Liv-1 breast cancer protein belongs to new family of histidine-rich membrane proteins with potential to control intracellular ZN2+ homeostasis

IUBMB Life

Volumn 49, Issue 4, 2000, Pages 249-253

  Taylor, K M ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Breast cancer; Histidine rich; Metalloprotease; Transmembrane protein; Zinc

Indexed keywords

MEMBRANE PROTEIN; TUMOR PROTEIN;

AMINO ACID SEQUENCE; BREAST CANCER; HUMAN; NONHUMAN; PROTEIN DOMAIN; PROTEIN FAMILY; REVIEW; ZINC METABOLISM;

EID: 0033931310     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540050033087     Document Type: Review

References (26)

1. Manning, D. L., McClelland, R. A., Knowlden, J. M., Bryant, S., Gee, J. M. W., Green, C. D., Robertson, J. F., Blamey, R. W., Sutherland, R. L., Ormandy, C. L., and Nicholson, R. I. (1995) Differential expression of oestrogen regulated genes in breast cancer. Acta Oncol. 34, 641-646.
2. Taylor, K. M., Hadley, L. J., and Nicholson, R. I. (1999). The LIV-1 gene, implicated in metastatic breast cancer, codes for a histidine-rich transmembrane protein. Br. J. Cancer 80 (Suppl 2), 24.
3. Vallee, B. L., and Falchuk, K. H. (1993) The biochemical basis of zinc physiology. Physiol. Rev. 73, 79-117.
4. McMahon, R. J., and Cousins, R. J. (1998) Mammalian zinc transporters. J. Nutr. 128, 667-670.
5. Eide, D. (1997) Molecular biology of iron and zinc uptake in eukaryotes. Curr. Opin. Cell Biol. 9, 573-577.
6. Guerinot, M. L., and Eide, D. (1999) Zeroing in on zinc uptake in yeast in plants. Curr. Opin. Plant Biol. 2, 244-249.
7. Sheng, Z., and Deutsch, C. (1998) Assembly of ion channels. Methods Enzymol. 293, 17-32.
8. Conley, E, ed. (1999) Ion Channel Factsbook, Vol 1-4. Academic Press, London.
9. Green, W. N. (1999) Ion channel assembly: Creating structures that function. J. Gen. Physiol. 113, 163-170.
10. Eng, B. H., Guerinot, M. L., Eide, D., and Saier, M. H. Jr. (1998) Sequence analyses and phylogenetic characterisation of the ZIP family of metal ion transport proteins. J. Membr. Biol. 166, 1-7.
11. Palmiter, R. D., Cole, T. B., and Findley, S. D. (1996) ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 15, 1784-1791.
12. Palmiter, R. D., Cole, T. B., Quaife, C. J., and Findley, S. D. (1996) ZnT-3, a putative transporter of zinc into synaptic vesicles. Proc. Natl. Acad. Sci. U.S.A. 93, 14934-14939.
13. Hooper, N. M. (1994) Families of zinc metalloproteases. FEBS Letts. 354, 1-6.
14. Dardel, F., Ragusa, S., Lazennec, C., Blanquet, S., and Mainel, T. (1998) Solution structure of nickel-peptide deformylase. J. Mol. Biol. 280, 501-513.
15. Jiang, W., and Bond, J. S. (1992) Families of metallopeptidases and their relationships. FEBS Lett. 312, 112-114.
16. Rawlings, N. D., and Barrett, A. J. (1995) Evolutionary families of metallopeptidases. Methods Enzymol. 248, 183-228.
17. Coleman, J. E. (1998) Zinc enzymes. Curr. Opin. Chem. Biol. 2, 222-234.
18. Stocker, W., and Bode, W. (1995) Structural features of a superfamily of zinc-endopeptidases: The metzincins. Curr. Opin. Struct. Biol. 5, 383-390.
19. Nilsson, I., Saaf, A., Whitley, P., Gafvelin, G., Waller, C., and von Heijne, G. (1998) Proline-induced disruption of a transmembrane alpha-helix in its natural environment. J. Mol. Biol. 284, 1165-1175.
20. Woolfson, D. N., and Williams, D. H. (1990) The influence of proline residues on alpha-helical structure. FEBS Lett. 277, 185-188.
21. Murgia, C., Vespignani, I., Cerase, J., Nobili, F., and Perozzi, G. (1999) Cloning, expression and vesicular localisation of zinc transporter Dri27/ZnT4 in intestinal tissue and cells. Am. J. Physiol. 277, G1231-G1239.
22. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., and Ohara, O. (1999) Prediction of the coding sequences of unidentified genes. XV. DNA Res. 6, 337-345.
23. Cuanjungco, M. P., and Lees, G. J. (1997) Zinc metabolism in the brain: Relevance to human neurodegenerative disorders. Neurobiol. Dis. 4, 137-169.
24. Nelson, N. (1999) Metal ion transporters and homeostasis. EMBO J. 18, 4361-4371.
25. Ferry, G., Boutin, J. A., Hennig, P., Genton, A., Desmet, C., Fauchere, J. L., Atassi, G., and Tucker, G. C. (1998) A zinc chelator inhibiting gelatinases exerts potent in vitro anti-invasive effects. Eur. J. Pharmacol. 351, 225-233.
26. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680.