Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia

Blood

Volumn 119, Issue 21, 2012, Pages 5021-5029

  Nai, Antonella ^a,b   Pagani, Alessia ^a,b   Mandelli, Giacomo ^c   Lidonnici, Maria Rosa ^a,c   Silvestri, Laura ^a,b   Ferrari, Giuliana ^a,c   Camaschella, Clara ^a,b  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 6; HEMOGLOBIN; HEPCIDIN; INHIBITOR OF DIFFERENTIATION 1; IRON; MEMBRANE PROTEIN; MESSENGER RNA; SERINE PROTEINASE; SMAD7 PROTEIN; TRANSMEMBRANE PROTEASE SERINE 6; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BETA THALASSEMIA; ERYTHROCYTE COUNT; ERYTHROPOIESIS; FEMALE; GENE DELETION; HAPLOINSUFFICIENCY; HEMOGLOBIN BLOOD LEVEL; HOMOZYGOSITY; IRON ABSORPTION; IRON OVERLOAD; MALE; MICROCYTOSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SEX DIFFERENCE; SPLEEN SIZE; SPLENOMEGALY; UPREGULATION;

EID: 84861525631     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-401885     Document Type: Article

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