Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy

Genesis (United States)

Volumn 44, Issue 5, 2006, Pages 239-251

  Dufner Beattie, Jodi ^a,b   Huang, Zhixin L ^a   Geiser, Jim ^a   Xu, Wenhao ^a,c   Andrews, Glen K ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b Apath LLC   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Knockout; Mouse; SLC39A1; SLC39A3; Zinc deficiency

Indexed keywords

COMPLEMENTARY DNA; ENHANCED GREEN FLUORESCENT PROTEIN; MESSENGER RNA; METALLOTHIONEIN I; PROTEIN SLC39A1; PROTEIN SLC39A3; THYMIDINE KINASE; UNCLASSIFIED DRUG; ZINC TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; INTESTINE CELL; KIDNEY TUBULE EPITHELIUM; KNOCKOUT MOUSE; LIVER CELL; LOXP SITE; MOUSE; NONHUMAN; NUTRITIONAL DEFICIENCY; OPEN READING FRAME; PANCREAS CELL; PHENOTYPE; PLEIOTROPY; POLYADENYLATION; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SOUTHERN BLOTTING; STOP CODON; WESTERN BLOTTING; WILD TYPE; ZINC DEFICIENCY; ZIP1 GENE; ZIP3 GENE;

EID: 33745040492     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20211     Document Type: Article

References (59)

1. Allen LH. 1998. Zinc and micronutrient supplements for children. Am J Clin Nutr 68(Suppl):495S-498S.
2. Andrews RCR. 1992. Diabetes and schizophrenia: Genes or zinc deficiency. Lancet 340:1160.
3. Andrews GK, Geiser J. 1999. Expression of metallothionein-I and -II genes provides a reproductive advantage during maternal dietary zinc deficiency. J Nutr 129:1643-1648.
4. Andrews GK, Huet-Hudson YM, Paria BC, McMaster MT, De SK, Dey SK. 1991. Metallothionein gene expression and metal regulation during preimplantation mouse embryo development (MT mRNA during early development). Dev Biol 145:13-27.
5. Andrews GK, Wang H, Dey SK, Palmiter RD. 2004. The mouse zinc transporter 1 gene provides an essential function during early embryonic development. genesis 40:74-81.
6. Apgar J. 1970. Effect of zinc deficiency on maintenance of pregnancy in the rat. J Nutr 100:470-476.
7. Apgar J. 1985. Zinc and reproduction. Annu Rev Nutr 5:43-68.
8. Barthel LK, Raymond PA. 1990. Improved method for obtaining 3-microns cryosections for immunocytochemistry. J Histochem Cytochem 38:1383-1388.
9. Black MM. 1998a. Zinc deficiency and child development. Am J Clin Nutr 68(Suppl):464S-469S.
10. Black RE. 1998b. Therapeutic and preventive effects of zinc on serious childhood infectious diseases in developing countries. Am J Clin Nutr 68(Suppl):476S-479S.
11. Black RE. 2003. Zinc deficiency, infectious disease and mortality in the developing world. J Nutr 133:1485S-1489S.
12. Bloxam DL, Bax CMR. 1996. Zinc deficiency and abnormal fetal development: Assessment of maternal or fetal zinc status. Am J Obstet Gynecol 175:1078.
13. Cao J, Bobo JA, Liuzzi JP, Cousins RJ. 2001. Effects of intracellular zinc depletion on metallothionein and ZIP2 transporter expression and apoptosis. J Leukoc Biol 70:559-566.
14. Caulfield LE, Zavaleta N, Shankar AH, Merialdi M. 1998. Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival. Am J Clin Nutr 68(Suppl):499S-508S.
15. Cousins RJ, Blanchard RK, Popp MP, Liu L, Cao J, Moore JB, Green CL. 2003. A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells. Proc Natl Acad Sci U S A 100:6952-6957.
16. Dalton TP, Fu K, Palmiter RD, Andrews GK. 1996. Transgenic mice that over-express metallothionein-I resist dietary zinc deficiency. J Nutr 126:825-833.
17. Dalton TP, He L, Wang B, Miller ML, Jin L, Stringer KF, Chang X, Baxter CS, Nebert DW. 2005. Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc Natl Acad Sci U S A 102:3401-3406.
18. Dufner-Beattie J, Langmade SJ, Wang F, Eide D, Andrews GK. 2003a. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J Biol Chem 278:50142-50150.
19. Dufner-Beattie J, Wang F, Kuo YM, Gitschler J, Eide D, Andrews GK. 2003b. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J Biol Chem 278:33474-33481.
20. Dufner-Beattie J, Kuo YM, Gitschier J, Andrews GK. 2004. The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc-regulation of the zinc transporters ZIP4 and ZIP5. J Biol Chem 279:49082-49090.
21. Dufner-Beattie J, Huang ZL, Geiser J, Xu W, Andrews GK. 2005. Generation and characterization of mice lacking the zinc uptake transporter ZIP3. Mol Cell Biol 25:5607-5615.
22. Eng BH, Guerinot ML, Eide D, Saier MH Jr. 1998. Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins. J Membr Biol 166:1-7.
23. Franklin RB, Ma J, Zou J, Guan Z, Kukoyi BI, Feng P, Costello LC. 2003. Human ZIP1 is a major zinc uptake transporter for the accumulation of zinc in prostate cells. J Inorg Biochem 96:435-442.
24. Franklin RB, Feng P, Milon B, Desouki MM, Singh KK, Kajdacsy-Balla A, Bagasra O, Costello LC. 2005. hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer. Mol Cancer 4:32-45.
25. Gaither LA, Eide DJ. 2001. The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells. J Biol Chem 276:22258-22264.
26. Godwin AR, Stadler HS, Nakamura K, Capecchi MR. 1998. Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proc Natl Acad Sci U S A 95:13042-13047.
27. Guerinot ML. 2000. The ZIP family of metal transporters. Biochim Biophys Acta 1465:190-198.
28. Hambidge KM, Krebs NF. 2003. Zinc, low birth weight, and breastfeeding. Pediatrics 112:1419-1420.
29. Harding AJ, Dreosti IE, Tulsi RS. 1988. Zinc deficiency in the 11 day rat embryo: a scanning and transmission electron microscope study. Life Sci 42:889-896.
30. Huang ZL, Dufner-Beattie J, Andrews GK. 2006. Expression and regulation of SLC39A family zinc transporters in the developing mouse intestine. Dev Biol (in press).
31. Hurley LS. 1981. The roles of trace elements in foetal and neonatal development. Philos Trans R Soc Lond B Biol Sci 294:145-152.
32. Hurley LS, Swenerton H. 1966. Congenital malformations resulting from zinc deficiency in rats. Proc Soc Exp Biol Med 123:692-696.
33. Hurley LS, Gowen J, Swenerton H. 1971. Teratogenic effects of short-term and transitory zinc deficiency in rats. Teratology 4:199-204.
34. Kelleher SL, Lonnerdal B. 2005. Zip3 plays a major role in zinc uptake into mammary epithelial cells and is regulated by prolactin. Am J Physiol Cell Physiol 288:C1042-C1047.
35. Khadeer MA, Sahu SN, Bai G, Abdulla S, Gupta A. 2005. Expression of the zinc transporter ZIP1 in osteoclasts. Bone 3:296-304.
36. Krotova KY, Zharikov SI, Block ER. 2003. Classical isoforms of PKC as regulators of CAT-1 transporter activity in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 284:L1037-L1044.
37. Kury S, Dreno B, Bezieau S, Giraudet S, Kharfi M, Kamoun R, Moisan JP. 2002. Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat Genet 31:239-240.
38. Lamar EE, Palmer E. 1984. Y-encoded, species-specific DNA in mice: evidence that the Y chromosome exists in two polymorphic forms in inbred strains. Cell 37:171-177.
39. Lee DK, Geiser J, Dufner-Beattie J, Andrews GK. 2003. Pancreatic metallothionein-1 may play a role in zinc homeostasis during maternal dietary zinc deficiency in mice. J Nutr 133:45-50.
40. Mathews WR, Wang F, Eide DJ, Van Doren M. 2005. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem 280:787-795.
41. Neggers YH, Cutter GR, Acton RT, Alvarez JO, Bonner JL, Goldenberg RL, Go RCP, Roseman JM. 1990. A positive association between maternal serum zinc concentration and birth weight. Am J Clin Nutr 51:678-684.
42. Palmiter RD. 1998. The elusive function of metallothioneins. Proc Natl Acad Sci U S A 95:8428-8430.
43. Palmiter RD, Findley SD. 1995. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J 14:639-649.
44. Palmiter RD, Huang L. 2004. Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers. Pflugers Arch Eur J Physiol 447:744-751.
45. Prasad AS. 1996. Zinc deficiency in women, infants and children. J Am Coll Nutr 15:113-120.
46. Prasad AS. 1998a. Zinc deficiency in humans: a neglected problem. J Am Coll Nutr 17:542-543.
47. Prasad AS. 1998b. Zinc in human health: an update. J Trace Elem Exp Med 11:63-87.
48. Prasad AS. 2003. Zinc deficiency has been known of for 40 years but ignored by global health organisations. Br Med J 326:409-410.
49. Ravasi T, Huber T, Zavolan M, Forrest A, Gaasterland T, Grimmond S, Hume DA, Riken GG, Members GSL. 2003. Systematic characterization of the zinc-finger-containing proteins in the mouse transcriptome. Genome Res 13:1430-1442.
50. Rodriguez E, Pulido N, Romero R, Arrieta F, Panadero A, Rovira A. 2004. Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle. Endocrinology 145:679-685.
51. Sagawa N, Fujita H, Banno Y, Nozawa Y, Katoh H, Kuzumaki N. 2003. Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10. Br J Cancer 88:606-612.
52. Salgueiro MJ, Weill R, Zubillaga M, Lysionek A, Caro R, Goldman C, Barrado D, Sarrasague MM, Boccio J. 2004. Zinc deficiency and growth-current concepts in relationship to two important points: Intellectual and sexual development. Biol Trace Elem Res 99:49-69.
53. Seve M, Chimienti F, Devergnas S, Favier A. 2004. In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression. BMC Genomics 5:32.
54. Tamura T, Goldenberg RL, Johnston KE, DuBard M. 2000. Maternal plasma zinc concentrations and pregnancy outcome. Am J Clin Nutr 71:109-113.
55. Taylor KM, Nicholson RI. 2003. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim Biophys Acta 1611:16-30.
56. Walsh CT, Sandstead HH, Prasad AS, Newberne PM, Fraker PJ. 1994. Zinc: health effects and research priorities for the 1990s. Environ Health Perspect 102(Suppl 2):5-46.
57. Wang K, Zhou B, Kuo Y-M, Gitschier J. 2002. A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am J Hum Genet 71:66-73.
58. Wang F, Dufner-Beattie J, Kim BE, Petris MJ, Andrews G, Eide DJ. 2004. Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters. J Biol Chem 279:24631-24639.
59. Yamashita S, Miyagi C, Fukada T, Kagara N, Che YS, Hirano T. 2004. Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer. Nature 429:298-302.