메뉴 건너뛰기




Volumn 5 MAR, Issue , 2014, Pages

Zebrafish in the sea of mineral (iron, zinc, and copper) metabolism

Author keywords

Copper; Iron; Metabolism; Minerals; Trace elements; Zebrafish; Zinc

Indexed keywords

CD71 ANTIGEN; FERRITIN; FERROPORTIN; IODINE; MANGANESE; MEMBRANE PROTEIN; MENKES PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PROTEIN CTR1; PROTEIN ZIP6; PROTEIN ZIP7; SELENIUM; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 84897929048     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00033     Document Type: Review
Times cited : (79)

References (154)
  • 1
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • doi: 10.1074/jbc.M000713200
    • Abboud, S., and Haile, D. J. (2000). A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J. Biol. Chem. 275, 19906-19912. doi: 10.1074/jbc.M000713200.
    • (2000) J. Biol. Chem. , vol.275 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 2
    • 76149093866 scopus 로고    scopus 로고
    • Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease?
    • doi: 10.1523/JNEUROSCI.5255-09.2010
    • Adlard, P. A., Parncutt, J. M., Finkelstein, D. I., and Bush, A. I. (2010). Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease? J. Neurosci. 30, 1631-1636. doi: 10.1523/JNEUROSCI.5255-09.2010.
    • (2010) J. Neurosci. , vol.30 , pp. 1631-1636
    • Adlard, P.A.1    Parncutt, J.M.2    Finkelstein, D.I.3    Bush, A.I.4
  • 3
    • 33846582913 scopus 로고    scopus 로고
    • Wilson's disease
    • doi: 10.1016/S0140-6736(07)60196-2
    • Ala, A., Walker, A. P., Ashkan, K., Dooley, J. S., and Schilsky, M. L. (2007). Wilson's disease. Lancet 369, 397-408. doi: 10.1016/S0140-6736(07)60196-2.
    • (2007) Lancet , vol.369 , pp. 397-408
    • Ala, A.1    Walker, A.P.2    Ashkan, K.3    Dooley, J.S.4    Schilsky, M.L.5
  • 4
    • 79953790695 scopus 로고    scopus 로고
    • Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis
    • doi: 10.1128/MCB.01010-10
    • Amigo, J. D., Yu, M., Troadec, M. B., Gwynn, B., Cooney, J. D., Lambert, A. J., et al. (2011). Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Mol. Cell. Biol. 31, 1344-1356. doi: 10.1128/MCB.01010-10.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 1344-1356
    • Amigo, J.D.1    Yu, M.2    Troadec, M.B.3    Gwynn, B.4    Cooney, J.D.5    Lambert, A.J.6
  • 5
    • 0032573579 scopus 로고    scopus 로고
    • Zebrafish hox clusters and vertebrate genome evolution
    • doi: 10.1126/science.282.5394.1711
    • Amores, A., Force, A., Yan, Y. L., Joly, L., Amemiya, C., Fritz, A., et al. (1998). Zebrafish hox clusters and vertebrate genome evolution. Science 282, 1711-1714. doi: 10.1126/science.282.5394.1711.
    • (1998) Science , vol.282 , pp. 1711-1714
    • Amores, A.1    Force, A.2    Yan, Y.L.3    Joly, L.4    Amemiya, C.5    Fritz, A.6
  • 6
    • 8444252173 scopus 로고    scopus 로고
    • Mouse zinc transporter 1 gene provides an essential function during early embryonic development
    • doi: 10.1002/gene.20067
    • Andrews, G. K., Wang, H., Dey, S. K., and Palmiter, R. D. (2004). Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis 40, 74-81. doi: 10.1002/gene.20067.
    • (2004) Genesis , vol.40 , pp. 74-81
    • Andrews, G.K.1    Wang, H.2    Dey, S.K.3    Palmiter, R.D.4
  • 7
    • 0033799583 scopus 로고    scopus 로고
    • The syntenic relationship of the zebrafish and human genomes
    • doi: 10.1101/gr.144700
    • Barbazuk, W. B., Korf, I., Kadavi, C., Heyen, J., Tate, S., Wun, E., et al. (2000). The syntenic relationship of the zebrafish and human genomes. Genome Res. 10, 1351-1358. doi: 10.1101/gr.144700.
    • (2000) Genome Res. , vol.10 , pp. 1351-1358
    • Barbazuk, W.B.1    Korf, I.2    Kadavi, C.3    Heyen, J.4    Tate, S.5    Wun, E.6
  • 8
    • 78751558997 scopus 로고    scopus 로고
    • Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice
    • doi: 10.1182/blood-2010-05-287359
    • Bartnikas, T. B., Andrews, N. C., and Fleming, M. D. (2011). Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice. Blood 117, 630-637. doi: 10.1182/blood-2010-05-287359.
    • (2011) Blood , vol.117 , pp. 630-637
    • Bartnikas, T.B.1    Andrews, N.C.2    Fleming, M.D.3
  • 9
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • doi: 10.1038/35000034
    • Batlle, E., Sancho, E., Franci, C., Dominguez, D., Monfar, M., Baulida, J., et al. (2000). The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2, 84-89. doi: 10.1038/35000034.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5    Baulida, J.6
  • 10
    • 84868118216 scopus 로고    scopus 로고
    • Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia)
    • doi: 10.1371/journal.pone.0048679
    • Beker Aydemir, T., Chang, S. M., Guthrie, G. J., Maki, A. B., Ryu, M. S., Karabiyik, A., et al. (2012). Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia). PLoS ONE 7:e48679. doi: 10.1371/journal.pone.0048679.
    • (2012) PLoS ONE , vol.7
    • Beker Aydemir, T.1    Chang, S.M.2    Guthrie, G.J.3    Maki, A.B.4    Ryu, M.S.5    Karabiyik, A.6
  • 12
    • 0030700525 scopus 로고    scopus 로고
    • The role of thyroid hormone in zebrafish and axolotl development
    • doi: 10.1073/pnas.94.24.13011
    • Brown, D. D. (1997). The role of thyroid hormone in zebrafish and axolotl development. Proc. Natl. Acad. Sci. U.S.A. 94, 13011-13016. doi: 10.1073/pnas.94.24.13011.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 13011-13016
    • Brown, D.D.1
  • 13
    • 0032878550 scopus 로고    scopus 로고
    • Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation
    • doi: 10.1093/hmg/8.9.1665
    • Buiakova, O. I., Xu, J., Lutsenko, S., Zeitlin, S., Das, K., Das, S., et al. (1999). Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation. Hum. Mol. Genet. 8, 1665-1671. doi: 10.1093/hmg/8.9.1665.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1665-1671
    • Buiakova, O.I.1    Xu, J.2    Lutsenko, S.3    Zeitlin, S.4    Das, K.5    Das, S.6
  • 14
    • 0142135117 scopus 로고    scopus 로고
    • Waterborne iron acquisition by a freshwater teleost fish, zebrafish Danio rerio
    • doi: 10.1242/jeb.00584
    • Bury, N. R., and Grosell, M. (2003). Waterborne iron acquisition by a freshwater teleost fish, zebrafish Danio rerio. J. Exp. Biol. 206, 3529-3535. doi: 10.1242/jeb.00584.
    • (2003) J. Exp. Biol. , vol.206 , pp. 3529-3535
    • Bury, N.R.1    Grosell, M.2
  • 15
    • 34548013116 scopus 로고    scopus 로고
    • The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload
    • doi: 10.1182/blood-2007-02-072520
    • Camaschella, C., Campanella, A., De Falco, L., Boschetto, L., Merlini, R., Silvestri, L., et al. (2007). The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload. Blood 110, 1353-1358. doi: 10.1182/blood-2007-02-072520.
    • (2007) Blood , vol.110 , pp. 1353-1358
    • Camaschella, C.1    Campanella, A.2    De Falco, L.3    Boschetto, L.4    Merlini, R.5    Silvestri, L.6
  • 16
    • 46249105799 scopus 로고    scopus 로고
    • Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells
    • doi: 10.1042/BJ20071471
    • Canales, J., Fernandez, A., Ribeiro, J. M., Cabezas, A., Rodrigues, J. R., Cameselle, J. C., et al. (2008). Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells. Biochem. J. 413, 103-113. doi: 10.1042/BJ20071471.
    • (2008) Biochem. J. , vol.413 , pp. 103-113
    • Canales, J.1    Fernandez, A.2    Ribeiro, J.M.3    Cabezas, A.4    Rodrigues, J.R.5    Cameselle, J.C.6
  • 17
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • doi: 10.1038/35000025
    • Cano, A., Perez-Moreno, M. A., Rodrigo, I., Locascio, A., Blanco, M. J., Del Barrio, M. G., et al. (2000). The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2, 76-83. doi: 10.1038/35000025.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 18
    • 0037071383 scopus 로고    scopus 로고
    • Transcriptional regulation of erythropoiesis: an affair involving multiple partners
    • doi: 10.1038/sj.onc.1205326
    • Cantor, A. B., and Orkin, S. H. (2002). Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 21, 3368-3376. doi: 10.1038/sj.onc.1205326.
    • (2002) Oncogene , vol.21 , pp. 3368-3376
    • Cantor, A.B.1    Orkin, S.H.2
  • 19
    • 1242321034 scopus 로고    scopus 로고
    • Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution
    • doi: 10.1038/sj.embor.7400036
    • Castellano, S., Novoselov, S. V., Kryukov, G. V., Lescure, A., Blanco, E., Krol, A., et al. (2004). Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution. EMBO Rep. 5, 71-77. doi: 10.1038/sj.embor.7400036.
    • (2004) EMBO Rep. , vol.5 , pp. 71-77
    • Castellano, S.1    Novoselov, S.V.2    Kryukov, G.V.3    Lescure, A.4    Blanco, E.5    Krol, A.6
  • 21
    • 79551553885 scopus 로고    scopus 로고
    • Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status
    • doi: 10.1016/j.cbi.2010.12.003
    • Chen, H. R., Yang, H. C., Hsieh, D. J., Liu, Z., and Tsai, K. J. (2011). Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status. Chem. Biol. Interact. 189, 192-197. doi: 10.1016/j.cbi.2010.12.003.
    • (2011) Chem. Biol. Interact. , vol.189 , pp. 192-197
    • Chen, H.R.1    Yang, H.C.2    Hsieh, D.J.3    Liu, Z.4    Tsai, K.J.5
  • 22
    • 33645070287 scopus 로고    scopus 로고
    • Unexpected role of ceruloplasmin in intestinal iron absorption
    • doi: 10.1016/j.cmet.2005.10.003
    • Cherukuri, S., Potla, R., Sarkar, J., Nurko, S., Harris, Z. L., and Fox, P. L. (2005). Unexpected role of ceruloplasmin in intestinal iron absorption. Cell Metab. 2, 309-319. doi: 10.1016/j.cmet.2005.10.003.
    • (2005) Cell Metab. , vol.2 , pp. 309-319
    • Cherukuri, S.1    Potla, R.2    Sarkar, J.3    Nurko, S.4    Harris, Z.L.5    Fox, P.L.6
  • 23
    • 0033574071 scopus 로고    scopus 로고
    • Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene
    • doi: 10.1073/pnas.96.4.1716
    • Cole, T. B., Wenzel, H. J., Kafer, K. E., Schwartzkroin, P. A., and Palmiter, R. D. (1999). Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proc. Natl. Acad. Sci. U.S.A. 96, 1716-1721. doi: 10.1073/pnas.96.4.1716.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 1716-1721
    • Cole, T.B.1    Wenzel, H.J.2    Kafer, K.E.3    Schwartzkroin, P.A.4    Palmiter, R.D.5
  • 24
    • 33746375021 scopus 로고    scopus 로고
    • The effects of dietary iron concentration on gastrointestinal and branchial assimilation of both iron and cadmium in zebrafish (Danio rerio)
    • doi: 10.1016/j.aquatox.2006.06.008
    • Cooper, C. A., Handy, R. D., and Bury, N. R. (2006). The effects of dietary iron concentration on gastrointestinal and branchial assimilation of both iron and cadmium in zebrafish (Danio rerio). Aquat. Toxicol. 79, 167-175. doi: 10.1016/j.aquatox.2006.06.008.
    • (2006) Aquat. Toxicol. , vol.79 , pp. 167-175
    • Cooper, C.A.1    Handy, R.D.2    Bury, N.R.3
  • 25
    • 0035232015 scopus 로고    scopus 로고
    • Lysyl oxidases: a novel multifunctional amine oxidase family
    • doi: 10.1016/S0079-6603(01)70012-8
    • Csiszar, K. (2001). Lysyl oxidases: a novel multifunctional amine oxidase family. Prog. Nucleic Acid Res. Mol. Biol. 70, 1-32. doi: 10.1016/S0079-6603(01)70012-8.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol. , vol.70 , pp. 1-32
    • Csiszar, K.1
  • 26
    • 0028010889 scopus 로고
    • Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport
    • doi: 10.1016/0092-8674(94)90345-X
    • Dancis, A., Yuan, D. S., Haile, D., Askwith, C., Eide, D., Moehle, C., et al. (1994). Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76, 393-402. doi: 10.1016/0092-8674(94)90345-X.
    • (1994) Cell , vol.76 , pp. 393-402
    • Dancis, A.1    Yuan, D.S.2    Haile, D.3    Askwith, C.4    Eide, D.5    Moehle, C.6
  • 27
    • 70349237065 scopus 로고    scopus 로고
    • Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage
    • doi: 10.1002/hep.23058
    • Darshan, D., Vanoaica, L., Richman, L., Beermann, F., and Kuhn, L. C. (2009). Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage. Hepatology 50, 852-860. doi: 10.1002/hep.23058.
    • (2009) Hepatology , vol.50 , pp. 852-860
    • Darshan, D.1    Vanoaica, L.2    Richman, L.3    Beermann, F.4    Kuhn, L.C.5
  • 28
    • 33746961666 scopus 로고    scopus 로고
    • Molecular and clinical correlates in iron overload associated with mutations in ferroportin
    • De Domenico, I., McVey Ward, D., Nemeth, E., Ganz, T., Corradini, E., Ferrara, F., et al. (2006). Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica 91, 1092-1095.
    • (2006) Haematologica , vol.91 , pp. 1092-1095
    • De Domenico, I.1    McVey Ward, D.2    Nemeth, E.3    Ganz, T.4    Corradini, E.5    Ferrara, F.6
  • 29
    • 36349020323 scopus 로고    scopus 로고
    • Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations
    • doi: 10.1182/blood-2007-07-100248
    • De Domenico, I., Vaughn, M. B., Yoon, D., Kushner, J. P., Ward, D. M., and Kaplan, J. (2007). Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations. Blood 110, 3780-3783. doi: 10.1182/blood-2007-07-100248.
    • (2007) Blood , vol.110 , pp. 3780-3783
    • De Domenico, I.1    Vaughn, M.B.2    Yoon, D.3    Kushner, J.P.4    Ward, D.M.5    Kaplan, J.6
  • 31
    • 33845784175 scopus 로고    scopus 로고
    • Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo
    • doi: 10.1016/j.yexcr.2006.10.005
    • Deniziak, M., Thisse, C., Rederstorff, M., Hindelang, C., Thisse, B., and Lescure, A. (2007). Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo. Exp. Cell Res. 313, 156-167. doi: 10.1016/j.yexcr.2006.10.005.
    • (2007) Exp. Cell Res. , vol.313 , pp. 156-167
    • Deniziak, M.1    Thisse, C.2    Rederstorff, M.3    Hindelang, C.4    Thisse, B.5    Lescure, A.6
  • 32
    • 77953690176 scopus 로고    scopus 로고
    • A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production
    • doi: 10.1016/j.cell.2010.04.040
    • Devireddy, L. R., Hart, D. O., Goetz, D. H., and Green, M. R. (2010). A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production. Cell 141, 1006-1017. doi: 10.1016/j.cell.2010.04.040.
    • (2010) Cell , vol.141 , pp. 1006-1017
    • Devireddy, L.R.1    Hart, D.O.2    Goetz, D.H.3    Green, M.R.4
  • 33
    • 0037114751 scopus 로고    scopus 로고
    • The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1)
    • doi: 10.1182/blood-2002-04-1169
    • Donovan, A., Brownlie, A., Dorschner, M. O., Zhou, Y., Pratt, S. J., Paw, B. H., et al. (2002). The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood 100, 4655-4659. doi: 10.1182/blood-2002-04-1169.
    • (2002) Blood , vol.100 , pp. 4655-4659
    • Donovan, A.1    Brownlie, A.2    Dorschner, M.O.3    Zhou, Y.4    Pratt, S.J.5    Paw, B.H.6
  • 34
    • 0034677467 scopus 로고    scopus 로고
    • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
    • doi: 10.1038/35001596
    • Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., et al. (2000). Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403, 776-781. doi: 10.1038/35001596.
    • (2000) Nature , vol.403 , pp. 776-781
    • Donovan, A.1    Brownlie, A.2    Zhou, Y.3    Shepard, J.4    Pratt, S.J.5    Moynihan, J.6
  • 35
    • 20444416123 scopus 로고    scopus 로고
    • The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
    • doi: 10.1016/j.cmet.2005.01.003
    • Donovan, A., Lima, C. A., Pinkus, J. L., Pinkus, G. S., Zon, L. I., Robine, S., et al. (2005). The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 1, 191-200. doi: 10.1016/j.cmet.2005.01.003.
    • (2005) Cell Metab. , vol.1 , pp. 191-200
    • Donovan, A.1    Lima, C.A.2    Pinkus, J.L.3    Pinkus, G.S.4    Zon, L.I.5    Robine, S.6
  • 37
    • 33745040492 scopus 로고    scopus 로고
    • 3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy
    • doi: 10.1002/dvg.20211
    • 3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy. Genesis 44, 239-251. doi: 10.1002/dvg.20211.
    • (2006) Genesis , vol.44 , pp. 239-251
    • Dufner-Beattie, J.1    Huang, Z.L.2    Geiser, J.3    Xu, W.4    Andrews, G.K.5
  • 38
    • 34347352057 scopus 로고    scopus 로고
    • The mouse acrodermatitis enteropathica gene Slc39a4 (Zip4) is essential for early development and heterozygosity causes hypersensitivity to zinc deficiency
    • doi: 10.1093/hmg/ddm088
    • Dufner-Beattie, J., Weaver, B. P., Geiser, J., Bilgen, M., Larson, M., Xu, W., et al. (2007). The mouse acrodermatitis enteropathica gene Slc39a4 (Zip4) is essential for early development and heterozygosity causes hypersensitivity to zinc deficiency. Hum. Mol. Genet. 16, 1391-1399. doi: 10.1093/hmg/ddm088.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 1391-1399
    • Dufner-Beattie, J.1    Weaver, B.P.2    Geiser, J.3    Bilgen, M.4    Larson, M.5    Xu, W.6
  • 39
    • 33144470760 scopus 로고    scopus 로고
    • The phylogeny of teleost ZIP and ZnT zinc transporters and their tissue specific expression and response to zinc in zebrafish
    • doi: 10.1016/j.bbaexp.2005.12.002
    • Feeney, G. P., Zheng, D., Kille, P., and Hogstrand, C. (2005). The phylogeny of teleost ZIP and ZnT zinc transporters and their tissue specific expression and response to zinc in zebrafish. Biochim. Biophys. Acta 1732, 88-95. doi: 10.1016/j.bbaexp.2005.12.002.
    • (2005) Biochim. Biophys. Acta , vol.1732 , pp. 88-95
    • Feeney, G.P.1    Zheng, D.2    Kille, P.3    Hogstrand, C.4
  • 40
    • 0032477866 scopus 로고    scopus 로고
    • Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport
    • doi: 10.1073/pnas.95.3.1148
    • Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D., and Andrews, N. C. (1998). Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc. Natl. Acad. Sci. U.S.A. 95, 1148-1153. doi: 10.1073/pnas.95.3.1148.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1148-1153
    • Fleming, M.D.1    Romano, M.A.2    Su, M.A.3    Garrick, L.M.4    Garrick, M.D.5    Andrews, N.C.6
  • 41
    • 0030763856 scopus 로고    scopus 로고
    • Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
    • doi: 10.1038/ng0897-383
    • Fleming, M. D., Trenor, C. C., 3rd., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., et al. (1997). Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat. Genet. 16, 383-386. doi: 10.1038/ng0897-383.
    • (1997) Nat. Genet. , vol.16 , pp. 383-386
    • Fleming, M.D.1    Trenor III, C.C.2    Su, M.A.3    Foernzler, D.4    Beier, D.R.5    Dietrich, W.F.6
  • 42
    • 0037025331 scopus 로고    scopus 로고
    • Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
    • doi: 10.1074/jbc.M111789200
    • Foury, F., and Roganti, T. (2002). Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J. Biol. Chem. 277, 24475-24483. doi: 10.1074/jbc.M111789200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24475-24483
    • Foury, F.1    Roganti, T.2
  • 43
    • 63849158505 scopus 로고    scopus 로고
    • Transferrin-a modulates hepcidin expression in zebrafish embryos
    • doi: 10.1182/blood-2008-06-165340
    • Fraenkel, P. G., Gibert, Y., Holzheimer, J. L., Lattanzi, V. J., Burnett, S. F., Dooley, K. A., et al. (2009). Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood 113, 2843-2850. doi: 10.1182/blood-2008-06-165340.
    • (2009) Blood , vol.113 , pp. 2843-2850
    • Fraenkel, P.G.1    Gibert, Y.2    Holzheimer, J.L.3    Lattanzi, V.J.4    Burnett, S.F.5    Dooley, K.A.6
  • 44
    • 20444464809 scopus 로고    scopus 로고
    • Ferroportin1 is required for normal iron cycling in zebrafish
    • doi: 10.1172/JCI23780
    • Fraenkel, P. G., Traver, D., Donovan, A., Zahrieh, D., and Zon, L. I. (2005). Ferroportin1 is required for normal iron cycling in zebrafish. J. Clin. Invest. 115, 1532-1541. doi: 10.1172/JCI23780.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1532-1541
    • Fraenkel, P.G.1    Traver, D.2    Donovan, A.3    Zahrieh, D.4    Zon, L.I.5
  • 45
    • 24044480992 scopus 로고    scopus 로고
    • Relevance, essentiality and toxicity of trace elements in human health
    • doi: 10.1016/j.mam.2005.07.013
    • Fraga, C. G. (2005). Relevance, essentiality and toxicity of trace elements in human health. Mol. Aspects. Med. 26, 235-244. doi: 10.1016/j.mam.2005.07.013.
    • (2005) Mol. Aspects. Med. , vol.26 , pp. 235-244
    • Fraga, C.G.1
  • 46
    • 56649111126 scopus 로고    scopus 로고
    • The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways
    • doi: 10.1371/journal.pone.0003642
    • Fukada, T., Civic, N., Furuichi, T., Shimoda, S., Mishima, K., Higashiyama, H., et al. (2008). The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways. PLoS ONE 3:e3642. doi: 10.1371/journal.pone.0003642.
    • (2008) PLoS ONE , vol.3
    • Fukada, T.1    Civic, N.2    Furuichi, T.3    Shimoda, S.4    Mishima, K.5    Higashiyama, H.6
  • 47
    • 0035933885 scopus 로고    scopus 로고
    • The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells
    • doi: 10.1074/jbc.M101772200
    • Gaither, L. A., and Eide, D. J. (2001). The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells. J. Biol. Chem. 276, 22258-22264. doi: 10.1074/jbc.M101772200.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22258-22264
    • Gaither, L.A.1    Eide, D.J.2
  • 48
    • 70350646902 scopus 로고    scopus 로고
    • Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
    • doi: 10.1038/ng.466
    • Ganesh, S. K., Zakai, N. A., Van Rooij, F. J., Soranzo, N., Smith, A. V., Nalls, M. A., et al. (2009). Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat. Genet. 41, 1191-1198. doi: 10.1038/ng.466.
    • (2009) Nat. Genet. , vol.41 , pp. 1191-1198
    • Ganesh, S.K.1    Zakai, N.A.2    Van Rooij, F.J.3    Soranzo, N.4    Smith, A.V.5    Nalls, M.A.6
  • 49
    • 34347241358 scopus 로고    scopus 로고
    • Essential role of lysyl oxidases in notochord development
    • doi: 10.1016/j.ydbio.2007.04.029
    • Gansner, J. M., Mendelsohn, B. A., Hultman, K. A., Johnson, S. L., and Gitlin, J. D. (2007). Essential role of lysyl oxidases in notochord development. Dev. Biol. 307, 202-213. doi: 10.1016/j.ydbio.2007.04.029.
    • (2007) Dev. Biol. , vol.307 , pp. 202-213
    • Gansner, J.M.1    Mendelsohn, B.A.2    Hultman, K.A.3    Johnson, S.L.4    Gitlin, J.D.5
  • 50
    • 84864057714 scopus 로고    scopus 로고
    • A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity
    • doi: 10.1371/journal.pgen.1002766
    • Geiser, J., Venken, K. J., De Lisle, R. C., and Andrews, G. K. (2012). A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity. PLoS Genet. 8:e1002766. doi: 10.1371/journal.pgen.1002766.
    • (2012) PLoS Genet. , vol.8
    • Geiser, J.1    Venken, K.J.2    De Lisle, R.C.3    Andrews, G.K.4
  • 51
    • 0034585942 scopus 로고    scopus 로고
    • Biochemical and genetic defects underlying human congenital hypotransferrinemia
    • doi: 10.1038/sj/thj/6200063
    • Goldwurm, S., Casati, C., Venturi, N., Strada, S., Santambrogio, P., Indraccolo, S., et al. (2000). Biochemical and genetic defects underlying human congenital hypotransferrinemia. Hematol. J. 1, 390-398. doi: 10.1038/sj/thj/6200063.
    • (2000) Hematol. J. , vol.1 , pp. 390-398
    • Goldwurm, S.1    Casati, C.2    Venturi, N.3    Strada, S.4    Santambrogio, P.5    Indraccolo, S.6
  • 52
    • 18244399587 scopus 로고    scopus 로고
    • Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
    • doi: 10.1172/JCI24356
    • Gunshin, H., Fujiwara, Y., Custodio, A. O., Direnzo, C., Robine, S., and Andrews, N. C. (2005a). Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J. Clin. Invest. 115, 1258-1266. doi: 10.1172/JCI24356.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1258-1266
    • Gunshin, H.1    Fujiwara, Y.2    Custodio, A.O.3    Direnzo, C.4    Robine, S.5    Andrews, N.C.6
  • 53
    • 0030755366 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian proton-coupled metal-ion transporter
    • doi: 10.1038/41343
    • Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., et al. (1997). Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388, 482-488. doi: 10.1038/41343.
    • (1997) Nature , vol.388 , pp. 482-488
    • Gunshin, H.1    Mackenzie, B.2    Berger, U.V.3    Gunshin, Y.4    Romero, M.F.5    Boron, W.F.6
  • 54
    • 27144507493 scopus 로고    scopus 로고
    • Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice
    • doi: 10.1182/blood-2005-02-0716
    • Gunshin, H., Starr, C. N., Direnzo, C., Fleming, M. D., Jin, J., Greer, E. L., et al. (2005b). Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. Blood 106, 2879-2883. doi: 10.1182/blood-2005-02-0716.
    • (2005) Blood , vol.106 , pp. 2879-2883
    • Gunshin, H.1    Starr, C.N.2    Direnzo, C.3    Fleming, M.D.4    Jin, J.5    Greer, E.L.6
  • 55
    • 12644303221 scopus 로고    scopus 로고
    • The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
    • Haffter, P., Granato, M., Brand, M., Mullins, M. C., Hammerschmidt, M., Kane, D. A., et al. (1996). The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123, 1-36.
    • (1996) Development , vol.123 , pp. 1-36
    • Haffter, P.1    Granato, M.2    Brand, M.3    Mullins, M.C.4    Hammerschmidt, M.5    Kane, D.A.6
  • 56
    • 0035811058 scopus 로고    scopus 로고
    • The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis
    • doi: 10.1073/pnas.111058498
    • Hamza, I., Faisst, A., Prohaska, J., Chen, J., Gruss, P., and Gitlin, J. D. (2001). The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis. Proc. Natl. Acad. Sci. U.S.A. 98, 6848-6852. doi: 10.1073/pnas.111058498.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 6848-6852
    • Hamza, I.1    Faisst, A.2    Prohaska, J.3    Chen, J.4    Gruss, P.5    Gitlin, J.D.6
  • 57
    • 0032875387 scopus 로고    scopus 로고
    • Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
    • doi: 10.1073/pnas.96.19.10812
    • Harris, Z. L., Durley, A. P., Man, T. K., and Gitlin, J. D. (1999). Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc. Natl. Acad. Sci. U.S.A. 96, 10812-10817. doi: 10.1073/pnas.96.19.10812.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 10812-10817
    • Harris, Z.L.1    Durley, A.P.2    Man, T.K.3    Gitlin, J.D.4
  • 58
    • 0027360042 scopus 로고
    • Studies on familial hypotransferrinemia: unique clinical course and molecular pathology
    • Hayashi, A., Wada, Y., Suzuki, T., and Shimizu, A. (1993). Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am. J. Hum. Genet. 53, 201-213.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 201-213
    • Hayashi, A.1    Wada, Y.2    Suzuki, T.3    Shimizu, A.4
  • 60
    • 79952977920 scopus 로고    scopus 로고
    • The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth
    • doi: 10.1371/journal.pone.0018059
    • Hojyo, S., Fukada, T., Shimoda, S., Ohashi, W., Bin, B. H., Koseki, H., et al. (2011). The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth. PLoS ONE 6:e18059. doi: 10.1371/journal.pone.0018059.
    • (2011) PLoS ONE , vol.6
    • Hojyo, S.1    Fukada, T.2    Shimoda, S.3    Ohashi, W.4    Bin, B.H.5    Koseki, H.6
  • 62
    • 0030724951 scopus 로고    scopus 로고
    • A novel gene involved in zinc transport is deficient in the lethal milk mouse
    • doi: 10.1038/ng1197-292
    • Huang, L., and Gitschier, J. (1997). A novel gene involved in zinc transport is deficient in the lethal milk mouse. Nat. Genet. 17, 292-297. doi: 10.1038/ng1197-292.
    • (1997) Nat. Genet. , vol.17 , pp. 292-297
    • Huang, L.1    Gitschier, J.2
  • 63
    • 17644400171 scopus 로고    scopus 로고
    • The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus
    • doi: 10.1074/jbc.M412188200
    • Huang, L., Kirschke, C. P., Zhang, Y., and Yu, Y. Y. (2005b). The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus. J. Biol. Chem. 280, 15456-15463. doi: 10.1074/jbc.M412188200.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15456-15463
    • Huang, L.1    Kirschke, C.P.2    Zhang, Y.3    Yu, Y.Y.4
  • 64
    • 84875196486 scopus 로고    scopus 로고
    • The SLC30 family of zinc transporters-a review of current understanding of their biological and pathophysiological roles
    • doi: 10.1016/j.mam.2012.05.008
    • Huang, L., and Tepaamorndech, S. (2013). The SLC30 family of zinc transporters-a review of current understanding of their biological and pathophysiological roles. Mol. Aspects Med. 34, 548-560. doi: 10.1016/j.mam.2012.05.008.
    • (2013) Mol. Aspects Med. , vol.34 , pp. 548-560
    • Huang, L.1    Tepaamorndech, S.2
  • 65
    • 37549048234 scopus 로고    scopus 로고
    • Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation
    • doi: 10.1074/jbc.M706631200
    • Huang, L., Yu, Y. Y., Kirschke, C. P., Gertz, E. R., and Lloyd, K. K. (2007). Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation. J. Biol. Chem. 282, 37053-37063. doi: 10.1074/jbc.M706631200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 37053-37063
    • Huang, L.1    Yu, Y.Y.2    Kirschke, C.P.3    Gertz, E.R.4    Lloyd, K.K.5
  • 66
    • 0016330759 scopus 로고
    • Primary defect in copper transport underlies mottled mutants in the mouse
    • doi: 10.1038/249852a0
    • Hunt, D. M. (1974). Primary defect in copper transport underlies mottled mutants in the mouse. Nature 249, 852-854. doi: 10.1038/249852a0.
    • (1974) Nature , vol.249 , pp. 852-854
    • Hunt, D.M.1
  • 67
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group H. The Huntington's Disease Collaborative Research Group. doi: 10.1016/0092-8674(93)90585-E
    • Huntington's Disease Collaborative Research Group, H. (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell 72, 971-983. doi: 10.1016/0092-8674(93)90585-E.
    • (1993) Cell , vol.72 , pp. 971-983
  • 68
    • 0037098959 scopus 로고    scopus 로고
    • Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5
    • doi: 10.1093/hmg/11.15.1775
    • Inoue, K., Matsuda, K., Itoh, M., Kawaguchi, H., Tomoike, H., Aoyagi, T., et al. (2002). Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum. Mol. Genet 11, 1775-1784. doi: 10.1093/hmg/11.15.1775.
    • (2002) Hum. Mol. Genet , vol.11 , pp. 1775-1784
    • Inoue, K.1    Matsuda, K.2    Itoh, M.3    Kawaguchi, H.4    Tomoike, H.5    Aoyagi, T.6
  • 69
    • 77956512193 scopus 로고    scopus 로고
    • Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation
    • doi: 10.1242/dmm.005769
    • Ishizaki, H., Spitzer, M., Wildenhain, J., Anastasaki, C., Zeng, Z., Dolma, S., et al. (2010). Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis. Model Mech. 3, 639-651. doi: 10.1242/dmm.005769.
    • (2010) Dis. Model Mech. , vol.3 , pp. 639-651
    • Ishizaki, H.1    Spitzer, M.2    Wildenhain, J.3    Anastasaki, C.4    Zeng, Z.5    Dolma, S.6
  • 70
    • 84875129764 scopus 로고    scopus 로고
    • The SLC39 family of zinc transporters
    • doi: 10.1016/j.mam.2012.05.011
    • Jeong, J., and Eide, D. J. (2013). The SLC39 family of zinc transporters. Mol. Aspects Med. 34, 612-619. doi: 10.1016/j.mam.2012.05.011.
    • (2013) Mol. Aspects Med. , vol.34 , pp. 612-619
    • Jeong, J.1    Eide, D.J.2
  • 71
    • 0034485414 scopus 로고    scopus 로고
    • Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues
    • doi: 10.1046/j.1365-2443.2000.00392.x
    • Kryukov, G. V., and Gladyshev, V. N. (2000). Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues. Genes Cells 5, 1049-1060. doi: 10.1046/j.1365-2443.2000.00392.x.
    • (2000) Genes Cells , vol.5 , pp. 1049-1060
    • Kryukov, G.V.1    Gladyshev, V.N.2
  • 72
    • 0037174814 scopus 로고    scopus 로고
    • Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system
    • doi: 10.1074/jbc.M208002200
    • Lee, J., Petris, M. J., and Thiele, D. J. (2002). Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system. J. Biol. Chem. 277, 40253-40259. doi: 10.1074/jbc.M208002200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40253-40259
    • Lee, J.1    Petris, M.J.2    Thiele, D.J.3
  • 73
    • 0035811053 scopus 로고    scopus 로고
    • Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development
    • doi: 10.1073/pnas.111058698
    • Lee, J., Prohaska, J. R., and Thiele, D. J. (2001). Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc. Natl. Acad. Sci. U.S.A. 98, 6842-6847. doi: 10.1073/pnas.111058698.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 6842-6847
    • Lee, J.1    Prohaska, J.R.2    Thiele, D.J.3
  • 74
    • 33745752870 scopus 로고    scopus 로고
    • Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis
    • doi: 10.1182/blood-2006-02-003376
    • Lesbordes-Brion, J. C., Viatte, L., Bennoun, M., Lou, D. Q., Ramey, G., Houbron, C., et al. (2006). Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis. Blood 108, 1402-1405. doi: 10.1182/blood-2006-02-003376.
    • (2006) Blood , vol.108 , pp. 1402-1405
    • Lesbordes-Brion, J.C.1    Viatte, L.2    Bennoun, M.3    Lou, D.Q.4    Ramey, G.5    Houbron, C.6
  • 75
  • 76
    • 0028247206 scopus 로고
    • The mottled gene is the mouse homologue of the Menkes disease gene
    • doi: 10.1038/ng0494-369
    • Levinson, B., Vulpe, C., Elder, B., Martin, C., Verley, F., Packman, S., et al. (1994). The mottled gene is the mouse homologue of the Menkes disease gene. Nat. Genet. 6, 369-373. doi: 10.1038/ng0494-369.
    • (1994) Nat. Genet. , vol.6 , pp. 369-373
    • Levinson, B.1    Vulpe, C.2    Elder, B.3    Martin, C.4    Verley, F.5    Packman, S.6
  • 77
    • 0032959574 scopus 로고    scopus 로고
    • Transferrin receptor is necessary for development of erythrocytes and the nervous system
    • doi: 10.1038/7727
    • Levy, J. E., Jin, O., Fujiwara, Y., Kuo, F., and Andrews, N. C. (1999). Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat. Genet. 21, 396-399. doi: 10.1038/7727.
    • (1999) Nat. Genet. , vol.21 , pp. 396-399
    • Levy, J.E.1    Jin, O.2    Fujiwara, Y.3    Kuo, F.4    Andrews, N.C.5
  • 78
    • 79959589568 scopus 로고    scopus 로고
    • MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction
    • doi: 10.1371/journal.pone.0021526
    • Lichten, L. A., Ryu, M. S., Guo, L., Embury, J., and Cousins, R. J. (2011). MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction. PLoS ONE 6:e21526. doi: 10.1371/journal.pone.0021526.
    • (2011) PLoS ONE , vol.6
    • Lichten, L.A.1    Ryu, M.S.2    Guo, L.3    Embury, J.4    Cousins, R.J.5
  • 79
    • 67650477815 scopus 로고    scopus 로고
    • Characterization, molecular modelling and developmental expression of zebrafish manganese superoxide dismutase
    • doi: 10.1016/j.fsi.2009.05.015
    • Lin, C. T., Tseng, W. C., Hsiao, N. W., Chang, H. H., and Ken, C. F. (2009). Characterization, molecular modelling and developmental expression of zebrafish manganese superoxide dismutase. Fish Shellfish Immunol. 27, 318-324. doi: 10.1016/j.fsi.2009.05.015.
    • (2009) Fish Shellfish Immunol. , vol.27 , pp. 318-324
    • Lin, C.T.1    Tseng, W.C.2    Hsiao, N.W.3    Chang, H.H.4    Ken, C.F.5
  • 80
    • 34548406422 scopus 로고    scopus 로고
    • Huntingtin-deficient zebrafish exhibit defects in iron utilization and development
    • doi: 10.1093/hmg/ddm138
    • Lumsden, A. L., Henshall, T. L., Dayan, S., Lardelli, M. T., and Richards, R. I. (2007). Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Hum. Mol. Genet. 16, 1905-1920. doi: 10.1093/hmg/ddm138.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 1905-1920
    • Lumsden, A.L.1    Henshall, T.L.2    Dayan, S.3    Lardelli, M.T.4    Richards, R.I.5
  • 81
    • 77949917893 scopus 로고    scopus 로고
    • Human copper homeostasis: a network of interconnected pathways
    • doi: 10.1016/j.cbpa.2010.01.003
    • Lutsenko, S. (2010). Human copper homeostasis: a network of interconnected pathways. Curr. Opin. Chem. Biol. 14, 211-217. doi: 10.1016/j.cbpa.2010.01.003.
    • (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 211-217
    • Lutsenko, S.1
  • 82
    • 1542500529 scopus 로고    scopus 로고
    • Cloning, expression pattern and essentiality of the high-affinity copper transporter 1 (ctr1) gene in zebrafish
    • doi: 10.1016/j.gene.2003.11.019
    • Mackenzie, N. C., Brito, M., Reyes, A. E., and Allende, M. L. (2004). Cloning, expression pattern and essentiality of the high-affinity copper transporter 1 (ctr1) gene in zebrafish. Gene 328, 113-120. doi: 10.1016/j.gene.2003.11.019.
    • (2004) Gene , vol.328 , pp. 113-120
    • Mackenzie, N.C.1    Brito, M.2    Reyes, A.E.3    Allende, M.L.4
  • 83
    • 57149103308 scopus 로고    scopus 로고
    • Zebrafish mutants calamity and catastrophe define critical pathways of gene-nutrient interactions in developmental copper metabolism
    • doi: 10.1371/journal.pgen.1000261
    • Madsen, E. C., and Gitlin, J. D. (2008). Zebrafish mutants calamity and catastrophe define critical pathways of gene-nutrient interactions in developmental copper metabolism. PLoS Genet 4:e1000261. doi: 10.1371/journal.pgen.1000261.
    • (2008) PLoS Genet , vol.4
    • Madsen, E.C.1    Gitlin, J.D.2
  • 84
    • 41649088875 scopus 로고    scopus 로고
    • In vivo correction of a Menkes disease model using antisense oligonucleotides
    • doi: 10.1073/pnas.0710865105
    • Madsen, E. C., Morcos, P. A., Mendelsohn, B. A., and Gitlin, J. D. (2008). In vivo correction of a Menkes disease model using antisense oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 105, 3909-3914. doi: 10.1073/pnas.0710865105.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3909-3914
    • Madsen, E.C.1    Morcos, P.A.2    Mendelsohn, B.A.3    Gitlin, J.D.4
  • 85
    • 0033861745 scopus 로고    scopus 로고
    • A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
    • doi: 10.1016/S1097-2765(00)80425-6
    • McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., et al. (2000). A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol. Cell 5, 299-309. doi: 10.1016/S1097-2765(00)80425-6.
    • (2000) Mol. Cell , vol.5 , pp. 299-309
    • McKie, A.T.1    Marciani, P.2    Rolfs, A.3    Brennan, K.4    Wehr, K.5    Barrow, D.6
  • 86
    • 84875627900 scopus 로고    scopus 로고
    • Selenium in the environment, metabolism and involvement in body functions
    • doi: 10.3390/molecules18033292
    • Mehdi, Y., Hornick, J. L., Istasse, L., and Dufrasne, I. (2013). Selenium in the environment, metabolism and involvement in body functions. Molecules 18, 3292-3311. doi: 10.3390/molecules18033292.
    • (2013) Molecules , vol.18 , pp. 3292-3311
    • Mehdi, Y.1    Hornick, J.L.2    Istasse, L.3    Dufrasne, I.4
  • 87
    • 33746558633 scopus 로고    scopus 로고
    • Atp7a determines a hierarchy of copper metabolism essential for notochord development
    • doi: 10.1016/j.cmet.2006.05.001
    • Mendelsohn, B. A., Yin, C., Johnson, S. L., Wilm, T. P., Solnica-Krezel, L., and Gitlin, J. D. (2006). Atp7a determines a hierarchy of copper metabolism essential for notochord development. Cell Metab. 4, 155-162. doi: 10.1016/j.cmet.2006.05.001.
    • (2006) Cell Metab. , vol.4 , pp. 155-162
    • Mendelsohn, B.A.1    Yin, C.2    Johnson, S.L.3    Wilm, T.P.4    Solnica-Krezel, L.5    Gitlin, J.D.6
  • 88
    • 12844260664 scopus 로고    scopus 로고
    • Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload
    • doi: 10.1182/blood-2004-07-2966
    • Mims, M. P., Guan, Y., Pospisilova, D., Priwitzerova, M., Indrak, K., Ponka, P., et al. (2005). Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload. Blood 105, 1337-1342. doi: 10.1182/blood-2004-07-2966.
    • (2005) Blood , vol.105 , pp. 1337-1342
    • Mims, M.P.1    Guan, Y.2    Pospisilova, D.3    Priwitzerova, M.4    Indrak, K.5    Ponka, P.6
  • 89
    • 0038736811 scopus 로고    scopus 로고
    • The d subunit of the vacuolar ATPase (Atp6d) is essential for embryonic development
    • doi: 10.1023/A:1022118627058
    • Miura, G. I., Froelick, G. J., Marsh, D. J., Stark, K. L., and Palmiter, R. D. (2003). The d subunit of the vacuolar ATPase (Atp6d) is essential for embryonic development. Transgenic. Res. 12, 131-133. doi: 10.1023/A:1022118627058.
    • (2003) Transgenic. Res. , vol.12 , pp. 131-133
    • Miura, G.I.1    Froelick, G.J.2    Marsh, D.J.3    Stark, K.L.4    Palmiter, R.D.5
  • 90
    • 17944380796 scopus 로고    scopus 로고
    • Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
    • doi: 10.1172/JCI13468
    • Montosi, G., Donovan, A., Totaro, A., Garuti, C., Pignatti, E., Cassanelli, S., et al. (2001). Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J. Clin. Invest. 108, 619-623. doi: 10.1172/JCI13468.
    • (2001) J. Clin. Invest. , vol.108 , pp. 619-623
    • Montosi, G.1    Donovan, A.2    Totaro, A.3    Garuti, C.4    Pignatti, E.5    Cassanelli, S.6
  • 91
    • 84897952168 scopus 로고    scopus 로고
    • 'Cellular Iron Physiology'
    • eds G. J. Anderson and G. D. McLaren. (New York, NY: Humana Press). doi: 10.1007/978-1-60327-485-2_2.
    • Muckenthaler, M. U., and Lill, R. (2012). "Cellular Iron Physiology," in Iron Physiology and Pathophysiology in Humans, eds G. J. Anderson and G. D. McLaren. (New York, NY: Humana Press), 27-50. doi: 10.1007/978-1-60327-485-2_2.
    • (2012) Iron Physiology and Pathophysiology in Humans , pp. 27-50
    • Muckenthaler, M.U.1    Lill, R.2
  • 92
    • 17044451174 scopus 로고    scopus 로고
    • A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions
    • doi: 10.1074/jbc.M307847200
    • Muhlenhoff, U., Stadler, J. A., Richhardt, N., Seubert, A., Eickhorst, T., Schweyen, R. J., et al. (2003). A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions. J. Biol. Chem. 278, 40612-40620. doi: 10.1074/jbc.M307847200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40612-40620
    • Muhlenhoff, U.1    Stadler, J.A.2    Richhardt, N.3    Seubert, A.4    Eickhorst, T.5    Schweyen, R.J.6
  • 93
    • 84861525631 scopus 로고    scopus 로고
    • Deletion of TMPRSS6 attenuates the phenotype in a mouse model of beta-thalassemia
    • doi: 10.1182/blood-2012-01-401885
    • Nai, A., Pagani, A., Mandelli, G., Lidonnici, M. R., Silvestri, L., Ferrari, G., et al. (2012). Deletion of TMPRSS6 attenuates the phenotype in a mouse model of beta-thalassemia. Blood 119, 5021-5029. doi: 10.1182/blood-2012-01-401885.
    • (2012) Blood , vol.119 , pp. 5021-5029
    • Nai, A.1    Pagani, A.2    Mandelli, G.3    Lidonnici, M.R.4    Silvestri, L.5    Ferrari, G.6
  • 94
    • 77956276207 scopus 로고    scopus 로고
    • Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice
    • doi: 10.1182/blood-2010-04-278655
    • Nai, A., Pagani, A., Silvestri, L., and Camaschella, C. (2010). Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice. Blood 116, 851-852. doi: 10.1182/blood-2010-04-278655.
    • (2010) Blood , vol.116 , pp. 851-852
    • Nai, A.1    Pagani, A.2    Silvestri, L.3    Camaschella, C.4
  • 95
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • doi: 10.1126/science.1104742
    • Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., et al. (2004). Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306, 2090-2093. doi: 10.1126/science.1104742.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6
  • 96
    • 34548348802 scopus 로고    scopus 로고
    • Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease
    • doi: 10.1016/j.nbd.2007.05.004
    • Niciu, M. J., Ma, X. M., El Meskini, R., Pachter, J. S., Mains, R. E., and Eipper, B. A. (2007). Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease. Neurobiol. Dis. 27, 278-291. doi: 10.1016/j.nbd.2007.05.004.
    • (2007) Neurobiol. Dis. , vol.27 , pp. 278-291
    • Niciu, M.J.1    Ma, X.M.2    El Meskini, R.3    Pachter, J.S.4    Mains, R.E.5    Eipper, B.A.6
  • 97
    • 70349113136 scopus 로고    scopus 로고
    • Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants
    • doi: 10.2337/db09-0551
    • Nicolson, T. J., Bellomo, E. A., Wijesekara, N., Loder, M. K., Baldwin, J. M., Gyulkhandanyan, A. V., et al. (2009). Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes 58, 2070-2083. doi: 10.2337/db09-0551.
    • (2009) Diabetes , vol.58 , pp. 2070-2083
    • Nicolson, T.J.1    Bellomo, E.A.2    Wijesekara, N.3    Loder, M.K.4    Baldwin, J.M.5    Gyulkhandanyan, A.V.6
  • 98
    • 23644444316 scopus 로고    scopus 로고
    • Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
    • doi: 10.1172/JCI25683
    • Niederkofler, V., Salie, R., and Arber, S. (2005). Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J. Clin. Invest. 115, 2180-2186. doi: 10.1172/JCI25683.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2180-2186
    • Niederkofler, V.1    Salie, R.2    Arber, S.3
  • 99
    • 0034930197 scopus 로고    scopus 로고
    • A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
    • doi: 10.1038/90038
    • Njajou, O. T., Vaessen, N., Joosse, M., Berghuis, B., Van Dongen, J. W., Breuning, M. H., et al. (2001). A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat. Genet. 28, 213-214. doi: 10.1038/90038.
    • (2001) Nat. Genet. , vol.28 , pp. 213-214
    • Njajou, O.T.1    Vaessen, N.2    Joosse, M.3    Berghuis, B.4    Van Dongen, J.W.5    Breuning, M.H.6
  • 100
    • 33747849534 scopus 로고    scopus 로고
    • Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function
    • doi: 10.1016/j.cmet.2006.08.009
    • Nose, Y., Kim, B. E., and Thiele, D. J. (2006). Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab. 4, 235-244. doi: 10.1016/j.cmet.2006.08.009.
    • (2006) Cell Metab. , vol.4 , pp. 235-244
    • Nose, Y.1    Kim, B.E.2    Thiele, D.J.3
  • 101
    • 27644455133 scopus 로고    scopus 로고
    • Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
    • doi: 10.1038/ng1658
    • Ohgami, R. S., Campagna, D. R., Greer, E. L., Antiochos, B., McDonald, A., Chen, J., et al. (2005). Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat. Genet. 37, 1264-1269. doi: 10.1038/ng1658.
    • (2005) Nat. Genet. , vol.37 , pp. 1264-1269
    • Ohgami, R.S.1    Campagna, D.R.2    Greer, E.L.3    Antiochos, B.4    McDonald, A.5    Chen, J.6
  • 102
    • 59449083869 scopus 로고    scopus 로고
    • Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2
    • doi: 10.1128/MCB.01685-08
    • Paradkar, P. N., Zumbrennen, K. B., Paw, B. H., Ward, D. M., and Kaplan, J. (2009). Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2. Mol. Cell. Biol. 29, 1007-1016. doi: 10.1128/MCB.01685-08.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1007-1016
    • Paradkar, P.N.1    Zumbrennen, K.B.2    Paw, B.H.3    Ward, D.M.4    Kaplan, J.5
  • 103
    • 0037477740 scopus 로고    scopus 로고
    • A delicate balance: homeostatic control of copper uptake and distribution
    • Pena, M. M., Lee, J., and Thiele, D. J. (1999). A delicate balance: homeostatic control of copper uptake and distribution. J. Nutr. 129, 1251-1260.
    • (1999) J. Nutr. , vol.129 , pp. 1251-1260
    • Pena, M.M.1    Lee, J.2    Thiele, D.J.3
  • 104
    • 34347328067 scopus 로고    scopus 로고
    • Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron, and calcium homeostasis
    • doi: 10.1002/dvg.20297
    • Peters, J. L., Dufner-Beattie, J., Xu, W., Geiser, J., Lahner, B., Salt, D. E., et al. (2007). Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron, and calcium homeostasis. Genesis 45, 339-352. doi: 10.1002/dvg.20297.
    • (2007) Genesis , vol.45 , pp. 339-352
    • Peters, J.L.1    Dufner-Beattie, J.2    Xu, W.3    Geiser, J.4    Lahner, B.5    Salt, D.E.6
  • 105
    • 0742272103 scopus 로고    scopus 로고
    • The ferroportin disease
    • doi: 10.1016/j.bcmd.2003.08.003
    • Pietrangelo, A. (2004). The ferroportin disease. Blood Cells Mol. Dis. 32, 131-138. doi: 10.1016/j.bcmd.2003.08.003.
    • (2004) Blood Cells Mol. Dis. , vol.32 , pp. 131-138
    • Pietrangelo, A.1
  • 106
    • 70249130817 scopus 로고    scopus 로고
    • Thyroid gland development and function in the zebrafish model
    • doi: 10.1016/j.mce.2009.05.011
    • Porazzi, P., Calebiro, D., Benato, F., Tiso, N., and Persani, L. (2009). Thyroid gland development and function in the zebrafish model. Mol. Cell Endocrinol. 312, 14-23. doi: 10.1016/j.mce.2009.05.011.
    • (2009) Mol. Cell Endocrinol. , vol.312 , pp. 14-23
    • Porazzi, P.1    Calebiro, D.2    Benato, F.3    Tiso, N.4    Persani, L.5
  • 107
    • 18244431887 scopus 로고    scopus 로고
    • Vertebrate genome evolution and the zebrafish gene map
    • doi: 10.1038/ng0498-345
    • Postlethwait, J. H., Yan, Y. L., Gates, M. A., Horne, S., Amores, A., Brownlie, A., et al. (1998). Vertebrate genome evolution and the zebrafish gene map. Nat. Genet. 18, 345-349. doi: 10.1038/ng0498-345.
    • (1998) Nat. Genet. , vol.18 , pp. 345-349
    • Postlethwait, J.H.1    Yan, Y.L.2    Gates, M.A.3    Horne, S.4    Amores, A.5    Brownlie, A.6
  • 108
    • 69249226366 scopus 로고    scopus 로고
    • Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion
    • doi: 10.1042/BJ20090530
    • Pound, L. D., Sarkar, S. A., Benninger, R. K., Wang, Y., Suwanichkul, A., Shadoan, M. K., et al. (2009). Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. Biochem. J. 421, 371-376. doi: 10.1042/BJ20090530.
    • (2009) Biochem. J. , vol.421 , pp. 371-376
    • Pound, L.D.1    Sarkar, S.A.2    Benninger, R.K.3    Wang, Y.4    Suwanichkul, A.5    Shadoan, M.K.6
  • 110
    • 84862537820 scopus 로고    scopus 로고
    • Discovery of human zinc deficiency: 50 years later
    • doi: 10.1016/j.jtemb.2012.04.004
    • Prasad, A. S. (2012). Discovery of human zinc deficiency: 50 years later. J. Trace Elem. Med. Biol. 26, 66-69. doi: 10.1016/j.jtemb.2012.04.004.
    • (2012) J. Trace Elem. Med. Biol. , vol.26 , pp. 66-69
    • Prasad, A.S.1
  • 111
    • 25844497061 scopus 로고    scopus 로고
    • Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells
    • doi: 10.1042/BJ20050568
    • Qiu, A., and Hogstrand, C. (2005). Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells. Biochem. J. 390, 777-786. doi: 10.1042/BJ20050568.
    • (2005) Biochem. J. , vol.390 , pp. 777-786
    • Qiu, A.1    Hogstrand, C.2
  • 112
    • 21744432348 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio)
    • doi: 10.1042/BJ20041807
    • Qiu, A., Shayeghi, M., and Hogstrand, C. (2005). Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio). Biochem. J. 388, 745-754. doi: 10.1042/BJ20041807.
    • (2005) Biochem. J. , vol.388 , pp. 745-754
    • Qiu, A.1    Shayeghi, M.2    Hogstrand, C.3
  • 113
    • 12644292903 scopus 로고    scopus 로고
    • Characterization of zebrafish mutants with defects in embryonic hematopoiesis
    • Ransom, D. G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R. N., et al. (1996). Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development 123, 311-319.
    • (1996) Development , vol.123 , pp. 311-319
    • Ransom, D.G.1    Haffter, P.2    Odenthal, J.3    Brownlie, A.4    Vogelsang, E.5    Kelsh, R.N.6
  • 114
    • 0035894377 scopus 로고    scopus 로고
    • How the zebrafish gets its stripes
    • doi: 10.1006/dbio.2001.0418
    • Rawls, J. F., Mellgren, E. M., and Johnson, S. L. (2001). How the zebrafish gets its stripes. Dev. Biol. 240, 301-314. doi: 10.1006/dbio.2001.0418.
    • (2001) Dev. Biol. , vol.240 , pp. 301-314
    • Rawls, J.F.1    Mellgren, E.M.2    Johnson, S.L.3
  • 115
    • 84864413232 scopus 로고    scopus 로고
    • Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family
    • doi: 10.1371/journal.pone.0042249
    • Rodrigues, J. R., Fernandez, A., Canales, J., Cabezas, A., Ribeiro, J. M., Costas, M. J., and Cameselle, J. C. (2012). Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family. PLoS ONE 7:e42249. doi: 10.1371/journal.pone.0042249.
    • (2012) PLoS ONE , vol.7
    • Rodrigues, J.R.1    Fernandez, A.2    Canales, J.3    Cabezas, A.4    Ribeiro, J.M.5    Costas, M.J.6    Cameselle, J.C.7
  • 116
    • 0036226063 scopus 로고    scopus 로고
    • Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes
    • doi: 10.1091/mbc.01-10-0517
    • Rodriguez-Manzaneque, M. T., Tamarit, J., Belli, G., Ros, J., and Herrero, E. (2002). Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol. Biol. Cell 13, 1109-1121. doi: 10.1091/mbc.01-10-0517.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1109-1121
    • Rodriguez-Manzaneque, M.T.1    Tamarit, J.2    Belli, G.3    Ros, J.4    Herrero, E.5
  • 117
    • 77951442893 scopus 로고    scopus 로고
    • Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues
    • doi: 10.1182/blood-2009-09-240960
    • Roetto, A., Di Cunto, F., Pellegrino, R. M., Hirsch, E., Azzolino, O., Bondi, A., et al. (2010). Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues. Blood 115, 3382-3389. doi: 10.1182/blood-2009-09-240960.
    • (2010) Blood , vol.115 , pp. 3382-3389
    • Roetto, A.1    Di Cunto, F.2    Pellegrino, R.M.3    Hirsch, E.4    Azzolino, O.5    Bondi, A.6
  • 119
    • 0033198793 scopus 로고    scopus 로고
    • Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
    • doi: 10.1093/emboj/18.17.4657
    • Sano, S., Itami, S., Takeda, K., Tarutani, M., Yamaguchi, Y., Miura, H., et al. (1999). Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J. 18, 4657-4668. doi: 10.1093/emboj/18.17.4657.
    • (1999) EMBO J. , vol.18 , pp. 4657-4668
    • Sano, S.1    Itami, S.2    Takeda, K.3    Tarutani, M.4    Yamaguchi, Y.5    Miura, H.6
  • 120
    • 20844462571 scopus 로고    scopus 로고
    • In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations
    • doi: 10.1182/blood-2004-11-4502
    • Schimanski, L. M., Drakesmith, H., Merryweather-Clarke, A. T., Viprakasit, V., Edwards, J. P., Sweetland, E., et al. (2005). In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations. Blood 105, 4096-4102. doi: 10.1182/blood-2004-11-4502.
    • (2005) Blood , vol.105 , pp. 4096-4102
    • Schimanski, L.M.1    Drakesmith, H.2    Merryweather-Clarke, A.T.3    Viprakasit, V.4    Edwards, J.P.5    Sweetland, E.6
  • 121
    • 33749534285 scopus 로고    scopus 로고
    • Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity
    • doi: 10.1073/pnas.0605390103
    • Schlief, M. L., West, T., Craig, A. M., Holtzman, D. M., and Gitlin, J. D. (2006). Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc. Natl. Acad. Sci. U.S.A. 103, 14919-14924. doi: 10.1073/pnas.0605390103.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 14919-14924
    • Schlief, M.L.1    West, T.2    Craig, A.M.3    Holtzman, D.M.4    Gitlin, J.D.5
  • 122
    • 80855133515 scopus 로고    scopus 로고
    • Silencing of RhoA nucleotide exchange factor, ARHGEF3, reveals its unexpected role in iron uptake
    • doi: 10.1182/blood-2011-02-337295
    • Serbanovic-Canic, J., Cvejic, A., Soranzo, N., Stemple, D. L., Ouwehand, W. H., and Freson, K. (2011). Silencing of RhoA nucleotide exchange factor, ARHGEF3, reveals its unexpected role in iron uptake. Blood 118, 4967-4976. doi: 10.1182/blood-2011-02-337295.
    • (2011) Blood , vol.118 , pp. 4967-4976
    • Serbanovic-Canic, J.1    Cvejic, A.2    Soranzo, N.3    Stemple, D.L.4    Ouwehand, W.H.5    Freson, K.6
  • 123
    • 33644748145 scopus 로고    scopus 로고
    • Mitoferrin is essential for erythroid iron assimilation
    • doi: 10.1038/nature04512
    • Shaw, G. C., Cope, J. J., Li, L., Corson, K., Hersey, C., Ackermann, G. E., et al. (2006). Mitoferrin is essential for erythroid iron assimilation. Nature 440, 96-100. doi: 10.1038/nature04512.
    • (2006) Nature , vol.440 , pp. 96-100
    • Shaw, G.C.1    Cope, J.J.2    Li, L.3    Corson, K.4    Hersey, C.5    Ackermann, G.E.6
  • 124
    • 70350644759 scopus 로고    scopus 로고
    • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
    • doi: 10.1038/ng.467
    • Soranzo, N., Spector, T. D., Mangino, M., Kuhnel, B., Rendon, A., Teumer, A., et al. (2009). A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat. Genet. 41, 1182-1190. doi: 10.1038/ng.467.
    • (2009) Nat. Genet. , vol.41 , pp. 1182-1190
    • Soranzo, N.1    Spector, T.D.2    Mangino, M.3    Kuhnel, B.4    Rendon, A.5    Teumer, A.6
  • 125
    • 84897929383 scopus 로고    scopus 로고
    • 'Proteins of iron homeostasis'
    • eds. G. J. Anderson and G. D. McLaren. (New York, NY: Humana Press)
    • Srai, S. K., and Sharp, P. (2012). "Proteins of iron homeostasis," in Iron Physiology and Pathophysiology in Humans, eds G. J. Anderson and G. D. McLaren. (New York, NY: Humana Press), 3-25.
    • (2012) Iron Physiology and Pathophysiology in Humans , pp. 3-25
    • Srai, S.K.1    Sharp, P.2
  • 126
    • 29344433505 scopus 로고    scopus 로고
    • Zinc: a multipurpose trace element
    • doi: 10.1007/s00204-005-0009-5
    • Stefanidou, M., Maravelias, C., Dona, A., and Spiliopoulou, C. (2006). Zinc: a multipurpose trace element. Arch. Toxicol. 80, 1-9. doi: 10.1007/s00204-005-0009-5.
    • (2006) Arch. Toxicol. , vol.80 , pp. 1-9
    • Stefanidou, M.1    Maravelias, C.2    Dona, A.3    Spiliopoulou, C.4
  • 127
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • doi: 10.1016/0891-5849(94)00159-H
    • Stohs, S. J., and Bagchi, D. (1995). Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med. 18, 321-336. doi: 10.1016/0891-5849(94)00159-H.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 128
    • 0036838080 scopus 로고    scopus 로고
    • Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development
    • doi: 10.1128/MCB.22.21.7614-7621.2002
    • Takahashi, Y., Kako, K., Kashiwabara, S., Takehara, A., Inada, Y., Arai, H., et al. (2002). Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development. Mol. Cell Biol. 22, 7614-7621. doi: 10.1128/MCB.22.21.7614-7621.2002.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7614-7621
    • Takahashi, Y.1    Kako, K.2    Kashiwabara, S.3    Takehara, A.4    Inada, Y.5    Arai, H.6
  • 129
    • 0033931310 scopus 로고    scopus 로고
    • LIV-1 breast cancer protein belongs to new family of histidine-rich membrane proteins with potential to control intracellular Zn2+ homeostasis
    • doi: 10.1080/15216540050033087
    • Taylor, K. M. (2000). LIV-1 breast cancer protein belongs to new family of histidine-rich membrane proteins with potential to control intracellular Zn2+ homeostasis. IUBMB Life 49, 249-253. doi: 10.1080/15216540050033087.
    • (2000) IUBMB Life , vol.49 , pp. 249-253
    • Taylor, K.M.1
  • 130
    • 0042197349 scopus 로고    scopus 로고
    • Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish
    • doi: 10.1016/S1567-133X(03)00054-1
    • Thisse, C., Degrave, A., Kryukov, G. V., Gladyshev, V. N., Obrecht-Pflumio, S., Krol, A., et al. (2003). Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish. Gene Exp. Pattern 3, 525-532. doi: 10.1016/S1567-133X(03)00054-1.
    • (2003) Gene Exp. Pattern , vol.3 , pp. 525-532
    • Thisse, C.1    Degrave, A.2    Kryukov, G.V.3    Gladyshev, V.N.4    Obrecht-Pflumio, S.5    Krol, A.6
  • 131
    • 79956321032 scopus 로고    scopus 로고
    • Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria
    • doi: 10.1182/blood-2010-11-319483
    • Troadec, M. B., Warner, D., Wallace, J., Thomas, K., Spangrude, G. J., Phillips, J., et al. (2011). Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria. Blood 117, 5494-5502. doi: 10.1182/blood-2010-11-319483.
    • (2011) Blood , vol.117 , pp. 5494-5502
    • Troadec, M.B.1    Warner, D.2    Wallace, J.3    Thomas, K.4    Spangrude, G.J.5    Phillips, J.6
  • 132
    • 0034507642 scopus 로고    scopus 로고
    • Expression and characterization of nonmammalian selenoprotein P in the zebrafish, Danio rerio
    • doi: 10.1046/j.1365-2443.2000.00375.x
    • Tujebajeva, R. M., Ransom, D. G., Harney, J. W., and Berry, M. J. (2000). Expression and characterization of nonmammalian selenoprotein P in the zebrafish, Danio rerio. Genes Cells 5, 897-903. doi: 10.1046/j.1365-2443.2000.00375.x.
    • (2000) Genes Cells , vol.5 , pp. 897-903
    • Tujebajeva, R.M.1    Ransom, D.G.2    Harney, J.W.3    Berry, M.J.4
  • 133
    • 77951622872 scopus 로고    scopus 로고
    • Menkes disease
    • doi: 10.1038/ejhg.2009.187
    • Tumer, Z., and Moller, L. B. (2010). Menkes disease. Eur. J. Hum. Genet. 18, 511-518. doi: 10.1038/ejhg.2009.187.
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 511-518
    • Tumer, Z.1    Moller, L.B.2
  • 134
    • 0038406726 scopus 로고    scopus 로고
    • Metallothioneins: new functional and structural insights
    • doi: 10.1016/S1367-5931(00)00082-X
    • Vasak, M., and Hasler, D. W. (2000). Metallothioneins: new functional and structural insights. Curr. Opin. Chem. Biol. 4, 177-183. doi: 10.1016/S1367-5931(00)00082-X.
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 177-183
    • Vasak, M.1    Hasler, D.W.2
  • 135
    • 38649128515 scopus 로고    scopus 로고
    • Hfe acts in hepatocytes to prevent hemochromatosis
    • doi: 10.1016/j.cmet.2007.11.014
    • Vujic Spasic, M., Kiss, J., Herrmann, T., Galy, B., Martinache, S., Stolte, J., et al. (2008). Hfe acts in hepatocytes to prevent hemochromatosis. Cell Metab 7, 173-178. doi: 10.1016/j.cmet.2007.11.014.
    • (2008) Cell Metab , vol.7 , pp. 173-178
    • Vujic Spasic, M.1    Kiss, J.2    Herrmann, T.3    Galy, B.4    Martinache, S.5    Stolte, J.6
  • 136
    • 34248374866 scopus 로고    scopus 로고
    • Physiologic systemic iron metabolism in mice deficient for duodenal Hfe
    • doi: 10.1182/blood-2006-07-036186
    • Vujic Spasic, M., Kiss, J., Herrmann, T., Kessler, R., Stolte, J., Galy, B., et al. (2007). Physiologic systemic iron metabolism in mice deficient for duodenal Hfe. Blood 109, 4511-4517. doi: 10.1182/blood-2006-07-036186.
    • (2007) Blood , vol.109 , pp. 4511-4517
    • Vujic Spasic, M.1    Kiss, J.2    Herrmann, T.3    Kessler, R.4    Stolte, J.5    Galy, B.6
  • 137
    • 0032909207 scopus 로고    scopus 로고
    • Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
    • doi: 10.1038/5979
    • Vulpe, C. D., Kuo, Y. M., Murphy, T. L., Cowley, L., Askwith, C., Libina, N., et al. (1999). Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat. Genet. 21, 195-199. doi: 10.1038/5979.
    • (1999) Nat. Genet. , vol.21 , pp. 195-199
    • Vulpe, C.D.1    Kuo, Y.M.2    Murphy, T.L.3    Cowley, L.4    Askwith, C.5    Libina, N.6
  • 139
    • 0035029769 scopus 로고    scopus 로고
    • The influence of zinc on apical uptake of cadmium in the gills and cadmium influx to the circulatory system in zebrafish (Danio rerio)
    • doi: 10.1016/S1532-0456(00)00188-5
    • Wicklund Glynn, A. (2001). The influence of zinc on apical uptake of cadmium in the gills and cadmium influx to the circulatory system in zebrafish (Danio rerio). Comp. Biochem. Physiol. C Toxicol. Pharmacol. 128, 165-172. doi: 10.1016/S1532-0456(00)00188-5.
    • (2001) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.128 , pp. 165-172
    • Wicklund Glynn, A.1
  • 140
    • 26944485546 scopus 로고    scopus 로고
    • Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione
    • doi: 10.1093/nar/gki881
    • Wimmer, U., Wang, Y., Georgiev, O., and Schaffner, W. (2005). Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res. 33, 5715-5727. doi: 10.1093/nar/gki881.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 5715-5727
    • Wimmer, U.1    Wang, Y.2    Georgiev, O.3    Schaffner, W.4
  • 141
    • 19944426386 scopus 로고    scopus 로고
    • The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1
    • doi: 10.1242/dev.01540
    • Wingert, R. A., Brownlie, A., Galloway, J. L., Dooley, K., Fraenkel, P., Axe, J. L., et al. (2004). The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development 131, 6225-6235. doi: 10.1242/dev.01540.
    • (2004) Development , vol.131 , pp. 6225-6235
    • Wingert, R.A.1    Brownlie, A.2    Galloway, J.L.3    Dooley, K.4    Fraenkel, P.5    Axe, J.L.6
  • 142
    • 23944500052 scopus 로고    scopus 로고
    • Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
    • doi: 10.1038/nature03887
    • Wingert, R. A., Galloway, J. L., Barut, B., Foott, H., Fraenkel, P., Axe, J. L., et al. (2005). Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature 436, 1035-1039. doi: 10.1038/nature03887.
    • (2005) Nature , vol.436 , pp. 1035-1039
    • Wingert, R.A.1    Galloway, J.L.2    Barut, B.3    Foott, H.4    Fraenkel, P.5    Axe, J.L.6
  • 143
    • 0034646410 scopus 로고    scopus 로고
    • Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase
    • doi: 10.1073/pnas.040461197
    • Wong, P. C., Waggoner, D., Subramaniam, J. R., Tessarollo, L., Bartnikas, T. B., Culotta, V. C., et al. (2000). Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 97, 2886-2891. doi: 10.1073/pnas.040461197.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 2886-2891
    • Wong, P.C.1    Waggoner, D.2    Subramaniam, J.R.3    Tessarollo, L.4    Bartnikas, T.B.5    Culotta, V.C.6
  • 144
    • 0032987643 scopus 로고    scopus 로고
    • The zebrafish genome contains two distinct selenocysteine tRNA[Ser]sec genes
    • Xu, X. M., Zhou, X., Carlson, B. A., Kim, L. K., Huh, T. L., Lee, B. J., et al. (1999). The zebrafish genome contains two distinct selenocysteine tRNA[Ser]sec genes. FEBS Lett. 454, 16-20.
    • (1999) FEBS Lett. , vol.454 , pp. 16-20
    • Xu, X.M.1    Zhou, X.2    Carlson, B.A.3    Kim, L.K.4    Huh, T.L.5    Lee, B.J.6
  • 145
    • 0036199628 scopus 로고    scopus 로고
    • Stat3 controls cell movements during zebrafish gastrulation
    • doi: 10.1016/S1534-5807(02)00126-0
    • Yamashita, S., Miyagi, C., Carmany-Rampey, A., Shimizu, T., Fujii, R., Schier, A. F., et al. (2002). Stat3 controls cell movements during zebrafish gastrulation. Dev. Cell 2, 363-375. doi: 10.1016/S1534-5807(02)00126-0.
    • (2002) Dev. Cell , vol.2 , pp. 363-375
    • Yamashita, S.1    Miyagi, C.2    Carmany-Rampey, A.3    Shimizu, T.4    Fujii, R.5    Schier, A.F.6
  • 146
    • 2442674220 scopus 로고    scopus 로고
    • Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
    • doi: 10.1038/nature02545
    • Yamashita, S., Miyagi, C., Fukada, T., Kagara, N., Che, Y. S., and Hirano, T. (2004). Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer. Nature 429, 298-302. doi: 10.1038/nature02545.
    • (2004) Nature , vol.429 , pp. 298-302
    • Yamashita, S.1    Miyagi, C.2    Fukada, T.3    Kagara, N.4    Che, Y.S.5    Hirano, T.6
  • 147
    • 84865057527 scopus 로고    scopus 로고
    • Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish
    • doi: 10.1371/journal.pone.0042939
    • Yan, G., Zhang, Y., Yu, J., Yu, Y., Zhang, F., Zhang, Z., et al. (2012). Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish. PLoS ONE 7:e42939. doi: 10.1371/journal.pone.0042939.
    • (2012) PLoS ONE , vol.7
    • Yan, G.1    Zhang, Y.2    Yu, J.3    Yu, Y.4    Zhang, F.5    Zhang, Z.6
  • 148
    • 18744397511 scopus 로고    scopus 로고
    • An iron delivery pathway mediated by a lipocalin
    • doi: 10.1016/S1097-2765(02)00710-4
    • Yang, J., Goetz, D., Li, J. Y., Wang, W., Mori, K., Setlik, D., et al. (2002). An iron delivery pathway mediated by a lipocalin. Mol. Cell 10, 1045-1056. doi: 10.1016/S1097-2765(02)00710-4.
    • (2002) Mol. Cell , vol.10 , pp. 1045-1056
    • Yang, J.1    Goetz, D.2    Li, J.Y.3    Wang, W.4    Mori, K.5    Setlik, D.6
  • 149
    • 80051895753 scopus 로고    scopus 로고
    • Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses
    • doi: 10.1182/blood-2011-01-330324
    • Zhang, Z., Zhang, F., An, P., Guo, X., Shen, Y., Tao, Y., et al. (2011). Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood 118, 1912-1922. doi: 10.1182/blood-2011-01-330324.
    • (2011) Blood , vol.118 , pp. 1912-1922
    • Zhang, Z.1    Zhang, F.2    An, P.3    Guo, X.4    Shen, Y.5    Tao, Y.6
  • 150
    • 84865565820 scopus 로고    scopus 로고
    • Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice
    • doi: 10.1002/hep.25746
    • Zhang, Z., Zhang, F., Guo, X., An, P., Tao, Y., and Wang, F. (2012). Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice. Hepatology 56, 961-971. doi: 10.1002/hep.25746.
    • (2012) Hepatology , vol.56 , pp. 961-971
    • Zhang, Z.1    Zhang, F.2    Guo, X.3    An, P.4    Tao, Y.5    Wang, F.6
  • 151
    • 49049109504 scopus 로고    scopus 로고
    • Regulation of ZIP and ZnT zinc transporters in zebrafish gill: zinc repression of ZIP10 transcription by an intronic MRE cluster
    • doi: 10.1152/physiolgenomics.90206.2008
    • Zheng, D., Feeney, G. P., Kille, P., and Hogstrand, C. (2008). Regulation of ZIP and ZnT zinc transporters in zebrafish gill: zinc repression of ZIP10 transcription by an intronic MRE cluster. Physiol. Genomics 34, 205-214. doi: 10.1152/physiolgenomics.90206.2008.
    • (2008) Physiol. Genomics , vol.34 , pp. 205-214
    • Zheng, D.1    Feeney, G.P.2    Kille, P.3    Hogstrand, C.4
  • 152
    • 77957566159 scopus 로고    scopus 로고
    • Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion
    • doi: 10.1186/1471-2164-11-548
    • Zheng, D., Kille, P., Feeney, G. P., Cunningham, P., Handy, R. D., and Hogstrand, C. (2010a). Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion. BMC Genomics 11:548. doi: 10.1186/1471-2164-11-548.
    • (2010) BMC Genomics , vol.11 , pp. 548
    • Zheng, D.1    Kille, P.2    Feeney, G.P.3    Cunningham, P.4    Handy, R.D.5    Hogstrand, C.6
  • 153
    • 77957566159 scopus 로고    scopus 로고
    • Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation
    • doi: 10.1186/1471-2164-11-553
    • Zheng, D., Kille, P., Feeney, G. P., Cunningham, P., Handy, R. D., and Hogstrand, C. (2010b). Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation. BMC Genomics 11:553. doi: 10.1186/1471-2164-11-553.
    • (2010) BMC Genomics , vol.11 , pp. 553
    • Zheng, D.1    Kille, P.2    Feeney, G.P.3    Cunningham, P.4    Handy, R.D.5    Hogstrand, C.6
  • 154
    • 34248343093 scopus 로고    scopus 로고
    • The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease
    • doi: 10.1182/blood-2007-01-066068
    • Zohn, I. E., De Domenico, I., Pollock, A., Ward, D. M., Goodman, J. F., Liang, X., et al. (2007). The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease. Blood 109, 4174-4180. doi: 10.1182/blood-2007-01-066068.
    • (2007) Blood , vol.109 , pp. 4174-4180
    • Zohn, I.E.1    De Domenico, I.2    Pollock, A.3    Ward, D.M.4    Goodman, J.F.5    Liang, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.