GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms

Genomics

Volumn 80, Issue 6, 2002, Pages 553-557

  Wu, Xiaohua ^a   Freeze, Hudson H ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Alternative splicing; Duplication; Glucose transport; GLUT; Testis

Indexed keywords

AMINO ACID; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 4; ISOPROTEIN; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; CHROMOSOME 12P; EVOLUTION; EXON; GENE DUPLICATION; GENOME ANALYSIS; GLUCOSE TRANSPORT; GLYCOSYLATION; HUMAN; MOLECULAR CLONING; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; PSEUDOGENE; SUGAR TRANSPORT; TESTIS;

EID: 0036939298     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2002.7010     Document Type: Article

References (25)

1. Joost, H. G., and Thorens, B. (2001). The extended GLUT-family of sugar/polyol transport facilitators: Nomenclature, sequence characteristics, and potential function of its novel members. Mol. Membr. Biol. 18: 247-256.
2. Olson, A. L., and Pessin, J. E. (1996). Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu. Rev. Nutr. 16: 235-256.
3. Mueckler, M., et al. (1985). Sequence and structure of a human glucose transporter. Science 229: 941-945.
4. Fukumoto, H., et al. (1988). Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein. Proc. Natl. Acad. Sci. USA 85: 5434-5438.
5. Kayano, T., et al. (1990). Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6). J. Biol. Chem. 265: 13276-13282.
6. Fukumoto, H., et al. (1989). Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues. J. Biol. Chem. 264: 7776-7779.
7. Kayano, T., et al. (1988). Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J. Biol. Chem. 263: 15245-15248.
8. Doege, H., Bocianski, A., Joost, H. G., and Schurmann, A. (2000). Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. Biochem. J. 350: 771-776.
9. Doege, H., Schurmann, A., Bahrenberg, G., Brauers, A., and Joost, H. G. (2000). GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity. J. Biol. Chem. 275: 16275-16280.
10. Carayannopoulos, M. O., et al. (2000). GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. Proc. Natl. Acad. Sci. USA 97: 7313-7318.
11. Ibberson, M., Uldry, M., and Thorens, B. (2000). GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J. Biol. Chem. 275: 4607-4612.
12. Phay, J. E., Hussain, H. B., and Moley, J. F. (2000). Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9). Genomics 66: 217-220, doi:10.1006/geno.2000.6195.
13. McVie-Wylie, A. J., Lamson, D. R., and Chen, Y. T. (2001). Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: A candidate gene for NIDDM susceptibility. Genomics 72: 113-117, doi:10.1006/geno.2000.6457.
14. Dawson, P. A., et al. (2001). Sequence and functional analysis of GLUT10: A glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1. Mol. Genet. Metab. 74: 186-199.
15. Doege, H., et al. (2001). Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle. Biochem. J. 359: 443-449.
16. Wu, X., et al. (2002). Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues. Mol. Genet. Metab., in press.
17. Rogers, S., et al. (2002). Identification of a novel glucose transporter-like protein-GLUT-12. Am. J. Physiol. Endocrinol. Metab. 282: E733-738
18. Uldry, M., et al. (2001). Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. EMBO J. 20: 4467-4477.
19. Burant, C. F., Takeda, J., Brot-Laroche, E., Bell, G. I., and Davidson, N. O. (1992). Fructose transporter in human spermatozoa and small intestine is GLUT5. J. Biol. Chem. 267: 14523-14526.
20. Gould, G. W., and Holman, G. D. (1993). The glucose transporter family: Structure, function and tissue-specific expression. Biochem. J. 295: 329-341.
21. Burge, C., and Karlin, S. (1997). Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268: 78-94.
22. Kayano, T., et al. (1988). Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J. Biol. Chem. 263: 15245-15248.
23. Brunet, M. (2002). Hominid from the Upper Miocene of Chad, Central Africa. Nature 418: 145-151.
24. Samonte, R. V., and Eichler, E. E. (2002). Segmental duplications and the evolution of the primate genome. Nat. Rev. Genet. 3: 65-72.
25. Wieczorke, R., et al. (1999). Concurrent knock out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett. 464: 123-128.