morris, S.M. Jr 2006. Arginine: beyond protein. Am. J. Clin. Nutr. 83:508S-512S
    • (2006) Am. J. Clin. Nutr , vol.83
    • Morris Jr, S.M.1
  • 62
    • 24944433410 scopus 로고    scopus 로고
    • Marrying immunotherapy with chemotherapy: Why say IDO?
    • Muller, A.J., Prendergast, G.C. 2005. Marrying immunotherapy with chemotherapy: why say IDO? Cancer. Res. 65:8065-8068
    • (2005) Cancer. Res , vol.65 , pp. 8065-8068
    • Muller, A.J.1    Prendergast, G.C.2
  • 63
    • 0035844305 scopus 로고    scopus 로고
    • Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
    • Nicholson, B., Manner, C.K., Kleeman, J., MacLeod, C.L. 2001. Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J. Biol. Chem. 276:15881-15885
    • (2001) J. Biol. Chem , vol.276 , pp. 15881-15885
    • Nicholson, B.1    Manner, C.K.2    Kleeman, J.3    MacLeod, C.L.4
  • 64
    • 0036433213 scopus 로고    scopus 로고
    • Cat2 L-arginine transporter-deficient fibroblasts can sustain nitric oxide production
    • Nicholson, B., Manner, C.K., MacLeod, C.L. 2002. Cat2 L-arginine transporter-deficient fibroblasts can sustain nitric oxide production. Nitric Oxide 7:236-243
    • (2002) Nitric Oxide , vol.7 , pp. 236-243
    • Nicholson, B.1    Manner, C.K.2    MacLeod, C.L.3
  • 65
    • 0032511020 scopus 로고    scopus 로고
    • Increased Cat3-mediated cationic amino acid transport functionally compensates in Cat1 knockout cell lines
    • Nicholson, B., Sawamura, T., Masaki, T., MacLeod, C.L. 1998. Increased Cat3-mediated cationic amino acid transport functionally compensates in Cat1 knockout cell lines. J. Biol. Chem. 273:14663-14666
    • (1998) J. Biol. Chem , vol.273 , pp. 14663-14666
    • Nicholson, B.1    Sawamura, T.2    Masaki, T.3    MacLeod, C.L.4
  • 66
    • 0037473291 scopus 로고    scopus 로고
    • Role of a conserved amino-terminal sequence in the ecotropic MLV receptor mCAT1
    • Ou, W., Silver, J. 2003. Role of a conserved amino-terminal sequence in the ecotropic MLV receptor mCAT1. Virology 308:101-113
    • (2003) Virology , vol.308 , pp. 101-113
    • Ou, W.1    Silver, J.2
  • 69
    • 0033521614 scopus 로고    scopus 로고
    • Amino acid transport of y(+)L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family
    • Pfeiffer, R., Rossier, G., Spindler, B., Meier, C., Kuhn, L., Verrey, F. 1999b. Amino acid transport of y(+)L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family. Embo. J. 18:49-57
    • (1999) Embo. J , vol.18 , pp. 49-57
    • Pfeiffer, R.1    Rossier, G.2    Spindler, B.3    Meier, C.4    Kuhn, L.5    Verrey, F.6
  • 71
    • 0032530551 scopus 로고    scopus 로고
    • Activation of L-arginine transport by protein kinase C in rabbit, rat and mouse alveolar macrophages
    • Racke, K., Hey, C., Mossner, J., Hammermann, R., Stichnote, C., Wessler, I. 1998. Activation of L-arginine transport by protein kinase C in rabbit, rat and mouse alveolar macrophages. J. Physiol. 511:813-825
    • (1998) J. Physiol , vol.511 , pp. 813-825
    • Racke, K.1    Hey, C.2    Mossner, J.3    Hammermann, R.4    Stichnote, C.5    Wessler, I.6
  • 73
    • 1642493659 scopus 로고    scopus 로고
    • Intracellular accumulation of L-Arg, kinetics of transport, and potassium leak conductance in oocytes from Xenopus laevis expressing hCAT-1, hCAT-2A, and hCAT-2B
    • Rotmann, A., Closs, E.I., Liewald, J.F., Nawrath, H. 2004a. Intracellular accumulation of L-Arg, kinetics of transport, and potassium leak conductance in oocytes from Xenopus laevis expressing hCAT-1, hCAT-2A, and hCAT-2B. Biochim. Biophys. Acta. 1660:138-143
    • (2004) Biochim. Biophys. Acta , vol.1660 , pp. 138-143
    • Rotmann, A.1    Closs, E.I.2    Liewald, J.F.3    Nawrath, H.4
  • 74
    • 11144228635 scopus 로고    scopus 로고
    • Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity
    • Rotmann, A., Strand, D., Martine, U., Closs, E.I. 2004b. Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity. J. Biol. Chem. 279:54185-54192
    • (2004) J. Biol. Chem , vol.279 , pp. 54185-54192
    • Rotmann, A.1    Strand, D.2    Martine, U.3    Closs, E.I.4
  • 75
    • 33645555687 scopus 로고    scopus 로고
    • Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane
    • Rotmann, A., Vekony, N., Gassner, D., Niegisch, G., Strand, D., Martine, U., Closs, E.I. 2006. Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane. Biochem. J. 395:117-123
    • (2006) Biochem. J , vol.395 , pp. 117-123
    • Rotmann, A.1    Vekony, N.2    Gassner, D.3    Niegisch, G.4    Strand, D.5    Martine, U.6    Closs, E.I.7
  • 76
    • 27944492352 scopus 로고    scopus 로고
    • Gestational diabetes and the adenosine/l-Arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium
    • San Martin, R., Sobrevia, L. 2006. Gestational diabetes and the adenosine/l-Arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium. Placenta 27:1-10
    • (2006) Placenta , vol.27 , pp. 1-10
    • San Martin, R.1    Sobrevia, L.2
  • 77
    • 0028822309 scopus 로고
    • Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: Association with membrane hyperpolarization
    • Sobrevia, L., Cesare, P., Yudilevich, D.L., Mann, G.E. 1995. Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarization. J. Physiol. 489:183-192
    • (1995) J. Physiol , vol.489 , pp. 183-192
    • Sobrevia, L.1    Cesare, P.2    Yudilevich, D.L.3    Mann, G.E.4
  • 78
    • 0031045689 scopus 로고    scopus 로고
    • Activation of A2-purinoceptors byadenosine stimulates L-arginine transport (system y+) and nitric oxide synthesis in human fetal endothelial cells
    • Sobrevia, L., Yudilevich, D.L., Mann, G.E. 1997. Activation of A2-purinoceptors byadenosine stimulates L-arginine transport (system y+) and nitric oxide synthesis in human fetal endothelial cells. J. Physiol. 499:135-140
    • (1997) J. Physiol , vol.499 , pp. 135-140
    • Sobrevia, L.1    Yudilevich, D.L.2    Mann, G.E.3
  • 79
    • 0032484216 scopus 로고    scopus 로고
    • Identification and characterization of a membrane protein (Y(+)L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y(+)L -A candidate gene for lysinuric protein intolerance
    • Torrents, D., Estevez, R., Pineda, M., Fernandez, E., Lloberas, J., Shi, Y.B., Zorzano, A., Palacin, M. 1998. Identification and characterization of a membrane protein (Y(+)L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y(+)L -A candidate gene for lysinuric protein intolerance. J. Biol. Chem. 273:32437-32445
    • (1998) J. Biol. Chem , vol.273 , pp. 32437-32445
    • Torrents, D.1    Estevez, R.2    Pineda, M.3    Fernandez, E.4    Lloberas, J.5    Shi, Y.B.6    Zorzano, A.7    Palacin, M.8
  • 80
    • 0023850572 scopus 로고
    • Na+- independent transport of basic and zwitterionic amino acids in mouse blastocytes by a shared system and by processes which distinguish between these substrates
    • Van Winkle, L.J., Campione, A.L., Gorman, J.M. 1988. Na+- independent transport of basic and zwitterionic amino acids in mouse blastocytes by a shared system and by processes which distinguish between these substrates. J. Biol. Chem. 263:3150-3163
    • (1988) J. Biol. Chem , vol.263 , pp. 3150-3163
    • Van Winkle, L.J.1    Campione, A.L.2    Gorman, J.M.3
  • 81
    • 0035899990 scopus 로고    scopus 로고
    • Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues
    • Vekony, N., Wolf, S., Boissel, J.P., Gnauert, K., Closs, E.I. 2001. Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry 40:12387-12394
    • (2001) Biochemistry , vol.40 , pp. 12387-12394
    • Vekony, N.1    Wolf, S.2    Boissel, J.P.3    Gnauert, K.4    Closs, E.I.5
  • 83
    • 0028086163 scopus 로고
    • A critical site in the cell surface receptor for ecotropic murine retroviruses required for amino acid transport but not for viral reception
    • Wang, H., Kavanaugh, M.P., Kabat, D. 1994. A critical site in the cell surface receptor for ecotropic murine retroviruses required for amino acid transport but not for viral reception. Virology 202:1058-1060
    • (1994) Virology , vol.202 , pp. 1058-1060
    • Wang, H.1    Kavanaugh, M.P.2    Kabat, D.3
  • 84
    • 0025734320 scopus 로고
    • Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter
    • Wang, H., Kavanaugh, M.P., North, R.A., Kabat, D. 1991. Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter. Nature 352:729-731
    • (1991) Nature , vol.352 , pp. 729-731
    • Wang, H.1    Kavanaugh, M.P.2    North, R.A.3    Kabat, D.4
  • 85
    • 0029820856 scopus 로고    scopus 로고
    • Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor amino acid transporter
    • Wang, H., Klamo, E., Kuhmann, S.E., Kozak, S.L., Kavanaugh, M.P., Kabat, D. 1996. Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor amino acid transporter. J. Virol. 70:6884-6891
    • (1996) J. Virol , vol.70 , pp. 6884-6891
    • Wang, H.1    Klamo, E.2    Kuhmann, S.E.3    Kozak, S.L.4    Kavanaugh, M.P.5    Kabat, D.6
  • 86
    • 0020419218 scopus 로고
    • The two-way flux of cationic amino acids across theplasma membrane of mammalian cells is largely explained by a single transport system
    • White, M.F., Christensen, H.N. 1982. The two-way flux of cationic amino acids across theplasma membrane of mammalian cells is largely explained by a single transport system. J. Biol. Chem. 257:10069-10080
    • (1982) J. Biol. Chem , vol.257 , pp. 10069-10080
    • White, M.F.1    Christensen, H.N.2
  • 87
    • 0020317553 scopus 로고
    • Cationic amino acid transport into cultured animal cells. I. Influx into cultured human fibroblasts
    • White, M.F., Gazzola, G.C., Christensen, H.N. 1982. Cationic amino acid transport into cultured animal cells. I. Influx into cultured human fibroblasts. J. Biol. Chem. 257:44439
    • (1982) J. Biol. Chem , vol.257 , pp. 44439
    • White, M.F.1    Gazzola, G.C.2    Christensen, H.N.3
  • 88
    • 0037097030 scopus 로고    scopus 로고
    • Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity
    • Wolf, S., Janzen, A., Vekony, N., Martine, U., Strand, D., Closs, E.I. 2002. Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. Biochem. J. 364:767-775
    • (2002) Biochem. J , vol.364 , pp. 767-775
    • Wolf, S.1    Janzen, A.2    Vekony, N.3    Martine, U.4    Strand, D.5    Closs, E.I.6
  • 89
    • 0028228944 scopus 로고
    • Plasma membrane clustering of system y(+) (CAT-1)amino acid transporter as detected by immunohistochemistry -Rapid communication
    • Woodard, M.H., Dunn, W.A., Laine, R.O., Malandro, M., Mcmahon, R., Simell, O., Block, E.R., Kilberg, M.S. 1994. Plasma membrane clustering of system y(+) (CAT-1)amino acid transporter as detected by immunohistochemistry -Rapid communication. Am. J. Physiol. 266:E817-E824
    • (1994) Am. J. Physiol , vol.266
    • Woodard, M.H.1    Dunn, W.A.2    Laine, R.O.3    Malandro, M.4    Mcmahon, R.5    Simell, O.6    Block, E.R.7    Kilberg, M.S.8
  • 91
    • 0036829750 scopus 로고    scopus 로고
    • Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR
    • Yaman, I., Fernandez, J., Sarkar, B., Schneider, R.J., Snider, M.D., Nagy, L.E., Hatzoglou, M. 2002. Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR. J. Biol. Chem. 277:41539-41546
    • (2002) J. Biol. Chem , vol.277 , pp. 41539-41546
    • Yaman, I.1    Fernandez, J.2    Sarkar, B.3    Schneider, R.J.4    Snider, M.D.5    Nagy, L.E.6    Hatzoglou, M.7
  • 92
    • 0025945418 scopus 로고
    • Molecular cloning and characterization of anovel human gene homologous to the murine ecotropic retroviral receptor
    • Yoshimoto, T., Yoshimoto, E., Meruelo, D. 1991. Molecular cloning and characterization of anovel human gene homologous to the murine ecotropic retroviral receptor. Virology 185:10-17
    • (1991) Virology , vol.185 , pp. 10-17
    • Yoshimoto, T.1    Yoshimoto, E.2    Meruelo, D.3
  • 93
    • 0033960571 scopus 로고    scopus 로고
    • Association of L-arginine transporters with fodrin: Implications for hypoxic inhibition of arginine uptake
    • Zharikov, S.I., Block, E.R. 2000. Association of L-arginine transporters with fodrin: implications for hypoxic inhibition of arginine uptake. Am. J. Physiol. 278:L111-L117
    • (2000) Am. J. Physiol , vol.278
    • Zharikov, S.I.1    Block, E.R.2
  • 94
    • 1942452756 scopus 로고    scopus 로고
    • Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-alpha activity
    • Zharikov, S.I., Krotova, K.Y., Belayev, L., Block, E.R. 2004. Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-alpha activity. Am. J. Physiol. 286:L974-L983
    • (2004) Am. J. Physiol , vol.286
    • Zharikov, S.I.1    Krotova, K.Y.2    Belayev, L.3    Block, E.R.4
  • 95
    • 0035000923 scopus 로고    scopus 로고
    • Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells
    • Zharikov, S.I., Sigova, A.A., Chen, S., Bubb, M.R., Block, E.R. 2001. Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells. Am. J. Physiol. 280:L465-L473
    • (2001) Am. J. Physiol , vol.280
    • Zharikov, S.I.1    Sigova, A.A.2    Chen, S.3    Bubb, M.R.4    Block, E.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.