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Volumn 3, Issue 9-10, 2010, Pages 639-651

Combined zebrafish-yeast chemical-genetic screens reveal gene - Copper-nutrition interactions that modulate melanocyte pigmentation

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; COPPER PROTEIN;

EID: 77956512193     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.005769     Document Type: Article
Times cited : (37)

References (63)
  • 1
    • 67649857201 scopus 로고    scopus 로고
    • Kinase-activating and kinase-impaired cardio-facio-cutaneous syndrome alleles have activity during zebrafish development and are sensitive to small molecule inhibitors
    • Anastasaki, C., Estep, A. L., Marais, R., Rauen, K. A. and Patton, E. E. (2009). Kinase-activating and kinase-impaired cardio-facio-cutaneous syndrome alleles have activity during zebrafish development and are sensitive to small molecule inhibitors. Hum. Mol. Genet. 18, 2543-2554.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2543-2554
    • Anastasaki, C.1    Estep, A.L.2    Marais, R.3    Rauen, K.A.4    Patton, E.E.5
  • 2
    • 34249041230 scopus 로고    scopus 로고
    • Exploring genetic interactions and networks with yeast
    • DOI 10.1038/nrg2085, PII NRG2085
    • Boone, C., Bussey, H. and Andrews, B. J. (2007). Exploring genetic interactions and networks with yeast. Nat. Rev. Genet. 8, 437-449. (Pubitemid 46789246)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.6 , pp. 437-449
    • Boone, C.1    Bussey, H.2    Andrews, B.J.3
  • 3
    • 0038365368 scopus 로고    scopus 로고
    • Analysis of microarray data using Z score transformation
    • Cheadle, C., Vawter, M. P., Freed, W. J. and Becker, K. G. (2003). Analysis of microarray data using Z score transformation. J. Mol. Diagn. 5, 73-81.
    • (2003) J. Mol. Diagn. , vol.5 , pp. 73-81
    • Cheadle, C.1    Vawter, M.P.2    Freed, W.J.3    Becker, K.G.4
  • 4
    • 33747332544 scopus 로고    scopus 로고
    • Malignant melanoma: Genetics and therapeutics in the genomic era
    • Chin, L., Garraway, L. A. and Fisher, D. E. (2006). Malignant melanoma: genetics and therapeutics in the genomic era. Genes Dev. 20, 2149-2182.
    • (2006) Genes Dev. , vol.20 , pp. 2149-2182
    • Chin, L.1    Garraway, L.A.2    Fisher, D.E.3
  • 5
    • 45249100696 scopus 로고    scopus 로고
    • Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays
    • Cook, M. A., Chan, C. K., Jorgensen, P., Ketela, T., So, D., Tyers, M. and Ho, C. Y. (2008). Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays. PLoS One 3, e1546.
    • (2008) PLoS One , vol.3
    • Cook, M.A.1    Chan, C.K.2    Jorgensen, P.3    Ketela, T.4    So, D.5    Tyers, M.6    Ho, C.Y.7
  • 7
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies, S. P., Reddy, H., Caivano, M. and Cohen, P. (2000). Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105.
    • (2000) Biochem. J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 8
    • 0037353864 scopus 로고    scopus 로고
    • Yeast, a model organism for iron and copper metabolism studies
    • DOI 10.1023/A:1020771000746
    • De Freitas, J., Wintz, H., Kim, J. H., Poynton, H., Fox, T. and Vulpe, C. (2003). Yeast, a model organism for iron and copper metabolism studies. Biometals 16, 185-197. (Pubitemid 36140228)
    • (2003) BioMetals , vol.16 , Issue.1 , pp. 185-197
    • De Freitas, J.1    Wintz, H.2    Kim, J.H.3    Poynton, H.4    Fox, T.5    Vulpe, C.6
  • 9
    • 67949092932 scopus 로고    scopus 로고
    • AP-3-dependent trafficking and disease: The first decade
    • Dell'Angelica, E. C. (2009). AP-3-dependent trafficking and disease: the first decade. Curr. Opin. Cell Biol. 21, 552-559.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 552-559
    • Dell'Angelica, E.C.1
  • 11
    • 0032481303 scopus 로고    scopus 로고
    • A novel protein complex promoting formation of functional alpha- and gamma-tubulin
    • DOI 10.1093/emboj/17.4.952
    • Geissler, S., Siegers, K. and Schiebel, E. (1998). A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J. 17, 952-966. (Pubitemid 28077650)
    • (1998) EMBO Journal , vol.17 , Issue.4 , pp. 952-966
    • Geissler, S.1    Siegers, K.2    Schiebel, E.3
  • 15
    • 0030667434 scopus 로고    scopus 로고
    • Integrating genetic approaches into the discovery of anticancer drugs
    • Hartwell, L. H., Szankasi, P., Roberts, C. J., Murray, A. W. and Friend, S. H. (1997). Integrating genetic approaches into the discovery of anticancer drugs. Science 278, 1064-1068.
    • (1997) Science , vol.278 , pp. 1064-1068
    • Hartwell, L.H.1    Szankasi, P.2    Roberts, C.J.3    Murray, A.W.4    Friend, S.H.5
  • 16
    • 43249121573 scopus 로고    scopus 로고
    • The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish
    • DOI 10.1186/1471-213X-8-42
    • Hawkins, T. A., Cavodeassi, F., Erdelyi, F., Szabo, G. and Lele, Z. (2008). The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish. BMC Dev. Biol. 8, 42. (Pubitemid 351652376)
    • (2008) BMC Developmental Biology , vol.8 , pp. 42
    • Hawkins, T.A.1    Cavodeassi, F.2    Erdelyi, F.3    Szabo, G.4    Lele, Z.5
  • 19
    • 72649083530 scopus 로고    scopus 로고
    • Differential contribution of directdeveloping and stem cell-derived melanocytes to the zebrafish larval pigment pattern
    • Hultman, K. A. and Johnson, S. L. (2010). Differential contribution of directdeveloping and stem cell-derived melanocytes to the zebrafish larval pigment pattern. Dev. Biol. 337, 425-431.
    • (2010) Dev. Biol. , vol.337 , pp. 425-431
    • Hultman, K.A.1    Johnson, S.L.2
  • 20
    • 70350650138 scopus 로고    scopus 로고
    • Hitchhiking of Cu/Zn superoxide dismutase to peroxisomes-evidence for a natural piggyback import mechanism in mammals
    • Islinger, M., Li, K. W., Seitz, J., Volkl, A. and Luers, G. H. (2009). Hitchhiking of Cu/Zn superoxide dismutase to peroxisomes-evidence for a natural piggyback import mechanism in mammals. Traffic 10, 1711-1721.
    • (2009) Traffic , vol.10 , pp. 1711-1721
    • Islinger, M.1    Li, K.W.2    Seitz, J.3    Volkl, A.4    Luers, G.H.5
  • 21
    • 36949008164 scopus 로고    scopus 로고
    • Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants
    • Jo, W. J., Loguinov, A., Chang, M., Wintz, H., Nislow, C., Arkin, A. P., Giaever, G. and Vulpe, C. D. (2008). Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants. Toxicol. Sci. 101, 140-151.
    • (2008) Toxicol. Sci. , vol.101 , pp. 140-151
    • Jo, W.J.1    Loguinov, A.2    Chang, M.3    Wintz, H.4    Nislow, C.5    Arkin, A.P.6    Giaever, G.7    Vulpe, C.D.8
  • 22
    • 64849099555 scopus 로고    scopus 로고
    • Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
    • Jo, W. J., Kim, J. H., Oh, E., Jaramillo, D., Holman, P., Loguinov, A. V., Arkin, A. P., Nislow, C., Giaever, G. and Vulpe, C. D. (2009). Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae. BMC Genomics 10, 130.
    • (2009) BMC Genomics , vol.10 , pp. 130
    • Jo, W.J.1    Kim, J.H.2    Oh, E.3    Jaramillo, D.4    Holman, P.5    Loguinov, A.V.6    Arkin, A.P.7    Nislow, C.8    Giaever, G.9    Vulpe, C.D.10
  • 24
    • 33749235493 scopus 로고    scopus 로고
    • Copper deficiency myelopathy (human swayback)
    • Kumar, N. (2006). Copper deficiency myelopathy (human swayback). Mayo Clin. Proc. 81, 1371-1384.
    • (2006) Mayo Clin. Proc. , vol.81 , pp. 1371-1384
    • Kumar, N.1
  • 25
    • 12844269263 scopus 로고    scopus 로고
    • Histone H2A and Spt10 cooperate to regulate induction and autoregulation of the CUP1 metallothionein
    • Kuo, H. C., Moore, J. D. and Krebs, J. E. (2005). Histone H2A and Spt10 cooperate to regulate induction and autoregulation of the CUP1 metallothionein. J. Biol. Chem. 280, 104-111.
    • (2005) J. Biol. Chem. , vol.280 , pp. 104-111
    • Kuo, H.C.1    Moore, J.D.2    Krebs, J.E.3
  • 26
    • 0345240924 scopus 로고    scopus 로고
    • Combined enhancement of microtubule assembly and glucose metabolism in neuronal systems in vitro: Decreased sensitivity to copper toxicity
    • DOI 10.1006/bbrc.1999.1547
    • Liliom, K., Wagner, G., Kovacs, J., Comin, B., Cascante, M., Orosz, F. and Ovadi, J. (1999). Combined enhancement of microtubule assembly and glucose metabolism in neuronal systems in vitro: decreased sensitivity to copper toxicity. Biochem. Biophys. Res. Commun. 264, 605-610. (Pubitemid 29516133)
    • (1999) Biochemical and Biophysical Research Communications , vol.264 , Issue.2 , pp. 605-610
    • Liliom, K.1    Wagner, G.2    Kovacs, J.3    Comin, B.4    Cascante, M.5    Orosz, F.6    Ovadi, J.7
  • 27
    • 0033863554 scopus 로고    scopus 로고
    • Organization-dependent effects of toxic bivalent ions: Microtubule assembly and glycolysis
    • DOI 10.1046/j.1432-1327.2000.01526.x
    • Liliom, K., Wagner, G., Pacz, A., Cascante, M., Kovacs, J. and Ovadi, J. (2000). Organization-dependent effects of toxic bivalent ions microtubule assembly and glycolysis. Eur. J. Biochem. 267, 4731-4739. (Pubitemid 30619463)
    • (2000) European Journal of Biochemistry , vol.267 , Issue.15 , pp. 4731-4739
    • Liliom, K.1    Wagner, G.2    Pacz, A.3    Cascante, M.4    Kovacs, J.5    Ovadi, J.6
  • 28
    • 67049088725 scopus 로고    scopus 로고
    • Pb/Cu effects on the organization of microtubule cytoskeleton in interphase and mitotic cells of Allium sativum L
    • Liu, D., Xue, P., Meng, Q., Zou, J., Gu, J. and Jiang, W. (2009). Pb/Cu effects on the organization of microtubule cytoskeleton in interphase and mitotic cells of Allium sativum L. Plant Cell Rep. 28, 695-702.
    • (2009) Plant Cell Rep. , vol.28 , pp. 695-702
    • Liu, D.1    Xue, P.2    Meng, Q.3    Zou, J.4    Gu, J.5    Jiang, W.6
  • 30
    • 34547782810 scopus 로고    scopus 로고
    • Copper and iron disorders of the brain
    • Madsen, E. and Gitlin, J. D. (2007a). Copper and iron disorders of the brain. Annu. Rev. Neurosci. 30, 317-337.
    • (2007) Annu. Rev. Neurosci. , vol.30 , pp. 317-337
    • Madsen, E.1    Gitlin, J.D.2
  • 32
    • 57149103308 scopus 로고    scopus 로고
    • Zebrafish mutants calamity and catastrophe define critical pathways of gene-nutrient interactions in developmental copper metabolism
    • Madsen, E. C. and Gitlin, J. D. (2008). Zebrafish mutants calamity and catastrophe define critical pathways of gene-nutrient interactions in developmental copper metabolism. PLoS Genet. 4, e1000261.
    • (2008) PLoS Genet. , vol.4
    • Madsen, E.C.1    Gitlin, J.D.2
  • 34
  • 36
    • 30344469388 scopus 로고    scopus 로고
    • In vitro toxicity of copper, cadmium, and chromium to isolated hepatocytes from carp, Cyprinus carpio L
    • Nawaz, M., Manzl, C. and Krumschnabel, G. (2005). In vitro toxicity of copper, cadmium, and chromium to isolated hepatocytes from carp, Cyprinus carpio L. Bull Environ. Contam. Toxicol. 75, 652-661.
    • (2005) Bull Environ. Contam. Toxicol. , vol.75 , pp. 652-661
    • Nawaz, M.1    Manzl, C.2    Krumschnabel, G.3
  • 39
    • 54249085844 scopus 로고    scopus 로고
    • Chemical biology and the limits of reductionism
    • Peterson, R. T. (2008). Chemical biology and the limits of reductionism. Nat. Chem. Biol. 4, 635-638.
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 635-638
    • Peterson, R.T.1
  • 40
    • 0034703872 scopus 로고    scopus 로고
    • The Menkes copper transporter is required for the activation of tyrosinase
    • Petris, M. J., Strausak, D. and Mercer, J. F. (2000). The Menkes copper transporter is required for the activation of tyrosinase. Hum. Mol. Genet. 9, 2845-2851.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2845-2851
    • Petris, M.J.1    Strausak, D.2    Mercer, J.F.3
  • 41
    • 63149194964 scopus 로고    scopus 로고
    • (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
    • Pratilas, C. A., Taylor, B. S., Ye, Q., Viale, A., Sander, C., Solit, D. B. and Rosen, N. (2009). (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. Proc. Natl. Acad. Sci USA 106, 4519-4524.
    • (2009) Proc. Natl. Acad. Sci USA , vol.106 , pp. 4519-4524
    • Pratilas, C.A.1    Taylor, B.S.2    Ye, Q.3    Viale, A.4    Sander, C.5    Solit, D.B.6    Rosen, N.7
  • 42
    • 44749090876 scopus 로고    scopus 로고
    • Cytoskeletal alterations in interphase cells of the green alga Spirogyra decimina in response to heavy metals exposure: II. The effect of aluminium, nickel and copper
    • Pribyl, P., Cepak, V. and Zachleder, V. (2008). Cytoskeletal alterations in interphase cells of the green alga Spirogyra decimina in response to heavy metals exposure: II. The effect of aluminium, nickel and copper. Toxicol. Vitro 22, 1160-1168.
    • (2008) Toxicol. Vitro , vol.22 , pp. 1160-1168
    • Pribyl, P.1    Cepak, V.2    Zachleder, V.3
  • 43
    • 0036898577 scopus 로고    scopus 로고
    • Microarray data normalization and transformation
    • Quackenbush, J. (2002). Microarray data normalization and transformation. Nat. Genet. 32, 496-501.
    • (2002) Nat. Genet. , vol.32 , pp. 496-501
    • Quackenbush, J.1
  • 44
    • 0033617578 scopus 로고    scopus 로고
    • Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase
    • Rae, T. D., Schmidt, P. J., Pufahl, R. A., Culotta, V. C. and O'Halloran, T. V. (1999). Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science 284, 805-808.
    • (1999) Science , vol.284 , pp. 805-808
    • Rae, T.D.1    Schmidt, P.J.2    Pufahl, R.A.3    Culotta, V.C.4    O'Halloran, T.V.5
  • 45
    • 34648828526 scopus 로고    scopus 로고
    • Melanosomes-dark organelles enlighten endosomal membrane transport
    • Raposo, G. and Marks, M. S. (2007). Melanosomes-dark organelles enlighten endosomal membrane transport. Nat. Rev. Mol. Cell Biol. 8, 786-797.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 786-797
    • Raposo, G.1    Marks, M.S.2
  • 46
    • 0033825078 scopus 로고    scopus 로고
    • Zebrafish kit mutation reveals primary and secondary regulation of melanocyte development during fin stripe regeneration
    • Rawls, J. F. and Johnson, S. L. (2000). Zebrafish kit mutation reveals primary and secondary regulation of melanocyte development during fin stripe regeneration. Development 127, 3715-3724.
    • (2000) Development , vol.127 , pp. 3715-3724
    • Rawls, J.F.1    Johnson, S.L.2
  • 47
    • 34548827087 scopus 로고    scopus 로고
    • Global transcriptional responses of fission and budding yeast to changes in copper and iron levels: A comparative study
    • Rustici, G., van Bakel, H., Lackner, D. H., Holstege, F. C., Wijmenga, C., Bahler, J. and Brazma, A. (2007). Global transcriptional responses of fission and budding yeast to changes in copper and iron levels: a comparative study. Genome Biol. 8, R73.
    • (2007) Genome Biol. , vol.8
    • Rustici, G.1    Van Bakel, H.2    Lackner, D.H.3    Holstege, F.C.4    Wijmenga, C.5    Bahler, J.6    Brazma, A.7
  • 49
    • 50649090571 scopus 로고    scopus 로고
    • Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway
    • Sebolt-Leopold, J. S. (2008). Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway. Clin. Cancer Res. 14, 3651-3656.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3651-3656
    • Sebolt-Leopold, J.S.1
  • 50
    • 50649121059 scopus 로고    scopus 로고
    • Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
    • Setty, S. R., Tenza, D., Sviderskaya, E. V., Bennett, D. C., Raposo, G. and Marks, M. S. (2008). Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature 454, 1142-1146.
    • (2008) Nature , vol.454 , pp. 1142-1146
    • Setty, S.R.1    Tenza, D.2    Sviderskaya, E.V.3    Bennett, D.C.4    Raposo, G.5    Marks, M.S.6
  • 53
    • 33745632081 scopus 로고    scopus 로고
    • Peroxisome biogenesis: The peroxisomal endomembrane system and the role of the ER
    • Titorenko, V. I. and Mullen, R. T. (2006). Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER. J. Cell Biol. 174, 11-17.
    • (2006) J. Cell Biol. , vol.174 , pp. 11-17
    • Titorenko, V.I.1    Mullen, R.T.2
  • 54
    • 25144499969 scopus 로고    scopus 로고
    • Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism
    • van Bakel, H., Strengman, E., Wijmenga, C. and Holstege, F. C. (2005). Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol. Genomics 22, 356-367.
    • (2005) Physiol. Genomics , vol.22 , pp. 356-367
    • Van Bakel, H.1    Strengman, E.2    Wijmenga, C.3    Holstege, F.C.4
  • 55
    • 0017407054 scopus 로고
    • Tubulin sulfhydryl groups and polymerization in vitro. Effects of di- And trivalent cations
    • Wallin, M., Larsson, H. and Edstrom, A. (1977). Tubulin sulfhydryl groups and polymerization in vitro. Effects of di- and trivalent cations. Exp. Cell Res.107, 219-225. (Pubitemid 8112732)
    • (1977) Experimental Cell Research , vol.107 , Issue.1 , pp. 219-225
    • Wallin, M.1    Larsson, H.2    Edstrom, A.3
  • 56
    • 14244267510 scopus 로고    scopus 로고
    • Peroxisomal disorders I: Biochemistry and genetics of peroxisome biogenesis disorders
    • Wanders, R. J. and Waterham, H. R. (2005). Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders. Clin. Genet. 67, 107-133.
    • (2005) Clin. Genet. , vol.67 , pp. 107-133
    • Wanders, R.J.1    Waterham, H.R.2
  • 57
    • 33645057693 scopus 로고    scopus 로고
    • Hermansky-Pudlak syndrome: A disease of protein trafficking and organelle function
    • Wei, M. L. (2006). Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function. Pigment Cell Res. 19, 19-42.
    • (2006) Pigment Cell Res. , vol.19 , pp. 19-42
    • Wei, M.L.1
  • 60
    • 57149113921 scopus 로고    scopus 로고
    • Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells
    • Yu, L., Lopez, A., Anaflous, A., El Bali, B., Hamal, A., Ericson, E., Heisler, L. E., McQuibban, A., Giaever, G., Nislow, C. et al. (2008). Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet. 4, e1000284.
    • (2008) PLoS Genet. , vol.4
    • Yu, L.1    Lopez, A.2    Anaflous, A.3    El Bali, B.4    Hamal, A.5    Ericson, E.6    Heisler, L.E.7    McQuibban, A.8    Giaever, G.9    Nislow, C.10
  • 61
    • 0030820818 scopus 로고    scopus 로고
    • Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway
    • Yuan, D. S., Dancis, A. and Klausner, R. D. (1997). Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway. J. Biol. Chem. 272, 25787-25793.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25787-25793
    • Yuan, D.S.1    Dancis, A.2    Klausner, R.D.3
  • 62
    • 55549141877 scopus 로고    scopus 로고
    • Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
    • Zilberman, D., Coleman-Derr, D., Ballinger, T. and Henikoff, S. (2008). Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature 456, 125-129.
    • (2008) Nature , vol.456 , pp. 125-129
    • Zilberman, D.1    Coleman-Derr, D.2    Ballinger, T.3    Henikoff, S.4
  • 63
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • Zon, L. I. and Peterson, R. T. (2005). In vivo drug discovery in the zebrafish. Nat. Rev. Drug Discov. 4, 35-44.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2


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