Identification and characterization of a NA+-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids

Journal of Biological Chemistry

Volumn 275, Issue 13, 2000, Pages 9690-9698

  Fukasawa, Yoshiki ^a   Segawa, Hiroko ^a,b   Kim, Ju Young ^a   Chairoungdua, Arthit ^a   Kim, Do Kyung ^a   Matsuo, Hirotaka ^a,c   Cha, Seok Ho ^a   Endou, Hitoshi ^a   Kanai, Yoshikatsu ^a  

^a KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBUTYRIC ACID; AMINO ACID DERIVATIVE; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DISULFIDE BOND; ENZYME SPECIFICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; DNA, COMPLEMENTARY; HYDROGEN-ION CONCENTRATION; MICE; MOLECULAR SEQUENCE DATA; RATS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM; SUBSTRATE SPECIFICITY; XENOPUS;

ANIMALIA; MAMMALIA;

EID: 0034737775     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.13.9690     Document Type: Article

References (46)

1. Christensen, H. N. (1990) Physiol. Rev. 70, 43-77
2. Palacin, M., Estevez, R., Bertran, J., and Zorzano, A. (1998) Physiol. Rev. 78, 969-1054
3. Kanai, Y., Segawa, H., Miyamoto, K., Uchino, H., Takeda, E., and Endou, H. (1998) J. Biol. Chem. 273, 23629-23632
4. Mastroberardino, L., Spindler, B., Pfeiffer, R., Skelly, P. J., Loffing, J., Shoemaker, C. B., and Verrey, F. (1998) Nature 395, 288-291
5. Mannion, B. A., Kolesnikova, T. V., Lin, S.-H., Thompson, N. L., and Hemler, M. E. (1998) J. Biol. Chem. 273, 33127-33129
6. Nakamura, E., Sato, M., Yang, H., Miyagawa, F., Harasaki, M., Tomita, K., Matsuoka, S., Noma, A., Iwai, K., and Minato, N. (1999) J. Biol. Chem. 274, 3009-3016
7. Haynes, B. F., Hemler, M. E., Mann, D. L., Eisenbarth, G. S., Shelhamer, J., Mostowski, H. S.,Thomas, C. A., Strominger, J. L., and Fauci, A. S. (1981) J. Immunol. 126, 1409-1414
8. Hemler, M. E., and Strominger, J. L. (1982) J. Immunol. 129, 623-628
9. Yagita, H., Masuko, T., and Hashimoto, Y. (1986) Cancer Res. 46, 1478-1484
10. Fenczik, C. A., Sethi, T., Ramos, J. W., Hughes, P. E., and Ginsberg, M. H. (1997) Nature 390, 81-85
11. Quackenbush, E., Clabby, M., Gottesdiener, K. M., Barbosa, J., Jones, N. H., Strominger, J. L., Speck, S., and Leiden, J. M. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6526-6530
12. Pineda, M., Fernandez, E., Torrents, D., Estevez, R., Lopez, C., Camps, M., Lloberas, J., Zorzano, A., and Palacin, M. (1999) J. Biol. Chem. 274, 19738-19744
13. Segawa, H., Fukasawa, Y., Miyamoto, K., Takeda, E., Endou, H., and Kanai, Y. (1999) J. Biol. Chem. 274, 19745-19751
14. Torrents, D., Estevez, R., Pineda, M., Fernandez, E., Lloberas, J., Shi, Y.-B., Zorzano, A., and Palacin, M. (1998) J. Biol. Chem. 273, 32437-32445
15. Pfeiffer, R., Rossier, G., Spindler, B., Meier, C.,Kuhn, L., and Verrey, F. (1999) EMBO J. 18, 49-57
16. Sato, H., Tamba, M., Ishii, T.. and Bannai, S. (1999) J. Biol. Chem. 274, 11455-11458
17. Chairoungdua, A., Segawa, H., Kim, J. Y., Miyamoto, K, Haga, H., Fukui, Y., Mizoguchi, K., Ito, H., Takeda, E., Endou, H., and Kanai, Y. (1999) J. Biol. Chem. 274, 28845-28848
18. International Cystinuria Consortium (1999) Nat. Genet. 23, 52-57
19. Barker, G. A., and Ellory, J. C. (1990) Exp. Physiopl. 75, 3-26
20. Utsunomiya-Tate, N., Endou, H., and Kanai, Y. (1996) J. Biol. Chem. 271, 14883-14890
21. Utsunomiya-Tate, N., Endou, H., and Kanai, Y. (1997) FEBS Lett. 416, 312-316
22. Hirokawa, T., Boon-Chieng, S., and Mitaku, S. (1998) Bioinformatics 14, 378-379
23. Altman, A., Carderas, J. M., Houghteu, R. A., Dixon, F. J., Argyrios, N., and Theofilopoulos, A. N. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 2176-2180
24. Thorens, B., Sarkar, H. K., Kaback, H. R., and Lodish, H. F. (1988) Cell 55, 281-290
25. Kanai, Y., and Hediger, M. A. (1992) Nature 360, 467-471
26. Kanai, Y., Nussberger, S., Romero, M. F., Boron, W. F., Hebert, S. C and Hediger, M. A. (1995) J. Biol. Chem. 270, 16561-16568
27. Kanai, Y., Stelzner, M. G., Lee, W.-S., Wells, R. G., Brown, D., and Hediger, M. A. (1992) Am. J. Physiol. 263, F1087-F1092
28. Hara, H., and Ogawa, M. (1976) Am. J. Hematol. 1, 453-458
29. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayashi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, H., and Nomura, N. (1996) DNA Res. 3, 321-329
30. Isnard, A. D., Thomas, D., and Surdin-Kerjan, Y. (1996) J. Mol. Biol. 262, 473-483
31. Pfeiffer, R., Spindler, B., Loffing, J., Skelly, P. J., Shoemaker, C. B., and Verrey, F. (1998) FEBS Lett. 439, 157-162
32. Christensen, H. N., Handlogten, M. E., Lam, I., Tager, H. S., and Zand, R. (1969) J. Biol. Chem. 244, 1510-1520
33. Hashimoto, A., and Oka, T. (1997)Prog. Neurobiol. 52, 325-353
34. Sekine, T., Watanabe, N., Hosoyamada, M., Kanai, Y., and Endou, H. (1997) J. Biol. Chem. 272, 18526-18529
35. Zerangue, N., and Kavanaugh, M. P. (1996) J. Physiol. (Land.) 493, 419-423
36. Kavanaugh, M. P., Bendahan, A., Zerangue, N., Zhang, Y., and Kanner, B. I. (1997) J. Biol. Chem. 272, 1703-1708
37. Fincham, D. A., Mason, D. K., and Young, J. D. (1985) Biochem. J. 227, 13-20
38. Vadgama, J. V., and Christensen, H. N. (1985) J. Biol. Chem. 260, 2912-2921
39. Fincham, D. A., Wolowyk, M. W., and Young, J. D. (1990) J. Exp. Biol. 154, 355-370
40. Gallardo, M. A., and Sanchez, J. (1993) J. Membr. Biol. 134, 251-259
41. Norman, P. S. R., and Mann, G. E. (1987) J. Membr. Biol. 96, 153-163
42. Kuhlmann, M. K., and Vadgama, J. V. (1991) J. Biol. Chem. 266, 15042-15047
43. Young, J. D., Ellory, J. C., and Tucker, E. M. (1976) Biochem. J. 154, 43-48
44. Young, J. D., and Ellory, J. C. (1977) Biochem. J. 162, 33-38
45. Gallardo, M. A., Canals, M. A., Albi, J. L., and Sanchez, J. (1994) J. Membr. Biol. 140, 189-196
46. Apiwattanakul, N., Sekine, T., Chairoungdua, A., Kanai, Y., Nakajima, N., Sophasan, S., and Endou, H. (1999) Mol. Pharmacol. 55, 847-854