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Volumn 10, Issue 8, 2010, Pages 617-624

Pharmacogenomics of human ABC transporter ABCC11 (MRP8): Potential risk of breast cancer and chemotherapy failure

Author keywords

Apocrine gland; Earwax; Estrogen receptor; Mastopathy; Multidrug resistance; Nucleoside; Single nucleotide polymorphism (SNP); Tamoxifen

Indexed keywords

ABC TRANSPORTER; CYCLOPHOSPHAMIDE; CYTARABINE; EPIRUBICIN; ESTRADIOL; FLUOROURACIL; FOLIC ACID; METHOTREXATE; PACLITAXEL; TAMOXIFEN;

EID: 79551646271     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152010794473975     Document Type: Review
Times cited : (33)

References (54)
  • 2
    • 57149130819 scopus 로고    scopus 로고
    • Drug therapy and personalized health care: Pharmacogenomics in perspective
    • Sadee, W. Drug therapy and personalized health care: pharmacogenomics in perspective. Pharm. Res. 2008, 25 (12), 2713-2719.
    • (2008) Pharm. Res. , vol.25 , Issue.12 , pp. 2713-2719
    • Sadee, W.1
  • 6
    • 77952895164 scopus 로고    scopus 로고
    • Drug transporter pharmacogenetics in nucleoside-based therapies
    • Errasti-Murugarren, E.; Pastor-Anglada, M. Drug transporter pharmacogenetics in nucleoside-based therapies. Pharmacogenomics 2010, 11 (6), 809-841.
    • (2010) Pharmacogenomics , vol.11 , Issue.6 , pp. 809-841
    • Errasti-Murugarren, E.1    Pastor-Anglada, M.2
  • 7
    • 50149108146 scopus 로고    scopus 로고
    • Pharmacogenomic importance of ABCG2
    • Cusatis, G.; Sparreboom, A. Pharmacogenomic importance of ABCG2. Pharmacogenomics 2008, 9 (8), 1005-1009.
    • (2008) Pharmacogenomics , vol.9 , Issue.8 , pp. 1005-1009
    • Cusatis, G.1    Sparreboom, A.2
  • 9
    • 0037131888 scopus 로고    scopus 로고
    • Pharmacogenetics of CYP enzymes and drug transporters: Remarkable recent advances
    • Kim, R. B. Pharmacogenetics of CYP enzymes and drug transporters: remarkable recent advances. Adv. Drug Deliv. Rev. 2002, 54 (10), 1241-1242.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , Issue.10 , pp. 1241-1242
    • Kim, R.B.1
  • 12
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst, P.; Elferink, R. O. Mammalian ABC transporters in health and disease. Annu. Rev. Biochem. 2002, 71, 537-592.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 15
    • 69349102208 scopus 로고    scopus 로고
    • A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene
    • Nakano, M.; Miwa, N.; Hirano, A.; Yoshiura, K.; Niikawa, N. A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene. BMC Genet. 2009, 10, 42.
    • (2009) BMC Genet. , vol.10 , pp. 42
    • Nakano, M.1    Miwa, N.2    Hirano, A.3    Yoshiura, K.4    Niikawa, N.5
  • 16
    • 76249119000 scopus 로고    scopus 로고
    • Genetic analysis of ABCG2 gene C421A polymorphism with gout disease in Chinese Han male population
    • Wang, B.; Miao, Z.; Liu, S.; Wang, J.; Zhou, S.; Han, L.; Meng, D.; Wang, Y.; Li, C.; Ma, X. Genetic analysis of ABCG2 gene C421A polymorphism with gout disease in Chinese Han male population. Hum. Genet. 2010, 127 (2), 245-246.
    • (2010) Hum. Genet. , vol.127 , Issue.2 , pp. 245-246
    • Wang, B.1    Miao, Z.2    Liu, S.3    Wang, J.4    Zhou, S.5    Han, L.6    Meng, D.7    Wang, Y.8    Li, C.9    Ma, X.10
  • 17
    • 67649886415 scopus 로고    scopus 로고
    • Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
    • Woodward, O. M.; Kottgen, A.; Coresh, J.; Boerwinkle, E.; Guggino, W. B.; Kottgen, M. Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout. Proc. Natl. Acad. Sci. USA, 2009, 106 (25), 10338-10342.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.25 , pp. 10338-10342
    • Woodward, O.M.1    Kottgen, A.2    Coresh, J.3    Boerwinkle, E.4    Guggino, W.B.5    Kottgen, M.6
  • 19
    • 0035834572 scopus 로고    scopus 로고
    • Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12
    • Yabuuchi, H.; Shimizu, H.; Takayanagi, S.; Ishikawa, T. Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12. Biochem. Biophys. Res. Commun. 2001, 288 (4), 933-939.
    • (2001) Biochem. Biophys. Res. Commun. , vol.288 , Issue.4 , pp. 933-939
    • Yabuuchi, H.1    Shimizu, H.2    Takayanagi, S.3    Ishikawa, T.4
  • 21
    • 2442451598 scopus 로고    scopus 로고
    • MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer
    • Bera, T. K.; Lee, S.; Salvatore, G.; Lee, B.; Pastan, I. MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer. Mol. Med. 2001, 7 (8), 509-516.
    • (2001) Mol. Med. , vol.7 , Issue.8 , pp. 509-516
    • Bera, T.K.1    Lee, S.2    Salvatore, G.3    Lee, B.4    Pastan, I.5
  • 22
    • 0038512144 scopus 로고    scopus 로고
    • Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12
    • Shimizu, H.; Taniguchi, H.; Hippo, Y.; Hayashizaki, Y.; Aburatani, H.; Ishikawa, T. Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12. Gene 2003, 310, 17-28.
    • (2003) Gene , vol.310 , pp. 17-28
    • Shimizu, H.1    Taniguchi, H.2    Hippo, Y.3    Hayashizaki, Y.4    Aburatani, H.5    Ishikawa, T.6
  • 23
    • 31144475523 scopus 로고    scopus 로고
    • Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system
    • Bortfeld, M.; Rius, M.; Konig, J.; Herold-Mende, C.; Nies, A. T.; Keppler, D. Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system. Neuroscience 2006, 137 (4), 1247-1257.
    • (2006) Neuroscience , vol.137 , Issue.4 , pp. 1247-1257
    • Bortfeld, M.1    Rius, M.2    Konig, J.3    Herold-Mende, C.4    Nies, A.T.5    Keppler, D.6
  • 24
    • 13444260049 scopus 로고    scopus 로고
    • Transport of bile acids, sulfated steroids, estradiol 17-beta-Dglucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)
    • Chen, Z. S.; Guo, Y.; Belinsky, M. G.; Kotova, E.; Kruh, G. D. Transport of bile acids, sulfated steroids, estradiol 17-beta-Dglucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11). Mol. Pharmacol. 2005, 67 (2), 545-557.
    • (2005) Mol. Pharmacol. , vol.67 , Issue.2 , pp. 545-557
    • Chen, Z.S.1    Guo, Y.2    Belinsky, M.G.3    Kotova, E.4    Kruh, G.D.5
  • 25
    • 3142757047 scopus 로고    scopus 로고
    • Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma
    • Bieche, I.; Girault, I.; Urbain, E.; Tozlu, S.; Lidereau, R. Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma. Breast Cancer Res. 2004, 6 (3), R252-263.
    • (2004) Breast Cancer Res. , vol.6 , Issue.3
    • Bieche, I.1    Girault, I.2    Urbain, E.3    Tozlu, S.4    Lidereau, R.5
  • 26
    • 33746742363 scopus 로고    scopus 로고
    • Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients
    • Park, S.; Shimizu, C.; Shimoyama, T.; Takeda, M.; Ando, M.; Kohno, T.; Katsumata, N.; Kang, Y. K.; Nishio, K.; Fujiwara, Y. Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients. Breast Cancer Res. Treat. 2006, 99 (1), 9-17.
    • (2006) Breast Cancer Res. Treat. , vol.99 , Issue.1 , pp. 9-17
    • Park, S.1    Shimizu, C.2    Shimoyama, T.3    Takeda, M.4    Ando, M.5    Kohno, T.6    Katsumata, N.7    Kang, Y.K.8    Nishio, K.9    Fujiwara, Y.10
  • 27
    • 41349092741 scopus 로고    scopus 로고
    • ABCC11 expression is regulated by estrogen in MCF7 cells, correlated with estrogen receptor alpha expression in postmenopausal breast tumors and overexpressed in tamoxifenresistant breast cancer cells
    • Honorat, M.; Mesnier, A.; Vendrell, J.; Guitton, J.; Bieche, I.; Lidereau, R.; Kruh, G. D.; Dumontet, C.; Cohen, P.; Payen, L. ABCC11 expression is regulated by estrogen in MCF7 cells, correlated with estrogen receptor alpha expression in postmenopausal breast tumors and overexpressed in tamoxifenresistant breast cancer cells. Endocr. Relat. Cancer 2008, 15 (1), 125-138.
    • (2008) Endocr. Relat. Cancer , vol.15 , Issue.1 , pp. 125-138
    • Honorat, M.1    Mesnier, A.2    Vendrell, J.3    Guitton, J.4    Bieche, I.5    Lidereau, R.6    Kruh, G.D.7    Dumontet, C.8    Cohen, P.9    Payen, L.10
  • 28
    • 66649104180 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes
    • Hauswald, S.; Duque-Afonso, J.; Wagner, M. M.; Schertl, F. M.; Lubbert, M.; Peschel, C.; Keller, U.; Licht, T. Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. Clin. Cancer Res. 2009, 15 (11), 3705-3715.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.11 , pp. 3705-3715
    • Hauswald, S.1    Duque-Afonso, J.2    Wagner, M.M.3    Schertl, F.M.4    Lubbert, M.5    Peschel, C.6    Keller, U.7    Licht, T.8
  • 29
    • 3943059566 scopus 로고    scopus 로고
    • Roles of N-linked glycans in the endoplasmic reticulum
    • Helenius, A.; Aebi, M. Roles of N-linked glycans in the endoplasmic reticulum. Annu. Rev. Biochem. 2004, 73, 1019-1049.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 1019-1049
    • Helenius, A.1    Aebi, M.2
  • 30
    • 0033521072 scopus 로고    scopus 로고
    • Setting the standards: Quality control in the secretory pathway
    • Ellgaard, L.; Molinari, M.; Helenius, A. Setting the standards: quality control in the secretory pathway. Science 1999, 286 (5446), 1882-1888.
    • (1999) Science , vol.286 , Issue.5446 , pp. 1882-1888
    • Ellgaard, L.1    Molinari, M.2    Helenius, A.3
  • 31
    • 3142587059 scopus 로고    scopus 로고
    • Protein folding and quality control in the endoplasmic reticulum
    • Kleizen, B.; Braakman, I. Protein folding and quality control in the endoplasmic reticulum. Curr. Opin. Cell Biol. 2004, 16 (4), 343-349.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , Issue.4 , pp. 343-349
    • Kleizen, B.1    Braakman, I.2
  • 32
    • 0036702298 scopus 로고    scopus 로고
    • ER-associated degradation in protein quality control and cellular regulation
    • Hampton, R. Y. ER-associated degradation in protein quality control and cellular regulation. Curr. Opin. Cell Biol. 2002, 14 (4), 476-482.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , Issue.4 , pp. 476-482
    • Hampton, R.Y.1
  • 33
    • 0035424237 scopus 로고    scopus 로고
    • ER quality control: Towards an understanding at the molecular level
    • Ellgaard, L.; Helenius, A. ER quality control: towards an understanding at the molecular level. Curr. Opin. Cell Biol. 2001, 13 (4), 431-437.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , Issue.4 , pp. 431-437
    • Ellgaard, L.1    Helenius, A.2
  • 34
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori, K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 2000, 101 (5), 451-454.
    • (2000) Cell , vol.101 , Issue.5 , pp. 451-454
    • Mori, K.1
  • 36
    • 34347363131 scopus 로고    scopus 로고
    • Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1)
    • Sakurai, A.; Onishi, Y.; Hirano, H.; Seigneuret, M.; Obanayama, K.; Kim, G.; Liew, E. L.; Sakaeda, T.; Yoshiura, K.; Niikawa, N.; Sakurai, M.; Ishikawa, T. Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1). Biochemistry 2007, 46 (26), 7678-7693.
    • (2007) Biochemistry , vol.46 , Issue.26 , pp. 7678-7693
    • Sakurai, A.1    Onishi, Y.2    Hirano, H.3    Seigneuret, M.4    Obanayama, K.5    Kim, G.6    Liew, E.L.7    Sakaeda, T.8    Yoshiura, K.9    Niikawa, N.10    Sakurai, M.11    Ishikawa, T.12
  • 37
    • 0023897325 scopus 로고
    • Morphological differences between secretory cells of wet and dry types of human ceruminous glands
    • Shugyo, Y.; Sudo, N.; Kanai, K.; Yamashita, T.; Kumazawa, T.; Kanamura, S. Morphological differences between secretory cells of wet and dry types of human ceruminous glands. Am. J. Anat. 1988, 181 (4), 377-384.
    • (1988) Am. J. Anat. , vol.181 , Issue.4 , pp. 377-384
    • Shugyo, Y.1    Sudo, N.2    Kanai, K.3    Yamashita, T.4    Kumazawa, T.5    Kanamura, S.6
  • 38
    • 33747378330 scopus 로고    scopus 로고
    • Endoscopy-assisted ultrasonic surgical aspiration of axillary osmidrosis: A retrospective review of 896 consecutive patients from 1998 to 2004
    • Yoo, W. M.; Pae, N. S.; Lee, S. J.; Roh, T. S.; Chung, S.; Tark, K. C. Endoscopy-assisted ultrasonic surgical aspiration of axillary osmidrosis: a retrospective review of 896 consecutive patients from 1998 to 2004. J. Plast. Reconstr. Aesthet. Surg. 2006, 59 (9), 978-982.
    • (2006) J. Plast. Reconstr. Aesthet. Surg. , vol.59 , Issue.9 , pp. 978-982
    • Yoo, W.M.1    Pae, N.S.2    Lee, S.J.3    Roh, T.S.4    Chung, S.5    Tark, K.C.6
  • 40
    • 0037379361 scopus 로고    scopus 로고
    • Apocrine secretory mechanism: Recent findings and unresolved problems
    • Gesase, A. P.; Satoh, Y. Apocrine secretory mechanism: recent findings and unresolved problems. Histol. Histopathol. 2003, 18 (2), 597-608.
    • (2003) Histol. Histopathol. , vol.18 , Issue.2 , pp. 597-608
    • Gesase, A.P.1    Satoh, Y.2
  • 41
    • 0002638882 scopus 로고
    • The effect of topical antibacterial agents on the bacterial flora of the axilla
    • Shehadeh, N. H.; Kligman, A. M. The effect of topical antibacterial agents on the bacterial flora of the axilla. J. Invest. Dermatol. 1963, 40, 61-71.
    • (1963) J. Invest. Dermatol. , vol.40 , pp. 61-71
    • Shehadeh, N.H.1    Kligman, A.M.2
  • 42
    • 0014367402 scopus 로고
    • New advances in the field of androgenic steroidogenesis of the human skin
    • Julesz, M. New advances in the field of androgenic steroidogenesis of the human skin. Acta Med. Acad. Sci. Hung. 1968, 25 (3), 273-285.
    • (1968) Acta Med. Acad. Sci. Hung. , vol.25 , Issue.3 , pp. 273-285
    • Julesz, M.1
  • 43
    • 0014963595 scopus 로고
    • Labelling of steroids in axillary sweat after administration of 3H-delta-5-pregnenolone and 14C-progesterone to a healthy man
    • Brooksbank, B. W. Labelling of steroids in axillary sweat after administration of 3H-delta-5-pregnenolone and 14C-progesterone to a healthy man. Experientia 1970, 26 (9), 1012-1014.
    • (1970) Experientia , vol.26 , Issue.9 , pp. 1012-1014
    • Brooksbank, B.W.1
  • 45
    • 0015237324 scopus 로고
    • Cerumen genetics and human breast cancer
    • Petrakis, N. L. Cerumen genetics and human breast cancer. Science 1971, 173 (994), 347-349.
    • (1971) Science , vol.173 , Issue.994 , pp. 347-349
    • Petrakis, N.L.1
  • 46
    • 0015915582 scopus 로고
    • Evidence against association between wet cerumen and breast cancer
    • Ing, R.; Petrakis, L.; Ho, H. C. Evidence against association between wet cerumen and breast cancer. Lancet 1973, 1 (7793), 41.
    • (1973) Lancet , vol.1 , Issue.7793 , pp. 41
    • Ing, R.1    Petrakis, L.2    Ho, H.C.3
  • 50
    • 0042531890 scopus 로고    scopus 로고
    • MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine
    • Guo, Y.; Kotova, E.; Chen, Z. S.; Lee, K.; Hopper-Borge, E.; Belinsky, M. G.; Kruh, G. D. MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine. J. Biol. Chem. 2003, 278 (32), 29509-29514.
    • (2003) J. Biol. Chem. , vol.278 , Issue.32 , pp. 29509-29514
    • Guo, Y.1    Kotova, E.2    Chen, Z.S.3    Lee, K.4    Hopper-Borge, E.5    Belinsky, M.G.6    Kruh, G.D.7
  • 52
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine
    • Heinemann, V.; Hertel, L. W.; Grindey, G. B.; Plunkett, W. Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1988, 48 (14), 4024-4031.
    • (1988) Cancer Res. , vol.48 , Issue.14 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4


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