-
1
-
-
0013843290
-
Uptake as a determinant of methotrexate response in mouse leukemias
-
Kessel D, Hall TC, Roberts D, Wodinsky I. Uptake as a determinant of methotrexate response in mouse leukemias. Science 1965;150:752-4.
-
(1965)
Science
, vol.150
, pp. 752-754
-
-
Kessel, D.1
Hall, T.C.2
Roberts, D.3
Wodinsky, I.4
-
2
-
-
0013877259
-
Relationship of phthalanilide-lipid complexes to uptake and retention of 2-chloro-40,4-di(2-imidazolin-2-yl)terephthalanilide (NSC 60339) by sensitive and resistant P388 leukemia cells
-
Yesair DW, Kohner FA, Rogers WI, Baronowsky PE, Kensler CJ. Relationship of phthalanilide-lipid complexes to uptake and retention of 2-chloro-40,4-di(2- imidazolin-2-yl)terephthalanilide (NSC 60339) by sensitive and resistant P388 leukemia cells. Cancer Res 1966;26:202-7.
-
(1966)
Cancer Res
, vol.26
, pp. 202-207
-
-
Yesair, D.W.1
Kohner, F.A.2
Rogers, W.I.3
Baronowsky, P.E.4
Kensler, C.J.5
-
3
-
-
0014290206
-
Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response
-
Kessel D, Botterill V, Wodinsky I. Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response. Cancer Res 1968;28:938-41.
-
(1968)
Cancer Res
, vol.28
, pp. 938-941
-
-
Kessel, D.1
Botterill, V.2
Wodinsky, I.3
-
4
-
-
0015893137
-
Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells
-
Dano K. Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells. Biochim Biophys Acta 1973;323:466-83.
-
(1973)
Biochim Biophys Acta
, vol.323
, pp. 466-483
-
-
Dano, K.1
-
5
-
-
30144435485
-
The genetics of ATP-binding cassette transporters
-
DOI 10.1016/S0076-6879(05)00024-8, PII S0076687905000248, 24, Phase II Conjugation Enzymes and Transport Systems
-
Dean M. The genetics of ATP-binding cassette transporters. Methods Enzymol 2005;400:409-29. (Pubitemid 43052434)
-
(2005)
Methods in Enzymology
, vol.400
, pp. 409-429
-
-
Dean, M.1
-
6
-
-
82955229539
-
The emergence of drug transporter-mediated multidrug resistance to cancer chemotherapy
-
Wu CP, Hsieh CH, Wu YS. The emergence of drug transporter-mediated multidrug resistance to cancer chemotherapy. Mol Pharm 2011.
-
(2011)
Mol Pharm
-
-
Wu, C.P.1
Hsieh, C.H.2
Wu, Y.S.3
-
7
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976;455:152-62.
-
(1976)
Biochim Biophys Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
8
-
-
0021288268
-
Amplificiation of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells
-
Roninson IB, Abelson HT, Housman DE, Howell N, Varshavsky A. Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells. Nature 1984;309:626-8. (Pubitemid 14106442)
-
(1984)
Nature
, vol.309
, Issue.5969
, pp. 626-628
-
-
Roninson, I.B.1
Abelson, H.T.2
Housman, D.E.3
-
9
-
-
0021797892
-
Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines
-
DOI 10.1038/316817a0
-
Riordan JR, Deuchars K, Kartner N, Alon N, Trent J, Ling V. Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 1985;316:817-9. (Pubitemid 15003740)
-
(1985)
Nature
, vol.316
, Issue.6031
, pp. 817-819
-
-
Riordan, J.R.1
Deuchars, K.2
Kartner, N.3
-
10
-
-
0022515908
-
Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells
-
Gros P, Croop J, Roninson I, Varshavsky A, Housman DE. Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells. Proc Natl Acad Sci U S A 1986;83:337-41. (Pubitemid 16080008)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.2
, pp. 337-341
-
-
Gros, P.1
Croop, J.2
Roninson, I.3
-
11
-
-
0022993652
-
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
-
Gros P, Croop J, Housman D. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 1986;47:371-80. (Pubitemid 17210151)
-
(1986)
Cell
, vol.47
, Issue.3
, pp. 371-380
-
-
Gros, P.1
Croop, J.2
Housman, D.3
-
12
-
-
0023006005
-
Isolation and expression of a complementary DNA that confers multidrug resistance
-
DOI 10.1038/323728a0
-
Gros P, Ben Neriah YB, Croop JM, Housman DE. Isolation and expression of a complementary DNA that confers multidrug resistance. Nature 1986;323:728-31. (Pubitemid 17172974)
-
(1986)
Nature
, vol.323
, Issue.6090
, pp. 728-731
-
-
Gros, P.1
Ben, N.Y.2
Croop, J.M.3
Housman, D.E.4
-
13
-
-
0022923890
-
The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein
-
DOI 10.1016/S0006-291X(86)80136-X
-
Ueda K, Cornwell MM, Gottesman MM, Pastan I, Roninson IB, Ling V, et al. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. Biochem Biophys Res Commun 1986;141:956-62. (Pubitemid 17006141)
-
(1986)
Biochemical and Biophysical Research Communications
, vol.141
, Issue.3
, pp. 956-962
-
-
Ueda, K.1
Cornwell, M.M.2
Gottesman, M.M.3
-
14
-
-
0344825356
-
P-glycoprotein: From genomics to mechanism
-
DOI 10.1038/sj.onc.1206948, Drug Resistance
-
Ambudkar SV, Kimchi-Sarfaty C, Sauna ZE, Gottesman MM. P-glycoprotein: from genomics to mechanism. Oncogene 2003;22:7468-85. (Pubitemid 37487170)
-
(2003)
Oncogene
, vol.22
, Issue.47 REV. ISS. 6
, pp. 7468-7485
-
-
Ambudkar, S.V.1
Kimchi-Sarfaty, C.2
Sauna, Z.E.3
Gottesman, M.M.4
-
16
-
-
65649131520
-
Multidrug resistance through the spectacle of P-glycoprotein
-
Goda K, Bacso Z, Szabo G. Multidrug resistance through the spectacle of P-glycoprotein. Curr Cancer Drug Targets 2009;9:281-97.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 281-297
-
-
Goda, K.1
Bacso, Z.2
Szabo, G.3
-
17
-
-
73949111398
-
Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation
-
Padowski JM, Pollack GM. Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation. Methods Mol Biol 2010;596:359-84.
-
(2010)
Methods Mol Biol
, vol.596
, pp. 359-384
-
-
Padowski, J.M.1
Pollack, G.M.2
-
18
-
-
80053561984
-
An update on ABCB1 pharmacogenetics: Insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics
-
Wolf SJ, Bachtiar M, Wang J, Sim TS, Chong SS, Lee CG. An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics. Pharmacogenomics J 2011;11:315-25.
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 315-325
-
-
Wolf, S.J.1
Bachtiar, M.2
Wang, J.3
Sim, T.S.4
Chong, S.S.5
Lee, C.G.6
-
19
-
-
0029820166
-
Characterization of the human ABC superfamily: Isolation and mapping of 21 new genes using the Expressed Sequence Tags database
-
Allikmets R, Gerrard B, Hutchinson A, Dean M. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum Mol Genet 1996;5:1649-55. (Pubitemid 26328884)
-
(1996)
Human Molecular Genetics
, vol.5
, Issue.10
, pp. 1649-1655
-
-
Allikmets, R.1
Gerrard, B.2
Hutchinson, A.3
Dean, M.4
-
20
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 1992;258:1650-4. (Pubitemid 23012438)
-
(1992)
Science
, vol.258
, Issue.5088
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.V.9
Deeley, R.G.10
-
21
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
DOI 10.1073/pnas.95.26.15665
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A 1998;95:15665-70. (Pubitemid 29018757)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.26
, pp. 15665-15670
-
-
Austin, D.L.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
22
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res 1998;58:5337-9. (Pubitemid 28551112)
-
(1998)
Cancer Research
, vol.58
, Issue.23
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
23
-
-
0032895533
-
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes
-
Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, et al. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Res 1999;59:8-13. (Pubitemid 29062946)
-
(1999)
Cancer Research
, vol.59
, Issue.1
, pp. 8-13
-
-
Miyake, K.1
Mickley, L.2
Litman, T.3
Zhan, Z.4
Robey, R.5
Cristensen, B.6
Brangi, M.7
Greenberger, L.8
Dean, M.9
Fojo, T.10
Bates, S.E.11
-
24
-
-
43149118341
-
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADMETox)
-
Szakacs G, Varadi A, Ozvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADMETox). Drug Discov Today 2008;13:379-93.
-
(2008)
Drug Discov Today
, vol.13
, pp. 379-393
-
-
Szakacs, G.1
Varadi, A.2
Ozvegy-Laczka, C.3
Sarkadi, B.4
-
25
-
-
0001607723
-
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
-
Walker JE, Saraste M, Runswick MJ, Gay NJ. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1982;1:945-51.
-
(1982)
EMBO J
, vol.1
, pp. 945-951
-
-
Walker, J.E.1
Saraste, M.2
Runswick, M.J.3
Gay, N.J.4
-
26
-
-
0022972654
-
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
-
Chen CJ, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM, et al. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 1986;47:381-9. (Pubitemid 17210152)
-
(1986)
Cell
, vol.47
, Issue.3
, pp. 381-389
-
-
Chen, C.-J.1
Chin, J.E.2
Ueda, K.3
-
27
-
-
0023019651
-
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
-
DOI 10.1038/324485a0
-
Gerlach JH, Endicott JA, Juranka PF, Henderson G, Sarangi F, Deuchars KL, et al. Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance. Nature 1986;324:485-9. (Pubitemid 17184171)
-
(1986)
Nature
, vol.324
, Issue.6096
, pp. 485-489
-
-
Gerlach, J.H.1
Endicott, J.A.2
Juranka, P.F.3
-
28
-
-
0022534951
-
A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria
-
Higgins CF, Hiles ID, Salmond GP, Gill DR, Downie JA, Evans IJ, et al. A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria. Nature 1986;323:448-50. (Pubitemid 16026272)
-
(1986)
Nature
, vol.323
, Issue.6087
, pp. 448-450
-
-
Higgins, C.F.1
Hiles, I.D.2
Salmond, G.P.C.3
-
29
-
-
0025374695
-
Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport
-
Hyde SC, Emsley P, Hartshorn MJ, Mimmack MM, Gileadi U, Pearce SR, et al. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature 1990;346:362-5.
-
(1990)
Nature
, vol.346
, pp. 362-365
-
-
Hyde, S.C.1
Emsley, P.2
Hartshorn, M.J.3
Mimmack, M.M.4
Gileadi, U.5
Pearce, S.R.6
-
30
-
-
33646566873
-
Membrane topology of the transporter associated with antigen processing (TAP1) within an assembled functional peptide-loading complex
-
DOI 10.1074/jbc.M509784200
-
Schrodt S, Koch J, Tampe R. Membrane topology of the transporter associated with antigen processing (TAP1) within an assembled functional peptide-loading complex. J Biol Chem 2006;281:6455-62. (Pubitemid 43847578)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.10
, pp. 6455-6462
-
-
Schrodt, S.1
Koch, J.2
Tampe, R.3
-
31
-
-
31844440738
-
Membrane topology of human ABC proteins
-
DOI 10.1016/j.febslet.2005.11.040, PII S0014579305014031, ABC Transporters
-
Tusnady GE, Sarkadi B, Simon I, Varadi A. Membrane topology of human ABC proteins. FEBS Lett 2006;580:1017-22. (Pubitemid 43185282)
-
(2006)
FEBS Letters
, vol.580
, Issue.4
, pp. 1017-1022
-
-
Tusnady, G.E.1
Sarkadi, B.2
Simon, I.3
Varadi, A.4
-
32
-
-
0026094617
-
Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily
-
Berkower C, Michaelis S. Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily. EMBO J 1991;10:3777-85. (Pubitemid 21905406)
-
(1991)
EMBO Journal
, vol.10
, Issue.12
, pp. 3777-3785
-
-
Berkower, C.1
Michaelis, S.2
-
33
-
-
0028229881
-
Reconstitution of drug-stimulated ATPase activity following co-expression of each half of human P-glycoprotein as separate polypeptides
-
Loo TW, Clarke DM. Reconstitution of drug-stimulated ATPase activity following co-expression of each half of human P-glycoprotein as separate polypeptides. J Biol Chem 1994;269:7750-5. (Pubitemid 24217990)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.10
, pp. 7750-7755
-
-
Loo, T.W.1
Clarke, D.M.2
-
34
-
-
0345583699
-
Both ATP sites of human P-glycoprotein are essential but not symmetric
-
DOI 10.1021/bi991115m
-
Hrycyna CA, Ramachandra M, Germann UA, Cheng PW, Pastan I, Gottesman MM. Both ATP sites of human P-glycoprotein are essential but not symmetric. Biochemistry 1999;38:13887-99. (Pubitemid 29504219)
-
(1999)
Biochemistry
, vol.38
, Issue.42
, pp. 13887-13899
-
-
Hrycyna, C.A.1
Ramachandra, M.2
Germann, U.A.3
Cheng, P.W.4
Pastan, I.5
Gottesman, M.M.6
-
35
-
-
23644433969
-
Exploring the minimal functional unit of the transporter associated with antigen processing
-
DOI 10.1016/j.febslet.2005.07.006, PII S0014579305008392
-
Koch J, Guntrum R, Tampe R. Exploring the minimal functional unit of the transporter associated with antigen processing. FEBS Lett 2005;579:4413-6. (Pubitemid 41116374)
-
(2005)
FEBS Letters
, vol.579
, Issue.20
, pp. 4413-4416
-
-
Koch, J.1
Guntrum, R.2
Tampe, R.3
-
36
-
-
0026593016
-
Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex
-
Kelly A, Powis SH, Kerr LA, Mockridge I, Elliott T, Bastin J, et al. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 1992;355:641-4.
-
(1992)
Nature
, vol.355
, pp. 641-644
-
-
Kelly, A.1
Powis, S.H.2
Kerr, L.A.3
Mockridge, I.4
Elliott, T.5
Bastin, J.6
-
37
-
-
0348111456
-
ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion
-
DOI 10.1074/jbc.M310223200
-
Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, et al. ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J Biol Chem 2003;278:48275-82. (Pubitemid 37523283)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 48275-48282
-
-
Graf, G.A.1
Yu, L.2
Li, W.-P.3
Gerard, R.4
Tuma, P.L.5
Cohen, J.C.6
Hobbs, H.H.7
-
38
-
-
3042635945
-
The mitochondrial ABC transporter Atm1p functions as a homodimer
-
DOI 10.1016/j.febslet.2004.05.051, PII S0014579304006593
-
Chloupkova M, Reaves SK, LeBard LM, Koeller DM. The mitochondrial ABC transporter Atm1p functions as a homodimer. FEBS Lett 2004;569:65-9. (Pubitemid 38844594)
-
(2004)
FEBS Letters
, vol.569
, Issue.1-3
, pp. 65-69
-
-
Chloupkova, M.1
Reaves, S.K.2
LeBard, L.M.3
Koeller, D.M.4
-
39
-
-
2442520293
-
Characterization of Oligomeric Human Half-ABC Transporter ATP-binding Cassette G2
-
DOI 10.1074/jbc.M310785200
-
Xu J, Liu Y, Yang Y, Bates S, Zhang JT. Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. J Biol Chem 2004;279:19781-89. (Pubitemid 38623417)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19781-19789
-
-
Xu, J.1
Liu, Y.2
Yang, Y.3
Bates, S.4
Zhang, J.-T.5
-
40
-
-
33749530252
-
Identification of a mammalian mitochondrial porphyrin transporter
-
DOI 10.1038/nature05125, PII NATURE05125
-
Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, et al. Identification of a mammalian mitochondrial porphyrin transporter. Nature 2006;443:586-9. (Pubitemid 44527295)
-
(2006)
Nature
, vol.443
, Issue.7111
, pp. 586-589
-
-
Krishnamurthy, P.C.1
Du, G.2
Fukuda, Y.3
Sun, D.4
Sampath, J.5
Mercer, K.E.6
Wang, J.7
Sosa-Pineda, B.8
Murti, K.G.9
Schuetz, J.D.10
-
41
-
-
77952567948
-
Structure of a human multidrug transporter in an inward-facing conformation
-
Rosenberg MF, Oleschuk CJ, Wu P, Mao Q, Deeley RG, Cole SP, et al. Structure of a human multidrug transporter in an inward-facing conformation. J Struct Biol 2010;170:540-7.
-
(2010)
J Struct Biol
, vol.170
, pp. 540-547
-
-
Rosenberg, M.F.1
Oleschuk, C.J.2
Wu, P.3
Mao, Q.4
Deeley, R.G.5
Cole, S.P.6
-
42
-
-
33748644877
-
Structure of a bacterial multidrug ABC transporter
-
DOI 10.1038/nature05155, PII NATURE05155
-
Dawson RJ, Locher KP. Structure of a bacterial multidrug ABC transporter. Nature 2006;443:180-5. (Pubitemid 44387602)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 180-185
-
-
Dawson, R.J.P.1
Locher, K.P.2
-
43
-
-
63449139456
-
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
-
Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, et al. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 2009;323:1718-22.
-
(2009)
Science
, vol.323
, pp. 1718-1722
-
-
Aller, S.G.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
-
44
-
-
0037342112
-
Deciphering the molecular basis of multidrug recognition: Crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR
-
DOI 10.1016/S0923-2508(02)00013-X
-
Schumacher MA, Brennan RG. Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. Res Microbiol 2003;154:69-77. (Pubitemid 36324497)
-
(2003)
Research in Microbiology
, vol.154
, Issue.2
, pp. 69-77
-
-
Schumacher, M.A.1
Brennan, R.G.2
-
45
-
-
0035801375
-
Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
-
DOI 10.1093/emboj/20.17.4964
-
Gaudet R, Wiley DC. Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J 2001;20:4964-72. (Pubitemid 32848648)
-
(2001)
EMBO Journal
, vol.20
, Issue.17
, pp. 4964-4972
-
-
Gaudet, R.1
Wiley, D.C.2
-
46
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
DOI 10.1016/S1097-2765(02)00576-2
-
Smith PC, Karpowich N, Millen L, Moody JE, Rosen J, Thomas PJ, et al. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol Cell 2002;10:139-49. (Pubitemid 34876568)
-
(2002)
Molecular Cell
, vol.10
, Issue.1
, pp. 139-149
-
-
Smith, P.C.1
Karpowich, N.2
Millen, L.3
Moody, J.E.4
Rosen, J.5
Thomas, P.J.6
Hunt, J.F.7
-
48
-
-
0032492724
-
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state
-
DOI 10.1021/bi973045u
-
Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, et al. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Biochemistry 1998;37:5010-9. (Pubitemid 28175983)
-
(1998)
Biochemistry
, vol.37
, Issue.14
, pp. 5010-5019
-
-
Ramachandra, M.1
Ambudkar, S.V.2
Chen, D.3
Hrycyna, C.A.4
Dey, S.5
Gottesman, M.M.6
Pastan, I.7
-
49
-
-
0032528075
-
Dissection of drug-binding-induced conformational changes in P-glycoprotein
-
DOI 10.1046/j.1432-1327.1998.2550383.x
-
Wang G, Pincheira R, Zhang JT. Dissection of drug-binding-induced conformational changes in P-glycoprotein. Eur J Biochem 1998;255:383-90. (Pubitemid 28340246)
-
(1998)
European Journal of Biochemistry
, vol.255
, Issue.2
, pp. 383-390
-
-
Wang, G.1
Pincheira, R.2
Zhang, J.-T.3
-
50
-
-
0035951073
-
The vinblastine binding site adopts high- and low-affinity conformations during a transport cycle of P-glycoprotein
-
DOI 10.1021/bi011211z
-
Martin C, Higgins CF, Callaghan R. The vinblastine binding site adopts high- and low-affinity conformations during a transport cycle of P-glycoprotein. Biochemistry 2001;40:15733-42. (Pubitemid 34015202)
-
(2001)
Biochemistry
, vol.40
, Issue.51
, pp. 15733-15742
-
-
Martin, C.1
Higgins, C.F.2
Callaghan, R.3
-
51
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
DOI 10.1016/0092-8674(94)90212-7
-
Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 1994;77:491-502. (Pubitemid 24153990)
-
(1994)
Cell
, vol.77
, Issue.4
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der, V.M.A.8
Robanus-Maandag, E.C.9
Te, R.H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
52
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma CC, Bosma PJ, Zaman GJ, Bakker CT, Otter M, Scheffer GL, et al. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science 1996;271:1126-8. (Pubitemid 26075228)
-
(1996)
Science
, vol.271
, Issue.5252
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.R.3
Bakker, C.T.M.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude, E.R.P.J.9
-
53
-
-
0033616684
-
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood- cerebrospinal-fluid drug-permeability barrier
-
DOI 10.1073/pnas.96.7.3900
-
Rao VV, Dahlheimer JL, Bardgett ME, Snyder AZ, Finch RA, Sartorelli AC, et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci U S A 1999;96:3900-5. (Pubitemid 29169008)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.7
, pp. 3900-3905
-
-
Rao, V.V.1
Dahlheimer, J.L.2
Bardgett, M.E.3
Snyder, A.Z.4
Finch, R.A.5
Sartorelli, A.C.6
Piwnica-Worms, D.7
-
54
-
-
0034684120
-
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
-
Jonker JW, Smit JW, Brinkhuis RF, Maliepaard M, Beijnen JH, Schellens JH, et al. Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. J Natl Cancer Inst 2000;92:1651-6.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1651-1656
-
-
Jonker, J.W.1
Smit, J.W.2
Brinkhuis, R.F.3
Maliepaard, M.4
Beijnen, J.H.5
Schellens, J.H.6
-
55
-
-
4344632950
-
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
-
DOI 10.1128/MCB.24.17.7612-7621.2004
-
Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, et al. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol Cell Biol 2004;24:7612-21. (Pubitemid 39121487)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.17
, pp. 7612-7621
-
-
Leggas, M.1
Adachi, M.2
Scheffer, G.L.3
Sun, D.4
Wielinga, P.5
Du, G.6
Mercer, K.E.7
Zhuang, Y.8
Panetta, J.C.9
Johnston, B.10
Scheper, R.J.11
Stewart, C.F.12
Schuetz, J.D.13
-
57
-
-
0018588082
-
Naturally occurring nucleoside and nucleotide antibiotics
-
Suhadolnik RJ. Naturally occurring nucleoside and nucleotide antibiotics. Prog Nucleic Acid Res Mol Biol 1979;22:193-291.
-
(1979)
Prog Nucleic Acid Res Mol Biol
, vol.22
, pp. 193-291
-
-
Suhadolnik, R.J.1
-
60
-
-
0014421568
-
Transport of two non-metabolized nucleosides, deoxycytidine and cytosine arabinoside, in a sub-line of the L1210 murine leukemia
-
Kessel D, Shurin SB. Transport of two non-metabolized nucleosides, deoxycytidine and cytosine arabinoside, in a sub-line of the L1210 murine leukemia. Biochim Biophys Acta 1968;163:179-87.
-
(1968)
Biochim Biophys Acta
, vol.163
, pp. 179-187
-
-
Kessel, D.1
Shurin, S.B.2
-
61
-
-
0015523073
-
Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants
-
Cass CE, Paterson AR. Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants. J Biol Chem 1972;247:3314-20.
-
(1972)
J Biol Chem
, vol.247
, pp. 3314-3320
-
-
Cass, C.E.1
Paterson, A.R.2
-
62
-
-
1242340323
-
The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins
-
DOI 10.1007/s00424-003-1192-y, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
-
Hediger MA, Romero MF, Peng JB, Rolfs A, Takanaga H, Bruford EA. The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins. Introduction. Pflugers Arch 2004;447:465-8. (Pubitemid 38241432)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.447
, Issue.5
, pp. 465-468
-
-
Hediger, M.A.1
Romero, M.F.2
Peng, J.-B.3
Rolfs, A.4
Takanaga, H.5
Bruford, E.A.6
-
63
-
-
0034995859
-
+-dependent nucleoside transporter (CNT) family: Identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)
-
Ritzel MW, Ng AM, Yao SY, Graham K, Loewen SK, Smith KM, et al. Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). Mol Membr Biol 2001;18:65-72. (Pubitemid 32521598)
-
(2001)
Molecular Membrane Biology
, vol.18
, Issue.1
, pp. 65-72
-
-
Ritzel, M.W.L.1
Ng, A.M.L.2
Yao, S.Y.M.3
Graham, K.4
Loewen, S.K.5
Smith, K.M.6
Hyde, R.J.7
Karpinski, E.8
Cass, C.E.9
Baldwin, S.A.10
Young, J.D.11
-
64
-
-
1242340288
-
The concentrative nucleoside transporter family, SLC28
-
DOI 10.1007/s00424-003-1107-y, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
-
Gray JH, Owen RP, Giacomini KM. The concentrative nucleoside transporter family, SLC28. Pflugers Arch 2004;447:728-34. (Pubitemid 38241458)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.447
, Issue.5
, pp. 728-734
-
-
Gray, J.H.1
Owen, R.P.2
Giacomini, K.M.3
-
65
-
-
0034995844
-
The ENT family of eukaryote nucleoside and nucleobase transporters: Recent advances in the investigation of structure/function relationships and the identification of novel isoforms
-
Hyde RJ, Cass CE, Young JD, Baldwin SA. The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol Membr Biol 2001;18:53-63. (Pubitemid 32521597)
-
(2001)
Molecular Membrane Biology
, vol.18
, Issue.1
, pp. 53-63
-
-
Hyde, R.J.1
Cass, C.E.2
Young, J.D.3
Baldwin, S.A.4
-
66
-
-
1242272722
-
The equilibrative nucleoside transporter family, SLC29
-
DOI 10.1007/s00424-003-1103-2, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
-
Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD. The equilibrative nucleoside transporter family, SLC29. Pflugers Arch 2004;447:735-43. (Pubitemid 38241459)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.447
, Issue.5
, pp. 735-743
-
-
Baldwin, S.A.1
Beal, P.R.2
Yao, S.Y.M.3
King, A.E.4
Cass, C.E.5
Young, J.D.6
-
67
-
-
0030938889
-
+-nucleoside cotransporter (hCNT1)
-
Ritzel MW, Yao SY, Huang MY, Elliott JF, Cass CE, Young JD. Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1). Am J Physiol 1997;272:C707-14. (Pubitemid 27142601)
-
(1997)
American Journal of Physiology - Cell Physiology
, vol.272
, Issue.2
-
-
Ritzel, M.W.L.1
Yao, S.Y.M.2
Huang, M.-Y.3
Elliott, J.F.4
Cass, C.E.5
Young, J.D.6
-
68
-
-
0032467105
-
+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine
-
Ritzel MW, Yao SY, Ng AM, Mackey JR, Cass CE, Young JD. Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine. Mol Membr Biol 1998;15:203-11. (Pubitemid 29097592)
-
(1998)
Molecular Membrane Biology
, vol.15
, Issue.4
, pp. 203-211
-
-
Ritzel, M.W.L.1
Yao, S.Y.M.2
Ng, A.M.L.3
Mackey, J.R.4
Cass, C.E.5
Young, J.D.6
-
69
-
-
0035951808
-
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)
-
Ritzel MW, Ng AM, Yao SY, Graham K, Loewen SK, Smith KM, et al. Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem 2001;276:2914-27.
-
(2001)
J Biol Chem
, vol.276
, pp. 2914-2927
-
-
Ritzel, M.W.1
Ng, A.M.2
Yao, S.Y.3
Graham, K.4
Loewen, S.K.5
Smith, K.M.6
-
70
-
-
0007844316
-
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs
-
DOI 10.1038/nm0197-89
-
Griffiths M, Beaumont N, Yao SY, Sundaram M, Boumah CE, Davies A, et al. Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med 1997;3:89-93. (Pubitemid 27019148)
-
(1997)
Nature Medicine
, vol.3
, Issue.1
, pp. 89-93
-
-
Griffiths, M.1
Beaumont, N.2
Yao, S.Y.M.3
Sundaram, M.4
Boumah, C.E.5
Davies, A.6
Kwong, F.Y.P.7
Coe, I.8
Cass, C.E.9
Young, J.D.10
Baldwin, S.A.11
-
71
-
-
0031439882
-
Molecular cloning and characterization of a nitrobenzylthioinosine- insensitive (ei) equilibrative nucleoside transporter from human placenta
-
Griffiths M, Yao SY, Abidi F, Phillips SE, Cass CE, Young JD, et al. Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem J 1997;328(Pt 3):739-43. (Pubitemid 28005769)
-
(1997)
Biochemical Journal
, vol.328
, Issue.3
, pp. 739-743
-
-
Griffiths, M.1
Yao, S.Y.M.2
Abidi, F.3
Phillips, S.E.V.4
Cass, C.E.5
Young, J.D.6
Baldwin, S.A.7
-
72
-
-
0031409587
-
Na(+)-dependent purine nucleoside transporter from human kidney: Cloning and functional characterization
-
Wang J, Su SF, Dresser MJ, Schaner ME, Washington CB, Giacomini KM. Na(+)-dependent purine nucleoside transporter from human kidney: cloning and functional characterization. Am J Physiol 1997;273:F1058-65.
-
(1997)
Am J Physiol
, vol.273
-
-
Wang, J.1
Su, S.F.2
Dresser, M.J.3
Schaner, M.E.4
Washington, C.B.5
Giacomini, K.M.6
-
73
-
-
0032570584
-
Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line
-
DOI 10.1074/jbc.273.9.5288
-
Crawford CR, Patel DH, Naeve C, Belt JA. Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line. J Biol Chem 1998;273:5288-93. (Pubitemid 28108694)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.9
, pp. 5288-5293
-
-
Crawford, C.R.1
Patel, D.H.2
Naeve, C.3
Belt, J.A.4
-
74
-
-
0037565518
-
Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1
-
DOI 10.1097/00008571-200305000-00010
-
Osato DH, Huang CC, Kawamoto M, Johns SJ, Stryke D, Wang J, et al. Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1. Pharmacogenetics 2003;13:297-301. (Pubitemid 36583998)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.5
, pp. 297-301
-
-
Osato, D.H.1
Huang, C.C.2
Kawamoto, M.3
Johns, S.J.4
Stryke, D.5
Wang, J.6
Ferrin, T.E.7
Herskowitz, I.8
Giacomini, K.M.9
-
75
-
-
33748999014
-
Thirty novel genetic variations in the SLC29A1 gene encoding human equilibrative nucleoside transporter 1 (hENT1)
-
Kim SR, Saito Y, Maekawa K, Sugiyama E, Kaniwa N, Ueno H, et al. Thirty novel genetic variations in the SLC29A1 gene encoding human equilibrative nucleoside transporter 1 (hENT1). Drug Metab Pharmacokinet 2006;21:248-56.
-
(2006)
Drug Metab Pharmacokinet
, vol.21
, pp. 248-256
-
-
Kim, S.R.1
Saito, Y.2
Maekawa, K.3
Sugiyama, E.4
Kaniwa, N.5
Ueno, H.6
-
76
-
-
48749099279
-
Organic cation transporters
-
Ciarimboli G. Organic cation transporters. Xenobiotica 2008;38:936-71.
-
(2008)
Xenobiotica
, vol.38
, pp. 936-971
-
-
Ciarimboli, G.1
-
77
-
-
63849083391
-
Transport of lamivudine [(-)-beta-L-2′,3′-dideoxy-3′- thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3
-
Minuesa G, Volk C, Molina-Arcas M, Gorboulev V, Erkizia I, Arndt P, et al. Transport of lamivudine [(-)-beta-L-2′,3′-dideoxy-3′- thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3. J Pharmacol Exp Ther 2009;329:252-61.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 252-261
-
-
Minuesa, G.1
Volk, C.2
Molina-Arcas, M.3
Gorboulev, V.4
Erkizia, I.5
Arndt, P.6
-
78
-
-
75349105185
-
Organic anion transporters: Discovery, pharmacology, regulation and roles in pathophysiology
-
VanWert AL, Gionfriddo MR, Sweet DH. Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology. Biopharm Drug Dispos 2010;31:1-71.
-
(2010)
Biopharm Drug Dispos
, vol.31
, pp. 1-71
-
-
VanWert, A.L.1
Gionfriddo, M.R.2
Sweet, D.H.3
-
79
-
-
0025890427
-
Metabolism and action of purine nucleoside analogs
-
Plunkett W, Saunders PP. Metabolism and action of purine nucleoside analogs. Pharmacol Ther 1991;49:239-68.
-
(1991)
Pharmacol Ther
, vol.49
, pp. 239-268
-
-
Plunkett, W.1
Saunders, P.P.2
-
80
-
-
0036636579
-
Nucleoside analogues and nucleobases in cancer treatment
-
DOI 10.1016/S1470-2045(02)00788-X
-
Galmarini CM, Mackey JR, Dumontet C. Nucleoside analogues and nucleobases in cancer treatment. Lancet Oncol 2002;3:415-24. (Pubitemid 36958272)
-
(2002)
Lancet Oncology
, vol.3
, Issue.7
, pp. 415-424
-
-
Galmarini, C.M.1
Mackey, J.R.2
Dumontet, C.3
-
81
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
DOI 10.1038/nrc1074
-
Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330-8. (Pubitemid 37328853)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
82
-
-
0019131198
-
Correlation of cytotoxicity with incorporation of ara-C into DNA
-
Kufe DW, Major PP, Egan EM, Beardsley GP. Correlation of cytotoxicity with incorporation of ara-C into DNA. J Biol Chem 1980;255:8997-9900.
-
(1980)
J Biol Chem
, vol.255
, pp. 8997-9900
-
-
Kufe, D.W.1
Major, P.P.2
Egan, E.M.3
Beardsley, G.P.4
-
83
-
-
0025233649
-
Incorporation of 2-halogeno-2′-deoxyadenosine 5-triphosphates into DNA during replication by human polymerases alpha and beta
-
Hentosh P, Koob R, Blakley RL. Incorporation of 2-halogeno-2′- deoxyadenosine 5-triphosphates into DNA during replication by human polymerases alpha and beta. J Biol Chem 1990;265:4033-40.
-
(1990)
J Biol Chem
, vol.265
, pp. 4033-4040
-
-
Hentosh, P.1
Koob, R.2
Blakley, R.L.3
-
84
-
-
0026324313
-
Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
-
Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W. Action of 2′,2′-difluorodeoxycytidine on DNA synthesis. Cancer Res 1991;51:6110-7.
-
(1991)
Cancer Res
, vol.51
, pp. 6110-6117
-
-
Huang, P.1
Chubb, S.2
Hertel, L.W.3
Grindey, G.B.4
Plunkett, W.5
-
85
-
-
0027180521
-
2',2'-difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines
-
DOI 10.1016/0006-2952(93)90566-F
-
Ruiz van Haperen VW, Veerman G, Vermorken JB, Peters GJ. 2′,2′-Difluorodeoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines. Biochem Pharmacol 1993;46:762-6. (Pubitemid 23262974)
-
(1993)
Biochemical Pharmacology
, vol.46
, Issue.4
, pp. 762-766
-
-
Ruiz, V.H.V.W.T.1
Veerman, G.2
Vermorken, J.B.3
Peters, G.J.4
-
86
-
-
0023733094
-
Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase
-
Parker WB, Bapat AR, Shen JX, Townsend AJ, Cheng YC. Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase. Mol Pharmacol 1988;34:485-91.
-
(1988)
Mol Pharmacol
, vol.34
, pp. 485-491
-
-
Parker, W.B.1
Bapat, A.R.2
Shen, J.X.3
Townsend, A.J.4
Cheng, Y.C.5
-
87
-
-
0025077195
-
Metabolism and action of fludarabine phosphate
-
Plunkett W, Huang P, Gandhi V. Metabolism and action of fludarabine phosphate. Semin Oncol 1990;17:3-17. (Pubitemid 20356424)
-
(1990)
Seminars in Oncology
, vol.17
, Issue.5 SUPPL. 8
, pp. 3-17
-
-
Plunkett, W.1
Huang, P.2
Gandhi, V.3
-
88
-
-
67649410242
-
Treating childhood acute lymphoblastic leukemia without cranial irradiation
-
Pui CH, Campana D, Pei D, Bowman WP, Sandlund JT, Kaste SC, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009;360:2730-41.
-
(2009)
N Engl J Med
, vol.360
, pp. 2730-2741
-
-
Pui, C.H.1
Campana, D.2
Pei, D.3
Bowman, W.P.4
Sandlund, J.T.5
Kaste, S.C.6
-
89
-
-
9144222570
-
Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia
-
DOI 10.1182/blood-2003-06-2122
-
Jeha S, Gandhi V, Chan KW, McDonald L, Ramirez I, Madden R, et al. Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia. Blood 2004;103:784-9. (Pubitemid 38129533)
-
(2004)
Blood
, vol.103
, Issue.3
, pp. 784-789
-
-
Jeha, S.1
Gandhi, V.2
Chan, K.W.3
McDonald, L.4
Ramirez, I.5
Madden, R.6
Rytting, M.7
Brandt, M.8
Keating, M.9
Plunkett, W.10
Kantarjian, H.11
-
90
-
-
33745294373
-
High-dose cytosine arabinoside in the treatment of acute myeloid leukemia: Review of three randomized trials
-
DOI 10.1002/cncr.21543
-
Kern W, Estey EH. High-dose cytosine arabinoside in the treatment of acute myeloid leukemia: review of three randomized trials. Cancer 2006;107:116-24. (Pubitemid 43939038)
-
(2006)
Cancer
, vol.107
, Issue.1
, pp. 116-124
-
-
Kern, W.1
Estey, E.H.2
-
91
-
-
0032409839
-
Expression of deoxycytidine kinase (dCK) gene in leukemic cells in childhood: Decreased expression of dCK gene in relapsed leukemia
-
Kakihara T, Fukuda T, Tanaka A, Emura I, Kishi K, Asami K, et al. Expression of deoxycytidine kinase (dCK) gene in leukemic cells in childhood: decreased expression of dCK gene in relapsed leukemia. Leuk Lymphoma 1998;31:405-9. (Pubitemid 29033962)
-
(1998)
Leukemia and Lymphoma
, vol.31
, Issue.3-4
, pp. 405-409
-
-
Kakihara, T.1
Fukuda, T.2
Tanaka, A.3
Emura, I.4
Kishi, K.5
Asami, K.6
Uchiyama, M.7
-
92
-
-
0037333569
-
Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver
-
DOI 10.1016/S0959-8049(02)00813-4
-
van der Wilt CL, Kroep JR, Loves WJ, Rots MG, Van Groeningen CJ, Kaspers GJ, et al. Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver. Eur J Cancer 2003;39:691-7. (Pubitemid 36287383)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.5
, pp. 691-697
-
-
Van Der, W.C.L.1
Kroep, J.R.2
Loves, W.J.P.3
Rots, M.G.4
Van Groeningen, C.J.5
Kaspers, G.J.6
Peters, G.J.7
-
93
-
-
36348945304
-
Pharmacogenetics of deoxycytidine kinase: Identification and characterization of novel genetic variants
-
DOI 10.1124/jpet.107.128595
-
Lamba JK, Crews K, Pounds S, Schuetz EG, Gresham J, Gandhi V, et al. Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants. J Pharmacol Exp Ther 2007;323:935-45. (Pubitemid 350146062)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.323
, Issue.3
, pp. 935-945
-
-
Lamba, J.K.1
Crews, K.2
Pounds, S.3
Schuetz, E.G.4
Gresham, J.5
Gandhi, V.6
Plunkett, W.7
Rubnitz, J.8
Ribeiro, R.9
-
94
-
-
0019808979
-
Identification of the mechanism of activation of 9-beta-D- arabinofuranosyladenine in human lymphoid cells using mutants deficient in nucleoside kinases
-
Verhoef V, Sarup J, Fridland A. Identification of the mechanism of activation of 9-beta-D-arabinofuranosyladenine in human lymphoid cells using mutants deficient in nucleoside kinases. Cancer Res 1981;41:4478-83. (Pubitemid 12201361)
-
(1981)
Cancer Research
, vol.41
, Issue.11 I
, pp. 4478-4483
-
-
Verhoef, V.1
Sarup, J.2
Fridland, A.3
-
95
-
-
0033406797
-
Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line
-
Mansson E, Spasokoukotskaja T, Sallstrom J, Eriksson S, Albertioni F. Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line. Cancer Res 1999;59:5956-63. (Pubitemid 30004957)
-
(1999)
Cancer Research
, vol.59
, Issue.23
, pp. 5956-5963
-
-
Mansson, E.1
Spasokoukotskaja, T.2
Sallstrom, J.3
Eriksson, S.4
Albertioni, F.5
-
96
-
-
42049091651
-
Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells
-
DOI 10.1158/0008-5472.CAN-07-5528
-
Cai J, Damaraju VL, Groulx N, Mowles D, Peng Y, Robins MJ, et al. Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells. Cancer Res 2008;68:2349-57. (Pubitemid 351521809)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2349-2357
-
-
Cai, J.1
Damaraju, V.L.2
Groulx, N.3
Mowles, D.4
Peng, Y.5
Robins, M.J.6
Cass, C.E.7
Gros, P.8
-
97
-
-
0018357475
-
Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques
-
Bowen D, Diasio RB, Goldman ID. Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques. J Biol Chem 1979;254:5333-9. (Pubitemid 9231898)
-
(1979)
Journal of Biological Chemistry
, vol.254
, Issue.12
, pp. 5333-5339
-
-
Bowen, D.1
Diasio, R.B.2
Goldman, I.D.3
-
98
-
-
0021025261
-
Alteration of the pharmacokinetics of high-dose Ara-C by its metabolite, high Ara-U in patients with acute leukemia
-
Capizzi RL, Yang JL, Cheng E, Bjornsson T, Sahasrabudhe D, Tan RS, et al. Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia. J Clin Oncol 1983;1:763-71. (Pubitemid 14167250)
-
(1983)
Journal of Clinical Oncology
, vol.1
, Issue.12
, pp. 763-771
-
-
Capizzi, R.L.1
Yong, J.-L.2
Cheng, E.3
-
99
-
-
0032879904
-
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
-
DOI 10.1038/12487
-
Schuetz JD, Connelly MC, Sun D, Paibir SG, Flynn PM, Srinivas RV, et al. MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med 1999;5:1048-51. (Pubitemid 29439577)
-
(1999)
Nature Medicine
, vol.5
, Issue.9
, pp. 1048-1051
-
-
Schuetz, J.D.1
Connelly, M.C.2
Sun, D.3
Paibir, S.G.4
Flynn, P.M.5
Srinivas, R.V.6
Kumar, A.7
Fridland, A.8
-
100
-
-
0028937676
-
A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent
-
Robbins BL, Connelly MC, Marshall DR, Srinivas RV, Fridland A. A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent. Mol Pharmacol 1995;47:391-7.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 391-397
-
-
Robbins, B.L.1
Connelly, M.C.2
Marshall, D.R.3
Srinivas, R.V.4
Fridland, A.5
-
101
-
-
0017807188
-
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells
-
Alt FW, Kellems RE, Bertino JR, Schimke RT. Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. J Biol Chem 1978;253:1357-70. (Pubitemid 8303433)
-
(1978)
Journal of Biological Chemistry
, vol.253
, Issue.5
, pp. 1357-1370
-
-
Alt, F.W.1
Kellems, R.E.2
Bertino, J.R.3
Schimke, R.T.4
-
102
-
-
0018263636
-
Gene amplification and drug resistance in cultured murine cells
-
Schimke RT, Kaufman RJ, Alt FW, Kellems RF. Gene amplification and drug resistance in cultured murine cells. Science 1978;202:1051-5.
-
(1978)
Science
, vol.202
, pp. 1051-1055
-
-
Schimke, R.T.1
Kaufman, R.J.2
Alt, F.W.3
Kellems, R.F.4
-
103
-
-
0021363699
-
Gene amplification, drug resistance, and cancer
-
Schimke RT. Gene amplification, drug resistance, and cancer. Cancer Res 1984;44:1735-42. (Pubitemid 14145705)
-
(1984)
Cancer Research
, vol.44
, Issue.5
, pp. 1735-1742
-
-
Schimke, R.T.1
-
104
-
-
0035823559
-
Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
-
Chen ZS, Lee K, Kruh GD. Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J Biol Chem 2001;276:33747-54.
-
(2001)
J Biol Chem
, vol.276
, pp. 33747-33754
-
-
Chen, Z.S.1
Lee, K.2
Kruh, G.D.3
-
105
-
-
0036893815
-
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells
-
DOI 10.1124/mol.62.6.1321
-
Wielinga PR, Reid G, Challa EE, van der Heijden I, van Deemter L, de Haas M, et al. Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Mol Pharmacol 2002;62:1321-31. (Pubitemid 35407456)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.6
, pp. 1321-1331
-
-
Wielinga, P.R.1
Reid, G.2
Challa, E.E.3
Van Der, H.I.4
Van Deemter, L.5
De Haas, M.6
Mol, C.7
Kuil, A.J.8
Groeneveld, E.9
Schuetz, J.D.10
Brouwer, C.11
De Abreu, R.A.12
Wijnholds, J.13
Beijnen, J.H.14
Borst, P.15
-
106
-
-
40049109204
-
Up-regulation of MRP4 and down-regulation of influx transporters in human leukemic cells with acquired resistance to 6-mercaptopurine
-
DOI 10.1016/j.leukres.2007.09.015, PII S0145212607003542
-
Peng XX, Shi Z, Damaraju VL, Huang XC, Kruh GD, Wu HC, et al. Upregulation of MRP4 and down-regulation of influx transporters in human leukemic cells with acquired resistance to 6-mercaptopurine. Leuk Res 2008;32:799-809. (Pubitemid 351323936)
-
(2008)
Leukemia Research
, vol.32
, Issue.5
, pp. 799-809
-
-
Peng, X.-X.1
Shi, Z.2
Damaraju, V.L.3
Huang, X.-C.4
Kruh, G.D.5
Wu, H.-C.6
Zhou, Y.7
Tiwari, A.8
Fu, L.9
Cass, C.E.10
Chen, Z.-S.11
-
107
-
-
52449097584
-
Role of MRP4 and MRP5 in biology and chemotherapy
-
Sampath J, Adachi M, Hatse S, Naesens L, Balzarini J, Flatley RM, et al. Role of MRP4 and MRP5 in biology and chemotherapy. AAPS PharmSci 2002;4:E14.
-
(2002)
AAPS PharmSci
, vol.4
-
-
Sampath, J.1
Adachi, M.2
Hatse, S.3
Naesens, L.4
Balzarini, J.5
Flatley, R.M.6
-
108
-
-
12944270590
-
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
-
DOI 10.1073/pnas.120159197
-
Wijnholds J, Mol CA, van Deemter L, de Haas M, Scheffer GL, Baas F, et al. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. Proc Natl Acad Sci U S A 2000;97:7476-81. (Pubitemid 30431488)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.13
, pp. 7476-7481
-
-
Wijnholds, J.1
Mol, C.A.A.M.2
Van Deemter, L.3
De Haas, M.4
Scheffer, G.L.5
Baas, F.6
Beijnen, J.H.7
Scheper, R.J.8
Hatse, S.9
De Clercq, E.10
Balzarini, J.11
Borst, P.12
-
109
-
-
0038752694
-
Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5
-
DOI 10.1124/mol.63.5.1094
-
Reid G, Wielinga P, Zelcer N, De Haas M, Van Deemter L, Wijnholds J, et al. Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. Mol Pharmacol 2003;63:1094-103. (Pubitemid 36529928)
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.5
, pp. 1094-1103
-
-
Reid, G.1
Wielinga, P.2
Zelcer, N.3
De Haas, M.4
Van Deemter, L.5
Wijnholds, J.6
Balzarini, J.7
Borst, P.8
-
110
-
-
20044383925
-
The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
-
DOI 10.1158/1535-7163.MCT-04-0291
-
Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry 3rd W, Dantzig AH. The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 2005;4:855-63. (Pubitemid 40767130)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.5
, pp. 855-863
-
-
Pratt, S.1
Shepard, R.L.2
Kandasamy, R.A.3
Johnston, P.A.4
Perry III, W.5
Dantzig, A.H.6
-
111
-
-
33748306343
-
The determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: A role of ABCC5 in gemcitabine sensitivity
-
DOI 10.1158/1535-7163.MCT-06-0025
-
Oguri T, Achiwa H, Sato S, Bessho Y, Takano Y, Miyazaki M, et al. The determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: a role of ABCC5 in gemcitabine sensitivity. Mol Cancer Ther 2006;5:1800-6. (Pubitemid 44323248)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.7
, pp. 1800-1806
-
-
Oguri, T.1
Achiwa, H.2
Sato, S.3
Bessho, Y.4
Takano, Y.5
Miyazaki, M.6
Muramatsu, H.7
Maeda, H.8
Niimi, T.9
Ueda, R.10
-
112
-
-
0042531890
-
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′- dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine
-
DOI 10.1074/jbc.M304059200
-
Guo Y, Kotova E, Chen ZS, Lee K, Hopper-Borge E, Belinsky MG, et al. MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine. J Biol Chem 2003;278:29509-14. (Pubitemid 36962331)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.32
, pp. 29509-29514
-
-
Guo, Y.1
Kotova, E.2
Chen, Z.-S.3
Lee, K.4
Hopper-Borge, E.5
Belinsky, M.G.6
Kruh, G.D.7
-
113
-
-
33846826935
-
MRP8/ABCC11 directly confers resistance to 5-fluorouracil
-
DOI 10.1158/1535-7163.MCT-06-0529
-
Oguri T, Bessho Y, Achiwa H, Ozasa H, Maeno K, Maeda H, et al. MRP8/ABCC11 directly confers resistance to 5-fluorouracil. Mol Cancer Ther 2007;6:122-7. (Pubitemid 46206674)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.1
, pp. 122-127
-
-
Oguri, T.1
Bessho, Y.2
Achiwa, H.3
Ozasa, H.4
Maeno, K.5
Maeda, H.6
Sato, S.7
Ueda, R.8
-
114
-
-
63449093153
-
Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: Relation to long-term survival
-
Guo Y, Kock K, Ritter CA, Chen ZS, Grube M, Jedlitschky G, et al. Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival. Clin Cancer Res 2009;15:1762-9.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1762-1769
-
-
Guo, Y.1
Kock, K.2
Ritter, C.A.3
Chen, Z.S.4
Grube, M.5
Jedlitschky, G.6
-
115
-
-
58249103864
-
Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B
-
Hopper-Borge E, Xu X, Shen T, Shi Z, Chen ZS, Kruh GD. Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B. Cancer Res 2009;69:178-84.
-
(2009)
Cancer Res
, vol.69
, pp. 178-184
-
-
Hopper-Borge, E.1
Xu, X.2
Shen, T.3
Shi, Z.4
Chen, Z.S.5
Kruh, G.D.6
-
116
-
-
33845999250
-
cGMP transport by vesicles from human and mouse erythrocytes
-
DOI 10.1111/j.1742-4658.2006.05591.x
-
de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, et al. cGMP transport by vesicles from human and mouse erythrocytes. FEBS J 2007;274:439-50. (Pubitemid 46046653)
-
(2007)
FEBS Journal
, vol.274
, Issue.2
, pp. 439-450
-
-
De Wolf, C.J.F.1
Yamaguchi, H.2
Van Der, H.I.3
Wielinga, P.R.4
Hundscheid, S.L.5
Ono, N.6
Scheffer, G.L.7
De Haas, M.8
Schuetz, J.D.9
Wijnholds, J.10
Borst, P.11
-
117
-
-
34547114499
-
Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution
-
DOI 10.1158/0008-5472.CAN-06-4720
-
Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, et al. Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer Res 2007;67:6965-72. (Pubitemid 47105544)
-
(2007)
Cancer Research
, vol.67
, Issue.14
, pp. 6965-6972
-
-
Takenaka, K.1
Morgan, J.A.2
Scheffer, G.L.3
Adachi, M.4
Stewart, C.F.5
Sun, D.6
Leggas, M.7
Ejendal, K.F.K.8
Hrycyna, C.A.9
Schuetz, J.D.10
-
118
-
-
54049137262
-
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides
-
de Wolf C, Jansen R, Yamaguchi H, de Haas M, van de Wetering K, Wijnholds J, et al. Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides. Mol Cancer Ther 2008;7:3092-102.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3092-3102
-
-
De Wolf, C.1
Jansen, R.2
Yamaguchi, H.3
De Haas, M.4
Van De Wetering, K.5
Wijnholds, J.6
-
119
-
-
79952210590
-
Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity
-
Nagai S, Takenaka K, Nachagari D, Rose C, Domoney K, Sun D, et al. Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity. Cancer Res 2011;71:1781-91.
-
(2011)
Cancer Res
, vol.71
, pp. 1781-1791
-
-
Nagai, S.1
Takenaka, K.2
Nachagari, D.3
Rose, C.4
Domoney, K.5
Sun, D.6
-
120
-
-
0036052296
-
BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia
-
Steinbach D, Sell W, Voigt A, Hermann J, Zintl F, Sauerbrey A. BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia. Leukemia 2002;16:1443-7.
-
(2002)
Leukemia
, vol.16
, pp. 1443-1447
-
-
Steinbach, D.1
Sell, W.2
Voigt, A.3
Hermann, J.4
Zintl, F.5
Sauerbrey, A.6
-
121
-
-
9744264044
-
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias
-
DOI 10.1158/1078-0432.CCR-04-0795
-
Benderra Z, Faussat AM, Sayada L, Perrot JY, Chaoui D, Marie JP, et al. Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias. Clin Cancer Res 2004;10:7896-902. (Pubitemid 39587528)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.23
, pp. 7896-7902
-
-
Benderra, Z.1
Faussat, A.-M.2
Sayada, L.3
Perrot, J.-Y.4
Chaoui, D.5
Marie, J.-P.6
Legrand, O.7
-
122
-
-
33745957993
-
Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction
-
DOI 10.1182/blood-2004-12-4633
-
Wilson CS, Davidson GS, Martin SB, Andries E, Potter J, Harvey R, et al. Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction. Blood 2006;108:685-96. (Pubitemid 44061371)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 685-696
-
-
Wilson, C.S.1
Davidson, G.S.2
Martin, S.B.3
Andries, E.4
Potter, J.5
Harvey, R.6
Ar, K.7
Xu, Y.8
Kopecky, K.J.9
Ankerst, D.P.10
Gundacker, H.11
Slovak, M.L.12
Mosquera-Caro, M.13
Chen, I.-M.14
Stirewalt, D.L.15
Murphy, M.16
Schultz, F.A.17
Kang, H.18
Wang, X.19
Radich, J.P.20
Appelbaum, F.R.21
Atlas, S.R.22
Godwin, J.23
Willman, C.L.24
more..
-
123
-
-
77952911036
-
Fludarabine-based induction therapy does not overcome the negative effect of ABCG2 (BCRP) over-expression in adult acute myeloid leukemia patients
-
Damiani D, Tiribelli M, Michelutti A, Geromin A, Cavallin M, Fabbro D, et al. Fludarabine-based induction therapy does not overcome the negative effect of ABCG2 (BCRP) over-expression in adult acute myeloid leukemia patients. Leuk Res 2010;34:942-5.
-
(2010)
Leuk Res
, vol.34
, pp. 942-945
-
-
Damiani, D.1
Tiribelli, M.2
Michelutti, A.3
Geromin, A.4
Cavallin, M.5
Fabbro, D.6
-
124
-
-
0035884595
-
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
-
Honjo Y, Hrycyna CA, Yan QW, Medina-Perez WY, Robey RW, van de Laar A, et al. Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells. Cancer Res 2001;61:6635-9. (Pubitemid 32896477)
-
(2001)
Cancer Research
, vol.61
, Issue.18
, pp. 6635-6639
-
-
Honjo, Y.1
Hrycyna, C.A.2
Yan, Q.-W.3
Medina-Perez, W.Y.4
Robey, R.W.5
Van De, L.A.6
Litman, T.7
Dean, M.8
Bates, S.E.9
-
125
-
-
0037246432
-
Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine
-
DOI 10.1097/00008571-200301000-00004
-
Zamber CP, Lamba JK, Yasuda K, Farnum J, Thummel K, Schuetz JD, et al. Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. Pharmacogenetics 2003;13:19-28. (Pubitemid 36135683)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.1
, pp. 19-28
-
-
Zamber, C.P.1
Lamba, J.K.2
Yasuda, K.3
Farnum, J.4
Thummel, K.5
Schuetz, J.D.6
Schuetz, E.G.7
-
126
-
-
48549088791
-
Transporter-mediated protection against thiopurine-induced hematopoietic toxicity
-
Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, et al. Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. Cancer Res 2008;68:4983-9.
-
(2008)
Cancer Res
, vol.68
, pp. 4983-4989
-
-
Krishnamurthy, P.1
Schwab, M.2
Takenaka, K.3
Nachagari, D.4
Morgan, J.5
Leslie, M.6
-
127
-
-
78249243846
-
The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease
-
Ban H, Andoh A, Imaeda H, Kobori A, Bamba S, Tsujikawa T, et al. The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease. J Gastroenterol 2010;45:1014-21.
-
(2010)
J Gastroenterol
, vol.45
, pp. 1014-1021
-
-
Ban, H.1
Andoh, A.2
Imaeda, H.3
Kobori, A.4
Bamba, S.5
Tsujikawa, T.6
-
128
-
-
0034213588
-
ABC-me: A novel mitochondrial transporter induced by GATA-1 during erythroid differentiation
-
Shirihai OS, Gregory T, Yu C, Orkin SH, Weiss MJ. ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J 2000;19:2492-502. (Pubitemid 30323539)
-
(2000)
EMBO Journal
, vol.19
, Issue.11
, pp. 2492-2502
-
-
Shirihai, O.S.1
Gregory, T.2
Yu, C.3
Orkin, S.H.4
Weiss, M.J.5
-
129
-
-
0034953105
-
The human ATP-binding cassette (ABC) transporter superfamily
-
Dean M, Hamon Y, Chimini G. The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 2001;42:1007-17. (Pubitemid 32645780)
-
(2001)
Journal of Lipid Research
, vol.42
, Issue.7
, pp. 1007-1017
-
-
Dean, M.1
Hamon, Y.2
Chimini, G.3
-
130
-
-
7944226987
-
Association of ABCA2 expression with determinants of Alzheimer's disease
-
DOI 10.1096/fj.03-1490fje
-
Chen ZJ, Vulevic B, Ile KE, Soulika A, Davis Jr W, Reiner PB, et al. Association of ABCA2 expression with determinants of Alzheimer's disease. FASEB J 2004;18:1129-31. (Pubitemid 39561546)
-
(2004)
FASEB Journal
, vol.18
, Issue.10
, pp. 1129-1131
-
-
Chen, Z.J.1
Vulevic, B.2
Ile, K.E.3
Soulika, A.4
Davis Jr., W.5
Reiner, P.B.6
Connop, B.P.7
Nathwani, P.8
Trojanowski, J.Q.9
Tew, K.D.10
-
131
-
-
33846678695
-
The ABCA subfamily - Gene and protein structures, functions and associated hereditary diseases
-
DOI 10.1007/s00424-006-0047-8, 20 years of ABC transporters
-
Albrecht C, Viturro E. The ABCA subfamily-gene and protein structures, functions and associated hereditary diseases. Pflugers Arch 2007;453:581-9. (Pubitemid 46192531)
-
(2007)
Pflugers Archiv European Journal of Physiology
, vol.453
, Issue.5
, pp. 581-589
-
-
Albrecht, C.1
Viturro, E.2
-
132
-
-
33846664466
-
ATP-binding cassette, subfamily G (ABCG family)
-
DOI 10.1007/s00424-006-0134-x, 20 years of ABC transporters
-
Kusuhara H, Sugiyama Y. ATP-binding cassette, subfamily G (ABCG family). Pflugers Arch 2007;453:735-44. (Pubitemid 46192543)
-
(2007)
Pflugers Archiv European Journal of Physiology
, vol.453
, Issue.5
, pp. 735-744
-
-
Kusuhara, H.1
Sugiyama, Y.2
-
133
-
-
70350100345
-
Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma
-
Chen KG, Valencia JC, Gillet JP, Hearing VJ, Gottesman MM. Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma. Pigment Cell Melanoma Res 2009;22:740-9.
-
(2009)
Pigment Cell Melanoma Res
, vol.22
, pp. 740-749
-
-
Chen, K.G.1
Valencia, J.C.2
Gillet, J.P.3
Hearing, V.J.4
Gottesman, M.M.5
-
134
-
-
84856364427
-
Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children
-
Flamein F, Riffault L, Muselet-Charlier C, Pernelle J, Feldmann D, Jonard L, et al. Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children. Hum Mol Genet 2011.
-
(2011)
Hum Mol Genet
-
-
Flamein, F.1
Riffault, L.2
Muselet-Charlier, C.3
Pernelle, J.4
Feldmann, D.5
Jonard, L.6
-
135
-
-
79957737791
-
Mammalian peroxisomal ABC transporters: From endogenous substrates to pathology and clinical significance
-
Kemp S, Theodoulou FL, Wanders RJ. Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance. Br J Pharmacol 2011;164:1753-66.
-
(2011)
Br J Pharmacol
, vol.164
, pp. 1753-1766
-
-
Kemp, S.1
Theodoulou, F.L.2
Wanders, R.J.3
-
136
-
-
80052509365
-
The lipid translocase, ABCA4: Seeing is believing
-
Pollock NL, Callaghan R. The lipid translocase, ABCA4: seeing is believing. FEBS J 2011;278:3204-14.
-
(2011)
FEBS J
, vol.278
, pp. 3204-3214
-
-
Pollock, N.L.1
Callaghan, R.2
|