-
1
-
-
4143051431
-
Transferrin receptor 1
-
Aisen P. Transferrin receptor 1. Int J Biochem Cell Biol. 2004;36:2137-2143.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2137-2143
-
-
Aisen, P.1
-
2
-
-
0032477866
-
Nramp2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A. 1998;95:1148-1153.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
3
-
-
0027279873
-
Transferrin and the transferrin cycle in Belgrade rat reticulocytes
-
Garrick MD, Gniecko K, Liu Y, Cohan DS, Garrick LM. Transferrin and the transferrin cycle in Belgrade rat reticulocytes. J Biol Chem. 1993;268: 14867-14874.
-
(1993)
J Biol Chem
, vol.268
, pp. 14867-14874
-
-
Garrick, M.D.1
Gniecko, K.2
Liu, Y.3
Cohan, D.S.4
Garrick, L.M.5
-
4
-
-
0033597780
-
Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, et al. Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. J Biol Chem. 1999;274:20826-20832.
-
(1999)
J Biol Chem
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
-
5
-
-
0034595856
-
Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo
-
Kawabata H, Germain RS, Vuong PT, Nakamaki T, Said JW, Koeffler HP. Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo. J Biol Chem. 2000;275: 16618-16625.
-
(2000)
J Biol Chem
, vol.275
, pp. 16618-16625
-
-
Kawabata, H.1
Germain, R.S.2
Vuong, P.T.3
Nakamaki, T.4
Said, J.W.5
Koeffler, H.P.6
-
6
-
-
0034623930
-
Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE
-
West AP Jr, Bennett MJ, Sellers VM, Andrews NC, Enns CA, Bjorkman PJ. Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. J Biol Chem. 2000;275:38135-38138.
-
(2000)
J Biol Chem
, vol.275
, pp. 38135-38138
-
-
West Jr, A.P.1
Bennett, M.J.2
Sellers, V.M.3
Andrews, N.C.4
Enns, C.A.5
Bjorkman, P.J.6
-
7
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell. 2004;117:285-297.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
8
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090-2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
9
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037-1044.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
10
-
-
1642386686
-
Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates
-
Shike H, Shimizu C, Lauth X, Burns JC. Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates. Dev Comp Immunol. 2004;28:747-754.
-
(2004)
Dev Comp Immunol
, vol.28
, pp. 747-754
-
-
Shike, H.1
Shimizu, C.2
Lauth, X.3
Burns, J.C.4
-
11
-
-
0035896581
-
Anew mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is over expressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al. Anew mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is over expressed during iron overload. J Biol Chem. 2001;276:7811-7819.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
12
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet. 2003;361:669-673.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
13
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood. 2005;105:1803-1806.
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
14
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet. 2003;33:21-22.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
15
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004;36:77-82.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
16
-
-
33646337674
-
Iron metabolism meets signal transduction
-
Anderson GJ, Frazer DM. Iron metabolism meets signal transduction. Nat Genet. 2006;38:503-504.
-
(2006)
Nat Genet
, vol.38
, pp. 503-504
-
-
Anderson, G.J.1
Frazer, D.M.2
-
17
-
-
0037114751
-
The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1)
-
Donovan A, Brownlie A, Dorschner MO, et al. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood. 2002; 100:4655-4659.
-
(2002)
Blood
, vol.100
, pp. 4655-4659
-
-
Donovan, A.1
Brownlie, A.2
Dorschner, M.O.3
-
18
-
-
19944426386
-
The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1
-
Wingert RA, Brownlie A, Galloway JL, et al. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development. 2004;131:6225-6235.
-
(2004)
Development
, vol.131
, pp. 6225-6235
-
-
Wingert, R.A.1
Brownlie, A.2
Galloway, J.L.3
-
19
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 2000; 403:776-781.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
20
-
-
20444464809
-
Ferroportin1 is required for normal iron cycling in zebrafish
-
Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. Ferroportin1 is required for normal iron cycling in zebrafish. J Clin Invest. 2005;115:1532-1541.
-
(2005)
J Clin Invest
, vol.115
, pp. 1532-1541
-
-
Fraenkel, P.G.1
Traver, D.2
Donovan, A.3
Zahrieh, D.4
Zon, L.I.5
-
21
-
-
30144432585
-
The N-terminus of hepcidin is essential for its interaction with ferroportin: Structure- function study
-
Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure- function study. Blood. 2006;107:328-333.
-
(2006)
Blood
, vol.107
, pp. 328-333
-
-
Nemeth, E.1
Preza, G.C.2
Jung, C.L.3
Kaplan, J.4
Waring, A.J.5
Ganz, T.6
-
23
-
-
0032559307
-
Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation
-
Zhang J, Talbot WS, Schier AF. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell. 1998;92:241-251.
-
(1998)
Cell
, vol.92
, pp. 241-251
-
-
Zhang, J.1
Talbot, W.S.2
Schier, A.F.3
-
24
-
-
0030969949
-
Morpholino and phosphorothioate antisense oligomers compared in cell- free and in-cell systems
-
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M. Morpholino and phosphorothioate antisense oligomers compared in cell- free and in-cell systems. Antisense Nucleic Acid Drug Dev. 1997;7:63-70.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 63-70
-
-
Summerton, J.1
Stein, D.2
Huang, S.B.3
Matthews, P.4
Weller, D.5
Partridge, M.6
-
25
-
-
33749208496
-
Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
-
Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast. 2000;17:294-301.
-
(2000)
Yeast
, vol.17
, pp. 294-301
-
-
Nasevicius, A.1
Larson, J.2
Ekker, S.C.3
-
26
-
-
11244264337
-
Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos
-
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Dev Cell. 2005;8:109-116.
-
(2005)
Dev Cell
, vol.8
, pp. 109-116
-
-
Galloway, J.L.1
Wingert, R.A.2
Thisse, C.3
Thisse, B.4
Zon, L.I.5
-
27
-
-
16644391747
-
Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening
-
Thisse B, Heyer V, Lux A, et al. Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening. Methods Cell Biol. 2004;77:505-519.
-
(2004)
Methods Cell Biol
, vol.77
, pp. 505-519
-
-
Thisse, B.1
Heyer, V.2
Lux, A.3
-
28
-
-
12644292903
-
Characterization of zebrafish mutants with defects in embryonic hematopoiesis
-
Ransom DG, Haffter P, Odenthal J, et al. Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development. 1996;123: 311-319.
-
(1996)
Development
, vol.123
, pp. 311-319
-
-
Ransom, D.G.1
Haffter, P.2
Odenthal, J.3
-
29
-
-
34548406422
-
Huntingtin-deficient zebrafish exhibit defects in iron utilization and development
-
Lumsden AL, Henshall TL, Dayan S, Lardelli MT, Richards RI. Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Hum Mol Genet. 2007;16:1905-1920.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1905-1920
-
-
Lumsden, A.L.1
Henshall, T.L.2
Dayan, S.3
Lardelli, M.T.4
Richards, R.I.5
-
30
-
-
0035883938
-
Developmental expression of cytochrome P450 aromatase genes (CYP19a and CYP19b) in zebrafish fry (Daniorerio)
-
Trant JM, Gavasso S, Ackers J, Chung BC, Place AR. Developmental expression of cytochrome P450 aromatase genes (CYP19a and CYP19b) in zebrafish fry (Daniorerio). J Exp Zool. 2001;290:475-483.
-
(2001)
J Exp Zool
, vol.290
, pp. 475-483
-
-
Trant, J.M.1
Gavasso, S.2
Ackers, J.3
Chung, B.C.4
Place, A.R.5
-
31
-
-
0030817790
-
Rapid identification and isolation of zebrafish cDNA clones
-
Gong Z, Yan T, Liao J, Lee SE, He J, Hew CL. Rapid identification and isolation of zebrafish cDNA clones. Gene. 1997;201:87-98.
-
(1997)
Gene
, vol.201
, pp. 87-98
-
-
Gong, Z.1
Yan, T.2
Liao, J.3
Lee, S.E.4
He, J.5
Hew, C.L.6
-
32
-
-
2142717415
-
Expression analyses of zebrafish transferrin, ifabp, and elastaseB mRNAs as differentiation markers for the three major endodermal organs: Liver, intestine, and exocrine pancreas
-
Mudumana SP, Wan H, Singh M, Korzh V, Gong Z. Expression analyses of zebrafish transferrin, ifabp, and elastaseB mRNAs as differentiation markers for the three major endodermal organs: liver, intestine, and exocrine pancreas. Dev Dyn. 2004;230:165-173.
-
(2004)
Dev Dyn
, vol.230
, pp. 165-173
-
-
Mudumana, S.P.1
Wan, H.2
Singh, M.3
Korzh, V.4
Gong, Z.5
-
33
-
-
0037434880
-
In vivo studies of liver-type fatty acid binding protein (L- FABP) gene expression in liver of transgenic zebrafish (Danio rerio)
-
Her GM, Chiang CC, Chen WY, Wu JL. In vivo studies of liver-type fatty acid binding protein (L- FABP) gene expression in liver of transgenic zebrafish (Danio rerio). FEBS Lett. 2003;538:125-133.
-
(2003)
FEBS Lett
, vol.538
, pp. 125-133
-
-
Her, G.M.1
Chiang, C.C.2
Chen, W.Y.3
Wu, J.L.4
-
34
-
-
0037406254
-
Colocalization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells
-
Griffiths WJ, Cox TM. Colocalization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells. J Histochem Cytochem. 2003;51:613-624.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 613-624
-
-
Griffiths, W.J.1
Cox, T.M.2
-
35
-
-
0036838570
-
Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
-
Dupic F, Fruchon S, Bensaid M, et al. Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice. Gut. 2002;51:648-653.
-
(2002)
Gut
, vol.51
, pp. 648-653
-
-
Dupic, F.1
Fruchon, S.2
Bensaid, M.3
-
36
-
-
33845245942
-
Suppression of hepcidin during anemia requires erythropoietic activity
-
Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood. 2006;108:3730-3735.
-
(2006)
Blood
, vol.108
, pp. 3730-3735
-
-
Pak, M.1
Lopez, M.A.2
Gabayan, V.3
Ganz, T.4
Rivera, S.5
-
38
-
-
0027360042
-
Studies on familial hypotransferrinemia: Unique clinical course and molecular pathology
-
Hayashi A, Wada Y, Suzuki T, Shimizu A. Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am J Hum Genet. 1993;53:201-213.
-
(1993)
Am J Hum Genet
, vol.53
, pp. 201-213
-
-
Hayashi, A.1
Wada, Y.2
Suzuki, T.3
Shimizu, A.4
-
39
-
-
0034585942
-
Biochemical and genetic defects underlying human congenital hypotransferrinemia
-
Goldwurm S, Casati C, Venturi N, et al. Biochemical and genetic defects underlying human congenital hypotransferrinemia. Hematol J. 2000;1: 390-398.
-
(2000)
Hematol J
, vol.1
, pp. 390-398
-
-
Goldwurm, S.1
Casati, C.2
Venturi, N.3
-
40
-
-
36348972935
-
Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia
-
Trombini P, Coliva T, Nemeth E, et al. Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia. Haematologica. 2007;92:1407-1410.
-
(2007)
Haematologica
, vol.92
, pp. 1407-1410
-
-
Trombini, P.1
Coliva, T.2
Nemeth, E.3
-
41
-
-
0034254752
-
The molecular defect in hypotransferrinemic mice
-
Trenor CC, 3rd Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice. Blood. 2000;96: 1113-1118.
-
(2000)
Blood
, vol.96
, pp. 1113-1118
-
-
Trenor 3rd, C.C.1
Campagna, D.R.2
Sellers, V.M.3
Andrews, N.C.4
Fleming, M.D.5
-
42
-
-
0023522698
-
Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia
-
Bernstein SE. Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia. J Lab Clin Med. 1987; 110:690-705.
-
(1987)
J Lab Clin Med
, vol.110
, pp. 690-705
-
-
Bernstein, S.E.1
-
44
-
-
0013984436
-
Atransferrinemias]
-
Heilmeyer L. [Atransferrinemias]. Acta Haematol. 1966;36:40-49.
-
(1966)
Acta Haematol
, vol.36
, pp. 40-49
-
-
Heilmeyer, L.1
-
45
-
-
0037369165
-
-
Roy CN, Weinstein DA, Andrews NC. 2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis. Pediatr Res. 2003; 53:507-512.
-
Roy CN, Weinstein DA, Andrews NC. 2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis. Pediatr Res. 2003; 53:507-512.
-
-
-
-
46
-
-
34548825938
-
Iron-transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4
-
Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T. Iron-transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 2007; 110:2182-2189.
-
(2007)
Blood
, vol.110
, pp. 2182-2189
-
-
Lin, L.1
Valore, E.V.2
Nemeth, E.3
Goodnough, J.B.4
Gabayan, V.5
Ganz, T.6
-
47
-
-
73049141429
-
Congenital atransferrinemia in a 7-year-old girl.]
-
Heilmeyer L, Keller W, Vivell O, et al. [Congenital atransferrinemia in a 7-year-old girl.]. Dtsch Med Wochenschr. 1961;86:1745-1751.
-
(1961)
Dtsch Med Wochenschr
, vol.86
, pp. 1745-1751
-
-
Heilmeyer, L.1
Keller, W.2
Vivell, O.3
-
48
-
-
33846225653
-
Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload
-
Wallace DF, Summerville L, Subramaniam VN. Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload. Gastroenterology. 2007;132:301-310.
-
(2007)
Gastroenterology
, vol.132
, pp. 301-310
-
-
Wallace, D.F.1
Summerville, L.2
Subramaniam, V.N.3
-
49
-
-
1942445099
-
Homozygosity for transferrin receptor-2 Y250X mutation induces early iron overload
-
Piperno A, Roetto A, Mariani R, et al. Homozygosity for transferrin receptor-2 Y250X mutation induces early iron overload. Haematologica. 2004;89:359-360.
-
(2004)
Haematologica
, vol.89
, pp. 359-360
-
-
Piperno, A.1
Roetto, A.2
Mariani, R.3
-
50
-
-
33749393565
-
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
-
Goswami T, Andrews NC. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing. J Biol Chem. 2006;281: 28494-28498.
-
(2006)
J Biol Chem
, vol.281
, pp. 28494-28498
-
-
Goswami, T.1
Andrews, N.C.2
-
51
-
-
2542560427
-
Hereditary hemochromatosis-a new look at an old disease
-
Pietrangelo A. Hereditary hemochromatosis-a new look at an old disease. N Engl J Med. 2004; 350:2383-2397.
-
(2004)
N Engl J Med
, vol.350
, pp. 2383-2397
-
-
Pietrangelo, A.1
-
52
-
-
0035914480
-
Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites
-
West AP, Jr., Giannetti AM, Herr AB, et al. Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites. J Mol Biol. 2001;313:385-397.
-
(2001)
J Mol Biol
, vol.313
, pp. 385-397
-
-
West Jr., A.P.1
Giannetti, A.M.2
Herr, A.B.3
-
53
-
-
27844495743
-
Agenomewide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish
-
Sambrook JG, Figueroa F, Beck S. Agenomewide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish. BMC Genomics. 2005;6:152.
-
(2005)
BMC Genomics
, vol.6
, pp. 152
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-
Sambrook, J.G.1
Figueroa, F.2
Beck, S.3
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