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Volumn 116, Issue 5, 2010, Pages 851-852

Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TMPRSS6; PROTEINASE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; HEPCIDIN; IDB1 PROTEIN, MOUSE; INHIBITOR OF DIFFERENTIATION 1; IRON; MATRIPTASE 2; MEMBRANE PROTEIN; SERINE PROTEINASE; TFRC PROTEIN, MOUSE; TRANSFERRIN RECEPTOR;

EID: 77956276207     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-04-278655     Document Type: Letter
Times cited : (26)

References (10)
  • 1
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    • Downregulation of Bmp/ Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis
    • Finberg KE, Whittlesey RL, Fleming MD, Andrews NC. Downregulation of Bmp/ Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. Blood. 2010;115(18):3817-3826.
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    • Finberg, K.E.1    Whittlesey, R.L.2    Fleming, M.D.3    Andrews, N.C.4
  • 2
    • 56449096622 scopus 로고    scopus 로고
    • The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
    • Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metab. 2008;8(6):502-511.
    • (2008) Cell Metab , vol.8 , Issue.6 , pp. 502-511
    • Silvestri, L.1    Pagani, A.2    Nai, A.3    De Domenico, I.4    Kaplan, J.5    Camaschella, C.6
  • 3
    • 42649118442 scopus 로고    scopus 로고
    • Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
    • Finberg KE, Heeney MM, Campagna DR, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008;40(5):569-571.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 569-571
    • Finberg, K.E.1    Heeney, M.M.2    Campagna, D.R.3
  • 4
    • 54349096688 scopus 로고    scopus 로고
    • Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
    • Folgueras AR, de Lara FM, Pendas AM, et al. Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis. Blood. 2008;112(6):2539-2545.
    • (2008) Blood , vol.112 , Issue.6 , pp. 2539-2545
    • Folgueras, A.R.1    De Lara, F.M.2    Pendas, A.M.3
  • 6
    • 54349094273 scopus 로고    scopus 로고
    • A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron
    • Melis MA, Cau M, Congiu R, et al. A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron. Haematologica. 2008; 93(10):1473-1479.
    • (2008) Haematologica , vol.93 , Issue.10 , pp. 1473-1479
    • Melis, M.A.1    Cau, M.2    Congiu, R.3
  • 7
    • 70350628958 scopus 로고    scopus 로고
    • Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
    • Benyamin B, Ferreira MA, Willemsen G, et al. Common variants in TMPRSS6 are associated with iron status and erythrocyte volume. Nat Genet. 2009; 41(11):1173-1175.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1173-1175
    • Benyamin, B.1    Ferreira, M.A.2    Willemsen, G.3
  • 8
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    • Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels
    • Chambers JC, Zhang W, Li Y, et al. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet. 2009; 41(11):1170-1172.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1170-1172
    • Chambers, J.C.1    Zhang, W.2    Li, Y.3
  • 9
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    • Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
    • Ganesh SK, Zakai NA, van Rooij FJ, et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet. 2009;41(11):1191- 1198.
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  • 10
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    • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
    • Soranzo N, Spector TD, Mangino M, et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet. 2009;41(11):1182-1190.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1182-1190
    • Soranzo, N.1    Spector, T.D.2    Mangino, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.