메뉴 건너뛰기




Volumn 7, Issue , 2010, Pages

Role of carnitine in disease

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; CARNITINE; CARNITINE PALMITOYLTRANSFERASE I; CYCLOSPORIN A; VALPROIC ACID;

EID: 77950837764     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-7-30     Document Type: Review
Times cited : (459)

References (168)
  • 1
    • 0022478915 scopus 로고
    • Carnitine: An overview of its role in preventive medicine
    • 10.1016/0091-7435(86)90005-8. 3532087
    • Carnitine: an overview of its role in preventive medicine. BS Kendler, Prev Med 1986 15 373 390 10.1016/0091-7435(86)90005-8 3532087
    • (1986) Prev Med , vol.15 , pp. 373-390
    • Kendler, B.S.1
  • 2
    • 0025561023 scopus 로고
    • Primary and secondary disorders of carnitine metabolism
    • Primary and secondary disorders of carnitine metabolism. DC De Vivo I Tein, Int Pediatr 1990 5 8
    • (1990) Int Pediatr , vol.5 , pp. 8
    • De Vivo, D.C.1    Tein, I.2
  • 3
    • 10644229056 scopus 로고    scopus 로고
    • Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism
    • 10.1196/annals.1320.003. 15591001
    • Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. CJ Rebouche, Ann N Y Acad Sci 2004 1033 30 41 10.1196/annals.1320.003 15591001
    • (2004) Ann N y Acad Sci , vol.1033 , pp. 30-41
    • Rebouche, C.J.1
  • 4
    • 0025765643 scopus 로고
    • Metabolic fate of dietary carnitine in human adults: Identification and quantification of urinary and fecal metabolites
    • 2007906
    • Metabolic fate of dietary carnitine in human adults: identification and quantification of urinary and fecal metabolites. CJ Rebouche CA Chenard, J Nutr 1991 121 539 546 2007906
    • (1991) J Nutr , vol.121 , pp. 539-546
    • Rebouche, C.J.1    Chenard, C.A.2
  • 6
    • 0027049235 scopus 로고
    • Carnitine function and requirements during the life cycle
    • 1464372
    • Carnitine function and requirements during the life cycle. CJ Rebouche, Faseb J 1992 6 3379 3386 1464372
    • (1992) Faseb J , vol.6 , pp. 3379-3386
    • Rebouche, C.J.1
  • 7
    • 0024313361 scopus 로고
    • Carnitine status of lactoovovegetarians and strict vegetarian adults and children
    • 2756917
    • Carnitine status of lactoovovegetarians and strict vegetarian adults and children. KA Lombard AL Olson SE Nelson CJ Rebouche, Am J Clin Nutr 1989 50 301 306 2756917
    • (1989) Am J Clin Nutr , vol.50 , pp. 301-306
    • Lombard, K.A.1    Olson, A.L.2    Nelson, S.E.3    Rebouche, C.J.4
  • 8
    • 0036471216 scopus 로고    scopus 로고
    • Carnitine biosynthesis in mammals
    • 10.1042/0264-6021:3610417. 11802770
    • Carnitine biosynthesis in mammals. FM Vaz RJ Wanders, Biochem J 2002 361 417 429 10.1042/0264-6021:3610417 11802770
    • (2002) Biochem J , vol.361 , pp. 417-429
    • Vaz, F.M.1    Wanders, R.J.2
  • 9
    • 35548994282 scopus 로고    scopus 로고
    • Philadelphia: Lippincott, Williams and Wilkins Shils M, Shike M, Ross A, et al
    • C Rebouche, Carnitine: Modern Nutrition in Health and Disease Philadelphia: Lippincott, Williams and Wilkins, Shils M, Shike M, Ross A, et al, 2006 537 544
    • (2006) Carnitine: Modern Nutrition in Health and Disease , pp. 537-544
    • Rebouche, C.1
  • 10
    • 0023156622 scopus 로고
    • Clinical varieties of carnitine and carnitine palmitoyltransferase deficiency
    • 10.1016/S0009-9120(87)80090-5. 3552320
    • Clinical varieties of carnitine and carnitine palmitoyltransferase deficiency. C Angelini C Trevisan G Isaya G Pegolo L Vergani, Clin Biochem 1987 20 1 7 10.1016/S0009-9120(87)80090-5 3552320
    • (1987) Clin Biochem , vol.20 , pp. 1-7
    • Angelini, C.1    Trevisan, C.2    Isaya, G.3    Pegolo, G.4    Vergani, L.5
  • 12
    • 0031816464 scopus 로고    scopus 로고
    • Carnitine metabolism and its regulation in microorganisms and mammals
    • 10.1146/annurev.nutr.18.1.39. 9706218
    • Carnitine metabolism and its regulation in microorganisms and mammals. CJ Rebouche H Seim, Annu Rev Nutr 1998 18 39 61 10.1146/annurev.nutr.18.1.39 9706218
    • (1998) Annu Rev Nutr , vol.18 , pp. 39-61
    • Rebouche, C.J.1    Seim, H.2
  • 13
    • 0035345349 scopus 로고    scopus 로고
    • L-carnitine in dialysis patients
    • 10.1046/j.1525-139X.2001.00055.x. 11422928
    • L-carnitine in dialysis patients. S Ahmad, Semin Dial 2001 14 209 217 10.1046/j.1525-139X.2001.00055.x 11422928
    • (2001) Semin Dial , vol.14 , pp. 209-217
    • Ahmad, S.1
  • 14
    • 36148956147 scopus 로고    scopus 로고
    • Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+)
    • 10.1152/ajpgi.00233.2007. 17855766
    • Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). SR Srinivas PD Prasad NS Umapathy V Ganapathy PS Shekhawat, Am J Physiol Gastrointest Liver Physiol 2007 293 1046 1053 10.1152/ajpgi.00233.2007 17855766
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293 , pp. 71046-1053
    • Srinivas, S.R.1    Prasad, P.D.2    Umapathy, N.S.3    Ganapathy, V.4    Shekhawat, P.S.5
  • 15
    • 77951938654 scopus 로고
    • Current concepts in carnitine research
    • Current Concepts in Carnitine Research. GD Lopaschuk, Atlanta 1991
    • (1991) Atlanta
    • Lopaschuk, G.D.1
  • 16
    • 0025101871 scopus 로고
    • Carnitine deficiency syndromes
    • 10.1016/0887-8994(90)90037-2. 2187442
    • Carnitine deficiency syndromes. GN Breningstall, Pediatr Neurol 1990 6 75 81 10.1016/0887-8994(90)90037-2 2187442
    • (1990) Pediatr Neurol , vol.6 , pp. 75-81
    • Breningstall, G.N.1
  • 17
    • 0037044281 scopus 로고    scopus 로고
    • Exercise tolerance in carnitine palmitoyltransferase II deficiency with IV and oral glucose
    • 10.1001/archneur.59.6.1046. 12370460
    • Exercise tolerance in carnitine palmitoyltransferase II deficiency with IV and oral glucose. MC Orngreen DB Olsen J Vissing, Neurology 2002 59 1046 1051 10.1001/archneur.59.6.1046 12370460
    • (2002) Neurology , vol.59 , pp. 1046-1051
    • Orngreen, M.C.1    Olsen, D.B.2    Vissing, J.3
  • 18
    • 63649123163 scopus 로고    scopus 로고
    • Turning down lipid oxidation during heavy exercise - What is the mechanism?
    • 19258655
    • Turning down lipid oxidation during heavy exercise - what is the mechanism? K Sahlin EK Sallstedt D Bishop M Tonkonogi, J Physiol Pharmacol 2008 59 Suppl 7 19 30 19258655
    • (2008) J Physiol Pharmacol , vol.59 , Issue.SUPPL 7 , pp. 19-30
    • Sahlin, K.1    Sallstedt, E.K.2    Bishop, D.3    Tonkonogi, M.4
  • 19
    • 0033764847 scopus 로고    scopus 로고
    • Carnitine: An osmolyte that plays a metabolic role
    • 10.1002/1097-4644(20010101)80:1<1::AID-JCB10>3.0.CO;2-W. 11029749
    • Carnitine: an osmolyte that plays a metabolic role. G Peluso A Barbarisi V Savica E Reda R Nicolai P Benatti M Calvani, J Cell Biochem 2000 80 1 10 10.1002/1097-4644(20010101)80:1<1::AID-JCB10>3.0.CO;2-W 11029749
    • (2000) J Cell Biochem , vol.80 , pp. 1-10
    • Peluso, G.1    Barbarisi, A.2    Savica, V.3    Reda, E.4    Nicolai, R.5    Benatti, P.6    Calvani, M.7
  • 21
    • 0033517087 scopus 로고    scopus 로고
    • Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: A novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality
    • 10.1006/bbrc.1999.1060. 10425211
    • Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: a novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality. B Burwinkel J Kreuder S Schweitzer M Vorgerd K Gempel KD Gerbitz MW Kilimann, Biochem Biophys Res Commun 1999 261 484 487 10.1006/bbrc.1999.1060 10425211
    • (1999) Biochem Biophys Res Commun , vol.261 , pp. 484-487
    • Burwinkel, B.1    Kreuder, J.2    Schweitzer, S.3    Vorgerd, M.4    Gempel, K.5    Gerbitz, K.D.6    Kilimann, M.W.7
  • 23
    • 38149012408 scopus 로고    scopus 로고
    • L-carnitine supplementation in the dialysis population: Are Australian patients missing out?
    • 18199095
    • L-carnitine supplementation in the dialysis population: are Australian patients missing out? SE Reuter RJ Faull AM Evans, Nephrology (Carlton) 2008 13 3 16 18199095
    • (2008) Nephrology (Carlton) , vol.13 , pp. 3-16
    • Reuter, S.E.1    Faull, R.J.2    Evans, A.M.3
  • 24
    • 0036432303 scopus 로고    scopus 로고
    • Carnitine membrane transporter deficiency: A long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency
    • 10.1016/S1096-7192(02)00169-5. 12409266
    • Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency. SD Cederbaum S Koo-McCoy I Tein BY Hsu A Ganguly E Vilain K Dipple L Cvitanovic-Sojat C Stanley, Mol Genet Metab 2002 77 195 201 10.1016/S1096- 7192(02)00169-5 12409266
    • (2002) Mol Genet Metab , vol.77 , pp. 195-201
    • Cederbaum, S.D.1    Koo-Mccoy, S.2    Tein, I.3    Hsu, B.Y.4    Ganguly, A.5    Vilain, E.6    Dipple, K.7    Cvitanovic-Sojat, L.8    Stanley, C.9
  • 25
    • 0142151107 scopus 로고    scopus 로고
    • Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2
    • 10.1023/A:1025968502527. 14605509
    • Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2. U Spiekerkoetter G Huener T Baykal M Demirkol M Duran R Wanders J Nezu E Mayatepek, J Inherit Metab Dis 2003 26 613 615 10.1023/A:1025968502527 14605509
    • (2003) J Inherit Metab Dis , vol.26 , pp. 613-615
    • Spiekerkoetter, U.1    Huener, G.2    Baykal, T.3    Demirkol, M.4    Duran, M.5    Wanders, R.6    Nezu, J.7    Mayatepek, E.8
  • 26
    • 0034049311 scopus 로고    scopus 로고
    • A missense mutation in the OCTN2 gene associated with residual carnitine transport activity
    • 10.1002/(SICI)1098-1004(200003)15:3<238::AID-HUMU4>3.0.CO;2-3. 10679939
    • A missense mutation in the OCTN2 gene associated with residual carnitine transport activity. Y Wang MA Kelly TM Cowan N Longo, Hum Mutat 2000 15 238 245 10.1002/(SICI)1098-1004(200003)15:3<238::AID-HUMU4>3.0.CO;2-3 10679939
    • (2000) Hum Mutat , vol.15 , pp. 238-245
    • Wang, Y.1    Kelly, M.A.2    Cowan, T.M.3    Longo, N.4
  • 27
    • 0028850504 scopus 로고
    • Primary and secondary carnitine deficiency syndromes
    • 8576570
    • Primary and secondary carnitine deficiency syndromes. R Pons DC De Vivo, J Child Neurol 1995 10 Suppl 2 8 24 8576570
    • (1995) J Child Neurol , vol.10 , Issue.SUPPL 2 , pp. 198-24
    • Pons, R.1    De Vivo, D.C.2
  • 28
    • 0032746479 scopus 로고    scopus 로고
    • Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency
    • 10.1093/hmg/8.12.2247. 10545605
    • Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency. A Koizumi J Nozaki T Ohura T Kayo Y Wada J Nezu R Ohashi I Tamai Y Shoji G Takada S Kibira T Matsuishi A Tsuji, Hum Mol Genet 1999 8 2247 2254 10.1093/hmg/8.12.2247 10545605
    • (1999) Hum Mol Genet , vol.8 , pp. 2247-2254
    • Koizumi, A.1    Nozaki, J.2    Ohura, T.3    Kayo, T.4    Wada, Y.5    Nezu, J.6    Ohashi, R.7    Tamai, I.8    Shoji, Y.9    Takada, G.10    Kibira, S.11    Matsuishi, T.12    Tsuji, A.13
  • 30
    • 34548831939 scopus 로고    scopus 로고
    • A case of early diagnosed carnitine deficiency presenting with respiratory symptoms
    • 10.1159/000107675. 17726310
    • A case of early diagnosed carnitine deficiency presenting with respiratory symptoms. M Erguven O Yilmaz S Koc S Caki Y Ayhan M Donmez G Dolunay, Ann Nutr Metab 2007 51 331 334 10.1159/000107675 17726310
    • (2007) Ann Nutr Metab , vol.51 , pp. 331-334
    • Erguven, M.1    Yilmaz, O.2    Koc, S.3    Caki, S.4    Ayhan, Y.5    Donmez, M.6    Dolunay, G.7
  • 31
    • 0005419068 scopus 로고    scopus 로고
    • Two novel missense mutations of the OCTN2 gene (W283R and V446F) in a patient with primary systemic carnitine deficiency
    • 10.1002/(SICI)1098-1004(200001)15:1<118::AID-HUMU28>3.0.CO;2-8. 10612840
    • Two novel missense mutations of the OCTN2 gene (W283R and V446F) in a patient with primary systemic carnitine deficiency. E Mayatepek J Nezu I Tamai A Oku M Katsura M Shimane A Tsuji, Hum Mutat 2000 15 118 10.1002/(SICI)1098- 1004(200001)15:1<118::AID-HUMU28>3.0.CO;2-8 10612840
    • (2000) Hum Mutat , vol.15 , pp. 118
    • Mayatepek, E.1    Nezu, J.2    Tamai, I.3    Oku, A.4    Katsura, M.5    Shimane, M.6    Tsuji, A.7
  • 32
    • 0033585084 scopus 로고    scopus 로고
    • Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function
    • 10.1074/jbc.274.47.33388. 10559218
    • Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function. P Seth X Wu W Huang FH Leibach V Ganapathy, J Biol Chem 1999 274 33388 33392 10.1074/jbc.274.47.33388 10559218
    • (1999) J Biol Chem , vol.274 , pp. 33388-33392
    • Seth, P.1    Wu, X.2    Huang, W.3    Leibach, F.H.4    Ganapathy, V.5
  • 33
    • 0032997735 scopus 로고    scopus 로고
    • Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency
    • 10.1093/hmg/8.4.655. 10072434
    • Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency. NL Tang V Ganapathy X Wu J Hui P Seth PM Yuen RJ Wanders TF Fok NM Hjelm, Hum Mol Genet 1999 8 655 660 10.1093/hmg/8.4.655 10072434
    • (1999) Hum Mol Genet , vol.8 , pp. 655-660
    • Tang, N.L.1    Ganapathy, V.2    Wu, X.3    Hui, J.4    Seth, P.5    Yuen, P.M.6    Wanders, R.J.7    Fok, T.F.8    Hjelm, N.M.9
  • 34
    • 0242497007 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase II deficiency: A clinical, biochemical, and molecular review
    • 10.1097/01.LAB.0000098428.51765.83. 14615409
    • Carnitine palmitoyltransferase II deficiency: a clinical, biochemical, and molecular review. E Sigauke D Rakheja K Kitson MJ Bennett, Lab Invest 2003 83 1543 1554 10.1097/01.LAB.0000098428.51765.83 14615409
    • (2003) Lab Invest , vol.83 , pp. 1543-1554
    • Sigauke, E.1    Rakheja, D.2    Kitson, K.3    Bennett, M.J.4
  • 35
    • 28544444993 scopus 로고    scopus 로고
    • Current status of genetics research in inflammatory bowel disease
    • 16107869
    • Current status of genetics research in inflammatory bowel disease. S Vermeire P Rutgeerts, Genes Immun 2005 6 637 645 16107869
    • (2005) Genes Immun , vol.6 , pp. 637-645
    • Vermeire, S.1    Rutgeerts, P.2
  • 36
    • 0036197207 scopus 로고    scopus 로고
    • Fatty acid oxidation disorders
    • 10.1146/annurev.physiol.64.082201.154705. 11826276
    • Fatty acid oxidation disorders. P Rinaldo D Matern MJ Bennett, Annu Rev Physiol 2002 64 477 502 10.1146/annurev.physiol.64.082201.154705 11826276
    • (2002) Annu Rev Physiol , vol.64 , pp. 477-502
    • Rinaldo, P.1    Matern, D.2    Bennett, M.J.3
  • 37
    • 0031751184 scopus 로고    scopus 로고
    • Clinical and biochemical features of fatty acid oxidation disorders
    • 10.1097/00008480-199810060-00014. 9848022
    • Clinical and biochemical features of fatty acid oxidation disorders. P Rinaldo K Raymond A al-Odaib MJ Bennett, Curr Opin Pediatr 1998 10 615 621 10.1097/00008480-199810060-00014 9848022
    • (1998) Curr Opin Pediatr , vol.10 , pp. 615-621
    • Rinaldo, P.1    Raymond, K.2    Al-Odaib, A.3    Bennett, M.J.4
  • 38
    • 0032951920 scopus 로고    scopus 로고
    • Primary and secondary alterations of neonatal carnitine metabolism
    • 10.1016/S0146-0005(99)80047-0. 10331466
    • Primary and secondary alterations of neonatal carnitine metabolism. F Scaglia N Longo, Semin Perinatol 1999 23 152 161 10.1016/S0146-0005(99)80047-0 10331466
    • (1999) Semin Perinatol , vol.23 , pp. 152-161
    • Scaglia, F.1    Longo, N.2
  • 39
    • 0038042472 scopus 로고    scopus 로고
    • Treatment of carnitine deficiency
    • 10.1023/A:1024433100257. 12889658
    • Treatment of carnitine deficiency. SC Winter, J Inherit Metab Dis 2003 26 171 180 10.1023/A:1024433100257 12889658
    • (2003) J Inherit Metab Dis , vol.26 , pp. 171-180
    • Winter, S.C.1
  • 40
    • 0020546217 scopus 로고
    • Carnitine metabolism and deficiency syndromes
    • 6348429
    • Carnitine metabolism and deficiency syndromes. CJ Rebouche AG Engel, Mayo Clin Proc 1983 58 533 540 6348429
    • (1983) Mayo Clin Proc , vol.58 , pp. 533-540
    • Rebouche, C.J.1    Engel, A.G.2
  • 41
    • 0001812009 scopus 로고    scopus 로고
    • Carnitine deficiency: Primary and secondary syndromes
    • Austin, TX: R.G. Landes Company De Simone CFG
    • Carnitine deficiency: Primary and secondary syndromes. G Famularo F Matricardi E Nucera G Santini C De Simone, Carnitine Today Austin, TX: R.G. Landes Company, De Simone CFG, 1997 119 161
    • (1997) Carnitine Today , pp. 119-161
    • Famularo, G.1    Matricardi, F.2    Nucera, E.3    Santini, G.4    De Simone, C.5
  • 44
    • 33646079885 scopus 로고    scopus 로고
    • Effect of L-carnitine on the serum lipoproteins and HDL-C subclasses in hemodialysis patients
    • 10.1159/000087411. 16103722
    • Effect of L-carnitine on the serum lipoproteins and HDL-C subclasses in hemodialysis patients. H Argani M Rahbaninoubar A Ghorbanihagjo Z Golmohammadi N Rashtchizadeh, Nephron Clin Pract 2005 101 174 179 10.1159/000087411 16103722
    • (2005) Nephron Clin Pract , vol.101 , pp. 3174-179
    • Argani, H.1    Rahbaninoubar, M.2    Ghorbanihagjo, A.3    Golmohammadi, Z.4    Rashtchizadeh, N.5
  • 45
    • 0029954776 scopus 로고    scopus 로고
    • Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase i
    • 8679700
    • Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I. N Yamazaki Y Shinohara A Shima Y Yamanaka H Terada, Biochim Biophys Acta 1996 1307 157 161 8679700
    • (1996) Biochim Biophys Acta , vol.1307 , pp. 157-161
    • Yamazaki, N.1    Shinohara, Y.2    Shima, A.3    Yamanaka, Y.4    Terada, H.5
  • 46
    • 0030798104 scopus 로고    scopus 로고
    • Structural features of the gene encoding human muscle type carnitine palmitoyltransferase i
    • 10.1016/S0014-5793(97)00561-9. 9224698
    • Structural features of the gene encoding human muscle type carnitine palmitoyltransferase I. N Yamazaki Y Yamanaka Y Hashimoto Y Shinohara A Shima H Terada, FEBS Lett 1997 409 401 406 10.1016/S0014-5793(97)00561-9 9224698
    • (1997) FEBS Lett , vol.409 , pp. 401-406
    • Yamazaki, N.1    Yamanaka, Y.2    Hashimoto, Y.3    Shinohara, Y.4    Shima, A.5    Terada, H.6
  • 47
    • 38649109155 scopus 로고    scopus 로고
    • Substitutions of three amino acids in human heart/muscle type carnitine palmitoyltransferase i caused by single nucleotide polymorphisms
    • 10.1007/s10528-007-9129-3. 17987377
    • Substitutions of three amino acids in human heart/muscle type carnitine palmitoyltransferase I caused by single nucleotide polymorphisms. N Yamazaki T Matsuo M Kurata M Suzuki T Fujiwaki S Yamaguchi H Terada Y Shinohara, Biochem Genet 2008 46 54 63 10.1007/s10528-007-9129-3 17987377
    • (2008) Biochem Genet , vol.46 , pp. 54-63
    • Yamazaki, N.1    Matsuo, T.2    Kurata, M.3    Suzuki, M.4    Fujiwaki, T.5    Yamaguchi, S.6    Terada, H.7    Shinohara, Y.8
  • 48
    • 12144249792 scopus 로고    scopus 로고
    • Muscle carnitine palmitoyltransferase II deficiency: Clinical and molecular genetic features and diagnostic aspects
    • 10.1001/archneur.62.1.37. 15642848
    • Muscle carnitine palmitoyltransferase II deficiency: clinical and molecular genetic features and diagnostic aspects. M Deschauer T Wieser S Zierz, Arch Neurol 2005 62 37 41 10.1001/archneur.62.1.37 15642848
    • (2005) Arch Neurol , vol.62 , pp. 37-41
    • Deschauer, M.1    Wieser, T.2    Zierz, S.3
  • 49
    • 44949121542 scopus 로고    scopus 로고
    • Autopsy case of the neonatal form of carnitine palmitoyltransferase-II deficiency triggered by a novel disease-causing mutation del1737C
    • 10.1111/j.1440-1827.2008.02250.x. 18577113
    • Autopsy case of the neonatal form of carnitine palmitoyltransferase-II deficiency triggered by a novel disease-causing mutation del1737C. S Semba H Yasujima T Takano H Yokozaki, Pathol Int 2008 58 436 441 10.1111/j.1440-1827. 2008.02250.x 18577113
    • (2008) Pathol Int , vol.58 , pp. 436-441
    • Semba, S.1    Yasujima, H.2    Takano, T.3    Yokozaki, H.4
  • 52
    • 0023202923 scopus 로고
    • Carnitine metabolism in patients with chronic renal failure: Effect of L-carnitine supplementation
    • 3480977
    • Carnitine metabolism in patients with chronic renal failure: effect of L-carnitine supplementation. C Wanner S Forstner-Wanner C Rossle P Furst P Schollmeyer WH Horl, Kidney Int Suppl 1987 22 132 135 3480977
    • (1987) Kidney Int Suppl , vol.22 , pp. 19132-135
    • Wanner, C.1    Forstner-Wanner, S.2    Rossle, C.3    Furst, P.4    Schollmeyer, P.5    Horl, W.H.6
  • 53
    • 0023771024 scopus 로고
    • Carnitine abnormalities in patients with renal insufficiency. Pathophysiological and therapeutical aspects
    • 10.1159/000185137. 3065666
    • Carnitine abnormalities in patients with renal insufficiency. Pathophysiological and therapeutical aspects. C Wanner WH Horl, Nephron 1988 50 89 102 10.1159/000185137 3065666
    • (1988) Nephron , vol.50 , pp. 89-102
    • Wanner, C.1    Horl, W.H.2
  • 55
    • 29244472834 scopus 로고    scopus 로고
    • Debate forum: Carnitine supplements have not been demonstrated as effective in patients on long-term dialysis therapy
    • 10.1159/000089450. 16361854
    • Debate forum: carnitine supplements have not been demonstrated as effective in patients on long-term dialysis therapy. GJ Handelman, Blood Purif 2006 24 140 142 10.1159/000089450 16361854
    • (2006) Blood Purif , vol.24 , pp. 140-142
    • Handelman, G.J.1
  • 57
    • 33644900486 scopus 로고    scopus 로고
    • Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity
    • 10.1016/j.biopha.2005.06.014. 16472963
    • Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity. N Origlia M Migliori V Panichi C Filippi A Bertelli A Carpi L Giovannini, Biomed Pharmacother 2006 60 77 81 10.1016/j.biopha.2005.06. 014 16472963
    • (2006) Biomed Pharmacother , vol.60 , pp. 77-81
    • Origlia, N.1    Migliori, M.2    Panichi, V.3    Filippi, C.4    Bertelli, A.5    Carpi, A.6    Giovannini, L.7
  • 58
    • 50249164192 scopus 로고    scopus 로고
    • Is oral L: Acyl-carnitine an effective therapy for hepatic encephalopathy? Review of the literature
    • 18270833
    • Is Oral L: -Acyl-Carnitine an Effective Therapy for Hepatic Encephalopathy? Review of the Literature. NJ Shores EB Keeffe, Dig Dis Sci 2008 18270833
    • (2008) Dig Dis Sci
    • Shores, N.J.1    Keeffe, E.B.2
  • 60
    • 0031050889 scopus 로고    scopus 로고
    • Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat
    • 10.1002/hep.510250310. 9049197
    • Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat. G Therrien C Rose J Butterworth RF Butterworth, Hepatology 1997 25 551 556 10.1002/hep.510250310 9049197
    • (1997) Hepatology , vol.25 , pp. 551-556
    • Therrien, G.1    Rose, C.2    Butterworth, J.3    Butterworth, R.F.4
  • 62
    • 0035989796 scopus 로고    scopus 로고
    • L-carnitine administration reverses acute mental status changes in a chronic hemodialysis patient with hepatitis C infection
    • 12036203
    • L-carnitine administration reverses acute mental status changes in a chronic hemodialysis patient with hepatitis C infection. WJ DaVanzo ME Ullian, Clin Nephrol 2002 57 402 405 12036203
    • (2002) Clin Nephrol , vol.57 , pp. 402-405
    • Davanzo, W.J.1    Ullian, M.E.2
  • 64
    • 33846989018 scopus 로고    scopus 로고
    • Effects of L-acetylcarnitine on cirrhotic patients with hepatic coma: Randomized double-blind, placebo-controlled trial
    • 10.1007/s10620-006-9187-0. 17080254
    • Effects of L-acetylcarnitine on cirrhotic patients with hepatic coma: randomized double-blind, placebo-controlled trial. M Malaguarnera G Pistone M Astuto I Vecchio R Raffaele E Lo Giudice L Rampello, Dig Dis Sci 2006 51 2242 2247 10.1007/s10620-006-9187-0 17080254
    • (2006) Dig Dis Sci , vol.51 , pp. 2242-2247
    • Malaguarnera, M.1    Pistone, G.2    Astuto, M.3    Vecchio, I.4    Raffaele, R.5    Lo Giudice, E.6    Rampello, L.7
  • 66
    • 0028542935 scopus 로고
    • Pathogenetic mechanisms of acute hepatic encephalopathy
    • 7804799
    • Pathogenetic mechanisms of acute hepatic encephalopathy. KD Mullen R Gacad, New Horiz 1994 2 505 511 7804799
    • (1994) New Horiz , vol.2 , pp. 505-511
    • Mullen, K.D.1    Gacad, R.2
  • 67
    • 0033653231 scopus 로고    scopus 로고
    • Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: Relevance for its mode of action in Alzheimer's disease and geriatric depression
    • 10.1038/sj.mp.4000805. 11126392
    • Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. JW Pettegrew J Levine RJ McClure, Mol Psychiatry 2000 5 616 632 10.1038/sj.mp.4000805 11126392
    • (2000) Mol Psychiatry , vol.5 , pp. 616-632
    • Pettegrew, J.W.1    Levine, J.2    McClure, R.J.3
  • 68
    • 0017412248 scopus 로고
    • Deficiency of carnitine in cachectic cirrhotic patients
    • 10.1172/JCI108824. 893675
    • Deficiency of carnitine in cachectic cirrhotic patients. D Rudman CW Sewell JD Ansley, J Clin Invest 1977 60 716 723 10.1172/JCI108824 893675
    • (1977) J Clin Invest , vol.60 , pp. 716-723
    • Rudman, D.1    Sewell, C.W.2    Ansley, J.D.3
  • 69
    • 0014066191 scopus 로고
    • Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet
    • 6021815
    • Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet. LM DeCarli CS Lieber, J Nutr 1967 91 331 336 6021815
    • (1967) J Nutr , vol.91 , pp. 331-336
    • Decarli, L.M.1    Lieber, C.S.2
  • 70
    • 0000662450 scopus 로고
    • Alcohol and its relation to liver damage
    • 14456652
    • Alcohol and its relation to liver damage. G Klatskin, Gastroenterology 1961 41 443 451 14456652
    • (1961) Gastroenterology , vol.41 , pp. 443-451
    • Klatskin, G.1
  • 71
    • 0021275948 scopus 로고
    • Ameliorating effects of carnitine and its precursors on alcohol-induced fatty liver
    • 6424429
    • Ameliorating effects of carnitine and its precursors on alcohol-induced fatty liver. DS Sachan TH Rhew RA Ruark, Am J Clin Nutr 1984 39 738 744 6424429
    • (1984) Am J Clin Nutr , vol.39 , pp. 738-744
    • Sachan, D.S.1    Rhew, T.H.2    Ruark, R.A.3
  • 72
    • 0023033189 scopus 로고
    • Dose-dependent lipotropic effect of carnitine in chronic alcoholic rats
    • 3794832
    • Dose-dependent lipotropic effect of carnitine in chronic alcoholic rats. TH Rhew DS Sachan, J Nutr 1986 116 2263 2269 3794832
    • (1986) J Nutr , vol.116 , pp. 2263-2269
    • Rhew, T.H.1    Sachan, D.S.2
  • 73
    • 0014377596 scopus 로고
    • Inhibitory effects of alcohol on intestinal amino acid transport in vivo and in vitro
    • 5699991
    • Inhibitory effects of alcohol on intestinal amino acid transport in vivo and in vitro. Y Israel I Salazar E Rosenmann, J Nutr 1968 96 499 504 5699991
    • (1968) J Nutr , vol.96 , pp. 499-504
    • Israel, Y.1    Salazar, I.2    Rosenmann, E.3
  • 74
    • 34147129533 scopus 로고    scopus 로고
    • Modulation of carnitine palmitoyltransferase-1 for the treatment of obesity
    • 17458181
    • Modulation of carnitine palmitoyltransferase-1 for the treatment of obesity. FP Kuhajda GV Ronnett, Curr Opin Investig Drugs 2007 8 312 317 17458181
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 312-317
    • Kuhajda, F.P.1    Ronnett, G.V.2
  • 76
    • 0038037734 scopus 로고    scopus 로고
    • Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
    • 10.1038/nm873. 12754501
    • Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. S Obici Z Feng A Arduini R Conti L Rossetti, Nat Med 2003 9 756 761 10.1038/nm873 12754501
    • (2003) Nat Med , vol.9 , pp. 756-761
    • Obici, S.1    Feng, Z.2    Arduini, A.3    Conti, R.4    Rossetti, L.5
  • 77
    • 33645531123 scopus 로고    scopus 로고
    • Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
    • 10.1172/JCI26640. 16528412
    • Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. A Pocai TK Lam S Obici R Gutierrez-Juarez ED Muse A Arduini L Rossetti, J Clin Invest 2006 116 1081 1091 10.1172/JCI26640 16528412
    • (2006) J Clin Invest , vol.116 , pp. 1081-1091
    • Pocai, A.1    Lam, T.K.2    Obici, S.3    Gutierrez-Juarez, R.4    Muse, E.D.5    Arduini, A.6    Rossetti, L.7
  • 78
    • 31544465941 scopus 로고    scopus 로고
    • Molecular disruption of hypothalamic nutrient sensing induces obesity
    • 10.1038/nn1626. 16415870
    • Molecular disruption of hypothalamic nutrient sensing induces obesity. W He TK Lam S Obici L Rossetti, Nat Neurosci 2006 9 227 233 10.1038/nn1626 16415870
    • (2006) Nat Neurosci , vol.9 , pp. 227-233
    • He, W.1    Lam, T.K.2    Obici, S.3    Rossetti, L.4
  • 80
    • 0036065628 scopus 로고    scopus 로고
    • Central administration of oleic acid inhibits glucose production and food intake
    • 10.2337/diabetes.51.2.271. 11812732
    • Central administration of oleic acid inhibits glucose production and food intake. S Obici Z Feng K Morgan D Stein G Karkanias L Rossetti, Diabetes 2002 51 271 275 10.2337/diabetes.51.2.271 11812732
    • (2002) Diabetes , vol.51 , pp. 271-275
    • Obici, S.1    Feng, Z.2    Morgan, K.3    Stein, D.4    Karkanias, G.5    Rossetti, L.6
  • 82
    • 0016420661 scopus 로고
    • Glutaric aciduria; A "new" disorder of amino acid metabolism
    • 10.1016/0006-2944(75)90091-5. 1137568
    • Glutaric aciduria; a "new" disorder of amino acid metabolism. SI Goodman SP Markey PG Moe BS Miles CC Teng, Biochem Med 1975 12 12 21 10.1016/0006-2944(75)90091-5 1137568
    • (1975) Biochem Med , vol.12 , pp. 12-21
    • Goodman, S.I.1    Markey, S.P.2    Moe, P.G.3    Miles, B.S.4    Teng, C.C.5
  • 83
    • 0347319252 scopus 로고    scopus 로고
    • Pathomechanisms of neurodegeneration in glutaryl-CoA dehydrogenase deficiency
    • DOI 10.1002/ana.10784
    • Pathomechanisms of neurodegeneration in glutaryl-CoA dehydrogenase deficiency. S Kolker DM Koeller JG Okun GF Hoffmann, Ann Neurol 2004 55 7 12 10.1002/ana.10784 14705106 (Pubitemid 38067355)
    • (2004) Annals of Neurology , vol.55 , Issue.1 , pp. 7-12
    • Kolker, S.1    Koeller, D.M.2    Okun, J.G.3    Hoffmann, G.F.4
  • 85
    • 0034120821 scopus 로고    scopus 로고
    • Prevention of cerebral palsy in glutaric aciduria type 1 by dietary management
    • 10.1136/adc.82.1.67. 10630918
    • Prevention of cerebral palsy in glutaric aciduria type 1 by dietary management. AA Monavari ER Naughten, Arch Dis Child 2000 82 67 70 10.1136/adc.82.1.67 10630918
    • (2000) Arch Dis Child , vol.82 , pp. 67-70
    • Monavari, A.A.1    Naughten, E.R.2
  • 87
    • 0028055032 scopus 로고
    • Nutrition support for glutaric acidemia type i
    • 10.1016/0002-8223(94)90245-3. 8300996
    • Nutrition support for glutaric acidemia type I. S Yannicelli F Rohr ML Warman, J Am Diet Assoc 1994 94 183 188 10.1016/0002-8223(94)90245-3 8300996
    • (1994) J Am Diet Assoc , vol.94 , pp. 183-188
    • Yannicelli, S.1    Rohr, F.2    Warman, M.L.3
  • 88
    • 0017362682 scopus 로고
    • Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: Augmentation by thyroid hormone
    • 10.1016/0026-0495(77)90101-9. 846404
    • Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: augmentation by thyroid hormone. M Maebashi N Kawamura M Sato A Imamura K Yoshinaga, Metabolism 1977 26 351 356 10.1016/0026-0495(77)90101-9 846404
    • (1977) Metabolism , vol.26 , pp. 351-356
    • Maebashi, M.1    Kawamura, N.2    Sato, M.3    Imamura, A.4    Yoshinaga, K.5
  • 89
    • 35348863733 scopus 로고    scopus 로고
    • Acetyl-L-carnitine in diabetic polyneuropathy: Experimental and clinical data
    • discussion 45-16. 10.2165/00023210-200721001-00003. 17696589
    • Acetyl-L-carnitine in diabetic polyneuropathy: experimental and clinical data. AA Sima, CNS Drugs 2007 21 Suppl 1 13 23 discussion 45-16 10.2165/00023210-200721001-00003 17696589
    • (2007) CNS Drugs , vol.21 , Issue.SUPPL 1 , pp. 13-23
    • Sima, A.A.1
  • 90
    • 0021835873 scopus 로고
    • Effect of endocrine pancreas allotransplantation on diabetic nerve dysfunction
    • 10.1016/0026-0495(85)90021-6. 3927109
    • Effect of endocrine pancreas allotransplantation on diabetic nerve dysfunction. WJ Tze AA Sima J Tai, Metabolism 1985 34 721 725 10.1016/0026-0495(85)90021-6 3927109
    • (1985) Metabolism , vol.34 , pp. 721-725
    • Tze, W.J.1    Sima, A.A.2    Tai, J.3
  • 91
    • 0015241798 scopus 로고
    • Improvement in nerve conduction following treatment in newly diagnosed diabetics
    • 10.1016/S0140-6736(71)92415-9. 4100402
    • Improvement in nerve conduction following treatment in newly diagnosed diabetics. JD Ward CG Barnes DJ Fisher JD Jessop RW Baker, Lancet 1971 1 428 430 10.1016/S0140-6736(71)92415-9 4100402
    • (1971) Lancet , vol.1 , pp. 428-430
    • Ward, J.D.1    Barnes, C.G.2    Fisher, D.J.3    Jessop, J.D.4    Baker, R.W.5
  • 92
    • 0141740235 scopus 로고    scopus 로고
    • C-peptide and diabetic neuropathy
    • 10.1517/13543784.12.9.1471. 12943492
    • C-peptide and diabetic neuropathy. AA Sima, Expert Opin Investig Drugs 2003 12 1471 1488 10.1517/13543784.12.9.1471 12943492
    • (2003) Expert Opin Investig Drugs , vol.12 , pp. 1471-1488
    • Sima, A.A.1
  • 93
    • 0023748415 scopus 로고
    • Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil
    • 3136331
    • Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil. AA Sima V Bril V Nathaniel TA McEwen MB Brown SA Lattimer DA Greene, N Engl J Med 1988 319 548 555 3136331
    • (1988) N Engl J Med , vol.319 , pp. 548-555
    • Sima, A.A.1    Bril, V.2    Nathaniel, V.3    McEwen, T.A.4    Brown, M.B.5    Lattimer, S.A.6    Greene, D.A.7
  • 94
    • 0343144797 scopus 로고    scopus 로고
    • Metabolic response to injury and sepsis: Changes in protein metabolism
    • 10.1016/S0899-9007(97)00206-2. 9290110
    • Metabolic response to injury and sepsis: changes in protein metabolism. G Biolo G Toigo B Ciocchi R Situlin F Iscra A Gullo G Guarnieri, Nutrition 1997 13 52S 57S 10.1016/S0899-9007(97)00206-2 9290110
    • (1997) Nutrition , vol.13
    • Biolo, G.1    Toigo, G.2    Ciocchi, B.3    Situlin, R.4    Iscra, F.5    Gullo, A.6    Guarnieri, G.7
  • 95
    • 10644296222 scopus 로고    scopus 로고
    • Carnitine and its congeners: A metabolic pathway to the regulation of immune response and inflammation
    • 10.1196/annals.1320.012. 15591010
    • Carnitine and its congeners: a metabolic pathway to the regulation of immune response and inflammation. G Famularo C De Simone V Trinchieri L Mosca, Ann N Y Acad Sci 2004 1033 132 138 10.1196/annals.1320.012 15591010
    • (2004) Ann N y Acad Sci , vol.1033 , pp. 132-138
    • Famularo, G.1    De Simone, C.2    Trinchieri, V.3    Mosca, L.4
  • 96
    • 0028904231 scopus 로고
    • A new era for carnitine?
    • 10.1016/0167-5699(95)80159-6. 7779248
    • A new era for carnitine? G Famularo C De Simone, Immunol Today 1995 16 211 213 10.1016/0167-5699(95)80159-6 7779248
    • (1995) Immunol Today , vol.16 , pp. 211-213
    • Famularo, G.1    De Simone, C.2
  • 97
    • 0032199201 scopus 로고    scopus 로고
    • Carnitine deprivation adversely affects cardiovascular response to bacterial endotoxin (LPS) in the anesthetized neonatal pig
    • 10.1097/00024382-199811000-00012. 9840655
    • Carnitine deprivation adversely affects cardiovascular response to bacterial endotoxin (LPS) in the anesthetized neonatal pig. D Penn L Zhang PJ Bobrowski M Quinn X Liu KH McDonough, Shock 1998 10 377 382 10.1097/00024382- 199811000-00012 9840655
    • (1998) Shock , vol.10 , pp. 377-382
    • Penn, D.1    Zhang, L.2    Bobrowski, P.J.3    Quinn, M.4    Liu, X.5    McDonough, K.H.6
  • 98
    • 0033073865 scopus 로고    scopus 로고
    • Carnitine deprivation adversely affects cardiac performance in the lipopolysaccharide- and hypoxia/reoxygenation-stressed piglet heart
    • 10.1097/00024382-199902000-00009. 10030799
    • Carnitine deprivation adversely affects cardiac performance in the lipopolysaccharide- and hypoxia/reoxygenation-stressed piglet heart. D Penn L Zhang PJ Bobrowski M Quinn KH McDonough, Shock 1999 11 120 126 10.1097/00024382-199902000-00009 10030799
    • (1999) Shock , vol.11 , pp. 120-126
    • Penn, D.1    Zhang, L.2    Bobrowski, P.J.3    Quinn, M.4    McDonough, K.H.5
  • 99
    • 0035083570 scopus 로고    scopus 로고
    • Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function
    • 10.1046/j.1432-1327.2001.02012.x. 11231295
    • Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. S Trumbeckaite JR Opalka C Neuhof S Zierz FN Gellerich, Eur J Biochem 2001 268 1422 1429 10.1046/j.1432-1327.2001.02012.x 11231295
    • (2001) Eur J Biochem , vol.268 , pp. 1422-1429
    • Trumbeckaite, S.1    Opalka, J.R.2    Neuhof, C.3    Zierz, S.4    Gellerich, F.N.5
  • 100
    • 0346788905 scopus 로고    scopus 로고
    • Myocardial carnitine palmitoyltransferase i as a target for oxidative modification in inflammation and sepsis
    • 10.1042/BST0311133. 14641011
    • Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis. S Eaton K Fukumoto G Stefanutti L Spitz VA Zammit A Pierro, Biochem Soc Trans 2003 31 1133 1136 10.1042/BST0311133 14641011
    • (2003) Biochem Soc Trans , vol.31 , pp. 1133-1136
    • Eaton, S.1    Fukumoto, K.2    Stefanutti, G.3    Spitz, L.4    Zammit, V.A.5    Pierro, A.6
  • 102
    • 0019816616 scopus 로고
    • Urinary excretion of carnitne in burned patients
    • 10.1016/0305-4179(81)90030-9
    • Urinary excretion of carnitne in burned patients. G Cederblad J Larsson H Nordstrom B Schildt, Burns 1981 8 102 109 10.1016/0305-4179(81)90030-9
    • (1981) Burns , vol.8 , pp. 102-109
    • Cederblad, G.1    Larsson, J.2    Nordstrom, H.3    Schildt, B.4
  • 103
    • 0021733959 scopus 로고
    • Rationales for micronutrient supplementation in diabetes
    • 10.1016/0306-9877(84)90025-2. 6325854
    • Rationales for micronutrient supplementation in diabetes. MF McCarty EJ Rubin, Med Hypotheses 1984 13 139 151 10.1016/0306-9877(84)90025-2 6325854
    • (1984) Med Hypotheses , vol.13 , pp. 139-151
    • McCarty, M.F.1    Rubin, E.J.2
  • 104
    • 21344436376 scopus 로고    scopus 로고
    • The additive effects of carnitine and ascorbic acid on distally burned dorsal skin flap in rats
    • 15917712
    • The additive effects of carnitine and ascorbic acid on distally burned dorsal skin flap in rats. E Arslan Y Basterzi A Aksoy C Majka S Unal A Sari F Demirkan, Med Sci Monit 2005 11 R176 180 15917712
    • (2005) Med Sci Monit , vol.11
    • Arslan, E.1    Basterzi, Y.2    Aksoy, A.3    Majka, C.4    Unal, S.5    Sari, A.6    Demirkan, F.7
  • 105
    • 17444385966 scopus 로고    scopus 로고
    • The Effect of L-Carnitine on Wound Healing by Secondary Intention in an Animal Model
    • The Effect of L-Carnitine on Wound Healing by Secondary Intention in an Animal Model. S Koybasi Y Taner, Wounds 2005 17 62 66
    • (2005) Wounds , vol.17 , pp. 62-66
    • Koybasi, S.1    Taner, Y.2
  • 106
    • 0017337523 scopus 로고
    • Plasma carnitine levels in children with protein-calorie malnutrition before and after rehabilitation
    • 10.1016/0009-8981(77)90513-7. 403033
    • Plasma carnitine levels in children with protein-calorie malnutrition before and after rehabilitation. L Khan MS Bamji, Clin Chim Acta 1977 75 163 166 10.1016/0009-8981(77)90513-7 403033
    • (1977) Clin Chim Acta , vol.75 , pp. 163-166
    • Khan, L.1    Bamji, M.S.2
  • 107
    • 0018396343 scopus 로고
    • Tissue carnitine deficiency due to dietary lysine dificiency: Triglyceride accumulation and concomitant impairment in fatty acid oxidation
    • 430211
    • Tissue carnitine deficiency due to dietary lysine dificiency: triglyceride accumulation and concomitant impairment in fatty acid oxidation. L Khan MS Bamji, J Nutr 1979 109 24 31 430211
    • (1979) J Nutr , vol.109 , pp. 24-31
    • Khan, L.1    Bamji, M.S.2
  • 108
    • 0032722489 scopus 로고    scopus 로고
    • Plasma and urine carnitine levels and carnitine supplementation in children with malnutrition
    • 10.1093/tropej/45.5.294. 10584472
    • Plasma and urine carnitine levels and carnitine supplementation in children with malnutrition. H Alp Z Orbak F Akcay H Tan H Aksoy, J Trop Pediatr 1999 45 294 296 10.1093/tropej/45.5.294 10584472
    • (1999) J Trop Pediatr , vol.45 , pp. 294-296
    • Alp, H.1    Orbak, Z.2    Akcay, F.3    Tan, H.4    Aksoy, H.5
  • 109
    • 0026513892 scopus 로고
    • Prevalence of carnitine depletion in critically ill patients with undernutrition
    • 10.1016/0026-0495(92)90146-2. 1736038
    • Prevalence of carnitine depletion in critically ill patients with undernutrition. A Wennberg A Hyltander A Sjoberg B Arfvidsson R Sandstrom I Wickstrom K Lundholm, Metabolism 1992 41 165 171 10.1016/0026-0495(92)90146-2 1736038
    • (1992) Metabolism , vol.41 , pp. 165-171
    • Wennberg, A.1    Hyltander, A.2    Sjoberg, A.3    Arfvidsson, B.4    Sandstrom, R.5    Wickstrom, I.6    Lundholm, K.7
  • 111
    • 33749648743 scopus 로고    scopus 로고
    • PPARalpha agonists up-regulate organic cation transporters in rat liver cells
    • 10.1016/j.bbrc.2006.09.099. 17011512
    • PPARalpha agonists up-regulate organic cation transporters in rat liver cells. S Luci S Geissler B Konig A Koch GI Stangl F Hirche K Eder, Biochem Biophys Res Commun 2006 350 704 708 10.1016/j.bbrc.2006.09.099 17011512
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 704-708
    • Luci, S.1    Geissler, S.2    Konig, B.3    Koch, A.4    Stangl, G.I.5    Hirche, F.6    Eder, K.7
  • 112
    • 35148877188 scopus 로고    scopus 로고
    • Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats
    • 10.1017/S000711450775691X. 17524183
    • Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats. A Koch B Konig S Luci GI Stangl K Eder, Br J Nutr 2007 98 882 889 10.1017/S000711450775691X 17524183
    • (2007) Br J Nutr , vol.98 , pp. 882-889
    • Koch, A.1    Konig, B.2    Luci, S.3    Stangl, G.I.4    Eder, K.5
  • 114
    • 58149146893 scopus 로고    scopus 로고
    • In the rat brain acetyl-L: carnitine treatment modulates the expression of genes involved in neuronal ceroid lipofuscinosis
    • 18726077
    • In the Rat Brain Acetyl-L: -carnitine Treatment Modulates the Expression of Genes Involved in Neuronal Ceroid Lipofuscinosis. G Traina R Bernardi E Cataldo M Macchi M Durante M Brunelli, Mol Neurobiol 2008 18726077
    • (2008) Mol Neurobiol
    • Traina, G.1    Bernardi, R.2    Cataldo, E.3    MacChi, M.4    Durante, M.5    Brunelli, M.6
  • 115
    • 25844517550 scopus 로고    scopus 로고
    • Correlations between genotype, ultrastructural morphology and clinical phenotype in the neuronal ceroid lipofuscinoses
    • 10.1007/s10048-005-0218-3. 15965709
    • Correlations between genotype, ultrastructural morphology and clinical phenotype in the neuronal ceroid lipofuscinoses. SE Mole RE Williams HH Goebel, Neurogenetics 2005 6 107 126 10.1007/s10048-005-0218-3 15965709
    • (2005) Neurogenetics , vol.6 , pp. 107-126
    • Mole, S.E.1    Williams, R.E.2    Goebel, H.H.3
  • 116
    • 0033613189 scopus 로고    scopus 로고
    • Phenotypic reversal of the btn1 defects in yeast by chloroquine: A yeast model for Batten disease
    • 10.1073/pnas.96.20.11341. 10500178
    • Phenotypic reversal of the btn1 defects in yeast by chloroquine: a yeast model for Batten disease. DA Pearce CJ Carr B Das F Sherman, Proc Natl Acad Sci USA 1999 96 11341 11345 10.1073/pnas.96.20.11341 10500178
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11341-11345
    • Pearce, D.A.1    Carr, C.J.2    Das, B.3    Sherman, F.4
  • 117
    • 33749067148 scopus 로고    scopus 로고
    • The effect of acetyl-L-carnitine administration on persons with Down syndrome
    • 10.1016/j.ridd.2004.07.009. 16621446
    • The effect of acetyl-L-carnitine administration on persons with Down syndrome. SM Pueschel, Res Dev Disabil 2006 27 599 604 10.1016/j.ridd.2004.07. 009 16621446
    • (2006) Res Dev Disabil , vol.27 , pp. 599-604
    • Pueschel, S.M.1
  • 119
    • 33747286388 scopus 로고    scopus 로고
    • Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets
    • 10.1016/j.ejphar.2006.06.025. 16904103
    • Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. C Ramassamy, Eur J Pharmacol 2006 545 51 64 10.1016/j.ejphar.2006.06.025 16904103
    • (2006) Eur J Pharmacol , vol.545 , pp. 51-64
    • Ramassamy, C.1
  • 120
    • 46349088952 scopus 로고    scopus 로고
    • Diseases caused by defects of mitochondrial carriers: A review
    • 10.1016/j.bbabio.2008.03.008. 18406340
    • Diseases caused by defects of mitochondrial carriers: a review. F Palmieri, Biochim Biophys Acta 2008 1777 564 578 10.1016/j.bbabio.2008.03.008 18406340
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 564-578
    • Palmieri, F.1
  • 122
    • 47349124572 scopus 로고    scopus 로고
    • Carnitine worsens both injury and recovery of contractile function after transient ischemia in perfused rat heart
    • 10.1007/BF03168229. 18663990
    • Carnitine worsens both injury and recovery of contractile function after transient ischemia in perfused rat heart. R Diaz J Lorita M Soley I Ramirez, J Physiol Biochem 2008 64 1 8 10.1007/BF03168229 18663990
    • (2008) J Physiol Biochem , vol.64 , pp. 1-8
    • Diaz, R.1    Lorita, J.2    Soley, M.3    Ramirez, I.4
  • 123
    • 0031443202 scopus 로고    scopus 로고
    • Carnitine and its derivatives in cardiovascular disease
    • 10.1016/S0033-0620(97)80037-0. 9406679
    • Carnitine and its derivatives in cardiovascular disease. MA Arsenian, Prog Cardiovasc Dis 1997 40 265 286 10.1016/S0033-0620(97)80037-0 9406679
    • (1997) Prog Cardiovasc Dis , vol.40 , pp. 265-286
    • Arsenian, M.A.1
  • 124
    • 10644296223 scopus 로고    scopus 로고
    • Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: A review
    • 10.1196/annals.1320.007. 15591005
    • Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review. R Ferrari E Merli G Cicchitelli D Mele A Fucili C Ceconi, Ann N Y Acad Sci 2004 1033 79 91 10.1196/annals.1320.007 15591005
    • (2004) Ann N y Acad Sci , vol.1033 , pp. 79-91
    • Ferrari, R.1    Merli, E.2    Cicchitelli, G.3    Mele, D.4    Fucili, A.5    Ceconi, C.6
  • 125
    • 0029101882 scopus 로고
    • Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: The L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial
    • 10.1016/0735-1097(95)80010-E. 7608438
    • Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. S Iliceto D Scrutinio P Bruzzi G D'Ambrosio L Boni M Di Biase G Biasco PG Hugenholtz P Rizzon, J Am Coll Cardiol 1995 26 380 387 10.1016/0735-1097(95)80010-E 7608438
    • (1995) J Am Coll Cardiol , vol.26 , pp. 380-387
    • Iliceto, S.1    Scrutinio, D.2    Bruzzi, P.3    D'Ambrosio, G.4    Boni, L.5    Di Biase, M.6    Biasco, G.7    Hugenholtz, P.G.8    Rizzon, P.9
  • 126
    • 0033981684 scopus 로고    scopus 로고
    • Myocardial infarction and left ventricular remodeling: Results of the CEDIM trial. Carnitine Ecocardiografia Digitalizzata Infarto Miocardico
    • 10.1067/mhj.2000.103918. 10650326
    • Myocardial infarction and left ventricular remodeling: results of the CEDIM trial. Carnitine Ecocardiografia Digitalizzata Infarto Miocardico. P Colonna S Iliceto, Am Heart J 2000 139 124 130 10.1067/mhj.2000.103918 10650326
    • (2000) Am Heart J , vol.139 , pp. 19124-130
    • Colonna, P.1    Iliceto, S.2
  • 127
    • 33751098827 scopus 로고    scopus 로고
    • Metabolic treatment with L-carnitine in acute anterior ST segment elevation myocardial infarction. A randomized controlled trial
    • 10.1159/000093131. 16685128
    • Metabolic treatment with L-carnitine in acute anterior ST segment elevation myocardial infarction. A randomized controlled trial. G Tarantini D Scrutinio P Bruzzi L Boni P Rizzon S Iliceto, Cardiology 2006 106 215 223 10.1159/000093131 16685128
    • (2006) Cardiology , vol.106 , pp. 215-223
    • Tarantini, G.1    Scrutinio, D.2    Bruzzi, P.3    Boni, L.4    Rizzon, P.5    Iliceto, S.6
  • 128
    • 0030063942 scopus 로고    scopus 로고
    • A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction
    • 10.1136/pgmj.72.843.45. 8746285
    • A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. RB Singh MA Niaz P Agarwal R Beegum SS Rastogi DS Sachan, Postgrad Med J 1996 72 45 50 10.1136/pgmj.72.843.45 8746285
    • (1996) Postgrad Med J , vol.72 , pp. 45-50
    • Singh, R.B.1    Niaz, M.A.2    Agarwal, P.3    Beegum, R.4    Rastogi, S.S.5    Sachan, D.S.6
  • 129
    • 36849033861 scopus 로고    scopus 로고
    • L-carnitine as an adjunct therapy to percutaneous coronary intervention for non-ST elevation myocardial infarction
    • 10.1007/s10557-007-6056-9. 17955358
    • L-carnitine as an adjunct therapy to percutaneous coronary intervention for non-ST elevation myocardial infarction. YZ Xue LX Wang HZ Liu XW Qi XH Wang HZ Ren, Cardiovasc Drugs Ther 2007 21 445 448 10.1007/s10557-007-6056-9 17955358
    • (2007) Cardiovasc Drugs Ther , vol.21 , pp. 445-448
    • Xue, Y.Z.1    Wang, L.X.2    Liu, H.Z.3    Qi, X.W.4    Wang, X.H.5    Ren, H.Z.6
  • 130
    • 85047697283 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and neuromuscular disease
    • 10.1002/1097-4598(200102)24:2<170::AID-MUS30>3.0.CO;2-0. 11180201
    • Mitochondrial dysfunction and neuromuscular disease. RA Nardin DR Johns, Muscle Nerve 2001 24 170 191 10.1002/1097-4598(200102)24:2<170::AID- MUS30>3.0.CO;2-0 11180201
    • (2001) Muscle Nerve , vol.24 , pp. 170-191
    • Nardin, R.A.1    Johns, D.R.2
  • 131
    • 0017657534 scopus 로고
    • Muscle carnitine levels in neuromuscular disease
    • 10.1016/0022-510X(77)90075-2. 925714
    • Muscle carnitine levels in neuromuscular disease. PR Borum HP Broquist RJ Roelops, J Neurol Sci 1977 34 279 286 10.1016/0022-510X(77)90075-2 925714
    • (1977) J Neurol Sci , vol.34 , pp. 279-286
    • Borum, P.R.1    Broquist, H.P.2    Roelops, R.J.3
  • 132
    • 0015800677 scopus 로고
    • Muscle carnitine palmityltransferase deficiency and myoglobinuria
    • 10.1126/science.182.4115.929. 4745596
    • Muscle carnitine palmityltransferase deficiency and myoglobinuria. S DiMauro PM DiMauro, Science 1973 182 929 931 10.1126/science.182.4115.929 4745596
    • (1973) Science , vol.182 , pp. 929-931
    • Dimauro, S.1    Dimauro, P.M.2
  • 133
    • 27144539588 scopus 로고    scopus 로고
    • Science review: Carnitine in the treatment of valproic acid-induced toxicity - What is the evidence?
    • 10.1186/cc3742. 16277730
    • Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence? PE Lheureux A Penaloza S Zahir M Gris, Crit Care 2005 9 431 440 10.1186/cc3742 16277730
    • (2005) Crit Care , vol.9 , pp. 431-440
    • Lheureux, P.E.1    Penaloza, A.2    Zahir, S.3    Gris, M.4
  • 134
    • 0021915865 scopus 로고
    • Valproic acid associated abnormalities of carnitine metabolism
    • 10.1016/S0140-6736(85)91481-3. 2858698
    • Valproic acid associated abnormalities of carnitine metabolism. JV Murphy KM Marquardt AL Shug, Lancet 1985 1 820 821 10.1016/S0140-6736(85)91481-3 2858698
    • (1985) Lancet , vol.1 , pp. 820-821
    • Murphy, J.V.1    Marquardt, K.M.2    Shug, A.L.3
  • 137
    • 85045292494 scopus 로고    scopus 로고
    • Effect of L-carnitine treatment for valproate-induced hepatotoxicity
    • 11839873
    • Effect of L-carnitine treatment for valproate-induced hepatotoxicity. DC DeVivo, Neurology 2002 58 507 508 11839873
    • (2002) Neurology , vol.58 , pp. 507-508
    • Devivo, D.C.1
  • 139
    • 0027522968 scopus 로고
    • Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity
    • 10.1111/j.1528-1157.1993.tb02419.x. 8453944
    • Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity. H Siemes H Nau K Schultze W Wittfoht E Drews J Penzien U Seidel, Epilepsia 1993 34 332 346 10.1111/j.1528-1157.1993.tb02419.x 8453944
    • (1993) Epilepsia , vol.34 , pp. 332-346
    • Siemes, H.1    Nau, H.2    Schultze, K.3    Wittfoht, W.4    Drews, E.5    Penzien, J.6    Seidel, U.7
  • 140
    • 32644477036 scopus 로고    scopus 로고
    • Propionyl-L-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model
    • 10.1016/j.phrs.2005.12.005. 16436331
    • Propionyl-L-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model. AA Al-Majed MM Sayed-Ahmed AA Al-Yahya AM Aleisa SS Al-Rejaie OA Al-Shabanah, Pharmacol Res 2006 53 278 286 10.1016/j.phrs.2005.12.005 16436331
    • (2006) Pharmacol Res , vol.53 , pp. 278-286
    • Al-Majed, A.A.1    Sayed-Ahmed, M.M.2    Al-Yahya, A.A.3    Aleisa, A.M.4    Al-Rejaie, S.S.5    Al-Shabanah, O.A.6
  • 142
    • 0024337077 scopus 로고
    • Age-dependent decrease of carnitine content in muscle of mice and humans
    • 10.1016/0006-291X(89)91360-0. 2742580
    • Age-dependent decrease of carnitine content in muscle of mice and humans. M Costell JE O'Connor S Grisolia, Biochem Biophys Res Commun 1989 161 1135 1143 10.1016/0006-291X(89)91360-0 2742580
    • (1989) Biochem Biophys Res Commun , vol.161 , pp. 1135-1143
    • Costell, M.1    O'Connor, J.E.2    Grisolia, S.3
  • 144
    • 0037133283 scopus 로고    scopus 로고
    • Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid
    • 10.1073/pnas.261709299. 11854529
    • Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. J Liu E Head AM Gharib W Yuan RT Ingersoll TM Hagen CW Cotman BN Ames, Proc Natl Acad Sci USA 2002 99 2356 2361 10.1073/pnas.261709299 11854529
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2356-2361
    • Liu, J.1    Head, E.2    Gharib, A.M.3    Yuan, W.4    Ingersoll, R.T.5    Hagen, T.M.6    Cotman, C.W.7    Ames, B.N.8
  • 145
    • 0037133304 scopus 로고    scopus 로고
    • Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
    • 10.1073/pnas.261708898. 11854487
    • Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. TM Hagen J Liu J Lykkesfeldt CM Wehr RT Ingersoll V Vinarsky JC Bartholomew BN Ames, Proc Natl Acad Sci USA 2002 99 1870 1875 10.1073/pnas.261708898 11854487
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1870-1875
    • Hagen, T.M.1    Liu, J.2    Lykkesfeldt, J.3    Wehr, C.M.4    Ingersoll, R.T.5    Vinarsky, V.6    Bartholomew, J.C.7    Ames, B.N.8
  • 146
    • 0032441653 scopus 로고    scopus 로고
    • HMG CoA reductase inhibitor accelerates aging effect on diaphragm mitochondrial respiratory function in rats
    • 9861446
    • HMG CoA reductase inhibitor accelerates aging effect on diaphragm mitochondrial respiratory function in rats. S Sugiyama, Biochem Mol Biol Int 1998 46 923 931 9861446
    • (1998) Biochem Mol Biol Int , vol.46 , pp. 923-931
    • Sugiyama, S.1
  • 147
    • 33746628488 scopus 로고    scopus 로고
    • L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle
    • 16870625
    • L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle. S Sethumadhavan P Chinnakannu, J Gerontol A Biol Sci Med Sci 2006 61 650 659 16870625
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , pp. 650-659
    • Sethumadhavan, S.1    Chinnakannu, P.2
  • 148
    • 11244351578 scopus 로고    scopus 로고
    • Supplementation of L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats
    • 10.1080/03610730590882846. 15842073
    • Supplementation of L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats. S Kumaran M Subathra M Balu C Panneerselvam, Exp Aging Res 2005 31 55 67 10.1080/03610730590882846 15842073
    • (2005) Exp Aging Res , vol.31 , pp. 55-67
    • Kumaran, S.1    Subathra, M.2    Balu, M.3    Panneerselvam, C.4
  • 149
    • 29244465892 scopus 로고    scopus 로고
    • Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: Role of carnitine and lipoic acid
    • 10.1007/s11010-005-8234-z. 16311908
    • Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid. S Kumaran KS Panneerselvam S Shila K Sivarajan C Panneerselvam, Mol Cell Biochem 2005 280 83 89 10.1007/s11010-005-8234-z 16311908
    • (2005) Mol Cell Biochem , vol.280 , pp. 83-89
    • Kumaran, S.1    Panneerselvam, K.S.2    Shila, S.3    Sivarajan, K.4    Panneerselvam, C.5
  • 151
    • 0025240059 scopus 로고
    • Levels of carnitines in brain and other tissues of rats of different ages: Effect of acetyl-L-carnitine administration
    • 10.1016/0531-5565(90)90043-2. 2369927
    • Levels of carnitines in brain and other tissues of rats of different ages: effect of acetyl-L-carnitine administration. F Maccari A Arseni P Chiodi MT Ramacci L Angelucci, Exp Gerontol 1990 25 127 134 10.1016/0531-5565(90)90043- 2 2369927
    • (1990) Exp Gerontol , vol.25 , pp. 127-134
    • MacCari, F.1    Arseni, A.2    Chiodi, P.3    Ramacci, M.T.4    Angelucci, L.5
  • 153
    • 0023656894 scopus 로고
    • Fatty acid oxidation in bone tissue and bone cells in culture. Characterization and hormonal influences
    • 3325035
    • Fatty acid oxidation in bone tissue and bone cells in culture. Characterization and hormonal influences. G Adamek R Felix HL Guenther H Fleisch, Biochem J 1987 248 129 137 3325035
    • (1987) Biochem J , vol.248 , pp. 129-137
    • Adamek, G.1    Felix, R.2    Guenther, H.L.3    Fleisch, H.4
  • 154
    • 46049088291 scopus 로고    scopus 로고
    • Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats
    • 10.1016/j.phymed.2008.02.026. 18539446
    • Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. S Hooshmand A Balakrishnan RM Clark KQ Owen SI Koo BH Arjmandi, Phytomedicine 2008 15 595 601 10.1016/j.phymed.2008.02.026 18539446
    • (2008) Phytomedicine , vol.15 , pp. 595-601
    • Hooshmand, S.1    Balakrishnan, A.2    Clark, R.M.3    Owen, K.Q.4    Koo, S.I.5    Arjmandi, B.H.6
  • 155
    • 48249119206 scopus 로고    scopus 로고
    • Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells
    • 10.1097/ICO.0b013e318165b19e. 18520508
    • Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells. RM Corrales L Luo EY Chang SC Pflugfelder, Cornea 2008 27 574 579 10.1097/ICO.0b013e318165b19e 18520508
    • (2008) Cornea , vol.27 , pp. 574-579
    • Corrales, R.M.1    Luo, L.2    Chang, E.Y.3    Pflugfelder, S.C.4
  • 157
    • 0036143134 scopus 로고    scopus 로고
    • Impaired functional visual acuity of dry eye patients
    • DOI 10.1016/S0002-9394(01)01365-4, PII S0002939401013654
    • Impaired functional visual acuity of dry eye patients. E Goto Y Yagi Y Matsumoto K Tsubota, Am J Ophthalmol 2002 133 181 186 10.1016/S0002-9394(01) 01365-4 11812420 (Pubitemid 34072045)
    • (2002) American Journal of Ophthalmology , vol.133 , Issue.2 , pp. 181-186
    • Goto, E.1    Yagi, Y.2    Matsumoto, Y.3    Tsubota, K.4
  • 158
    • 0031984088 scopus 로고    scopus 로고
    • Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation
    • 10.1097/00003226-199801000-00007. 9436879
    • Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation. SC Pflugfelder SC Tseng O Sanabria H Kell CG Garcia C Felix W Feuer BL Reis, Cornea 1998 17 38 56 10.1097/00003226-199801000-00007 9436879
    • (1998) Cornea , vol.17 , pp. 38-56
    • Pflugfelder, S.C.1    Tseng, S.C.2    Sanabria, O.3    Kell, H.4    Garcia, C.G.5    Felix, C.6    Feuer, W.7    Reis, B.L.8
  • 160
    • 56149083695 scopus 로고    scopus 로고
    • Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium
    • 10.1167/iovs.07-1528. 18641280
    • Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium. Q Garrett S Xu PA Simmons J Vehige JL Flanagan MD Willcox, Invest Ophthalmol Vis Sci 2008 49 4844 4849 10.1167/iovs.07-1528 18641280
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4844-4849
    • Garrett, Q.1    Xu, S.2    Simmons, P.A.3    Vehige, J.4    Flanagan, J.L.5    Willcox, M.D.6
  • 161
    • 67650317884 scopus 로고    scopus 로고
    • L-carnitine and short chain ester in tears from patients with dry eye
    • 10.1097/OPX.0b013e318194e767. 19156017
    • L-carnitine and short chain ester in tears from patients with dry eye. N Pescosolido B Imperatrice A Koverech M Messano, Optom Vis Sci 2009 86 132 138 10.1097/OPX.0b013e318194e767 19156017
    • (2009) Optom Vis Sci , vol.86 , pp. 5132-138
    • Pescosolido, N.1    Imperatrice, B.2    Koverech, A.3    Messano, M.4
  • 162
    • 0028098188 scopus 로고
    • Human tear film electrolyte concentrations in health and dry-eye disease
    • 10.1097/00004397-199403410-00005. 8169071
    • Human tear film electrolyte concentrations in health and dry-eye disease. JP Gilbard, Int Ophthalmol Clin 1994 34 27 36 10.1097/00004397-199403410-00005 8169071
    • (1994) Int Ophthalmol Clin , vol.34 , pp. 27-36
    • Gilbard, J.P.1
  • 163
    • 0031080421 scopus 로고    scopus 로고
    • In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event
    • 10.1006/exer.1996.0188. 9176053
    • In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event. P Pessotto R Liberati O Petrella L Romanelli M Calvani G Peluso, Exp Eye Res 1997 64 195 201 10.1006/exer.1996.0188 9176053
    • (1997) Exp Eye Res , vol.64 , pp. 195-201
    • Pessotto, P.1    Liberati, R.2    Petrella, O.3    Romanelli, L.4    Calvani, M.5    Peluso, G.6
  • 164
    • 45549101505 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase i and Acyl-CoA dehydrogenase 9 in retina: Insights of retinopathy in mitochondrial trifunctional protein defects
    • 10.1167/iovs.07-1094. 18385088
    • Carnitine palmitoyltransferase I and Acyl-CoA dehydrogenase 9 in retina: insights of retinopathy in mitochondrial trifunctional protein defects. E Roomets T Kivela T Tyni, Invest Ophthalmol Vis Sci 2008 49 1660 1664 10.1167/iovs.07-1094 18385088
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1660-1664
    • Roomets, E.1    Kivela, T.2    Tyni, T.3
  • 165
    • 0031956979 scopus 로고    scopus 로고
    • Ophthalmologic findings in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation: A new type of hereditary metabolic chorioretinopathy
    • 10.1016/S0161-6420(98)95019-9. 9593380
    • Ophthalmologic findings in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation: a new type of hereditary metabolic chorioretinopathy. T Tyni T Kivela M Lappi P Summanen E Nikoskelainen H Pihko, Ophthalmology 1998 105 810 824 10.1016/S0161-6420(98)95019-9 9593380
    • (1998) Ophthalmology , vol.105 , pp. 810-824
    • Tyni, T.1    Kivela, T.2    Lappi, M.3    Summanen, P.4    Nikoskelainen, E.5    Pihko, H.6
  • 166
    • 0032957435 scopus 로고    scopus 로고
    • Dietary management of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD). A case report and survey
    • 10.1023/A:1005437616934. 10234607
    • Dietary management of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD). A case report and survey. M Gillingham S Van Calcar D Ney J Wolff C Harding, J Inherit Metab Dis 1999 22 123 131 10.1023/A:1005437616934 10234607
    • (1999) J Inherit Metab Dis , vol.22 , pp. 123-131
    • Gillingham, M.1    Van Calcar, S.2    Ney, D.3    Wolff, J.4    Harding, C.5
  • 167
    • 0031808147 scopus 로고    scopus 로고
    • Ophthalmic pathology in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation
    • 10.1080/02713689808951227. 9663844
    • Ophthalmic pathology in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation. T Tyni H Pihko T Kivela, Curr Eye Res 1998 17 551 559 10.1080/02713689808951227 9663844
    • (1998) Curr Eye Res , vol.17 , pp. 551-559
    • Tyni, T.1    Pihko, H.2    Kivela, T.3
  • 168
    • 10644250580 scopus 로고    scopus 로고
    • Carnitine deficiency disorders in children
    • 10.1196/annals.1320.004. 15591002
    • Carnitine deficiency disorders in children. CA Stanley, Ann N Y Acad Sci 2004 1033 42 51 10.1196/annals.1320.004 15591002
    • (2004) Ann N y Acad Sci , vol.1033 , pp. 42-51
    • Stanley, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.