-
1
-
-
2042546096
-
Balancing acts: molecular control of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell. 2004;117:285-97.
-
(2004)
Cell.
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
2
-
-
0032477866
-
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci USA. 1998;95:1148-53.
-
(1998)
Proc Natl Acad Sci USA.
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
3
-
-
27644455133
-
Identification of a ferrireductase required for efficient transferrindependent iron uptake in erythroid cells
-
Ohgami RS, Campagna DR, Greer EL, et al. Identification of a ferrireductase required for efficient transferrindependent iron uptake in erythroid cells. Nat Genet. 2005;37:1264-9.
-
(2005)
Nat Genet.
, vol.37
, pp. 1264-1269
-
-
Ohgami, R.S.1
Campagna, D.R.2
Greer, E.L.3
-
4
-
-
27644526967
-
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice
-
Lim JE, Jin O, Bennett C, et al. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat Genet. 2005;37:1270-3.
-
(2005)
Nat Genet.
, vol.37
, pp. 1270-1273
-
-
Lim, J.E.1
Jin, O.2
Bennett, C.3
-
5
-
-
28644444443
-
Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking
-
White RA, Boydston LA, Brookshier TR, et al. Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking. Genomics. 2005;86:668-73.
-
(2005)
Genomics.
, vol.86
, pp. 668-673
-
-
White, R.A.1
Boydston, L.A.2
Brookshier, T.R.3
-
6
-
-
33646104690
-
The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling
-
Zhang AS, Sheftel AD, Ponka P. The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling. Exp Hematol. 2006;34:593-8.
-
(2006)
Exp Hematol.
, vol.34
, pp. 593-598
-
-
Zhang, A.S.1
Sheftel, A.D.2
Ponka, P.3
-
7
-
-
0034254752
-
The molecular defect in hypotransferrinemic mice
-
Trenor 3rd CC, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice. Blood. 2000;96:1113-8.
-
(2000)
Blood.
, vol.96
, pp. 1113-1118
-
-
Trenor I.I.I, C.C.1
Campagna, D.R.2
Sellers, V.M.3
Andrews, N.C.4
Fleming, M.D.5
-
8
-
-
0036800650
-
Rare causes of hereditary iron overload
-
Ponka P. Rare causes of hereditary iron overload. Semin Hematol. 2002;39:249-62.
-
(2002)
Semin Hematol.
, vol.39
, pp. 249-262
-
-
Ponka, P.1
-
9
-
-
0032959574
-
Transferrin receptor is necessary for development of erythrocytes and the nervous system
-
Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999;21:396-9.
-
(1999)
Nat Genet.
, vol.21
, pp. 396-399
-
-
Levy, J.E.1
Jin, O.2
Fujiwara, Y.3
Kuo, F.4
Andrews, N.C.5
-
10
-
-
12844260664
-
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload
-
Mims MP, Guan Y, Pospisilova D, et al. Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload. Blood. 2005;105:1337-42.
-
(2005)
Blood.
, vol.105
, pp. 1337-1342
-
-
Mims, M.P.1
Guan, Y.2
Pospisilova, D.3
-
11
-
-
0037011924
-
Identification of a host protein essential for assembly of immature HIV-1 capsids
-
Zimmerman C, Klein KC, Kiser PK, et al. Identification of a host protein essential for assembly of immature HIV-1 capsids. Nature. 2002;415:88-92.
-
(2002)
Nature.
, vol.415
, pp. 88-92
-
-
Zimmerman, C.1
Klein, K.C.2
Kiser, P.K.3
-
12
-
-
0035940434
-
Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia
-
Kozyraki R, Fyfe J, Verroust PJ, et al. Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia. Proc Natl Acad Sci USA. 2001;98:12491-6.
-
(2001)
Proc Natl Acad Sci USA.
, vol.98
, pp. 12491-12496
-
-
Kozyraki, R.1
Fyfe, J.2
Verroust, P.J.3
-
13
-
-
50949102412
-
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
-
Muckenthaler M, Galy B, Hentze MW. Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr. 2008;28:197-213.
-
(2008)
Annu Rev Nutr.
, vol.28
, pp. 197-213
-
-
Muckenthaler, M.1
Galy, B.2
Hentze, M.W.3
-
14
-
-
23044503950
-
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
-
Cooperman SS, Meyron-Holtz EG, Olivierre-Wilson H, Ghosh MC, McConnell JP, Rouault TA. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood. 2005;106:1084-91.
-
(2005)
Blood.
, vol.106
, pp. 1084-1091
-
-
Cooperman, S.S.1
Meyron-Holtz, E.G.2
Olivierre-Wilson, H.3
Ghosh, M.C.4
McConnell, J.P.5
Rouault, T.A.6
-
15
-
-
27144467097
-
Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)
-
Galy B, Ferring D, Minana B, et al. Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2). Blood. 2005;106:2580-9.
-
(2005)
Blood.
, vol.106
, pp. 2580-2589
-
-
Galy, B.1
Ferring, D.2
Minana, B.3
-
16
-
-
0033597780
-
Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, et al. Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. J Biol Chem. 1999;274:20826-32.
-
(1999)
J Biol Chem.
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
-
17
-
-
10244265904
-
Diferric transferrin regulates transferrin receptor 2 protein stability
-
Johnson MB, Enns CA. Diferric transferrin regulates transferrin receptor 2 protein stability. Blood. 2004;104:4287-93.
-
(2004)
Blood.
, vol.104
, pp. 4287-4293
-
-
Johnson, M.B.1
Enns, C.A.2
-
18
-
-
10244255021
-
Regulation of transferrin receptor 2 protein levels by transferrin
-
Robb A, Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood. 2004;104:4294-9.
-
(2004)
Blood.
, vol.104
, pp. 4294-4299
-
-
Robb, A.1
Wessling-Resnick, M.2
-
19
-
-
34250318957
-
The cytoplasmic domain of transferrin receptor 2 dictates its stability and response to holotransferrin in Hep3B cells
-
Chen J, Enns CA. The cytoplasmic domain of transferrin receptor 2 dictates its stability and response to holotransferrin in Hep3B cells. J Biol Chem. 2007;282:6201-9.
-
(2007)
J Biol Chem.
, vol.282
, pp. 6201-6209
-
-
Chen, J.1
Enns, C.A.2
-
20
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella C, Roetto A, Cali A, et al. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet. 2000;25:14-5.
-
(2000)
Nat Genet.
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Cali, A.3
-
21
-
-
0035843134
-
Identification of the haemoglobin scavenger receptor
-
Kristiansen M, Graversen JH, Jacobsen C, et al. Identification of the haemoglobin scavenger receptor. Nature. 2001;409:198-201.
-
(2001)
Nature.
, vol.409
, pp. 198-201
-
-
Kristiansen, M.1
Graversen, J.H.2
Jacobsen, C.3
-
22
-
-
30144435054
-
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
-
Schaer DJ, Schaer CA, Buehler PW, et al. CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin. Blood. 2006;107:373-80.
-
(2006)
Blood.
, vol.107
, pp. 373-380
-
-
Schaer, D.J.1
Schaer, C.A.2
Buehler, P.W.3
-
23
-
-
0015980699
-
Transfer of heme from ferrihemoglobin and ferrihemoglobin isolated chains to hemopexin
-
Hrkal Z, Vodrazka Z, Kalousek I. Transfer of heme from ferrihemoglobin and ferrihemoglobin isolated chains to hemopexin. Eur J Biochem. 1974;43:73-8.
-
(1974)
Eur J Biochem.
, vol.43
, pp. 73-78
-
-
Hrkal, Z.1
Vodrazka, Z.2
Kalousek, I.3
-
24
-
-
27144551314
-
Identification of the receptor scavenging hemopexin-heme complexes
-
Hvidberg V, Maniecki MB, Jacobsen C, Hojrup P, Moller HJ, Moestrup SK. Identification of the receptor scavenging hemopexin-heme complexes. Blood. 2005;106:2572-9.
-
(2005)
Blood.
, vol.106
, pp. 2572-2579
-
-
Hvidberg, V.1
Maniecki, M.B.2
Jacobsen, C.3
Hojrup, P.4
Moller, H.J.5
Moestrup, S.K.6
-
25
-
-
0033485566
-
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice
-
Tolosano E, Hirsch E, Patrucco E, et al. Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood. 1999;94:3906-14.
-
(1999)
Blood.
, vol.94
, pp. 3906-3914
-
-
Tolosano, E.1
Hirsch, E.2
Patrucco, E.3
-
26
-
-
0036893587
-
Enhanced splenomegaly and severe liver inflammation in haptoglobin/ hemopexin double-null mice after acute hemolysis
-
Tolosano E, Fagoonee S, Hirsch E, et al. Enhanced splenomegaly and severe liver inflammation in haptoglobin/ hemopexin double-null mice after acute hemolysis. Blood. 2002;100:4201-8.
-
(2002)
Blood.
, vol.100
, pp. 4201-4208
-
-
Tolosano, E.1
Fagoonee, S.2
Hirsch, E.3
-
28
-
-
0035793856
-
An iron-regulated ferric reductase associated with the absorption of dietary iron
-
McKie AT, Barrow D, Latunde-Dada GO, et al. An iron-regulated ferric reductase associated with the absorption of dietary iron. Science. 2001;291:1755-9.
-
(2001)
Science.
, vol.291
, pp. 1755-1759
-
-
McKie, A.T.1
Barrow, D.2
Latunde-Dada, G.O.3
-
29
-
-
27144507493
-
Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice
-
Gunshin H, Starr CN, Direnzo C, et al. Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. Blood. 2005;106(8):2879-83.
-
(2005)
Blood.
, vol.106
, Issue.8
, pp. 2879-2883
-
-
Gunshin, H.1
Starr, C.N.2
Direnzo, C.3
-
30
-
-
18244399587
-
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
-
Gunshin H, Fujiwara Y, Custodio AO, Direnzo C, Robine S, Andrews NC. Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J Clin Invest. 2005;115:1258-66.
-
(2005)
J Clin Invest.
, vol.115
, pp. 1258-1266
-
-
Gunshin, H.1
Fujiwara, Y.2
Custodio, A.O.3
Direnzo, C.4
Robine, S.5
Andrews, N.C.6
-
31
-
-
0035025882
-
Cellular localization of divalent metal transporter DMT-1 in rat kidney
-
Ferguson CJ, Wareing M, Ward DT, Green R, Smith CP, Riccardi D. Cellular localization of divalent metal transporter DMT-1 in rat kidney. Am J Physiol Renal Physiol. 2001;280:F803-14.
-
(2001)
Am J Physiol Renal Physiol.
, vol.280
, pp. F803-F814
-
-
Ferguson, C.J.1
Wareing, M.2
Ward, D.T.3
Green, R.4
Smith, C.P.5
Riccardi, D.6
-
32
-
-
0037126002
-
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function
-
Hubert N, Hentze MW. Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc Natl Acad Sci USA. 2002;99:12345-50.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, pp. 12345-12350
-
-
Hubert, N.1
Hentze, M.W.2
-
33
-
-
34147145982
-
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1
-
Ludwiczek S, Theurl I, Muckenthaler MU, et al. Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1. Nat Med. 2007;13:448-54.
-
(2007)
Nat Med.
, vol.13
, pp. 448-454
-
-
Ludwiczek, S.1
Theurl, I.2
Muckenthaler, M.U.3
-
34
-
-
0038711587
-
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
-
Jeong SY, David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J Biol Chem. 2003;278:27144-8.
-
(2003)
J Biol Chem.
, vol.278
, pp. 27144-27148
-
-
Jeong, S.Y.1
David, S.2
-
35
-
-
24144459870
-
Identification of an intestinal heme transporter
-
Shayeghi M, Latunde-Dada GO, Oakhill JS, et al. Identification of an intestinal heme transporter. Cell. 2005;122:789-801.
-
(2005)
Cell.
, vol.122
, pp. 789-801
-
-
Shayeghi, M.1
Latunde-Dada, G.O.2
Oakhill, J.S.3
-
36
-
-
33751244559
-
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
-
Qiu A, Jansen M, Sakaris A, et al. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell. 2006;127:917-28.
-
(2006)
Cell.
, vol.127
, pp. 917-928
-
-
Qiu, A.1
Jansen, M.2
Sakaris, A.3
-
37
-
-
18744397511
-
An iron delivery pathway mediated by a lipocalin
-
Yang J, Goetz D, Li JY, et al. An iron delivery pathway mediated by a lipocalin. Mol Cell. 2002;10:1045-56.
-
(2002)
Mol Cell.
, vol.10
, pp. 1045-1056
-
-
Yang, J.1
Goetz, D.2
Li, J.Y.3
-
38
-
-
29244457829
-
24p3 and its receptor: dawn of a new iron age?
-
Richardson DR. 24p3 and its receptor: dawn of a new iron age? Cell. 2005;123:1175-7.
-
(2005)
Cell.
, vol.123
, pp. 1175-1177
-
-
Richardson, D.R.1
-
39
-
-
32444442757
-
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury
-
Berger T, Togawa A, Duncan GS, et al. Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc Natl Acad Sci USA. 2006;103:1834-9.
-
(2006)
Proc Natl Acad Sci USA.
, vol.103
, pp. 1834-1839
-
-
Berger, T.1
Togawa, A.2
Duncan, G.S.3
-
40
-
-
29244492306
-
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake
-
Devireddy LR, Gazin C, Zhu X, Green MR. A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell. 2005;123:1293-305.
-
(2005)
Cell.
, vol.123
, pp. 1293-1305
-
-
Devireddy, L.R.1
Gazin, C.2
Zhu, X.3
Green, M.R.4
-
41
-
-
12744272449
-
The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake
-
Hvidberg V, Jacobsen C, Strong RK, Cowland JB, Moestrup SK, Borregaard N. The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett. 2005;579:773-7.
-
(2005)
FEBS Lett.
, vol.579
, pp. 773-777
-
-
Hvidberg, V.1
Jacobsen, C.2
Strong, R.K.3
Cowland, J.B.4
Moestrup, S.K.5
Borregaard, N.6
-
42
-
-
0032857025
-
Megalin knockout mice as an animal model of low molecular weight proteinuria
-
Leheste JR, Rolinski B, Vorum H, et al. Megalin knockout mice as an animal model of low molecular weight proteinuria. Am J Pathol. 1999;155:1361-70.
-
(1999)
Am J Pathol.
, vol.155
, pp. 1361-1370
-
-
Leheste, J.R.1
Rolinski, B.2
Vorum, H.3
-
43
-
-
0036155055
-
Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin
-
Gburek J, Verroust PJ, Willnow TE, et al. Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin. J Am Soc Nephrol. 2002;13:423-30.
-
(2002)
J Am Soc Nephrol.
, vol.13
, pp. 423-430
-
-
Gburek, J.1
Verroust, P.J.2
Willnow, T.E.3
-
44
-
-
0141461407
-
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
-
Oudit GY, Sun H, Trivieri MG, et al. L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nat Med. 2003;9:1187-94.
-
(2003)
Nat Med.
, vol.9
, pp. 1187-1194
-
-
Oudit, G.Y.1
Sun, H.2
Trivieri, M.G.3
-
45
-
-
1642545649
-
Role of transient receptor potential canonical 6 (TRPC6) in non-transferrin-bound iron uptake in neuronal phenotype PC12 cells
-
Mwanjewe J, Grover AK. Role of transient receptor potential canonical 6 (TRPC6) in non-transferrin-bound iron uptake in neuronal phenotype PC12 cells. Biochem J. 2004;378:975-82.
-
(2004)
Biochem J.
, vol.378
, pp. 975-982
-
-
Mwanjewe, J.1
Grover, A.K.2
-
46
-
-
33646351076
-
Role of L-type Ca2+ channels in iron transport and ironoverload cardiomyopathy
-
Oudit GY, Trivieri MG, Khaper N, Liu PP, Backx PH. Role of L-type Ca2+ channels in iron transport and ironoverload cardiomyopathy. J Mol Med. 2006;84:349-64.
-
(2006)
J Mol Med.
, vol.84
, pp. 349-364
-
-
Oudit, G.Y.1
Trivieri, M.G.2
Khaper, N.3
Liu, P.P.4
Backx, P.H.5
-
47
-
-
0033229699
-
Regulation of intracellular iron metabolism in human erythroid precursors by internalized extracellular ferritin
-
Meyron-Holtz EG, Vaisman B, Cabantchik ZI, et al. Regulation of intracellular iron metabolism in human erythroid precursors by internalized extracellular ferritin. Blood. 1999;94:3205-11.
-
(1999)
Blood.
, vol.94
, pp. 3205-3211
-
-
Meyron-Holtz, E.G.1
Vaisman, B.2
Cabantchik, Z.I.3
-
48
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem. 2000;275:19906-12.
-
(2000)
J Biol Chem.
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.J.2
-
49
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 2000;403:776-81.
-
(2000)
Nature.
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
50
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell. 2000;5:299-309.
-
(2000)
Mol Cell.
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
-
51
-
-
0032909207
-
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
-
Vulpe CD, Kuo YM, Murphy TL, et al. Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat Genet. 1999;21:195-9.
-
(1999)
Nat Genet.
, vol.21
, pp. 195-199
-
-
Vulpe, C.D.1
Kuo, Y.M.2
Murphy, T.L.3
-
52
-
-
33645070287
-
Unexpected role of ceruloplasmin in intestinal iron absorption
-
Cherukuri S, Potla R, Sarkar J, Nurko S, Harris ZL, Fox PL. Unexpected role of ceruloplasmin in intestinal iron absorption. Cell Metab. 2005;2:309-19.
-
(2005)
Cell Metab.
, vol.2
, pp. 309-319
-
-
Cherukuri, S.1
Potla, R.2
Sarkar, J.3
Nurko, S.4
Harris, Z.L.5
Fox, P.L.6
-
53
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005;1:191-200.
-
(2005)
Cell Metab.
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
-
54
-
-
0242521527
-
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression
-
Lymboussaki A, Pignatti E, Montosi G, Garuti C, Haile DJ, Pietrangelo A. The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression. J Hepatol. 2003;39:710-5.
-
(2003)
J Hepatol.
, vol.39
, pp. 710-715
-
-
Lymboussaki, A.1
Pignatti, E.2
Montosi, G.3
Garuti, C.4
Haile, D.J.5
Pietrangelo, A.6
-
55
-
-
0344974223
-
Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation
-
Liu XB, Hill P, Haile DJ. Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation. Blood Cells Mol Dis. 2002;29:315-26.
-
(2002)
Blood Cells Mol Dis.
, vol.29
, pp. 315-326
-
-
Liu, X.B.1
Hill, P.2
Haile, D.J.3
-
56
-
-
37449009448
-
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
-
Galy B. Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. Cell Metab. 2008;7:79-85.
-
(2008)
Cell Metab.
, vol.7
, pp. 79-85
-
-
Galy, B.1
-
57
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090-3.
-
(2004)
Science.
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
58
-
-
36349028180
-
Hemochromatosis: an endocrine liver disease
-
Pietrangelo A. Hemochromatosis: an endocrine liver disease. Hepatology. 2007;46:1291-301.
-
(2007)
Hepatology.
, vol.46
, pp. 1291-1301
-
-
Pietrangelo, A.1
-
60
-
-
33846650973
-
Molecular control of iron transport
-
Ganz T. Molecular control of iron transport. J Am Soc Nephrol. 2007;18:394-400.
-
(2007)
J Am Soc Nephrol.
, vol.18
, pp. 394-400
-
-
Ganz, T.1
-
61
-
-
33751103909
-
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome
-
De Domenico I, Vaughn MB, Li L, et al. Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. EMBO J. 2006;25:5396-404.
-
(2006)
EMBO J.
, vol.25
, pp. 5396-5404
-
-
De Domenico, I.1
Vaughn, M.B.2
Li, L.3
-
62
-
-
4544264523
-
Identification of a human heme exporter that is essential for erythropoiesis
-
Quigley JG, Yang Z, Worthington MT, et al. Identification of a human heme exporter that is essential for erythropoiesis. Cell. 2004;118:757-66.
-
(2004)
Cell.
, vol.118
, pp. 757-766
-
-
Quigley, J.G.1
Yang, Z.2
Worthington, M.T.3
-
63
-
-
38949097546
-
A heme export protein is required for red blood cell differentiation and iron homeostasis
-
Keel SB, Doty RT, Yang Z, et al. A heme export protein is required for red blood cell differentiation and iron homeostasis. Science. 2008;319:825-8.
-
(2008)
Science.
, vol.319
, pp. 825-828
-
-
Keel, S.B.1
Doty, R.T.2
Yang, Z.3
-
64
-
-
8644244745
-
Probing the iron pool. Focus on "detection of intracellular iron by its regulatory effect"
-
Andrews NC. Probing the iron pool. Focus on "detection of intracellular iron by its regulatory effect". Am J Physiol Cell Physiol. 2004;287:C1537-8.
-
(2004)
Am J Physiol Cell Physiol.
, vol.287
, pp. C1537-C1538
-
-
Andrews, N.C.1
-
65
-
-
33745205646
-
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage
-
Kurz T, Gustafsson B, Brunk UT. Intralysosomal iron chelation protects against oxidative stress-induced cellular damage. FEBS J. 2006;273:3106-17.
-
(2006)
FEBS J.
, vol.273
, pp. 3106-3117
-
-
Kurz, T.1
Gustafsson, B.2
Brunk, U.T.3
-
66
-
-
14644401128
-
S-nitrosothiols: cellular formation and transport
-
Zhang Y, Hogg N. S-nitrosothiols: cellular formation and transport. Free Radic Biol Med. 2005;38:831-8.
-
(2005)
Free Radic Biol Med.
, vol.38
, pp. 831-838
-
-
Zhang, Y.1
Hogg, N.2
-
67
-
-
0037093202
-
Regulation of ferritin genes and protein
-
Torti FM, Torti SV. Regulation of ferritin genes and protein. Blood. 2002;99:3505-5316.
-
(2002)
Blood.
, vol.99
, pp. 3505-5316
-
-
Torti, F.M.1
Torti, S.V.2
-
68
-
-
0017581936
-
Ferritin: an iron-storage molecule
-
Harrison PM. Ferritin: an iron-storage molecule. Semin Hematol. 1977;14:55-70.
-
(1977)
Semin Hematol.
, vol.14
, pp. 55-70
-
-
Harrison, P.M.1
-
69
-
-
0035816608
-
A human mitochondrial ferritin encoded by an intronless gene
-
Levi S, Corsi B, Bosisio M, et al. A human mitochondrial ferritin encoded by an intronless gene. J Biol Chem. 2001;276:24437-40.
-
(2001)
J Biol Chem.
, vol.276
, pp. 24437-24440
-
-
Levi, S.1
Corsi, B.2
Bosisio, M.3
-
70
-
-
35548967459
-
Mitochondrial ferritin expression in adult mouse tissues
-
Santambrogio P, Biasiotto G, Sanvito F, Olivieri S, Arosio P, Levi S. Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem. 2007;55:1129-37.
-
(2007)
J Histochem Cytochem.
, vol.55
, pp. 1129-1137
-
-
Santambrogio, P.1
Biasiotto, G.2
Sanvito, F.3
Olivieri, S.4
Arosio, P.5
Levi, S.6
-
71
-
-
14944358625
-
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis
-
Nie G, Sheftel AD, Kim SF, Ponka P. Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis. Blood. 2005;105:2161-7.
-
(2005)
Blood.
, vol.105
, pp. 2161-2167
-
-
Nie, G.1
Sheftel, A.D.2
Kim, S.F.3
Ponka, P.4
-
72
-
-
0037372442
-
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia
-
Cazzola M, Invernizzi R, Bergamaschi G, et al. Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood. 2003;101:1996-2000.
-
(2003)
Blood.
, vol.101
, pp. 1996-2000
-
-
Cazzola, M.1
Invernizzi, R.2
Bergamaschi, G.3
-
73
-
-
34347375300
-
Direct interorganellar transfer of iron from endosome to mitochondrion
-
Sheftel AD, Zhang AS, Brown C, Shirihai OS, Ponka P. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood. 2007;110:125-32.
-
(2007)
Blood.
, vol.110
, pp. 125-132
-
-
Sheftel, A.D.1
Zhang, A.S.2
Brown, C.3
Shirihai, O.S.4
Ponka, P.5
-
74
-
-
33646548593
-
Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis
-
Schranzhofer M, Schifrer M, Cabrera JA, et al. Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood. 2006;107:4159-67.
-
(2006)
Blood.
, vol.107
, pp. 4159-4167
-
-
Schranzhofer, M.1
Schifrer, M.2
Cabrera, J.A.3
-
76
-
-
14944387002
-
Iron trafficking in the mitochondrion: novel pathways revealed by disease
-
Napier I, Ponka P, Richardson DR. Iron trafficking in the mitochondrion: novel pathways revealed by disease. Blood. 2005;105:1867-74.
-
(2005)
Blood.
, vol.105
, pp. 1867-1874
-
-
Napier, I.1
Ponka, P.2
Richardson, D.R.3
-
77
-
-
17144378216
-
Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis
-
Rouault TA, Tong WH. Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis. Nat Rev Mol Cell Biol. 2005;6:345-51.
-
(2005)
Nat Rev Mol Cell Biol.
, vol.6
, pp. 345-351
-
-
Rouault, T.A.1
Tong, W.H.2
-
78
-
-
33751177803
-
Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms
-
Lill R, Mühlenhoff U. Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms. Annu Rev Cell Dev Biol. 2006;22:457-86.
-
(2006)
Annu Rev Cell Dev Biol.
, vol.22
, pp. 457-486
-
-
Lill, R.1
Mühlenhoff, U.2
-
79
-
-
47249094614
-
Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases
-
Lill R, Mühlenhoff U. Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases. Annu Rev Biochem. 2008;77:669-700.
-
(2008)
Annu Rev Biochem.
, vol.77
, pp. 669-700
-
-
Lill, R.1
Mühlenhoff, U.2
-
80
-
-
33746864096
-
Molecular control of vertebrate iron homeostasis by iron regulatory proteins
-
Wallander ML, Leibold EA, Eisenstein RS. Molecular control of vertebrate iron homeostasis by iron regulatory proteins. Biochim Biophys Acta. 2006;1763(7):668-89.
-
(2006)
Biochim Biophys Acta.
, vol.1763
, Issue.7
, pp. 668-689
-
-
Wallander, M.L.1
Leibold, E.A.2
Eisenstein, R.S.3
-
81
-
-
0027405813
-
Regulation by heme of mitochondrial protein transport through a conserved amino acid motif
-
Lathrop JT, Timko MP. Regulation by heme of mitochondrial protein transport through a conserved amino acid motif. Science. 1993;259:522-5.
-
(1993)
Science.
, vol.259
, pp. 522-525
-
-
Lathrop, J.T.1
Timko, M.P.2
-
82
-
-
33749530252
-
Identification of a mammalian mitochondrial porphyrin transporter
-
Krishnamurthy PC, Du G, Fukuda Y, et al. Identification of a mammalian mitochondrial porphyrin transporter. Nature. 2006;443:586-9.
-
(2006)
Nature.
, vol.443
, pp. 586-589
-
-
Krishnamurthy, P.C.1
Du, G.2
Fukuda, Y.3
-
83
-
-
0034625457
-
MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis
-
Mitsuhashi N, Miki T, Senbongi H, et al. MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis. J Biol Chem. 2000;275:17536-40.
-
(2000)
J Biol Chem.
, vol.275
, pp. 17536-17540
-
-
Mitsuhashi, N.1
Miki, T.2
Senbongi, H.3
-
84
-
-
0032414310
-
Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p
-
Csere P, Lill R, Kispal G. Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p. FEBS Lett. 1998;441:266-70.
-
(1998)
FEBS Lett.
, vol.441
, pp. 266-270
-
-
Csere, P.1
Lill, R.2
Kispal, G.3
-
85
-
-
33644772614
-
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulphur cluster biogenesis
-
Pondarre C, Antiochos BB, Campagna DR, et al. The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulphur cluster biogenesis. Hum Mol Genet. 2006;15:953-64.
-
(2006)
Hum Mol Genet.
, vol.15
, pp. 953-964
-
-
Pondarre, C.1
Antiochos, B.B.2
Campagna, D.R.3
-
86
-
-
34147158934
-
Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis
-
Pondarre C, Campagna DR, Antiochos B, Sikorski L, Mulhern H, Fleming MD. Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis. Blood. 2007;109:3567-9.
-
(2007)
Blood.
, vol.109
, pp. 3567-3569
-
-
Pondarre, C.1
Campagna, D.R.2
Antiochos, B.3
Sikorski, L.4
Mulhern, H.5
Fleming, M.D.6
-
87
-
-
34147173749
-
Measurement of VDAC permeability in intact mitochondria and in reconstituted systems
-
Colombini M. Measurement of VDAC permeability in intact mitochondria and in reconstituted systems. Methods Cell Biol. 2007;80:241-60.
-
(2007)
Methods Cell Biol.
, vol.80
, pp. 241-260
-
-
Colombini, M.1
-
88
-
-
0032511189
-
The preprotein translocation channel of the outer membrane of mitochondria
-
Künkele KP, Heins S, Dembowski M, et al. The preprotein translocation channel of the outer membrane of mitochondria. Cell. 1998;93:1009-19.
-
(1998)
Cell.
, vol.93
, pp. 1009-1019
-
-
Künkele, K.P.1
Heins, S.2
Dembowski, M.3
-
89
-
-
34548095406
-
Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane
-
Paterson JK, Shukla S, Black CM, et al. Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane. Biochemistry. 2007;46:9443-52.
-
(2007)
Biochemistry.
, vol.46
, pp. 9443-9452
-
-
Paterson, J.K.1
Shukla, S.2
Black, C.M.3
-
90
-
-
40849126574
-
Human ABC transporter isoform B6 (ABCB6) localizes primarily in the golgi apparatus
-
Tsuchida M, Emi Y, Kida Y, Sakaguchi M. Human ABC transporter isoform B6 (ABCB6) localizes primarily in the golgi apparatus. Biochem Biophys Res Commun. 2008;369:369-75.
-
(2008)
Biochem Biophys Res Commun.
, vol.369
, pp. 369-375
-
-
Tsuchida, M.1
Emi, Y.2
Kida, Y.3
Sakaguchi, M.4
-
91
-
-
39349100294
-
Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6
-
Jalil YA, Ritz V, Jakimenko A, et al. Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6. Am J Physiol Cell Physiol. 2008;294:C579-90.
-
(2008)
Am J Physiol Cell Physiol.
, vol.294
, pp. C579-C590
-
-
Jalil, Y.A.1
Ritz, V.2
Jakimenko, A.3
-
92
-
-
34548137051
-
Intracellular trafficking of porphyrins
-
Hamza I. Intracellular trafficking of porphyrins. ACS Chem Biol. 2006;1:627-9.
-
(2006)
ACS Chem Biol.
, vol.1
, pp. 627-629
-
-
Hamza, I.1
-
93
-
-
2442563409
-
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis
-
Koch M, Breithaupt C, Kiefersauer R, Freigang J, Huber R, Messerschmidt A. Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO J. 2004;23:1720-8.
-
(2004)
EMBO J.
, vol.23
, pp. 1720-1728
-
-
Koch, M.1
Breithaupt, C.2
Kiefersauer, R.3
Freigang, J.4
Huber, R.5
Messerschmidt, A.6
-
94
-
-
0034746571
-
The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis
-
Wu CK, Dailey HA, Rose JP, Burden A, Sellers VM, Wang BC. The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis. Nat Struct Biol. 2001;8:156-60.
-
(2001)
Nat Struct Biol.
, vol.8
, pp. 156-160
-
-
Wu, C.K.1
Dailey, H.A.2
Rose, J.P.3
Burden, A.4
Sellers, V.M.5
Wang, B.C.6
-
95
-
-
0033516467
-
Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria
-
Lange H, Kispal G, Lill R. Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria. J Biol Chem. 1999;274:18989-96.
-
(1999)
J Biol Chem.
, vol.274
, pp. 18989-18996
-
-
Lange, H.1
Kispal, G.2
Lill, R.3
-
96
-
-
0036670802
-
Terminal steps of haem biosynthesis
-
Dailey HA. Terminal steps of haem biosynthesis. Biochem Soc Trans. 2002;30:590-5.
-
(2002)
Biochem Soc Trans.
, vol.30
, pp. 590-595
-
-
Dailey, H.A.1
-
97
-
-
0037025331
-
Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
-
Foury F, Roganti T. Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J Biol Chem. 2002;277:24475-83.
-
(2002)
J Biol Chem.
, vol.277
, pp. 24475-24483
-
-
Foury, F.1
Roganti, T.2
-
98
-
-
17044451174
-
A specific role of the yeast mitochondrial carriers Mrs3/4p in mitochondrial iron acquisition under iron-limiting conditions
-
Mühlenhoff U, Stadler J, Richhardt N, et al. A specific role of the yeast mitochondrial carriers Mrs3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem. 2003;278:40612-20.
-
(2003)
J Biol Chem.
, vol.278
, pp. 40612-40620
-
-
Mühlenhoff, U.1
Stadler, J.2
Richhardt, N.3
-
99
-
-
4043084194
-
A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism
-
Li L, Kaplan J. A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. J Biol Chem. 2004;279(32):33653-61.
-
(2004)
J Biol Chem.
, vol.279
, Issue.32
, pp. 33653-33661
-
-
Li, L.1
Kaplan, J.2
-
100
-
-
33644748145
-
Mitoferrin is essential for erythroid iron assimilation
-
Shaw GC, Cope JJ, Li L, et al. Mitoferrin is essential for erythroid iron assimilation. Nature. 2006;440:96-100.
-
(2006)
Nature.
, vol.440
, pp. 96-100
-
-
Shaw, G.C.1
Cope, J.J.2
Li, L.3
-
101
-
-
0037155866
-
Mitochondrial ferredoxin is required for heme A synthesis in Saccharomyces cerevisiae
-
Barros MH, Nobrega FG, Tzagoloff A. Mitochondrial ferredoxin is required for heme A synthesis in Saccharomyces cerevisiae . J Biol Chem. 2002;277:9997-10002.
-
(2002)
J Biol Chem.
, vol.277
, pp. 9997-10002
-
-
Barros, M.H.1
Nobrega, F.G.2
Tzagoloff, A.3
-
102
-
-
0035831217
-
Involvement of mitochondrial ferredoxin and Cox15p in hydroxylation of heme O
-
Barros MH, Carlson CG, Glerum DM, Tzagoloff A. Involvement of mitochondrial ferredoxin and Cox15p in hydroxylation of heme O. FEBS Lett. 2001;492:133-8.
-
(2001)
FEBS Lett.
, vol.492
, pp. 133-138
-
-
Barros, M.H.1
Carlson, C.G.2
Glerum, D.M.3
Tzagoloff, A.4
-
103
-
-
14744294785
-
Iron-sulfur protein biogenesis in eukaryotes
-
Lill R, Mühlenhoff U. Iron-sulfur protein biogenesis in eukaryotes. Trends Biochem Sci. 2005;30:133-41.
-
(2005)
Trends Biochem Sci.
, vol.30
, pp. 133-141
-
-
Lill, R.1
Mühlenhoff, U.2
-
104
-
-
0141737067
-
Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p
-
Mühlenhoff U, Gerber J, Richhardt N, Lill R. Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J. 2003;22:4815-25.
-
(2003)
EMBO J.
, vol.22
, pp. 4815-4825
-
-
Mühlenhoff, U.1
Gerber, J.2
Richhardt, N.3
Lill, R.4
-
105
-
-
0033621156
-
Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae
-
Schilke B, Voisine C, Beinert H, Craig E. Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae . Proc Natl Acad Sci USA. 1999;96:10206-11.
-
(1999)
Proc Natl Acad Sci USA.
, vol.96
, pp. 10206-10211
-
-
Schilke, B.1
Voisine, C.2
Beinert, H.3
Craig, E.4
-
106
-
-
0033544704
-
Saccharomyces cerevisiae ISU1 and ISU2: members of a wellconserved gene family for iron-sulfur cluster assembly
-
Garland SA, Hoff K, Vickery LE, Culotta VC. Saccharomyces cerevisiae ISU1 and ISU2: members of a wellconserved gene family for iron-sulfur cluster assembly. J Mol Biol. 1999;294:897-907.
-
(1999)
J Mol Biol.
, vol.294
, pp. 897-907
-
-
Garland, S.A.1
Hoff, K.2
Vickery, L.E.3
Culotta, V.C.4
-
107
-
-
0033565665
-
The mitochondrial proteins Atm1p and Nfs1p are required for biogenesis of cytosolic Fe/S proteins
-
Kispal G, Csere P, Prohl C, Lill R. The mitochondrial proteins Atm1p and Nfs1p are required for biogenesis of cytosolic Fe/S proteins. EMBO J. 1999;18:3981-9.
-
(1999)
EMBO J.
, vol.18
, pp. 3981-3989
-
-
Kispal, G.1
Csere, P.2
Prohl, C.3
Lill, R.4
-
108
-
-
30444449009
-
Essential role of Isd11 in iron-sulfur cluster synthesis on Isu scaffold proteins
-
Wiedemann N, Urzica E, Guiard B, et al. Essential role of Isd11 in iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J. 2006;25:184-95.
-
(2006)
EMBO J.
, vol.25
, pp. 184-195
-
-
Wiedemann, N.1
Urzica, E.2
Guiard, B.3
-
109
-
-
30444433568
-
The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria
-
Adam AC, Bornhövd C, Prokisch H, Neupert W, Hell K. The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J. 2006;25:174-83.
-
(2006)
EMBO J.
, vol.25
, pp. 174-183
-
-
Adam, A.C.1
Bornhövd, C.2
Prokisch, H.3
Neupert, W.4
Hell, K.5
-
110
-
-
34447316711
-
Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones
-
Shan Y, Napoli E, Cortopassi G. Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones. Hum Mol Genet. 2007;16(8):929-41.
-
(2007)
Hum Mol Genet.
, vol.16
, Issue.8
, pp. 929-941
-
-
Shan, Y.1
Napoli, E.2
Cortopassi, G.3
-
111
-
-
0141623560
-
An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1
-
Gerber J, Mühlenhoff U, Lill R. An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1. EMBO Rep. 2003;4:906-11.
-
(2003)
EMBO Rep.
, vol.4
, pp. 906-911
-
-
Gerber, J.1
Mühlenhoff, U.2
Lill, R.3
-
112
-
-
33744956665
-
Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU in iron-sulfur cluster assembly
-
Li K, Tong WH, Hughes RM, Rouault TA. Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU in iron-sulfur cluster assembly. J Biol Chem. 2006;281:12344-51.
-
(2006)
J Biol Chem.
, vol.281
, pp. 12344-12351
-
-
Li, K.1
Tong, W.H.2
Hughes, R.M.3
Rouault, T.A.4
-
113
-
-
33746509655
-
Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation
-
Biederbick A, Stehling O, Rösser R, et al. Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation. Mol Cell Biol. 2006;26:5675-87.
-
(2006)
Mol Cell Biol.
, vol.26
, pp. 5675-5687
-
-
Biederbick, A.1
Stehling, O.2
Rösser, R.3
-
114
-
-
33644623262
-
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis
-
Tong WH, Rouault TA. Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. Cell Metab. 2006;3:199-210.
-
(2006)
Cell Metab.
, vol.3
, pp. 199-210
-
-
Tong, W.H.1
Rouault, T.A.2
-
115
-
-
34247882804
-
Human frataxin: iron and ferrochelatase binding surface
-
Bencze KZ, Yoon T, Millan-Pacheco C, et al. Human frataxin: iron and ferrochelatase binding surface. Chem Commun (Camb). 2007;14:1798-800.
-
(2007)
Chem Commun (Camb).
, vol.14
, pp. 1798-1800
-
-
Bencze, K.Z.1
Yoon, T.2
Millan-Pacheco, C.3
-
116
-
-
9744248303
-
Iron-sulfur protein maturation in human cells: evidence for a function of frataxin
-
Stehling O, Elsässer HP, Brückel B, Mühlenhoff U, Lill R. Iron-sulfur protein maturation in human cells: evidence for a function of frataxin. Hum Mol Genet. 2004;13:3007-15.
-
(2004)
Hum Mol Genet.
, vol.13
, pp. 3007-3015
-
-
Stehling, O.1
Elsässer, H.P.2
Brückel, B.3
Mühlenhoff, U.4
Lill, R.5
-
117
-
-
33747330134
-
Mrs3p, Mrs4p, and frataxin provide iron for Fe-S cluster synthesis in mitochondria
-
Zhang Y, Lyver ER, Knight SA, Pain D, Lesuisse E, Dancis A. Mrs3p, Mrs4p, and frataxin provide iron for Fe-S cluster synthesis in mitochondria. J Biol Chem. 2006;281:22493-502.
-
(2006)
J Biol Chem.
, vol.281
, pp. 22493-22502
-
-
Zhang, Y.1
Lyver, E.R.2
Knight, S.A.3
Pain, D.4
Lesuisse, E.5
Dancis, A.6
-
118
-
-
0033953353
-
A mitochondrial ferredoxin is essential for biogenesis of intra-and extramitochondrial Fe/S proteins
-
Lange H, Kispal G, Kaut A, Lill R. A mitochondrial ferredoxin is essential for biogenesis of intra-and extramitochondrial Fe/S proteins. Proc Natl Acad Sci USA. 2000;97:1050-5.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, pp. 1050-1055
-
-
Lange, H.1
Kispal, G.2
Kaut, A.3
Lill, R.4
-
119
-
-
0035846961
-
Adrenodoxin reductase homolog (Arh1p) of yeast mitochondria required for iron homeostasis
-
Li J, Saxena S, Pain D, Dancis A. Adrenodoxin reductase homolog (Arh1p) of yeast mitochondria required for iron homeostasis. J Biol Chem. 2001;276:1503-9.
-
(2001)
J Biol Chem.
, vol.276
, pp. 1503-1509
-
-
Li, J.1
Saxena, S.2
Pain, D.3
Dancis, A.4
-
120
-
-
0020411223
-
Steroidogenic electron transport in adrenal cortex mitochondria
-
Lambeth JD, Seybert DW, Lancaster JRJ, Salerno JC, Kamin H. Steroidogenic electron transport in adrenal cortex mitochondria. Mol Cell Biochem. 1985;45:13-31.
-
(1985)
Mol Cell Biochem.
, vol.45
, pp. 13-31
-
-
Lambeth, J.D.1
Seybert, D.W.2
Lancaster, J.R.J.3
Salerno, J.C.4
Kamin, H.5
-
121
-
-
0034717943
-
Intramitochondrial cholesterol transfer
-
Stocco DM. Intramitochondrial cholesterol transfer. Biochim Biophys Acta. 2000;1486:184-97.
-
(2000)
Biochim Biophys Acta.
, vol.1486
, pp. 184-197
-
-
Stocco, D.M.1
-
122
-
-
0036809412
-
A specialized mitochondrial molecular chaperone system: a role in formation of Fe/S centers
-
Craig EA, Marszalek J. A specialized mitochondrial molecular chaperone system: a role in formation of Fe/S centers. Cell Mol Life Sci. 2002;59(10):1658-65.
-
(2002)
Cell Mol Life Sci.
, vol.59
, Issue.10
, pp. 1658-1665
-
-
Craig, E.A.1
Marszalek, J.2
-
123
-
-
33646342998
-
The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p
-
Dutkiewicz R, Marszalek J, Schilke B, Craig EA, Lill R, Mühlenhoff U. The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p. J Biol Chem. 2006;281:7801-8.
-
(2006)
J Biol Chem.
, vol.281
, pp. 7801-7808
-
-
Dutkiewicz, R.1
Marszalek, J.2
Schilke, B.3
Craig, E.A.4
Lill, R.5
Mühlenhoff, U.6
-
124
-
-
3142716203
-
Sequence-specific interaction between mitochondrial Fe-S scaffold protein Isu and Hsp70 Ssq1 is essential for their in vivo function
-
Dutkiewicz R, Schilke B, Cheng S, Knieszner H, Craig EA, Marszalek J. Sequence-specific interaction between mitochondrial Fe-S scaffold protein Isu and Hsp70 Ssq1 is essential for their in vivo function. J Biol Chem. 2004;279:29167-74.
-
(2004)
J Biol Chem.
, vol.279
, pp. 29167-29174
-
-
Dutkiewicz, R.1
Schilke, B.2
Cheng, S.3
Knieszner, H.4
Craig, E.A.5
Marszalek, J.6
-
125
-
-
33744948235
-
Characterization of the interaction between the J-protein Jac1 and the scaffold for Fe-S cluster biogenesis, Isu1
-
Andrew AJ, Dutkiewicz R, Knieszner H, Craig EA, Marszalek J. Characterization of the interaction between the J-protein Jac1 and the scaffold for Fe-S cluster biogenesis, Isu1. J Biol Chem. 2006;281:14580-7.
-
(2006)
J Biol Chem.
, vol.281
, pp. 14580-14587
-
-
Andrew, A.J.1
Dutkiewicz, R.2
Knieszner, H.3
Craig, E.A.4
Marszalek, J.5
-
126
-
-
0036226063
-
Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes
-
Rodriguez-Manzaneque MT, Tamarit J, Belli G, Ros J, Herrero E. Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell. 2002;13:1109-21.
-
(2002)
Mol Biol Cell.
, vol.13
, pp. 1109-1121
-
-
Rodriguez-Manzaneque, M.T.1
Tamarit, J.2
Belli, G.3
Ros, J.4
Herrero, E.5
-
127
-
-
23944500052
-
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
-
Wingert RA, Galloway JL, Barut B, et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 2005;436:1035-9.
-
(2005)
Nature.
, vol.436
, pp. 1035-1039
-
-
Wingert, R.A.1
Galloway, J.L.2
Barut, B.3
-
128
-
-
33947624626
-
The ISC proteins Isa1 and Isa2 are required for the function but not for the de novo synthesis of the Fe/S clusters of biotin synthase in Saccharomyces cerevisiae
-
Mühlenhoff U, Gerl MJ, Flauger B, et al. The ISC proteins Isa1 and Isa2 are required for the function but not for the de novo synthesis of the Fe/S clusters of biotin synthase in Saccharomyces cerevisiae . Eukaryot Cell. 2007;6:495-504.
-
(2007)
Eukaryot Cell.
, vol.6
, pp. 495-504
-
-
Mühlenhoff, U.1
Gerl, M.J.2
Flauger, B.3
-
129
-
-
40749086415
-
Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical-SAM enzymes
-
Gelling C, Dawes IW, Richhardt N, Lill R, Mühlenhoff U. Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical-SAM enzymes. Mol Cell Biol. 2007;28:1851-61.
-
(2007)
Mol Cell Biol.
, vol.28
, pp. 1851-1861
-
-
Gelling, C.1
Dawes, I.W.2
Richhardt, N.3
Lill, R.4
Mühlenhoff, U.5
-
130
-
-
35449008450
-
Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues
-
Martelli A, Wattenhofer-Donzé M, Schmucker S, Bouvet S, Reutenauer L, Puccio H. Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues. Hum Mol Genet. 2007;16:2651-8.
-
(2007)
Hum Mol Genet.
, vol.16
, pp. 2651-2658
-
-
Martelli, A.1
Wattenhofer-Donzé, M.2
Schmucker, S.3
Bouvet, S.4
Reutenauer, L.5
Puccio, H.6
-
131
-
-
33845693952
-
Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts
-
Lu C, Cortopassi G. Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts. Arch Biochem Biophys. 2007;457:111-22.
-
(2007)
Arch Biochem Biophys.
, vol.457
, pp. 111-122
-
-
Lu, C.1
Cortopassi, G.2
-
132
-
-
2442707887
-
The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins
-
Gerber J, Neumann K, Prohl C, Mühlenhoff U, Lill R. The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol. 2004;24:4848-57.
-
(2004)
Mol Cell Biol.
, vol.24
, pp. 4848-4857
-
-
Gerber, J.1
Neumann, K.2
Prohl, C.3
Mühlenhoff, U.4
Lill, R.5
-
133
-
-
4344595102
-
Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae
-
Mühlenhoff U, Balk J, Richhardt N, et al. Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae . J Biol Chem. 2004;279:36906-15.
-
(2004)
J Biol Chem.
, vol.279
, pp. 36906-36915
-
-
Mühlenhoff, U.1
Balk, J.2
Richhardt, N.3
-
134
-
-
0034329310
-
Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia (XLSA/A) with disruption of cytosolic iron-sulfur protein maturation
-
Bekri S, Kispal G, Lange H, et al. Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia (XLSA/A) with disruption of cytosolic iron-sulfur protein maturation. Blood. 2000;96:3256-64.
-
(2000)
Blood.
, vol.96
, pp. 3256-3264
-
-
Bekri, S.1
Kispal, G.2
Lange, H.3
-
135
-
-
34147165135
-
RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload
-
Cavadini P, Biasiotto G, Poli M, et al. RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload. Blood. 2007;109:3552-9.
-
(2007)
Blood.
, vol.109
, pp. 3552-3559
-
-
Cavadini, P.1
Biasiotto, G.2
Poli, M.3
-
136
-
-
0034866458
-
An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins
-
Lange H, Lisowsky T, Gerber J, Mühlenhoff U, Kispal G, Lill R. An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins. EMBO Rep. 2001;2:715-20.
-
(2001)
EMBO Rep.
, vol.2
, pp. 715-720
-
-
Lange, H.1
Lisowsky, T.2
Gerber, J.3
Mühlenhoff, U.4
Kispal, G.5
Lill, R.6
-
137
-
-
0037178843
-
Maturation of cytosolic iron-sulfur proteins requires glutathione
-
Sipos K, Lange H, Fekete Z, Ullmann P, Lill R, Kispal G. Maturation of cytosolic iron-sulfur proteins requires glutathione. J Biol Chem. 2002;277:26944-9.
-
(2002)
J Biol Chem.
, vol.277
, pp. 26944-26949
-
-
Sipos, K.1
Lange, H.2
Fekete, Z.3
Ullmann, P.4
Lill, R.5
Kispal, G.6
-
138
-
-
34247247617
-
The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol
-
Netz DJ, Pierik AJ, Stümpfig M, Mühlenhoff U, Lill R. The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol. 2007;3:278-86.
-
(2007)
Nat Chem Biol.
, vol.3
, pp. 278-286
-
-
Netz, D.J.1
Pierik, A.J.2
Stümpfig, M.3
Mühlenhoff, U.4
Lill, R.5
-
139
-
-
2942565619
-
The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins
-
Balk J, Pierik AJ, Aguilar Netz D, Mühlenhoff U, Lill R. The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins. EMBO J. 2004;23:2105-15.
-
(2004)
EMBO J.
, vol.23
, pp. 2105-2115
-
-
Balk, J.1
Pierik, A.J.2
Aguilar Netz, D.3
Mühlenhoff, U.4
Lill, R.5
-
140
-
-
28544450863
-
The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly
-
Balk J, Aguilar Netz DJ, Tepper K, Pierik AJ, Lill R. The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly. Mol Cell Biol. 2005;25:10833-41.
-
(2005)
Mol Cell Biol.
, vol.25
, pp. 10833-10841
-
-
Balk, J.1
Aguilar Netz, D.J.2
Tepper, K.3
Pierik, A.J.4
Lill, R.5
-
141
-
-
35148812715
-
Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis
-
Srinivasan V, Netz DJA, Webert H, et al. Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis. Structure. 2007;15:1246-57.
-
(2007)
Structure.
, vol.15
, pp. 1246-1257
-
-
Srinivasan, V.1
Netz, D.J.A.2
Webert, H.3
-
142
-
-
0032080221
-
Ciao1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1
-
Johnstone RW, Wang J, Tommerup N, Vissing H, Roberts T, Shi Y. Ciao1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1. J Biol Chem. 1998;273:10880-7.
-
(1998)
J Biol Chem.
, vol.273
, pp. 10880-10887
-
-
Johnstone, R.W.1
Wang, J.2
Tommerup, N.3
Vissing, H.4
Roberts, T.5
Shi, Y.6
-
143
-
-
33846298869
-
IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity
-
Huang J, Song D, Flores A, et al. IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity. Biochem J. 2007;401:341-52.
-
(2007)
Biochem J.
, vol.401
, pp. 341-352
-
-
Huang, J.1
Song, D.2
Flores, A.3
-
144
-
-
33745208485
-
Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication
-
Christodoulou A, Lederer CW, Surrey T, Vernos I, Santama N. Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication. J Cell Sci. 2006;119:2035-47.
-
(2006)
J Cell Sci.
, vol.119
, pp. 2035-2047
-
-
Christodoulou, A.1
Lederer, C.W.2
Surrey, T.3
Vernos, I.4
Santama, N.5
-
145
-
-
44049094146
-
A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis
-
Song D, Lee FS. A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis. J Biol Chem. 2008;283:9231-8.
-
(2008)
J Biol Chem.
, vol.283
, pp. 9231-9238
-
-
Song, D.1
Lee, F.S.2
-
146
-
-
50249156530
-
Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis
-
Stehling O, Netz DJA, Niggemeyer B, et al. Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. Mol Cell Biol. 2008;28:5517-28.
-
(2008)
Mol Cell Biol.
, vol.28
, pp. 5517-5528
-
-
Stehling, O.1
Netz, D.J.A.2
Niggemeyer, B.3
-
147
-
-
33746872950
-
Iron uptake in fungi: a system for every source
-
Philpott CC. Iron uptake in fungi: a system for every source. Biochim Biophys Acta. 2006;1763:636-45.
-
(2006)
Biochim Biophys Acta.
, vol.1763
, pp. 636-645
-
-
Philpott, C.C.1
-
149
-
-
0030846021
-
Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin
-
Babcock M, De Silva D, Oaks R, et al. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science. 1997;276:1709-12.
-
(1997)
Science.
, vol.276
, pp. 1709-1712
-
-
Babcock, M.1
De Silva, D.2
Oaks, R.3
-
150
-
-
0030608677
-
The ABC transporter Atm1p is required for mitochondrial iron homeostasis
-
Kispal G, Csere P, Guiard B, Lill R. The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett. 1997;418:346-50.
-
(1997)
FEBS Lett.
, vol.418
, pp. 346-350
-
-
Kispal, G.1
Csere, P.2
Guiard, B.3
Lill, R.4
-
151
-
-
34547763678
-
Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae
-
Ueta R, Fujiwara N, Iwai K, Yamaguchi-Iwai Y. Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae . Mol Biol Cell. 2007;18:2980-90.
-
(2007)
Mol Biol Cell.
, vol.18
, pp. 2980-2990
-
-
Ueta, R.1
Fujiwara, N.2
Iwai, K.3
Yamaguchi-Iwai, Y.4
-
152
-
-
0347379904
-
Pse1p mediates the nuclear import of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae
-
Ueta R, Fukunaka A, Yamaguchi-Iwai Y. Pse1p mediates the nuclear import of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae . J Biol Chem. 2003;278:50120-7.
-
(2003)
J Biol Chem.
, vol.278
, pp. 50120-50127
-
-
Ueta, R.1
Fukunaka, A.2
Yamaguchi-Iwai, Y.3
-
153
-
-
33745872884
-
Role of glutaredoxin-3 and glutaredoxin-4 in the iron-regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae
-
Ojeda L, Keller G, Mühlenhoff U, Rutherford JC, Lill R, Winge DR. Role of glutaredoxin-3 and glutaredoxin-4 in the iron-regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae . J Biol Chem. 2006;281:17661-9.
-
(2006)
J Biol Chem.
, vol.281
, pp. 17661-17669
-
-
Ojeda, L.1
Keller, G.2
Mühlenhoff, U.3
Rutherford, J.C.4
Lill, R.5
Winge, D.R.6
-
154
-
-
33751529756
-
Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae
-
Pujol-Carrion N, Belli G, Herrero E, Nogues A, de la Torre-Ruiz MA. Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae . J Cell Sci. 2006;119:4554-64.
-
(2006)
J Cell Sci.
, vol.119
, pp. 4554-4564
-
-
Pujol-Carrion, N.1
Belli, G.2
Herrero, E.3
Nogues, A.4
de la Torre-Ruiz, M.A.5
-
155
-
-
44849098197
-
Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis
-
Kumanovics A, Chen O, Li L, et al. Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis. J Biol Chem. 2008;283:10276-86.
-
(2008)
J Biol Chem.
, vol.283
, pp. 10276-10286
-
-
Kumanovics, A.1
Chen, O.2
Li, L.3
-
156
-
-
43749114744
-
Cellular and mitochondrial remodeling upon defects in iron-sulfur protein biogenesis
-
Hausmann A, Samans B, Lill R, Mühlenhoff U. Cellular and mitochondrial remodeling upon defects in iron-sulfur protein biogenesis. J Biol Chem. 2008;283:8318-30.
-
(2008)
J Biol Chem.
, vol.283
, pp. 8318-8330
-
-
Hausmann, A.1
Samans, B.2
Lill, R.3
Mühlenhoff, U.4
-
157
-
-
11844257593
-
Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation
-
Puig S, Askeland E, Thiele DJ. Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation. Cell. 2005;120:99-110.
-
(2005)
Cell.
, vol.120
, pp. 99-110
-
-
Puig, S.1
Askeland, E.2
Thiele, D.J.3
-
158
-
-
33746361251
-
The role of iron regulatory proteins in mammalian iron homeostasis and disease
-
Rouault TA. The role of iron regulatory proteins in mammalian iron homeostasis and disease. Nat Chem Biol. 2006;2:406-14.
-
(2006)
Nat Chem Biol.
, vol.2
, pp. 406-414
-
-
Rouault, T.A.1
-
159
-
-
0032920837
-
Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)
-
Allikmets R, Raskind WH, Hutchinson A, Schueck ND, Dean M, Koeller DM. Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A). Hum Mol Genet. 1999;8:743-9.
-
(1999)
Hum Mol Genet.
, vol.8
, pp. 743-749
-
-
Allikmets, R.1
Raskind, W.H.2
Hutchinson, A.3
Schueck, N.D.4
Dean, M.5
Koeller, D.M.6
-
160
-
-
0036603021
-
Friedreich ataxia: a paradigm for mitochondrial diseases
-
Puccio H, Koenig M. Friedreich ataxia: a paradigm for mitochondrial diseases. Curr Opin Genet Dev. 2002;12:272-7.
-
(2002)
Curr Opin Genet Dev.
, vol.12
, pp. 272-277
-
-
Puccio, H.1
Koenig, M.2
-
161
-
-
0035138072
-
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
-
Puccio H, Simon D, Cossee M, et al. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat Genet. 2001;27:181-6.
-
(2001)
Nat Genet.
, vol.27
, pp. 181-186
-
-
Puccio, H.1
Simon, D.2
Cossee, M.3
-
162
-
-
34548013116
-
The human counterpart of zebrafish shiraz shows sideroblasticlike microcytic anemia and iron overload
-
Camaschella C, Campanella A, De Falco L, et al. The human counterpart of zebrafish shiraz shows sideroblasticlike microcytic anemia and iron overload. Blood. 2007;110:1353-8.
-
(2007)
Blood.
, vol.110
, pp. 1353-1358
-
-
Camaschella, C.1
Campanella, A.2
De Falco, L.3
-
163
-
-
44349149346
-
Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect
-
Olsson A, Lind L, Thornell LE, Holmberg M. Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect. Hum Mol Genet. 2008;17:1666-72.
-
(2008)
Hum Mol Genet.
, vol.17
, pp. 1666-1672
-
-
Olsson, A.1
Lind, L.2
Thornell, L.E.3
Holmberg, M.4
-
164
-
-
41149169596
-
Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance
-
Mochel F, Knight MA, Tong WH, et al. Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. Am J Hum Genet. 2008;82:652-60.
-
(2008)
Am J Hum Genet.
, vol.82
, pp. 652-660
-
-
Mochel, F.1
Knight, M.A.2
Tong, W.H.3
-
165
-
-
0034775927
-
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
-
Hwang PM, Bunz F, Yu J, et al. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nat Med. 2001;7:1111-7.
-
(2001)
Nat Med.
, vol.7
, pp. 1111-1117
-
-
Hwang, P.M.1
Bunz, F.2
Yu, J.3
-
166
-
-
28544446058
-
Mitochondrial tumour suppressors: a genetic and biochemical update
-
Gottlieb E, Tomlinson IP. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat Rev Cancer. 2005;5:857-66.
-
(2005)
Nat Rev Cancer.
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
167
-
-
33748428875
-
The DNA repair helicases XPD and FancJ have essential iron-sulfur domains
-
Rudolf J, Makrantoni V, Ingledew WJ, Stark MJ, White MF. The DNA repair helicases XPD and FancJ have essential iron-sulfur domains. Mol Cell. 2006;23:801-8.
-
(2006)
Mol Cell.
, vol.23
, pp. 801-808
-
-
Rudolf, J.1
Makrantoni, V.2
Ingledew, W.J.3
Stark, M.J.4
White, M.F.5
-
168
-
-
33845683300
-
Nucleotide excision repair disorders and the balance between cancer and aging
-
Andressoo JO, Hoeijmakers JH, Mitchell JR. Nucleotide excision repair disorders and the balance between cancer and aging. Cell Cycle. 2006;5:2886-8.
-
(2006)
Cell Cycle.
, vol.5
, pp. 2886-2888
-
-
Andressoo, J.O.1
Hoeijmakers, J.H.2
Mitchell, J.R.3
-
169
-
-
16344377473
-
A role for iron-sulfur clusters in DNA repair
-
Lukianova OA, David SS. A role for iron-sulfur clusters in DNA repair. Curr Opin Chem Biol. 2005;9:145-51.
-
(2005)
Curr Opin Chem Biol.
, vol.9
, pp. 145-151
-
-
Lukianova, O.A.1
David, S.S.2
|