SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 14, 2003, Pages 8412-8417

  Li, Hui ^a,b   Myeroff, Lois ^a   Smiraglia, Dominic ^d   Romero, Michael F ^c   Pretlow, Theresa P ^b   Kasturi, Lakshmi ^e   Lutterbaugh, James ^e   Rerko, Ronald M ^e   Casey, Graham ^f   Issa, Jean Pierre ^g   Willis, Joseph ^a,b   Willson, James K V ^a   Plass, Christoph ^d   Markowitz, Sanford D ^a,e  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f LERNER RESEARCH INSTITUTE   (United States)

^g UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Colon cancer

Indexed keywords

AZACITIDINE; COTRANSPORTER;

ANIMAL CELL; ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; CRYPT CELL; CYTOPATHOLOGY; EXON; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE MAPPING; GENE SILENCING; HUMAN; HUMAN CELL; METHYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SLC5A8 GENE; STRUCTURAL HOMOLOGY; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADENOMA; AZACITIDINE; BASE SEQUENCE; CATION TRANSPORT PROTEINS; COLONIC NEOPLASMS; DNA METHYLATION; DNA, NEOPLASM; EXONS; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; INTESTINAL MUCOSA; ION TRANSPORT; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SODIUM; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

ANIMALIA;

EID: 0038153876     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1430846100     Document Type: Article

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