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Volumn 16, Issue , 2010, Pages 1823-1831

Transport of L-carnitine in human corneal and conjunctival epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; 2,4 DINITROPHENOL; CARNITINE; GAMMA BUTYROBETAINE; IODOACETIC ACID; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; SODIUM AZIDE; TETRYLAMMONIUM;

EID: 77956958965     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (28)

References (35)
  • 1
    • 0031080421 scopus 로고    scopus 로고
    • In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event
    • Pessotto P, Liberati R, Petrella O, Romanelli L, Calvani M, Peluso G. In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event. Exp Eye Res 1997; 64: 195-201.
    • (1997) Exp Eye Res , vol.64 , pp. 195-201
    • Pessotto, P.1    Liberati, R.2    Petrella, O.3    Romanelli, L.4    Calvani, M.5    Peluso, G.6
  • 2
    • 48249119206 scopus 로고    scopus 로고
    • Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells
    • Corrales RM, Luo L, Chang EY, Pflugfelder SC. Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells. Cornea 2008; 27: 574-579.
    • (2008) Cornea , vol.27 , pp. 574-579
    • Corrales, R.M.1    Luo, L.2    Chang, E.Y.3    Pflugfelder, S.C.4
  • 5
    • 0031868466 scopus 로고    scopus 로고
    • Genetic disorders of carnitine metabolism and their nutritional management
    • Kerner J, Hoppel C. Genetic disorders of carnitine metabolism and their nutritional management. Annu Rev Nutr 1998; 18: 179-206.
    • (1998) Annu Rev Nutr , vol.18 , pp. 179-206
    • Kerner, J.1    Hoppel, C.2
  • 6
    • 0034717940 scopus 로고    scopus 로고
    • Fatty acid import into mitochondria
    • Kerner J, Hoppel C. Fatty acid import into mitochondria. Biochim Biophys Acta 2000; 1486: 1-17.
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 1-17
    • Kerner, J.1    Hoppel, C.2
  • 9
    • 0034013856 scopus 로고    scopus 로고
    • Functional characterization of organic cation drug transport in the pigmented rabbit conjunctiva
    • Ueda H, Horibe Y, Kim KJ, Lee VH. Functional characterization of organic cation drug transport in the pigmented rabbit conjunctiva. Invest Ophthalmol Vis Sci 2000; 41: 870-876.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 870-876
    • Ueda, H.1    Horibe, Y.2    Kim, K.J.3    Lee, V.H.4
  • 10
    • 56149083695 scopus 로고    scopus 로고
    • Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium
    • Garrett Q, Xu S, Simmons PA, Vehige J, Flanagan JL, Willcox MD. Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium. Invest Ophthalmol Vis Sci 2008; 49: 4844-4849.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4844-4849
    • Garrett, Q.1    Xu, S.2    Simmons, P.A.3    Vehige, J.4    Flanagan, J.L.5    Willcox, M.D.6
  • 12
    • 1242295185 scopus 로고    scopus 로고
    • The SLC22 drug transporter family
    • Koepsell H, Endou H. The SLC22 drug transporter family. Pflugers Arch 2004; 447: 666-676.
    • (2004) Pflugers Arch , vol.447 , pp. 666-676
    • Koepsell, H.1    Endou, H.2
  • 15
    • 3242676117 scopus 로고    scopus 로고
    • L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2
    • Lahjouji K, Elimrani I, Lafond J, Leduc L, Qureshi IA, Mitchell GA. L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2. Am J Physiol Cell Physiol 2004; 287: C263-C269.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Lahjouji, K.1    Elimrani, I.2    Lafond, J.3    Leduc, L.4    Qureshi, I.A.5    Mitchell, G.A.6
  • 16
    • 0032935034 scopus 로고    scopus 로고
    • Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations
    • Yabuuchi H, Tamai I, Nezu J, Sakamoto K, Oku A, Shimane M, Sai Y, Tsuji A. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. J Pharmacol Exp Ther 1999; 289: 768-773.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 768-773
    • Yabuuchi, H.1    Tamai, I.2    Nezu, J.3    Sakamoto, K.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 17
    • 0034704135 scopus 로고    scopus 로고
    • Molecular and functional characterization of organic cation/carnitine transporter family in mice
    • Tamai I, Ohashi R, Nezu JI, Sai Y, Kobayashi D, Oku A, Shimane M, Tsuji A. Molecular and functional characterization of organic cation/carnitine transporter family in mice. J Biol Chem 2000; 275: 40064-40072.
    • (2000) J Biol Chem , vol.275 , pp. 40064-40072
    • Tamai, I.1    Ohashi, R.2    Nezu, J.I.3    Sai, Y.4    Kobayashi, D.5    Oku, A.6    Shimane, M.7    Tsuji, A.8
  • 18
    • 0031434178 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human pHdependent organic cation transporter, OCTN1
    • Tamai I, Yabuuchi H, Nezu J, Sai Y, Oku A, Shimane M, Tsuji A. Cloning and characterization of a novel human pHdependent organic cation transporter, OCTN1. FEBS Lett 1997; 419: 107-111.
    • (1997) FEBS Lett , vol.419 , pp. 107-111
    • Tamai, I.1    Yabuuchi, H.2    Nezu, J.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 20
    • 0032493741 scopus 로고    scopus 로고
    • Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
    • Tamai I, Ohashi R, Nezu J, Yabuuchi H, Oku A, Shimane M, Sai Y, Tsuji A. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J Biol Chem 1998; 273: 20378-20382.
    • (1998) J Biol Chem , vol.273 , pp. 20378-20382
    • Tamai, I.1    Ohashi, R.2    Nezu, J.3    Yabuuchi, H.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 22
    • 0035870096 scopus 로고    scopus 로고
    • Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes
    • Nakanishi T, Hatanaka T, Huang W, Prasad PD, Leibach FH, Ganapathy ME, Ganapathy V. Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes. J Physiol 2001; 532: 297-304.
    • (2001) J Physiol , vol.532 , pp. 297-304
    • Nakanishi, T.1    Hatanaka, T.2    Huang, W.3    Prasad, P.D.4    Leibach, F.H.5    Ganapathy, M.E.6    Ganapathy, V.7
  • 23
    • 34248366944 scopus 로고    scopus 로고
    • Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing
    • Garrett Q, Simmons PA, Xu S, Vehige J, Zhao Z, Ehrmann K, Willcox M. Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing. Invest Ophthalmol Vis Sci 2007; 48: 1559-1567.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 1559-1567
    • Garrett, Q.1    Simmons, P.A.2    Xu, S.3    Vehige, J.4    Zhao, Z.5    Ehrmann, K.6    Willcox, M.7
  • 27
    • 75749150209 scopus 로고    scopus 로고
    • Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier
    • Tachikawa M, Takeda Y, Tomi M, Hosoya K. Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier. Invest Ophthalmol Vis Sci 2010; 51: 430-436.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 430-436
    • Tachikawa, M.1    Takeda, Y.2    Tomi, M.3    Hosoya, K.4
  • 28
    • 0029030612 scopus 로고
    • Characterization of Lcarnitine transport by rat kidney brush-border-membrane vesicles
    • Stieger B, O'Neill B, Krahenbuhl S. Characterization of Lcarnitine transport by rat kidney brush-border-membrane vesicles. Biochem J 1995; 309: 643-647.
    • (1995) Biochem J , vol.309 , pp. 643-647
    • Stieger, B.1    O'Neill, B.2    Krahenbuhl, S.3
  • 29
    • 33746926424 scopus 로고    scopus 로고
    • Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid
    • Okamura N, Ohnishi S, Shimaoka H, Norikura R, Hasegawa H. Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. Pharm Res 2006; 23: 1729-1735.
    • (2006) Pharm Res , vol.23 , pp. 1729-1735
    • Okamura, N.1    Ohnishi, S.2    Shimaoka, H.3    Norikura, R.4    Hasegawa, H.5
  • 30
    • 56149095274 scopus 로고    scopus 로고
    • Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment
    • Ohnishi S, Okamura N, Sakamoto S, Hasegawa H, Norikura R, Kanaoka E, Takahashi K, Horie K, Sakamoto K, Baba T. Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment. Drug Metab Pharmacokinet 2008; 23: 293-303.
    • (2008) Drug Metab Pharmacokinet , vol.23 , pp. 293-303
    • Ohnishi, S.1    Okamura, N.2    Sakamoto, S.3    Hasegawa, H.4    Norikura, R.5    Kanaoka, E.6    Takahashi, K.7    Horie, K.8    Sakamoto, K.9    Baba, T.10
  • 31
    • 0032696186 scopus 로고    scopus 로고
    • Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
    • Ohashi R, Tamai I, Yabuuchi H, Nezu JI, Oku A, Sai Y, Shimane M, Tsuji A. Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J Pharmacol Exp Ther 1999; 291: 778-784.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 778-784
    • Ohashi, R.1    Tamai, I.2    Yabuuchi, H.3    Nezu, J.I.4    Oku, A.5    Sai, Y.6    Shimane, M.7    Tsuji, A.8
  • 32
    • 0032767691 scopus 로고    scopus 로고
    • Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter
    • Wu X, Huang W, Prasad PD, Seth P, Rajan DP, Leibach FH, Chen J, Conway SJ, Ganapathy V. Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. J Pharmacol Exp Ther 1999; 290: 1482-1492.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1482-1492
    • Wu, X.1    Huang, W.2    Prasad, P.D.3    Seth, P.4    Rajan, D.P.5    Leibach, F.H.6    Chen, J.7    Conway, S.J.8    Ganapathy, V.9
  • 33
    • 75749150209 scopus 로고    scopus 로고
    • Involvement of OCTN2 in the Transport of Acetyl-L-Carnitine across the Inner Blood-Retinal Barrier
    • Tachikawa M, Takeda Y, Tomi M, Hosoya K. Involvement of OCTN2 in the Transport of Acetyl-L-Carnitine across the Inner Blood-Retinal Barrier. Invest Ophthalmol Vis Sci 2010; 51: 430-436.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 430-436
    • Tachikawa, M.1    Takeda, Y.2    Tomi, M.3    Hosoya, K.4
  • 35
    • 0034212998 scopus 로고    scopus 로고
    • Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta
    • Wu X, George RL, Huang W, Wang H, Conway SJ, Leibach FH, Ganapathy V. Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta 2000; 1466: 315-327.
    • (2000) Biochim Biophys Acta , vol.1466 , pp. 315-327
    • Wu, X.1    George, R.L.2    Huang, W.3    Wang, H.4    Conway, S.J.5    Leibach, F.H.6    Ganapathy, V.7


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